Pub Date : 1900-01-01DOI: 10.31549/2541-8289-2022-6-4-55-60
S. P. Zhelezny, P. Zhelezny, Yu.K. Zheleznaya, E.V. Zubrilin
The results of long-term clinical observations on the prosthetics of denture defects using dental implants in patients after osteoplastic surgeries performed for inflammatory diseases, traumatic lesions, tumors and tumor-like formations of the maxillofacial region in 246 patients are presented. Free-end edentulous spaces were identified in 174 patients, bounded edentulous spaces – in 72. Two types of dental implants were used: porous titanium nickelide and screw. In 99 patients, dental implants were transplanted together with a bone allo- or autograft during bone grafting of a jaw defect, in 60 patients – in bone regenerate in the long term after bone grafting and replacement of the defect with a neoformed bone, in 87 patients – in sinus lifting. During orthopedic treatment, 359 fixed prostheses and 18 removable structures based on dental implants were made. The results of ostseointegration of dental implants were evaluated by comparative osteodensiometry within 1.5 to 12 months. Clinical observations and osteodensiometry have shown that the integration process evolves more fully and effectively around titanium nickelide implants with permeable porosity. The most common complication of dental implantation in bone regenerate is peri-implantitis, which developed in 30 patients (5.18%). Positive aesthetic and functional long-term results of denture defects prosthetics defects on implants in terms of up to 12 years were observed in 90.8% of cases
{"title":"DENTAL IMPLANTATION IN PROSTHETICS OF PATIENTS AFTER OSTEORECONSTRUCTIVE PLASTY","authors":"S. P. Zhelezny, P. Zhelezny, Yu.K. Zheleznaya, E.V. Zubrilin","doi":"10.31549/2541-8289-2022-6-4-55-60","DOIUrl":"https://doi.org/10.31549/2541-8289-2022-6-4-55-60","url":null,"abstract":"The results of long-term clinical observations on the prosthetics of denture defects using dental implants in patients after osteoplastic surgeries performed for inflammatory diseases, traumatic lesions, tumors and tumor-like formations of the maxillofacial region in 246 patients are presented. Free-end edentulous spaces were identified in 174 patients, bounded edentulous spaces – in 72. Two types of dental implants were used: porous titanium nickelide and screw. In 99 patients, dental implants were transplanted together with a bone allo- or autograft during bone grafting of a jaw defect, in 60 patients – in bone regenerate in the long term after bone grafting and replacement of the defect with a neoformed bone, in 87 patients – in sinus lifting. During orthopedic treatment, 359 fixed prostheses and 18 removable structures based on dental implants were made. The results of ostseointegration of dental implants were evaluated by comparative osteodensiometry within 1.5 to 12 months. Clinical observations and osteodensiometry have shown that the integration process evolves more fully and effectively around titanium nickelide implants with permeable porosity. The most common complication of dental implantation in bone regenerate is peri-implantitis, which developed in 30 patients (5.18%). Positive aesthetic and functional long-term results of denture defects prosthetics defects on implants in terms of up to 12 years were observed in 90.8% of cases","PeriodicalId":342613,"journal":{"name":"Sibirskij medicinskij vestnik","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134178308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.31549/2541-8289-2021-2-15-18
Е.А. Drobyazgin, Y. Chikinev, V. F. Khusainov, K. I. Shcherbina, Е.S. Khusainova
The article analyzes the quality of life of 28 patients with bullous pulmonary emphysema, operated on from the dual-port approach at the State Novosibirsk Regional Clinical Hospital over the period from 2017 to 2020. The assessment was performed using the SF-36 nonspecific questionnaire and the San Diego University Shortness of Breath Questionnaire (UCSD-SOBQ). The study revealed a significant improvement in the quality of life of patients operated on from a redual-port approach.
{"title":"THE QUALITY OF LIFE ASSESSMENT IN PATIENTS AFTER DUAL-PORT VIDEOTHORACOSCOPIC SURGERY FOR BULLOUS PULMONARY EMPHYSEMA","authors":"Е.А. Drobyazgin, Y. Chikinev, V. F. Khusainov, K. I. Shcherbina, Е.S. Khusainova","doi":"10.31549/2541-8289-2021-2-15-18","DOIUrl":"https://doi.org/10.31549/2541-8289-2021-2-15-18","url":null,"abstract":"The article analyzes the quality of life of 28 patients with bullous pulmonary emphysema, operated on from the dual-port approach at the State Novosibirsk Regional Clinical Hospital over the period from 2017 to 2020. The assessment was performed using the SF-36 nonspecific questionnaire and the San Diego University Shortness of Breath Questionnaire (UCSD-SOBQ). The study revealed a significant improvement in the quality of life of patients operated on from a redual-port approach.","PeriodicalId":342613,"journal":{"name":"Sibirskij medicinskij vestnik","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126025889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.31549/2541-8289-2023-7-2-54-59
I. Klimova, A. Ovchinnikov, A. Funtikov, N.G. Timinskaya, Y.A. Tatarenko, R.M. Zakrevskaya
Researches on respiratory viral infections has established an association between infection and risk of suicide. Several reports informed on the impact of the COVID-19 pandemic on adolescent mental health, manifesting as depression and anxiety, suicide and self-harm. In particular, mood disorders are associated with the presence of antibodies against influenza A and B viruses and the coronavirus strain (HCov-NL63). We retrospectively examined 113 adolescents who had COVID-19 at the age of 11 to 14 years (78 girls, 35 boys), mean age 12 ± 2 years, who had a history of suicidal behavior. All adolescents noted on average after 3–4 months after they have suffered COVID-19, an increase in despondency with the gradual addition of apathy, unwillingness to do anything; a significant decrease or complete lack of motivation for any type of activity was revealed. Within 6 months after the infection, suicidal thoughts and tendencies arose. These circumstances require further study in order to develop effective methods of treatment and rehabilitation measures.
{"title":"SUICIDAL BEHAVIOR OF ADOLESCENTS DURING THE NOVEL CORONAVIRUS INFECTION PANDEMIC","authors":"I. Klimova, A. Ovchinnikov, A. Funtikov, N.G. Timinskaya, Y.A. Tatarenko, R.M. Zakrevskaya","doi":"10.31549/2541-8289-2023-7-2-54-59","DOIUrl":"https://doi.org/10.31549/2541-8289-2023-7-2-54-59","url":null,"abstract":"Researches on respiratory viral infections has established an association between infection and risk of suicide. Several reports informed on the impact of the COVID-19 pandemic on adolescent mental health, manifesting as depression and anxiety, suicide and self-harm. In particular, mood disorders are associated with the presence of antibodies against influenza A and B viruses and the coronavirus strain (HCov-NL63). We retrospectively examined 113 adolescents who had COVID-19 at the age of 11 to 14 years (78 girls, 35 boys), mean age 12 ± 2 years, who had a history of suicidal behavior. All adolescents noted on average after 3–4 months after they have suffered COVID-19, an increase in despondency with the gradual addition of apathy, unwillingness to do anything; a significant decrease or complete lack of motivation for any type of activity was revealed. Within 6 months after the infection, suicidal thoughts and tendencies arose. These circumstances require further study in order to develop effective methods of treatment and rehabilitation measures.","PeriodicalId":342613,"journal":{"name":"Sibirskij medicinskij vestnik","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132767742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.31549/2541-8289-2022-6-4-36-42
Eran Vaknin, R. L. Lobastov, A. Ovchinnikov, I. Klimova, I.A. Gobernik, A. M. Karpushkin
The article describes certain aspects of negative psychosocial influence as a complex of specific exogenous-endogenous factors involved in the development of the schizophrenic process. For example, this is the lack of communicative-emotional parent-child relationships, in which one's own existential experience is not formed, which is necessary for the formation of value-motivational behavioral potential. As a result, there is an inability to self-reflection and internal self-regulation, which provoke, among other things, the mechanisms of alienation of the inner I. The issues of metacognitive potential deficits in persons suffering from schizophrenia (social cognition) are also touched upon.
{"title":"FEATURES OF PSYCHODYNAMIC DISORDERS IN THE STRUCTURE OF SCHIZOPHRENIC DISORDER (DEFICIENCY OF INTRA-PSYCHIC LIFE, COMMUNICATIVE-EMOTIONAL RELATIONSHIPS)","authors":"Eran Vaknin, R. L. Lobastov, A. Ovchinnikov, I. Klimova, I.A. Gobernik, A. M. Karpushkin","doi":"10.31549/2541-8289-2022-6-4-36-42","DOIUrl":"https://doi.org/10.31549/2541-8289-2022-6-4-36-42","url":null,"abstract":"The article describes certain aspects of negative psychosocial influence as a complex of specific exogenous-endogenous factors involved in the development of the schizophrenic process. For example, this is the lack of communicative-emotional parent-child relationships, in which one's own existential experience is not formed, which is necessary for the formation of value-motivational behavioral potential. As a result, there is an inability to self-reflection and internal self-regulation, which provoke, among other things, the mechanisms of alienation of the inner I. The issues of metacognitive potential deficits in persons suffering from schizophrenia (social cognition) are also touched upon.","PeriodicalId":342613,"journal":{"name":"Sibirskij medicinskij vestnik","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114216227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.31549/2541-8289-2021-3-10-18
А.N. Ageev, A. Dergilev, V. Obodov, А.V. Obodov
{"title":"COMPARATIVE DIAGNOSTIC VALUE OF VIRTUAL ENDOSCOPY AND TEXT DESCRIPTIONS OF COMPUTER TOMOGRAPHY OF THE LACRIMAL PASSAGES IN PLANNING AND IMPLEMENTATION OF ENDONASAL ENDOSCOPIC DACRYOCYSTORHINOSTOMY","authors":"А.N. Ageev, A. Dergilev, V. Obodov, А.V. Obodov","doi":"10.31549/2541-8289-2021-3-10-18","DOIUrl":"https://doi.org/10.31549/2541-8289-2021-3-10-18","url":null,"abstract":"","PeriodicalId":342613,"journal":{"name":"Sibirskij medicinskij vestnik","volume":"409 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132495024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.31549/2541-8289-2021-1-34-39
P. Pilipenko, V. Voytsitsky, Y. Dobresko
Chemotherapy-induced peripheral neuropathy (CIPN) is a progressive, long-lasting and often irreversible condition characterized by pain, numbness, tingling, and sensitization to cold in the hands and feet that affects 30 to 40% of patients undergoing chemotherapy. This leads to disability and a deterioration in the quality of life of patients against the background of the absence of tumor progression, representing a serious side effect of treatment. There are certain clinical risk factors for CIPN, but none of them accurately indicates the severity and possibility of developing the disease in oncologic patients. Prediction, early detection and monitoring of side effects of chemotherapy is of great importance in the treatment of cancer patients. Further research in this field will make it possible to correctly and effectively plan and carry out treatment and rehabilitation arrangements using preventive technologies.
{"title":"PROBLEMS OF EARLY DIAGNOSIS OF CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY","authors":"P. Pilipenko, V. Voytsitsky, Y. Dobresko","doi":"10.31549/2541-8289-2021-1-34-39","DOIUrl":"https://doi.org/10.31549/2541-8289-2021-1-34-39","url":null,"abstract":"Chemotherapy-induced peripheral neuropathy (CIPN) is a progressive, long-lasting and often irreversible condition characterized by pain, numbness, tingling, and sensitization to cold in the hands and feet that affects 30 to 40% of patients undergoing chemotherapy. This leads to disability and a deterioration in the quality of life of patients against the background of the absence of tumor progression, representing a serious side effect of treatment. There are certain clinical risk factors for CIPN, but none of them accurately indicates the severity and possibility of developing the disease in oncologic patients. Prediction, early detection and monitoring of side effects of chemotherapy is of great importance in the treatment of cancer patients. Further research in this field will make it possible to correctly and effectively plan and carry out treatment and rehabilitation arrangements using preventive technologies.","PeriodicalId":342613,"journal":{"name":"Sibirskij medicinskij vestnik","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129698170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.31549/2541-8289-2021-3-24-31
S. N. Volchenko, A. Dergilev, P. Sysolyatin, Yu V Tsayukov, N. Gorbunov, A. Sudarkina, K.A. Nizovtsev
{"title":"MSCT-DIAGNOSTICS OF ACUTE INJURY OF THE MAXILLOFACIAL AREA IN A GENERAL MULTIDISCIPLINARY HOSPITAL","authors":"S. N. Volchenko, A. Dergilev, P. Sysolyatin, Yu V Tsayukov, N. Gorbunov, A. Sudarkina, K.A. Nizovtsev","doi":"10.31549/2541-8289-2021-3-24-31","DOIUrl":"https://doi.org/10.31549/2541-8289-2021-3-24-31","url":null,"abstract":"","PeriodicalId":342613,"journal":{"name":"Sibirskij medicinskij vestnik","volume":"91 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131192718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.31549/2541-8289-2022-6-4-4-12
A. Tereshchenko, D. Nepomnyashchikh, O. N. Miller, O. Postnikova, Y. Ovechkina, E. E. Abramova, E. Vinogradova
The use of overdrive transesophageal cardiac pacing (OTECP) in atrial flutter (AF) can reduce the number of external electrical cardioversion (EEC) in arrhythmia refractory to drug-induced cardioversion. The conversion of AF to atrial fibrillation (AFib) with subsequent spontaneous sinus rhythm (SR) restoration with the help of OTECP and accompanying antiarrhythmic therapy (AAT) was carried out in 59 patients with diseases of the cardiovascular system aged 40 to 77 years. The duration of AF before pacing was 35.93 ± 5.25 days. The efficiency of OTECP was 71.19%, and the time for spontaneous SR restoration was on average 16.92 ± 2.67 h. During pacing, the combined AAT has no advantages over monotherapy, despite its higher efficiency before OTECP. The obtained results indicate that the duration of AF prior to the OTECP procedure did not affect either the effectiveness of the procedure or the timing of spontaneous SR restoration. Inadequate control of blood pressure during treatment was a risk factor for reducing the effectiveness of OTECP, and contributed to the persistence or recurrence of arrhythmia. In patients with AF without AH, a decrease in left ventricular contractility and severe grade of CHF with an increase in left ventricular chamber dimension at end systole, a decrease in ejection fraction (EF) and fractional shortening (FS), reduces the likelihood of spontaneous SR restoration after OTECP, while additional administration of digoxin to increase myocardial contractility did not influence the effectiveness the therapy being carried out. The enlarged dimensions of the left atrium, which did not go beyond the critical dimensions, also had no influence on the effectiveness of the therapy. The efficiency of SR restoration against the background of AAT was 71.19%. Taking into account the EEC accompanied by the treatment performed corresponds to 83.05%. The effectiveness of OTECP when performed on the background of mono- or combined AAT did not differ significantly and amounted to 70.83 and 71.43%, as well as the terms of spontaneous SR restoration — 16.94 ± 2.86 and 16.89 ± 2, 48 hours respectively. The effectiveness of OTECP during mono- or combined AAT was 70.83% and 71.43%, respectively, and the time for spontaneous SR restoration was 16.94 ± 2.86 and 16.89 ± 2.48 hours. Medicamentous cardioversion of AF prior to the OTECP procedure is effective in 54.29% of cases and only with the combined AAT.
{"title":"INFLUENCE OF ARTERIAL HYPERTENSION AND CHRONIC HEART FAILURE ON THE EFFECTIVENESS OF SINUS RHYTHM RESTORATION IN PATIENTS WITH ATRIAL FLUTTER","authors":"A. Tereshchenko, D. Nepomnyashchikh, O. N. Miller, O. Postnikova, Y. Ovechkina, E. E. Abramova, E. Vinogradova","doi":"10.31549/2541-8289-2022-6-4-4-12","DOIUrl":"https://doi.org/10.31549/2541-8289-2022-6-4-4-12","url":null,"abstract":"The use of overdrive transesophageal cardiac pacing (OTECP) in atrial flutter (AF) can reduce the number of external electrical cardioversion (EEC) in arrhythmia refractory to drug-induced cardioversion. The conversion of AF to atrial fibrillation (AFib) with subsequent spontaneous sinus rhythm (SR) restoration with the help of OTECP and accompanying antiarrhythmic therapy (AAT) was carried out in 59 patients with diseases of the cardiovascular system aged 40 to 77 years. The duration of AF before pacing was 35.93 ± 5.25 days. The efficiency of OTECP was 71.19%, and the time for spontaneous SR restoration was on average 16.92 ± 2.67 h. During pacing, the combined AAT has no advantages over monotherapy, despite its higher efficiency before OTECP. The obtained results indicate that the duration of AF prior to the OTECP procedure did not affect either the effectiveness of the procedure or the timing of spontaneous SR restoration. Inadequate control of blood pressure during treatment was a risk factor for reducing the effectiveness of OTECP, and contributed to the persistence or recurrence of arrhythmia. In patients with AF without AH, a decrease in left ventricular contractility and severe grade of CHF with an increase in left ventricular chamber dimension at end systole, a decrease in ejection fraction (EF) and fractional shortening (FS), reduces the likelihood of spontaneous SR restoration after OTECP, while additional administration of digoxin to increase myocardial contractility did not influence the effectiveness the therapy being carried out. The enlarged dimensions of the left atrium, which did not go beyond the critical dimensions, also had no influence on the effectiveness of the therapy. The efficiency of SR restoration against the background of AAT was 71.19%. Taking into account the EEC accompanied by the treatment performed corresponds to 83.05%. The effectiveness of OTECP when performed on the background of mono- or combined AAT did not differ significantly and amounted to 70.83 and 71.43%, as well as the terms of spontaneous SR restoration — 16.94 ± 2.86 and 16.89 ± 2, 48 hours respectively. The effectiveness of OTECP during mono- or combined AAT was 70.83% and 71.43%, respectively, and the time for spontaneous SR restoration was 16.94 ± 2.86 and 16.89 ± 2.48 hours. Medicamentous cardioversion of AF prior to the OTECP procedure is effective in 54.29% of cases and only with the combined AAT.","PeriodicalId":342613,"journal":{"name":"Sibirskij medicinskij vestnik","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116916792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.31549/2541-8289-2023-7-2-4-11
T. Belousova, I. V. Andryushina, A. Novoseltseva, O. L. Bykadorova, A. Lebedeva
Introduction. The provision of medical care to children born with very low body weight (VLBW) and extremely low body weight (ELBW) belongs to the category of tertiary level neonatal intensive care (TINC) and reflects the effectiveness of regional obstetric-gynecological, neonatology and pediatric services; and the study of the structure of morbidity and outcomes in this category of newborn babies determines methodological, organizational and medical problems of the territory. The aim of the study. To assess the structure of morbidity and outcomes in premature newborns with ELBW and VLBW at birth in the setting of a Regional Perinatal Center during one year follow-up. Materials and methods. As part of the study, a retrospective analysis of 132 inpatient medical records of infants born preterm with VLBW and ELBW in the Regional Perinatal Center of the Novosibirsk State Regional Clinical Hospital in 2022 was performed. Patients were divided into two groups. Group 1 included 80 babies born with VLBW (birth weight 1000–1499 g), group 2 included 52 babies with ELBW at birth (less than 1000 g). Results. These children with VLBW and ELBW at birth are heterogeneous in the structure of prematurity, which is due to the presence of intrauterine growth retardation (IUGR) in some of them. At the same time, only the group of children born with VLBW is heterogeneous: 77.5% were registered as extremely premature, of which 63.7% were very preterm, and 13.7% were moderately preterm and 8.8% were late preterm. The category of extremely preterm prevailed among children with ELBW – 71,2%. 28% of children born prematurely had IUGR. Its structure was also heterogeneous: among children with VLBW at birth, there were equally wasty for gestational age (GA) – 15% and small for GA – 13.8%. Among children with ELBW, the small for GA – 21.1% dominated, against 5.8% – light for GA. Operative delivery (cesarean section) was chosen as the predominant method in both groups – 77.5 and 78.8% of cases, respectively. Diseases associated with prematurity were more often registered among children with ELBW at birth: severe asphyxia at birth (34.6%) vs VLBW (5%), p < 0.001; HS PDA (38.5%) vs VLBW (17.5%), p < 0.01; IVH III deg. (13.5%) vs VLBW (1.3%), p < 0.01; RP = retinopathy (32.7%) vs VLBW (8.8%), p < 0.001; severe form of BPD (23.8%) vs VLBW (5.6%), p < 0.05; NEC II-III stages (17.3%) vs ONMT (5%), p < 0.05; neonatal sepsis (34.6%) vs VLBW (12.5%), p < 0.01. The duration of inpatient treatment is 2 times higher in children with ELBW at birth: 92 ± 6.4 vs 48.8 ± 2 bed/patient days In the structure of morbidity, there were no differences in grade II IVH, PVL, mild and moderate BPD and Congenital Disorder (p > 0.05). Children with ELBW needed more treatment at birth: treatment of RP required intravitreal administration of ranibizumab (53%) vs VLBW (28.6%); surgical treatment of NEC stage III was carried out only in children with ELBW; the duration of respiratory support, regardless of
介绍。向出生时体重极低和体重极低的儿童提供医疗护理属于三级新生儿重症监护范畴，反映了地区妇产科、新生儿和儿科服务的有效性;对这类新生儿的发病率结构和结果的研究决定了该领土的方法、组织和医疗问题。研究的目的。目的:通过一年的随访，评估在地区围产期中心环境下出生的ELBW和VLBW早产儿的发病率结构和结局。材料和方法。作为研究的一部分，回顾性分析了2022年新西伯利亚州地区临床医院区域围产期中心132例患有VLBW和ELBW的早产婴儿的住院病历。患者分为两组。组1包括80例出生时体重过低(出生体重1000 - 1499 g)的婴儿，组2包括52例出生时体重过低(小于1000 g)的婴儿。这些出生时患有VLBW和ELBW的儿童在早产结构上是异质的，这是由于其中一些儿童存在宫内生长迟缓(IUGR)。与此同时，只有VLBW患儿组具有异质性:77.5%为极度早产儿，其中63.7%为非常早产儿，13.7%为中度早产儿，8.8%为晚期早产儿。极端早产类别在ELBW患儿中占比为71.2%。28%的早产儿童患有IUGR。其结构也具有异质性:在出生时患有VLBW的儿童中，同样存在胎龄(GA)的浪费(15%)和胎龄小(13.8%)。在ELBW患儿中，小遗传型占21.1%，轻遗传型占5.8%。两组均以手术分娩(剖宫产)为主，分别占77.5%和78.8%。与早产相关的疾病在出生时患有ELBW的儿童中更常见:出生时严重窒息(34.6%)vs VLBW (5%)， p < 0.001;HS PDA (38.5%) vs VLBW (17.5%)， p < 0.01;IVH III度(13.5%)vs VLBW (1.3%)， p < 0.01;RP =视网膜病变(32.7%)vs VLBW (8.8%)， p < 0.001;重度BPD (23.8%) vs VLBW (5.6%)， p < 0.05;NEC II-III期(17.3%)vs ONMT (5%)， p < 0.05;新生儿脓毒症(34.6%)vs VLBW (12.5%)， p < 0.01。出生时ELBW患儿住院时间为(92±6.4)比(48.8±2)张/患者d，是出生时ELBW患儿住院时间的2倍。在发病结构上，II级IVH、PVL、轻中度BPD和先天性疾病无差异(p < 0.05)。ELBW患儿在出生时需要更多的治疗:RP的治疗需要玻璃体内给药雷尼单抗(53%)，而VLBW (28.6%);NEC III期手术治疗仅在ELBW患儿中进行;无论采用何种方法，ELBW患儿的呼吸支持时间更长，分别为686.9±130.3小时和156.3±26小时。所有出生时患有ONMT和ENMT的早产儿死亡率为13.6%，而大多数出生时极度早产的ELBW儿童组的死亡率高出5倍。在病分学方面，所有ELBW和VLBW患儿的主要死亡原因是新生儿脓毒症——在50%的病例中，出生时ELBW患儿(38.8%)的死亡率是VLBW患儿(20%)的1.9倍，p < 0.05。结论。本文的分析表明，在区域围产期中心的环境中，患有VLBW和ELBW的早产儿在早产结构上是一个相当异质性的群体，这除其他外，影响了极端负面结果(致命)和发病率结构的形成，在不同阶段向他们提供的护理数量，其综合性和专业化，以及住院治疗的时间。综上所述，我们可以得出结论，在所有患有超低体重和超低体重的早产儿中，最困难、经济成本最高、预后最差的是极早产新生儿。
{"title":"THE STRUCTURE OF MORBIDITY AND OUTCOMES IN NEWBORNS WITH VERY LOW AND EXTREMELY LOW BODY WEIGHT IN THE REGIONAL PERINATAL CENTER","authors":"T. Belousova, I. V. Andryushina, A. Novoseltseva, O. L. Bykadorova, A. Lebedeva","doi":"10.31549/2541-8289-2023-7-2-4-11","DOIUrl":"https://doi.org/10.31549/2541-8289-2023-7-2-4-11","url":null,"abstract":"Introduction. The provision of medical care to children born with very low body weight (VLBW) and extremely low body weight (ELBW) belongs to the category of tertiary level neonatal intensive care (TINC) and reflects the effectiveness of regional obstetric-gynecological, neonatology and pediatric services; and the study of the structure of morbidity and outcomes in this category of newborn babies determines methodological, organizational and medical problems of the territory. The aim of the study. To assess the structure of morbidity and outcomes in premature newborns with ELBW and VLBW at birth in the setting of a Regional Perinatal Center during one year follow-up. Materials and methods. As part of the study, a retrospective analysis of 132 inpatient medical records of infants born preterm with VLBW and ELBW in the Regional Perinatal Center of the Novosibirsk State Regional Clinical Hospital in 2022 was performed. Patients were divided into two groups. Group 1 included 80 babies born with VLBW (birth weight 1000–1499 g), group 2 included 52 babies with ELBW at birth (less than 1000 g). Results. These children with VLBW and ELBW at birth are heterogeneous in the structure of prematurity, which is due to the presence of intrauterine growth retardation (IUGR) in some of them. At the same time, only the group of children born with VLBW is heterogeneous: 77.5% were registered as extremely premature, of which 63.7% were very preterm, and 13.7% were moderately preterm and 8.8% were late preterm. The category of extremely preterm prevailed among children with ELBW – 71,2%. 28% of children born prematurely had IUGR. Its structure was also heterogeneous: among children with VLBW at birth, there were equally wasty for gestational age (GA) – 15% and small for GA – 13.8%. Among children with ELBW, the small for GA – 21.1% dominated, against 5.8% – light for GA. Operative delivery (cesarean section) was chosen as the predominant method in both groups – 77.5 and 78.8% of cases, respectively. Diseases associated with prematurity were more often registered among children with ELBW at birth: severe asphyxia at birth (34.6%) vs VLBW (5%), p < 0.001; HS PDA (38.5%) vs VLBW (17.5%), p < 0.01; IVH III deg. (13.5%) vs VLBW (1.3%), p < 0.01; RP = retinopathy (32.7%) vs VLBW (8.8%), p < 0.001; severe form of BPD (23.8%) vs VLBW (5.6%), p < 0.05; NEC II-III stages (17.3%) vs ONMT (5%), p < 0.05; neonatal sepsis (34.6%) vs VLBW (12.5%), p < 0.01. The duration of inpatient treatment is 2 times higher in children with ELBW at birth: 92 ± 6.4 vs 48.8 ± 2 bed/patient days In the structure of morbidity, there were no differences in grade II IVH, PVL, mild and moderate BPD and Congenital Disorder (p > 0.05). Children with ELBW needed more treatment at birth: treatment of RP required intravitreal administration of ranibizumab (53%) vs VLBW (28.6%); surgical treatment of NEC stage III was carried out only in children with ELBW; the duration of respiratory support, regardless of ","PeriodicalId":342613,"journal":{"name":"Sibirskij medicinskij vestnik","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128013472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：