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Impact of MRI Field Strengths on Metasurface Enhancement MRI场强对超表面增强的影响
IF 3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-04-01 DOI: 10.1109/JERM.2025.3548169
Robert Kowal;Lucas Knull;Max Joris Hubmann;Ivan Vogt;Daniel Düx;Florian Maier;Marcel Gutberlet;Bennet Hensen;Frank Wacker;Oliver Speck;Holger Maune
Metasurfaces have proved valuable in magnetic resonance imaging (MRI) applications through modifying the field profiles of radiofrequency coils to enhance imaging. Using metasurfaces to enhance a conventional coil, such as the table-integrated spine coil, allows imaging with practically no cables inside the bore. This work investigated the fundamental relationship between an MRI system's field strength and the enhancement effect of a metasurface. We simulated and manufactured grid metasurfaces for field strengths of 0.55 Tesla (0.55 T), 1.5 T and 3 T and evaluated them experimentally. We found increased enhancements of the signal-to-noise ratio (SNR) with lower field strengths. At 0.55 T, the enhancement in the vicinity of the metasurface (10.9-fold) was measured 3.8 times higher than at 3 T. Moreover, the SNR decreased less with field strength next to the metasurface compared to the spine coil. Our results indicate the capability of metasurfaces in low field MRI systems and can stimulate further research. This could benefit future applications in MRI-guided interventions through simplified handling, as well as countries currently underserved with MRIs due to low manufacturing costs.
超表面通过改变射频线圈的场分布来增强成像,在磁共振成像(MRI)应用中被证明是有价值的。使用超表面来增强传统线圈(如工作台集成脊状线圈),可以在钻孔内几乎没有电缆的情况下进行成像。本研究探讨了MRI系统的场强与超表面增强效应之间的基本关系。我们模拟并制作了0.55 Tesla (0.55 T)、1.5 T和3t场强下的网格超表面,并对其进行了实验评价。我们发现,较低的场强增强了信噪比(SNR)。在0.55 T时,超表面附近的增强(10.9倍)是3 T时的3.8倍,而且与脊柱线圈相比,超表面附近的信噪比随场强的下降较小。我们的结果表明了超表面在低场MRI系统中的能力,并可以激发进一步的研究。通过简化处理,这将有利于mri引导干预措施的未来应用,以及目前由于制造成本低而mri服务不足的国家。
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引用次数: 0
IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology Publication Information 医学和生物学中的电磁学、射频和微波杂志
IF 3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-03-22 DOI: 10.1109/JERM.2025.3568681
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引用次数: 0
IEEE Journal of Electromagnetics, RF, and Microwaves in Medicine and Biology About this Journal 医学和生物学中的电磁学、射频和微波
IF 3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-03-22 DOI: 10.1109/JERM.2025.3568685
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引用次数: 0
Software Defined Radars for Low-Cost Healthcare Monitoring and Imaging Systems: A Comprehensive Review 用于低成本医疗监测和成像系统的软件定义雷达:全面综述
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-03-21 DOI: 10.1109/JERM.2025.3548278
Sandra Costanzo;Syed Doha Uddin;Milad Mokhtari;Amin Abbosh;Changzhi Li
Technological advancements have enabled the implementation of software-defined radars (SDRadar) as low-cost, reconfigurable radar systems using software processing. The adaptability and reusability of SDRadar have expanded their application in many healthcare applications. An SDRadar is usually designed with a basic architecture that includes a transmitter, receiver, and a digital signal processor. The transmitter sends out radio waves, which are reflected, or penetrated and scattered, from the targeted object. Those reflected or scattered signals are captured by the received and processed using a digital signal processor to extract useful information. This flexibility allows SDRadar to be easily reprogrammed for different tasks without changing the hardware. To support and motivate researchers and practitioners of various scientific and engineering expertise, a state-of-the-art review of SDRadar, focusing on the healthcare applications of continuous waves, frequency-modulated continuous waves, and stepped-frequency continuous-wave modes, is presented. The review focuses on heart rate and respiration monitoring, as well as medical radar imaging, over a broad frequency range from 0.2 GHz to 20 GHz. Future research trends and potential advancements are also discussed.
技术的进步使得软件定义雷达(sradar)成为低成本、可重构的雷达系统。SDRadar的适应性和可重用性扩展了其在许多医疗保健应用中的应用。一个雷达通常被设计成一个基本的架构,包括一个发射器,接收器和一个数字信号处理器。发射机发出无线电波,这些电波被目标物体反射或穿透和散射。接收到的反射或散射信号被捕获,并使用数字信号处理器进行处理以提取有用信息。这种灵活性使得sradar可以很容易地重新编程为不同的任务,而无需改变硬件。为了支持和激励各种科学和工程专业知识的研究人员和从业人员,本文介绍了sradar的最新进展,重点介绍了连续波、调频连续波和阶跃频率连续波模式的医疗保健应用。审查的重点是心率和呼吸监测,以及医疗雷达成像,在0.2 GHz至20 GHz的宽频率范围内。并讨论了未来的研究趋势和可能的进展。
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引用次数: 0
Research on Microbial Aerosol Control Device Based on Electromagnetic Field Theory 基于电磁场理论的微生物气溶胶控制装置研究
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-03-19 DOI: 10.1109/JERM.2025.3547881
Naming Zhang;Yinghao Li;Xinze Wang;Gaoyang Pan;Shuya Ning;Han Zhang;Bin Yang;Shuhong Wang
Pathogenic microbial aerosols pose a significant threat to human health. It is essential to quickly and effectively disinfect the air to prevent the spread of pathogens, enhance public health, and guarantee health and safety. Electromagnetic disinfection is a new type of disinfection technology, which has been proven to inactivate various bacteria, viruses, and other microorganisms, and has the advantages of high efficiency and environmental protection. This study proposed an electromagnetic disinfection-based method for microbial aerosol disinfection. Electromagnetic field theory was used to establish the cavity's starting size, and electromagnetic simulation software was used to model and simulate the cavity. Then, a cavity system was established and disinfection experiments were conducted on indoor air and high-concentration microbial aerosols. The results show that when sterilizing indoor natural air, using an electromagnetic field with a frequency of 2450 MHz and a power of 200 W for 70 seconds can kill 93% of the bacteria in the air. In high-concentration aerosol disinfection experiments, the disinfection effect can be significantly improved as the power and action time increases. Most microorganisms can be removed when the electromagnetic field power is 200 W and the action time is 2 minutes. These results indicate that electromagnetic disinfection devices can effectively eliminate microorganisms in aerosols and provide a new method for controlling disease epidemics.
病原微生物气溶胶对人类健康构成重大威胁。快速有效地对空气进行消毒,对防止病原体传播、增进公众健康、保障健康安全至关重要。电磁消毒是一种新型的消毒技术,已被证明可以灭活各种细菌、病毒和其他微生物,具有高效、环保的优点。本研究提出了一种基于电磁消毒的微生物气溶胶消毒方法。利用电磁场理论确定空腔的起始尺寸,利用电磁仿真软件对空腔进行建模和仿真。然后,建立空腔系统,对室内空气和高浓度微生物气溶胶进行消毒实验。结果表明,在对室内自然空气进行灭菌时,使用频率为2450 MHz、功率为200 W的电磁场持续70秒,可杀灭空气中93%的细菌。在高浓度气溶胶消毒实验中,随着功率和作用时间的增加,消毒效果明显提高。当电磁场功率为200w,作用时间为2分钟时,可去除大部分微生物。结果表明,电磁消毒装置可以有效地消除气溶胶中的微生物,为控制疾病流行提供了一种新的方法。
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引用次数: 0
Analysis of the Influence of Phantom Design in Superficial Hyperthermia Quality Assurance Procedures 幻影设计对表面热疗质量保证程序的影响分析
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-03-16 DOI: 10.1109/JERM.2025.3567700
Marco Di Cristofano;Marta Cavagnaro
Oncological radiative hyperthermia (HT) is a therapeutic technique used as an adjuvant in cancer treatments. Depending on the tumour depth, it is named superficial or deep HT. This study focuses on superficial hyperthermia, evaluating critical aspects of quality assurance (QA) procedures to understand their implications for treatment effectiveness. QA protocols involve temperature measurements in non-perfused tissue equivalent phantoms to assess HT device performances. An analytical formulation of the transient bioheat transfer equation, supported by numerical and experimental results, examines the electromagnetic-thermal phenomenon in perfused and non-perfused tissues, analysing stability, heating-up times, and thermal response evolution. Results show that the absence of blood perfusion significantly influences the transient thermal behaviour and temperature distribution, with time-dependent effects. A numerical study explores the temperature distributions induced by an electromagnetic source in a multilayered phantom replicating the QA setup. The influence of dielectric and thermal properties of the materials making the phantom on the QA parameters, such as temperature rise (TR), thermal effective field size (TEFS), and thermal effective penetration depth (TEPD), is assessed. Simulations reveal the impact of thermal properties on temperature profiles, highlighting the importance of designing phantoms with properties representative of real tissues.
肿瘤放射热疗(HT)是一种辅助肿瘤治疗的治疗技术。根据肿瘤的深度,它被称为浅表性HT或深部HT。本研究的重点是表面热疗,评估质量保证(QA)程序的关键方面,以了解其对治疗效果的影响。QA方案涉及非灌注组织等效模型的温度测量,以评估高温疗法装置的性能。在数值和实验结果的支持下,瞬态生物传热方程的解析公式检查了灌注和非灌注组织中的电磁热现象,分析了稳定性,加热时间和热响应演变。结果表明,无血流灌注显著影响瞬态热行为和温度分布,且具有时间依赖性。一项数值研究探讨了由电磁源引起的温度分布在多层模体中复制QA装置。研究了制造模体材料的介电性能和热性能对QA参数(如温升(TR)、热效应场尺寸(TEFS)和热效应穿透深度(TEPD))的影响。模拟揭示了热特性对温度分布的影响,强调了设计具有真实组织特性的模型的重要性。
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引用次数: 0
Non-Contact Dielectric Spectroscopy of Multi-Layered Substrates: Towards Organ-on-Chip Applications 多层衬底的非接触介电光谱:迈向芯片上器官的应用
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-02-27 DOI: 10.1109/JERM.2025.3538953
Tim Hosman;Massimo Mastrangeli;Marco Spirito
Dielectric spectroscopy is a label-free, non-contact, real-time, multi-layer sensing technology, and has been used for identification and quantification of many biological materials. A combination of such sensing features is in demand for monitoring of organ-on-chip systems; however available sensing technologies have yet to address this need. In this work, we explore the possibility of leveraging the inherent features of dielectric spectroscopy for the application in organ-on-chip systems, by investigating three key technological developments using open-ended coaxial probes. Firstly, biocompatible non-contact sensing capabilities are proved by showing similar sensing performance of Parylene C-coated probes and uncoated probes. Secondly, a setup and methodology are developed for highly accurate and non-destructive height positioning of the probe to allow for precise extraction of intermediate sample layers. Finally, non-contact multi-layer sensing performance of the presented technology is successfully demonstrated by means of a biological phantom in a three-layered system. With further integration, dielectric spectroscopy can potentially become a cornerstone sensing technique for organ-on-chip by enabling real-time non-contact tracking of various tissue contents and properties.
介电光谱是一种无标签、非接触、实时、多层传感技术,已被用于许多生物材料的鉴定和定量。对器官芯片系统的监测需要这些传感功能的组合;然而,现有的传感技术尚未满足这一需求。在这项工作中,我们通过研究使用开放式同轴探头的三个关键技术发展,探索利用介电光谱的固有特征在器官芯片系统中应用的可能性。首先,通过显示聚对二甲苯c涂层探针与非涂层探针的相似传感性能,证明了其生物相容性非接触传感能力。其次,开发了一种用于高精度和非破坏性探针高度定位的装置和方法,以允许精确提取中间样品层。最后,通过三层系统中的生物幻影,成功地验证了该技术的非接触式多层传感性能。通过进一步集成,电介质光谱可以成为芯片上器官的基础传感技术,实现对各种组织内容和特性的实时非接触式跟踪。
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引用次数: 0
Principal Component Regression for Broadband Microwave-Microfluidic Chemometrics on Small Sample Counts 基于小样本计数的宽带微波微流控化学计量学的主成分回归
IF 3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-02-26 DOI: 10.1109/JERM.2025.3537462
Marie Mertens;Raphaël Trouillon;Tomislav Markovic;Ke Wu;Dominique Schreurs
While broadband dielectric spectroscopy enables label-free analysis of biological and chemical materials, extracting multiple concentrations from the data has remained a challenge. This work is one of the first demonstrations of simultaneous concentration extraction of three liquid constituents in a solution using broadband microwave spectroscopic data. Furthermore, the used methods eliminate the need for de-embedding or characterizing the measurement setup, simplifying the process. Advanced regression techniques such as Principal Component Regression (PCR) and Principal Least Squares (PLS) are applied to determine the concentrations of sodium chloride, glucose, and ethanol in water. As input data, $S$-parameters are measured between 0.5 and 26.5 GHz on a broadband coplanar waveguide sensor with a microfluidic container to transport the liquids. The training datasets consist of 27 and 34 samples, respectively. The mean absolute percentage error for sodium chloride predictions ranged from 3-5% for the different methods, while the minimal errors for glucose and ethanol predictions were 6-7% and 4-6%, respectively.
虽然宽带介电光谱可以实现生物和化学材料的无标签分析,但从数据中提取多种浓度仍然是一个挑战。这项工作是利用宽带微波光谱数据同时浓缩提取溶液中三种液体成分的首次演示之一。此外,所使用的方法消除了去嵌入或表征测量设置的需要,简化了过程。先进的回归技术,如主成分回归(PCR)和主最小二乘(PLS)被应用于确定氯化钠,葡萄糖和乙醇在水中的浓度。作为输入数据,$S$参数在0.5和26.5 GHz之间的宽带共面波导传感器上测量,微流体容器用于传输液体。训练数据集分别由27个和34个样本组成。不同方法预测氯化钠的平均绝对百分比误差在3-5%之间,而葡萄糖和乙醇预测的最小误差分别为6-7%和4-6%。
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引用次数: 0
Extending the MaRCoS: A 4-Rx Open-Source MRI Console for Low-, Mid-, and High-Field Systems 扩展MaRCoS:用于低场、中场和高场系统的4-Rx开源MRI控制台
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-02-24 DOI: 10.1109/JERM.2025.3530968
Hanlei Wang;Feiyang Lou;Yiman Huang;Yang Gao;Xiaotong Zhang
The fast advancement of low-field MRI (magnetic resonance imaging) has generated a high demand for cost-effective and versatile consoles for MRI scanners. MaRCoS (MAgnetic Resonance COntrol System) is such an open-source system that has been well-tested on various low-field systems. However, due to limitations of the basic hardware, MaRCoS is constrained in its ability to support a wide range of field strengths and RF (radio-frequency) channels. In this study, we aim to port the MaRCoS console to high-field (up to 125 MHz Larmor frequency) MRI systems and increase the number of RF receive channels, enabling phased-array coils and/or active EMI (electromagnetic interference) elimination techniques. A series of implementations were conducted across 0.11-, 0.5-, and 1.5-Tesla MRI systems, to evaluate its compatibility and performance. Promising results indicate that the extended console not only matches but, to some extent, surpasses the performance of a commercial console, particularly in terms of flexibility and accessibility. It is hoped that this study could effectively expand the scope of open-source MRI technology, making MRI scans more accessible and affordable.
低场MRI(磁共振成像)的快速发展对MRI扫描仪的成本效益和多功能控制台产生了很高的需求。MaRCoS(磁共振控制系统)就是这样一个开源系统,已经在各种低场系统上经过了很好的测试。然而,由于基本硬件的限制,MaRCoS在支持大范围场强和RF(射频)通道方面的能力受到限制。在本研究中,我们的目标是将MaRCoS控制台移植到高场(高达125 MHz Larmor频率)MRI系统中,并增加射频接收通道的数量,从而实现相控阵线圈和/或有源EMI(电磁干扰)消除技术。在0.11、0.5和1.5特斯拉MRI系统上进行了一系列的实施,以评估其兼容性和性能。有希望的结果表明,扩展主机不仅匹配,而且在某种程度上超过了商业主机的性能,特别是在灵活性和可访问性方面。希望本研究能够有效扩大开源MRI技术的范围,使MRI扫描更容易获得和负担得起。
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引用次数: 0
Flexible Implementation of Open-Ended Coaxial Probes for Dielectric Characterization of Biological Tissues 用于生物组织介质表征的开放式同轴探针的灵活实现
IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-02-24 DOI: 10.1109/JERM.2025.3539549
Ali Farshkaran;Emily Porter
Open-ended coaxial probes are commonly used for characterizing the dielectric properties of biological tissues across the microwave frequency range. They uniquely enable broadband, non-destructive measurements, and can be used in-vivo. These dielectric probes are typically long, straight, rigid instruments. For some clinical in-vivo applications use of the probes in curved positions may be convenient to facilitate access to difficult to reach areas. In this work, we study the potential for performing measurements with probes flexed to different radii of curvature, and assess the accuracy in the resulting complex permittivity. We perform both electromagnetic simulations and experimental measurements, with a variety of curvatures and different tissue test materials. The results indicate that accurate dielectric properties can be achieved even when open-ended coaxial probes are curved to a high degree.
开放式同轴探针通常用于表征生物组织在微波频率范围内的介电特性。它们独特地实现了宽带、非破坏性测量,并且可以在体内使用。这些介电探针通常是长、直、刚性的仪器。对于一些临床体内应用,在弯曲位置使用探针可能更方便,以方便进入难以到达的区域。在这项工作中,我们研究了用弯曲到不同曲率半径的探针进行测量的潜力,并评估了由此产生的复介电常数的准确性。我们使用各种曲率和不同的组织测试材料进行电磁模拟和实验测量。结果表明,即使开放式同轴探头高度弯曲,也能获得精确的介电性能。
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引用次数: 0
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IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology
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