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MALNUTRITION AT HOSPITAL ADMISSION AND ITS ASSOCIATED FACTORS IN INTERNAL MEDICINE INPATIENTS 内科住院患者入院时营养不良及其相关因素
Pub Date : 2023-06-24 DOI: 10.14710/jgi.11.2.128-139
Wita Rizki Amelia, Astrine Permata Leoni, A. Syauqy, P. Laksmi, Martalena Br Purba, E. Noer, Lora Sri Nofi, Befi Sundari, Mita Arini
ABSTRACTBackground: Malnutrition at hospital admission may adversely affect patients' clinical outcomes. The Global Leadership Initiative on Malnutrition (GLIM) recently set a standard of measurable criteria to diagnose malnutrition. Objectives: This study aimed to determine the proportion and risk factors of malnutrition at hospital admission.Materials and Methods: A cross-sectional observational study was conducted in the internal medicine ward of the National General Central Hospital, Dr. Cipto Mangunkusmo (RSCM), Jakarta, from January to May 2022. Subjects aged 18 and above were recruited for this study. Malnutrition at hospital admission was defined according to the GLIM criteria. Then, the data were analyzed using multiple logistic regression to determine malnutrition risk factors, presented by odds ratios (OR) and 95% confidence intervals (CI).Results: A total of 231 subjects were enrolled in the study. Among them, 85.3% were malnourished according to the GLIM criteria. In addition, subjects with a severe to total dependency on functional status (OR 9.406, 95%CI: 3.147–28.109), inadequate energy intake (OR 2.718, 95%CI: 1.197–6.172), and multimorbidity (OR 2.337, 95%CI: 1.045–5.228), were significantly associated with malnutrition at hospital admission cases. Conclusion: According to the GLIM criteria, the proportion of malnutrition at hospital admission is high. The risk factors of malnutrition at hospital admission include low functional status, inadequate energy intake, and multimorbidity.Keywords : Malnutrition; Nutritional status; Nutrition assessment; Hospital admission; Internal medicine, Inpatients
摘要背景:住院时的营养不良可能会影响患者的临床预后。全球营养不良领导倡议(GLIM)最近制定了一套可衡量的诊断营养不良标准。目的:本研究旨在确定住院时营养不良的比例和危险因素。材料和方法:横断面观察研究于2022年1月至5月在雅加达国家综合中心医院Cipto Mangunkusmo博士(RSCM)内科病房进行。研究对象年龄在18岁及以上。住院时的营养不良是根据GLIM标准定义的。然后,对数据进行多元logistic回归分析,以比值比(OR)和95%置信区间(CI)确定营养不良的危险因素。结果:共有231名受试者入组。根据GLIM标准,其中85.3%为营养不良。此外,严重到完全依赖功能状态的受试者(OR 9.406, 95%CI: 3.147-28.109)、能量摄入不足(OR 2.718, 95%CI: 1.197-6.172)和多病(OR 2.337, 95%CI: 1.045-5.228)与住院病例营养不良显著相关。结论:根据GLIM标准,住院患者营养不良比例较高。住院时营养不良的危险因素包括功能低下、能量摄入不足和多发病。关键词:营养不良;营养状况;营养评估;住院;内科,住院病人
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引用次数: 0
ASSOCIATION OF EATING HABITS AND COOKING METHODS WITH BREAST TUMORS AMONG CHILDBEARING AGED URBAN WOMEN IN INDONESIA: A CROSS-SECTIONAL STUDY 印度尼西亚育龄城市妇女的饮食习惯和烹饪方法与乳腺肿瘤的关系:一项横断面研究
Pub Date : 2023-06-24 DOI: 10.14710/jgi.11.2.85-94
Imaviana Cahyani, Khairizka Citra Palupi, Adi Kurniawan, Leffiyanti Handi, Rathi Paramastri, Mertien Sa’pang
ABSTRACTBackground: breast tumors is the single most commonly detected benign or malignant tumors among women and has now become a global health burden.Objective: This study aimed to determine the associations of eating habits and cooking methods with a breast tumor in childbearing-aged Indonesian urban women.Materials and Methods: This was a cross-sectional study using a community survey of research of non-communicable disease 2016 database from the ministry of health of Indonesia. In total,28558 women, aged 25 – 49 years old were retrieved from the database. Eating habits and cooking methods were measured using a validated food frequency questionnaire. A forward logistic regression analysis was used to examine the association of eating habits and cooking methods with the risk of breast tumors.Results: Higher education level was positively associated with the incidence of breast tumors (OR = 1.10, 95%CI: 1.01-1.20, p = 0.026). Seafood (OR = 0.88, 95% CI: 0.80-0.96, p = 0.006) and fast foods (OR = 1.10, 95% CI: 1.00-1.20, p = 0.049) were associated with the incidence of breast tumor among urban women. Roasted/smoked cooking method was positively associated with risk of breast tumor (OR = 1.27, 95%CI: 1.01 – 1.61, p = 0.043).Conclusion: Our study is the first community-based study in Indonesia investigating the association of eating habits and cooking methods with the incidence of breast tumors among childbearing-aged urban women. High intake of seafood was associated with a lower risk of breast tumors, while fast foods and roasted/smoked cooking method belief to have a detrimental effect on a breast tumor. Prospective studies are needed to confirm the present study findings.Keywords : eating habits, cooking methods, breast tumor, urban women
摘要背景:乳腺肿瘤是女性中最常见的良性或恶性肿瘤,现已成为全球性的健康负担。目的:本研究旨在确定印度尼西亚育龄城市妇女的饮食习惯和烹饪方法与乳腺肿瘤的关系。材料和方法:这是一项横断面研究,使用印度尼西亚卫生部2016年非传染性疾病研究社区调查数据库。总共从数据库中检索了28558名年龄在25 - 49岁之间的女性。饮食习惯和烹饪方法使用有效的食物频率问卷进行测量。采用前瞻性逻辑回归分析来检验饮食习惯和烹饪方法与乳腺肿瘤风险之间的关系。结果:高学历与乳腺肿瘤发病率呈正相关(OR = 1.10, 95%CI: 1.01 ~ 1.20, p = 0.026)。海鲜(OR = 0.88, 95% CI: 0.80-0.96, p = 0.006)和快餐(OR = 1.10, 95% CI: 1.00-1.20, p = 0.049)与城市女性乳腺癌发病率相关。烤/烟熏烹饪方式与乳腺癌发病风险呈正相关(OR = 1.27, 95%CI: 1.01 ~ 1.61, p = 0.043)。结论:我们的研究是印度尼西亚第一个以社区为基础的研究,旨在调查育龄城市妇女的饮食习惯和烹饪方法与乳腺肿瘤发病率之间的关系。大量摄入海鲜与患乳腺肿瘤的风险较低有关,而快餐和烤/烟熏烹饪方法被认为对患乳腺肿瘤有有害影响。需要前瞻性研究来证实目前的研究结果。关键词:饮食习惯,烹饪方法,乳腺肿瘤,城市女性
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引用次数: 0
SMALL DENSE LOW-DENSITY LIPOPROTEIN CHOLESTEROL AND CENTRAL OBESITY ASSOCIATED WITH DIABETES MELLITUS AMONG INDONESIAN ADULTS 印度尼西亚成人中小密度低密度脂蛋白胆固醇和中心性肥胖与糖尿病相关
Pub Date : 2023-06-24 DOI: 10.14710/jgi.11.2.95-109
Yeni Rohmaeni, Hardinsyah Hardinsyah, I. Tanziha
ABSTRACTBackground: Small dense low-density lipoprotein (sdLDL-C) is an atherogenic lipoprotein. Increased sdLDL-C concentration was hypothesized to be associated with obesity and diabetes mellitus (DM).Objectives: The study aimed to determine the association between sdLDL-C, central obesity, and DM among Indonesian adults, controlled by personal and clinical parameters.Materials and Methods: This study used secondary data from Basic Health Research 2013 of the Ministry of Health, which applied a cross-sectional study design. For this purpose, 30,548 subjects aged 19-79 were analyzed. The sdLDL-C was performed by using Sampson Formula derived from conventional lipid panels. As investigated by Sampson, the formula referred to cLDL-C (calculated LDL-C) and ElbLDL-C (estimated large buoyant LDL-C).Results: There was a positive association between sdLDL-C and central obesity (OR: 3.94; 95% CI: 3.13-3.89), as well as sdLDL-C and DM status (OR: 1.98; 95% CI; 1.43-2.75) after adjusting the personal and clinical parameters.Conclusion: This study demonstrated that the increment of sdLDL-C level and central obesity affected DM status in Indonesian adults. It implies that the sdLDL-C was a potential biomarker to assess the risk of DM.Keywords: Central obesity, Diabetes mellitus, Hypertension, Indonesian adult, sdLDL-C 
摘要背景:小密度低密度脂蛋白(sdLDL-C)是一种致动脉粥样硬化的脂蛋白。sdLDL-C浓度升高被认为与肥胖和糖尿病(DM)有关。目的:本研究旨在通过个人和临床参数控制,确定印尼成年人中sdLDL-C、中心性肥胖和糖尿病之间的关系。材料与方法:本研究使用的二手数据来自卫生部《基础卫生研究2013》,采用横断面研究设计。为此,我们分析了30,548名年龄在19-79岁之间的受试者。sdLDL-C采用常规脂质板衍生的Sampson公式测定。根据Sampson的研究,该公式指的是cLDL-C(计算LDL-C)和ElbLDL-C(估计大浮力LDL-C)。结果:sdLDL-C与中心性肥胖呈正相关(OR: 3.94;95% CI: 3.13-3.89),以及sdLDL-C和DM状态(OR: 1.98;95%可信区间;1.43-2.75),调整个人和临床参数后。结论:本研究表明,sdLDL-C水平的升高和中心性肥胖影响印度尼西亚成年人的糖尿病状态。提示sdLDL-C是评估糖尿病风险的潜在生物标志物。关键词:中心性肥胖,糖尿病,高血压,印尼成人,sdLDL-C
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引用次数: 0
STUDY OF VITAMIN D3-FORTIFIED GOAT KEFIR ON PLASMA FIBRINOGEN LEVELS OF DIABETIC RATTUS NORVEGICUS RATS 维生素d3强化山羊开菲尔对糖尿病褐家鼠血浆纤维蛋白原水平的影响
Pub Date : 2023-06-24 DOI: 10.14710/jgi.11.2.77-84
Tania Masha, Astika Widy Utomo, M. Ardiaria, A. Syauqy, A. Rahadiyanti, C. Nissa, Mutiara Irma Maharani, Fairuz Zulfa, B. Panunggal
ABSTRACTBackground: Diabetes mellitus is often associated with the occurrence of complications. Haemostatic factors, especially hyperfibrinogenaemia, is a common cause of the complication. Goat kefir and vitamin D3 may act as an antioxidant and anti-inflammation agent which can repair pancreatic beta cells.Objectives: This study aimed to analyse the effect of vitamin D3-fortified goat milk and plasma fibrinogen levels in diabetic rats. Materials and Methods: This study was an experimental study with pre-post only group design. The samples were 21 male rats divided into four groups; negative control (K-), positive control (K +), treated with unfortified goat kefir (P1), and treated with vitamin D3-fortified goat kefir (P2). The 35-day intervention was conducted, the goat kefir dose was 2 ml/200 g BW/day and the vitamin D dose 600 IU. Fasting blood glucose and plasma fibrinogen were assessed pre- and post-intervention. Blood glucose level was evaluated by GOD-PAP method, while plasma fibrinogen was assessed by Enzyme-Linked Immunosorbent Assay (ELISA) method. The data were analysed with paired t-test and One-Way ANOVA. Results: There were not significant difference levels of fibrinogen between groups. The intervention groups both showed an insignificant decrease of plasma fibrinogen. The plasma fibrinogen of group treated with vitamin D3-fortified goat kefir went down to 13.47 mg/dl from 16.49 mg/dl (p = 0.49). Meanwhile, the group treated with unfortified goat kefir showed a decrease from 26.81 mg/dl to 24.94 mg/dl (p=0.83). On the other hand, there was a significant decrease in fasting blood glucose in the group treated with vitamin D3-fortified goat kefir from 181.75 mg/dl to 116.25 mg/dl (p=0.03).Conclusion Our results demonstrate that administration of vitamin D3-fortified goat kefir can decrease fasting blood glucose but not in plasma fibrinogen. Keywords : Diabetes Mellitus; Fastin blood glucose; Fibrinogen; Goat kefir; Vitamin D3 Fortification 
摘要背景:糖尿病常与并发症的发生有关。止血因子,特别是高纤维蛋白原血症,是并发症的常见原因。山羊开菲尔和维生素D3可以作为一种抗氧化剂和抗炎症剂,可以修复胰腺细胞。目的:探讨维生素d3强化羊奶对糖尿病大鼠血浆纤维蛋白原水平的影响。材料与方法:本研究为实验研究,采用前-后单组设计。样本为21只雄性大鼠,分为四组;阴性对照(K-)、阳性对照(K +),分别用未加维生素d3的山羊开菲尔处理(P1)和加维生素d3的山羊开菲尔处理(P2)。进行35天的干预,山羊开菲尔剂量为2 ml/200 g BW/天,维生素D剂量为600 IU。干预前后分别评估空腹血糖和血浆纤维蛋白原。采用GOD-PAP法测定血糖水平,ELISA法测定血浆纤维蛋白原。数据分析采用配对t检验和单因素方差分析。结果:两组间纤维蛋白原水平无显著性差异。干预组血浆纤维蛋白原水平均无明显下降。维生素d3强化山羊开菲尔组血浆纤维蛋白原由16.49 mg/dl降至13.47 mg/dl (p = 0.49)。与此同时,未经强化的山羊开菲尔组从26.81 mg/dl降至24.94 mg/dl (p=0.83)。另一方面,服用维生素d3强化山羊开菲尔组的空腹血糖从181.75 mg/dl显著降低到116.25 mg/dl (p=0.03)。结论添加维生素d3的山羊开菲尔能降低空腹血糖,但不能降低血浆纤维蛋白原。关键词:糖尿病;空腹血糖;纤维蛋白原;山羊酸乳酒;维生素D3强化
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引用次数: 0
DETERMINING THE NUTRIENTS CHANGES AFTER UNDERGOING NUTRITIONAL COUNSELING AND COOKING ASSISTANCE AMONG T2DM OUTPATIENTS IN MALANG CITY, INDONESIA 确定印尼玛琅市2型糖尿病门诊患者接受营养咨询和烹饪协助后的营养变化
Pub Date : 2023-06-24 DOI: 10.14710/jgi.11.2.110-118
Rany Adelina, Awalia Nanda Arianto, Sabrina Julietta Arisanty, Rafika Aprillia, Wisnowan Hendy Saputra, Risa Mafaza, Khairuddin Khairuddin, Tapriadi Tapriadi, Rathi Paramastri
ABSTRACTBackground: Nutrition and diets are critical factors for T2DM patients to maintain health. Nutrition education are considered less effective because most patients have not implemented them. This research tries to develop program innovation by combining nutrition counseling and cooking assistance for T2DM outpatients. This study aimed to know the risk factors for T2DM  and determine the effectiveness of programmed nutrition education (NEP) on changes in nutrient intake in patients with T2DM. Methods: A total of 70 participants registered as T2DM outpatients at Kedung Kandang primary healthcare center in Malang city. Subjects were recruited using a 'quota sampling' technique. The design of this study is a quasi-experiment study using a comparison of the control (n=32)-treatment group (n=38). This research was conducted from September to November 2018. Fifty minutes of intensive individual counseling and cooking assistance were provided to T2DM patients and families. The data were analyzed using independent sample t-test, Wilcoxon Mann Whitney U-test, and logistic regression. The patients’ 4-d dietary records of 3 normal days and 1 holiday/weekend were assessed after 24 hours.Results: From this study it can be seen that intake of amino acid lysine was significantly higher in the  treatment group than the control group (p = 0.04). The intake of fiber, MUFA, and PUFA was greater in the intervention group, while sodium intake was lower in the intervention group. The risk factors of T2DM incidence were age (p = 0.036), education (p = 0.043), waist circumference (p = 0.015), and carbohydrate intake (p = 0.033). Conclusion: T2DM patients treated with individual nutrition counseling and cooking assistance gained a higher intake of fiber, amino acid lysine, and unsaturated fatty acids. The most influential risk factors of T2DM incidence are age, education, waist circumference, and carbohydrate intake. Keywords: nutrition counseling, cooking assistance, nutritional intake, T2DM.
摘要背景:营养和饮食是T2DM患者维持健康的关键因素。营养教育被认为效果较差,因为大多数患者没有实施营养教育。本研究尝试将2型糖尿病门诊患者的营养咨询与烹饪援助相结合,进行项目创新。本研究旨在了解T2DM的危险因素,并确定计划营养教育(NEP)对T2DM患者营养摄入变化的有效性。方法:在麻郎市Kedung Kandang初级卫生保健中心登记的T2DM门诊患者共70例。研究对象采用“配额抽样”技术招募。本研究设计为准实验研究,将对照组(n=32)与实验组(n=38)进行比较。该研究于2018年9月至11月进行。为2型糖尿病患者和家属提供了50分钟的密集个人咨询和烹饪协助。数据分析采用独立样本t检验、Wilcoxon Mann Whitney u检验和logistic回归。24小时后评估患者3个工作日和1个节假日/周末的4 d饮食记录。结果:从本研究中可以看出,治疗组的氨基酸赖氨酸摄入量明显高于对照组(p = 0.04)。干预组的纤维、MUFA和PUFA的摄入量更高,而钠的摄入量则更低。T2DM发病的危险因素为年龄(p = 0.036)、文化程度(p = 0.043)、腰围(p = 0.015)、碳水化合物摄入(p = 0.033)。结论:接受个人营养咨询和烹饪辅助治疗的2型糖尿病患者获得了更高的纤维、氨基酸赖氨酸和不饱和脂肪酸的摄入量。年龄、受教育程度、腰围和碳水化合物摄入量是影响2型糖尿病发病率的主要危险因素。关键词:营养咨询,烹饪辅助,营养摄入,2型糖尿病。
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引用次数: 0
COMPARISON BETWEEN METABOLIC PARAMETERS, FOOD INTAKE, AND GUT MICROBIOTA IN TYPE 2 DIABETES AND NON-DIABETIC INDONESIAN WOMEN 印度尼西亚2型糖尿病和非糖尿病妇女的代谢参数、食物摄入和肠道微生物群的比较
Pub Date : 2023-06-24 DOI: 10.14710/jgi.11.2.119-127
N. Rustanti, A. Murdiati, M. Juffrie, E. Rahayu
ABSTRACTBackground: Globally, the increasing incidence of type 2 diabetes mellitus (T2D) has resulted in an upsurge in research into this metabolic condition. Women, particularly in Indonesia, have a greater risk of T2D than males. The diversity of the gut microbiota (GM) in T2D is regulated by the number of carbs, protein, fat, and fiber consumed. Objectives: This study examined the comparison between metabolic parameters, food intake, and GM in T2D and non-diabetic Indonesian women.Materials and Methods: The cohort study included people who did not have T2D and those who did. On day 28 of observations, anthropometric, metabolic parameters, food intake, physical activity, and feces were collected. Feces were collected for pH, SCFA, and GM (L. plantarum, Bifidobacterium, and Prevotella) analysis. Results: There were significant differences between non-diabetic and diabetic women in age, Waist Hip Ratio (WHR), fasting blood sugar (FBS), and HbA1c. The two groups did not differ significantly in terms of their macronutrient intake (calories, carbs, protein, and fat), total water, and dietary fiber. Fecal pH and GM did not statistically differ between the control and T2D groups. Fasting blood sugar and HbA1c were positively associated with age, duration of T2D, WHR, and total water consumption, but slightly negatively associated with dietary fiber intake. Fasting blood sugar  was also slightly negatively associated with Prevotella, meanwhile HbA1c with Bifidobacterium. Carbohydrate intake were positively correlated with acetic, propionic, and butyric acid levels.Conclusion: Macronutrient intake, fecal pH, SCFA, and GM did not differ because GM in T2D increased bacause metformin consumption so that SCFA similar between two group. Keywords : food, gut microbiota, short-chain fatty acid,  diabetes, women 
摘要背景:在全球范围内,随着2型糖尿病(T2D)发病率的增加,对这一代谢疾病的研究激增。女性,特别是在印度尼西亚,患T2D的风险高于男性。T2D患者肠道微生物群(GM)的多样性受碳水化合物、蛋白质、脂肪和纤维摄入量的调节。目的:本研究考察了t2dm和非糖尿病印度尼西亚妇女的代谢参数、食物摄入和GM之间的比较。材料和方法:队列研究包括无T2D患者和有T2D患者。在观察的第28天,收集人体测量、代谢参数、食物摄入量、身体活动和粪便。收集粪便进行pH、SCFA和GM(植物乳杆菌、双歧杆菌和普雷沃氏菌)分析。结果:非糖尿病女性与糖尿病女性在年龄、腰臀比(WHR)、空腹血糖(FBS)、糖化血红蛋白(HbA1c)方面均有显著差异。两组在常量营养素摄入量(卡路里、碳水化合物、蛋白质和脂肪)、总水量和膳食纤维方面没有显著差异。粪便pH和GM在对照组和T2D组之间无统计学差异。空腹血糖和HbA1c与年龄、T2D病程、WHR和总饮水量呈正相关,与膳食纤维摄入量呈轻微负相关。空腹血糖与普雷沃氏菌呈轻微负相关,而HbA1c与双歧杆菌呈轻微负相关。碳水化合物摄入量与乙酸、丙酸和丁酸水平呈正相关。结论:大营养摄取量、粪便pH值、SCFA和GM没有差异,因为二甲双胍的摄入增加了T2D的GM,所以SCFA在两组之间相似。关键词:食物,肠道菌群,短链脂肪酸,糖尿病,女性
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引用次数: 1
Evaluation of the provision of enteral nutrition in critically ill patients receiving mechanical ventilation 危重病人接受机械通气肠内营养的评估
Pub Date : 2023-01-31 DOI: 10.21927/ijnd.2023.11(1).30-39
Meike Mayasari, Fella Farikhatul Mahmudah, Silviana Perwitasari, U. Rahayu
                                                            ABSTRACTBackground: Providing enteral nutrition to ICU patients is often challenging, leading to sufficient enteral nutrition that is hardly achieved. This condition is caused by gastrointestinal motility disorder and other complications that often happen during enteral nutrition provision. Therefore, it is important to understand the level of nutritional support and the challenges in the form of interruption during enteral nutrition to critically ill patients receiving mechanical ventilation to optimise the benefit of nutritional support for patients, including reducing the duration of hospitalisation and mortality.Objectives: This study aims to evaluate the provision of enteral nutrition and identify the cause of interruption for patients with mechanical ventilation in one of the tertiary hospitals in Yogyakarta, Indonesia who receive enteral nutrition.Methods: This is a cross-sectional study. The subject of the study is patients who fulfil the inclusion and exclusion criteria. Inclusion criteria include patients who were in ICU for ≥72 hours, receiving mechanical ventilation. While the exclusion criteria include patients with contraindications for enteral nutrition such as unstable haemodynamic, bowel obstruction, persistent severe ileus, gastrointestinal bleeding, nasogastric tube (NGT) placement is not possible, patients receiving oral nutrition with non-invasive ventilation, patients with feeding tube before admission, or patients from other ICU or HCU.Results: Patients needed, on average, 13 hours to receive initial enteral nutrition (SD ± 9.89 hours), with a period between 0 – 50 hours since admission to ICU. The mean time for patients to receive full feeding is 4 days ± 2.4 days. On the other hand, 16 out of 75 patients (21.2%) did not reach the targeted intake during admission. The cause of the interruption of enteral nutrition includes gastric residual volume (GRV), percutaneous dilatation tracheostomy (PDT) procedure, vomiting, bloating, surgery, CT scan, etc.Conclusion: Many causes of interruption and inadequate intake of enteral nutrition can be prevented. The absence of protocol agreed upon by the patient care team could be one of the influencing factors.KEYWORD:  enteral nutrition; enteral nutrition interruption; mechanical ventilation 
摘要背景:为ICU患者提供肠内营养往往具有挑战性,导致肠内营养难以实现。这种情况是由胃肠运动障碍和肠内营养提供过程中经常发生的其他并发症引起的。因此,了解接受机械通气的危重患者的营养支持水平和肠内营养中断形式的挑战,以优化患者的营养支持益处,包括减少住院时间和死亡率,是很重要的。目的:本研究旨在评估肠内营养的提供,并确定在印度尼西亚日惹的一家三级医院接受肠内营养的机械通气患者中断的原因。方法:这是一个横断面研究。研究对象为符合纳入和排除标准的患者。纳入标准为ICU≥72小时,接受机械通气的患者。排除标准包括有肠内营养禁忌症的患者,如血流动力学不稳定、肠梗阻、持续性严重肠梗阻、胃肠道出血、无法放置鼻胃管(NGT)的患者、在无创通气下接受口服营养的患者、入院前有喂食管的患者或来自其他ICU或HCU的患者。结果:患者接受初始肠内营养平均需要13小时(SD±9.89小时),时间为入ICU后0 ~ 50小时。患者获得全饲的平均时间为4天±2.4天。另一方面,75例患者中有16例(21.2%)在入院时未达到目标摄入量。肠内营养中断的原因包括胃残留量(GRV)、经皮气管扩张造口术(PDT)、呕吐、腹胀、手术、CT扫描等。结论:许多原因的肠内营养中断和摄入不足是可以预防的。患者护理团队没有达成一致的协议可能是影响因素之一。关键词:肠内营养;肠内营养中断;机械通风
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引用次数: 0
Predisposing, supporting and reinforcing factors of stunting risk: A case-control study 发育迟缓风险的诱发、支持和强化因素:一项病例对照研究
Pub Date : 2023-01-31 DOI: 10.21927/ijnd.2023.11(1).11-21
Rotua Sitorus, Dewi Sartika Munthe, Lidya Natalia Br Sinuhaji, Tetti Seriati Situmorang, Samsider Sitorus

ABSTRAK

Latar Belakang: Pemerintah Indonesia telah menetapkan stunting sebagai isu prioritas nasional dalam Rencana Pembangunan Jangka Menengah Nasional (RPJMN) dengan target penurunan stunting yang signifikan sebesar 14% pada tahun 2024.

Tujuan: Penelitian ini bertujuan untuk membahas prevalensi terkini dan mengungkap faktor risiko terbesar kasus stunting di kota Medan dengan metode kuantitatif dengan desain case-control. Kasus stunting tertinggi di Kota Medan terdapat di Puskesmas Kecamatan Medan Tembung yaitu 442 anak dari 6.603 anak balita.

Metode: Penelitian ini menggunakan desain kasus-kontrol. Data diperoleh dengan teknik purposive sampling. Data populasi adalah 442 ibu balita stunting yang terdiri dari 30 ibu sebagai kasus dan 30 ibu sebagai kontrol. Data dianalisis dengan analisis univariat, bivariat, dan multivariat.

Hasil: Hasil penelitian menunjukkan bahwa pengetahuan (p = 0,034), tindakan (p = 0,033), sikap (p = 0,029), dukungan kader (p = 0,027), pendapatan keluarga (p = 0,019), dan dukungan keluarga (p = 0,008). ) berpengaruh pada ibu yang berisiko melahirkan balita stunting. Dukungan keluarga yang buruk sebagai faktor dominan memiliki risiko 12,6 kali ibu melahirkan balita stunting.

Kesimpulan: Kajian ini menyarankan agar Dinas Kesehatan Kota Medan memperkuat koordinasi lintas sektoral antara pemerintah kecamatan, puskesmas, dan kelurahan secara bersama-sama dan berkomitmen untuk menurunkan angka kejadian stunting di Kota Medan.

 

KATA KUNCI: dukungan Keluarga; faktor risiko; Kota Medan; stunting 

 

 

ABSTRACT

Background: The Indonesian government has designated stunting as a national priority issue in the National Medium-Term Development Plan (RPJMN) with a target of a significant stunting reduction to be 14 % in 2024.

Objectives: This research aims to address the recent prevalence and to reveal the most risk factor of stunting cases in Medan city with a quantitative method with a case-control design. The highest cases of stunting in Medan city were found at the Public Health Center in Medan Tembung district, namely 442 children out of 6,603 children under five.

Methods: This study used a case-control design. Data were obtained by the purposive sampling technique. The population data was 442 mothers with stunting toddlers consisting of 30 mothers as cases and 30 as controls. Data were analyzed by univariate, bivariate, and multivariate analyses.

Results: The

抽象背景:印度尼西亚政府将这一打击定为国家中期发展计划(RPJMN)的国家优先事项,目标是到2024年将这一目标显著降低14%。目的:本研究的目的是研究目前的流行情况,并用定量方法控制控制设计,揭示棉兰市最危险的特技因素。在普斯马斯青少年中心,6603名5岁以下儿童中有442名儿童。方法:这项研究采用了案例控制设计。数据是通过采样技术获得的。人口统计是442名蹒跚学步的母亲的发育迟缓,由30名母亲组成,由30名母亲控制。数据通过单变量、双变量和多变量分析进行分析。结果:研究表明,知识(p = 034)、行动(p = 033)、态度(p = 0.029)、卡德支持(p = 0.027)、家庭收入(p = 0.019)和家庭支持(p = 0.008)。影响了有生育孩子危险的母亲。家庭支持不好,占主导地位的因素有12.6倍的母亲发育发育的风险。结论:这项研究建议棉兰市卫生服务部门加强联邦街道、puskesmas和透明度政府之间的跨部门协调,并承诺降低棉兰城市特技发生率。关键词:家庭支持;风险因素;城市地形;ABSTRACTBackground:印尼政府设计了一项国家发展计划(RPJMN)的国家优先问题,其目标有一个重要的延误减减到2024年的14%。目标研究:这一研究有助于说出潜在的预防措施,并揭示出在这个城市中使用量量的方法和防控设计的风险最大的因素。我们在Medan city发现了当地的公共卫生中心,namely 442个孩子在5岁的6 603个孩子中出生。这个研究用的是防控设计。数据是由采集器技术验证的。数据的人口是442名脚趾发育不良的母亲,其记录的是30位母亲,as cases and 30 as controls。数据是对单变量、双变量和多变量分析的分析。Results: Results表明,知识(p = 034)、行为(p = 033)、行为(p = 029)、catitudes (p = 0027)、家庭收入(p = 019)和家庭支持(p = 019)在冒着使儿童发育迟缓的风险时对母亲产生了影响。作为统治者,可怜的家庭支持机构拥有12.6倍高的母亲风险,让新生儿怀孕。结论:这项研究建议,野战市的健康服务人员必须加强我们地区行政、卫生中心和恶棍之间的交叉协调。关键词:家庭支持;风险因子;城市地形;发育迟缓
{"title":"Predisposing, supporting and reinforcing factors of stunting risk: A case-control study","authors":"Rotua Sitorus, Dewi Sartika Munthe, Lidya Natalia Br Sinuhaji, Tetti Seriati Situmorang, Samsider Sitorus","doi":"10.21927/ijnd.2023.11(1).11-21","DOIUrl":"https://doi.org/10.21927/ijnd.2023.11(1).11-21","url":null,"abstract":"<p align=\"center\"><strong>ABSTRAK </strong></p><p><strong><em>Latar Belakang</em></strong><em>: Pemerintah Indonesia telah menetapkan stunting sebagai isu prioritas nasional dalam Rencana Pembangunan Jangka Menengah Nasional (RPJMN) dengan target penurunan stunting yang signifikan sebesar 14% pada tahun 2024.</em></p><p><strong><em>Tujuan</em></strong><em>: Penelitian ini bertujuan untuk membahas prevalensi terkini dan mengungkap faktor risiko terbesar kasus stunting di kota Medan dengan metode kuantitatif dengan desain case-control. Kasus stunting tertinggi di Kota Medan terdapat di Puskesmas Kecamatan Medan Tembung yaitu 442 anak dari 6.603 anak balita.</em></p><p><strong><em>Metode:</em></strong><em> Penelitian ini menggunakan desain kasus-kontrol. Data diperoleh dengan teknik purposive sampling. Data populasi adalah 442 ibu balita stunting yang terdiri dari 30 ibu sebagai kasus dan 30 ibu sebagai kontrol. Data dianalisis dengan analisis univariat, bivariat, dan multivariat.</em></p><p><strong><em>Hasil:</em></strong><em> Hasil penelitian menunjukkan bahwa pengetahuan (p = 0,034), tindakan (p = 0,033), sikap (p = 0,029), dukungan kader (p = 0,027), pendapatan keluarga (p = 0,019), dan dukungan keluarga (p = 0,008). ) berpengaruh pada ibu yang berisiko melahirkan balita stunting. Dukungan keluarga yang buruk sebagai faktor dominan memiliki risiko 12,6 kali ibu melahirkan balita stunting.</em></p><p><strong><em>Kesimpulan:</em></strong><em> Kajian ini menyarankan agar Dinas Kesehatan Kota Medan memperkuat koordinasi lintas sektoral antara pemerintah kecamatan, puskesmas, dan kelurahan secara bersama-sama dan berkomitmen untuk menurunkan angka kejadian stunting di Kota Medan.</em></p><p><em> </em></p><p><strong>KATA KUNCI<em>: </em></strong><em>d</em><em>ukungan Keluarga; faktor risiko; <em>Kota Medan; s</em>tunting </em></p><p align=\"center\"><strong> </strong></p><p><strong> </strong></p><p align=\"center\"><strong>ABSTRACT</strong></p><p><strong><em>Background: </em></strong><em>The Indonesian government has designated stunting as a national priority issue in the National Medium-Term Development Plan (RPJMN) with a target of a significant stunting reduction to be 14 % in 2024.</em><em></em></p><p><strong><em>Objectives: </em></strong><em>This research aims to address the recent prevalence and to reveal the most risk factor of stunting cases in Medan city with a quantitative method with a case-control design. The highest cases of stunting in Medan city were found at the Public Health Center in Medan Tembung district, namely 442 children out of 6,603 children under five.</em></p><p><strong><em>Methods: </em>This study used a case-control design. </strong><em>Data were obtained by the purposive sampling technique. The population data was 442 mothers with stunting toddlers consisting of 30 mothers as cases and 30 as controls. Data were analyzed by univariate, bivariate, and multivariate analyses.</em></p><p><strong><em>Results: </em></strong><em>The ","PeriodicalId":32498,"journal":{"name":"Jurnal Gizi Indonesia The Indonesian Journal of Nutrition","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74689384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of macronutrient intake and body fat precentage with menstrual cycle 大量营养素摄入和体脂率与月经周期的关系
Pub Date : 2023-01-31 DOI: 10.21927/ijnd.2023.11(1).22-29
Nadya Khaira Nurdi, D. Desmawati, Nita Afriani

ABSTRAK 

Latar Belakang: Hasil Riset Kesehatan Dasar Tahun 2010 menyatakan bahwa terdapat sebanyak 13,7% wanita di Indonesia mengalami siklus menstruasi tidak teratur, 7,7% disebabkan oleh faktor pola hidup. Sumatera Barat merupakan provinsi tiga tertinggi gangguan siklus menstruasi di Indonesia, dengan prevalensi sebesar 19,1% (3).

Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan antara jumlah asupan makronutrien dan kadar lemak tubuh dengan siklus menstruasi pada mahasiswi Fakultas Kedokteran Universitas Andalas.

Metode: Penelitian ini merupakan penelitian observasional dengan desain penelitian cross sectional. Penelitian ini dilaksanakan di Fakultas Kedokteran Universitas Andalas pada bulan November 2021-September 2022, dengan jumlah sampel sebanyak 78 orang. Sampel diperoleh secara sistematis berdasarkan interval sampel. Pengumpulan data dilakukan secara langsung dengan cara pemeriksaan fisik dan pengisian kuesioner. Analisis bivariat dilakukan dengan uji t-independen dan analisis multivariat dilakukan dengan regresi logistik.

Hasil: Hasil penelitian menyatakan bahwa 42,3% mahasiswi memiliki siklus menstruasi tidak normal, rerata jumlah asupan makronutrien (kalori total, karbohidrat, lemak, protein) dan kadar lemak tubuh mahasiswi adalah 2725,40±269,90 kkal, 378,86±40,70 gram, 90,58±14,40 gram, 98,54±11,36 gram, dan 36,19±7,02%. Uji T-independen menunjukkan bahwa terdapat hubungan yang bermakna antara jumlah asupan makronutrien (kalori total, karbohidrat, lemak, protein) dan kadar lemak tubuh dengan siklus menstruasi (p=0,000, 0,016, 0,005, 0,028, 0,000). Uji regresi logistik menunjukkan bahwa kadar lemak tubuh merupakan faktor yang paling dominan berhubungan dengan siklus menstruasi (p=0,000).

Kesimpulan: Adanya hubungan yang bermakna antara jumlah asupan makonutrien dan kadar lemak tubuh dengan siklus mentruasi. Serta, kadar lemak tubuh merupakan faktor yang paling dominan berhubungan dengan siklus menstruasi.

 

KATA KUNCI: asupan makronutrien; kadar lemak tubuh; siklus menstruasi

 

ABSTRACT

Background: Indonesian Basic Health Research 2010 state that 13.7% of women in Indonesia with irregular menstrual cycles, 7,7% caused by lifestyle factors. West Sumatra is the third highest province of irregular menstruation prevalence in Indonesia, which is 19.1% (3).

Objectives: The purpose of this research is to determine the relationship between macronutrient intake and body fat percentage with the menstrual cycle in femal

摘要背景:2010年基础卫生研究显示,印尼有13.7%的女性月经周期不规则,这是由生活方式因素造成的7.7%。西苏门答腊是印度尼西亚月经周期最严重的第三个省份,患病率为19.1%(3)。方法:本研究为交叉对角线研究设计的观察研究。该研究于2021年11月至2022年9月在安达拉斯大学医学院进行,样本人数为78人。通过样本间隔系统获得样本。数据收集是通过物理检查和问卷提交进行的。双变量分析是通过独立测试进行的,而多变量分析是通过物流回归进行的。结果:研究结果指出,42,3%大学生人数有月经周期不正常,平均总makronutrien(卡路里摄入碳水化合物,脂肪,蛋白质),女生的身体脂肪含量是2725.40±269.90 kkal, 378.86±40,70克,90.58±14,40克,98.54±11.36克,36,19±7,02%。独立的t - dict测试表明,马科utrien摄入量(总热量、碳水化合物、脂肪、蛋白质)和经水循环的身体脂肪水平(p= 0000,016, 005, 0.028, 0000)之间存在着有意义的联系。物流回归测试表明,身体脂肪水平是与月经周期相关的主要因素。结论:makonutrien摄入量与身体脂肪水平的稳定周期之间存在显著的联系。此外,身体脂肪水平是与月经周期最重要的因素。关键词:makronutrien入口;身体脂肪水平;摘要背景月经周期:印尼基础健康研究2010州有13.7%经期周期妇女,生活方式因素为7.7%的原因。西苏门答腊是印度尼西亚最严重的经期先验省,其目标是19.1%(3)。方法:这项研究是跨部门研究的观察研究。本研究是2011年11月21日至2022年9月22日安达拉斯大学医学院采用的,样本有78个回答。样本是基于intervals样本的系统。数据是由物理研究和提问收集的。两变量分析用于独立样本t测试和多变量分析用于回归。Results: The Results of this research stated that 42,3% of respondents有irregular menstruation macronutrient进气(calories之卑鄙,carbohydrate,胖,蛋白质)和身体胖percentage of respondents是2725.40±269.90 kcal, 378.86±40,70克,90.58±14,40克,98.54±11.36克,和36,19±7,02%。《独立样本t测试》在macronutrient入口(calories, carbohydrate, fat,蛋白质)和月经周期的身体发色(p= 016, 0005, 0.028和000)之间有意义的关系。生理反射测试表明,这个身体是月经周期的主动脉特征。这个研究的结论是macronutrient入口和身体脂肪周期的重要关系。同时,身体脂肪作为统治者的经期周期因素。身体脂肪更新;macronutrients进气;经期周期
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引用次数: 0
The effect of omega-3 fatty acids and vitamin E supplementation on lipid profiles and inflammatory markers in hemodialysis patients: A systematic review of current literature 补充omega-3脂肪酸和维生素E对血液透析患者血脂和炎症标志物的影响:对当前文献的系统回顾
Pub Date : 2023-01-31 DOI: 10.21927/ijnd.2023.11(1).1-10
Ahila Meliana, Ameilia Anastasya Rahma Afizah, Nurina Hasanatuludhhiyah

ABSTRAK

Latar Belakang: Kebutuhan terapi hemodialisis (HD) masih terus berkembang. Di Indonesia, HD mewakili 82% dari pelayanan cuci darah di Puskesmas Indonesia. Namun, HD menyebabkan peningkatan penanda inflamasi serta perubahan profil lipid. Kombinasi vitamin E dan asam lemak omega-3 dapat membantu mengurangi indikator inflamasi dan meningkatkan profil lipid.

Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh co-suplementasi vitamin E dan omega-3 terhadap profil lipid dan indikator inflamasi.

Metode: Penelitian ini dilakukan di PubMed dan Google Scholar untuk mencari artikel-artikel secara sistematis, Kriteria inklusi yang digunakan adalah artikel bahasa Inggris dengan uji coba terkontrol acak (RCT) dan uji coba terkontrol (CT) yang menyelidiki efek vitamin E dan omega-3 pada profil lipid dan penanda inflamasi pasien hemodialisis. Semua artikel harus diterbitkan antara September 2013 - September 2022. AM dan AA melakukan seluruh proses penelitian sebagai reviewer dan seluruh ketidaksetujuan diselesaikan bersama NH sebagai penulis ketiga.

Hasil: 1020 studi diidentifikasi dari database dan 12 artikel terpilih berdasarkan kriteria inklusi. Asam lemak omega-3 meningkatkan profil lipid, seperti kolesterol, LDL, HDL, dan trigliserida. Namun, studi ini hanya menemukan satu penelitian tentang efek vitamin E pada profil lipid. Asam lemak Omega-3 dan suplementasi vitamin E tidak memiliki efek signifikan pada penanda inflamasi, tetapi dampak suplementasi vitamin E pada tingkat IL-6 telah dilaporkan.

Kesimpulan: Co-suplementasi Omega-3 dan vitamin E berpengaruh pada penurunan level indikator inflamasi dan profil lipid pasien hemodialisis. Kami merekomendasikan bahwa studi berikutnya harus berfokus pada penelitian uji klinis mengenai pengaruh suplementasi kombinasi ini terhadap indikator inflamasi dan profil lipid pasien hemodialisis.

 

KATA KUNCI: hemodialisis; indikator inflamasi; omega-3; profil lipid; vitamin E

 

ABSTRACT

Background: Hemodialysis therapy (HD) demands is still growing. In Indonesia, HD represents 82% of dialysis services in Indonesian health centers. However, HD causes an increase in inflammatory markers as well as lipid profile changes. The combination of vitamin E and omega-3 fatty acids can assist to decrease inflammatory indicators and enhance lipid profiles.

Objectives: This study aims to investigate the effect of co-supplementation of vitami

摘要背景:血液透析治疗(HD)的需求仍在增长。在印度尼西亚,HD代表了印尼Puskesmas中82%的透析服务。然而,HD导致炎症标记增加和脂质剖面图改变。维生素E和omega-3脂肪酸的结合可以帮助减少炎症指标和增强脂质剖面。目的:本研究旨在确定维生素E和omega-3对脂透镜和炎症指标的共同作用。方法:这项研究是在PubMed和谷歌Scholar系统地搜索文章时进行的,使用的包容标准是一篇使用的英语文章,使用的是随机对照试验(RCT)和控制测试(CT),研究维生素E和omega-3脂肪酸对脂资料的影响,以及血液透析患者炎症标记。所有文章必须在2013年9月至2022年9月之间发表。作为第三位作家,AM和AA把整个研究过程作为评论者和整个反对意见结合起来。结果:1020项研究是根据数据库和12项根据纳入标准确定的研究。omega-3脂肪酸增加了脂质轮廓,如胆固醇、LDL、HDL和甘油三酯。然而,这项研究只发现了一项关于维生素E对脂透镜影响的研究。维生素E -3脂肪酸和补充素对炎症标记没有明显影响,但维生素E补充作用已报告。结论:欧米伽-3和维生素E的共集作用于血液透析患者的炎症指标和脂质轮廓降低。我们建议,下一项研究应该集中研究这种结合疗法对血液透析患者的炎症指标和脂质轮廓的影响。关键词:血液透析;炎症指标;omega - 3;脂肪的资料;维生素E抽象背景:血液透析治疗仍然在增长。在印度尼西亚,HD代表的是印尼健康中心82%的透析服务。However, HD原因随着lipid配置变化而增加。维生素E和-3脂肪酸的结合可能会帮助去除炎症酸和脂肪剖析。客观研究:这一研究旨在研究淀粉脂和炎症性状上维生素E和-3脂肪酸共同作用的研究结果。方法:这项研究是基于公共和谷歌学者搜索系统的结果。过去的界标包括英国《愤怒控制试验》和《控制试验》(CT)调查维生素E和omega-3脂肪酸淀粉淀粉斑块的效果。所有的文章必须在2013年9月到2022年9月之间发表。美国审查和所有的挑战都以第三次author结束。结果:1020个研究数据表明身份。在沃德之后,这个研究包括12篇关于critcision的论文。-3脂肪酸酸盐粉,像巧克力醇,LDL, HDL和triglyceride。虽然我们只发现了一种关于配料中维生素E效果的研究。Furthermore, -3脂肪酸和维生素E补充对炎症马尔克斯没有重要影响,但报告报告了维生素E补充的影响。结清:血液透析病人苯胺-3和维生素E脱毛酶的共补充剂和脂肪酶水平。我们所要求的未来研究应该集中在临床试验中,以调查血液透析病人软膏和炎症标记的效果。KEYWORD: hemodialysis;了炎性标记;脂肪》;omega-3,维生素E
{"title":"The effect of omega-3 fatty acids and vitamin E supplementation on lipid profiles and inflammatory markers in hemodialysis patients: A systematic review of current literature","authors":"Ahila Meliana, Ameilia Anastasya Rahma Afizah, Nurina Hasanatuludhhiyah","doi":"10.21927/ijnd.2023.11(1).1-10","DOIUrl":"https://doi.org/10.21927/ijnd.2023.11(1).1-10","url":null,"abstract":"<p align=\"center\"><strong>ABSTRAK </strong></p><p><strong><em>Latar Belakang: </em></strong><em>Kebutuhan terapi hemodialisis (HD) masih terus berkembang. Di Indonesia, HD mewakili 82% dari pelayanan cuci darah di Puskesmas Indonesia.</em><strong><em> </em></strong><em>Namun, HD menyebabkan peningkatan penanda inflamasi serta perubahan profil lipid. Kombinasi vitamin E dan asam lemak omega-3 dapat membantu mengurangi indikator inflamasi dan meningkatkan profil lipid.</em></p><p><strong><em>Tujuan: </em></strong><em>Penelitian ini bertujuan untuk mengetahui pengaruh co-suplementasi vitamin E dan omega-3 terhadap profil lipid dan indikator inflamasi.</em></p><p><strong><em>Metode: </em></strong><em>Penelitian ini dilakukan di PubMed dan Google Scholar untuk mencari artikel-artikel secara sistematis, Kriteria inklusi yang digunakan adalah artikel bahasa Inggris dengan uji coba terkontrol acak (RCT) dan uji coba terkontrol (CT) yang menyelidiki efek vitamin E dan omega-3 pada profil lipid dan penanda inflamasi pasien hemodialisis. Semua artikel harus diterbitkan antara September 2013 - September 2022.</em> <em>AM dan AA melakukan seluruh proses penelitian sebagai reviewer dan seluruh ketidaksetujuan diselesaikan bersama NH sebagai penulis ketiga.</em><strong><em></em></strong></p><p><strong><em>Hasil: </em></strong><em>1020 studi diidentifikasi dari database dan 12 artikel terpilih berdasarkan kriteria inklusi. Asam lemak omega-3 meningkatkan profil lipid, seperti kolesterol, LDL, HDL, dan trigliserida. Namun, studi ini hanya menemukan satu penelitian tentang efek vitamin E pada profil lipid. Asam lemak Omega-3 dan suplementasi vitamin E tidak memiliki efek signifikan pada penanda inflamasi, tetapi dampak suplementasi vitamin E pada tingkat IL-6 telah dilaporkan.</em><strong><em></em></strong></p><p><strong><em>Kesimpulan: </em></strong><em>Co-suplementasi</em><strong><em> </em></strong><em>Omega-3 dan vitamin E berpengaruh pada penurunan level indikator inflamasi dan profil lipid pasien hemodialisis. Kami merekomendasikan bahwa studi berikutnya harus berfokus pada penelitian uji klinis mengenai pengaruh suplementasi kombinasi ini terhadap indikator inflamasi dan profil lipid pasien hemodialisis.</em></p><p><em> </em></p><p><strong>KATA KUNCI</strong><strong><em>: </em></strong><em>hemodialisis; indikator inflamasi; omega-3; profil lipid; vitamin E</em></p><p><em> </em></p><p align=\"center\"><strong>ABSTRACT</strong></p><p><strong><em>Background: </em></strong><em>Hemodialysis therapy (HD) demands is still growing. In Indonesia, HD represents 82% of dialysis services in Indonesian health centers.</em><em> However, HD causes an increase in inflammatory markers as well as lipid profile changes. The combination of vitamin E and omega-3 fatty acids can assist to decrease inflammatory indicators and enhance lipid profiles.</em><em></em></p><p><strong><em>Objectives: </em></strong><em>This study aims to investigate the effect of co-supplementation of vitami","PeriodicalId":32498,"journal":{"name":"Jurnal Gizi Indonesia The Indonesian Journal of Nutrition","volume":"100 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76242191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Jurnal Gizi Indonesia The Indonesian Journal of Nutrition
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