Mehmet Büyükşireci, Dilek Eker Büyükşireci, A. Doğan
Aim: Carotid artery intima-media thickness is thought strong predictor of cardiovascular diseases. To evaluate the common carotid artery intima-media thickness (CCIMT) in female patients with fibromiyalgia (FM) and determine its relationship with disease activity, severity of fibromyalgia, anxiety and depression levels.Material and Method: Thirty nine patients who had fibromyalgia syndrome according to 2016 American College of Rheumatology (ACR) classification criteria and 41 healthy controls were included. Pain level and disease activities were assessed with Numerical Rating Scale (NRS) and Fibromyalgia Impact Questionnairre (FIQ) respectively. According to ACR 2016 classification criteria, Widespread Pain Index (WPI), Symptom Severity Score and Hospital Anxiety and Depression Scale (HADS) were performed. The LDL , HDL and Triglyceride levels were evaluated. Bilateral common carotid artery intima-media thicknesses (CCIMT) were performed by a blind radiologist to the groups of participants. Results: Age, weight and height were similar between groups (p>0.05). Triglyceride level was significant higher in patients with FM (p=0.001). HDL and LDL levels were similar between groups (p=0.297, p=0.061). Bilateral CCIMT was significantly higher in patients with FM (p<0.001). Bilateral CCIMT were found positively correlated with age in FM group (r=0.390, p=0.014, r=0.404, p=0.011 respectively). There were found no correlations between bilateral CCIMT, height, weight, triglyseride level, LDL level, FIQ, NRS, WPI, Symptom Severity Score, HADS scores. . Conclusion: In FM patients, bilateral CCIMTs were found increased compared to healthy controls. No associations were found between CCIMT, LDL, triglyceride levels, disease activity and pain level, anxiety and depression level in patients with FM.
{"title":"Evaluation of carotid intima-media thickness of female fibromyalgia patients and determination of their relationship with disease activity, severity of fibromyalgia, anxiety and depression levels","authors":"Mehmet Büyükşireci, Dilek Eker Büyükşireci, A. Doğan","doi":"10.38053/acmj.1205466","DOIUrl":"https://doi.org/10.38053/acmj.1205466","url":null,"abstract":"Aim: Carotid artery intima-media thickness is thought strong predictor of cardiovascular diseases. To evaluate the common carotid artery intima-media thickness (CCIMT) in female patients with fibromiyalgia (FM) and determine its relationship with disease activity, severity of fibromyalgia, anxiety and depression levels.Material and Method: Thirty nine patients who had fibromyalgia syndrome according to 2016 American College of Rheumatology (ACR) classification criteria and 41 healthy controls were included. Pain level and disease activities were assessed with Numerical Rating Scale (NRS) and Fibromyalgia Impact Questionnairre (FIQ) respectively. According to ACR 2016 classification criteria, Widespread Pain Index (WPI), Symptom Severity Score and Hospital Anxiety and Depression Scale (HADS) were performed. The LDL , HDL and Triglyceride levels were evaluated. Bilateral common carotid artery intima-media thicknesses (CCIMT) were performed by a blind radiologist to the groups of participants. Results: Age, weight and height were similar between groups (p>0.05). Triglyceride level was significant higher in patients with FM (p=0.001). HDL and LDL levels were similar between groups (p=0.297, p=0.061). Bilateral CCIMT was significantly higher in patients with FM (p<0.001). Bilateral CCIMT were found positively correlated with age in FM group (r=0.390, p=0.014, r=0.404, p=0.011 respectively). There were found no correlations between bilateral CCIMT, height, weight, triglyseride level, LDL level, FIQ, NRS, WPI, Symptom Severity Score, HADS scores. . Conclusion: In FM patients, bilateral CCIMTs were found increased compared to healthy controls. No associations were found between CCIMT, LDL, triglyceride levels, disease activity and pain level, anxiety and depression level in patients with FM. ","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114414887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Murat Önal, M. Ağar, Ayşe Şeyma Küçükakça, T. Gürbüz
Aim: This study aimed to evaluate the most suitable endometrial preparation protocols such as hormone replacement therapy (HRT) with gonadotropin releasing hormone analogue (GnRH-a) suppression, HRT without GnRH-a suppression and mild ovarian stimulation (OS) for women with polycystic ovary syndrome (PCOS) undergoing frozen-thawed embryo transfer (FET).Material and Method: We conducted a historical cohort analysis of 161 women with PCOS who underwent the “freeze-all” strategy between December 2018 and August 2020 because of their high risk for ovarian hyperstimulation syndrome. Three endometrial preparation protocols were used: HRT with GnRH-a suppression (n=43); HRT without GnRH-a suppression (n=86); mild-OS (n=32).Results: The biochemical pregnancy results (55.8 % vs 54.65 % vs 53, p=0.900), ongoing pregnancy rates (44.2 % vs 43 % vs 40.62, p=0.572), and abort rates (20.8 % vs 21.3 % vs 23.52, p=0.900) were similar between the HRT with GnRH-a suppression, without GnRH-a suppression and mild-OS, respectively. This study showed no statistically significant difference between the three protocols in laboratory parameters (p>0.05). Conclusion: There was no statistically difference between three groups in terms of pregnancy outcomes. Dependent on clinical experience and facility, one of these protocols could be deployed for FET in women with PCOS.
目的:本研究旨在探讨抑制促性腺激素释放激素类似物(GnRH-a)的激素替代疗法(HRT)、不抑制GnRH-a的激素替代疗法(HRT)和轻度卵巢刺激(OS)治疗多囊卵巢综合征(PCOS)冷冻胚胎移植(FET)的子宫内膜准备方案。材料和方法:我们对161名PCOS女性进行了历史队列分析，这些女性在2018年12月至2020年8月期间因卵巢过度刺激综合征的高风险而接受了“冷冻”策略。采用三种子宫内膜准备方案:HRT联合GnRH-a抑制(n=43);HRT未抑制GnRH-a (n=86);mild-OS (n = 32)。结果:GnRH-a抑制组生化妊娠结果(55.8% vs 54.65% vs 53.3%， p=0.900)、妊娠持续率(44.2% vs 43% vs 40.62, p=0.572)、流产率(20.8% vs 21.3% vs 23.52, p=0.900)与轻度os组差异无统计学意义。本研究显示，三种方案的实验室参数差异无统计学意义(p>0.05)。结论:三组妊娠结局无统计学差异。根据临床经验和设施的不同，这些方案之一可以用于PCOS妇女的FET。
{"title":"Comparison of different endometrial preparation protocols in frozen-thawed embryo transfer cycles in women with polycystic ovary syndrome","authors":"Murat Önal, M. Ağar, Ayşe Şeyma Küçükakça, T. Gürbüz","doi":"10.38053/acmj.1218259","DOIUrl":"https://doi.org/10.38053/acmj.1218259","url":null,"abstract":"Aim: This study aimed to evaluate the most suitable endometrial preparation protocols such as hormone replacement therapy (HRT) with gonadotropin releasing hormone analogue (GnRH-a) suppression, HRT without GnRH-a suppression and mild ovarian stimulation (OS) for women with polycystic ovary syndrome (PCOS) undergoing frozen-thawed embryo transfer (FET).Material and Method: We conducted a historical cohort analysis of 161 women with PCOS who underwent the “freeze-all” strategy between December 2018 and August 2020 because of their high risk for ovarian hyperstimulation syndrome. Three endometrial preparation protocols were used: HRT with GnRH-a suppression (n=43); HRT without GnRH-a suppression (n=86); mild-OS (n=32).Results: The biochemical pregnancy results (55.8 % vs 54.65 % vs 53, p=0.900), ongoing pregnancy rates (44.2 % vs 43 % vs 40.62, p=0.572), and abort rates (20.8 % vs 21.3 % vs 23.52, p=0.900) were similar between the HRT with GnRH-a suppression, without GnRH-a suppression and mild-OS, respectively. This study showed no statistically significant difference between the three protocols in laboratory parameters (p>0.05). Conclusion: There was no statistically difference between three groups in terms of pregnancy outcomes. Dependent on clinical experience and facility, one of these protocols could be deployed for FET in women with PCOS.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"529 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123448616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: SARS-CoV-2 infection frequently affects the lungs, it can also cause severe inflammation in the lower respiratory tract, leading to tracheal damage. We aimed to investigate the relationship between the mean tracheal air column and COVID-19.Material and Method: Chest computed tomography scans of COVID-19 patients treated in an intensive care unit between June 1st, 2020 and October 1st 2022 were retrospectively evaluated. The air column area of the trachea was measured and the effect of the values obtained on mortality and length of stay in the intensive care unit for patients COVID-19 was examined.Results: We found that an increase in the mean tracheal air column increased mortality by 1.218 times. We also determined that an increase in the mean area of the tracheal air column increased the length of stay in the intensive care unit. Furthermore, we showed that advanced age and an increase in the length of stay in the intensive care unit were factors that increased mortality.Conclusion: Tracheomegaly is a poor prognostic factor in COVID-19 disease and is easily diagnosed with CT.
{"title":"Prognosis prediction of the mean tracheal air column area in COVID-19 patients","authors":"Mahmut Corapli, Gokhan Corapli","doi":"10.38053/acmj.1206657","DOIUrl":"https://doi.org/10.38053/acmj.1206657","url":null,"abstract":"Aim: SARS-CoV-2 infection frequently affects the lungs, it can also cause severe inflammation in the lower respiratory tract, leading to tracheal damage. We aimed to investigate the relationship between the mean tracheal air column and COVID-19.Material and Method: Chest computed tomography scans of COVID-19 patients treated in an intensive care unit between June 1st, 2020 and October 1st 2022 were retrospectively evaluated. The air column area of the trachea was measured and the effect of the values obtained on mortality and length of stay in the intensive care unit for patients COVID-19 was examined.Results: We found that an increase in the mean tracheal air column increased mortality by 1.218 times. We also determined that an increase in the mean area of the tracheal air column increased the length of stay in the intensive care unit. Furthermore, we showed that advanced age and an increase in the length of stay in the intensive care unit were factors that increased mortality.Conclusion: Tracheomegaly is a poor prognostic factor in COVID-19 disease and is easily diagnosed with CT.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126846590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Stroke remains a massive public health burden, affecting approximately 795,000 individuals each year. It is the leading cause of long-term disability in adults and the third leading cause of death in developed countries. After a stroke, medical complications are common and can prolong hospital stay, worsen stroke outcomes, and increase the cost of care. The most common medical complications related to stroke are infections, including pneumonia and urinary tract infection (UTI). Intervention strategies previously investigated in these cases and other patient populations include prophylactic antibiotics, antiseptic-impregnated catheters, and quality improvement interventions to reduce inappropriate catheterization. In addition, in recent years, complementary and alternative medicine methods, such as Melaleuca viridiflora (also known as tea tree or Niaouli oil) have become increasingly popular. The primary uses of this oil have historically been associated with the antiseptic and anti-inflammatory effects of this plant. In this study, we investigated the efficacy of M. viridiflora (Niaouli) oil in the treatment of UTIs in stroke patients.Material and Method: We did not find any study in the literature on the effects of Niaouli aromatherapeutic oil on UTIs, which are common in hemiplegic patients; therefore, we planned the current study. The hospital records were screened to identify patients treated at the Physical Therapy and Rehabilitation Unit of Health Sciences University Adana City Training and Research Hospital, who were diagnosed with UTIs during their follow-up and recommended Niaouli aromatherapy oil as a complementary treatment. The oil was supplied by the patients themselves. As the method of use, the patients were asked to prepare a washing solution by dripping 10 drops of Niaouli oil into 1 liter of water. The patients were recommended to wash the perineum area three times a day with this solution for 20 days.Results: The mean age of the hemiplegic patients evaluated in the study was 51.55±19.20 (min=18, max=77) years. Of the patients, 72.7% were male, 42.4% had an American Spinal Injury Association classification of C, 54.5% had spontaneous bladder emptying, and 30.3% had stage 1, 21.1% had stage 2, and 3.0% had stage 3 spasticity. Leukocyte esterase and leukocyte in urine and sedimentation values statistically significantly decreased in the post-treatment period compared to the pre-treatment period.Conclusion: UTI is a common complication in stroke patients. In this study, it was determined that the efficacy of the treatment of UTIs increased, and the use of antibiotics significantly decreased with the utilization of the fungicidal and bactericidal effects of M. viridiflora (Niaouli) aromatherapy oil.
{"title":"Could niaouli aromatherapy oil be an option in the treatment of urinary tract infections in hemiplegic patients?","authors":"Nilüfer Aygün Bilecik, Gülşah YAŞA ÖZTÜRK","doi":"10.38053/acmj.1227991","DOIUrl":"https://doi.org/10.38053/acmj.1227991","url":null,"abstract":"Aim: Stroke remains a massive public health burden, affecting approximately 795,000 individuals each year. It is the leading cause of long-term disability in adults and the third leading cause of death in developed countries. After a stroke, medical complications are common and can prolong hospital stay, worsen stroke outcomes, and increase the cost of care. The most common medical complications related to stroke are infections, including pneumonia and urinary tract infection (UTI). Intervention strategies previously investigated in these cases and other patient populations include prophylactic antibiotics, antiseptic-impregnated catheters, and quality improvement interventions to reduce inappropriate catheterization. In addition, in recent years, complementary and alternative medicine methods, such as Melaleuca viridiflora (also known as tea tree or Niaouli oil) have become increasingly popular. The primary uses of this oil have historically been associated with the antiseptic and anti-inflammatory effects of this plant. In this study, we investigated the efficacy of M. viridiflora (Niaouli) oil in the treatment of UTIs in stroke patients.Material and Method: We did not find any study in the literature on the effects of Niaouli aromatherapeutic oil on UTIs, which are common in hemiplegic patients; therefore, we planned the current study. The hospital records were screened to identify patients treated at the Physical Therapy and Rehabilitation Unit of Health Sciences University Adana City Training and Research Hospital, who were diagnosed with UTIs during their follow-up and recommended Niaouli aromatherapy oil as a complementary treatment. The oil was supplied by the patients themselves. As the method of use, the patients were asked to prepare a washing solution by dripping 10 drops of Niaouli oil into 1 liter of water. The patients were recommended to wash the perineum area three times a day with this solution for 20 days.Results: The mean age of the hemiplegic patients evaluated in the study was 51.55±19.20 (min=18, max=77) years. Of the patients, 72.7% were male, 42.4% had an American Spinal Injury Association classification of C, 54.5% had spontaneous bladder emptying, and 30.3% had stage 1, 21.1% had stage 2, and 3.0% had stage 3 spasticity. Leukocyte esterase and leukocyte in urine and sedimentation values statistically significantly decreased in the post-treatment period compared to the pre-treatment period.Conclusion: UTI is a common complication in stroke patients. In this study, it was determined that the efficacy of the treatment of UTIs increased, and the use of antibiotics significantly decreased with the utilization of the fungicidal and bactericidal effects of M. viridiflora (Niaouli) aromatherapy oil.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129115869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Özsoy, S. Cesur, Ç. Ataman Hatipoğlu, Ş. Erdinç, Günay Tuncer Ertem, S. Kınıklı
Aim: COVID-19 is an important public health problem in world and Turkey. The present study aimed to compare the clinical and laboratory findings and mortality rates among vaccinated and unvaccinated COVID-19 inpatients.Material and Method: We included patients receiving inpatient treatment in COVID-19 wards of our hospital between April 25 and October 22, 2021. The patients were divided into two groups: those with and without the COVID-19 vaccine. We extracted patient information from anamnesis files and the hospital information system. Then, we recorded the patients’ epidemiological and laboratory findings and vaccination status. Patients with at least two doses of the COVID-19 vaccine were considered “vaccinated.” We performed Fisher’s exact test and Chi-square test to analyze the data. All statistical analyses were performed in SPSS, and a p-value <0.05 was accepted as statistically significant.Results: The study included 63 vaccinated and 83 unvaccinated patients. With a mean age of 71.4±12.3 years, thirty (47.6%) of the vaccinated patients were females, and 33 (52.3%) were males. Of the unvaccinated ones, 40 (48.1%) were females, while 43 (51.8%) were males (mean age=52.2±14.4 years). The mean age was significantly higher in the vaccinated group than in the unvaccinated group (p<0.01). While 82.5% of the vaccinated patients received two doses, 17.5% received three doses of the COVID vaccine. Besides, 95.3% of the patients received their first dose of inactivated vaccine (Sinovac, China) and 4.7% of an mRNA vaccine (BioNTech, Germany). We found that comorbidities were significantly more prevalent in the vaccinated group than in the unvaccinated group (44 (69.8%) vaccinated and 34 (40.9%) unvaccinated patients had a comorbid disease, p<0.01). Among the accompanying diseases, hypertension was significantly more prevalent in the vaccinated group than in the unvaccinated group (p<0.01). Considering their laboratory findings, the vaccinated patients had significantly higher leukocyte, troponin, and ferritin values than the unvaccinated patients (p=0.008). Consequently, five (57.9) of the vaccinated patients and 4 (4.8%) of the unvaccinated patients died (p=0.05). Conclusion: Similar mortality rates between our vaccinated and unvaccinated patients may be attributed to the fact that the vaccinated group was relatively older, had more comorbid diseases, and received their second dose after an average of 100.6 days following their first dose of inactivated vaccine. In conclusion, further clinical research involving more cases that received different COVID-19 vaccines is needed to uncover the factors affecting mortality and morbidity among vaccinated patients.
{"title":"Investigating clinical and laboratory findings and mortality rates among vaccinated and unvaccinated COVID-19 inpatients","authors":"M. Özsoy, S. Cesur, Ç. Ataman Hatipoğlu, Ş. Erdinç, Günay Tuncer Ertem, S. Kınıklı","doi":"10.38053/acmj.1218224","DOIUrl":"https://doi.org/10.38053/acmj.1218224","url":null,"abstract":"Aim: COVID-19 is an important public health problem in world and Turkey. The present study aimed to compare the clinical and laboratory findings and mortality rates among vaccinated and unvaccinated COVID-19 inpatients.Material and Method: We included patients receiving inpatient treatment in COVID-19 wards of our hospital between April 25 and October 22, 2021. The patients were divided into two groups: those with and without the COVID-19 vaccine. We extracted patient information from anamnesis files and the hospital information system. Then, we recorded the patients’ epidemiological and laboratory findings and vaccination status. Patients with at least two doses of the COVID-19 vaccine were considered “vaccinated.” We performed Fisher’s exact test and Chi-square test to analyze the data. All statistical analyses were performed in SPSS, and a p-value <0.05 was accepted as statistically significant.Results: The study included 63 vaccinated and 83 unvaccinated patients. With a mean age of 71.4±12.3 years, thirty (47.6%) of the vaccinated patients were females, and 33 (52.3%) were males. Of the unvaccinated ones, 40 (48.1%) were females, while 43 (51.8%) were males (mean age=52.2±14.4 years). The mean age was significantly higher in the vaccinated group than in the unvaccinated group (p<0.01). While 82.5% of the vaccinated patients received two doses, 17.5% received three doses of the COVID vaccine. Besides, 95.3% of the patients received their first dose of inactivated vaccine (Sinovac, China) and 4.7% of an mRNA vaccine (BioNTech, Germany). We found that comorbidities were significantly more prevalent in the vaccinated group than in the unvaccinated group (44 (69.8%) vaccinated and 34 (40.9%) unvaccinated patients had a comorbid disease, p<0.01). Among the accompanying diseases, hypertension was significantly more prevalent in the vaccinated group than in the unvaccinated group (p<0.01). Considering their laboratory findings, the vaccinated patients had significantly higher leukocyte, troponin, and ferritin values than the unvaccinated patients (p=0.008). Consequently, five (57.9) of the vaccinated patients and 4 (4.8%) of the unvaccinated patients died (p=0.05). Conclusion: Similar mortality rates between our vaccinated and unvaccinated patients may be attributed to the fact that the vaccinated group was relatively older, had more comorbid diseases, and received their second dose after an average of 100.6 days following their first dose of inactivated vaccine. In conclusion, further clinical research involving more cases that received different COVID-19 vaccines is needed to uncover the factors affecting mortality and morbidity among vaccinated patients.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114402096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: This study aimed to investigate how the mental tension and environmental conditions caused by the COVID-19 pandemic affected the alcohol and substance use habits of university students and the changes in the rates of antidepressant drug use for mood disorders due to the pandemic.Material and Method: This cross-sectional survey study was conducted using an electronic survey completed by university students in Turkey between the years 2021-2022. Our study consisted of a questionnaire prepared to collect the demographic information of the participants and the Bapirt-Alcohol/Substance scale used to determine alcohol/substance addiction level. The survey, which took 5 minutes to complete, was randomly distributed to university students.Results: A total of 641 participants, approximately 66% female and 34% male, between the ages of 18 and 41 years were included in the study. The mean alcohol dependence scores before and during the COVID-19 pandemic were 0.91 and 1.35 and substance addiction scores were found to be 0.17 and 0.33. There was a significant difference in the average alcohol and substance addiction scores of the students during the pandemic compared to the pre-pandemic period (for alcohol addiction: p=0.000; for substance addiction: p=0.007). Students who perceived their income level as mostly low had significantly higher alcohol addiction scores during the pandemic period compared to pre-COVID-19 (p=0.014). Compared to the pre-pandemic period, the average alcohol and substance addiction scores were found to be significantly higher in students residing in dormitories/student houses during the pandemic period (p=0.014 for alcohol; p=0.001 for substances). Antidepressant drug use rates of the participants were found to be higher during the pandemic period compared to the pre-pandemic period.Conclusion: As a result of this study, when the addiction levels for alcohol and substance use in university students before the COVID-19 pandemic and during the pandemic were compared, addiction increased in general. The prevalence of depression increased due to changing lifestyles and disruptions as a result of the pandemic, and accordingly, serious increases were observed in the use of antidepressant drugs.
{"title":"Evaluation of alcohol, substance and antidepressant drug use of university students during the COVID-19 pandemic","authors":"Cem Bulgan, G. Demirel","doi":"10.38053/acmj.1169944","DOIUrl":"https://doi.org/10.38053/acmj.1169944","url":null,"abstract":"Aim: This study aimed to investigate how the mental tension and environmental conditions caused by the COVID-19 pandemic affected the alcohol and substance use habits of university students and the changes in the rates of antidepressant drug use for mood disorders due to the pandemic.Material and Method: This cross-sectional survey study was conducted using an electronic survey completed by university students in Turkey between the years 2021-2022. Our study consisted of a questionnaire prepared to collect the demographic information of the participants and the Bapirt-Alcohol/Substance scale used to determine alcohol/substance addiction level. The survey, which took 5 minutes to complete, was randomly distributed to university students.Results: A total of 641 participants, approximately 66% female and 34% male, between the ages of 18 and 41 years were included in the study. The mean alcohol dependence scores before and during the COVID-19 pandemic were 0.91 and 1.35 and substance addiction scores were found to be 0.17 and 0.33. There was a significant difference in the average alcohol and substance addiction scores of the students during the pandemic compared to the pre-pandemic period (for alcohol addiction: p=0.000; for substance addiction: p=0.007). Students who perceived their income level as mostly low had significantly higher alcohol addiction scores during the pandemic period compared to pre-COVID-19 (p=0.014). Compared to the pre-pandemic period, the average alcohol and substance addiction scores were found to be significantly higher in students residing in dormitories/student houses during the pandemic period (p=0.014 for alcohol; p=0.001 for substances). Antidepressant drug use rates of the participants were found to be higher during the pandemic period compared to the pre-pandemic period.Conclusion: As a result of this study, when the addiction levels for alcohol and substance use in university students before the COVID-19 pandemic and during the pandemic were compared, addiction increased in general. The prevalence of depression increased due to changing lifestyles and disruptions as a result of the pandemic, and accordingly, serious increases were observed in the use of antidepressant drugs.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125036208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Kekilli, Ebru Atasever Akkas, Serab Uyar, E. Yekedüz
Aim: Systemic immune-inflammation indexes have been reported to be associated with clinical outcomes in several malignancies. Herein, we aimed to evaluate the potential relationship between prognostic nutritional index (PNI), systemic immune-inflammation index (SII), the neutrophil- to- lymphocyte ratio (NLR), the monocyte- to- lymphocyte ratio (MLR), the platelet-to-lymphocyte ratio (PLR) and the treatment response in patients with esophageal cancer who underwent neoadjuvant chemoradiotherapy (CRT).Material and Method: Esophageal cancer (EC) patients who underwent neoadjuvant CRT were retrospectively enrolled in the study. Immune-inflammation indexes were calculated from pretreatment blood counts in samples obtained. The relationships between PNI, SII, NLR, MLR, PLR values, treatment response, and overall survival (OS) rates were examined.Results: The data of 103 patients with EC who were referred to the Radiation Oncology Clinic of Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital were retrospectively analyzed. In the univariate analysis for OS, alcohol consumption, CRT agent, NLR, MLR, PLR, SII and PNI were found as prognostic factors. Also alcohol consumption was found as an independent prognostic factor in multivariate analyzes (HR:5.201, 95% CI:1.9-14.2, p=0.01). Conclusion: In our study, high SII and low PNI values were not found to be independent poor prognostic factors for OS, but lower OS rates were observed in patients with high SII and low PNI values.
{"title":"The relationship between systemic immune-inflammation indexes and treatment response in locally advanced esophageal cancer","authors":"E. Kekilli, Ebru Atasever Akkas, Serab Uyar, E. Yekedüz","doi":"10.38053/acmj.1208368","DOIUrl":"https://doi.org/10.38053/acmj.1208368","url":null,"abstract":"Aim: Systemic immune-inflammation indexes have been reported to be associated with clinical outcomes in several malignancies. Herein, we aimed to evaluate the potential relationship between prognostic nutritional index (PNI), systemic immune-inflammation index (SII), the neutrophil- to- lymphocyte ratio (NLR), the monocyte- to- lymphocyte ratio (MLR), the platelet-to-lymphocyte ratio (PLR) and the treatment response in patients with esophageal cancer who underwent neoadjuvant chemoradiotherapy (CRT).Material and Method: Esophageal cancer (EC) patients who underwent neoadjuvant CRT were retrospectively enrolled in the study. Immune-inflammation indexes were calculated from pretreatment blood counts in samples obtained. The relationships between PNI, SII, NLR, MLR, PLR values, treatment response, and overall survival (OS) rates were examined.Results: The data of 103 patients with EC who were referred to the Radiation Oncology Clinic of Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital were retrospectively analyzed. In the univariate analysis for OS, alcohol consumption, CRT agent, NLR, MLR, PLR, SII and PNI were found as prognostic factors. Also alcohol consumption was found as an independent prognostic factor in multivariate analyzes (HR:5.201, 95% CI:1.9-14.2, p=0.01). Conclusion: In our study, high SII and low PNI values were not found to be independent poor prognostic factors for OS, but lower OS rates were observed in patients with high SII and low PNI values. ","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125954230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: The objective of the present study is to increase nurses’ awareness of delirium risk factors, make nurses gain competence in using Nursing Delirium Screening Scale (Nu-DESC), and improve the quality of care by detecting delirium early in intensive care unit patients.Material and Method: The research is a descriptive and correlational study. The sample consisted of 55 patients in an intensive care unit. Data of the study was collected with the Personal Information Form, the Richmond Agitation and Sedation Scale, the Glasgow Coma Scale, and the Nu-DESC.Results: The majority of patients (89%) demonstrated the symptoms of anxiety and agitation. There was a significant correlation between age and the day delirium was detected and the Nu-DESC. In the study, isolation need, ventilator support, and pain were determined as risk factors. Conclusion: The results of the study revealed the necessity of using measurement tools for the early detection of delirium in clinical practice by nurses.
{"title":"Determination of the risk factors and delirium in the intensive care unit","authors":"A. Bahar, Mina Güner","doi":"10.38053/acmj.1178278","DOIUrl":"https://doi.org/10.38053/acmj.1178278","url":null,"abstract":"Aim: The objective of the present study is to increase nurses’ awareness of delirium risk factors, make nurses gain competence in using Nursing Delirium Screening Scale (Nu-DESC), and improve the quality of care by detecting delirium early in intensive care unit patients.Material and Method: The research is a descriptive and correlational study. The sample consisted of 55 patients in an intensive care unit. Data of the study was collected with the Personal Information Form, the Richmond Agitation and Sedation Scale, the Glasgow Coma Scale, and the Nu-DESC.Results: The majority of patients (89%) demonstrated the symptoms of anxiety and agitation. There was a significant correlation between age and the day delirium was detected and the Nu-DESC. In the study, isolation need, ventilator support, and pain were determined as risk factors. Conclusion: The results of the study revealed the necessity of using measurement tools for the early detection of delirium in clinical practice by nurses.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121231943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Tubal reversal is the surgery done after tubal sterilization. Mostly, sterilization at a younger age or a new partner makes women request tubal reanastomosis. In the literature, pregnancy and ectopic pregnancy rates after tubal reversal is about 65% and 5.6%, respectively.Material and Method: In our study, data from the files of patients who had tubal reversal operations between 2015-2021 years in Sanliurfa Training and Research Hospital were collected retrospectively. Demographic features, surgical and pregnancy outcome data of patients were collected. This study investigated the pregnancy rates and associated factors with pregnancy rates after tubal reanastomosis operations. Results: In our study, 112 patients with tubal reversal operations were recorded. 25 out of 112 patients had spontaneous pregnancy after the tubal reversal operation. Age at a tubal reversal was a significantly important factor between a pregnant and non-pregnant group. According to age, below 40 years seems an ideal age factor for pregnancy. In our study, pregnancy rates were lower than in the literature.Conclusion: Tubal reversal operation can be an alternative to IVF below 40 years of age.
{"title":"Can tubal reversal be an alternative to IVF? Cohort study","authors":"Alev Esercan, E. Ekmekci","doi":"10.38053/acmj.1179603","DOIUrl":"https://doi.org/10.38053/acmj.1179603","url":null,"abstract":"Introduction: Tubal reversal is the surgery done after tubal sterilization. Mostly, sterilization at a younger age or a new partner makes women request tubal reanastomosis. In the literature, pregnancy and ectopic pregnancy rates after tubal reversal is about 65% and 5.6%, respectively.Material and Method: In our study, data from the files of patients who had tubal reversal operations between 2015-2021 years in Sanliurfa Training and Research Hospital were collected retrospectively. Demographic features, surgical and pregnancy outcome data of patients were collected. This study investigated the pregnancy rates and associated factors with pregnancy rates after tubal reanastomosis operations. Results: In our study, 112 patients with tubal reversal operations were recorded. 25 out of 112 patients had spontaneous pregnancy after the tubal reversal operation. Age at a tubal reversal was a significantly important factor between a pregnant and non-pregnant group. According to age, below 40 years seems an ideal age factor for pregnancy. In our study, pregnancy rates were lower than in the literature.Conclusion: Tubal reversal operation can be an alternative to IVF below 40 years of age.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122488912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Dal, Esra Sultan Karabulut Keklik, G. Dagtekin, Eda Yaman, Polat Pehlivanoğlu, Meltem Çimen, S. Diker, M. Avcil, S. Avci
Aim: In patients with Coronavirus disease 2019 (COVID-19) infection, a situation called cytokine storm and an increase in proinflammatory cytokines such as interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-1 (IL-1) in the blood has been observed and it has been found that this is clinically related to the development of severe disease. Therefore, tocilizumab (TCZ) therapy that blocks IL-6 will reduce the immunological response and thus potentially harm caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The aim of this study is to determine the effect of TCZ treatment on length of hospital stay, need for invasive mechanical ventilation and mortality in COVID-19 patients followed in the tertiary intensive care unit.Material and Method: This retrospective cross-sectional study was conducted among patients hospitalized with the diagnosis of COVID-19 pneumonia between 01.09.2020 and 01.01.21 in intensive care units. Data were analyzed and evaluated separately in patients who received and did not receive TCZ treatment. Patients older than 18 years of age, who were hospitalized for at least 24 hours with the diagnosis of COVID-19 pneumonia and needed ≥36 hours of oxygen therapy, were not referred to another health center, were included in this study. Pregnant and lactating women were not included in the study. Patients with missing at least one data in the parameters to be evaluated were excluded from the study. Patients treated with an IL-6 inhibitor other than TCZ were excluded.Results: After excluding patients who did not meet the inclusion criteria, 565 patients were included in the study. It was found that patients who received TCZ treatment after propensity score matching (PSM) had a significantly higher mean age (P<0.001) and lower obesity rates (P=0.002). There was no significant difference between the patients who received and did not receive TCZ treatment in terms of mechanical ventilation need, length of hospital stay and mortality (P=0.505, P=0.661, P=0.834).Conclusion: As a result of our research, it was seen that TCZ treatment did not affect the need for invasive mechanical ventilation, hospital and intensive care unit stay, and mortality.
{"title":"Comparison of clinical outcomes of intensive care patients with COVID-19 pneumonia receiving and not receiving tocilizumab treatment","authors":"H. Dal, Esra Sultan Karabulut Keklik, G. Dagtekin, Eda Yaman, Polat Pehlivanoğlu, Meltem Çimen, S. Diker, M. Avcil, S. Avci","doi":"10.38053/acmj.1198167","DOIUrl":"https://doi.org/10.38053/acmj.1198167","url":null,"abstract":"Aim: In patients with Coronavirus disease 2019 (COVID-19) infection, a situation called cytokine storm and an increase in proinflammatory cytokines such as interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-1 (IL-1) in the blood has been observed and it has been found that this is clinically related to the development of severe disease. Therefore, tocilizumab (TCZ) therapy that blocks IL-6 will reduce the immunological response and thus potentially harm caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The aim of this study is to determine the effect of TCZ treatment on length of hospital stay, need for invasive mechanical ventilation and mortality in COVID-19 patients followed in the tertiary intensive care unit.Material and Method: This retrospective cross-sectional study was conducted among patients hospitalized with the diagnosis of COVID-19 pneumonia between 01.09.2020 and 01.01.21 in intensive care units. Data were analyzed and evaluated separately in patients who received and did not receive TCZ treatment. Patients older than 18 years of age, who were hospitalized for at least 24 hours with the diagnosis of COVID-19 pneumonia and needed ≥36 hours of oxygen therapy, were not referred to another health center, were included in this study. Pregnant and lactating women were not included in the study. Patients with missing at least one data in the parameters to be evaluated were excluded from the study. Patients treated with an IL-6 inhibitor other than TCZ were excluded.Results: After excluding patients who did not meet the inclusion criteria, 565 patients were included in the study. It was found that patients who received TCZ treatment after propensity score matching (PSM) had a significantly higher mean age (P<0.001) and lower obesity rates (P=0.002). There was no significant difference between the patients who received and did not receive TCZ treatment in terms of mechanical ventilation need, length of hospital stay and mortality (P=0.505, P=0.661, P=0.834).Conclusion: As a result of our research, it was seen that TCZ treatment did not affect the need for invasive mechanical ventilation, hospital and intensive care unit stay, and mortality.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127008895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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