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EVALUATION OF ZERO WASTE MANAGEMENT SYSTEM AND ADANA METROPOLITAN MUNICIPALITY ZERO WASTE IMPLEMENTATION 零废物管理系统评价与阿达纳城市零废物实施
Pub Date : 2021-09-19 DOI: 10.32571/ijct.992891
Bulent Sari, Hatice Şebnem Küpeli̇, Hakan Güney, Olcayto Keskinkan
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引用次数: 0
Synthesis, Spectral Characterization, DFT, and Molecular Docking Studies of 2 - ((2,3-Dihydrobenzo [b] [1,4] dioxin-6-yl) (1H-indol-1-yl) methyl) phenol Compound 2 -((2,3-二氢苯并[b][1,4]二恶英-6-基)(1h -吲哚-1-基)甲基)苯酚化合物的合成、光谱表征、DFT及分子对接研究
Pub Date : 2021-09-19 DOI: 10.32571/ijct.943786
Y. Ulaş
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引用次数: 0
BIODEGRADATION OF CHLORPYRIFOS BY BACTERIAL GENUS PSEUDOMONAS PUTIDA 恶臭假单胞菌对毒死蜱的生物降解
Pub Date : 2021-09-10 DOI: 10.32571/ijct.972050
Y. Cuci
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引用次数: 0
Resorcinol Derivatives as Human Acetylcholinesterase Inhibitor: An In Vitro and In Silico Study 间苯二酚衍生物作为人乙酰胆碱酯酶抑制剂的体外和计算机研究
Pub Date : 2021-08-05 DOI: 10.32571/ijct.944620
U. Güller
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引用次数: 2
A Novel Nicotinoyl Thiourea Manganese Complex: Synthesis, Characterization, and Biological Activity Studies 一种新型烟酰硫脲锰配合物:合成、表征及生物活性研究
Pub Date : 2021-07-10 DOI: 10.32571/ijct.940169
F. B. Özgeriş, M. Yildirim, Arzu Görmez, B. Özgeriş
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引用次数: 1
Antifungal Effect Of Some Essential Oil Combinations 一些精油组合的抗真菌效果
Pub Date : 2021-06-30 DOI: 10.32571/IJCT.918738
M. Türkmen, A. Kaya
Bu calismada, Turkiye'nin Hatay ilinin farkli bolgelerinde dogal olarak yetisen Foeniculum vulgare ve Laurus nobilis gibi farkli bitkilerden elde edilen ucucu yaglarin, toprak kaynakli mantar (Sclerotinia sclerotiorum) hastalik etkenlerine karsi in vitro antifungal etkinligi arastirilmistir. Farkli konsantrasyonlardaki ucucu yaglarin ucucu fazi, doza bagli bir sekilde miselyal gelismeyi inhibe etmistir. L. nobilis ucucu yaglarinin ucucu fazlari 7.50 µL'de fungitoksik etki ve 15 µL'de fungisidal etki gosterirken; F. vulgare ucucu yaglari 5.0 µL konsantrasyonda fungitoksik etki ve 7.50 µL'de fungisidal etki gostermistir. Iki ucucu yag, 3 farkli yontem kullanilarak karistirilmis (elle iki ucucu yag karistirilmis; yaglar birlikte damitilarak karistirilmis ve cozucu kullanilarak karistirilmis) ve Sclerotinia sclerotiorum patojenlerine karsi test edilmistir. Sonuclar, ayri ayri elde edilen L. nobilis ve F. vulgare' nin elle karistirilmasiyla elde edilen uygun ucucu yag kombinasyonunun (M-F% 75L% 25) 5.0 uL'de fungisidal etki gosterdigini; L. nobilis ve F. vulgare' nin birlikte damitilmasiyla elde edilen kombinasyonunun (T-F%75L%25) 3.75 µL konsantrasyonda fungisidal etki gosterdigini ve L. nobilis ve F. vulgare ucucu yaglarinin uygun kombinasyonunun hekzanla karistirilmasiyla (S-F% 75L% 25) 3.75 uL'de fungisidal etki gosterdigini ortaya koymustur. Antimikrobiyal aktiviteler, uygun kombinasyonlardaki ucucu yaglarin mantar hastalik etkenlerine karsi tek baslarina kullanilmasindan daha etkili oldugunu ortaya cikarmistir.
本研究调查了从土耳其哈塔伊省不同地区自然生长的不同植物(如茴香和月桂)中提取的精油对土传真菌(硬粒菌)病原体的体外抗真菌活性。不同浓度的精油挥发物对菌丝生长的抑制作用呈剂量依赖性。L. nobilis 精油的挥发相在 7.50 µL 浓度下有杀真菌作用,在 15 µL 浓度下有杀真菌作用,而 F. vulgare 精油在 5.0 µL 浓度下有杀真菌作用,在 7.50 µL 浓度下有杀真菌作用。使用 3 种不同的方法(手工混合两种精油;蒸馏混合两种精油;使用溶剂混合)混合这两种精油,并对病原体 Sclerotinia sclerotiorum 进行了测试。结果表明,通过手工混合 L. nobilis 和 F. vulgare 分别得到的适当精油组合(M-F 75%L 25%)在 5.0 µL 浓度下显示出杀菌效果;通过共同蒸馏得到的 L. nobilis 和 F. vulgare 组合(T-F 75%L 25%)在 3.75 µL 的浓度下显示出杀菌活性;而将茜草精油与正己烷混合的适当组合(S-F 75%L 25%)在 3.75 µL 的浓度下显示出杀菌活性。抗菌活性表明,与单独使用相比,适当组合的精油对真菌病原体更有效。
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引用次数: 0
Comparison of the chemical composition and bioactive properties of extracts prepared from the mature Turkish and Brazilian banana peels 土耳其和巴西成熟香蕉皮提取物的化学成分和生物活性特性比较
Pub Date : 2021-06-13 DOI: 10.32571/ijct.936932
T. Ozen, I. Demirtaş
The banana (Musa sp.) plant grows in tropical and subtropical regions. The fruit of the banana is eaten and the peel of the banana is discarded. In this study, chemical analyzes (HPLCTOF/MS ve GC-MS) and biochemical activities (antioxidant and antimicrobial) of ethyl acetate (Ea) and methanol/chloroform (Me/Ch) extracts prepared from banana peel (Bbp) grown in Brazil and banana peel (Tbp) grown in Turkey were investigated. Cetene, 4-hydroxybenzoic, palmitic, linoleic, stearic, gentisic and syringic acid are the most abundant compounds in the extracts. The total antioxidant activity of Tbp-Ea (A0.5: 36.84 μg/mL), inhibition of lipid peroxidation of Bbp-Ea (IC50: 3.22 μg/mL), reducing power of Tbp-Me/Ch (A0.5: 4.96 μg/mL), DPPH• scavenging activity of Bbp-Ea (IC50: 8.54 μg/mL), metal chelating activity of Tbp-Ea (IC50: 16.54 μg/mL) and H2O2 scavenging activity of TbpMe/Ch (IC50: 0.36 μg/mL) were found the most effective. It was exhibited that extracts were effective against gramnegative and gram-positive bacteria. In conclusion, the phytochemical and biochemical results of the TbP and Bbp extracts will contribute further pharmacological, biochemical and pharmacological investigations.
香蕉(Musa sp.)植物生长在热带和亚热带地区。香蕉的果实被吃掉,香蕉皮被丢弃。本研究对巴西香蕉皮(Bbp)和土耳其香蕉皮(Tbp)制备的乙酸乙酯(Ea)和甲醇/氯仿(Me/Ch)提取物进行了化学分析(hplc /MS /MS)和生化活性(抗氧化和抗菌)研究。萃取物中含量最多的化合物为十六烯、4-羟基苯甲酸、棕榈酸、亚油酸、硬脂酸、黄芪酸和丁香酸。结果表明,Tbp-Ea的总抗氧化活性(A0.5: 36.84 μg/mL)、抑制Bbp-Ea的脂质过氧化(IC50: 3.22 μg/mL)、Tbp-Me/Ch的还原能力(A0.5: 4.96 μg/mL)、Bbp-Ea的DPPH•清除活性(IC50: 8.54 μg/mL)、Tbp-Ea的金属螯合活性(IC50: 16.54 μg/mL)和TbpMe/Ch的H2O2清除活性(IC50: 0.36 μg/mL)最有效。结果表明,提取物对革兰氏阴性菌和革兰氏阳性菌均有效。综上所述,TbP和Bbp提取物的植物化学和生化结果将为进一步的药理学、生化和药理研究提供依据。
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引用次数: 1
Determination of electronic characteristics of tetrahydro pyrimidine derivatives and investigation of usability as anti-corrosion 四氢嘧啶衍生物的电子特性测定及防腐性能研究
Pub Date : 2021-06-07 DOI: 10.32571/ijct.936922
E. Akbas, M. Okay, Erdem Ergan, B. Akbaş
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引用次数: 0
Inhibition Profiles and Molecular Docking Studies of Anti-proliferative Agents Against Aldose Reductase Enzyme 抗增生性药物对醛糖还原酶的抑制特征及分子对接研究
Pub Date : 2021-06-07 DOI: 10.32571/ijct.944049
N. Kılınç
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引用次数: 2
The Anticancer Activity of Chalcone Compounds against Human Prostate Carcinoma Cell And Human Colon Colorectal Adenocarcinoma 查尔酮类化合物对人前列腺癌细胞和人大肠癌的抗癌作用
Pub Date : 2021-06-01 DOI: 10.32571/ijct.910580
Bedriye Seda Kurşun Aktar, A. S. Yaglıoglu, E. E. Oruç-Emre
Cancer is the second most common cause of death in our country and also worldwide. In the cancer treatment are used many methods such as surgery, chemotherapy, radiotherapy and hormone therapy. Despite these methods, a decrease is not observed in cancer cases and in the mortality. In addition, cancer drugs cause serious side effects. Therefore, there is a need for new anticancer drugs. Chalcones have broad anticancer activity against various cancer cells. In this study, the anticancer activities of the chalcone compounds were investigated against PC3 (Human Prostate Carcinoma Cell) and HT29 (Human colon colorectal adenocarcinoma) cell lines. The anticancer activity tests were performed using the BrdU ELISA method. 5 - Fluorouracil (5 - FU) was used as the positive control. Compound 1-7 ( except Compound 3 ) were determined having higher anticancer activity than 5 - FU against PC3 cancer cells. IC 50 values of the compounds 1-7 against PC3 cancer cells were 2.53±0.02 µM ; 4.40±0.03 µM ; 5.86±0.02 µM ; 4.36±0.03 µM; 1.76±0.02 µM ; 1.78±0.03 µM ; 2.31±0.03 µM , respectively.
癌症是我国乃至全世界第二大常见死因。在癌症治疗中使用了许多方法,如手术、化疗、放疗和激素治疗。尽管采用了这些方法,癌症病例和死亡率并未出现下降。此外,抗癌药物会产生严重的副作用。因此,有必要开发新的抗癌药物。查尔酮对多种癌细胞具有广泛的抗癌活性。本实验研究了查尔酮类化合物对人前列腺癌细胞(PC3)和人结肠直肠腺癌细胞(HT29)的抑癌活性。采用BrdU酶联免疫吸附试验进行抗肿瘤活性试验。5 -氟尿嘧啶(5 - FU)作为阳性对照。化合物1-7(除化合物3外)对PC3癌细胞的抗癌活性高于5 - FU。化合物1 ~ 7对PC3癌细胞的ic50值为2.53±0.02µM;4.40±0.03µm;5.86±0.02µm;4.36±0.03µM;1.76±0.02µm;1.78±0.03µm;分别为2.31±0.03µM。
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引用次数: 0
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International Journal of Chemistry and Technology
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