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Flexible, Stretchable, and MR-Invisible Dielectric Material for Magnetic Resonance Imaging 用于磁共振成像的柔性、可拉伸和不可见介电材料
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2023-10-16 DOI: 10.1109/JERM.2023.3321873
Seyedamin Hashemi;Sri Kirthi Kandala;Benjamin Agbo;Zachary A. Colwell;Kwanjoon Song;Renxuan Xie;Sung-Min Sohn
Flexible, stretchable, and MR-invisible dielectric materials were studied to increase the local magnetic field (B1) and signal-to-noise ratio (SNR) in magnetic resonance imaging. An electromagnetic simulation was performed with different dielectric constants and physical structures to measure the effects on the magnetic field (H) distribution and the specific absorption rate (SAR). After flexible and stretchable dielectric pads composed of silicon carbide (SiC)- and barium titanate (BaTiO3)-based polymer mixtures were fabricated, MR imaging tests with two isotropic phantoms and an oxtail sample were performed in a preclinical 7 T scanner (BioSpec scanner, Bruker). The B1 field intensities and SNR were compared with a reference image. Also, additional noise and image artifacts were evaluated. Simulation results show that wrapping an object with a dielectric material is the most effective method to increase the intensity and uniformity of the H field. The results of MR imaging consistently show a higher B1 field intensity and SNR when utilizing dielectric materials. An improvement of 25.78% and 18.27% in SNR was observed when SiC- and BaTiO3-based dielectric pads were wrapped around an oxtail, respectively. In this work, the first stretchable dielectric materials with MR-invisibility were developed, and their performance was demonstrated with 7 T MR imaging.
研究了柔性、可拉伸和mr不可见的介电材料,以增加磁共振成像中的局部磁场(b1)和信噪比(SNR)。采用不同介电常数和物理结构进行了电磁模拟,测量了不同介电常数和物理结构对介质磁场(H)分布和比吸收率(SAR)的影响。在由碳化硅(SiC)和钛酸钡(BaTiO 3)基聚合物混合物组成的柔性和可拉伸介质垫制成后,在临床前7 T扫描仪(BioSpec扫描仪,Bruker)中进行两个各向同性模型和一个牛尾样品的MR成像测试。将b1场强度和信噪比与参考图像进行比较。此外,还对附加的噪声和图像伪影进行了评估。仿真结果表明,用介质材料包裹物体是提高H场强度和均匀性的最有效方法。磁共振成像结果一致表明,介质材料具有更高的b1场强和信噪比。在牛尾表面包裹SiC基和batio3基介质片,信噪比分别提高了25.78%和18.27%。在这项工作中,开发了第一个具有磁共振不可见性的可拉伸介电材料,并通过7 T磁共振成像证明了它们的性能。
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引用次数: 0
Complex Permittivity Reconstruction Using Skin Surface Reflection and Neural Network for Microwave Breast Imaging 基于皮肤表面反射和神经网络的微波乳房成像复介电常数重建
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2023-10-16 DOI: 10.1109/JERM.2023.3321423
Peixian Zhu;Shouhei Kidera
This study introduces an experimental validation for the complex permittivity profile reconstruction using the multi-layer perceptron (MLP) neural network (NN) approach for quantitative microwave recognition of breast cancer. A direct conversion from the four-dimensional scattered data to the complex permittivity three-dimensional profile can be achieved by combining the MLP-NN and the skin surface rejection preprocessing. The experimental data, measured by ultra-wideband radar equipment using a simplified breast phantom, validates that our approach provides both the real and imaginary parts of complex permittivity profiles, even when using limited numbers of training datasets.
本文介绍了一种利用多层感知器(MLP)神经网络(NN)方法重建复杂介电常数剖面的实验验证方法,用于乳腺癌的定量微波识别。将MLP-NN与蒙皮表面抑制预处理相结合,可以实现从四维散射数据到复杂介电常数三维剖面的直接转换。实验数据由超宽带雷达设备使用简化的乳房幻影测量,验证了我们的方法即使在使用有限数量的训练数据集时也能提供复杂介电常数曲线的实部和虚部。
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引用次数: 0
A Wireless Joint Communication and Localization EMG-Sensing Concept for Movement Disorder Assessment 一种用于运动障碍评估的无线联合通信和定位肌电传感概念
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2023-10-16 DOI: 10.1109/JERM.2023.3321974
Stefan Brückner;Jasmin Kolpak;Fabian Michler;Nikita Shanin;Robert Schober;Amelie Hagelauer;Robert Weigel;Heiko Gaßner;Jürgen Winkler;Björn M. Eskofier;Martin Vossiek
Real-time sensory recording of the musculoskeletal system function is an important tool for the diagnosis, treatment planning, and optimal treatment execution of diseases, such as Parkinson's disease and osteoarthritis. This article presents a new wireless joint communication and localization electromyography (EMG)-sensing concept. An on-body sensor beacon measures EMG signals and wirelessly transmits them. At the same time, the spatial position and movement of the beacon is determined with high precision in real time using these transmitted radio signals. The seamless integration of multiple sensors avoids the need to synchronize and individually set up multiple independently operating sensors. An outstanding feature of the radio localization approach is that it does not require proprietary ultra-wideband signals or complicated time synchronization protocols, allowing for small and energy-efficient implementation. To demonstrate this novel concept, a wireless 3D-localizable EMG sensor was developed and experimentally evaluated. This new type of sensing concept allows, for the first time, the time-synchronous measurement of muscle activity and the underlying movement of the associated body part.
肌肉骨骼系统功能的实时感官记录是疾病诊断、治疗计划和最佳治疗执行的重要工具,如帕金森病和骨关节炎。本文提出了一种新的无线联合通信和定位肌电(EMG)传感概念。身体上的传感器信标测量肌电信号,并将其无线传输。同时,利用这些发射的无线电信号,高精度地实时确定信标的空间位置和运动。多个传感器的无缝集成避免了同步和单独设置多个独立运行的传感器的需要。无线电定位方法的一个突出特点是它不需要专有的超宽带信号或复杂的时间同步协议,允许小型和节能的实现。为了证明这一新颖的概念,开发了一种无线3d定位肌电传感器并进行了实验评估。这种新型传感概念首次允许对肌肉活动和相关身体部位的潜在运动进行时间同步测量。
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引用次数: 0
Heart Rate Variability-Based Obstructive Sleep Apnea Events Classification Using Microwave Doppler Radar 基于心率变异性的阻塞性睡眠呼吸暂停事件微波多普勒雷达分类
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2023-09-27 DOI: 10.1109/JERM.2023.3317304
Syed Doha Uddin;Md. Shafkat Hossain;Shekh M. M. Islam;Victor Lubecke
Obstructive Sleep Apnea (OSA) is the most common type of sleep disorder that consists of multiple episodes of partial or complete closure (apnea, hypopnea) of the upper airway during sleep and underdiagnosed problems as there is no reliable portable in-home sleep monitoring system. Doppler radar system is gaining attention as an in-home sleep monitoring system due to its non-contact and unobtrusive form of measurement. Prior research on Radar-based sleep monitoring systems mostly focused on distinguishing apnea and normal breathing patterns using radar-reflected signal amplitude that can't distinguish accurately apnea and hypopnea events. Apnea and hypopnea events were distinguished using effective radar cross-section (ERCS) for short-scale study and ERCS changes with sleeping postures and so on. In this work, we proposed a heart rate variability-based robust feature extraction technique to distinguish different sleep disorder events such as apnea, hypopnea, and normal breathing. HRV-based feature extraction technique was employed on ten consented OSA participants' clinical studies to find a distinguishable feature known as the power of the low-frequency band (0.04-0.15 Hz) and high-frequency band (HF) (0.15-0.4 Hz). The extracted hyper-feature (HF and LF) was then integrated with the traditional Machine learning classifiers (ML) including k-nearest neighbors (KNN), support vector machine (SVM), and random forest. SVM outperformed other classifiers with an accuracy of 97% for distinguishing different OSA events that also supersedes other reported results (ERCS). The proposed method has several potential applications including in-home sleep monitoring, OSA severity detection, respiratory disorder detection, and so on.
阻塞性睡眠呼吸暂停(OSA)是最常见的睡眠障碍类型,由睡眠期间多次发作的部分或完全关闭(呼吸暂停,低通气)和未确诊的问题组成,因为没有可靠的便携式家庭睡眠监测系统。多普勒雷达系统作为一种家庭睡眠监测系统,由于其非接触式和不显眼的测量形式而越来越受到关注。先前基于雷达的睡眠监测系统的研究主要集中在使用雷达反射信号振幅来区分呼吸暂停和正常呼吸模式,而这种方法无法准确区分呼吸暂停和低呼吸事件。短尺度研究采用有效雷达横截面(ERCS)区分呼吸暂停和低呼吸事件,ERCS随睡眠姿势等变化。在这项工作中,我们提出了一种基于心率变异性的鲁棒特征提取技术来区分不同的睡眠障碍事件,如呼吸暂停、呼吸不足和正常呼吸。基于hrv的特征提取技术被用于10名同意的OSA参与者的临床研究,以找到一个可区分的特征,即低频带(0.04-0.15 Hz)和高频带(HF) (0.15-0.4 Hz)的功率。然后将提取的超特征(HF和LF)与传统的机器学习分类器(ML)集成,包括k近邻(KNN)、支持向量机(SVM)和随机森林。SVM在区分不同OSA事件方面优于其他分类器,准确率为97%,也取代了其他报告的结果(ERCS)。该方法在家庭睡眠监测、OSA严重程度检测、呼吸障碍检测等方面具有潜在的应用前景。
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引用次数: 0
Clothing Effect on Multilayered Skin Model Exposure From 20 GHz to 100 GHz 服装对多层皮肤模型暴露的影响从20 GHz到100 GHz
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2023-09-06 DOI: 10.1109/JERM.2023.3309935
Kun Li;Kensuke Sasaki;Giulia Sacco;Maxim Zhadobov
This study presents a statistical assessment of clothed human skin model exposure from 20 to 100 GHz. Dielectric property data for two typical textile materials, i.e., cotton and wool, were provided for the first time over the entire frequency range. A statistical analysis of the ratio of absorbed power density (APD) to skin temperature elevation was performed by Monte Carlo simulations using a multi-layer skin model with a textile layer. Three key parameters, namely the angle of incidence, cross-polarization power ratio ($bm {XPR}$), and air gap spacing between cloth and skin surface, were considered in the dosimetry analysis. The results show that at an incidence angle up to 60$^circ$, fluctuations of the ratio are observed by varying $bm {XPR}$ from $-$50 to 50 dB. In the 20–100 GHz range, when the $bm {XPR}$ is less than 0 dB, i.e., horizontally polarized wave is dominant, the impact on the ratio caused by either the incident angle or the air gap spacing is marginal. The deviation is increased when $bm {XPR}$ exceeds 0 dB, i.e., vertically polarized wave is dominant, especially above 60 GHz at the incidence angles above 60$^circ$.
本研究提出了一个统计评估的穿着人体皮肤模型暴露在20至100 GHz。首次提供了棉花和羊毛两种典型纺织材料在整个频率范围内的介电性能数据。利用带纺织层的多层皮肤模型,通过蒙特卡罗模拟对吸收功率密度(APD)与皮肤温度升高的比值进行了统计分析。在剂量学分析中考虑了三个关键参数,即入射角、交叉极化功率比($bm {XPR}$)和布料与皮肤表面的气隙间距。结果表明,当入射角为60$^circ$时,在$ $-$50到$ $50 dB范围内改变$ $ bm {XPR}$,可以观察到该比值的波动。在20 ~ 100 GHz范围内,当$bm {XPR}$ < 0 dB,即以水平极化波为主时,入射角和气隙间距对比值的影响都很小。当$bm {XPR}$超过0 dB时,偏差增大,即垂直极化波占主导地位,特别是在60 GHz以上,入射角大于60$^circ$。
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引用次数: 0
On the Feasibility of a High-Sensitivity Imaging System for Biomedical Applications Based on Low-Frequency Magnetic Field 基于低频磁场的生物医学高灵敏度成像系统的可行性研究
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2023-08-31 DOI: 10.1109/JERM.2023.3308377
Sabrina Rotundo;Danilo Brizi;Agostino Monorchio
In this article, the theoretical and experimental feasibility analyses of a high-sensitivity imaging system for non-invasive detection of pathological inclusions within biological tissues are presented. The radiating system, exploiting a low frequency magnetic field operating at 3 MHz, consists of an inner resonant spiral sensor, inductively coupled to an unloaded external planar probe loop. The proposed configuration produces a focused magnetic field distribution, therefore a high-sensitivity imaging with respect to the wavelength can be accomplished (detecting inclusions with size in the order of λ/10000, i.e., 1 cm). In particular, the inclusion detection is carried out by observing the amplitude shift of the external probe loop input impedance while scanning the region of interest, leading to a non-invasive and contactless imaging procedure. In addition, we demonstrate the possibility to detect an inclusion, placed within the investigated tissue, either with or without the use of a ferromagnetic contrast medium. To evaluate the proposed imaging system effectiveness, we first perform full-wave numerical simulations. Then, we report the experimental measurements acquired over a fabricated prototype interacting with a representative biological phantom, observing a very good agreement with the numerical simulations. The results confirm the potential for an innovative near-field imaging system to be employed for non-invasive detection of malignant inclusions, expanding the adoption of low RF frequencies in biomedical applications.
本文介绍了一种用于生物组织内病理内含物无创检测的高灵敏度成像系统的理论和实验可行性分析。该辐射系统利用工作频率为3mhz的低频磁场,由一个内部谐振螺旋传感器组成,该传感器与一个未加载的外部平面探头环路电感耦合。所提出的配置产生了一个聚焦的磁场分布,因此可以实现相对于波长的高灵敏度成像(检测大小为λ/10000的夹杂物,即1 cm)。特别是,在扫描感兴趣的区域时,通过观察外部探针环路输入阻抗的幅度位移来进行夹杂物检测,从而实现非侵入性和非接触式成像过程。此外,我们证明了检测包涵体的可能性,放置在研究组织内,无论使用或不使用铁磁造影剂。为了评估所提出的成像系统的有效性,我们首先进行了全波数值模拟。然后,我们报告了在一个制造的原型上获得的实验测量结果,这些测量结果与数值模拟结果非常吻合。研究结果证实了一种创新的近场成像系统用于恶性包涵体的非侵入性检测的潜力,扩大了低射频在生物医学应用中的应用。
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引用次数: 0
Miniaturized 434 MHz Cavity Encapsulated Patch Antenna for Superficial Hyperthermia Treatment 用于表面热疗治疗的小型化434mhz腔封装贴片天线
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2023-08-29 DOI: 10.1109/JERM.2023.3307220
Muthu Rattina Subash Ramu;Kavitha Arunachalam
A 434 MHz patch antenna encapsulated in a planar metal cavity is reported for hyperthermia (HT) treatment of superficial cancers. The optimized patch antenna is 3.6 cm $ times$ 3.6 cm with return loss > 20 dB, ―10 dB bandwidth of 14 MHz, and predominantly tangential electric field in the near field at 434 MHz. Antenna effective field size (EFS) and penetration depth observed from simulation are 17.22 cm2 and 1.26 cm, respectively. The antenna optimized using bulk body tissue was assessed on heterogeneous human body model followed by experimental verification on tissue-mimicking phantom and ex-vivo bovine tissues. Thermal EFS (TEFS) and thermal effective penetration depth (TEPD) of 20.92 cm2 and 2.05 cm measured in tissue phantoms are comparable to 18.61 cm2 and 2.19 cm determined in simulations. Experiments on homogeneous tissue phantom and heterogeneous ex-vivo bovine tissues show localized power deposition in agreement with the simulations. The metal encapsulated patch antenna with EFS to aperture area ratio of 1.33 is well suited for HT treatment of localized superficial cancer. It is also concluded that it could be used for designing planar array capable of delivering adjustable heating pattern to treat large area diffused superficial cancers.
一种封装在平面金属腔内的434 MHz贴片天线被报道用于热疗(HT)治疗浅表癌症。优化后的贴片天线尺寸为3.6 cm × 3.6 cm,回波损耗> 20 dB, -10 dB带宽为14 MHz,近场以切向电场为主,频率为434 MHz。模拟观测到的天线有效场尺寸(EFS)和穿透深度分别为17.22 cm2和1.26 cm。在异质人体模型上对采用大块人体组织优化的天线进行了评估,然后在模拟组织模型和离体牛组织上进行了实验验证。组织模型中测得的热EFS (TEFS)和热有效穿透深度(TEPD)分别为20.92 cm2和2.05 cm,与模拟中测得的18.61 cm2和2.19 cm相当。在均匀组织模型和异质离体牛组织上的实验表明,局部功率沉积与模拟结果一致。金属封装贴片天线,其电磁场与孔径面积比为1.33,适合于局部浅表性肿瘤的HT治疗。该方法可用于设计可调节加热模式的平面阵列,用于治疗大面积弥漫性浅表癌。
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引用次数: 0
IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology Publication Information IEEE医学和生物学中的电磁学、RF和微波杂志出版信息
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2023-08-22 DOI: 10.1109/JERM.2023.3302662
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引用次数: 0
IEEE Journal of Electromagnetics, RF, and Microwaves in Medicine and Biology About this Journal IEEE医学和生物学中的电磁学、RF和微波杂志关于该杂志
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2023-08-22 DOI: 10.1109/JERM.2023.3302666
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引用次数: 0
Dual Band Coaxial Y-Monopole for Hyperthermia Treatment of Cervical Cancer Delivered Through an Intrauterine Tandem 双波段同轴y单极子通过宫内串联输送热疗治疗宫颈癌
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2023-08-21 DOI: 10.1109/JERM.2023.3304547
Shabeeb Ahamed KP;Joseph Prashanth Britto;Kavitha Arunachalam
In this work, we report a coaxial antenna consisting of a flexible Y-monopole with dual-band operation and low-profile wideband flexible ferrite choke for delivering localized HT treatment at shallow insertion depth of 50 mm inside the cervix using custom fabricated non-metallic intrauterine cervix tandem of 8 mm outer diameter and 1 mm wall thickness. Variable treatment coverage was achieved by selecting the excitation of the dual-band Y-monopole as 915 and 1300 MHz. The Y-monopole is a coaxial wire with a Y-split in the exposed inner conductor and wideband flexible ferrite sheet on the outer conductor to suppress the secondary current. The water loaded Y-monopole inside the intrauterine tandem cervix applicator with 15° bend angle resonated at 915 and 1300 MHz for arm lengths of 21 and 13.5 mm, respectively. The heating characteristics of Y-monopole was assessed using tissue-mimicking phantoms. Phantom measurements indicate dual band operation with power reflection coefficient $ leq -$ 24 dB at 915 and 1300 MHz. The measured extents of 25% axial specific absorption rate in tissue phantom at 915 and 1300 MHz is 39.4 and 28.4 mm, respectively. Localized power deposition with $Delta T = 3$ °C iso-contour of 46.3 mm × 39.2 mm and 37 mm × 31 mm along axial and radial directions was measured at 915 and 1300 MHz, respectively. Phantom measurements demonstrate the ability of the proposed antenna to deliver variable treatment volume to the cervix through 15° intrauterine tandem.
在这项工作中,我们报道了一种同轴天线,由双波段操作的柔性y单极子和低配置宽带柔性铁氧体扼流圈组成,用于在宫颈内50 mm的浅插入深度提供局部高温治疗,使用定制的外径8 mm,壁厚1 mm的非金属宫内子宫颈串联。通过选择双频y单极子激励为915和1300 MHz,实现了不同的处理覆盖。y型单极子是同轴导线,在外露的内导体上有y型裂口,在外导体上有宽带柔性铁氧体片以抑制二次电流。当臂长为21和13.5 mm时,子宫内串联子宫颈施药器内载水y单极子的共振频率分别为915和1300 MHz,弯曲角度为15°。采用组织模拟模型对y型单极子的加热特性进行了评估。幻影测量表明双频工作功率反射系数$ leq -$ 24 dB在915和1300 MHz。测量范围为25% axial specific absorption rate in tissue phantom at 915 and 1300 MHz is 39.4 and 28.4 mm, respectively. Localized power deposition with $Delta T = 3$ °C iso-contour of 46.3 mm × 39.2 mm and 37 mm × 31 mm along axial and radial directions was measured at 915 and 1300 MHz, respectively. Phantom measurements demonstrate the ability of the proposed antenna to deliver variable treatment volume to the cervix through 15° intrauterine tandem.
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引用次数: 0
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