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IEEE Journal of Electromagnetics, RF, and Microwaves in Medicine and Biology About this Journal IEEE Journal of Electromagnetics, RF, and Microwaves in Medicine and Biology 关于本期刊
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-02-29 DOI: 10.1109/JERM.2024.3362215
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引用次数: 0
IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology Publication Information IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology 出版信息
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-02-29 DOI: 10.1109/JERM.2024.3362211
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引用次数: 0
Field-Circuit Combination Method for Solving the Detuning Problem of Magnetic Resonance Human Body Communication 解决磁共振人体通信失谐问题的场-电路组合方法
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-02-27 DOI: 10.1109/JERM.2024.3367247
Lixuan Huang;Ziliang Wei;Bingheng Chen;Sio Hang Pun;Mang I Vai;Yueming Gao
The technological challenge to realize wearable medical devices is to ensure low power consumption and reliable transmission of communication. Magnetic resonance human body communication (MR HBC) provides ideas to improve the transmission effect. Although the coil's resonance properties have been proposed for MR HBC, the modeling and impedance matching for this method are still in the exploratory stage. However, different human impedances affect the coil resonance frequency to varying extents, leading to individual variability in the degree of magnetic coupling. This paper analyzes the influence of human tissues on the coil through finite element method (FEM) simulation modeling. This effect can be eliminated by employing a dual tunable capacitor matching method based on the field-circuit combination. By dynamically adjusting the values of the dual tunable capacitors in real-time, the human body and the coil can be tuned to a resonant state, effectively improving the degree of magnetic coupling. The results reveal that the proposed method enhances the communication gain by 38.91–42.02 dB at the preset frequency for different human tissues. In vivo experiments verify that the method eliminates the effect of different human impedances on the coil, which is of great significance for further improving the performance of MR HBC.
实现可穿戴医疗设备的技术挑战在于确保低功耗和可靠的通信传输。磁共振人体通信(MR HBC)为改善传输效果提供了思路。虽然已经提出了磁共振人体通信的线圈共振特性,但该方法的建模和阻抗匹配仍处于探索阶段。然而,不同人体阻抗对线圈共振频率的影响程度不同,从而导致磁耦合程度的个体差异性。本文通过有限元法(FEM)模拟建模分析了人体组织对线圈的影响。通过采用基于场-电路组合的双可调电容器匹配方法,可以消除这种影响。通过实时动态调整双可调电容器的值,可将人体和线圈调谐到共振状态,从而有效改善磁耦合度。研究结果表明,在不同人体组织的预设频率下,该方法可将通信增益提高 38.91-42.02 dB。体内实验验证了该方法消除了不同人体阻抗对线圈的影响,这对进一步提高磁共振 HBC 的性能具有重要意义。
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引用次数: 0
Continuous Detection of Fluid Leaks Into the Body by Means of Partially Dissolvable Antennas 利用可部分溶解的天线连续探测漏入人体的液体
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-02-19 DOI: 10.1109/JERM.2024.3363509
Federica Naccarata;Marco Di Cristofano;Gaetano Marrocco
Internal fluid leaks in the human body can be caused by underlying medical disorders. Leakage may also be relevant to implanted stent grafts for the treatment of abdominal aneurysms. Indeed, blood may leak through the stent into the aneurysm sac with the risk of rupture due to increased internal pressure. As standard screenings cannot be performed frequently enough, this paper proposes wireless monitoring of fluid leaks into human body regions exploiting an implanted antenna partially coated by an engineered material and an auto-tuning IC in the UHF RFID band. The presence of fluid modifies the antenna impedance in a controlled way by the hydrolysis of the coating. An indication of this change can be obtained through radiofrequency interrogation from an external reader even when the antenna is implanted at 6 cm. Simulations and tests with a mock-up demonstrated the ability to distinguish the degradation of the bioresorbable coating. The sensor is responsive to up to 3.5 mm$^{3}$ of dissolved coating, with a sensitivity of more 10 units$/$mm$^{3}$. Provided that the size of the coating has been properly engineered, the response of the sensor is robust w.r.t. the unpredictable interaction with the fluid.
人体内部液体渗漏可能是由潜在的疾病引起的。渗漏也可能与用于治疗腹部动脉瘤的植入支架移植物有关。事实上,血液可能会通过支架渗漏到动脉瘤囊中,由于内压增加而有破裂的危险。由于无法频繁进行标准筛查,本文提出了利用部分包裹工程材料的植入式天线和超高频射频识别(UHF RFID)频段的自动调谐集成电路,对渗漏到人体区域的液体进行无线监测。液体的存在会通过涂层的水解以可控的方式改变天线的阻抗。即使天线被植入 6 厘米处,也能通过外部读取器的射频询问获得这种变化的指示。模拟实验表明,该传感器能够分辨生物可吸收涂层的降解情况。该传感器对高达 3.5 mm$^{3}$ 的溶解涂层反应灵敏,灵敏度超过 10 个单位$/$mm$^{3}$。只要涂层的尺寸设计得当,传感器就能在与流体发生不可预测的相互作用时保持稳定的响应。
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引用次数: 0
High-Speed Thermal Imaging Can Resolve Short RF Pulse Effects in Tissue Models 高速热成像技术可分辨组织模型中的短射频脉冲效应
IF 3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-02-19 DOI: 10.1109/JERM.2024.3363906
Daniel W. van der Weide;Dustin Kendig;Mo Shakouri
Using high-speed transient infrared microscopy, we resolve induced heating and subsequent conductive diffusion of pulsed RF energy delivered by bipolar microneedles to tissue-mimicking samples, using high spatial and temporal resolution, non-contact advanced thermal imaging to gain insight into direct heating of tissue proximal to RF electrodes. We use both IR and thermoreflectance in the same microscope and find that for the samples and time scales chosen in this first study, the spatiotemporal resolution of IR microscopy was sufficient to reveal local RF-induced thermal effects.
利用高速瞬态红外显微镜,我们解析了双极微针向组织模拟样本输送脉冲射频能量时的诱导加热和随后的传导扩散,利用高时空分辨率、非接触式先进热成像深入了解射频电极近端组织的直接加热情况。我们在同一显微镜中同时使用红外和热反射技术,发现对于首次研究中选择的样本和时间尺度,红外显微镜的时空分辨率足以揭示局部射频诱导的热效应。
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引用次数: 0
Microwave Vertebrae Strength Probe Development: Robust and Fast Phase Unwrapping Technique 微波椎体强度探头开发:稳健快速的相位解包技术
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-02-19 DOI: 10.1109/JERM.2024.3363148
Paul M. Meaney;Viktor Mattsson;Robin Augustine;Helena Brisby
We have developed a new transmission-based, open-ended coaxial probe for assessing vertebrae strength during spinal fusion surgery. The approach exploits the fact that the probes are within the far field of each other implying that the phase varies linearly with respect to propagation distance. Determining the absolute phase is critical for recovering the associated tissue dielectric properties from which bone strength will be determined. Unfortunately, unwanted multi-path signals corrupt the signals at the lower end of the operating frequency range from which our conventional unwrapping strategy depends. Our new approach requires only three measurements within the prime frequency range and can be determined robustly with a minimum of computations. This will be vital to developing a commercial device since the signal levels will be extremely low power requiring longer than usual data acquisition times, which will be mitigated by measuring the data at only a few frequencies. Fast and efficient operation will be critical for clinical success.
我们开发了一种新的基于传输的开放式同轴探头,用于在脊柱融合手术中评估椎骨强度。该方法利用了探头彼此处于远场范围内这一事实,这意味着相位随传播距离呈线性变化。确定绝对相位对于恢复相关的组织介电特性至关重要,而骨强度将由此确定。遗憾的是,不需要的多路径信号会破坏工作频率范围低端的信号,而我们的传统解包策略正是依赖于这些信号。我们的新方法只需要在主要频率范围内进行三次测量,并能通过最少的计算稳健地确定信号。这对开发商业设备至关重要,因为信号电平将非常低,需要比通常更长的数据采集时间,而只需在几个频率上测量数据就能缓解这一问题。快速高效的操作对于临床成功至关重要。
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引用次数: 0
Improved Multiplicative Regularization for CSI-EPT CSI-EPT 的改进乘法正则化
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-02-16 DOI: 10.1109/JERM.2024.3363428
Florens Helfferich;Peter M. van den Berg;Rob F. Remis
We present an improved multiplicative Contrast Source Inversion (CSI) approach for Electrical Properties Tomography (EPT). In EPT, the conductivity and permittivity profiles of a body part are reconstructed based on a known circularly polarized part of the magnetic field (the $B_{1}^+$-field) that has its support inside the body part of interest. The CSI method attempts to reconstruct these profiles in an iterative and alternating manner by first fixing the contrast and updating the contrast source (product of tissue contrast and electric field) and subsequently fixing the contrast source and updating the contrast. In this paper, regularization is included in a multiplicative way similar to the standard multiplicative CSI-EPT method. However, the regularized objective function is different and an update for the contrast is obtained through one-step Jacobi filtering of a least-squares reconstruction that is based on the updated contrast source. Two-dimensional numerical experiments for conductivity and permittivity tissue profiles of a female body model show that, for data with various noise levels, the proposed regularization approach generally provides improved tissue reconstructions compared with standard multiplicative CSI-EPT.
我们提出了一种用于电特性断层扫描(EPT)的改进型乘法对比源反演(CSI)方法。在 EPT 中,身体部位的电导率和介电常数剖面是根据已知的磁场圆极化部分($B_{1}^+$-场)重建的,该磁场在相关身体部位内部有支撑点。CSI 方法试图以迭代和交替的方式重建这些剖面,首先固定对比度并更新对比度源(组织对比度与电场的乘积),然后固定对比度源并更新对比度。本文采用类似于标准乘法 CSI-EPT 方法的乘法正则化方法。不过,正则化的目标函数有所不同,对比度的更新是通过对基于更新对比度源的最小二乘重建进行一步雅可比滤波获得的。对一个女性人体模型的电导率和介电常数组织剖面进行的二维数值实验表明,与标准的乘法 CSI-EPT 相比,对于各种噪声水平的数据,所提出的正则化方法一般都能提供更好的组织重建。
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引用次数: 0
Thyroid Microwave Ablation Study Based on Fiber Bragg Gratings Thermal Mapping 基于光纤布拉格光栅热成像的甲状腺微波消融研究
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-02-08 DOI: 10.1109/JERM.2024.3358991
Elena De Vita;Francesca De Tommasi;Carlo Altomare;Daniela Lo Presti;Giuseppina Pacella;Agostino Iadicicco;Massimiliano Carassiti;Rosario Francesco Grasso;Carlo Massaroni;Stefania Campopiano;Emiliano Schena
Thyroid nodules represent a widespread health concern and surgery is often adopted even if the incidence of frequent post-operative complications is not negligible. In recent years, this framework has fostered the growing spread of thermal ablation treatments, in particular microwave ablation (MWA). To date, despite its relevance, state-of-the-art regarding temperature monitoring in thyroid tissue during MWA is lacking. In this paper, the effects of MWA in thyroid by monitoring temperatures have been explored. By using several fiber Bragg gratings (FBGs) temperature sensors, the heat maps in the proximity of the MW antenna have been reconstructed for two different power values set at generator. An increase up to about 4.5 cm3 in ablation volume and up to 24 °C in maximum temperature variation as power rises from 20 W to 30 W has been observed. In addition, the dependency of the temperature evolution on the involved power has been investigated, observing that, with increasing power, some FBGs recorded a ΔT slope increase until the maximum values, resulting in shorter ablation times, and others recorded a plateau phase until the end of the MWA treatment. Such a propensity could be relevant to adjust the clinical settings according to the desired treatment outcome.
甲状腺结节是人们普遍关注的健康问题,即使术后并发症频发的几率不容忽视,人们还是经常采用手术治疗。近年来,这一框架促进了热消融治疗,特别是微波消融(MWA)的日益普及。迄今为止,尽管微波消融与甲状腺组织息息相关,但有关微波消融过程中甲状腺组织温度监测的最新研究成果还很缺乏。本文通过监测甲状腺的温度,探讨了微波消融对甲状腺的影响。通过使用多个光纤布拉格光栅(FBGs)温度传感器,在发电机设定的两个不同功率值下重建了MWA天线附近的热图。当功率从 20 W 上升到 30 W 时,烧蚀体积增加了约 4.5 cm3,最大温度变化高达 24 °C。此外,我们还研究了温度变化与相关功率的关系,观察到随着功率的增加,一些 FBG 的 ΔT 斜率增加,直至达到最大值,从而缩短了烧蚀时间,而另一些 FBG 的温度变化则处于平稳阶段,直至 MWA 处理结束。这种倾向可能与根据预期治疗结果调整临床设置有关。
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引用次数: 0
A Coil Rectenna Array Design to Harvest All H-Field Components for Lateral Misalignment Tolerant Wireless Powering of Bio-Medical Implant Devices 线圈整流天线阵列设计可收集所有 H 场成分,实现生物医学植入设备的侧向错位容错无线供电
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-01-22 DOI: 10.1109/JERM.2024.3351751
Vivek Kumar Srivastava;Ashwani Sharma
This paper presents a coil rectenna array design to address the lateral misalignment problem in near-field wireless powering of biomedical implants and wearable devices. For this purpose, the proposed design comprises three non-identical orthogonal coil antennas optimized to harvest three orthogonal H-field components efficiently. The rectified energy generated by these antenna units is utilized to supply power to the load by combining the individual rectified output voltages. Out of the two distinct combining techniques, DC and AC combining, DC combining proved advantageous in effectively harnessing the lateral field components. The design parameters of the orthogonal coil rectennas are optimized to enhance the lateral misalignment tolerance area. To realize the proposed rectenna array, a multi-layer PCB technology is employed, resulting in a compact, robust, and cost-effective solution for wireless powering of biomedical implanted and wearable devices. Experimental validation of the analytical results demonstrates that the proposed design has the potential to significantly mitigate the lateral misalignment problem in a 2D plane, achieving a uniformity percentage of $boldsymbol{38.18}$% for a misalignment tolerance range of $60times 60$ mm$^{2}$.
本文介绍了一种线圈矩形天线阵列设计,以解决生物医学植入物和可穿戴设备近场无线供电中的横向错位问题。为此,所提出的设计由三个非相同的正交线圈天线组成,经过优化后可有效收集三个正交的 H 场分量。利用这些天线单元产生的整流能量,通过组合各个整流输出电压为负载供电。在直流和交流两种不同的组合技术中,直流组合被证明在有效利用横向场分量方面具有优势。对正交线圈整流天线的设计参数进行了优化,以提高横向偏差容限。为实现所提出的矩形天线阵列,采用了多层印刷电路板技术,从而为生物医学植入式和可穿戴设备的无线供电提供了一种紧凑、坚固且经济高效的解决方案。分析结果的实验验证表明,所提出的设计具有显著缓解二维平面横向偏差问题的潜力,在偏差公差范围为 60/times 60$ mm$^{2}$ 的情况下,均匀性百分比达到了 $/boldsymbol{38.18}$%。
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引用次数: 0
On the Low-Cost Production of Tissue-Mimicking Skin Phantoms Up to 40 GHz 低成本制作高达 40 千兆赫的组织仿真皮肤模型
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-01-18 DOI: 10.1109/JERM.2024.3349851
Simona Di Meo;Giulia Matrone;Giovanni Magenes;Marco Pasian
Objectives: In this paper, a simple methodology for making skin phantoms is presented. In addition, the first millimeter (mm)-wave images in scenarios including the skin phantoms are shown. Technology or Method: Two mixtures based on the use of simple and inexpensive materials are produced and dielectrically characterized in the [0.5--40] GHz frequency range. Cole-Cole parameters are derived by the least-squares method. An inexpensive polystyrene mold to obtain morphologically compatible skin thicknesses is presented. Finally, these phantoms are used for experimental mm-wave imaging tests in two scenarios, with targets with different size and reflectivity in air and in an oil-based phantom. Results: The dielectric characteristics of the produced skin phantoms are compared with those of human skin, showing excellent agreement over the entire spectrum. Realistic and uniform thicknesses from 1 to 2.5 mm were obtained. The experimental images show the possibility of detecting targets with different reflectivity below the skin at mm- waves. Conclusions: two phantoms based on safe and low-cost materials emulating dielectric characteristics (up to 40 GHz) and morphological characteristics of the skin were proposed. One of these phantoms has been used for a number of mm-wave imaging system tests in different scenarios, and the potential of mm-waves to detect non-superficial targets even in the presence of skin is demonstrated. Clinical or Biological Impact: the results presented in this paper provide a replicable methodology for skin phantom realization and show the potential feasibility of mm-wave imaging for early detection of breast cancer.
目的:本文介绍了制作皮肤模型的简单方法。此外,还展示了包括皮肤模型在内的场景中的第一毫米波图像。技术或方法:使用简单而廉价的材料制作两种混合物,并在 [0.5--40] GHz 频率范围内对其进行介电特性分析。科尔-科尔参数通过最小二乘法得出。此外,还介绍了一种廉价的聚苯乙烯模具,用于获得形态相容的表皮厚度。最后,这些模型被用于两种情况下的毫米波成像实验测试,一种是在空气中使用不同尺寸和反射率的目标,另一种是在油基模型中使用。测试结果将制作的皮肤模型的介电特性与人体皮肤的介电特性进行了比较,结果表明两者在整个光谱范围内的介电特性非常一致。获得了 1 至 2.5 毫米的真实均匀厚度。实验图像显示,可以在毫米波下探测到皮肤下面具有不同反射率的目标。结论:提出了两个基于安全和低成本材料的模型,模拟皮肤的介电特性(高达 40 GHz)和形态特征。其中一个模型已用于不同情况下的毫米波成像系统测试,并证明了毫米波即使在皮肤存在的情况下也能探测非表层目标的潜力。临床或生物学影响:本文介绍的结果为皮肤模型的实现提供了一种可复制的方法,并展示了毫米波成像用于乳腺癌早期检测的潜在可行性。
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引用次数: 0
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