Flavonoids are a group of phytochemical compounds commonly found in plants. Jatropha curcas L. And Jatropha gossypiifolia L. Are plants belonging to the same family, Euphorbiaceae. Both of these plants have significant potential, especially in health. This research aims to determine the comparison of total flavonoid levels in methanol extracts of Physic Nut (Jatropha curcas L.) and Cotton-Leaf Physic Nut (Jatropha gossypiifolia L.) leavs using U-Vis spectrophotometry method. This research utilizes both qualitative and quantitative analysis methods. The qualitative analysis involves phytocemical screening and Thin-Layer Chromatography analysis using an eluent of n-Hexane ethyl acetate with a ratio of (8:2). The quantitative analysis in this research utilized the UV-Vis spectrofotometry method at a wavelength of 435 nm with quercetin as the standard comparator. The results indicate that the average total flavonoid content in 100 mg of methanol extract from Physic Nut (Jatropha curcas L.) leaves is 5,75% w/v. Meanwhile, in the methanol extract from Cotton-Leaf Physic Nut (Jatropha gossypiifolia L.) leaves, it is 7,20% w/v. Based on Independent Sample T-test statistical analysis, the total flavonoid content in the methanol extract from Cotton-Leaf Physic Nut leaves is significantly higher than that in the methanol extract from Physic Nut Leaves, indieating a significant difference in the average values of two samples (p-value0,05).
{"title":"Perbandingan Kadar Flavonoid Total Jarak Pagar (Jatropha curcas L.) dan Jarak Merah (Jatropha gossypiifolia L.)","authors":"Hamsidar Hasan, Faramita Hiola, Fika Nuzul Ramadhani, Mahdalena Sy. Pakaya, Rahmatiya Imran Tululi","doi":"10.37311/jsscr.v5i3.23896","DOIUrl":"https://doi.org/10.37311/jsscr.v5i3.23896","url":null,"abstract":"Flavonoids are a group of phytochemical compounds commonly found in plants. Jatropha curcas L. And Jatropha gossypiifolia L. Are plants belonging to the same family, Euphorbiaceae. Both of these plants have significant potential, especially in health. This research aims to determine the comparison of total flavonoid levels in methanol extracts of Physic Nut (Jatropha curcas L.) and Cotton-Leaf Physic Nut (Jatropha gossypiifolia L.) leavs using U-Vis spectrophotometry method. This research utilizes both qualitative and quantitative analysis methods. The qualitative analysis involves phytocemical screening and Thin-Layer Chromatography analysis using an eluent of n-Hexane ethyl acetate with a ratio of (8:2). The quantitative analysis in this research utilized the UV-Vis spectrofotometry method at a wavelength of 435 nm with quercetin as the standard comparator. The results indicate that the average total flavonoid content in 100 mg of methanol extract from Physic Nut (Jatropha curcas L.) leaves is 5,75% w/v. Meanwhile, in the methanol extract from Cotton-Leaf Physic Nut (Jatropha gossypiifolia L.) leaves, it is 7,20% w/v. Based on Independent Sample T-test statistical analysis, the total flavonoid content in the methanol extract from Cotton-Leaf Physic Nut leaves is significantly higher than that in the methanol extract from Physic Nut Leaves, indieating a significant difference in the average values of two samples (p-value0,05).","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"66 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140224031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Healthcare services are one of the factors influencing the medication adherence of elderly patients. Therefore, in order to enhance the medication adherence of elderly patients, it is essential to understand the healthcare services required by the elderly, both from healthcare professionals and the healthcare system. This research aims to identify the necessary healthcare services for the elderly to improve their adherence. The method employed is in-depth interviews using validated interview guidelines, followed by analysis through thematic analysis. A total of 12 elderly patients suffering from diabetes mellitus were involved in this study, ranging in age from 56 to 70 years. The forms of healthcare services needed by these elderly patients include insurance-covered treatment costs with an easy and practical system, information about medications delivered by experts, the presence of methods or tools for medication reminder, healthcare professionals who understand the elderly, education about medications and diseases, as well as specialized facilities to obtain medications. This study is a qualitative research effort, with the hope that further research can be conducted to serve as a foundation for both central and regional governments in formulating policies related to the healthcare services required by the elderly.
{"title":"Identifikasi Layanan Kesehatan yang dibutuhkan Pasien Lansia untuk Menunjang Kepatuhan Minum Obat","authors":"A.Takdir Makkulawu, Multiani S. Latif","doi":"10.37311/jsscr.v6i1.24599","DOIUrl":"https://doi.org/10.37311/jsscr.v6i1.24599","url":null,"abstract":"Healthcare services are one of the factors influencing the medication adherence of elderly patients. Therefore, in order to enhance the medication adherence of elderly patients, it is essential to understand the healthcare services required by the elderly, both from healthcare professionals and the healthcare system. This research aims to identify the necessary healthcare services for the elderly to improve their adherence. The method employed is in-depth interviews using validated interview guidelines, followed by analysis through thematic analysis. A total of 12 elderly patients suffering from diabetes mellitus were involved in this study, ranging in age from 56 to 70 years. The forms of healthcare services needed by these elderly patients include insurance-covered treatment costs with an easy and practical system, information about medications delivered by experts, the presence of methods or tools for medication reminder, healthcare professionals who understand the elderly, education about medications and diseases, as well as specialized facilities to obtain medications. This study is a qualitative research effort, with the hope that further research can be conducted to serve as a foundation for both central and regional governments in formulating policies related to the healthcare services required by the elderly.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"47 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140429387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Endophytic fungi live in their host tissues, so that endophytic fungi can produce secondary metabolites that are similar to their hosts as well. In this case, the use of endophytic fungi can reduce the exploitation of seagrass populations (Thalassia hemprichii) in Tomini Bay. This study aims to examine the effectiveness of the secondary metabolite fraction of the endophytic seagrass fungus (Thalassia hemprichii) from Tomini Bay against acne-causing bacteria. The test method used is disc diffusion method (Kirby Bauer), by measuring the inhibition zones of the ethanol fraction, ethyl acetate fraction, and the N-hexan fraction of the secondary metabolite fraction of endophytic fungi against acne-causing bacteria. The liquid-liquid partition results of the secondary metabolites of seagrass endophytic fungi from the Tomini Bay area were the N-Hexan fraction of 3.06 grams, the Chloroform fraction of 2.90 grams, and the Ethyl Acetate fraction of 1.53 grams. While the effectiveness test of the N-Hexan, Chloroform, and Ethyl Acetate fractions of secondary metabolites of endophytic seagrass microbes from the Tomini Bay area showed that the N-Hexan fraction at a concentration of 75% had greater inhibition on each of the acne-causing bacteria, namely Propionibacterium acne 17 .33 mm (strong category), Staphylococcus aureus 17.86 mm (strong category), and Staphylococcus epidermidis 16.01 mm (strong category).
{"title":"Efektivitas Fraksi Metabolit Sekunder Jamur Endofit Lamun (Thalassia hemprichii) dari Kawasan Teluk Tomini Sebagai Antibakteri Jerawat","authors":"Mahdalena Sy. Pakaya, Fika Nuzul Ramadhani, Moh. Ridwan Ente","doi":"10.37311/jsscr.v6i1.21457","DOIUrl":"https://doi.org/10.37311/jsscr.v6i1.21457","url":null,"abstract":"Endophytic fungi live in their host tissues, so that endophytic fungi can produce secondary metabolites that are similar to their hosts as well. In this case, the use of endophytic fungi can reduce the exploitation of seagrass populations (Thalassia hemprichii) in Tomini Bay. This study aims to examine the effectiveness of the secondary metabolite fraction of the endophytic seagrass fungus (Thalassia hemprichii) from Tomini Bay against acne-causing bacteria. The test method used is disc diffusion method (Kirby Bauer), by measuring the inhibition zones of the ethanol fraction, ethyl acetate fraction, and the N-hexan fraction of the secondary metabolite fraction of endophytic fungi against acne-causing bacteria. The liquid-liquid partition results of the secondary metabolites of seagrass endophytic fungi from the Tomini Bay area were the N-Hexan fraction of 3.06 grams, the Chloroform fraction of 2.90 grams, and the Ethyl Acetate fraction of 1.53 grams. While the effectiveness test of the N-Hexan, Chloroform, and Ethyl Acetate fractions of secondary metabolites of endophytic seagrass microbes from the Tomini Bay area showed that the N-Hexan fraction at a concentration of 75% had greater inhibition on each of the acne-causing bacteria, namely Propionibacterium acne 17 .33 mm (strong category), Staphylococcus aureus 17.86 mm (strong category), and Staphylococcus epidermidis 16.01 mm (strong category).","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"28 31","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140450074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mangkokan leaves (Nothopanax scutellarium) are one of the ornamental plants in the yard. One of its benefits is that it is antibacterial. The use of antibacterials has been widely used to inhibit the growth of bacteria, but antibiotic resistance against bacteria continues to increase. The purpose of this review article is to examine the extent to which mangkokan leaves (Nothopanax scutellarium) have been tested as antibacterial and to examine secondary metabolites that have an antibacterial role. This research took the form of an article search carried out based on inclusion and exclusion criteria. The inclusion criteria used were articles published within a 10 years span. Based on article search results, mangkokan leaves (Nothopanax scutellarium) have been proven to be able to inhibit the growth of several bacteria including Staphylococcus aureus, Eschericia coli, Staphylococcus epidermidis, Pseudomonas aeruginosa, Propionobacterium acne, Salmonella gastroenterit, Lactobacilus rhamnosus and Bacillus subtilis. Secondary metabolites that have an active role as antibacterials are tannins, flavonoids and saponins.
{"title":"Review Artikel : Aktivitas Antibakteri Daun Mangkokan (Nothopanax scutellarium)","authors":"Milla Oktaviani, Siskha Al Zahra","doi":"10.37311/jsscr.v5i3.24321","DOIUrl":"https://doi.org/10.37311/jsscr.v5i3.24321","url":null,"abstract":"Mangkokan leaves (Nothopanax scutellarium) are one of the ornamental plants in the yard. One of its benefits is that it is antibacterial. The use of antibacterials has been widely used to inhibit the growth of bacteria, but antibiotic resistance against bacteria continues to increase. The purpose of this review article is to examine the extent to which mangkokan leaves (Nothopanax scutellarium) have been tested as antibacterial and to examine secondary metabolites that have an antibacterial role. This research took the form of an article search carried out based on inclusion and exclusion criteria. The inclusion criteria used were articles published within a 10 years span. Based on article search results, mangkokan leaves (Nothopanax scutellarium) have been proven to be able to inhibit the growth of several bacteria including Staphylococcus aureus, Eschericia coli, Staphylococcus epidermidis, Pseudomonas aeruginosa, Propionobacterium acne, Salmonella gastroenterit, Lactobacilus rhamnosus and Bacillus subtilis. Secondary metabolites that have an active role as antibacterials are tannins, flavonoids and saponins.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"6 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140460945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dandruff is a health problem that is often experienced by most people because it can reduce self-confidence. The aim of this research is to determine the extract of Chinese ketepeng leaves (Cassia alata L) as an anti-dandruff shampoo preparation and to determine the activity of the shampoo against Pityrosporum ovale and Candida albicans fungi using laboratory experimental methods. This research is divided into three concentration variations, namely 10% - 15% 20% and two supporting controls, namely control (-) without extract and control (+), namely ketomed shampoo. Results: The results of the research for the inhibitory power of the fungus Pityrosporum ovale without extract (-) have a value of 4.43 mm at a concentration of 10% have an inhibition zone of 17.23 mm at a concentration of 15% have an inhibitory zone value of 18.67 mm at a concentration of 20% have the value of the inhibition zone is 19.66 mm in the control (+) which has a value of 20.87 mm. In Candida albicans without extract (-) it has a value of 2.33 mm at a concentration of 10% it has an inhibition zone value of 16.44 mm at a concentration of 15% it has an inhibition zone value of 17.76 mm at a concentration of 20% it has an inhibition zone value of 19.37 mm at control (+) has a value of 20.54 mm. Chinese ketepeng (Cassia alata L.) leaf extract can be used as an anti-dandruff shampoo, based on the results of the preparation evaluation it was found that the formula with a concentration of 15% meets the characteristics of a good shampoo, and the flavonoid compound content in Chinese Ketapang (Cassia alata L.) leaf extract is 15% has a high zone of inhibition against P. ovale and C. albicans fungi. So it can be concluded that the best formula obtained in this study was at an extract concentration of 15%.
{"title":"Uji Aktivitas Sediaan Sampo Antiketombe Ekstrak Daun Ketepeng Cina (Cassia alata L) Terhadap Jamur Pityrosporum ovale","authors":"A. Suryani, Eneng Ikrimah Rohwah","doi":"10.37311/jsscr.v5i3.24310","DOIUrl":"https://doi.org/10.37311/jsscr.v5i3.24310","url":null,"abstract":"Dandruff is a health problem that is often experienced by most people because it can reduce self-confidence. The aim of this research is to determine the extract of Chinese ketepeng leaves (Cassia alata L) as an anti-dandruff shampoo preparation and to determine the activity of the shampoo against Pityrosporum ovale and Candida albicans fungi using laboratory experimental methods. This research is divided into three concentration variations, namely 10% - 15% 20% and two supporting controls, namely control (-) without extract and control (+), namely ketomed shampoo. Results: The results of the research for the inhibitory power of the fungus Pityrosporum ovale without extract (-) have a value of 4.43 mm at a concentration of 10% have an inhibition zone of 17.23 mm at a concentration of 15% have an inhibitory zone value of 18.67 mm at a concentration of 20% have the value of the inhibition zone is 19.66 mm in the control (+) which has a value of 20.87 mm. In Candida albicans without extract (-) it has a value of 2.33 mm at a concentration of 10% it has an inhibition zone value of 16.44 mm at a concentration of 15% it has an inhibition zone value of 17.76 mm at a concentration of 20% it has an inhibition zone value of 19.37 mm at control (+) has a value of 20.54 mm. Chinese ketepeng (Cassia alata L.) leaf extract can be used as an anti-dandruff shampoo, based on the results of the preparation evaluation it was found that the formula with a concentration of 15% meets the characteristics of a good shampoo, and the flavonoid compound content in Chinese Ketapang (Cassia alata L.) leaf extract is 15% has a high zone of inhibition against P. ovale and C. albicans fungi. So it can be concluded that the best formula obtained in this study was at an extract concentration of 15%.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"41 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140461116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Barely used by the community, papaya seeds (Carica papaya L.) astonishingly contain flavonoid compounds that can be turned into antioxidants to counter free radicals. However, the amount of flavonoids in papaya depends on where it grows. Types of papaya (Carica papaya L.) that are often grown and consumed by the Gorontalo community are Bangkok and California varieties. Therefore, this study aims to analyze the levels of flavonoid compounds in papaya seeds (Carica papaya L.) of Bangkok and California varieties grown in Gorontalo province using UV-Vis spectrophotometry instruments. Qualitative analysis in this study is conducted through phytochemical screening methods. Meanwhile, the quantitavie analysis uses the UV-Vis spectrophotometry method at 419 nm wavelength with quercetin’s standard comparison solution. The result discloses that highest average flavonoid compound of papaya seed extract (Carica papaya L.) is in Bangkok variety with 10,197% w/v, followed by the California variety with 3,475% w/v. Bangkok and California papaya seed extracts have met validation standards with correlation coefficient values of 0,9991, regression function coefficient values (Vx0) 0f 2,1%, %retrieval values of Bangkok papaya seed extract is 100,05% and California is 101, 29%, RSD% values for Bangkok papaya seed ethanol extract is 1,775% and California is 1,348%.
{"title":"Perbandingan Flavonoid Total pada Ekstrak Biji Pepaya (Carica papaya L.) Varietas Bangkok dan California","authors":"M. Taupik, A.Takdir Makkulawu, Fahrul Ilham, Arini Saman","doi":"10.37311/jsscr.v5i3.21871","DOIUrl":"https://doi.org/10.37311/jsscr.v5i3.21871","url":null,"abstract":"Barely used by the community, papaya seeds (Carica papaya L.) astonishingly contain flavonoid compounds that can be turned into antioxidants to counter free radicals. However, the amount of flavonoids in papaya depends on where it grows. Types of papaya (Carica papaya L.) that are often grown and consumed by the Gorontalo community are Bangkok and California varieties. Therefore, this study aims to analyze the levels of flavonoid compounds in papaya seeds (Carica papaya L.) of Bangkok and California varieties grown in Gorontalo province using UV-Vis spectrophotometry instruments. Qualitative analysis in this study is conducted through phytochemical screening methods. Meanwhile, the quantitavie analysis uses the UV-Vis spectrophotometry method at 419 nm wavelength with quercetin’s standard comparison solution. The result discloses that highest average flavonoid compound of papaya seed extract (Carica papaya L.) is in Bangkok variety with 10,197% w/v, followed by the California variety with 3,475% w/v. Bangkok and California papaya seed extracts have met validation standards with correlation coefficient values of 0,9991, regression function coefficient values (Vx0) 0f 2,1%, %retrieval values of Bangkok papaya seed extract is 100,05% and California is 101, 29%, RSD% values for Bangkok papaya seed ethanol extract is 1,775% and California is 1,348%.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"30 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140482153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutmeg is considered an important ingredient of various industrial applications ranging from food to cosmetics. The pharmaceutical product is also important for its antioxidant and antimicrobial properties. Further research is needed to isolate and identify the bioactive compounds of Myristica fragrans. The aim of this research was to isolate and determine the antioxidant activity of the essential oil of nutmeg flesh (Myristica fragrans). The sample used was nutmeg flesh (Myristica fragrans) taken from Ternate Island, North Maluku. The essential oil of nutmeg flesh was isolated using water vapor distillation and the antioxidant activity was tested using the DPPH method. All data are presented as mean ± standard deviation (SD) and were carried out in triplicate. The results of the research showed that the isolation of nutmeg essential oil obtained with a yield of 0,32%. Organoleptically, the essential oil of nutmeg flesh obtained from the steam distillation process has quality that meets SNI, in the form of a clear to rusty liquid and has a distinctive odor. Phytochemical tests obtained that the essential oil of nutmeg flesh contains alkaloids, flavonoids and steroids, and does not contain polyphenols and saponins. The concentration of essential oil increases, the absorption value and percent inhibition increase so that an average IC50 value of 49,34 ppm is obtained. The essential oil of nutmeg flesh by steam distillation obtained a yield of 0,32% and has antioxidant activity which is classified as a strong antioxidant
{"title":"Isolasi dan Uji Aktivitas Antioksidan Minyak Atsiri Daging Buah Pala (Myristica fragrans)","authors":"Muh Nasir, Eri Marwati","doi":"10.37311/jsscr.v5i3.24109","DOIUrl":"https://doi.org/10.37311/jsscr.v5i3.24109","url":null,"abstract":"Nutmeg is considered an important ingredient of various industrial applications ranging from food to cosmetics. The pharmaceutical product is also important for its antioxidant and antimicrobial properties. Further research is needed to isolate and identify the bioactive compounds of Myristica fragrans. The aim of this research was to isolate and determine the antioxidant activity of the essential oil of nutmeg flesh (Myristica fragrans). The sample used was nutmeg flesh (Myristica fragrans) taken from Ternate Island, North Maluku. The essential oil of nutmeg flesh was isolated using water vapor distillation and the antioxidant activity was tested using the DPPH method. All data are presented as mean ± standard deviation (SD) and were carried out in triplicate. The results of the research showed that the isolation of nutmeg essential oil obtained with a yield of 0,32%. Organoleptically, the essential oil of nutmeg flesh obtained from the steam distillation process has quality that meets SNI, in the form of a clear to rusty liquid and has a distinctive odor. Phytochemical tests obtained that the essential oil of nutmeg flesh contains alkaloids, flavonoids and steroids, and does not contain polyphenols and saponins. The concentration of essential oil increases, the absorption value and percent inhibition increase so that an average IC50 value of 49,34 ppm is obtained. The essential oil of nutmeg flesh by steam distillation obtained a yield of 0,32% and has antioxidant activity which is classified as a strong antioxidant","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"38 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140494304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sodium benzoate is the sodium salt of benzoic acid which is often used in food ingridiends, for example in tomato sauce. In foodstuffs, sodium benzoate will break down into its active from or benzoate acid. However, the use of sodium benzoate should not exceed 0,1% in food ingedients. Meanwhile, Rhodamin B is a textle and pape day where this substance is very harmful if inhald, in contact with skin. In eyes and swallowed. The research aimed to determine the amount of sodium benzoat and rhodamin B in tomato sauce circulating in Gorontalo City. The samples of tomato sauce were obtained randomly from three markets in Gorontalo City regardless of its conditions whether those who did not have circulation permit or did not have obvious composition and BPOM permit. The method for determinating sodium benzoate and rhodamine B levels was carried out using UV-Vis spectrophotometry. The results obtained were sodium benzoate preservative levels in the three samples were 0,9363 g/kg in sample A, 1,5469 g/kg in sample B, and 1,8725 g/kg in sample C. Meanwhile, the rhodamine B levels in the three samples were 0,7515 in sample A, 1,5015 in sample B, and 1,5833 in sample C. Based on the results of this concentration calculation, it is observable that all samples have exceeded the threshold for using sodium benzoate and rhodamine B.
苯甲酸钠是苯甲酸的钠盐，常用于食品添加剂，例如番茄酱。在食品中，苯甲酸钠会分解成其活性成分或苯甲酸。不过，苯甲酸钠在食品中的用量不应超过 0.1%。同时，罗丹明 B 是一种纺织品和涂料，如果吸入、接触皮肤或吞咽，都会对人体造成严重危害。眼睛和吞咽。这项研究旨在确定戈伦塔洛市番茄酱中苯甲酸钠和罗丹明 B 的含量。番茄酱样品从哥伦塔罗市的三个市场随机获得，无论其条件如何，是没有流通许可证还是没有明显的成分和 BPOM 许可证。苯甲酸钠和罗丹明 B 含量的测定方法采用紫外可见分光光度法。结果显示，三个样品中苯甲酸钠防腐剂的含量分别为：A 样品 0.9363 克/千克，B 样品 1.5469 克/千克，C 样品 1.8725 克/千克；罗丹明 B 的含量分别为：A 样品 0.7515 克/千克，B 样品 1.5015 克/千克，C 样品 1.5833 克/千克。
{"title":"Analisis Natrium Benzoat dan Rhodamin B Pada Saos Tomat Pasaran yang Beredar di Kota Gorontalo","authors":"Ishak Isa, M. Taupik, Lilis Lebie, Fahrul Ilham","doi":"10.37311/jsscr.v6i1.23386","DOIUrl":"https://doi.org/10.37311/jsscr.v6i1.23386","url":null,"abstract":"Sodium benzoate is the sodium salt of benzoic acid which is often used in food ingridiends, for example in tomato sauce. In foodstuffs, sodium benzoate will break down into its active from or benzoate acid. However, the use of sodium benzoate should not exceed 0,1% in food ingedients. Meanwhile, Rhodamin B is a textle and pape day where this substance is very harmful if inhald, in contact with skin. In eyes and swallowed. The research aimed to determine the amount of sodium benzoat and rhodamin B in tomato sauce circulating in Gorontalo City. The samples of tomato sauce were obtained randomly from three markets in Gorontalo City regardless of its conditions whether those who did not have circulation permit or did not have obvious composition and BPOM permit. The method for determinating sodium benzoate and rhodamine B levels was carried out using UV-Vis spectrophotometry. The results obtained were sodium benzoate preservative levels in the three samples were 0,9363 g/kg in sample A, 1,5469 g/kg in sample B, and 1,8725 g/kg in sample C. Meanwhile, the rhodamine B levels in the three samples were 0,7515 in sample A, 1,5015 in sample B, and 1,5833 in sample C. Based on the results of this concentration calculation, it is observable that all samples have exceeded the threshold for using sodium benzoate and rhodamine B.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"48 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140497469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sickle senna (Senna tora (L.) Roxb.) is a wild plant that is used by the community as a traditional medicine to treat diarrhea and intestinal worms. In the development of plants as traditional medicines, it is necessary to standardize the quality of plant materials to ensure their quality, stability, and safety. This study aims to determine the standadization of extracts both specifically and non-specifically and to determine the level of falvonoids in the fraction of sickle senna (Senna tora (L.) Roxb.) leaves. This study applies a phytochemical screening test, specific parameter test, non-specific parameter test, and flavonoid levels determination. The result of phytochemical screening shows that the fraction containing flavonoid compounds is 70% ethanol fraction. The results of standardization for specific parameter show the organoleptic ethanol fraction of 70% is in the form of semi-solid/viscous, black color and distinctive smell, with water soluble extract content is 19.08%, and ethanol soluble extract content is 23.35%. the standardization result for non-specific parameter shows that the total ash content is 1.76%, the acid insoluble ash content is 2.890%, drying shrinkage is 4.96%, and water content is 18.80%. meanwhile, metal and microbial contamination show no contamination in the 70% ethanol fraction. The result for the analysis of the flavonoid content of the 70% ethanol fraction. The result for the analysis of the flavonoid content of the 70% ethanol fraction of sickle senna leaves is carried out at a wavelength of 438.36 nm with an absorbance value of 0.0154. The total flavonoid level is calculated by the standard linear equation of quarcetin, which is y=0.0648x + (-0.0232) with a correlation coefficient (r2) = 0,9948 and a total flavonoid content of 4.713%
{"title":"Standardisasi dan Pengukuran Kadar Flavonoid Daun Ketepeng Kecil (Senna tora (L.) Roxb.) Menggunakan Metode Spektrofotometri UV-Vis","authors":"Mahdalena Sy. Pakaya, Ishak Isa, M. Taupik, Mohamad Aprianto Paneo, Aldawaty I. Ahyar","doi":"10.37311/jsscr.v6i1.15926","DOIUrl":"https://doi.org/10.37311/jsscr.v6i1.15926","url":null,"abstract":"Sickle senna (Senna tora (L.) Roxb.) is a wild plant that is used by the community as a traditional medicine to treat diarrhea and intestinal worms. In the development of plants as traditional medicines, it is necessary to standardize the quality of plant materials to ensure their quality, stability, and safety. This study aims to determine the standadization of extracts both specifically and non-specifically and to determine the level of falvonoids in the fraction of sickle senna (Senna tora (L.) Roxb.) leaves. This study applies a phytochemical screening test, specific parameter test, non-specific parameter test, and flavonoid levels determination. The result of phytochemical screening shows that the fraction containing flavonoid compounds is 70% ethanol fraction. The results of standardization for specific parameter show the organoleptic ethanol fraction of 70% is in the form of semi-solid/viscous, black color and distinctive smell, with water soluble extract content is 19.08%, and ethanol soluble extract content is 23.35%. the standardization result for non-specific parameter shows that the total ash content is 1.76%, the acid insoluble ash content is 2.890%, drying shrinkage is 4.96%, and water content is 18.80%. meanwhile, metal and microbial contamination show no contamination in the 70% ethanol fraction. The result for the analysis of the flavonoid content of the 70% ethanol fraction. The result for the analysis of the flavonoid content of the 70% ethanol fraction of sickle senna leaves is carried out at a wavelength of 438.36 nm with an absorbance value of 0.0154. The total flavonoid level is calculated by the standard linear equation of quarcetin, which is y=0.0648x + (-0.0232) with a correlation coefficient (r2) = 0,9948 and a total flavonoid content of 4.713%","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140501300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dyspepsia is an upper gastrointestinal symptom complex that has symptoms of fulllness after eating, early satiety, or epigastric pain of burning without any sturctural cause. The research aims to determine the suitability of drug therapy based on the right patient, the right drug, and the right dose in the emergency room at dr. Zainal Umar Sidiki Regional Public Hospital, North Gorontalo Regency. This research is descriptive research with retrospective data collection. The data used were obtained from medical records of patients in the ER, with 215 patients whose paatient characteristics were processed using the Microsoft Excel program. The results showed that most dyspepsia patients were female, namely 124 (58%), the age range 50-60 years was 74 (34%). The most widely used therapy is combination therapy 154 (72%). The largest variation in the number of single drug uses Inj. Omeprazole amounted to 34 (16%), and a combination of two types of drugs that are widely used, namely Inj. Omeprazole with Inj. Ondansetron has a total of 36 (17%) and a combination of three types of drugs that are widely use, including PPIs, cytoprotectants, and prokinetics, totaling 23 (11%). The rationality of the right patient treatment was 53,48%, the right medicstion was 78%, and the right dose was 100%. In conclusionm the appropriateness of therapy based on the right patient was 53,48%, the right drug was 78%, and the right dose was 100%.
{"title":"Profil Kesesuaian Terapi Obat Pada Pasien Dispepsia di Ruangan IGD RSUD dr. Zainal Umar Sidiki","authors":"T. S. Tuloli, Nur Rasdianah, W. Abdulkadir, Wiwit Zuriati Uno, Silvana Pandju","doi":"10.37311/jsscr.v6i1.23822","DOIUrl":"https://doi.org/10.37311/jsscr.v6i1.23822","url":null,"abstract":"Dyspepsia is an upper gastrointestinal symptom complex that has symptoms of fulllness after eating, early satiety, or epigastric pain of burning without any sturctural cause. The research aims to determine the suitability of drug therapy based on the right patient, the right drug, and the right dose in the emergency room at dr. Zainal Umar Sidiki Regional Public Hospital, North Gorontalo Regency. This research is descriptive research with retrospective data collection. The data used were obtained from medical records of patients in the ER, with 215 patients whose paatient characteristics were processed using the Microsoft Excel program. The results showed that most dyspepsia patients were female, namely 124 (58%), the age range 50-60 years was 74 (34%). The most widely used therapy is combination therapy 154 (72%). The largest variation in the number of single drug uses Inj. Omeprazole amounted to 34 (16%), and a combination of two types of drugs that are widely used, namely Inj. Omeprazole with Inj. Ondansetron has a total of 36 (17%) and a combination of three types of drugs that are widely use, including PPIs, cytoprotectants, and prokinetics, totaling 23 (11%). The rationality of the right patient treatment was 53,48%, the right medicstion was 78%, and the right dose was 100%. In conclusionm the appropriateness of therapy based on the right patient was 53,48%, the right drug was 78%, and the right dose was 100%.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"82 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140501235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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