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Results of using intraoperative ultrasound in surgery of neurodegenerative disorders of the lumbar spine 术中超声在腰椎神经退行性疾病手术中的应用效果
Pub Date : 2023-10-20 DOI: 10.17650/1683-3295-2023-25-3-59-68
M. N. Aslanukov, S. A. Vasilyev, R. S. Levin, S. K. Oshchepkov
Aim. To evaluate the results of intraoperative ultrasound examination (IOUS) in surgery of degenerative diseases of the lumbar spine. Materials and methods. To evaluate the results of the use of IOUS in the surgery of degenerative diseases of the lumbar spine, an analysis of prospective examination data of 147 patients operated on for degenerative diseases of the lumbar spine in the neurosurgical department of the B.V. Petrovsky National Research Center of Surgery from 2014 to 2018. To study the accuracy of the ultrasound method for determining the level of surgical access and assessing the degree of radiation load reduction, to study the quality of ultrasound imaging of the structures of the spinal canal, a descriptive study was conducted that included 100 patients (a group of method descriptions). To determine the effectiveness of the use of IOUS, a randomized controlled trial was conducted based on a statistical comparison of the results of surgical treatment of 2 similar parallel groups of patients (control and experimental) consisting of 47 patients each, who differed only in the use of IOUS. Patients of the control group were selected from the method description group. The control and experimental groups of patients were compared according to the following criteria: the duration of surgery, the volume of intraoperative blood loss, the duration of hospitalization, the degree of root pain after surgery, the level of quality of life after surgery, the number of recurrences of herniated disc. For IOUS, we used BK Medical Pro Focus 2202 and BK Medical Flex Focus 400 ultrasound machines with neurosurgical sensors Craniotomy 8862 and Burr-Hole 8863. We performed IOUS before flavotomy, after flavotomy and after decompression of nerve structures. Results. The method of determining the level of surgical access using IOUS has a high accuracy (100 %) and allows you not to use radiography and reduce the radiation load (on average by 0.02 mSv per patient). IOUS allows to adequately visualize the structures of the spinal canal in patients with degenerative pathology of the lumbar spine: the sensitivity of the method before flavotomy is 93 %, after flavotomy – 97 %, and after decompression of nerve structures – 100 %. Due to the high sensitivity of the IOUS method, it allows optimizing surgical access, controlling the radicality of decompression of nerve structures, documenting the fact of their decompression. The use of IOUS in patients with degenerative diseases of the lumbar spine can improve the results of surgical treatment by reducing the number of recurrences of disc herniation, reducing the degree of radicular pain after surgery, reducing the duration of surgery and the volume of intraoperative blood loss. Conclusion. IOUS is a simple, harmless and widely available method of intraoperative imaging, which allows to improve the results of surgical treatment of patients with degenerative pathology of the lumbar spine.
的目标。目的探讨术中超声检查在腰椎退行性疾病手术中的应用价值。材料和方法。为评价借条在腰椎退行性疾病手术中的应用效果,对2014 - 2018年B.V. Petrovsky国家外科研究中心神经外科147例腰椎退行性疾病手术患者的前瞻性检查资料进行分析。为了研究超声方法在确定手术通路水平和评估放射负荷降低程度方面的准确性,为了研究椎管结构超声成像的质量,我们进行了一项包括100例患者(一组方法描述)的描述性研究。为确定借条使用的有效性,对两组相似的患者(对照组和实验组)各47例患者的手术治疗结果进行统计比较,进行随机对照试验,两组患者仅在使用借条方面存在差异。对照组患者从方法描述组中选取。参照手术时间、术中出血量、住院时间、术后牙根痛程度、术后生活质量水平、椎间盘突出症复发次数,比较对照组和实验组患者的差异。对于白条,我们使用了BK Medical Pro Focus 2202和BK Medical Flex Focus 400带神经外科传感器的超声机Craniotomy 8862和Burr-Hole 8863。我们分别在黄腔切开术前、黄腔切开术后和神经结构减压后进行了欠条手术。结果。使用借据确定手术通道水平的方法具有很高的准确性(100%),并且允许您不使用放射照相并减少辐射负荷(平均每名患者减少0.02毫西弗)。在腰椎退行性病变患者中,IOUS可以充分显示椎管结构:该方法在黄腔切开术前的灵敏度为93%,黄腔切开术后的灵敏度为97%,神经结构减压后的灵敏度为100%。由于IOUS方法的高灵敏度,它可以优化手术通路,控制神经结构减压的激进性,记录其减压的事实。腰椎退行性疾病患者使用白条可减少椎间盘突出的复发次数,减轻术后神经根疼痛程度,缩短手术时间,减少术中出血量,从而提高手术治疗效果。结论。欠条是一种简单、无害且广泛应用的术中成像方法,可提高腰椎退行性病理患者的手术治疗效果。
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引用次数: 0
Anterior lumbar interbody fusion (ALIF): a review of the procedure and associated complications 腰椎前路椎体间融合术(ALIF):手术和相关并发症的回顾
Pub Date : 2023-10-19 DOI: 10.17650/1683-3295-2023-25-3-119-125
G. Musa, R.E. B. Castillo, D.T. K. Ndandja, B. M. Mwela, G. E. Chmutin, G. I. Antonov, M. V. Slabov
Degenerative disc disease and facet joint disease involving the lumbar spine are common in the aging population and are the most frequent causes of disability. Surgical interbody fusion of degenerative levels is the most common management technique. This is an effective treatment option to stabilize the spine and reduce mechanical pain and provides indirect decompression of the neural elements while restoring lordosis and correcting the deformity. Depending on the direction of the approach to the vertebral column, various techniques have been described. Anterior lumbar interbody fusion (ALIF) offers clear and wide visualization of the disc allowing the use of large interbody grafts, which provide a significant biomechanical advantage over other types of fusion. The transperitoneal approach is a much older technique and it is not commonly performed unless in isolated cases with extensive retroperitoneal scaring following multiple abdominal surgeries. The transperitoneal approach has been associated with higher rates of bowel injury, ileus, and retrograde ejaculation, and is limited at the L5–S1 segment, hence many spine surgeons favor a retroperitoneal approach. The major setback of ALIF is the need for great vessel mobilization. This manipulation of the vessels may lead to deep vein thrombosis and a direct vascular injury. This makes vascular anatomy studies in the preoperative stage invaluable in avoiding vascular injury. Other complications include possible injury to intraperitoneal and retroperitoneal organs, especially in patients with previous surgery and adhesions. Manipulation of the intestines causes postoperative ileus which lasts a few days. Sexual dysfunction in form of retrograde ejaculation is another complication seen in patients following ALIF and this has been attributed to injury to the superior hypogastric sympathetic nerves in the lower lumbar region. This article reviews the ALIF procedure i. e., transperitoneal and retroperitoneal approaches, and the associated intraoperative, early, and late complications.
椎间盘退行性疾病和腰椎小关节疾病在老年人中很常见,也是最常见的致残原因。退行性椎体间融合术是最常见的治疗方法。这是一种有效的治疗选择,可以稳定脊柱,减少机械性疼痛,并在恢复前凸和纠正畸形的同时提供神经元件的间接减压。根据椎体入路的方向,已经描述了各种技术。腰椎前路椎体间融合术(ALIF)提供了清晰和宽阔的椎间盘显像,允许使用大型椎体间移植物,这比其他类型的融合术提供了显著的生物力学优势。经腹膜入路是一种更古老的技术,除非在多次腹部手术后出现广泛腹膜后瘢痕的孤立病例,否则通常不采用该方法。经腹膜入路与肠损伤、肠梗阻和逆行射精的发生率较高有关,并且限于L5-S1节段,因此许多脊柱外科医生倾向于采用腹膜后入路。ALIF的主要挫折是需要大量的船只动员。这种对血管的操作可能导致深静脉血栓形成和直接的血管损伤。这使得术前血管解剖研究在避免血管损伤方面具有不可估量的价值。其他并发症包括可能对腹膜内和腹膜后器官的损伤,特别是在既往手术和粘连的患者中。对肠道的操作导致术后肠梗阻,持续几天。以逆行射精形式出现的性功能障碍是ALIF患者的另一种并发症,这是由于下腰部区域的胃下交感神经损伤所致。本文回顾了ALIF手术,即经腹膜和后腹膜入路,以及相关的术中、早期和晚期并发症。
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引用次数: 0
Neurological disorders imitating spinal stenosis in elderly patients. Series of clinical observations 老年患者类似椎管狭窄的神经障碍。一系列临床观察
Pub Date : 2023-10-19 DOI: 10.17650/1683-3295-2023-25-3-100-110
E. G. Seliverstova, A. Y. Kordonskiy, E. S. Druzhinina, E. K. Romanenko, A. A. Grin
Spinal stenosis is a pathological narrowing of the central spinal canal, lateral pocket, or intervertebral foramen due to age‑related changes, including pathology of the discs, facet joints, ligament hypertrophy, osteophyte formation and destruction of the arches. Clinically, the disease can manifest itself with pain, as well as numbness, or weakness in the arms or legs. The complexity of differential diagnosis is due to the lack of correlation between the degree of stenosis according to neuroimaging data and the severity of clinical manifestations. Spinal stenosis among 21 % of people may have an asymptomatic course. Spinal stenosis has to be differentiated from atherosclerosis of the vessels of the lower extremities, rheumatoid arthritis, piriformis syndrome, sacroiliitis, spondylitis/spondylodiscitis, amyotrophic lateral sclerosis, Guillain–Barré syndrome and other polyneuropathies. Isolated weakness should be of a particular concern in the clinical picture. Muscle hypotrophy, brisk tendon reflexes, the presence of pyramidal signs, muscle fasciculations, as well as patients’ complaints of simultaneous weakness in both the upper and lower extremities accompany them. We present and discuss three clinical cases of patients with a presumptive diagnosis of spinal stenosis. Two of them were held surgical treatment, which did not produce the expected result. Subsequently, it was found that the cause of progressive muscle weakness in the limbs was amyotrophic lateral sclerosis in two patients and the third one had Guillain–Barré syndrome, a form of acute demyelinating polyneuropathy.
椎管狭窄症是由于年龄相关变化引起的椎管中央、侧袋或椎间孔的病理性狭窄,包括椎间盘病理、小关节、韧带肥大、骨赘形成和弓破坏。在临床上,这种疾病可以表现为疼痛,以及麻木或手臂或腿部无力。由于神经影像学资料显示的狭窄程度与临床表现的严重程度之间缺乏相关性,导致了鉴别诊断的复杂性。21%的椎管狭窄患者可能无症状病程。椎管狭窄症必须与下肢血管动脉粥样硬化、类风湿性关节炎、梨状体综合征、骶髂炎、脊柱炎/椎间盘炎、肌萎缩性侧索硬化症、格林-巴罗综合征等多神经病变相鉴别。孤立性虚弱在临床表现中应引起特别关注。肌肉萎缩,肌腱反射快,锥体征象,肌肉束状,以及患者的主诉同时无力在上肢和下肢伴随。我们提出并讨论三个临床病例的患者推定诊断为椎管狭窄。其中两人接受了手术治疗,但没有达到预期的效果。随后,发现两例患者的进行性四肢肌肉无力的原因是肌萎缩性侧索硬化症,第三例患者患有格林-巴罗综合征,这是一种急性脱髓鞘性多神经病变。
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引用次数: 0
Jugular foramen meningeal melanocytoma 颈静脉孔脑膜黑色素细胞瘤
Pub Date : 2023-10-19 DOI: 10.17650/1683-3295-2023-25-3-111-118
I. O. Kugushev, T. Yu. Bezborodova, V. K. Poshataev, D. S. Kim, K. V. Shevchenko, R. A. Sultanov, V. V. Karnaukhov, S. V. Tanyashin, V. N. Shimansky
Meningeal melanocytoma is a pigmented tumor arising from leptomeningeal melanocytes and occurring with a of 1 case per 10 million people. The main method of diagnosing meningeal melanocytoma is contrast‑enhanced magnetic resonance imaging, however, it is quite difficult to distinguish it from other skull base tumors. We present a case of successful treatment of a patient with this rare pathology
脑膜黑素细胞瘤是一种由脑膜黑素细胞引起的色素瘤,每1000万人中发生1例。脑膜黑素细胞瘤的主要诊断方法是增强磁共振成像,但很难与其他颅底肿瘤区分开来。我们提出一例成功治疗的病人与这种罕见的病理
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引用次数: 0
Morphogenetic characteristics of glial tumors in adults per the WHO classifications of 2007, 2016, 2021. Changes in the classifications and their significance for clinical practice 成人神经胶质瘤的形态发生特征(2007年、2016年、2021年WHO分类)分类的变化及其对临床的意义
Pub Date : 2023-10-19 DOI: 10.17650/1683-3295-2023-25-3-135-148
V. V. Krylov, G. Yu. Evzikov, G. L. Kobyakov
The presented lecture is dedicated to analysis of morphogenetic characteristics of glial tumors in adults in the framework of the World Health Organization (WHO) classifications of 2007, 2016, 2021, changes in the classifications and their significance for clinical practice. This topic is important because the most difficult changes for neurosurgeons to understand in comparison of the WHO classifications of 2007, 2016 and 2021 involved sections on glial tumors and children’s tumors. The authors focus on increasing practical significance of genetic component in tumor characterization. The classification of 2007 was the last purely morphological classification of central nervous system tumors, it did not include genetic principles of tumor division in different groups. In the following years, knowledge on the significance of various mutations for prognosis of glial tumor progression and selection of optimal treatment based in genetic characteristics of the neoplasm has been actively accumulated. In the 2016 edition, morphological and genetic tumor characteristics were consolidated for the first time which was unquestionably a necessary step. Complex integrative analysis of glioma genomes has shown that genetic characteristics have higher prognostic value compared to the WHO Grade. In the classification of 2021, names of the tumors proposed in 2016 were changed, and practical significance of the genetic component in tumor characterization was increased. However, this can further complicate interpretation of histological diagnosis by practicing neurosurgeons. Implementation of the 2021 WHO classification in clinical practice assumes expansion of the spectrum of genetic diagnostic methods. The neurosurgical community should be ready to interpret morphogenetic results and select treatment tactics in tandem with oncologists based on genetic characteristics of the tumor.
本讲座旨在分析2007年、2016年、2021年世界卫生组织(WHO)分类框架下成人神经胶质肿瘤的形态发生特征、分类的变化及其对临床实践的意义。这一主题很重要,因为与2007年、2016年和2021年的世卫组织分类相比,神经外科医生最难理解的变化涉及神经胶质肿瘤和儿童肿瘤部分。作者的重点是提高遗传成分在肿瘤表征中的实际意义。2007年的分类是最后一个纯粹的中枢神经系统肿瘤形态学分类,它不包括肿瘤在不同群体中分裂的遗传原理。在接下来的几年里,关于各种突变对神经胶质肿瘤进展的预后和基于肿瘤遗传特征选择最佳治疗的重要性的知识得到了积极的积累。在2016年的版本中,首次整合了肿瘤的形态和遗传特征,这无疑是必要的一步。神经胶质瘤基因组的复杂综合分析表明,与WHO分级相比,遗传特征具有更高的预后价值。在2021年的分类中,对2016年提出的肿瘤名称进行了修改,增加了遗传成分在肿瘤表征中的实际意义。然而,这可能进一步使神经外科医生对组织学诊断的解释复杂化。在临床实践中实施世卫组织2021年分类需要扩大遗传诊断方法的范围。神经外科社区应该准备好解释形态发生结果,并根据肿瘤的遗传特征与肿瘤学家一起选择治疗策略。
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引用次数: 0
Basal forebrain: anatomy and clinical presentation of injury 基底前脑:损伤的解剖与临床表现
Pub Date : 2023-10-19 DOI: 10.17650/1683-3295-2023-25-3-126-134
R. E. Ishkinin, D. I. Pitskhelauri, A. E. Bykanov
The basal forebrain is a complex anatomic region with a lot of nuclei and fibers. Tumors or direct lesions of this area do not always manifest clinically despite it taking a part in behavior, emotion and cognition. A deep understanding of the anatomy of the gray matter and associative pathways passing through the basal forebrain allows us to take a different look at clinical manifestations in the preand postoperative period. Based on the literature review, we tried to describe the anatomical, phylogenetic and functional connections of the basal forebrain with surrounding regions and analyze what changes in clinical symptoms appear when it is locally damaged.
基底前脑是一个复杂的解剖区域,有大量的核和纤维。该区域的肿瘤或直接病变虽然参与行为、情绪和认知,但并不总是表现在临床。对通过基底前脑的灰质解剖学和相关通路的深入了解使我们能够从不同的角度看待术前和术后的临床表现。在文献综述的基础上,我们试图描述基底前脑与周围区域的解剖学、系统发育和功能联系,并分析其局部损伤时临床症状的变化。
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引用次数: 0
Third All-Russian Neurosurgical Forum 第三届全俄神经外科论坛
Pub Date : 2023-10-19 DOI: 10.17650/1683-3295-2023-25-3-149-151
D. D. Eliferov
.
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引用次数: 0
Ligamentum flavum ganglion cyst of the cervical spine: a rare cause of myelopathy. Clinical observation and literature review 颈椎黄韧带神经节囊肿:脊髓病的罕见病因。临床观察及文献复习
Pub Date : 2023-10-19 DOI: 10.17650/1683-3295-2023-25-3-88-92
I. V. Basankin, A. A. Gyulzatyan, S. B. Malakhov, V. G. Didenko, M. I. Tomina, I. E. Gritsaev
Juxtafacet cysts include both synovial cysts directly from the facet capsule and ganglion cysts arising from the ligamentum flavum. Ganglion cysts of the cervical spine are extremely rare benign masses. The inner surface of the capsule of ganglion cysts consists of fibroblasts and has no anatomical connection with the capsule of the facet joint. Magnetic resonance imaging is the method of choice for the diagnosis of ligamentum flavum cysts, with a hyperintense round mass on T2‑weighted images with clear margins and no perifocal edema. On T1‑weighted images, an isointense signal is noted, and with contrast enhancement, the cyst wall more often accumulates a contrast. The method of choice in the surgical treatment of cysts is their total removal with sparing bone resection of the posterior vertebral structures. The outcome of surgical treatment of these formations is good with no risk of recurrence.
关节突旁囊肿包括直接来自关节突囊的滑膜囊肿和起源于黄韧带的神经节囊肿。颈椎神经节囊肿是极为罕见的良性肿块。神经节囊肿包膜的内表面由成纤维细胞组成,与关节突关节包膜无解剖联系。磁共振成像是诊断黄韧带囊肿的首选方法,在T2加权图像上可见高强度圆形肿块,边缘清晰,无焦周水肿。在T1加权图像上,可以观察到等强信号,并且随着对比度增强,囊肿壁更容易积聚对比度。选择囊肿的手术治疗方法是将囊肿全部切除并保留后部椎体结构。手术治疗的结果是良好的,没有复发的风险。
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引用次数: 0
Thalamotomy with focused ultrasound in the treatment of musician’s dystonia 聚焦超声丘脑切开术治疗音乐家肌张力障碍
Pub Date : 2023-10-19 DOI: 10.17650/1683-3295-2023-25-3-93-99
V. M. Dzhafarov, A. I. Kholyavin, M. E. Amelin, M. Yu. Dzhafarova, K. S. Zolotareva, I. V. Senko
Background. Approximately from 0.5 to 8 % professional musicians may suffer from focal dystonia. Stereotactic surgery is option if conservative therapy is failed. Thalamotomy has been reported in limited series in the world literature. Aim. To demonstrate a clinical case of thalamotomy with focused ultrasound in a professional guitarist with focal dystonia of the hand. M ate ri als a nd me t h o d s. A 40‑year‑old patient suffered from spasms of the fingers while playing the guitar since 2009. Patient lost professional skills and changed his activities due to progression and severity of disease. He visited our clinic for surgical treatment, stereotactic ventro‑oral thalamotomy by transcranial focused ultrasound was considered. Results. Thalamotomy provided complete reduction of dystonia without complications. On the 2nd day after the procedure, the patient discharged. In a week mild dysarthria was noticed, which did not affect daily activities and completely regressed within a month. A month later, the patient was able to return to concert performance. The follow‑up period was 6 months with no symptoms of the disease. Conclusion. Successful clinical case of focused ultrasound thalamotomy in patient with musician’s dystonia is presented.
背景。大约有0.5%到8%的专业音乐家可能患有局灶性肌张力障碍。如果保守治疗失败,立体定向手术是一种选择。丘脑切开术在世界文献中有有限的系列报道。的目标。目的:探讨一个专业吉他手局灶性肌张力障碍的丘脑切开术的临床病例。从2009年开始,a某(40岁)在弹吉他时出现了手指痉挛。由于病情的进展和严重程度,患者丧失了专业技能并改变了活动方式。他到我诊所接受手术治疗,考虑经颅聚焦超声立体定向腹口丘脑切除术。结果。丘脑切开术可完全减轻肌张力障碍,无并发症。术后第2天,患者出院。一周后发现轻度构音障碍,不影响日常活动,并在一个月内完全消退。一个月后,病人又能参加音乐会了。随访6个月,无疾病症状。结论。本文报道聚焦超声丘脑切开术治疗音乐家肌张力障碍的成功临床病例。
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引用次数: 0
Resection of giant sigmoid cancer metastasis in the skull bone with extra-, intracranial distribution 颅内外分布的颅骨巨大乙状结肠癌转移瘤切除术
Pub Date : 2023-10-18 DOI: 10.17650/1683-3295-2023-25-3-78-87
N. E. Voinov, A. Yu. Ulitin, P. V. Lavrovsky, M. V. Dikonenko, B. I. Safarov, S. S. Sklyar, D. A. Sitovskaya, A. S. Nechaeva, A. E. Vershinin, I. A. Sokolov
The most common secondary target organs in patients with colorectal cancer are the liver and lungs. Cranial metastases from sigmoid colon cancer are rare. Giant cranial metastases are currently diagnosed in exceptional cases. The article presents a clinical case of a secondary extra‑intracranial lesion with a stable primary tumor focus in the sigmoid colon in a young patient with a high functional status.
结直肠癌患者最常见的次要靶器官是肝和肺。乙状结肠肿瘤的颅内转移是罕见的。巨大的头颅转移瘤目前在特殊情况下才被诊断出来。这篇文章提出了一个临床病例的继发性颅内外病变与稳定的原发肿瘤病灶在乙状结肠在一个年轻的病人高功能状态。
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引用次数: 0
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Неврология и нейрохирургия. Восточная Европа
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