Pub Date : 2017-07-01DOI: 10.1109/NANO.2017.8117413
Huiren Xu, Jinping Luo, Yang Wang, Yilin Song, Li Wang, Xinxia Cai
Brain-derived neurotrophic factor (BDNF) has been shown to play an important role in numerous processes of functional and structural synaptic plasticity in the mammalian central nervous system. In this work, we report a novel immune microelectrode array (MEA) for electrochemical detection of BDNF without labeling step. The chitosan-thionine-multi-walled carbon nanotubes (CS-THI-MWCNTs) composite films as the bio-sensitive film are modified onto the MEA by electrochemical deposition and successfully adopted to immobilize anti-BDNF for the fabrication of electrochemical immune MEA. The THI acted as an electrochemical indicator for the immune response of BDNF. Due to surface-controlled process of THI redox reaction, the increasing formation of anti-BDNF-BDNF immunocomplex resulted in the decreased response currents of THI and the response currents were inversely proportional to the concentrations of corresponding BDNF. The test results of performance revealed that the label-free electrochemical immune MEA had a good stability, selectivity and the limit of detections for BDNF is 5 pg/mL. A linear calibration plot for detection of BDNF was obtained in a wide concentration range from 0.01 ng/mL to 100 ng/mL (r = 0.9995). This novel electrochemical immune MEA has potential applications to detect BDNF for neuroscience research.
{"title":"Label-free electrochemical detection of brain-derived neurotrophic factor based on a novel immune microelectrode array","authors":"Huiren Xu, Jinping Luo, Yang Wang, Yilin Song, Li Wang, Xinxia Cai","doi":"10.1109/NANO.2017.8117413","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117413","url":null,"abstract":"Brain-derived neurotrophic factor (BDNF) has been shown to play an important role in numerous processes of functional and structural synaptic plasticity in the mammalian central nervous system. In this work, we report a novel immune microelectrode array (MEA) for electrochemical detection of BDNF without labeling step. The chitosan-thionine-multi-walled carbon nanotubes (CS-THI-MWCNTs) composite films as the bio-sensitive film are modified onto the MEA by electrochemical deposition and successfully adopted to immobilize anti-BDNF for the fabrication of electrochemical immune MEA. The THI acted as an electrochemical indicator for the immune response of BDNF. Due to surface-controlled process of THI redox reaction, the increasing formation of anti-BDNF-BDNF immunocomplex resulted in the decreased response currents of THI and the response currents were inversely proportional to the concentrations of corresponding BDNF. The test results of performance revealed that the label-free electrochemical immune MEA had a good stability, selectivity and the limit of detections for BDNF is 5 pg/mL. A linear calibration plot for detection of BDNF was obtained in a wide concentration range from 0.01 ng/mL to 100 ng/mL (r = 0.9995). This novel electrochemical immune MEA has potential applications to detect BDNF for neuroscience research.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116670691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.1109/NANO.2017.8117353
Hongfei Zu, Qing-Ming Wang, Yanqing Zheng
The acoustic wave (AW) sensors can response to a physical, chemical, or biological stimulus in a sensitive and real-time manner, so they have drawn increasing attraction in recent years. Among the AW sensors, the piezoelectric ones show a lot of extraordinary merits such as high resolution, wide frequency and temperature ranges, high stability, low power consumption, and low cost, and they are able to sense many physical and chemical quantities such as temperature, pressure, mass, gas concentration, and liquid viscosity [1-3]. To date, many surface acoustic wave (SAW) sensors [4], thin film bulk acoustic resonators (FBAR) [5], and bulk acoustic wave (BAW) [6] sensors have been reported as mass sensors. Compared to the former two types, BAW mass sensors are with the property of simple preparation process, easy to use, high temperature-tolerance, high repeatability and durability, and little damping, because neither the interdigitated transducers (IDTs) nor the functional piezoelectric thin film is needed. Therefore, piezoelectric BAW mass sensors that can be used at elevated temperature range are ideal devices for thermogravimetric analysis (TGA) applications.
{"title":"High temperature piezoelectric bulk acoustic wave mass sensor for thermogravimetric analysis of nano-layer polymer","authors":"Hongfei Zu, Qing-Ming Wang, Yanqing Zheng","doi":"10.1109/NANO.2017.8117353","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117353","url":null,"abstract":"The acoustic wave (AW) sensors can response to a physical, chemical, or biological stimulus in a sensitive and real-time manner, so they have drawn increasing attraction in recent years. Among the AW sensors, the piezoelectric ones show a lot of extraordinary merits such as high resolution, wide frequency and temperature ranges, high stability, low power consumption, and low cost, and they are able to sense many physical and chemical quantities such as temperature, pressure, mass, gas concentration, and liquid viscosity [1-3]. To date, many surface acoustic wave (SAW) sensors [4], thin film bulk acoustic resonators (FBAR) [5], and bulk acoustic wave (BAW) [6] sensors have been reported as mass sensors. Compared to the former two types, BAW mass sensors are with the property of simple preparation process, easy to use, high temperature-tolerance, high repeatability and durability, and little damping, because neither the interdigitated transducers (IDTs) nor the functional piezoelectric thin film is needed. Therefore, piezoelectric BAW mass sensors that can be used at elevated temperature range are ideal devices for thermogravimetric analysis (TGA) applications.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122428426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.1109/NANO.2017.8117357
Hongmei Dang, E. Ososanya, Nian Zhang, Vijay Singh
Nanowire CdS-CdTe solar cells have been fabricated and their reliability was measured in annealing furnace at 120 °C ambient air for 120 hours. The Numerical simulation models were established to simulate measured J-V characteristics of the nanowire solar cells after fabrication and after the 120 hour thermal annealing. Simulation models demonstrate that donor trap concentration in the CdTe layer is increased from 7.2∗1014/cm3 to 7.6∗1014/cm3 after 120 hour annealing. However, acceptor traps in the CdS nanowires maintain identical concentration after 120 hour annealing. Simulation models indicate that donor traps in the CdTe layer mainly contribute to efficiency loss of the nanowire solar cells. Low defect feature of the CdS nanowires plays a role in device reliability.
{"title":"Numerical modeling and simulation of stable nanowire CdS-CdTe solar cells","authors":"Hongmei Dang, E. Ososanya, Nian Zhang, Vijay Singh","doi":"10.1109/NANO.2017.8117357","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117357","url":null,"abstract":"Nanowire CdS-CdTe solar cells have been fabricated and their reliability was measured in annealing furnace at 120 °C ambient air for 120 hours. The Numerical simulation models were established to simulate measured J-V characteristics of the nanowire solar cells after fabrication and after the 120 hour thermal annealing. Simulation models demonstrate that donor trap concentration in the CdTe layer is increased from 7.2∗1014/cm3 to 7.6∗1014/cm3 after 120 hour annealing. However, acceptor traps in the CdS nanowires maintain identical concentration after 120 hour annealing. Simulation models indicate that donor traps in the CdTe layer mainly contribute to efficiency loss of the nanowire solar cells. Low defect feature of the CdS nanowires plays a role in device reliability.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"326 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122737884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.1109/NANO.2017.8117408
Shiqi Guo, A. Arab, S. Krylyuk, A. Davydov, M. Zaghloul
Recent advances in two-dimensional (2D) transition metal dichalcogenides have demonstrated their potential application in chemical sensors. However, the chemical vapor deposition (CVD) grown molybdenum disulfide (MoS2) humidity sensors are still largely unexplored. In this work, MoS2 thin films were grown on 1 cm2 sapphire substrates through sulfurization of e-beam deposited Mo layers. The MoS2 film morphology, thickness, and crystallinity were characterized by AFM and Raman spectroscopy. The two-terminal devices were fabricated with e-beam evaporated interdigitated electrodes (IDEs) on top of the MoS2 surface. The water vapor sensing was tested at various humidity levels with the observed increase in the device resistance response to humidity due to the charge transfer mechanism. We found the devices to be reproducible and with excellent dynamic hysteresis. The sensitivity, fast response and recovery proved that CVD growth MoS2 thin film could be scaled up for humidity and gas sensing applications.
{"title":"Fabrication and characterization of humidity sensors based on CVD grown MoS2 thin film","authors":"Shiqi Guo, A. Arab, S. Krylyuk, A. Davydov, M. Zaghloul","doi":"10.1109/NANO.2017.8117408","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117408","url":null,"abstract":"Recent advances in two-dimensional (2D) transition metal dichalcogenides have demonstrated their potential application in chemical sensors. However, the chemical vapor deposition (CVD) grown molybdenum disulfide (MoS2) humidity sensors are still largely unexplored. In this work, MoS2 thin films were grown on 1 cm2 sapphire substrates through sulfurization of e-beam deposited Mo layers. The MoS2 film morphology, thickness, and crystallinity were characterized by AFM and Raman spectroscopy. The two-terminal devices were fabricated with e-beam evaporated interdigitated electrodes (IDEs) on top of the MoS2 surface. The water vapor sensing was tested at various humidity levels with the observed increase in the device resistance response to humidity due to the charge transfer mechanism. We found the devices to be reproducible and with excellent dynamic hysteresis. The sensitivity, fast response and recovery proved that CVD growth MoS2 thin film could be scaled up for humidity and gas sensing applications.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131616470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.1109/NANO.2017.8117450
Z. Hamlati, M. Azzaz, D. Martinez-Bianco, J. Blanco, P. Gorria
A nanostructured disordered FeAlSn solid solution of Fe-26% Al-2% Sn composition was obtained from elemental Fe, Al and Sn powders using a high-energy ball mill. X-ray diffraction and electron microscopy supported by Mössbauer spectroscopy techniques have been applied to follow changes in the microstructure, phase composition and magnetic properties in dependence on milling time. The transformation of the phase depends upon the milling time. With the increase of milling time all Al and Sn atoms dissolved in the bcc Fe and the final product of the MA process was the nanocrystalline Fe (Al, Sn) solid solution in a metastable state with large amount of defects and mean crystallite size of 5 nm. The electron microscope observations show morphology of powder particles and changes in chemical composition during mechanical treatment. The changes in composition are observed at samples formed by mechanical alloying. On the other hand the composition of Fe72Al26Sn2 pieces is influenced by milling. Magnetic properties of the nanocrystalline mechanically alloyed FeAlSn were also investigated and were related to the microstructural changes.
{"title":"Nanocrystalline and amorphous FeAlSn alloy prepared by mechanical alloying","authors":"Z. Hamlati, M. Azzaz, D. Martinez-Bianco, J. Blanco, P. Gorria","doi":"10.1109/NANO.2017.8117450","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117450","url":null,"abstract":"A nanostructured disordered FeAlSn solid solution of Fe-26% Al-2% Sn composition was obtained from elemental Fe, Al and Sn powders using a high-energy ball mill. X-ray diffraction and electron microscopy supported by Mössbauer spectroscopy techniques have been applied to follow changes in the microstructure, phase composition and magnetic properties in dependence on milling time. The transformation of the phase depends upon the milling time. With the increase of milling time all Al and Sn atoms dissolved in the bcc Fe and the final product of the MA process was the nanocrystalline Fe (Al, Sn) solid solution in a metastable state with large amount of defects and mean crystallite size of 5 nm. The electron microscope observations show morphology of powder particles and changes in chemical composition during mechanical treatment. The changes in composition are observed at samples formed by mechanical alloying. On the other hand the composition of Fe72Al26Sn2 pieces is influenced by milling. Magnetic properties of the nanocrystalline mechanically alloyed FeAlSn were also investigated and were related to the microstructural changes.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131645211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.1109/NANO.2017.8117497
Amoghavarsha Mahadevegowda, C. Johnston, P. Grant
Nylon-6 and Al based nanocomposite films were fabricated via a scalable vacuum co-deposition technique. The relative deposition rates of the constituent phases — nylon-6 (matrix) and Al (filler) — were varied systematically to yield films of different compositions and their dielectric properties, particularly the measured dielectric constants k, were compared with predictions of effective medium expressions. The effect of absorbed water, temperature and heat treatment on k of the nano-films were studied. X-ray photoelectron spectroscopy revealed the presence of an Al-based oxide, which was correlated to the observed enhancement in the dielectric properties of the nanocomposites. The effect of the relative deposition rates of the constituent phases on k and the chemistry of the deposited films fabricated via co-deposition was studied and explained using X-ray photoelectron spectroscopy results.
{"title":"Nylon-6 based nanocomposite films for capacitor applications","authors":"Amoghavarsha Mahadevegowda, C. Johnston, P. Grant","doi":"10.1109/NANO.2017.8117497","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117497","url":null,"abstract":"Nylon-6 and Al based nanocomposite films were fabricated via a scalable vacuum co-deposition technique. The relative deposition rates of the constituent phases — nylon-6 (matrix) and Al (filler) — were varied systematically to yield films of different compositions and their dielectric properties, particularly the measured dielectric constants k, were compared with predictions of effective medium expressions. The effect of absorbed water, temperature and heat treatment on k of the nano-films were studied. X-ray photoelectron spectroscopy revealed the presence of an Al-based oxide, which was correlated to the observed enhancement in the dielectric properties of the nanocomposites. The effect of the relative deposition rates of the constituent phases on k and the chemistry of the deposited films fabricated via co-deposition was studied and explained using X-ray photoelectron spectroscopy results.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132289313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.1109/NANO.2017.8117436
Quan Tao, F. Lan, Minlin Jiang, Guangyong Li
The low selectivity of nanosensors is one of their major obstacles for their wide deployment. To enhance the selectivity, nanosensor array made from zinc oxide (ZnO) nanowires and carbon nanotubes (CNTs) was assembled through dielectrophoresis (DEP). The fabricated nanosensor array was used to detect ammonia (NH3) in a well-controlled environment at room temperature. Because of their opposite material types, ZnO nanowire based sensor behaved oppositely to CNT based sensor. In this study, it is also demonstrated that DC biases can quickly recover both sensing elements. After collecting sensing signals from two transducers under different NH3 concentrations, the concentration of NH3 can be estimated through regression methods. It is shown that quadratic model with the lasso performs well on the collected data.
{"title":"Fabrication, calibration, and recovery of chemical nanosensor array for ammonia detection","authors":"Quan Tao, F. Lan, Minlin Jiang, Guangyong Li","doi":"10.1109/NANO.2017.8117436","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117436","url":null,"abstract":"The low selectivity of nanosensors is one of their major obstacles for their wide deployment. To enhance the selectivity, nanosensor array made from zinc oxide (ZnO) nanowires and carbon nanotubes (CNTs) was assembled through dielectrophoresis (DEP). The fabricated nanosensor array was used to detect ammonia (NH3) in a well-controlled environment at room temperature. Because of their opposite material types, ZnO nanowire based sensor behaved oppositely to CNT based sensor. In this study, it is also demonstrated that DC biases can quickly recover both sensing elements. After collecting sensing signals from two transducers under different NH3 concentrations, the concentration of NH3 can be estimated through regression methods. It is shown that quadratic model with the lasso performs well on the collected data.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134187537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.1109/NANO.2017.8117477
Ahmed O. Nasif, M. Mahfuz, Jagadeep Thota
In a recent paper [2], we introduced a framework for performing nanomechanical communication, where nanomechanical systems can communicate using mechanical movements to encode and transfer information between a transmitter (TX) and a receiver (RX). The framework considered in [2] was mainly focused on the deterministic model, which is the noise-free case. It was shown that the encoding of movements or motions is key to the transfer of information. In this paper, we address how noise affects such a communication system. We introduce two modes of NMC: synchronous versus asynchronous. We show that synchronous mode can achieve higher transmission rates compared to asynchronous mode. As an example, the symbol error rate expression for a transmitter-receiver pair with 4 degrees of motion is given by analyzing the different motion state transitions.
{"title":"Noise modeling of nanomechanical communication systems","authors":"Ahmed O. Nasif, M. Mahfuz, Jagadeep Thota","doi":"10.1109/NANO.2017.8117477","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117477","url":null,"abstract":"In a recent paper [2], we introduced a framework for performing nanomechanical communication, where nanomechanical systems can communicate using mechanical movements to encode and transfer information between a transmitter (TX) and a receiver (RX). The framework considered in [2] was mainly focused on the deterministic model, which is the noise-free case. It was shown that the encoding of movements or motions is key to the transfer of information. In this paper, we address how noise affects such a communication system. We introduce two modes of NMC: synchronous versus asynchronous. We show that synchronous mode can achieve higher transmission rates compared to asynchronous mode. As an example, the symbol error rate expression for a transmitter-receiver pair with 4 degrees of motion is given by analyzing the different motion state transitions.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125555521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.1109/NANO.2017.8117380
M. Nakajima, Y. Igarashi, Masaru Takeuchi, Nagoki Hisamoto, Y. Hasegawa, T. Fukuda
Rotation manipulation of Caenorhabditis elegans (C. elegans) is presented for higher precision by a microchannel. The C. elegans was trapped within a biocompatible gel bead to rotate by a rotational motor. An alginate was used to form the gel bead. Without immobilization treatment by a sodium azide, the C. elegans moves during solidification of alginate. Then, a cavity was happened in the alginate gel bead. On the other hand, C. elegans was trapped without any cavity after immobilization treatment. The stopping and recovery motions of C. elegans were evaluated through the immobilization treatment experimentally. Finally, the eccentricity of rotational manipulation was evaluated with/without centering by a microchannel. The eccentricity was 35 % higher with the microchannel and high precision rotation was achieved at 0.03 degrees/step of actuator.
{"title":"Higher precision rotational manipulation of C. elegans by microchannel","authors":"M. Nakajima, Y. Igarashi, Masaru Takeuchi, Nagoki Hisamoto, Y. Hasegawa, T. Fukuda","doi":"10.1109/NANO.2017.8117380","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117380","url":null,"abstract":"Rotation manipulation of Caenorhabditis elegans (C. elegans) is presented for higher precision by a microchannel. The C. elegans was trapped within a biocompatible gel bead to rotate by a rotational motor. An alginate was used to form the gel bead. Without immobilization treatment by a sodium azide, the C. elegans moves during solidification of alginate. Then, a cavity was happened in the alginate gel bead. On the other hand, C. elegans was trapped without any cavity after immobilization treatment. The stopping and recovery motions of C. elegans were evaluated through the immobilization treatment experimentally. Finally, the eccentricity of rotational manipulation was evaluated with/without centering by a microchannel. The eccentricity was 35 % higher with the microchannel and high precision rotation was achieved at 0.03 degrees/step of actuator.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"155 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122158685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.1109/NANO.2017.8117340
Nile J. Bunce, R. E. Jimenez, V. I. Petsinger, R. Gupta, S. Karna
Protein templated nanoclusters, specifically gold nanoclusters (AuNCs), have attracted a great deal of attention in the recent years due to their biocompatibility, intense fluorescence, sensing and imaging capabilities. Often, expensive and exotic proteins with limited environmental, chemical, and thermal stabilities have been used. Herein, we present a facile and low cost, synthesis of thermally and environmentally stable, photoactive AuNCs. The protein chosen in this study is chicken egg white (EW), which contains approximately 148 different proteins including ovalbumin, lysosomes, ovotransferrin and tryptophan. The fluorescence emission spectrum of the albumen-templated AuNCs are controllable via pH of the solution. The color tunable EW:AuNC exhibit a high degree of sensitivity to folic acid (FA), offering a sensitive sensor platform for simultaneous sensing and imaging of the vitamin.
{"title":"Mixed protein templated fluorescent gold-nanoclusters allow folic acid sensing","authors":"Nile J. Bunce, R. E. Jimenez, V. I. Petsinger, R. Gupta, S. Karna","doi":"10.1109/NANO.2017.8117340","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117340","url":null,"abstract":"Protein templated nanoclusters, specifically gold nanoclusters (AuNCs), have attracted a great deal of attention in the recent years due to their biocompatibility, intense fluorescence, sensing and imaging capabilities. Often, expensive and exotic proteins with limited environmental, chemical, and thermal stabilities have been used. Herein, we present a facile and low cost, synthesis of thermally and environmentally stable, photoactive AuNCs. The protein chosen in this study is chicken egg white (EW), which contains approximately 148 different proteins including ovalbumin, lysosomes, ovotransferrin and tryptophan. The fluorescence emission spectrum of the albumen-templated AuNCs are controllable via pH of the solution. The color tunable EW:AuNC exhibit a high degree of sensitivity to folic acid (FA), offering a sensitive sensor platform for simultaneous sensing and imaging of the vitamin.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"256 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124209097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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