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Beyond physical exhaustion: Understanding overtraining syndrome through the lens of molecular mechanisms and clinical manifestation 超越体力衰竭:从分子机制和临床表现的角度理解过度训练综合征
IF 2.3 Q2 SPORT SCIENCES Pub Date : 2025-01-29 DOI: 10.1016/j.smhs.2025.01.006
Ondrej Fiala, Michaela Hanzlova, Lenka Borska, Zdenek Fiala, Drahomira Holmannova

Background

Overtraining Syndrome (OTS) is a condition resulting from excessive physical activity without adequate recovery, predominantly affecting elite athletes and military personnel. While overreaching can be a temporary state, non-functional overreaching may progress to chronic OTS. This review explores various hypotheses regarding the pathogenesis of OTS, including glycogen depletion, dysregulated cytokine response, oxidative stress, and alterations in the autonomic nervous system function. It also highlights the systemic impact of OTS on multiple organ systems, immune function, and overall health, linking the condition to chronic inflammation and an increased disease susceptibility. Additionally, it addresses the role of the gut microbiome in health modulation through physical activity.

Methods

This narrative review was conducted through a structured search of peer-reviewed journal articles in databases such as PubMed, Web of Science, and Google Scholar, focusing on studies involving human participants and published in English.

Results

OTS has systemic effects on multiple organ systems, immune function, and overall health, leading to chronic inflammation and increased disease susceptibility. Athletes with OTS exhibit higher morbidity rates, influenced by factors such as sleep deprivation and stress. The review also emphasizes the role of the gut microbiome as a significant modulator of health through physical activity.

Conclusion

Balanced training and recovery are crucial for preventing OTS and maintaining optimal health and quality of life in physically active individuals. Understanding the complex pathophysiology of OTS is essential for developing effective prevention and treatment strategies.
过度训练综合症(OTS)是一种由于过度体育活动而没有充分恢复而导致的疾病,主要影响精英运动员和军事人员。虽然过度伸展可能是一种暂时状态,但非功能性过度伸展可能会发展为慢性OTS。本文综述了关于OTS发病机制的各种假说,包括糖原耗竭、细胞因子反应失调、氧化应激和自主神经系统功能改变。它还强调了OTS对多器官系统、免疫功能和整体健康的全身性影响,将这种疾病与慢性炎症和疾病易感性增加联系起来。此外,它还通过身体活动解决了肠道微生物组在健康调节中的作用。方法:本文通过对PubMed、Web of Science和b谷歌Scholar等数据库中同行评议的期刊文章进行结构化搜索,重点关注涉及人类参与者并以英文发表的研究。结果sots对多器官系统、免疫功能和整体健康具有全身性影响,导致慢性炎症和疾病易感性增加。由于睡眠不足和压力等因素的影响,OTS运动员的发病率较高。该综述还强调了肠道微生物组通过身体活动作为健康的重要调节剂的作用。结论平衡的训练和恢复对预防OTS和维持最佳健康和生活质量至关重要。了解OTS复杂的病理生理机制对于制定有效的预防和治疗策略至关重要。
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引用次数: 0
Importance, unique aspects and guidelines, and building blocks of early childhood physical activity from a socioecological perspective 从社会生态学的角度来看,幼儿体育活动的重要性、独特方面和指导方针以及组成部分
IF 2.3 Q2 SPORT SCIENCES Pub Date : 2025-01-23 DOI: 10.1016/j.smhs.2025.01.004
Karin Allor Pfeiffer , Kimberly A. Clevenger
Although the benefits of physical activity are established across all age groups, researchers have recently noted that there is uncertainty as to which correlates and determinants of physical activity contribute to well-informed interventions and policies, particularly for the time frame of early childhood. The following narrative review highlights salient factors related to physical activity during early childhood, particularly in the United States, with respect to a socioecological framework. Discussion of factors at the individual (demographic, genetic), interpersonal (family support and perceptions of competence), organizational (e.g., preschool attended, preschool quality, teacher characteristics), community (availability, use, and perceptions of play spaces), and policy levels is included. While researchers often work within a public health framework that focuses on moderate-to-vigorous physical activity, or total (light-to-vigorous) physical activity, this may not fully align with how young children move. The importance of structured and unstructured play, risky play, and nature-based play are highlighted. Implications for basic and applied scientists, clinicians, and practitioners are addressed. Suggestions for future work include consideration of the context of physical activity, associations with other health behaviors, and further examination of the interpersonal and community level factors.
虽然身体活动的好处在所有年龄组都得到了证实,但研究人员最近指出,身体活动的哪些相关因素和决定因素有助于制定明智的干预措施和政策,尤其是在幼儿时期,这一点尚不确定。下面的叙述性回顾强调了与儿童早期身体活动有关的突出因素,特别是在美国,就社会生态框架而言。包括对个人(人口统计学、遗传)、人际(家庭支持和对能力的看法)、组织(如参加学前教育、学前教育质量、教师特征)、社区(可获得性、使用和对游戏空间的看法)和政策层面因素的讨论。虽然研究人员经常在公共卫生框架内工作,重点是中等到剧烈的身体活动,或全部(轻到剧烈)的身体活动,但这可能与幼儿的运动方式不完全一致。强调了结构化和非结构化游戏、冒险游戏和基于自然的游戏的重要性。对基础和应用科学家,临床医生和从业人员的影响。对未来工作的建议包括考虑体育活动的背景,与其他健康行为的关联,以及进一步研究人际和社区层面的因素。
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引用次数: 0
The role of resistance training in mitigating cancer-induced cachexia: A systematic review 抗阻训练在减轻癌症引起的恶病质中的作用:一项系统综述
IF 2.3 Q2 SPORT SCIENCES Pub Date : 2025-01-21 DOI: 10.1016/j.smhs.2025.01.002
Jennifer L. Horawski , Sara E. Fleszar-Pavlovic , Melissa Lopez-Pentecost , Tracy E. Crane , Madalyn G. Wheeler , Eric Kholodovsky , Thomas M. Best

Background

Cancer induced cachexia, the involuntary loss of lean body mass and adipose tissue, is a debilitating syndrome experienced in up to 80% of all cancer patients. Cachexia is associated with poor treatment outcomes including decreased quality of life, increased risk of infection, disease progression, and mortality. Recent research suggests that exercise interventions may improve cachexia; however, there is a need for comprehensive and systematic review of the literature to evaluate the role of specific interventions on cancer-induced cachexia.

Methods

We conducted a systematic review examining the efficacy of physical activity interventions, particularly resistance training, on cancer-induced cachexia outcomes. We searched seven electronic databases (PubMed, Embase, EBSCO, SCOPUS, Web of Science, PsychINFO, Cochrane) for articles published up to September 2023, yielding 7 eligible studies.

Results

Sample sizes ranged from 20 to 190 participants per study. Studies included pancreatic (n ​= ​3), head & neck (n ​= ​3), and Gastrointestinal (n ​= ​1) cancers. Mean age ranged from 51.90 to 67.1 years old and females comprised 51% of the participants. Most studies implemented resistance training interventions (73%), ranging from 3 months to 6 months in duration. Although the patterns of outcomes indicate promising results, the effect sizes for all models were small and not statistically significant.

Conclusions

The science of exercise interventions to improve outcomes in those with cancer-related cachexia is still emerging although progressive resistance training appears to be the most promising countermeasure. Authors encourage the development of high-quality, fully powered randomized controlled trials (RCTs) examining physical exercise interventions aimed at mitigating cancer-induced cachexia.
背景:癌症引起的恶病质,即不自觉的瘦体重和脂肪组织的损失,是80%的癌症患者经历的一种衰弱综合征。恶病质与不良治疗结果相关,包括生活质量下降、感染风险增加、疾病进展和死亡率增加。最近的研究表明,运动干预可能改善恶病质;然而,有必要对文献进行全面和系统的回顾,以评估特定干预措施在癌症诱导的恶病质中的作用。方法:我们进行了一项系统的综述,研究了体育活动干预,特别是抗阻训练,对癌症诱导的恶病质结局的疗效。我们检索了7个电子数据库(PubMed、Embase、EBSCO、SCOPUS、Web of Science、PsychINFO、Cochrane),检索了截至2023年9月发表的文章,得到7篇符合条件的研究。每项研究的样本量从20到190人不等。研究包括胰腺癌(n = 3)、头颈癌(n = 3)和胃肠道癌(n = 1)。平均年龄为51.90 - 67.1岁,女性占51%。大多数研究实施阻力训练干预(73%),持续时间从3个月到6个月不等。虽然结果的模式表明有希望的结果,但所有模型的效应量都很小,没有统计学意义。结论:尽管渐进式抗阻训练似乎是最有希望的对策,但改善癌症相关恶病质患者预后的运动干预科学仍在兴起。作者鼓励开展高质量、全动力的随机对照试验(RCTs),研究旨在减轻癌症引起的恶病质的体育锻炼干预。
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引用次数: 0
24-h movement guidelines and its association with health-related physical fitness in Brazilian adolescents 巴西青少年 24 小时运动指南及其与健康相关体能的关系
IF 2.3 Q2 SPORT SCIENCES Pub Date : 2024-12-28 DOI: 10.1016/j.smhs.2024.12.003
Jean Carlos Parmigiani De Marco , Tiago Rodrigues de Lima , André de Araújo Pinto , Javier Brazo-Sayavera , Andreia Pelegrini

Purpose

To examine the link between adherence to 24-h movement guidelines (isolated and combined) and muscular strength, cardiorespiratory fitness, and obesity indicators in Brazilian adolescents.

Methods

Data from 980 adolescents (14–19 years) in Florianópolis, Brazil, were analyzed. The dependent variables were body mass index (BMI), body fat, handgrip strength (HGS), maximal oxygen consumption (V˙O2max). The independent variables were physical activity (PA, IPAQ), screen time (ST), sleep (bedtime, wake-up time). Compliance was calculated for each behavior and combinations. Multiple linear regression models were employed.

Results

Overall compliance: 4.1% (boys), 4.9% (girls). Positive associations were found between PA adherence and HGS/ V˙O2max in both sexes, ST adherence and V˙O2max, and adherence to all three guidelines and V˙O2max. Girls showed positive associations between combined PA ​+ ​sleep adherence and HGS, ST ​+ ​sleep and V˙O2max, and negative associations between adherence to two guidelines and BMI. Boys exhibited a negative association between PA and body fat, positive between ST and HGS, and positive/negative between combined PA ​+ ​ST adherence and HGS/body fat. Moreover, adherence to all three guidelines associated positively with HGS.

Conclusion

Adhering to 24-h movement guidelines, alone or in combination, benefits muscular strength and cardiorespiratory fitness in Brazilian adolescents. However, simultaneous adherence did not correlate with obesity indicators.
目的研究巴西青少年坚持24小时运动指南(单独和联合)与肌肉力量、心肺健康和肥胖指标之间的联系。方法对巴西Florianópolis 980名14-19岁青少年的数据进行分析。因变量为身体质量指数(BMI)、体脂、握力(HGS)、最大耗氧量(V˙O2max)。自变量为体力活动(PA, IPAQ),屏幕时间(ST),睡眠(就寝时间,起床时间)。计算每个行为和组合的依从性。采用多元线性回归模型。结果总体依从性:男生为4.1%,女生为4.9%。两性的PA依从性与HGS/ V˙O2max呈正相关,ST依从性与V˙O2max呈正相关,三项指南的依从性与V˙O2max呈正相关。女孩的PA +睡眠依从性与HGS呈正相关,ST +睡眠依从性与V˙O2max呈正相关,而两种指南的依从性与BMI呈负相关。男孩PA与体脂呈负相关,ST与HGS呈正相关,PA + ST联合依从性与HGS/体脂呈正相关/负相关。此外,遵守所有三个指南与HGS呈正相关。结论坚持24小时运动指南,单独或联合,有益于巴西青少年的肌肉力量和心肺健康。然而,同时坚持服药与肥胖指标无关。
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引用次数: 0
Perspectives on enhancing human performance in the heat: Is the solution to simply “just add water”? 提高人体在高温下表现的观点:解决方法是否只是简单地“加水”?
IF 2.3 Q2 SPORT SCIENCES Pub Date : 2024-12-06 DOI: 10.1016/j.smhs.2024.12.001
M.L. Millard-Stafford , M.B. Brown , M.T. Wittbrodt
Human exercise performance is influenced by factors related to inherent individual characteristics along with other modifiable factors. During exercise in the heat, sweating provides the major avenue for cooling. When body water losses exceed 2% body mass, changes in physiological responses are observed in a dose-response manner. Human sweat varies in electrolyte content due to differences in ion channel re-absorption in the sweat duct. Moderate hypohydration (> 2% body mass) is associated with physical and mental performance impairments, although this depends on the environment (e.g., warm to hot) and type of exercise (e.g., endurance) or cognitive task (e.g., sustained attention, executive function, motor coordination) involved. This begs the question: Is simply adding water the optimal “solution” to improving human performance during events eliciting dehydration? This review focuses on literature applicable to athletes and military personnel during exertion in the heat. Historically, optimally formulating a sports drink to ingest during exercise has focused on appropriate levels of carbohydrate, with more recent interest spanning from higher electrolyte concentrations to amino acid formulations. Evidence to support recommendations regarding beverage bioavailability during exercise comes from studies comparing the appearance of heavy water (tagged within a beverage) in blood. Fluid delivery appears enhanced with moderately concentrated carbohydrate while electrolyte composition plays a lesser role. Despite the robust historical scientific literature related to fluid replacement, the quest for the optimal sports drink during exercise in the heat continues to generate interest considering global warming trends and the increasing numbers of new hydration-related products for exercising individuals.
人的运动表现受到与个人固有特征有关的因素以及其他可改变的因素的影响。在高温下运动时,出汗是降温的主要途径。当身体水分损失超过体重的2%时,生理反应的变化以剂量-反应方式观察到。人体汗液中电解质含量的变化是由于汗管中离子通道再吸收的差异。中度缺水(体重的2%)与身体和精神表现障碍有关,尽管这取决于所涉及的环境(如温暖到炎热)和运动类型(如耐力)或认知任务(如持续注意力、执行功能、运动协调)。这就引出了一个问题:在脱水的情况下,简单地补充水分是提高人体表现的最佳“解决方案”吗?本文综述了适用于运动员和军人在高温下运动的文献。从历史上看,运动饮料的最佳配方主要集中在适当的碳水化合物水平上,最近的兴趣从更高的电解质浓度到氨基酸配方。支持运动期间饮料生物利用度建议的证据来自比较血液中重水(标签在饮料中)外观的研究。适度浓缩的碳水化合物似乎增强了液体输送,而电解质成分的作用较小。尽管历史上有大量关于液体替代的科学文献,但考虑到全球变暖的趋势和越来越多的新的运动相关产品,在高温运动中寻找最佳运动饮料的追求继续引起人们的兴趣。
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引用次数: 0
Effects of high-intensity intermittent cross-training on maximal oxygen uptake 高强度间歇交叉训练对最大摄氧量的影响
IF 2.3 Q2 SPORT SCIENCES Pub Date : 2024-11-09 DOI: 10.1016/j.smhs.2024.11.003
Xin Liu, Katsunori Tsuji, Yuzhong Xu, Motoyuki Iemitsu, Izumi Tabata
We investigated the effects of high-intensity intermittent cross-training (HIICT) on maximal oxygen uptake (V˙O2max). The HIICT consisted of alternating intermittent 20-s treadmill running (1st, 3rd, 5th, and 7th bouts) and 20-s bicycle exercise (2nd, 4th, and 6th bouts) with a 10-s rest period. Each intensity for running and bicycling of the HIICT corresponded to an oxygen demand of ∼160% and ∼170% of the V˙O2max, respectively. Fifteen healthy young males (aged [24 ​± ​1] yrs) were randomly assigned to training (TG, n ​= ​8) and non-training control (CG, n ​= ​7) groups. The TG completed this HIICT daily 4 days/week for 6 weeks. Significant group ​× ​time interactions were observed for both the running and bicycling V˙O2max (p ​< ​0.001 each). After the training, the V˙O2max for both running ([57.4 ​± ​4.8] mL·kg−1·min−1) and bicycling ([50.6 ​± ​3.7] mL·kg−1·min−1) in the TG were significantly higher than those for running ([50.1 ​± ​3.1] mL·kg−1·min−1) and bicycling ([43.7 ​± ​3.6] mL·kg−1·min−1) in the CG, respectively (p ​< ​0.01 each). Post-hoc tests revealed a significant increase in V˙O2max for running and bicycling in the TG after the HIICT (p ​< ​0.001 each) but no significant difference in the CG. These results demonstrated that the newly developed HIICT increases the V˙O2max for both running and bicycling.
我们研究了高强度间歇交叉训练(HIICT)对最大摄氧量(V˙O2max)的影响。HIICT包括交替间歇20秒的跑步机跑步(第1、3、5和7回合)和20秒的自行车运动(第2、4和6回合),休息时间为10秒。HIICT的跑步和骑自行车的每个强度分别对应于V˙O2max的~ 160%和~ 170%的需氧量。15例健康青年男性(年龄[24±1]岁)随机分为训练组(TG, n = 8)和非训练对照组(CG, n = 7)。TG每天完成HIICT,每周4天,持续6周。跑步和骑自行车均观察到显著的组×时间相互作用V˙O2max (p <;0.001每个)。训练结束后,跑步组([57.4±4.8]mL·kg−1·min−1)和自行车组([50.6±3.7]mL·kg−1·min−1)的V˙O2max均显著高于跑步组([50.1±3.1]mL·kg−1·min−1)和自行车组([43.7±3.6]mL·kg−1·min−1)(p <;0.01每个)。事后测试显示,HIICT后TG中跑步和骑自行车的V˙O2max显著增加(p <;0.001),但CG无显著差异。这些结果表明,新开发的HIICT增加了跑步和骑自行车的V˙O2max。
{"title":"Effects of high-intensity intermittent cross-training on maximal oxygen uptake","authors":"Xin Liu,&nbsp;Katsunori Tsuji,&nbsp;Yuzhong Xu,&nbsp;Motoyuki Iemitsu,&nbsp;Izumi Tabata","doi":"10.1016/j.smhs.2024.11.003","DOIUrl":"10.1016/j.smhs.2024.11.003","url":null,"abstract":"<div><div>We investigated the effects of high-intensity intermittent cross-training (HIICT) on maximal oxygen uptake (<span><math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math></span>O<sub>2</sub>max). The HIICT consisted of alternating intermittent 20-s treadmill running (1<sup>st</sup>, 3<sup>rd</sup>, 5<sup>th</sup>, and 7<sup>th</sup> bouts) and 20-s bicycle exercise (2<sup>nd</sup>, 4<sup>th</sup>, and 6<sup>th</sup> bouts) with a 10-s rest period. Each intensity for running and bicycling of the HIICT corresponded to an oxygen demand of ∼160% and ∼170% of the <span><math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math></span>O<sub>2</sub>max, respectively. Fifteen healthy young males (aged [24 ​± ​1] yrs) were randomly assigned to training (TG, <em>n</em> ​= ​8) and non-training control (CG, <em>n</em> ​= ​7) groups. The TG completed this HIICT daily 4 days/week for 6 weeks. Significant group ​× ​time interactions were observed for both the running and bicycling <span><math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math></span>O<sub>2</sub>max (<em>p</em> ​&lt; ​0.001 each). After the training, the <span><math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math></span>O<sub>2</sub>max for both running ([57.4 ​± ​4.8] mL·kg<sup>−1</sup>·min<sup>−1</sup>) and bicycling ([50.6 ​± ​3.7] mL·kg<sup>−1</sup>·min<sup>−1</sup>) in the TG were significantly higher than those for running ([50.1 ​± ​3.1] mL·kg<sup>−1</sup>·min<sup>−1</sup>) and bicycling ([43.7 ​± ​3.6] mL·kg<sup>−1</sup>·min<sup>−1</sup>) in the CG, respectively (<em>p</em> ​&lt; ​0.01 each). Post-hoc tests revealed a significant increase in <span><math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math></span>O<sub>2</sub>max for running and bicycling in the TG after the HIICT (<em>p</em> ​&lt; ​0.001 each) but no significant difference in the CG. These results demonstrated that the newly developed HIICT increases the <span><math><mrow><mover><mi>V</mi><mo>˙</mo></mover></mrow></math></span>O<sub>2</sub>max for both running and bicycling.</div></div>","PeriodicalId":33620,"journal":{"name":"Sports Medicine and Health Science","volume":"7 3","pages":"Pages 185-189"},"PeriodicalIF":2.3,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143139737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physical activity, exercise, and mental health of healthy adolescents: A review of the last 5 ​years 健康青少年的身体活动、锻炼和心理健康:近5年综述
IF 2.3 Q2 SPORT SCIENCES Pub Date : 2024-10-18 DOI: 10.1016/j.smhs.2024.10.003
Eva Ruiz-Ranz , Iván Asín-Izquierdo
The mental health of adolescents is a priority for successful development. Physical activity (PA) and exercise can have effects on the mental health of adolescents. This review analysed the effect that physical exercise interventions can have on the mental health of healthy adolescents between 10 and 19 years of age. The search was carried out in four databases. PubMed, Web of Science, Scopus and SportDiscuss, were searched up to December 31, 2022, following the general model. Eleven studies were selected, with a total sample of 23 ​681 participants in 2 435 studies published in the last 5 years involving healthy adolescents. The search process and review of the articles was performed by independent expert investigators. The risk-of-bias and the methodological quality were analysed using the Cochrane scale. The limited and heterogeneous studies conducted so far do not clearly establish the benefits of PA on adolescents’ mental health. However, some PA interventions seem to improve subjective well-being, self-esteem, physical and mental well-being, anxiety, lifestyle, emotional intelligence, depressive mood, and perceived benefit and confidence in healthy adolescents. It is important to design an effective and appropriate physical exercise programme that can be implemented for adolescents to achieve significant effects on their mental health. Studies that did not implement an appropriate exercise program with improvements in adolescent physical fitness showed no changes in psychological variables. Further research is needed to clearly establish that exercise programmes have positive effects on mental health in healthy adolescents.
青少年的心理健康是成功发展的优先事项。体育活动(PA)和运动可以对青少年的心理健康产生影响。这篇综述分析了体育锻炼干预对10 - 19岁健康青少年心理健康的影响。在四个数据库中进行了搜索。PubMed、Web of Science、Scopus和SportDiscuss的检索截止到2022年12月31日,遵循一般模式。选择了11项研究,在过去5年发表的涉及健康青少年的2435项研究中,总共有23681名参与者。文章的检索过程和审查由独立的专家调查员进行。使用Cochrane量表分析偏倚风险和方法学质量。迄今为止进行的有限和异质性的研究并没有清楚地确定PA对青少年心理健康的益处。然而,一些PA干预似乎改善了健康青少年的主观幸福感、自尊、身心健康、焦虑、生活方式、情商、抑郁情绪以及感知利益和信心。重要的是要设计一项有效和适当的体育锻炼方案,可以为青少年实施,以对他们的心理健康产生重大影响。没有实施适当的锻炼计划以改善青少年身体健康的研究显示,心理变量没有变化。需要进一步的研究来明确确定运动方案对健康青少年的心理健康有积极影响。
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引用次数: 0
Mechanisms of muscle repair after peripheral nerve injury by electrical stimulation combined with blood flow restriction training 电刺激联合限血训练对周围神经损伤后肌肉修复的机制
IF 2.3 Q2 SPORT SCIENCES Pub Date : 2024-10-11 DOI: 10.1016/j.smhs.2024.10.002
Xiaolei Chu , Jiaojiao Sun , Jiajia Liang , Wenjie Liu , Zheng Xing , Qi Li , Qingwen Li
This review elucidates the impact of electrical stimulation (ES) and blood flow restriction (BFR) training on muscle function. ES induces a transformation in muscle fibers type by rearranging myosin heavy chain isoform patterns. Additionally, it influences muscle protein synthesis and degradation through specific signaling pathways such as protein kinase B/mechanistic target of rapamycin (Akt/mTOR), as well as via autophagy and the ubiquitin-proteasome system, thereby effectively maintaining muscle mass. BFR, on the other hand, restricts muscle blood flow, leading to metabolic products accumulation and localized hypoxia, which not only promotes the recruitment of fast-twitch fibers but also activates the mTOR signaling pathway, enhancing muscle protein synthesis. The combination of ES and BFR synergistically facilitates muscle protein synthesis through the mTOR pathway, thereby accelerating the recovery of muscle function following peripheral nerve injury.
本文综述了电刺激(ES)和血流限制(BFR)训练对肌肉功能的影响。ES通过重新排列肌球蛋白重链异构体模式诱导肌纤维类型的转变。此外,它还通过蛋白激酶B/雷帕霉素机制靶点(Akt/mTOR)等特定信号通路,以及自噬和泛素-蛋白酶体系统影响肌肉蛋白的合成和降解,从而有效地维持肌肉质量。另一方面,BFR限制肌肉血流,导致代谢产物积累和局部缺氧,这不仅促进了快肌纤维的募集,还激活了mTOR信号通路,增强了肌肉蛋白质的合成。ES与BFR联合作用,通过mTOR通路协同促进肌肉蛋白合成,从而加速周围神经损伤后肌肉功能的恢复。
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引用次数: 0
Strength development following a six-week risk reduction athletic development training program in men and women 在男性和女性进行为期六周的风险降低运动发展训练项目后的力量发展
IF 2.3 Q2 SPORT SCIENCES Pub Date : 2024-09-12 DOI: 10.1016/j.smhs.2024.09.004
Christopher J. Cleary , Krisha Crane , Lisa M. Vopat , Bryan G. Vopat , Ashley A. Herda
This study retrospectively evaluated data from an athlete management system on the impact of a 6-week, 12-session risk-reduction athletic development training program on maximal isometric strength in post-rehabilitative and healthy men and women. Maximal isometric quadriceps and hamstrings strength were evaluated bilaterally before and after the training program. Out of 55 athletes that had participated in the program, a total of 37 athletes' (13–28 years old) recorded outcomes were utilized in analyses. Thirty-one athletes had undergone rehabilitation (post-rehabilitative athletes) after orthopedic knee surgeries. Six athletes with no previous surgeries performed (healthy athletes) also completed the 6-week program. Repeated measures analyses of variance (leg × time) assessed changes in quadriceps and hamstrings strength at an alpha of p ​≤ ​0.05. There was a main effect for time where the post-rehabilitative athletes’ quadriceps and hamstrings strength increased by (mean difference ​± ​standard error) (4.2 ​± ​0.7) kg (p ​< ​0.01) and (4.5 ​± ​0.9) kg (p ​< ​0.01) respectively, with legs (operative [OP]) and non-operative [NOP]) combined. With time points combined, the OP limb was weaker than the NOP limb for quadriceps strength by (2.9 ​± ​0.7) kg (p ​< ​0.01) with no differences in hamstrings strength. For the healthy athletes, there were no changes for quadriceps strength and hamstring strength improved across time by (5.3 ​± ​1.4) kg (p ​= ​0.01) with legs combined.
In conclusion, there were improvements in post-rehabilitative and healthy athletes’ isometric strength after the training program. However, between-limb strength asymmetries were still apparent in the post-rehabilitation cohort.
本研究回顾性评估了来自运动员管理系统的数据,分析了6周、12期降低风险的运动发展训练计划对康复后和健康男性和女性最大等长力量的影响。最大等长股四头肌和腘绳肌力量在训练计划前后进行评估。在参与该项目的55名运动员中,共有37名运动员(13-28岁)的记录结果被用于分析。31名运动员在膝关节矫形手术后接受了康复治疗。6名以前没有做过手术的运动员(健康运动员)也完成了为期6周的项目。重复测量方差分析(腿×时间)评估股四头肌和腘绳肌力量的变化,alpha值为p≤0.05。在康复后运动员股四头肌和腘绳肌力量增加的时间上存在主效应(平均差±标准误差)(4.2±0.7)kg (p <;0.01)和(4.5±0.9)kg (p <;0.01),腿部(手术[OP]和非手术[NOP])合并。结合时间点,OP肢的股四头肌力量弱于NOP肢(2.9±0.7)kg (p <;0.01),腘绳肌力量无差异。对于健康运动员,股四头肌力量和腘绳肌力量随时间的变化没有变化(5.3±1.4)kg (p = 0.01)。综上所述,训练计划对康复后和健康运动员的等长肌力有改善。然而,在康复后队列中,肢间力量不对称仍然很明显。
{"title":"Strength development following a six-week risk reduction athletic development training program in men and women","authors":"Christopher J. Cleary ,&nbsp;Krisha Crane ,&nbsp;Lisa M. Vopat ,&nbsp;Bryan G. Vopat ,&nbsp;Ashley A. Herda","doi":"10.1016/j.smhs.2024.09.004","DOIUrl":"10.1016/j.smhs.2024.09.004","url":null,"abstract":"<div><div>This study retrospectively evaluated data from an athlete management system on the impact of a 6-week, 12-session risk-reduction athletic development training program on maximal isometric strength in post-rehabilitative and healthy men and women. Maximal isometric quadriceps and hamstrings strength were evaluated bilaterally before and after the training program. Out of 55 athletes that had participated in the program, a total of 37 athletes' (13–28 years old) recorded outcomes were utilized in analyses. Thirty-one athletes had undergone rehabilitation (post-rehabilitative athletes) after orthopedic knee surgeries. Six athletes with no previous surgeries performed (healthy athletes) also completed the 6-week program. Repeated measures analyses of variance (leg × time) assessed changes in quadriceps and hamstrings strength at an alpha of <em>p</em> ​≤ ​0.05. There was a main effect for time where the post-rehabilitative athletes’ quadriceps and hamstrings strength increased by (mean difference ​± ​standard error) (4.2 ​± ​0.7) kg (<em>p</em> ​&lt; ​0.01) and (4.5 ​± ​0.9) kg (<em>p</em> ​&lt; ​0.01) respectively, with legs (operative [OP]) and non-operative [NOP]) combined. With time points combined, the OP limb was weaker than the NOP limb for quadriceps strength by (2.9 ​± ​0.7) kg (<em>p</em> ​&lt; ​0.01) with no differences in hamstrings strength. For the healthy athletes, there were no changes for quadriceps strength and hamstring strength improved across time by (5.3 ​± ​1.4) kg (<em>p</em> ​= ​0.01) with legs combined.</div><div>In conclusion, there were improvements in post-rehabilitative and healthy athletes’ isometric strength after the training program. However, between-limb strength asymmetries were still apparent in the post-rehabilitation cohort.</div></div>","PeriodicalId":33620,"journal":{"name":"Sports Medicine and Health Science","volume":"7 4","pages":"Pages 280-284"},"PeriodicalIF":2.3,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preschool-aged children 24-hour movement behaviours before and during COVID-19 学龄前儿童在 COVID-19 之前和期间的 24 小时运动行为
IF 2.3 Q2 SPORT SCIENCES Pub Date : 2024-09-05 DOI: 10.1016/j.smhs.2024.09.001
Mingming Cui , Xiaojuan Wang , Zhaoxu Lu , Anthony D. Okely , Katharina Kariippanon , Ellie K. Taylor , Ting Zhang , Hongyan Guan
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affected health, economies, and lifestyles, but little is known about its impact on children. We aimed to investigate changes in 24-hour (h) movement behaviours of pre-school children before and during COVID-19, and factors that influenced these. Children aged 3–6 years were recruited in Beijing in 2019, and their movement behaviours over 24 ​h assessed by questionnaire, as part of the International Study of Movement Behaviors in the Early Years (SUNRISE) study. We conducted the survey again during COVID-19, and compared the children’s movement behaviours before and during COVID-19 and associated factors. Overall, 196 parents completed the survey at both time points. The percentage of children meeting movement guidelines decreased during the pandemic (p ​< ​0.01). Total physical activity decreased less among children getting good quality sleep or with more adults in the household (p ​< ​0.01). Children who were not cared for primarily by their mother had a greater decrease in moderate to vigorous intensity physical activity (p ​= ​0.02), but the decrease was smaller among children whose parents used the internet to support their physical activity and/or screen time (p ​< ​0.05). Children who used electronic screen devices in the 2 ​h before bedtime or whose parents reported body temperature in webchats had a greater increase in sedentary screen time (p ​< ​0.05). Children spending more time outdoors showed a smaller decrease in sleep (p ​< ​0.01). Overall, children’s movement behaviours changed significantly during the pandemic.
由严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)引起的 2019 年冠状病毒病(COVID-19)大流行影响了健康、经济和生活方式,但人们对其对儿童的影响知之甚少。我们的目的是调查学龄前儿童在 COVID-19 之前和期间 24 小时运动行为的变化,以及影响这些变化的因素。我们于2019年在北京招募了3-6岁的儿童,并通过问卷调查评估了他们在24小时内的运动行为,这是国际幼儿运动行为研究(SUNRISE)的一部分。我们在 COVID-19 期间再次进行了调查,并比较了儿童在 COVID-19 之前和期间的运动行为及相关因素。共有 196 名家长在两个时间点完成了调查。在大流行期间,符合运动准则的儿童比例有所下降(p < 0.01)。在睡眠质量较好或家中有较多成人的儿童中,总体力活动量的下降幅度较小(p < 0.01)。不是主要由母亲照顾的儿童的中等强度到剧烈强度的体力活动量减少较多(p = 0.02),但父母使用互联网支持其体力活动和/或屏幕时间的儿童的体力活动量减少较少(p < 0.05)。在睡前 2 小时使用电子屏幕设备或父母在网络聊天中报告体温的儿童,其久坐屏幕时间增加较多(p < 0.05)。户外活动时间较多的儿童睡眠减少的幅度较小(p < 0.01)。总体而言,儿童的运动行为在大流行期间发生了显著变化。
{"title":"Preschool-aged children 24-hour movement behaviours before and during COVID-19","authors":"Mingming Cui ,&nbsp;Xiaojuan Wang ,&nbsp;Zhaoxu Lu ,&nbsp;Anthony D. Okely ,&nbsp;Katharina Kariippanon ,&nbsp;Ellie K. Taylor ,&nbsp;Ting Zhang ,&nbsp;Hongyan Guan","doi":"10.1016/j.smhs.2024.09.001","DOIUrl":"10.1016/j.smhs.2024.09.001","url":null,"abstract":"<div><div>The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affected health, economies, and lifestyles, but little is known about its impact on children. We aimed to investigate changes in 24-hour (h) movement behaviours of pre-school children before and during COVID-19, and factors that influenced these. Children aged 3–6 years were recruited in Beijing in 2019, and their movement behaviours over 24 ​h assessed by questionnaire, as part of the International Study of Movement Behaviors in the Early Years (SUNRISE) study. We conducted the survey again during COVID-19, and compared the children’s movement behaviours before and during COVID-19 and associated factors. Overall, 196 parents completed the survey at both time points. The percentage of children meeting movement guidelines decreased during the pandemic (<em>p</em> ​&lt; ​0.01). Total physical activity decreased less among children getting good quality sleep or with more adults in the household (<em>p</em> ​&lt; ​0.01). Children who were not cared for primarily by their mother had a greater decrease in moderate to vigorous intensity physical activity (<em>p</em> ​= ​0.02), but the decrease was smaller among children whose parents used the internet to support their physical activity and/or screen time (<em>p</em> ​&lt; ​0.05). Children who used electronic screen devices in the 2 ​h before bedtime or whose parents reported body temperature in webchats had a greater increase in sedentary screen time (<em>p</em> ​&lt; ​0.05). Children spending more time outdoors showed a smaller decrease in sleep (<em>p</em> ​&lt; ​0.01). Overall, children’s movement behaviours changed significantly during the pandemic.</div></div>","PeriodicalId":33620,"journal":{"name":"Sports Medicine and Health Science","volume":"7 4","pages":"Pages 249-255"},"PeriodicalIF":2.3,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Sports Medicine and Health Science
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