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Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference最新文献

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A biomechanical study of 150/spl deg/ vs. 135/spl deg/ hip screws in femoral neck fractures 股骨颈骨折150/spl°/与135/spl°/髋螺钉的生物力学研究
Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514427
G. Lynn, D. P. Mukherjee, R. N. Kruse, K. Sadasivan*, J. Albright
Femoral neck fractures have been difficult to treat with nonunion and avascular necrosis reported in 10% to 40% of cases. The hypothesis tested here was to determine whether a femoral neck fracture fixed with a 150/spl deg/ screw is more stable than that fixed with a 135/spl deg/ screw. The objectives were to measure axial stiffness, torsional stiffness, and failure strength of femoral neck fractures (Pauwels III). Also, CT derived bone mineral density (BMD in units of K/sub 2/KPO/sub 4/ mg/cc equivalent) was measured. The following results were obtained: 1) The 150/spl deg/ hip screw demonstrated greater axial stiffness, as well as a preferred mode of failure (impaction at the fracture site). This is less likely to lead to nonunion or avascular necrosis than is the shearing action at the fracture site with the 135/spl deg/ hip screw. 2) The 135/spl deg/ hip screw demonstrated greater resistance to rotation. 3) CT derived BMD did not correlate with either axial or torsional stiffness of intact or fixed bones.
股骨颈骨折难以治疗,有10% - 40%的病例伴有骨不连和无血管坏死。本研究检验的假设是确定150/spl°螺钉固定股骨颈骨折是否比135/spl°螺钉固定股骨颈骨折更稳定。目的是测量股骨颈骨折的轴向刚度、扭转刚度和破坏强度(Pauwels III)。此外,还测量了CT衍生的骨矿物质密度(BMD,单位为K/sub 2/KPO/sub 4/ mg/cc当量)。得到以下结果:1)150/spl度/髋关节螺钉具有更大的轴向刚度,以及首选的失效模式(在骨折部位撞击)。与135/spl度/髋螺钉在骨折部位的剪切作用相比,这更不容易导致骨不连或缺血性坏死。2) 135/spl度/髋关节螺钉表现出更大的旋转阻力。3) CT得出的骨密度与完整或固定骨的轴向或扭转刚度无关。
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引用次数: 0
Multiresolution characterization of interictal epileptic spikes based on a wavelet transformation 基于小波变换的癫痫发作间期峰多分辨率表征
Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514476
Armando Barreto, N. Chin, J. Andrian, J. Riley
A wavelet transformation is applied to electrocorticogram (ECoG) records from epileptic patients. The temporal sharpness associated with interictal spikes at different resolutions is observed and two ways for representing the multiresolution sharpness of the spikes are proposed.
将小波变换应用于癫痫病人的脑皮质电图。观察了不同分辨率下与间隔尖峰相关的时间清晰度,并提出了两种表示尖峰多分辨率清晰度的方法。
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引用次数: 9
Location of the instantaneous center of rotation for shoulder motion 肩膀运动的瞬时旋转中心的位置
Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514490
A. Kumar, C. Jobe, S. Saha
Information regarding the instantaneous center of rotation for shoulder motion is important for the design of continuous passive motion (CPM) machines for the shoulders. In this study, we attempted to determine the locations of the instantaneous center of rotation for shoulder motion of the arm. Fourteen healthy adult subjects (age 18 to 30 years) participated in this study, five were females and the rest were males, The instantaneous center of rotation was computed for two different shoulder motions: (1) abduction motion in the sagittal plane and, (2) abduction motion in the coronal plane. The motion of the arm was monitored by a magnetic device (Polhemus). Our results showed that the location of the instantaneous center was much more proximal than the glenohumoral joint. It was located between 11 and 16 cm from the C/sub 7/ vertebra for the abduction in the coronal plane and this distance varied from 9 to 13 cm for the motion in sagittal plane.
关于肩部运动的瞬时旋转中心的信息对于肩部连续被动运动(CPM)机器的设计是重要的。在这项研究中,我们试图确定手臂肩部运动的瞬时旋转中心的位置。本研究选取了14名年龄在18 ~ 30岁的健康成人受试者,其中女性5名,男性5名。计算了两种不同肩部运动的瞬时旋转中心:(1)矢状面外展运动和(2)冠状面外展运动。手臂的运动由一个磁性装置(Polhemus)监测。我们的结果表明,瞬时中心的位置远比盂-体液关节近端。在冠状面外展时位于距C/下7/椎体11 - 16cm之间,在矢状面运动时位于9 - 13cm之间。
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引用次数: 4
Myoglobin facilitated oxygen diffusion in the heart: a mathematical assessment 肌红蛋白促进氧气在心脏的扩散:一个数学评估
Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514425
J. Gardner, R. W. Schubert
Previous theoretical assessments of myoglobin facilitation have failed to validate modeling results with a comparison to experimental data. In this study, myoglobin reaction kinetics is added to a proven cardiac tissue model in an effort to determine the extent of myoglobin facilitation. The mathematical model is compared to experimental pO/sub 2/ measurements taken from an isolated perfused cat heart preparation. The model is based upon the Krogh cylinder. In the tissue region there is axial diffusion, zero-order oxygen consumption, and myoglobin kinetics. Oxygen flux leaving the capillary is represented by a concentration difference times a mass transport coefficient, meaning that the tissue is considered "well mixed" radially. The tissue model is called the Radially-Averaged-Axially-Distributed (RAAD) model. Formulation of the mathematical problem describing the RAAD model yields a stiff, fourth-order, nonlinear, ordinary differential equation, boundary value problem. The equation set was solved numerically using a finite difference routine on a mainframe computer. The amount of diffusion facilitation by myoglobin was estimated by observing the inlet arteriolar pO/sub 2/ for the model with and without myoglobin. The computer simulations show that myoglobin does facilitate diffusion, but only to a small extent. The change in arteriolar pO/sub 2/ was less than 1% (0.76%). The facilitation is limited due to the low concentration and low diffusability of myoglobin in tissue. This suggests that facilitation of oxygen transport is not myoglobin's main physiological function.
先前对肌红蛋白促进的理论评估未能通过与实验数据的比较来验证模型结果。在这项研究中,肌红蛋白反应动力学被添加到一个已证实的心脏组织模型中,以确定肌红蛋白促进的程度。将数学模型与从离体灌注猫心脏制备中获得的实验pO/sub 2/测量值进行了比较。这个模型是以克拉夫圆柱为基础的。在组织区域有轴向扩散、零级氧消耗和肌红蛋白动力学。离开毛细管的氧通量由浓度差乘以质量传递系数表示,这意味着组织被认为是径向“充分混合”的。该组织模型称为径向平均轴向分布(RAAD)模型。描述RAAD模型的数学问题的公式产生一个刚性的,四阶的,非线性的,常微分方程,边值问题。在大型计算机上用有限差分程序对方程组进行了数值求解。通过观察有肌红蛋白和无肌红蛋白模型的入口小动脉pO/sub 2/来估计肌红蛋白促进扩散的量。计算机模拟表明肌红蛋白确实促进了扩散,但只是在很小的程度上。小动脉pO/sub 2/变化小于1%(0.76%)。由于组织中肌红蛋白的低浓度和低扩散性,促进作用受到限制。这表明促进氧运输并不是肌红蛋白的主要生理功能。
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引用次数: 0
Titanium Trace Metal Analysis of Tissue Overlaying Cervical Spine Plates in Dogs 犬颈椎板复盖组织的微量金属钛分析
Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514419
M. Martinez, R. Anderson, K. Bundy, D. Dinh
The goal of this study was to determine concentration distributions of titanium released from Ti-bA1-4V cervical spine plates i n canines and to relate this to observable implant surface damage. This research is part of an ongoing project to determine if there is a correlation between titanium release and plate strain and screw-plate interface motion in a canine cervical spine model. Two posterior cervical spine plates were implanted in four canines at the C4-C5 level. The overlaying tissue covering each implant was examined for trace levels of titanium using Inductively Coupled Plasma (ICP) Atomic Emission Spectroscopy. The highest titanium levels (>lo0 ppm dry wt.) were found in 1:issue samples closest to the screw- plate interfaces. Most of the surface damage observed was also found at these locations. Titanium was also found to have diffused into the tissue surrounding these locations.
本研究的目的是确定钛- ba1 - 4v颈椎板在犬体内释放的钛的浓度分布,并将其与可观察到的种植体表面损伤联系起来。这项研究是一个正在进行的项目的一部分,该项目旨在确定在犬颈椎模型中钛释放与钢板应变和螺钉-钢板界面运动之间是否存在相关性。在4只犬C4-C5水平植入2块颈椎后板。使用电感耦合等离子体(ICP)原子发射光谱检测覆盖每个植入物的覆盖组织的痕量钛水平。最高的钛含量(> 100ppm干重量)被发现在1:发行样品最接近螺丝板界面。观察到的大部分表面损伤也发生在这些位置。钛也被发现扩散到这些部位周围的组织中。
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引用次数: 0
Laserectomy of the human nucleus pulposus and intradiscal pressure measurements: an in vitro and in vivo study 人髓核激光切除术和椎间盘内压力测量:一项体外和体内研究
Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514494
H. Ranu
A new treatment technique has been developed to relieve the herniated disc symptoms. An Nd:YAG laser is used to vaporize a small volume of the nucleus pulposus and thus regressing the spinal disc. In vitro and in vivo intradiscal pressures are measured before, during and after laserectomy. The results show a significant reduction in intradiscal pressures after laserectomy, as a small volume of the nucleus pulposus is ablated.
一种新的治疗技术已经被开发出来以减轻椎间盘突出的症状。Nd:YAG激光用于汽化一小部分髓核,从而使椎间盘复位。在激光切除术之前、期间和之后测量离体和体内椎间盘内压力。结果显示激光切除术后椎间盘内压力显著降低,因为一小部分髓核被切除。
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引用次数: 2
Internal fixation of transverse acetabular fractures 髋臼横向骨折内固定
Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514430
S. Atchison, D. P. Mukherjee, R. N. Kruse, R. Mayeux, J. Albright
It has been shown that fixation of transverse acetabular fractures with a posterior plate and either an anterior column plate or screw provides adequate stability (see T. Sawaguchi et al., Acta Orthop. Scand., vol. 55, p. 601-5, 1984). The hypothesis tested in the current study is that simple transverse acetabular fractures can be fixed by posterior plating alone without the need for anterior column plating or screw fixation. If so, this would reduce operative time and eliminate the difficult task of anterior screw placement or dissection for anterior plating. So the objective of this study was to compare the stability of transverse acetabular fractures fixed with posterior plating alone versus posterior plating and anterior column screw fixation, at both zero and 90/spl deg/ of hip flexion. The authors conclude that: 1. The simple transverse acetabular fractures are "stable" when loaded at 0/spl deg/ of hip flexion and "unstable" when loaded at 90/spl deg/ of hip flexion. 2. There was a statistically significant difference in the axial stiffness and the posterior displacement at the fracture site when comparing no fixation versus fixation only at 90/spl deg/ hip flexion. But there was no significant difference when comparing posterior plating alone versus posterior plate and anterior column screw fixation at both 0/spl deg/ and 90/spl deg/ of hip flexion.
已有研究表明,用后路钢板和前柱钢板或螺钉固定髋臼横向骨折可提供足够的稳定性(见T. Sawaguchi等人,Acta Orthop。Scand。,第55卷,第601-5页,1984年)。本研究检验的假设是单纯的髋臼横向骨折可以单独通过后路钢板固定,而不需要前柱钢板或螺钉固定。如果是这样,这将减少手术时间,并消除前路螺钉放置或前路钢板剥离的困难任务。因此,本研究的目的是比较髋臼横向骨折在髋屈曲0度和90度时,单纯后路钢板固定与后路钢板+前柱螺钉固定的稳定性。作者得出结论:1。单纯髋臼横向骨折在髋屈曲0/spl度时为“稳定”,在髋屈曲90/spl度时为“不稳定”。2. 在90°/spl度/髋关节屈曲时,不固定与仅固定相比,骨折部位的轴向刚度和后路位移有统计学意义上的差异。但在髋关节屈曲0/spl度和90/spl度时,单独后路钢板与后路钢板+前柱螺钉固定比较无显著差异。
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引用次数: 2
Compliance of small-diameter vascular grafts as a determinant of patency 小直径血管移植物的顺应性是通畅的决定因素
Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514422
S.W. Mizelle, B. Gupta, V. Kasyanov
The success of small diameter vascular grafts in determining long term patency is highly limited due to the lack of compliance associated with the structures currently produced. The mismatch in compliance between the graft and the host artery has been noted as the primary cause for graft failure. Currently, there are many methods used to measure compliance, however there still exists a great deal of ambiguity in the measurements obtained by these methods. It is essential that the currently available measurement techniques be reviewed so that a simple standardized method for compliance measurement may be identified and used. The availability of such a method would lead to a significant reduction in the amount of inconsistency currently encountered by researchers when comparing compliance values.
由于目前生产的结构缺乏顺应性,小直径血管移植物在确定长期通畅方面的成功受到高度限制。移植物与宿主动脉之间的顺应性不匹配被认为是移植物失败的主要原因。目前,测量顺应性的方法很多,但这些方法得到的测量结果存在很大的模糊性。必须审查目前可用的测量技术,以便确定和使用一种简单的标准化的依从性测量方法。这种方法的可用性将大大减少目前研究人员在比较遵从性值时遇到的不一致的数量。
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引用次数: 3
Characterization of photoplethysmographic blood volume pulse waveforms for exercise evaluation 用于运动评估的光容积脉搏图血容量脉冲波形特征
Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514483
A. Barreto, M. Heimer, M. Garcia
The changes in the blood volume pulse (BVP) of exercising subjects are monitored and analyzed using three different approaches: averaged histogram, average periodogram and average beat amplitude and area. The results for all of these methods of analysis are shown.
采用平均直方图、平均周期图和平均搏动幅度和面积三种方法对运动对象血容量脉冲(BVP)的变化进行监测和分析。最后给出了所有这些分析方法的结果。
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引用次数: 11
Preliminary evaluation of titanium-coated PEEK implants 钛包覆PEEK植入物的初步评价
Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514436
A. M. Rust-Dawicki, S. Cook
A series of 40 titanium-coated and uncoated polyetheretherketone (PEEK) cylindrical implants were placed in unicortical sites in femurs of 4 mongrel dogs. The implants were evaluated mechanically and histologically at periods of 4 and 8 weeks. Interface attachment strength was calculated for each specimen, as well as measurements of bone contact, porosity, bone ingrowth, inflammatory response and mode of failure. Statistical analysis revealed the uncoated implants had significantly higher shear strength values at 4 weeks, but no significant difference from the coated implants at 8 weeks. There was no significant increase in bone contact between 4 and 8 weeks for either the coated or uncoated specimens. At both 4 and 8 weeks, the coated specimens had significantly higher percentages of bone contact.
将40个钛涂层和未涂层聚醚醚酮(PEEK)圆柱形植入物放置在4只杂种狗股骨的单皮质部位。在4周和8周期间对植入物进行机械和组织学评估。计算每个试样的界面附着强度,以及骨接触、孔隙度、骨向内生长、炎症反应和失效模式的测量。统计分析显示,未包覆种植体在第4周的抗剪强度值显著高于包覆种植体,但与包覆种植体在第8周的抗剪强度值无显著差异。在4到8周期间,无论是涂覆的还是未涂覆的标本,骨接触都没有显著增加。在第4周和第8周,包被标本的骨接触率显著提高。
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引用次数: 4
期刊
Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference
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