M.Si.Apt Mahdalena Sy. Pakaya, Nurain Thomas, P. Idris
Clove (Syzygium aromaticumL.) leaf has efficacy as repellent because it contains terpenoid eugenol. This study aimed to determine how the effectiveness of clove leaf extract patch dosage as a mosquito repellent. This research was started with extraction using maceration method with 96% ethanol solvent. Furthermore, making the dosage of patch of clove leaf extract using matrix method with variation of the clove leaf extract concentration. Then, the effectiveness of mosquito repellent patch was tested by using rabbit that divided into 5 treatment groups namely K- (base patch), K+ (mosquito repellent patch), 3 groups of clove leaf extract patch with variation of concentration of F1a (concentration of 1%), F1b (concentration of 3%), and F1c (concentration of 5%). Each group was attached to the clothes of the rabbit and put into the experimental box that had been put by mosquito as many as 20 tails. Based on result of ANNOVA statistic test showed that clove (Syzygium aromaticumL.) leaf patch dosage against the rabbit gave a significant effect against mosquito repellent, where at 5% concentration of clove leaf extract could give mosquito repellent efficacy better than concentration 1% and 3%.
{"title":"UJI EFEKTIVITAS SEDIAAN PATCH EKSTRAK DAUN CENGKEH (Syzygium aromaticum) SEBAGAI REPELLENT NYAMUK","authors":"M.Si.Apt Mahdalena Sy. Pakaya, Nurain Thomas, P. Idris","doi":"10.3731/jsscr.v1i1.2201","DOIUrl":"https://doi.org/10.3731/jsscr.v1i1.2201","url":null,"abstract":"Clove (Syzygium aromaticumL.) leaf has efficacy as repellent because it contains terpenoid eugenol. This study aimed to determine how the effectiveness of clove leaf extract patch dosage as a mosquito repellent. This research was started with extraction using maceration method with 96% ethanol solvent. Furthermore, making the dosage of patch of clove leaf extract using matrix method with variation of the clove leaf extract concentration. Then, the effectiveness of mosquito repellent patch was tested by using rabbit that divided into 5 treatment groups namely K- (base patch), K+ (mosquito repellent patch), 3 groups of clove leaf extract patch with variation of concentration of F1a (concentration of 1%), F1b (concentration of 3%), and F1c (concentration of 5%). Each group was attached to the clothes of the rabbit and put into the experimental box that had been put by mosquito as many as 20 tails. Based on result of ANNOVA statistic test showed that clove (Syzygium aromaticumL.) leaf patch dosage against the rabbit gave a significant effect against mosquito repellent, where at 5% concentration of clove leaf extract could give mosquito repellent efficacy better than concentration 1% and 3%.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"07 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127291083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M.Sc Mohammad Adam Mustapa, M. Taupik, L. AdityaRamadhan
The Snake Fruit (Salacca zalacca (Gaertn.) Voss) skin is considered as a waste, but there are a small number of people who use this fruit skin as an medicine. A compound that plays a role in snake fruit skin for the treatment is flavonoid. The purpose of this study was to determine the level of flavonoid contained in the extract of snake fruit skin. The method used to determine the amount of flavonoid compound contained in it is the UV-Vis Spectrophotometry method. The result of reading the absorbance value of each snake fruit fraction obtained from the methanol fraction was 0.568 and ethyl acetate fraction of 0.319, which were then calculated by using the quercetin linear equation standard, y = 0.0608 x -0.0188 with the correlation coefficient (R2) = 0.997. The result obtained for each snake fruit fraction for flavonoid level in the methanol fraction was 96.51 g/mL and in ethyl acetate fraction was 55.56 g/mL.
蛇果(Salacca zalacca)沃斯果皮被认为是一种废物，但也有少数人使用这种果皮作为药物。在蛇果皮中起治疗作用的化合物是类黄酮。本研究的目的是测定蛇皮提取物中黄酮类化合物的含量。采用紫外可见分光光度法测定其中黄酮类化合物的含量。甲醇馏分和乙酸乙酯馏分的吸光度分别为0.568和0.319，采用槲皮素线性方程标准，y = 0.0608 x -0.0188，相关系数(R2) = 0.997。结果表明，各蛇果馏分中甲醇馏分黄酮类化合物含量为96.51 g/mL，乙酸乙酯馏分黄酮类化合物含量为55.56 g/mL。
{"title":"ANALISIS KADAR FLAVANOID TOTAL MENGGUNAKAN SPEKTROFOTOMETRI UV-VIS DALAM KULIT BUAH SALAK (Salacca zalacca V.)","authors":"M.Sc Mohammad Adam Mustapa, M. Taupik, L. AdityaRamadhan","doi":"10.3731/jsscr.v1i1.2200","DOIUrl":"https://doi.org/10.3731/jsscr.v1i1.2200","url":null,"abstract":"The Snake Fruit (Salacca zalacca (Gaertn.) Voss) skin is considered as a waste, but there are a small number of people who use this fruit skin as an medicine. A compound that plays a role in snake fruit skin for the treatment is flavonoid. The purpose of this study was to determine the level of flavonoid contained in the extract of snake fruit skin. The method used to determine the amount of flavonoid compound contained in it is the UV-Vis Spectrophotometry method. The result of reading the absorbance value of each snake fruit fraction obtained from the methanol fraction was 0.568 and ethyl acetate fraction of 0.319, which were then calculated by using the quercetin linear equation standard, y = 0.0608 x -0.0188 with the correlation coefficient (R2) = 0.997. The result obtained for each snake fruit fraction for flavonoid level in the methanol fraction was 96.51 g/mL and in ethyl acetate fraction was 55.56 g/mL.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133105916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetes mellitus (DM) is a metabolic disorder characterized by the high blood glucose level (hyperglycemia). This research aims to know the effect of adding combination of red onion (Allium cepa L.) extract and metformin against male house mice (Mus musculus) on reducing the blood glucose level. This study uses oral glucose tolerance test (OGTT) to determine the body's ability to tolerate the glucose administration by using 18 male house mice (Mus musculus) that divided into 6 groups and each group consisting of 3 mice. Group I as the negative control given 1% of NaCMC suspension; Group II as the Positive Control given metformin suspension of 1.95 mg; Group III as the Positive Control given red onion extract suspension of 7.5 mg; group IV as the Positive Control given red onion extract suspension of 15 mg; group V as the Treatment Control I given a combination of onion extract suspension 7.5 mg + metformin 1,95 mg; and group VI as the Treatment Control II given red onion extract suspension of 15 mg + metformin 1,95 mg. This research result is then analysed using One-Way Anova statistical method. The obtained results show that the dose of the Treatment Control II has significant effect on reducing the blood glucose level. This research needs to be followed up by looking at the effectiveness of the drugs combination.
{"title":"PENURUNAN KADAR GLUKOSA MENCIT AKIBAT PEMBERIAN KOMBINASI METRFORMIN DAN EKSTRAK BAWANG MERAH","authors":"E. Djuwarno, W. Abdulkadir","doi":"10.3731/jsscr.v1i1.2195","DOIUrl":"https://doi.org/10.3731/jsscr.v1i1.2195","url":null,"abstract":"Diabetes mellitus (DM) is a metabolic disorder characterized by the high blood glucose level (hyperglycemia). This research aims to know the effect of adding combination of red onion (Allium cepa L.) extract and metformin against male house mice (Mus musculus) on reducing the blood glucose level. This study uses oral glucose tolerance test (OGTT) to determine the body's ability to tolerate the glucose administration by using 18 male house mice (Mus musculus) that divided into 6 groups and each group consisting of 3 mice. Group I as the negative control given 1% of NaCMC suspension; Group II as the Positive Control given metformin suspension of 1.95 mg; Group III as the Positive Control given red onion extract suspension of 7.5 mg; group IV as the Positive Control given red onion extract suspension of 15 mg; group V as the Treatment Control I given a combination of onion extract suspension 7.5 mg + metformin 1,95 mg; and group VI as the Treatment Control II given red onion extract suspension of 15 mg + metformin 1,95 mg. This research result is then analysed using One-Way Anova statistical method. The obtained results show that the dose of the Treatment Control II has significant effect on reducing the blood glucose level. This research needs to be followed up by looking at the effectiveness of the drugs combination.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124046317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-03-01DOI: 10.37311/jsscr.v1i1.2193
Apt Juliyanty Akuba, N. Thomas, Rendy Dwy Jayanto Palay
The ability of mosquitoes as a vector of various diseases such as dengue and malaria. One of the most commonly used methods of eradicating mosquitoes is chemical insecticides aimed at killing adult mosquitoes, which also creates its own problems, namely the emergence of mosquito resistance and toxic effects on humans. Therefore, alternative insecticides that are safer for the environment are needed from plants. One of them uses celery plants (Apium graveolens Linn.). Celery contains essential oils which act as respiratory poisons that can repel or kill mosquitoes. This study aims to see the effect of methanol extract of celery leaves as insecticides on mosquitoes, carried out by spraying on mosquitoes in confinement. Spraying using water as a negative control, baygon as a positive control and each extract solution 5% b / v, 10% b / v and 15% b / v. Spraying on each cage is done 8 times, ie 2 times from the left side of the cage, 2 times from the right side of the cage, 2 times from the front of the cage and 2 times from the back of the cage. The results showed that testing of methanol extract of celery leaves at a concentration of 5%, 10% and 15% could work as a mosquito-killing insecticide.
蚊子作为各种疾病媒介的能力，如登革热和疟疾。消灭蚊子最常用的方法之一是杀死成年蚊子的化学杀虫剂，这也产生了它自己的问题，即蚊子抗药性的出现和对人类的毒性作用。因此，需要从植物中提取对环境更安全的替代杀虫剂。其中之一使用芹菜植物(Apium graveolens Linn.)。芹菜中含有的精油是一种呼吸道毒素，可以驱除或杀死蚊子。本研究旨在观察芹菜叶甲醇提取物作为杀虫剂对蚊子的影响，通过对蚊子进行禁闭喷洒。以水为阴性对照，baygon为阳性对照，每种提取液分别为5% b / v、10% b / v和15% b / v，在每个笼上喷8次，即从笼左侧喷2次，从笼右侧喷2次，从笼前部喷2次，从笼后部喷2次。结果表明，芹菜叶甲醇提取物浓度分别为5%、10%和15%，均可作为杀蚊杀虫剂。
{"title":"EFEK EKSTRAK METANOL DAUN SELEDRI (Apium graveolens Linn.) SEBAGAI INSEKTISIDA TERHADAP NYAMUK","authors":"Apt Juliyanty Akuba, N. Thomas, Rendy Dwy Jayanto Palay","doi":"10.37311/jsscr.v1i1.2193","DOIUrl":"https://doi.org/10.37311/jsscr.v1i1.2193","url":null,"abstract":"The ability of mosquitoes as a vector of various diseases such as dengue and malaria. One of the most commonly used methods of eradicating mosquitoes is chemical insecticides aimed at killing adult mosquitoes, which also creates its own problems, namely the emergence of mosquito resistance and toxic effects on humans. Therefore, alternative insecticides that are safer for the environment are needed from plants. One of them uses celery plants (Apium graveolens Linn.). Celery contains essential oils which act as respiratory poisons that can repel or kill mosquitoes. This study aims to see the effect of methanol extract of celery leaves as insecticides on mosquitoes, carried out by spraying on mosquitoes in confinement. Spraying using water as a negative control, baygon as a positive control and each extract solution 5% b / v, 10% b / v and 15% b / v. Spraying on each cage is done 8 times, ie 2 times from the left side of the cage, 2 times from the right side of the cage, 2 times from the front of the cage and 2 times from the back of the cage. The results showed that testing of methanol extract of celery leaves at a concentration of 5%, 10% and 15% could work as a mosquito-killing insecticide.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124757362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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