Background: Psoriasis is an autoimmune and common disease that affects 1 to 3% of the world’s population. The appearance and progress of psoriasis are influenced by genetic and environmental factors. Topical steroids have remained the first-line treatment for psoriasis. Long-term use of topical corticosteroids is associated with the risk of side effects. The purpose of this study was to compare the complications and efficacy of topical clobetasol ointment with Salvia officinalis ointment in the treatment of plaque psoriasis. Methods: A topical ointment containing 20% Salvia officinalis was prepared in the pharmaceutical laboratory of Hormozgan University of Medical Sciences. After standardization, this experimental study was performed on 84 voluntary patients with mild plaque psoriasis for two weeks. One group was treated with the prepared S. officinalis ointment twice daily and the other group was treated with topical clobetasol ointment twice daily. In each group, psoriasis severity was assessed using the Psoriasis Area Severity Index (PASI) at determined time points including baseline and one and two weeks after treatment initiation. Results: At the end of treatment (2 weeks), the mean PASI score changed from 2.36 to 1.55 in patients who received topical clobetasol ointment and this score reduced from 2.74 to 2.23 in patients who applied topical S. officinalis ointment. After 14 days of treatment, the mean percentage decrease in mean PASI score was greater in patients who applied topical clobetasol ointment. Conclusion: This study provides evidence that topical clobetasol ointment is more effective than 20% S. officinalis ointment in the treatment of psoriasis. However, S. officinalis ointment can be used as an adjuvant therapy to the main treatments of mild plaque psoriasis.
{"title":"Comparison of the Complications and Efficacy of Topical Clobetasol Ointment with Salvia officinalis Ointment in the Treatment of Plaque Psoriasis","authors":"S. Tavakoli, Amir Hossein Mosalman Haghighi","doi":"10.34172/hmj.2023.8176","DOIUrl":"https://doi.org/10.34172/hmj.2023.8176","url":null,"abstract":"Background: Psoriasis is an autoimmune and common disease that affects 1 to 3% of the world’s population. The appearance and progress of psoriasis are influenced by genetic and environmental factors. Topical steroids have remained the first-line treatment for psoriasis. Long-term use of topical corticosteroids is associated with the risk of side effects. The purpose of this study was to compare the complications and efficacy of topical clobetasol ointment with Salvia officinalis ointment in the treatment of plaque psoriasis. Methods: A topical ointment containing 20% Salvia officinalis was prepared in the pharmaceutical laboratory of Hormozgan University of Medical Sciences. After standardization, this experimental study was performed on 84 voluntary patients with mild plaque psoriasis for two weeks. One group was treated with the prepared S. officinalis ointment twice daily and the other group was treated with topical clobetasol ointment twice daily. In each group, psoriasis severity was assessed using the Psoriasis Area Severity Index (PASI) at determined time points including baseline and one and two weeks after treatment initiation. Results: At the end of treatment (2 weeks), the mean PASI score changed from 2.36 to 1.55 in patients who received topical clobetasol ointment and this score reduced from 2.74 to 2.23 in patients who applied topical S. officinalis ointment. After 14 days of treatment, the mean percentage decrease in mean PASI score was greater in patients who applied topical clobetasol ointment. Conclusion: This study provides evidence that topical clobetasol ointment is more effective than 20% S. officinalis ointment in the treatment of psoriasis. However, S. officinalis ointment can be used as an adjuvant therapy to the main treatments of mild plaque psoriasis.","PeriodicalId":271947,"journal":{"name":"Hormozgan Medical Journal","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127328253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Negahi, Ahmad Tamoradi, Behnam Ahmadi, A. Piroozan, Saeed Hosseini Tashnizi
Background: Although diet-induced migraines affect many people, the triggering foodstuffs are not fully identified yet. Detecting migraine-triggering foods and susceptible individuals assist in effective headache management. The aim of this study was to determine the relationship between eating allergens and developing or exacerbating migraine. Methods: This was a descriptive-analytical cross-sectional study with 230 migraine patients referring to the neurology clinic of Shahid Mohammadi hospital in Bandar Abbas. They were selected through purposive sampling. After obtaining informed consent from the patients, the required data were collected and then underwent analysis. Results: Overall, 52.4% and 47.6% of participants were females and males, respectively. Their mean age was 40.57±14.04. Based on the results, 61.9% of participants were married, and 60.3% of them had a family history of migraine. The average number of headaches per month and the duration of each headache were 3.16-4.19 times and 3.76-4.41 hours, respectively. Based on the findings, sausages (55.6%), carbonated beverages (0.54%), peanuts (0.46%), beef (44.4%), and canned food, coffee, and eggs (41.3%) are the most common foodstuffs that cause or exacerbate migraines. On the other hand, chicken (15.9%), strawberry, rice, and wheat (17.5%) had the least impact on the onset and exacerbation of migraine headaches. Conclusion: According to the results, identifying food allergens and eliminating them from patients’ diets can be effective in the prognosis of migraine and individuals’ quality of life.
{"title":"The Relationship Between Food Allergens and Migraine Among Patients With Migraine Referring to Shahid Mohammadi Neurology Clinic","authors":"A. Negahi, Ahmad Tamoradi, Behnam Ahmadi, A. Piroozan, Saeed Hosseini Tashnizi","doi":"10.34172/hmj.2023.8163","DOIUrl":"https://doi.org/10.34172/hmj.2023.8163","url":null,"abstract":"Background: Although diet-induced migraines affect many people, the triggering foodstuffs are not fully identified yet. Detecting migraine-triggering foods and susceptible individuals assist in effective headache management. The aim of this study was to determine the relationship between eating allergens and developing or exacerbating migraine. Methods: This was a descriptive-analytical cross-sectional study with 230 migraine patients referring to the neurology clinic of Shahid Mohammadi hospital in Bandar Abbas. They were selected through purposive sampling. After obtaining informed consent from the patients, the required data were collected and then underwent analysis. Results: Overall, 52.4% and 47.6% of participants were females and males, respectively. Their mean age was 40.57±14.04. Based on the results, 61.9% of participants were married, and 60.3% of them had a family history of migraine. The average number of headaches per month and the duration of each headache were 3.16-4.19 times and 3.76-4.41 hours, respectively. Based on the findings, sausages (55.6%), carbonated beverages (0.54%), peanuts (0.46%), beef (44.4%), and canned food, coffee, and eggs (41.3%) are the most common foodstuffs that cause or exacerbate migraines. On the other hand, chicken (15.9%), strawberry, rice, and wheat (17.5%) had the least impact on the onset and exacerbation of migraine headaches. Conclusion: According to the results, identifying food allergens and eliminating them from patients’ diets can be effective in the prognosis of migraine and individuals’ quality of life.","PeriodicalId":271947,"journal":{"name":"Hormozgan Medical Journal","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129262080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shideh Rafati, L. Hassani, M. Tamaddondar, A. Sabili
Background: Hemodialysis is a method for removing excess fluid and uremic waste from the body of chronic renal failure (CRF) patients. It stops death in patients with CRF. Various factors can affect the survival of patients undergoing hemodialysis treatment. The current study aimed to determine some factors affecting hemodialysis patients’ survival using the LASSO-Cox approach. Methods: This cross-sectional study examined 252 patients undergoing hemodialysis from 2010 to 2016 in all hospitals of Bandar Abbas, Iran, whose data had been recorded in the hemodialysis unit, or it was possible to obtain their files. The Cox model under the LASSO variable selection technique (LASSO-Cox) was applied for data analysis. The collected data were analyzed using SPSS 23.0 (IBM) software and glmnet and survival packages in R software, version 3.5.1. Results: Overall, 35 (13.9%) death events were observed in this study. The mean follow-up time of 252 patients was equal to 10.93±7.82 years. Based on the results of the Cox-Lasso method, the risk of mortality for patients with a diploma was 49% lower than that of the illiterate group (HR=0.51; 95% CI: 0.02, 0.57; P=0.021). The risk of death for unemployed patients and farmers was 0.66 (HR=1.66; 95% CI: 1.51, 25.79; P=0.004) and 0.29 (HR=1.29; 95% CI: 1.14, 27.40; P=0.005) higher than that of employees, respectively. Further, by an increase in the frequency of dialysis per week, the risk of death was reduced by 0.34 (HR=0.66; 95% CI: 0.04, 0.82; P=0.022), and one unit increase in the duration of dialysis per hour increased the risk of death by 2.23 times (HR=2.23; 95% CI: 1.41, 27.1; P=0.010). Conclusion: Education level, job, frequency of hemodialysis per week, and duration of hemodialysis per hour were the most important variables in the survival of hemodialysis patients. As a result, it seems that more education for nurses working in hemodialysis wards and the involved patients can be useful to heed the recommendations of physicians in terms of the required duration for hemodialysis per hour and the number of sessions per week.
{"title":"Identification of Effective Factors on the Survival of Hemodialysis Patients Using the LASSO-Cox Approach","authors":"Shideh Rafati, L. Hassani, M. Tamaddondar, A. Sabili","doi":"10.34172/hmj.2023.4115","DOIUrl":"https://doi.org/10.34172/hmj.2023.4115","url":null,"abstract":"Background: Hemodialysis is a method for removing excess fluid and uremic waste from the body of chronic renal failure (CRF) patients. It stops death in patients with CRF. Various factors can affect the survival of patients undergoing hemodialysis treatment. The current study aimed to determine some factors affecting hemodialysis patients’ survival using the LASSO-Cox approach. Methods: This cross-sectional study examined 252 patients undergoing hemodialysis from 2010 to 2016 in all hospitals of Bandar Abbas, Iran, whose data had been recorded in the hemodialysis unit, or it was possible to obtain their files. The Cox model under the LASSO variable selection technique (LASSO-Cox) was applied for data analysis. The collected data were analyzed using SPSS 23.0 (IBM) software and glmnet and survival packages in R software, version 3.5.1. Results: Overall, 35 (13.9%) death events were observed in this study. The mean follow-up time of 252 patients was equal to 10.93±7.82 years. Based on the results of the Cox-Lasso method, the risk of mortality for patients with a diploma was 49% lower than that of the illiterate group (HR=0.51; 95% CI: 0.02, 0.57; P=0.021). The risk of death for unemployed patients and farmers was 0.66 (HR=1.66; 95% CI: 1.51, 25.79; P=0.004) and 0.29 (HR=1.29; 95% CI: 1.14, 27.40; P=0.005) higher than that of employees, respectively. Further, by an increase in the frequency of dialysis per week, the risk of death was reduced by 0.34 (HR=0.66; 95% CI: 0.04, 0.82; P=0.022), and one unit increase in the duration of dialysis per hour increased the risk of death by 2.23 times (HR=2.23; 95% CI: 1.41, 27.1; P=0.010). Conclusion: Education level, job, frequency of hemodialysis per week, and duration of hemodialysis per hour were the most important variables in the survival of hemodialysis patients. As a result, it seems that more education for nurses working in hemodialysis wards and the involved patients can be useful to heed the recommendations of physicians in terms of the required duration for hemodialysis per hour and the number of sessions per week.","PeriodicalId":271947,"journal":{"name":"Hormozgan Medical Journal","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127521456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Motahareh Khojasteh Rad, Milad Zahed, H. Jarineshin
Background: Successful insertion of a laryngeal mask airway (LMA) requires deep anesthesia, the proper opening of the mouth, and adequate suppression of upper airway reflexes. Propofol injection can effectively reduce laryngeal reflexes. This study aimed to compare the effectiveness of propofol alone versus propofol plus a muscle relaxant on LMA insertion and hemodynamic parameters during the induction of anesthesia. Methods: This randomized, double-blind clinical study was performed on 70 patients in the age range of 18-65 years who were candidates for surgery in the operating room of Shahid Mohammadi Hospital in Bandar Abbas, Iran in 2020. The patients were randomly divided into two groups of 35. The first group received propofol and normal saline, and the second group received propofol plus cisatracurium. The parameters of ease of LMA insertion, jaw opening, cough and gag reflexes, head and limb movement, laryngospasm, and hemodynamic changes were recorded for investigation. Results: The patients were almost matched in terms of demographic variables. No significant difference was found regarding the ease of LMA insertion and hemodynamic parameters. However, the overall score of ease of LMA insertion was considerably higher in the propofol plus muscle relaxant group (P=0.029). The extubation time was significantly shorter (P<0.001) and the surgery duration was considerably longer (P=0.019) in the propofol plus muscle relaxant group. Conclusion: The findings demonstrated that both techniques were suitable for LMA insertion, and no significant hemodynamic changes were found between the two groups. However, the administration of propofol plus a muscle relaxant was more suitable due to ease of LMA insertion and shorter extubation time.
{"title":"Effect of Propofol Alone and Propofol+Muscle Relaxant Combination on Laryngeal Mask Airway Insertion and Hemodynamic Parameters During Anesthesia Induction: A Randomized Clinical Trial","authors":"Motahareh Khojasteh Rad, Milad Zahed, H. Jarineshin","doi":"10.34172/hmj.2023.8128","DOIUrl":"https://doi.org/10.34172/hmj.2023.8128","url":null,"abstract":"Background: Successful insertion of a laryngeal mask airway (LMA) requires deep anesthesia, the proper opening of the mouth, and adequate suppression of upper airway reflexes. Propofol injection can effectively reduce laryngeal reflexes. This study aimed to compare the effectiveness of propofol alone versus propofol plus a muscle relaxant on LMA insertion and hemodynamic parameters during the induction of anesthesia. Methods: This randomized, double-blind clinical study was performed on 70 patients in the age range of 18-65 years who were candidates for surgery in the operating room of Shahid Mohammadi Hospital in Bandar Abbas, Iran in 2020. The patients were randomly divided into two groups of 35. The first group received propofol and normal saline, and the second group received propofol plus cisatracurium. The parameters of ease of LMA insertion, jaw opening, cough and gag reflexes, head and limb movement, laryngospasm, and hemodynamic changes were recorded for investigation. Results: The patients were almost matched in terms of demographic variables. No significant difference was found regarding the ease of LMA insertion and hemodynamic parameters. However, the overall score of ease of LMA insertion was considerably higher in the propofol plus muscle relaxant group (P=0.029). The extubation time was significantly shorter (P<0.001) and the surgery duration was considerably longer (P=0.019) in the propofol plus muscle relaxant group. Conclusion: The findings demonstrated that both techniques were suitable for LMA insertion, and no significant hemodynamic changes were found between the two groups. However, the administration of propofol plus a muscle relaxant was more suitable due to ease of LMA insertion and shorter extubation time.","PeriodicalId":271947,"journal":{"name":"Hormozgan Medical Journal","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123103273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Alzheimer’s is progressive dementia with loss of nerve cells. Physical activity and the use of nano-pharmaceutical supplements may prevent the progression of Alzheimer’s. The aim of this study was to investigate the effects of resistance training and Folate nano-liposome on the expression of D1 and D2 receptors in the hippocampal tissue of Alzheimer’s rats. Methods: Thirty-three male Wistar rats at the age of eight weeks were prepared from Pasteur Institute and randomly divided into 5 groups (healthy control, Alzheimer’s control, Alzheimer+resistance training, Alzheimer+Folate nano-liposomes, and Alzheimer+resistance training+Folate nano-liposomes). Alzheimer’s was induced, and Folate nano-liposomes were injected as a supplement. The animals were anesthetized, and the hippocampus was analyzed after the last training session. Eventually, a one-way ANOVA test was used to estimate the differences between groups (P≤0.05). Results: The results of one-way ANOVA showed a significant difference between the groups in terms of D1 mRNA and D2 mRNA (P≤0.000). Based on the results of the Bonferroni post hoc test, there was a significant difference between the control group and the Alzheimer’s, Alzheimer’s+resistance training, and Alzheimer’s+Folate nano-liposomes. Similarly, a significant difference was found between the Alzheimer’s group and Alzheimer’s+resistance training and Alzheimer’s+resistance training+Folate nano-liposomes (P≤0.05). Conclusion: Resistance training and Folate nano-liposomes changed the content of D1 and D2 in the brain after Alzheimer’s induction. These changes may be partly due to the synergistic effect of physical activity and nano-pharmaceuticals on preventing or reducing the detrimental effects of pathological conditions. Inflammatory factors appear to be associated with neurotrophic factors during activity and exercise in neurodegenerative diseases.
{"title":"Simultaneous Effect of Resistance Training and Folate Nano-liposome on Dopamine Receptors in the Brain Hippocampus of Alzheimer’s Rats","authors":"F. Nameni, Fatemeh Firuzmand","doi":"10.34172/hmj.2023.3053","DOIUrl":"https://doi.org/10.34172/hmj.2023.3053","url":null,"abstract":"Background: Alzheimer’s is progressive dementia with loss of nerve cells. Physical activity and the use of nano-pharmaceutical supplements may prevent the progression of Alzheimer’s. The aim of this study was to investigate the effects of resistance training and Folate nano-liposome on the expression of D1 and D2 receptors in the hippocampal tissue of Alzheimer’s rats. Methods: Thirty-three male Wistar rats at the age of eight weeks were prepared from Pasteur Institute and randomly divided into 5 groups (healthy control, Alzheimer’s control, Alzheimer+resistance training, Alzheimer+Folate nano-liposomes, and Alzheimer+resistance training+Folate nano-liposomes). Alzheimer’s was induced, and Folate nano-liposomes were injected as a supplement. The animals were anesthetized, and the hippocampus was analyzed after the last training session. Eventually, a one-way ANOVA test was used to estimate the differences between groups (P≤0.05). Results: The results of one-way ANOVA showed a significant difference between the groups in terms of D1 mRNA and D2 mRNA (P≤0.000). Based on the results of the Bonferroni post hoc test, there was a significant difference between the control group and the Alzheimer’s, Alzheimer’s+resistance training, and Alzheimer’s+Folate nano-liposomes. Similarly, a significant difference was found between the Alzheimer’s group and Alzheimer’s+resistance training and Alzheimer’s+resistance training+Folate nano-liposomes (P≤0.05). Conclusion: Resistance training and Folate nano-liposomes changed the content of D1 and D2 in the brain after Alzheimer’s induction. These changes may be partly due to the synergistic effect of physical activity and nano-pharmaceuticals on preventing or reducing the detrimental effects of pathological conditions. Inflammatory factors appear to be associated with neurotrophic factors during activity and exercise in neurodegenerative diseases.","PeriodicalId":271947,"journal":{"name":"Hormozgan Medical Journal","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131442173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-02DOI: 10.34172/hmj.2023.110831
H. Karimi, H. Ahadi, A. Borjali, M. Hatami
Background: Chronic diseases such as multiple sclerosis (MS) can lead to hopelessness, negative emotions and thoughts, and reduced quality of life. The present study aimed to compare the effectiveness of spirituality therapy and mindfulness-based training in increasing the resilience of MS patients. Methods: The present study was a quasi-experimental study adopting a pre-test, post-test, and follow-up design with a control group. The statistical population of this study included all patients referring to the MS Association of Tehran in 2018. Using a convenience sampling method, 60 patients were selected and randomly divided into three groups. Data were collected using the Connor‐Davidson Resilience Scale (CD‐RISC) and analyzed adopting repeated measure analysis of variance. Data were analyzed by SPSS 22 software. Results: The results of repeated measure analysis of variance showed that spirituality and mindfulness-based interventions exerted effect on resilience (P≥0.008). Comparing the results also revealed that spirituality therapy had more powerful effect on resilience (P≥0.001). Conclusion: It was concluded that spirituality therapy and mindfulness-based training were both effective in promoting resilience in MS patients; however, spirituality therapy was found to be more effective in increasing the MS patients’ resilience.
{"title":"Comparison of the Effectiveness of Spirituality Therapy and Mindfulness-Based Training in Promoting Resilience of Multiple Sclerosis Patients","authors":"H. Karimi, H. Ahadi, A. Borjali, M. Hatami","doi":"10.34172/hmj.2023.110831","DOIUrl":"https://doi.org/10.34172/hmj.2023.110831","url":null,"abstract":"Background: Chronic diseases such as multiple sclerosis (MS) can lead to hopelessness, negative emotions and thoughts, and reduced quality of life. The present study aimed to compare the effectiveness of spirituality therapy and mindfulness-based training in increasing the resilience of MS patients. Methods: The present study was a quasi-experimental study adopting a pre-test, post-test, and follow-up design with a control group. The statistical population of this study included all patients referring to the MS Association of Tehran in 2018. Using a convenience sampling method, 60 patients were selected and randomly divided into three groups. Data were collected using the Connor‐Davidson Resilience Scale (CD‐RISC) and analyzed adopting repeated measure analysis of variance. Data were analyzed by SPSS 22 software. Results: The results of repeated measure analysis of variance showed that spirituality and mindfulness-based interventions exerted effect on resilience (P≥0.008). Comparing the results also revealed that spirituality therapy had more powerful effect on resilience (P≥0.001). Conclusion: It was concluded that spirituality therapy and mindfulness-based training were both effective in promoting resilience in MS patients; however, spirituality therapy was found to be more effective in increasing the MS patients’ resilience.","PeriodicalId":271947,"journal":{"name":"Hormozgan Medical Journal","volume":"428 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123440777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atabak Dadashi, Hadi Eshaghi Sani, Kobra Abedinzadeh, F. Shokraneh, A. Amanollahi, Ghazal Zoghi
Background: Forced expiratory volume in 6 seconds (FEV6) is a reliable substitute for forced vital capacity (FVC) to identify pulmonary diseases. This study aimed to determine the diagnostic performance of FEV6 in the detection of obstructive and restrictive spirometric patterns. Methods: In this cross-sectional study, spirometry was performed on patients referred to the occupational medicine clinic of Shahid Mohammadi Hospital, Bandar Abbas, Iran, 2018. Spirometric parameters, including FEV1, FVC, and FEV6, were recorded for those tests meeting the American Thoracic Society (ATS) standards. Taken as the reference, the FEV1/FVC ratio<70% indicated airway obstruction, and the restrictive pattern was defined as FVC<80%. Results: In general, 1100 spirometries were included after meeting the ATS standards. The optimal cut-off of FEV1/FEV6 for the prediction of airway obstruction was 71.45% with a sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy of 97.22%, 98.22%, 89.17%, 99.57%, and 98.09%, respectively. The best cut-off of FEV6 for the prediction of the restrictive pattern was 79.23% with the corresponding diagnostic indices of 97.29%, 99.05%, 94.11%, 99.57%, and 98.81%, respectively. Based on the FEV1/FEV6 cut-off, the frequency of obstruction was 14.27% (157/1100) compared to 13.09% based on FEV1/FVC. The frequency of restriction was 13.90% (153/1100) according to the FEV6 cut-off compared to 13.45% with respect to FVC. Conclusion: Overall, our results indicated the applicability of FEV1/FEV6 as an accepted surrogate for FEV1/FVC to diagnose airway obstruction, particularly to screen for chronic obstructive pulmonary disease (COPD) among high-risk patients. In addition, FEV6 is potentially an appropriate substitute for FVC to detect a restrictive pattern.
{"title":"Diagnostic Performance of Forced Expiratory Volume in Six Seconds for the Detection of Obstructive and Restrictive Pulmonary Diseases in a Population of Young Adults in South of Iran","authors":"Atabak Dadashi, Hadi Eshaghi Sani, Kobra Abedinzadeh, F. Shokraneh, A. Amanollahi, Ghazal Zoghi","doi":"10.34172/hmj.2022.34","DOIUrl":"https://doi.org/10.34172/hmj.2022.34","url":null,"abstract":"Background: Forced expiratory volume in 6 seconds (FEV6) is a reliable substitute for forced vital capacity (FVC) to identify pulmonary diseases. This study aimed to determine the diagnostic performance of FEV6 in the detection of obstructive and restrictive spirometric patterns. Methods: In this cross-sectional study, spirometry was performed on patients referred to the occupational medicine clinic of Shahid Mohammadi Hospital, Bandar Abbas, Iran, 2018. Spirometric parameters, including FEV1, FVC, and FEV6, were recorded for those tests meeting the American Thoracic Society (ATS) standards. Taken as the reference, the FEV1/FVC ratio<70% indicated airway obstruction, and the restrictive pattern was defined as FVC<80%. Results: In general, 1100 spirometries were included after meeting the ATS standards. The optimal cut-off of FEV1/FEV6 for the prediction of airway obstruction was 71.45% with a sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy of 97.22%, 98.22%, 89.17%, 99.57%, and 98.09%, respectively. The best cut-off of FEV6 for the prediction of the restrictive pattern was 79.23% with the corresponding diagnostic indices of 97.29%, 99.05%, 94.11%, 99.57%, and 98.81%, respectively. Based on the FEV1/FEV6 cut-off, the frequency of obstruction was 14.27% (157/1100) compared to 13.09% based on FEV1/FVC. The frequency of restriction was 13.90% (153/1100) according to the FEV6 cut-off compared to 13.45% with respect to FVC. Conclusion: Overall, our results indicated the applicability of FEV1/FEV6 as an accepted surrogate for FEV1/FVC to diagnose airway obstruction, particularly to screen for chronic obstructive pulmonary disease (COPD) among high-risk patients. In addition, FEV6 is potentially an appropriate substitute for FVC to detect a restrictive pattern.","PeriodicalId":271947,"journal":{"name":"Hormozgan Medical Journal","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128482510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seyed Ashkan Tabibzadeh Dezfuli, Hossein Parvizi, M. Raji, Reza Yazdani
Background: The increase in demand for emergency services causes overcrowding in emergency departments. Length of stay in emergency departments also influences overcrowding in emergency departments and is a key factor for monitoring the performance in emergency departments. This study investigated the factors affecting length of stay in patients referred to emergency department in Bandar Abbas, Iran. Methods: This retrospective cross-sectional study was conducted from December 2018 and February 2019 by investigating 234 eligible patients referred to Emergency Department of Shahid Mohammadi. Demographic characteristics were also recorded, which included gender, age, type of disease, triage level, the time for entry to emergency specialist visit, specialist visit to order time, entry to imaging/lab assay, entry to other specialist consultants, and time for entry to final decision. Results: The results did not indicate any significant difference in both genders and all age groups (P>0.05), but entry time to lab/imaging assays was significantly lower in patients under 40 years old (P=0.001). Moreover, specialist visit to order time (P=0.001), entry to lab/imaging assays (P=0.003), and entry to final decision time (P=0.013) were significantly shorter in the patients with cardiac diseases. Furthermore, entry to specialist visit time (P=0.001), entry to lab/imaging assays time (P=0.0212), and entry to final decision time (P=0.004) were significantly lower in the patients with lower levels of triage. Conclusions: Triage levels are contributing factors for lengths of stay in emergency department, and these factors can be used for decreasing emergency department lengths of stay.
{"title":"Factors Affecting Length of Stay in Patients Referred to Emergency Department in Bandar Abbas, Iran","authors":"Seyed Ashkan Tabibzadeh Dezfuli, Hossein Parvizi, M. Raji, Reza Yazdani","doi":"10.34172/hmj.2022.30","DOIUrl":"https://doi.org/10.34172/hmj.2022.30","url":null,"abstract":"Background: The increase in demand for emergency services causes overcrowding in emergency departments. Length of stay in emergency departments also influences overcrowding in emergency departments and is a key factor for monitoring the performance in emergency departments. This study investigated the factors affecting length of stay in patients referred to emergency department in Bandar Abbas, Iran. Methods: This retrospective cross-sectional study was conducted from December 2018 and February 2019 by investigating 234 eligible patients referred to Emergency Department of Shahid Mohammadi. Demographic characteristics were also recorded, which included gender, age, type of disease, triage level, the time for entry to emergency specialist visit, specialist visit to order time, entry to imaging/lab assay, entry to other specialist consultants, and time for entry to final decision. Results: The results did not indicate any significant difference in both genders and all age groups (P>0.05), but entry time to lab/imaging assays was significantly lower in patients under 40 years old (P=0.001). Moreover, specialist visit to order time (P=0.001), entry to lab/imaging assays (P=0.003), and entry to final decision time (P=0.013) were significantly shorter in the patients with cardiac diseases. Furthermore, entry to specialist visit time (P=0.001), entry to lab/imaging assays time (P=0.0212), and entry to final decision time (P=0.004) were significantly lower in the patients with lower levels of triage. Conclusions: Triage levels are contributing factors for lengths of stay in emergency department, and these factors can be used for decreasing emergency department lengths of stay.","PeriodicalId":271947,"journal":{"name":"Hormozgan Medical Journal","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129191641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: It is necessary to help type 2 diabetic patients solve diabetes problems by identifying factors affecting healthy lifestyle and self-care indicators that can be improved using different psychological approaches. This research aimed at determining the effectiveness of the acceptance and commitment therapy (ACT) intervention on healthy lifestyle and self-care indicators in type 2 diabetic patients. Methods: This was a quasi-experimental study with a pre-test, post-test, and follow-up with a control group. The statistical population of the study consisted of patients with type 2 diabetes in the age range of 30-60 years at the Diabetes Clinic of Zahedan University of Medical Sciences in 2019. The sample included 40 patients with type 2 diabetes selected by a convenient sampling method and assigned to ACT (n=20) and control (n=20) groups using a simple randomization method. ACT training was performed in 9 sessions for 90 minutes. Data were collected through the lifestyle questionnaire and self-care behavior questionnaire and analyzed by the multivariate analysis of covariance using SPSS 22. Results: The findings indicated that ACT was effective in increasing healthy lifestyle (P=0.022) and selfcare indices (P<0.001) in type 2 diabetic patients. Conclusion: Overall, ACT could affect healthy lifestyle and self-care indicators in type 2 diabetic patients. Thus, it can be used for decreasing type 2 diabetic patients’ psychological problems.
{"title":"Effectiveness of Acceptance and Commitment Therapy Intervention on Healthy Lifestyle and Self-Care Indicators in Type 2 Diabetic Patients","authors":"Abdolvahed Shahnavazi, M. Sedaghat, M. Sabet","doi":"10.34172/hmj.2022.38","DOIUrl":"https://doi.org/10.34172/hmj.2022.38","url":null,"abstract":"Background: It is necessary to help type 2 diabetic patients solve diabetes problems by identifying factors affecting healthy lifestyle and self-care indicators that can be improved using different psychological approaches. This research aimed at determining the effectiveness of the acceptance and commitment therapy (ACT) intervention on healthy lifestyle and self-care indicators in type 2 diabetic patients. Methods: This was a quasi-experimental study with a pre-test, post-test, and follow-up with a control group. The statistical population of the study consisted of patients with type 2 diabetes in the age range of 30-60 years at the Diabetes Clinic of Zahedan University of Medical Sciences in 2019. The sample included 40 patients with type 2 diabetes selected by a convenient sampling method and assigned to ACT (n=20) and control (n=20) groups using a simple randomization method. ACT training was performed in 9 sessions for 90 minutes. Data were collected through the lifestyle questionnaire and self-care behavior questionnaire and analyzed by the multivariate analysis of covariance using SPSS 22. Results: The findings indicated that ACT was effective in increasing healthy lifestyle (P=0.022) and selfcare indices (P<0.001) in type 2 diabetic patients. Conclusion: Overall, ACT could affect healthy lifestyle and self-care indicators in type 2 diabetic patients. Thus, it can be used for decreasing type 2 diabetic patients’ psychological problems.","PeriodicalId":271947,"journal":{"name":"Hormozgan Medical Journal","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129995342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farhad Mehrabi, Omid Esmaeeli, H. Yousefi, Roghayeh Ezati Rad, M. Nikparvar
Background: Stroke is a significant cause of morbidity and mortality worldwide. The association between non-hemorrhagic stroke and some electrocardiographic and echocardiographic findings shows its potential cardiac source. This study aimed to evaluate electrocardiographic and echocardiographic findings of patients with non-hemorrhagic stroke. Methods: This cross-sectional study included 134 patients with non-hemorrhagic stroke admitted to the neurology ward of Shahid Mohammadi hospital, Bandar Abbas, Iran, from 2018 to 2019. Patients’ characteristics including age, gender, family history of stroke, diabetes, hypertension, dyslipidemia, inadequate physical activity, and smoking were recorded. All patients underwent electrocardiography (ECG) and echocardiography. Results: The patients’ mean age was 68.57±12.08 years. Additionally, 84 patients (62.7%) were male. The most common risk factor was dyslipidemia (72.4%) followed by hypertension (64.9%), diabetes (45.5%), smoking (44.8%), and family history of stroke (17.2%). Inadequate physical activity was found in 69.4% of the patients. The most common ECG finding was old myocardial infarction (MI) accounting for 24.6% of the patients, followed by atrial fibrillation (AF) (14.9%) and new MI (3.7%). The most common echocardiographic finding was significant mitral regurgitation (MR) (23.1%), followed by left ventricular systolic dysfunction (21.6%), significant tricuspid regurgitation (TR) (11.2%), mitral stenosis (MS) (4.5%), aortic stenosis (AS) (4.5%), and mitral annulus calcification (MAC) (2.2%). Conclusion: The most common echocardiographic and ECG findings of patients with non-hemorrhagic stroke in this study were MR and old MI and the most common risk factor was dyslipidemia.
{"title":"Electrocardiographic and Echocardiographic Findings of Patients With Non-hemorrhagic Stroke","authors":"Farhad Mehrabi, Omid Esmaeeli, H. Yousefi, Roghayeh Ezati Rad, M. Nikparvar","doi":"10.34172/hmj.2022.35","DOIUrl":"https://doi.org/10.34172/hmj.2022.35","url":null,"abstract":"Background: Stroke is a significant cause of morbidity and mortality worldwide. The association between non-hemorrhagic stroke and some electrocardiographic and echocardiographic findings shows its potential cardiac source. This study aimed to evaluate electrocardiographic and echocardiographic findings of patients with non-hemorrhagic stroke. Methods: This cross-sectional study included 134 patients with non-hemorrhagic stroke admitted to the neurology ward of Shahid Mohammadi hospital, Bandar Abbas, Iran, from 2018 to 2019. Patients’ characteristics including age, gender, family history of stroke, diabetes, hypertension, dyslipidemia, inadequate physical activity, and smoking were recorded. All patients underwent electrocardiography (ECG) and echocardiography. Results: The patients’ mean age was 68.57±12.08 years. Additionally, 84 patients (62.7%) were male. The most common risk factor was dyslipidemia (72.4%) followed by hypertension (64.9%), diabetes (45.5%), smoking (44.8%), and family history of stroke (17.2%). Inadequate physical activity was found in 69.4% of the patients. The most common ECG finding was old myocardial infarction (MI) accounting for 24.6% of the patients, followed by atrial fibrillation (AF) (14.9%) and new MI (3.7%). The most common echocardiographic finding was significant mitral regurgitation (MR) (23.1%), followed by left ventricular systolic dysfunction (21.6%), significant tricuspid regurgitation (TR) (11.2%), mitral stenosis (MS) (4.5%), aortic stenosis (AS) (4.5%), and mitral annulus calcification (MAC) (2.2%). Conclusion: The most common echocardiographic and ECG findings of patients with non-hemorrhagic stroke in this study were MR and old MI and the most common risk factor was dyslipidemia.","PeriodicalId":271947,"journal":{"name":"Hormozgan Medical Journal","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130994721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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