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Diagnostic aspects of female pyometra (review information) 女性子宫积脓的诊断要点(复习资料)
Pub Date : 2021-12-09 DOI: 10.33245/2310-4902-2021-168-2-18-36
P. Skliarov, V. Pyatibrat
Pyometra is one of the most common and dangerous diseases in bitches, and its complicated course requires immediate treatment and, consequently, the need for highly informative, objective and reliable diagnostic approaches to recognition at the earliest possible stages of the disease. However, the complexity of the pathogenesis, staging and polysymptomatic pyometra cause certain problems in making the correct diagnosis and, consequently, the provision of adequate therapy. Despite the fact that today a number of methods for diagnosing pyometra in bitches have been proposed, none of them fully meets the needs of modern practical veterinary medicine. The purpose of the study was to conduct a systematic analysis and generalization of scientific publications on methods, criteria and approaches for the diagnosis of pyometra in bitches. Research methods such as search, selection, processing and analysis of literature sources in the field of research according to the rules for systematic reviews of the literature are used. Based on the analysis of data from selected articles, conclusions were made about the state of the chosen area of research – the effectiveness of methods, criteria and approaches for the diagnosis of pyometra in females. It is important in the diagnosis of pyometra to detect not only pathognomonic signs, but also early sepsis and the symptom complex of multiple organ failure. Therefore, the diagnosis of pyometra in bitches is made comprehensively, taking into account the anamnesis, clinical examination of animals, laboratory tests of blood and exudate. The standard package of diagnostic measures is based on the analysis of anamnesis data, determination of typical clinical signs, assessment of laboratory parameters and results of ultrasound examination. However, in practical veterinary medicine, the diagnosis of pyometra in bitches is usually made on the basis of anamnestic data and their revision, clinical examination and ultrasound diagnosis. When recognizing pyometra, it is necessary to keep in mind other possible causes of vaginal discharge and / or uterine enlargement, accompanied by a violation of the general condition of the animal, which should be considered as a differential diagnosis. Current research trends indicate promising development of biomarkers based on serum and endometrial transcripts for early diagnosis, prediction and differentiation of pyometra.Key words: dogs, endometritis purulenta, methods, criteria and diagnostic approaches.
脓脓症是母狗中最常见和最危险的疾病之一,其复杂的病程需要立即治疗,因此需要高度翔实、客观和可靠的诊断方法,以便在疾病的最早阶段进行识别。然而,复杂的发病机制、分期和多症状性脓膜炎在做出正确诊断和提供适当治疗方面存在一定的问题。尽管今天已经提出了许多诊断母狗脓脓的方法,但它们都不能完全满足现代实用兽医的需要。本研究的目的是对有关母狗脓脓症的诊断方法、标准和途径的科学文献进行系统的分析和概括。按照文献系统综述的规则,对研究领域的文献来源进行检索、选择、处理和分析等研究方法。根据所选文章的数据分析,得出结论关于所选研究领域的状态-方法,标准和方法的有效性诊断女性子宫脓膜。脓膜炎的诊断不仅要注意病理征象,而且要注意早期脓毒症和多器官功能衰竭的症状复合体。因此,对母狗脓脓症的诊断应综合考虑记忆、动物临床检查、血液和渗出液实验室检查。诊断措施的标准包是基于对记忆数据的分析、典型临床体征的确定、实验室参数的评估和超声检查结果。然而,在实际兽医中,对母狗脓膜炎的诊断通常是根据记忆资料及其修订、临床检查和超声诊断来进行的。在识别脓膜肿大时,有必要记住阴道分泌物和/或子宫肿大的其他可能原因,并伴有违反动物一般状况的情况,这应被视为鉴别诊断。目前的研究趋势表明,基于血清和子宫内膜转录物的生物标志物在脓膜瘤的早期诊断、预测和鉴别方面有很大的发展前景。关键词:犬,脓性子宫内膜炎,方法,标准及诊断途径。
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引用次数: 0
Study of Zinc and Manganese content in blood serum, feathers and claws in 14-, 21- and 28-days old broiler chickens with perosis 14日龄、21日龄和28日龄枯死肉鸡血清、羽毛和爪子中锌、锰含量的研究
Pub Date : 2021-12-09 DOI: 10.33245/2310-4902-2021-168-2-108-116
V. Sakara, A. Melnyk, L. Bogatko, B. Bilyk
Culling due to poor condition, weight loss, mortalityand, as a result, economic losses due to perosa, accordingto various estimates, 1-5% of the group of birds. Due to thedysfunction of the limbs, the bird can suffer from a numberof diseases. Lack of essential nutrients play an important rolein the development of perosis in poultry. Often in farms dueto cost savings, reduce the cost of feed for broilers, which inturn can lead to metabolic disorders in poultry. Therefore, thediagnosis of these disorders requires new approaches. Modernscience is increasingly inclined to non-invasive diagnosis ofmetabolic pathologies. In human medicine, nails and hair areused to study persistent micronutrient deficiencies. And inveterinary medicine in the study of micronutrient deficienciesas a method of non-invasive diagnosis using animal hair.According to the results of our research, theconcentrations of microelements (Zn, Mn) in the feathers of14, 21 and 28-days-old clinically healthy and feathery broilerchickens were determined. On day 14 of the disease, theconcentration of Zinc and Manganese in broiler chickens withperosis was 65.6 ± 2.73 and 17.4 ± 0.79 μg / g, which wasprobably higher than in clinically healthy birds 46.5 ± 1.57(p <0.001) and 10.9 ± 0.80 (p <0.001) μg / g. Analyzing the indicators of micronutrients in the clawsof patients with feathers of broiler chickens of 28 days ofage, the content of Manganese was 10.2 ± 0.51 μg / g, whichis probably less than in clinically healthy birds 15.7 ± 0.97μg / g (p < 0.01). The concentration of zinc in the claws ofhealthy birds is 127.6 ± 3.65 μg / g, which tended to increasecompared to that in healthy birds - 98.3 ± 5.40 μg / g.The results of the analysis show that in birds with signs ofperosis, Zinc and Manganese accumulate in higher concentrations in the feathers compared to clinically healthy chickens. Inturn, the concentration of these elements in the claws in chickens with feathers relative to healthy birds of the group decreases.Key words: trace elements, non-invasive diagnostics,metabolic pathologies, avian.
根据各种估计,由于状况不佳、体重减轻、死亡以及由此造成的经济损失而进行的扑杀,占该鸟类总数的1-5%。由于四肢的功能障碍,这种鸟可能会患上许多疾病。缺乏必需的营养物质在家禽的骨质疏松中起着重要的作用。通常在农场,由于节省成本,降低肉鸡的饲料成本,这反过来可能导致家禽代谢紊乱。因此,这些疾病的诊断需要新的方法。现代科学越来越倾向于对代谢病理进行无创诊断。在人类医学中,指甲和头发被用来研究持续的微量营养素缺乏。并在兽医学中研究利用动物毛发对微量营养素缺乏症进行无创诊断的方法。根据本研究结果,测定了14、21和28日龄临床健康肉鸡和长羽肉鸡羽毛中微量元素(Zn、Mn)的含量。发病第14天,坏死肉鸡体内锌、锰的浓度分别为65.6±2.73和17.4±0.79 μg / g,可能高于临床健康肉鸡的46.5±1.57(p <0.001)和10.9±0.80 (p <0.001) μg / g。分析28日龄肉鸡带毛患者爪中微量元素指标,锰含量为10.2±0.51 μg / g;可能低于临床健康禽15.7±0.97μg / g (p < 0.01)。健康鸡爪中锌的浓度为127.6±3.65 μg / g,比健康鸡爪中锌的浓度(98.3±5.40 μg / g)有增加的趋势。分析结果表明,与临床健康鸡相比,有骨质疏松迹象的鸡的羽毛中锌和锰的积累浓度更高。相反,长羽毛的鸡爪中这些元素的浓度相对于对照组的健康鸡有所下降。关键词:微量元素;无创诊断;代谢病理;
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引用次数: 0
Pharmacotherapy of knemidocoptosis in budgerigars 虎牙膝关节下垂的药物治疗
Pub Date : 2021-12-09 DOI: 10.33245/2310-4902-2021-168-2-89-96
N. Kozii, V. Shahanenko, R. Shahanenko, S. Rublenko, N. Avramenko
The article presents a study of the pharmacotherapeutic efficacy of drugs of etiotropic action Ivermikol drops and Aversectin ointment for cnemidocoptosis in budgerigars. Treatment was directed to the study of etiotropic therapy of acaricidal drugs in relation to the causative agents of invasion in sick birds and in the environment. Extensibility and intensity (EE and IE) of the drugs were assessed on the 6th, 22nd and 36th days after the treatment. A study group of budgies suffering from knemidocoptosis was given the following treatment regimen: ivermicol drops, chlorhexidine and Perlen multivitamized grain mixture for food. According to the treatment, on the 6th day in budgies, the extensibility was 0 %. On the 22nd day of treatment in 4 parrots during microscopic examination of scrapings from the affected areas, Knemidocoptes mites were found. Thus, the extensibility of ivermicol drops was 33.3 %. On the 36th day, the extensibility of the treatment of parrots with ivermicol drops was 100 %. Thus, the results obtained make it possible to recommend the indicated scheme for the treatment of ornamental birds for knemidocoptosis. Thuse of the treatment of sick budgerigars according to a different scheme (aversectin ointment, chlorhexidine and multivitamized Perlen grain mixture for nutrition) also proved to be effective. However, on the 22nd day of treatment, microscopic examination of scrapings from the affected areas revealed Knemidokoptes mites in 5 parrots, thus, the extensibility of aversectin ointment was 16.7 %. On the 36th day of treatment in parrots of the control group, which were treated with aversectin ointment, the EE of treatment was 66 %, since 2 out of 6 parrots remained sick, which required further treatment. The dynamics of the EE and IE of ivermicol drops and avesectin ointments on the 6th, 22nd, and 36th days of the study indicate the highest therapeutic efficacy of ivermicol drops. Thus, the use of ivermicol drops as a means of etiotropic action in the cinemidocoptosis of budgerigars is effective.Key words: scabies, treatment, knemidocoptosis, parrots, Cnemidocoptes pilae, acaricidalpreparations, ivermicoldrops, aversectinointment.
本文研究了致病因药物伊维蜜滴剂和阿维菌素软膏对虎皮猴中枢性眼病的治疗效果。治疗的方向是研究杀螨药物对病禽和环境中入侵病原体的致因性治疗。分别于给药后第6、22、36天评价药物的可展性和强度(EE、IE)。采用依维米考滴剂、氯己定、Perlen复合维生素杂粮作食疗,对实验组虎皮松弛症虎皮鹦鹉进行治疗。根据处理,在第6天,虎皮鹦鹉的伸长率为0%。治疗第22天,对4只鹦鹉患处刮痧进行显微镜检查,检出革膝螨。依维霉素滴剂的延展性为33.3%。第36天,依维霉素滴剂对鹦鹉治疗的延展性为100%。因此,所获得的结果使推荐观赏鸟类膝关节下垂的指示治疗方案成为可能。另一种治疗虎皮鹦鹉病的方案(阿维切素软膏、氯己定和多种维生素的麦麸混合营养品)也证明是有效的。然而,在治疗第22天,显微镜检查患处刮痧,发现有5只鹦鹉有膝裂螨,因此,aversectin软膏的延伸性为16.7%。在治疗第36天,对照组鹦鹉使用阿维切素软膏治疗,治疗EE为66%,因为6只鹦鹉中有2只仍然患病,需要进一步治疗。依维霉素滴剂和阿维维素软膏在研究第6、22和36天的EE和IE动态变化表明,依维霉素滴剂的治疗效果最高。因此,使用依维霉素滴剂作为一种致病因作用的手段对虎皮猴的电影细胞凋亡是有效的。关键词:疥疮,治疗,膝癣,鹦鹉,膝癣,杀螨制剂,虫眼滴剂,抗虫软膏
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引用次数: 0
Supply of iron in piglets with colostrum/milk of sows using iron (IV) clatrochelate 用螯合铁(IV)在仔猪初乳/母猪乳中添加铁
Pub Date : 2021-12-09 DOI: 10.33245/2310-4902-2021-168-2-176-182
I. Derkach, S. Derkach, V. Dukhnytsky, I. Fritsky, M. Plutenko
Many works of both Ukrainian scientists and foreign are devoted to the study of the prevention of iron deficiency anemia in piglets as one of the most common non-communicable diseases of pigs. However, the development of new effective antianemic drugs is still relevant today. We have previously proposed a scheme for the prevention of iron deficiency anemia, based on intramuscular parallel administration of solutions of iron (IV) clatrochelate and cyanocobalaminе to pregnant sows 14 and 7 days before the expected farrowing. This scheme was effective in the absence of stillbirth and clinical signs of anemia in piglets. The aim of our next study was to investigate the content of iron in the milk of sows using iron (IV) clatrochelate during pregnancy. To achieve this goal, 2 groups of sows (hybrids of Landrace and Great White breeds) were formed during their pregnancy and kept with suckling piglets - control and experimental, 5 animals in each. Sows in the experimental group were injected twice (14 and 7 days before expected farrowing) with 10 ml of 10% iron (IV) clatrochelate solution and cyanocobalaminе solution (at the dose recommended by official instructions) twice during pregnancy. Sows of the control group were injected with isotonic sodium chloride solution in conventional doses. During the experiment, the sows of the experimental group during pregnancy (after drug administration) and during the feeding of piglets did not differ in behavior and general condition from the sows of the control group. The study of the dynamics of hemoglobin and morphological parameters of the blood of sows in the control and experimental groups did not reveal significant differences. The content of iron in colostrum / milk of sows of the experimental group during the first seven days after administration was significantly higher compared to the control: 1 day 1.5 times, 4 days 2.1 times and 7 days 2.8 times. Therefore, the proposed scheme for the prevention of iron deficiency anemia in piglets is highly efficientand based on the intake of iron with colostrum/milk of sows.Key words: anemia, injection, macrobicyclic complex, prophylaxis, pigs, cyanocobalaminе.
乌克兰科学家和外国科学家的许多工作都致力于研究预防仔猪缺铁性贫血,这是猪最常见的非传染性疾病之一。然而,开发新的有效的抗贫血药物在今天仍然具有重要意义。我们之前提出了一种预防缺铁性贫血的方案,基于肌内平行给药铁(IV)螯合铁和氰钴胺,妊娠母猪在预期分娩前14天和7天。该方案在仔猪无死产和贫血临床症状的情况下有效。我们下一项研究的目的是研究妊娠期间使用氯螯合铁(IV)的母猪奶中的铁含量。为了实现这一目标,在母猪怀孕期间形成两组母猪(长白种和大白种的杂交母猪),并与哺乳仔猪一起饲养-对照和实验,每组5头。试验组母猪在妊娠期间(预产期前14天和7天)分别注射10%氯螯合铁溶液和氰钴胺溶液10 ml(按官方说明书推荐剂量)。对照组母猪按常规剂量注射等渗氯化钠溶液。在试验期间,试验组母猪在妊娠期(给药后)和仔猪饲养期间的行为和一般状况与对照组母猪无显著差异。对对照组和试验组母猪血液中血红蛋白动态和形态参数的研究没有发现显著差异。试验组母猪初乳/乳铁含量在给药后第7天显著高于对照组:第1天1.5倍,第4天2.1倍,第7天2.8倍。因此,所提出的预防仔猪缺铁性贫血的方案是高效的,并且基于母猪初乳/乳中铁的摄入量。关键词:贫血,注射,大环复合物,预防,猪,氰钴胺
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引用次数: 1
Influence of non-ionizing radiation on protein metabolism in chickens 非电离辐射对鸡蛋白质代谢的影响
Pub Date : 2021-12-09 DOI: 10.33245/2310-4902-2021-168-2-136-146
S. Prosyanyi, V. Horiuk
In practical terms, the idea of using an artificial magnetic field is of particular interest, which corresponds in its physical characteristics to the geomagnetic field of the Earth to combat the negative effects of hypogeomagnetic field. Further development of this idea is associated with the use and selection of hypo-, hypermagnetic fields acting on the body with experimental pathology. In this regard, the issue of influence of different duration of irradiation with an alternating pulsed electromagnetic field of ultra-low frequency (APEMF ULF) on the indicators that characterize metabolic processes in the body is insufficiently clarified. Therefore, the aim of research has been to study the effect of alternating pulsed electromagnetic field of ultra-low frequency on protein content and protein metabolism in the body of experimental chickens of the Dominant D959 cross. For this purpose, four experimental and control groups of 120-day-old chickens have been formed – 20 heads in each. The poultry has been kept in a specially equipped room with an alternating pulsed electromagnetic field of ultra-low frequency. The total protein content has been determined by the biuret method; protein fractions (albumins, globulins: alpha-1, alpha-2, beta, gamma) – by diffuse polyacrylamide gel (PAAG) electrophoresis; the content of creatinine, urea and uric acid has been performed by spectrophotometry using standard techniques. According to the results of research, it has been established that by selecting different regimens and duration of action of APEMF ULF, it is possible to influence protein metabolism in the body of chickens. Thus, on the 80th day of continuous irradiation of experimental chickens with APEMF ULF, regardless of the level of protein in the diet, in their blood revealed an increase in total protein, the relative content of globulin fraction mainly due to γ-globulins, and an increase in creatinine, urea and uric acids. When the period of continuous irradiation has been increased to 5 months, a negative effect on protein metabolism has been revealed, which has been manifested by a decrease in total protein content, relative albumin content, decrease in creatinine, urea and uric acid in the serum of experimental chickens. The combination of long-term (for 150 days) daily 60 minutes with weekly intervals of irradiation of chickens with APEMF ULF and their feeding with a 15% increase in protein levels in the diet caused a stimulating effect on protein metabolism and resistance of experimental chickens, with increasing, the relative content of globulins due to the γ-globulin fraction, as well as the main indicators of protein metabolism – creatinine, urea, uric acid.Key words: electromagnetic influence, chicken of Dominant D959 cross, total protein, protein fractions, creatinine, urea, uric acid.
实际上,使用人工磁场的想法特别有趣,它的物理特性与地球的地磁场相对应,以对抗次地磁场的负面影响。这一观点的进一步发展与使用和选择作用于实验病理体的低、高磁场有关。在这方面,超低频率交变脉冲电磁场(APEMF ULF)照射的不同持续时间对表征体内代谢过程的指标的影响问题没有得到充分澄清。因此,本研究旨在研究超低频交变脉冲电磁场对D959优势杂交试验鸡体内蛋白质含量和蛋白质代谢的影响。为此,将120日龄鸡分成4个实验组和对照组,每组20头。这些家禽被饲养在一个特别装备的房间里,房间里有超低频率的交变脉冲电磁场。用双缩脲法测定总蛋白含量;蛋白质组分(白蛋白,球蛋白:α -1, α -2, β, γ) -通过弥漫聚丙烯酰胺凝胶(PAAG)电泳;采用标准技术分光光度法测定了肌酐、尿素和尿酸的含量。根据研究结果,已经确定通过选择不同的APEMF ULF方案和作用时间,可以影响鸡体内的蛋白质代谢。由此可见,在APEMF ULF连续照射实验鸡第80天,无论饲粮中蛋白质水平如何,其血液中总蛋白、以γ-球蛋白为主的球蛋白部分的相对含量均有所增加,肌酐、尿素和尿酸均有所增加。当持续辐照时间延长至5个月时,对试验鸡的蛋白质代谢产生负面影响,表现为血清总蛋白含量、相对白蛋白含量降低,肌酐、尿素和尿酸降低。长期(150天)每天60分钟、每隔一周对APEMF ULF进行照射,并在饲粮中增加15%的蛋白质水平,对试验鸡的蛋白质代谢和抗性产生刺激作用,由于γ-球蛋白部分,球蛋白的相对含量以及蛋白质代谢的主要指标-肌酐、尿素、尿酸均有所增加。关键词:电磁影响,优势D959杂交鸡,总蛋白,蛋白质组分,肌酐,尿素,尿酸。
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引用次数: 0
Serological monitoring of brucellosis among wild boars in Ukraine during 2019–2020 2019-2020年乌克兰野猪布鲁氏菌病血清学监测
Pub Date : 2021-12-09 DOI: 10.33245/2310-4902-2021-168-2-49-56
H. Aliekseieva, A. Pyskun, I. Piankivska, O. Polishchuk, H. Mietolapova
The key to the successful development of animalhusbandry is the epizootic welfare of the country. Forimplementation the set of preventive measures it is requiresa perfect system for diagnosing infectious diseases, includingbrucellosis. Despite the fact that Ukraine is consideredofficially free from this zoonosis among farm animals, thesituation regarding it in the wild fauna of our country remainsinsufficiently studied.This article presents the results of serological studies of548 sera samples of wild boars from 16 regions of Ukraine,collected during 2019 – 2020. The research was conductedon the basis of the State Scientific and Research Institute ofLaboratory Diagnostics and Veterinary and Sanitary Expertise(SSRILDVSE, Kyiv, Ukraine) by using the complementfixation test (CFT) and enzyme-linked immunosorbent assay(ELISA). In addition, all positive samples were further testedon yersiniosis with differential purposes.The systematization of obtained results show thatantibodies to Brucella spp. in sera samples from wild boarsin Ukraine were detected by CFT in 57 samples (10.4 % ofthe total number), by ELISA – in 83 (15.1 %). In general,antibodies to these pathogens were diagnosed in samplesfrom 13 regions (most often from Zhytomyr, Lviv andChernihiv).Positive samples by CFT and/or ELISA werefurther tested for the presence of antibodies to Yersiniaenterocolitica because, according to the literature andguidelines for diagnostic kits, possibility of crossreactions between brucellosis and yersiniosis. As a resultof differential studies, from the 83 positive on brucellosissamples, 42 also showed antibodies to Y. enterocolitica.Taking into account the cross-reactions between tests forbrucellosis and yersiniosis, antibodies to Brucella spp.during the analyzed period were found in 7.5 % of animals(in 41 of 548 samples).The prospect of this work is to further studies of theepizootic situation regarding brucellosis in the wild faunaof Ukraine. The obtained results indicate the circulationof antibodies to this zoonosis among wild boars in ourcountry.Key words: Brucella spp., Yersinia enterocolitica,zoonosis, serological studies, CFT, ELISA, wild fauna.
畜牧业成功发展的关键是国家的流行病福利。为了实施这套预防措施,需要一个完善的传染病诊断系统,包括布鲁氏菌病。尽管乌克兰被认为在农场动物中没有这种人畜共患疾病,但对我国野生动物中有关这种疾病的报道仍进行了充分的研究。本文介绍了2019年至2020年期间从乌克兰16个地区采集的548份野猪血清样本的血清学研究结果。本研究在乌克兰基辅国家劳动诊断兽医卫生专业科学研究院(SSRILDVSE)的基础上,采用补体固定试验(CFT)和酶联免疫吸附试验(ELISA)进行。此外,所有阳性样本都进行了进一步的yersinosis检测,以达到不同的目的。所得结果的系统化表明,CFT在57个样本(占总数的10.4%)和ELISA在83个样本(15.1%)中检测到乌克兰野猪血清样本中的布鲁氏菌属抗体。一般来说,在来自13个地区的样本中诊断出了针对这些病原体的抗体(最常见的是来自日托米尔、利沃夫和切尔尼戈夫)。通过CFT和/或ELISA检测阳性样本是否存在针对小肠结肠炎耶尔森菌的抗体,因为根据诊断试剂盒的文献和指南,布鲁氏菌病和耶尔森菌病之间可能存在交叉反应。作为差异研究的结果,在83例布鲁氏菌感染阳性病例中,42例也显示出小肠结肠炎杆菌抗体。考虑到布鲁氏菌病和耶尔西尼菌病检测之间的交叉反应,在分析期间,7.5%的动物(548个样本中的41个)中发现了布鲁氏菌属抗体。这项工作的前景是进一步研究乌克兰野生动物布鲁氏菌感染的情况。结果表明,这种人畜共患疾病的抗体在我国野猪中存在循环。关键词:布鲁氏菌属,小肠结肠炎耶尔森菌,人畜共患病,血清学研究,CFT,ELISA,野生动物。
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引用次数: 0
Efficacy of Actigen prebiotic drug preparation usage for growing meat indicators of productivity Actigen益生元制剂在生长肉生产指标中的应用效果
Pub Date : 2021-12-09 DOI: 10.33245/2310-4902-2021-168-2-37-48
A. Konopelko, V. Lyasota
To provide the population of Ukraine with livestock products should intensify research on the creation of highly effective tools and methods for diagnosis, prevention and treatmentof animals and poultry, as well as the use of biotechnologyand genetic engineering, develop an effective system of preventive, sanitary and zoohygienic measures to ensure veterinary welfare, environmental protection, obtaining high qualityproducts. Currently, they are looking for ways to increase theactivity of the natural resistance of animals and poultry withnatural and artificial immunomodulators, pro- and prebioticsand non-drug methods as an alternative to antibiotics.The aim of the study was to investigate the efficacy ofthe prebiotic drug Actigen in the rearing of dose-dependentmeat-producing turkeys.Zootechnical, zoohygienic, hematological and variational-statistical research methods were used to obtain scientificand practical data.The object of study were turkeys of the BIG-6 breed. Theprebiotic Actigen was added to the main diet (OR) of turkeysin the following doses: from the 1st to the 21st day: 0.4; 0.8and 1 g/kg of feed; from the 22nd to the 42nd day: 0.4; 0.6 and0.8 g/kg of feed; from the 42nd to the 120th day: 0.2; 0.4 and0.7 g/kg of feed. Mixing of prebiotic with compound feed wasperformed with a feed mixer on the farm for the productionof compound feed. The bird had free access to food and waterthroughout the fattening. ACTIGEN is a unique second-generation biologically active fraction derived from the outer wallof a specific yeast strain, Sacchamyces cerevisiae, selected byAlltech in the United States and designed to create a moreeffective product for optimizing farm and poultry health. Actigen is a form of yeast carbohydrate. Active substance: 1 kgcontains 280.0 g of crude protein. Pharmaceutical powderform.The results of experimental studies on the effectivenessof the prebiotic Actigen (manufacturer Alltech (U.K.) Limited/Alltech (YK) Limited, UK); which consists of mananoligosaccharides (MOS) isolated from the cell walls of the yeastSaccharomyces cerevisiae.The highest rates of preservation and growth of liveweight of broiler turkeys from the 1st to the 21st day of thepostnatal period of ontogenesis were obtained at a dose of Actigen 0.8 g/kg of feed, which was 3.99 % (P <0.05), obviouslythis is the optimal value.In the case of prebioticAktigen at a dose of 0.6 g / kg offeed, from the 22nd to the 42nd day of the postnatal period ofontogenesis, it was found that the rates of preservation andgrowth of live weight of broiler turkeys were 9.50% (P <0,05)- optimal dose.The use of the prebiotic Actigen from the 42nd to the120th day of the postnatal period of ontogenesis at a dose of0.4 g / kg of feed for broiler turkeys contributed to an increasein the preservation and increase in live weight by 15.31%(P <0.05) optimal value.The most positive effect of Actigen on the morphologicalparameters of poultry blood (hemoglobin content in one erythrocyte) was recor
为了向乌克兰人民提供畜产品,应加强对畜禽诊断,预防和治疗的高效工具和方法的研究,以及生物技术和基因工程的使用,制定有效的预防,卫生和动物卫生措施系统,以确保兽医福利,环境保护,获得高质量的产品。目前,他们正在寻找通过天然和人工免疫调节剂、益生元和益生元以及非药物方法来增加动物和家禽自然抗性活性的方法,作为抗生素的替代品。本研究的目的是研究益生元药物Actigen在饲养剂量依赖性肉鸡中的功效。采用动物技术、动物卫生学、血液学、变分统计学等研究方法,获取科学实用的数据。研究对象是BIG-6品种的火鸡。在火鸡主饲粮(OR)中按以下剂量添加益生元Actigen:第1 ~ 21天:0.4;0.8和1 g/kg饲料;第22 - 42天:0.4;0.6和0.8 g/kg饲料;第42 - 120天:0.2;0.4和0.7 g/kg饲料。在农场用饲料搅拌机将益生元与配合饲料进行混合,以生产配合饲料。在整个增肥过程中,这只鸟可以自由地获得食物和水。ACTIGEN是一种独特的第二代生物活性成分,提取自一种特定酵母菌(Sacchamyces cerevisiae)的外壁,由美国alltech公司选择,旨在创造一种更有效的产品,优化农场和家禽的健康。活性原是酵母碳水化合物的一种形式。活性物质:1公斤含粗蛋白质280.0 g。制药powderform。益生元Actigen(制造商Alltech(英国))有效性的实验研究结果Limited/Alltech (YK) Limited, UK);它由从酵母酵母细胞壁中分离出来的甘露寡糖(MOS)组成。肉仔鸡个体发育后第1 ~ 21天的活重保存率和生长率以0.8 g/kg饲料添加量最高,为3.99% (P <0.05),为最优值。在胚胎发育后第22 ~ 42天,以0.6 g / kg的剂量添加益生元akti原,肉仔鸡活重保存率和生长率为9.50% (P < 0.05)。在个体发育后第42 ~ 120天,在饲料中添加0.4 g / kg的益生元Actigen,可使肉仔鸡的保鲜率和活重提高15.31%(P <0.05)。Actigen对家禽血液形态学参数(单个红细胞血红蛋白含量)的影响以试验组2(使用浓度为0.8的肉鸡)最为显著;根据日龄的不同,分别添加0.6和0.4 g / kg饲料,使红细胞血红蛋白含量显著提高(21.0% ~ 25.0%)(P <0.05)。在生产条件下,建立了药物对生产力作用的卫生评价:增加火鸡的活重、平均日增重和鸡的安全性。关键词:工业化家禽养殖,养殖火鸡,饲养条件,安全,益生元,形态指标,代谢,生产力
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引用次数: 0
Species composition of circulation microflora and its resistance to antibacterial drugs in the conditions of the impulse veterinary clinic of the city of Lviv 利沃夫市脉冲兽医诊所循环菌群的种类组成及其对抗菌药物的耐药性
Pub Date : 2021-12-09 DOI: 10.33245/2310-4902-2021-168-2-65-71
Y. Kisera, L. Bozhyk, N. Grynevych, Y. Martyniv
Effective infection surveillance and control provides a safe environment for staff, clients and animals in the veterinary clinic. This reduces the risk of nosocomial and zoonotic infections. In addition, there is a significant risk of developing antimicrobial resistance, which is associated with both reasonable and inappropriate use of antibacterial drugs for the treatment of humans and animals, food production and the ineffectiveness of measures to control the spread of infectious diseases. Therefore, microbiological monitoring is important for the assessment of the microbial composition of the veterinary institution and the timely detection of its dynamic changes and the quality of sanitary and disinfection measures. Flushes from different surfaces were taken for research. The first stage – in the process of the clinic; the second – after disinfection. The results of bacteriological examinations of washes from the surfaces of the premises of the veterinary clinic "Impulse" in Lviv (examination, hospital and operating room) showed the presence in the samples of Escherichia coli and Staphylococcus spp. An important component of the clinic's laboratory in the infection control system is to determine the sensitivity of microorganisms in the room to antibiotics and systematic monitoring of general trends in antibiotic resistance, which will control the formation of stationary strains. The results showed that Escherichia coli is sensitive to erythromycin, cephalexin, chloramphenicol, ceftriaxone, gentamicin, doxacycline, ciprofloxacin, norfloxacin and methicillin and is resistant to kanamycin, clarithromycin and amoxiclav. At the same time Staphylococcus spp. were resistant to erythromycin, chloramphenicol, kanamycin, clarithromycin, amoxiclav and norfloxacin to all other drugs – sensitive.Key words: veterinary clinic, monitoring, infection control, prevention of stationary infections, resistance to antibiotics, disinfection.
有效的感染监测和控制为兽医诊所的工作人员、客户和动物提供了一个安全的环境。这降低了医院感染和人畜共患感染的风险。此外,还存在产生抗菌素耐药性的重大风险,这与在治疗人类和动物时合理和不适当地使用抗菌素药物、粮食生产以及控制传染病传播的措施无效有关。因此,微生物监测对于评估兽医机构的微生物组成,及时发现其动态变化和卫生消毒措施的质量具有重要意义。从不同的表面冲洗进行研究。第一阶段——在临床过程中;第二次-消毒后。对利沃夫“冲动”兽医诊所(检查、医院和手术室)场地表面的洗液进行细菌学检查的结果显示,在大肠杆菌和葡萄球菌的样本中存在。诊所实验室在感染控制系统中的一个重要组成部分是确定室内微生物对抗生素的敏感性,并系统监测抗生素耐药性的总体趋势。这将控制固定菌株的形成。结果表明,大肠杆菌对红霉素、头孢氨苄、氯霉素、头孢曲松、庆大霉素、多沙环素、环丙沙星、诺氟沙星和甲氧西林敏感,对卡那霉素、克拉霉素和阿莫昔洛夫耐药。同时,葡萄球菌对红霉素、氯霉素、卡那霉素、克拉霉素、阿莫昔拉和诺氟沙星均耐药,其余均敏感。关键词:兽医门诊,监测,感染控制,静止感染预防,抗生素耐药性,消毒。
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引用次数: 2
Modern aspects of contact dermatitis in industrial poultry farming 工业化家禽养殖中接触性皮炎的现代方面
Pub Date : 2021-12-09 DOI: 10.33245/2310-4902-2021-168-2-193-202
O. Yemelyanenko, M. Chornozub, A. Yemelyanenko, V. Koziy
Contact dermatitis is a lesion of the skin of broilers, which leads to a decrease in the quality of the carcass by 15-30 %. It is described as brown-black erosions and ulcers that occur on the breast (breast blisters, BB), hock burns (HB) and on the skin of the central pulp of the foot (food pad dermatitis, FPD). The most commonly affected is the pulp of the foot, followed by the hocks and chest. There are a number of factors that lead to crumb dermatitis. These include: the density of planting birds; type of troughs and the order of their use; feeding; the level of temperature and humidity in the room; type of litter, its quality and quantity; intestinal health. Birds are kept at a density of 8 individuals/m2 suffered less from dermatitis than those kept at a density of 13 individuals/m2 . Moreover, the harmful effects of high density were particularly pronounced at 18 individuals/m2 . The prevalence and severity of this pathology in broilers increases at later stages of fattening. Pododermatitis spread to several layers of skin. The condition of the crumbs worsened when the bird reached slaughter age with up to 64 % of the carcasses affected. In this case, lesions of the hocks and chest were rare. Wet litter (> 30 % moisture) is associated with an increase in the incidence and severity of contact dermatitis in broiler and turkey housing systems. This state of litter is most often registered in the winter-spring and autumn seasons. The quality of the litter, especially taking into account its humidity, has been identified as an important issue of well-being, which has a great negative impact on the condition of feathers, limb health and the frequency of contact dermatitis. Litter temperature is also important. With its growth, the degree of contact dermatitis increases. The reason for the increase in litter temperature is the increase in planting density and the accumulation of more manure, which enhances bacterial fermentation. With wet litter, bird feathers become wet or contaminated with litter, feces and dirt. It loses its protective properties. The level of bird welfare is declining sharply. Diagnosis of contact dermatitis in poultry is based on characteristic clinical signs. These are lameness, impaired mobility and discoloration of the skin, which often develops into an ulcer. The lesions are clearly separated from the intact tissue and often appear as ulcers surrounded by a deep hemorrhagic shaft. Contact dermatitis can develop in less than a week. Characteristic signs at the beginning of the disease are swelling, redness and increase in local temperature, thickening of the skin. Deep ulcers usually lead to abscesses in the underlying tissues and structures. Often the affected area is covered with crusts. If large ulcers develop, they can cause pain, slow growth, obstruct gait, and open bacteria to underlying tissues.Key words: broilers, contact dermatitis, dermatitis of the central pulp of the finger, dermatitis in the area of the hock
接触性皮炎是肉鸡皮肤的一种病变,可导致胴体质量下降15- 30%。它被描述为发生在乳房(乳房水疱,BB),跗关节烧伤(HB)和足部中央髓部皮肤(食物垫皮炎,FPD)的棕黑色糜烂和溃疡。最常受影响的是足髓,其次是飞节和胸部。导致碎屑性皮炎的因素有很多。这些指标包括:种鸟的密度;槽的类型及其使用顺序;喂养;室内的温度和湿度;凋落物的种类、质量和数量;肠道健康。8只/m2的密度比13只/m2的密度少患皮炎。在18只/m2时,高密度的有害影响尤为明显。这种病理在肉鸡的流行程度和严重程度在育肥后期增加。足部皮炎扩散到几层皮肤。当家禽达到屠宰年龄时,碎屑的状况恶化,高达64%的尸体受到影响。在这种情况下,飞节和胸部的病变是罕见的。在肉鸡和火鸡的饲养系统中,湿窝(湿度达到30%)与接触性皮炎的发病率和严重程度增加有关。这种凋落物状态最常发生在冬春秋季。垃圾的质量,特别是考虑到它的湿度,已经被确定为一个重要的健康问题,这对羽毛的状况,肢体健康和接触性皮炎的频率有很大的负面影响。凋落物的温度也很重要。随着它的生长,接触性皮炎的程度也在增加。凋落物温度升高的原因是种植密度增加,粪便积累增多,细菌发酵增强。有了湿的垃圾,鸟的羽毛变湿或被垃圾、粪便和污垢污染。它失去了保护作用。鸟类福利水平急剧下降。家禽接触性皮炎的诊断是基于典型的临床症状。这些症状包括跛行、活动能力受损和皮肤变色,通常会发展成溃疡。病变与完整组织明显分离,常表现为溃疡,周围有深出血轴。接触性皮炎可以在不到一周的时间内发展。疾病开始时的特征体征是皮肤肿胀,发红,局部温度升高,皮肤增厚。深度溃疡通常会导致底层组织和结构的脓肿。受影响的区域通常被硬壳覆盖。如果形成大溃疡,它们会引起疼痛,生长缓慢,妨碍步态,并使细菌进入底层组织。关键词:肉鸡,接触性皮炎,指中枢髓皮炎,飞节区皮炎,胸部皮炎
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引用次数: 0
Climatic stress in pregnant sows: adaptive responses and effects on productivity 妊娠母猪的气候胁迫:适应性反应和对生产力的影响
Pub Date : 2021-12-09 DOI: 10.33245/2310-4902-2021-168-2-147-157
O. Poroshinska, S. Shmayun, L. Stovbetska, A. Yemelyanenko, N. Nishemenko, V. Koziy
The article presents data from the scientific literaturedescribing the influence of microclimate parameters on thebody of sows and their offspring. The key factors of thenormal course of physiological processes in the body of sowsand piglets are the optimal temperature, light, air velocity andhumidity. Sensitivity of sows to climatic factors increasessignificantly during pregnancy and lactation. At elevatedoutdoor temperatures, heat stress develops, which negativelyaffects well-being and productivity of sows and significantlyharms the offspring due to intrauterine temperature load. Itis established that there are differences in genetic tolerance to high temperature between different breeds of sows.Changes in physiological and behavioral parameters can beobserved at different stages of the reproductive cycle of sows.Pregnant sows respond to heat stress by increasing rectal andskin temperature, respiration rate and reducing their overallactivity. Elevated ambient temperature during late pregnancyincreases the catabolism of lipids and proteins in the bodyof sows, the concentration of adrenocorticotropic hormone,cortisol in the blood increases. Heat-exposed sows also havea shorter gestation period and a lower nest weight of pigletsat birth. During lactation, there are changes in general andfeed behavior, reduced feed intake and as a result, the processof milk production is disrupted. In particular, it was foundthat with increasing temperature from 20.0 to 29.0 °C milkproduction in sows decreases from 10.43 to 7.35 kg/day(p <0.05). The content of immunoglobulins, vitamins andmicroelements in milk decreases. This leads to a violation ofimportant physiological functions of the body of piglets andhas a negative impact on their growth and development. Themost critical periods for sows are the end of summer and thebeginning of autumn, when anestrus is observed, the rates offertilization, farrowing, fertility and weight gain of piglets arereduced. This is due to an imbalance in the hypothalamicpituitary-adrenal system and high levels of melatonin in theblood. The use of physiological and behavioral indicatorsis necessary to prevent climatic stress and increase animalproductivity.Key words: physiology, pigs, stress factors, thermoregulation, behavior, reproductive system, pregnancy, lactation.
本文介绍了来自科学文献的数据,描述了小气候参数对母猪及其后代身体的影响。母猪和仔猪生理过程正常进行的关键因素是适宜的温度、光照、风速和湿度。母猪对气候因素的敏感性在妊娠期和哺乳期显著增加。在室外温度升高的情况下,会产生热应激,这对母猪的健康和生产力产生负面影响,并且由于宫内温度负荷会严重损害后代。已确定不同品种母猪对高温的遗传耐受性存在差异。在母猪繁殖周期的不同阶段,可以观察到生理和行为参数的变化。怀孕母猪对热应激的反应是增加直肠和皮肤温度、呼吸速率和减少整体活动。妊娠后期环境温度升高,母猪体内脂质和蛋白质的分解代谢增加,血液中促肾上腺皮质激素(皮质醇)的浓度增加。热暴露母猪的妊娠期也较短,仔猪出生时窝重较低。在哺乳期间,一般和饲料行为发生变化,采食量减少,因此,产奶过程被打乱。随着温度从20.0℃升高至29.0℃,母猪产奶量从10.43 kg/d下降至7.35 kg/d (p <0.05)。牛奶中的免疫球蛋白、维生素和微量元素含量降低。这导致仔猪身体的重要生理功能受到侵犯,并对其生长发育产生负面影响。母猪最关键的时期是夏末秋初,此时出现发情,仔猪受精率、产仔率、产仔率和增重率下降。这是由于下丘脑-垂体-肾上腺系统失衡以及血液中褪黑激素水平过高造成的。使用生理和行为指标是防止气候压力和提高动物生产力所必需的。关键词:生理学,猪,应激因素,体温调节,行为,生殖系统,妊娠,哺乳
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Naukovii visnik veterinarnoyi meditsini
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