Pub Date : 2009-12-11DOI: 10.1109/MHS.2009.5351907
H. Kurita, T. Takata, H. Yasuda, K. Takashima, A. Mizuno
The advantage of single-molecule experiments on analysis of DNA-protein interactions is that it can manipulate the physical form of individual DNA molecules. In these experiments, surface treatments for anchoring individual DNA molecules are important. In this study, we carried out fluorescent observations of individual DNA molecules on phospholipid bilayers. First, we constructed a PDMS microchannel and neutravidin was immobilized on the glass surface to tether individual DNA molecules. And then, DOPC liposomes were applied to the microchannel and the lipid bilayers were constructed. Biotinylated DNA molecules labeled with fluorescent dyes were then injected to the channel and they were tethered to the glass surface. As a result, we obtained clear images of the DNA molecules. Intriguingly, in addition, we found that if the fluorescent observation was carried out with the phospholipid bilayers, photobleaching of the fluorescently-labeled DNA was slower by comparison with that without the bilayers. Moreover, we applied this method to DNA-protein interactions at a single-molecule level.
{"title":"Fluorescent observation of individual DNA molecules on phospholipid bilayers and its application to analysis of DNA-protein interactions","authors":"H. Kurita, T. Takata, H. Yasuda, K. Takashima, A. Mizuno","doi":"10.1109/MHS.2009.5351907","DOIUrl":"https://doi.org/10.1109/MHS.2009.5351907","url":null,"abstract":"The advantage of single-molecule experiments on analysis of DNA-protein interactions is that it can manipulate the physical form of individual DNA molecules. In these experiments, surface treatments for anchoring individual DNA molecules are important. In this study, we carried out fluorescent observations of individual DNA molecules on phospholipid bilayers. First, we constructed a PDMS microchannel and neutravidin was immobilized on the glass surface to tether individual DNA molecules. And then, DOPC liposomes were applied to the microchannel and the lipid bilayers were constructed. Biotinylated DNA molecules labeled with fluorescent dyes were then injected to the channel and they were tethered to the glass surface. As a result, we obtained clear images of the DNA molecules. Intriguingly, in addition, we found that if the fluorescent observation was carried out with the phospholipid bilayers, photobleaching of the fluorescently-labeled DNA was slower by comparison with that without the bilayers. Moreover, we applied this method to DNA-protein interactions at a single-molecule level.","PeriodicalId":344667,"journal":{"name":"2009 International Symposium on Micro-NanoMechatronics and Human Science","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121365940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-12-11DOI: 10.1109/MHS.2009.5351741
E. Vela, M. Hafez, S. Régnier, S. Bouchigny
In this work, we present the non-contact manipulation of mesoscale random-shaped, large and heavy objects immersed in thin liquid water (< 0.8 mm). The manipulation principle used is the modulation of surface tension by infra red (IR) laser (1480 nm) absorption. Laser absorption generates surface-tension-driven flows. At the water-air interface, the flows go away from the laser beam (colder region), and at the bottom they go toward the laser (recirculation cell). We use these flows to drag immersed objects toward the laser focus. With laser scanning, several kinds of fluidic patterns can be obtained for specific handlings such as trapping, mixing and sorting of microcomponents. High speed flows can be reached; therefore high velocity particle manipulation can be achieved (several mm/s). Experimental measurements reported a velocity of about 5 mm/s for a spherical glass bead of 90 ¿m in diameter. With these flows, nN range forces are obtained. These forces are about 1000 times larger than forces generated with optical tweezers.
{"title":"Mesoscale-object handling by temperature modulation of surface stresses","authors":"E. Vela, M. Hafez, S. Régnier, S. Bouchigny","doi":"10.1109/MHS.2009.5351741","DOIUrl":"https://doi.org/10.1109/MHS.2009.5351741","url":null,"abstract":"In this work, we present the non-contact manipulation of mesoscale random-shaped, large and heavy objects immersed in thin liquid water (< 0.8 mm). The manipulation principle used is the modulation of surface tension by infra red (IR) laser (1480 nm) absorption. Laser absorption generates surface-tension-driven flows. At the water-air interface, the flows go away from the laser beam (colder region), and at the bottom they go toward the laser (recirculation cell). We use these flows to drag immersed objects toward the laser focus. With laser scanning, several kinds of fluidic patterns can be obtained for specific handlings such as trapping, mixing and sorting of microcomponents. High speed flows can be reached; therefore high velocity particle manipulation can be achieved (several mm/s). Experimental measurements reported a velocity of about 5 mm/s for a spherical glass bead of 90 ¿m in diameter. With these flows, nN range forces are obtained. These forces are about 1000 times larger than forces generated with optical tweezers.","PeriodicalId":344667,"journal":{"name":"2009 International Symposium on Micro-NanoMechatronics and Human Science","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114068022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The purpose of this paper is to create risk management system that multi-agent patrols for maintaining security. We consider that maintaining security is equal to relieving uncertainty. Therefore, we formulate uncertainty of places needed to maintain security by the entropy in an information theory. We call these places ”check point i(i=1,2,…,n)”. Agents patrol and observe check point's condition value with updating patrol schedule on the basis of estimating uncertainty of check points in real time. We propose the method ”Earliest Deadline First Scheduling with Adaptive Risk Estimation(EDFRE)” to relieve uncertainty. Then we compare the proposaled method with simpleEDF(Earliest Deadline First) scheduling. The result indicated that our proposal method was effective for dynamic situation.
{"title":"Risk management system based on uncertainty estimation by multi-agent","authors":"Daichi Kato, K. Sekiyama, T. Fukuda","doi":"10.20965/jrm.2010.p0456","DOIUrl":"https://doi.org/10.20965/jrm.2010.p0456","url":null,"abstract":"The purpose of this paper is to create risk management system that multi-agent patrols for maintaining security. We consider that maintaining security is equal to relieving uncertainty. Therefore, we formulate uncertainty of places needed to maintain security by the entropy in an information theory. We call these places ”check point i(i=1,2,…,n)”. Agents patrol and observe check point's condition value with updating patrol schedule on the basis of estimating uncertainty of check points in real time. We propose the method ”Earliest Deadline First Scheduling with Adaptive Risk Estimation(EDFRE)” to relieve uncertainty. Then we compare the proposaled method with simpleEDF(Earliest Deadline First) scheduling. The result indicated that our proposal method was effective for dynamic situation.","PeriodicalId":344667,"journal":{"name":"2009 International Symposium on Micro-NanoMechatronics and Human Science","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114309286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-12-11DOI: 10.1109/MHS.2009.5352012
Jun Wu, Jian Huang, Yongji Wang, Kexin Xing, Qi Xu
Intensive task-oriented repetitive physical therapies need be provided by individualized interaction between the patients and the rehabilitation specialists to improve hand motor performance for those survived from stoke and traumatic brain injury. The goal of this research is to develop a novel wearable device for robotic assisted hand repetitive therapy. We designed a pneumatic muscle (PM) driven therapeutic device that is wearable and provides assistive forces required for grasping and finger extension. The robot has two distinct degrees of freedom at the thumb and all other fingers. The embedded sensors can feedback position and force information for robot control and quantitative evaluation of task performance. It is potential of providing supplemental at-home therapy in addition to in the clinic treatment. To realize the trajectory tracking control, a fuzzy PID controller is designed for the proposed device. The experimental results show angle tracking control of the robotic hand using the fuzzy PID controller has better performance than that using a conventional PID controller.
{"title":"Fuzzy PID control of a wearable rehabilitation robotic hand driven by pneumatic muscles","authors":"Jun Wu, Jian Huang, Yongji Wang, Kexin Xing, Qi Xu","doi":"10.1109/MHS.2009.5352012","DOIUrl":"https://doi.org/10.1109/MHS.2009.5352012","url":null,"abstract":"Intensive task-oriented repetitive physical therapies need be provided by individualized interaction between the patients and the rehabilitation specialists to improve hand motor performance for those survived from stoke and traumatic brain injury. The goal of this research is to develop a novel wearable device for robotic assisted hand repetitive therapy. We designed a pneumatic muscle (PM) driven therapeutic device that is wearable and provides assistive forces required for grasping and finger extension. The robot has two distinct degrees of freedom at the thumb and all other fingers. The embedded sensors can feedback position and force information for robot control and quantitative evaluation of task performance. It is potential of providing supplemental at-home therapy in addition to in the clinic treatment. To realize the trajectory tracking control, a fuzzy PID controller is designed for the proposed device. The experimental results show angle tracking control of the robotic hand using the fuzzy PID controller has better performance than that using a conventional PID controller.","PeriodicalId":344667,"journal":{"name":"2009 International Symposium on Micro-NanoMechatronics and Human Science","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130048454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-12-11DOI: 10.1109/MHS.2009.5352102
D. Seto, Minoru Watanabe
Demand for fast dynamic reconfiguration has increased since dynamic reconfiguration can accelerate the performance of implementation circuits on its programmable gate array. Such dynamic reconfiguration is dependent upon two important features: fast reconfiguration and numerous contexts. However, fast reconfiguration and numerous contexts share a tradeoff relation on current VLSIs. Therefore, optically recon-figurable gate arrays (ORGAs) have been developed to resolve this dilemma. Among studies of such devices, this paper presents a demonstration of a dynamic ORGA (DORGA) with a MEMS holographic memory and its fault tolerance analysis results.
{"title":"Fault tolerance analysis of MEMS holographic memory for DORGAs","authors":"D. Seto, Minoru Watanabe","doi":"10.1109/MHS.2009.5352102","DOIUrl":"https://doi.org/10.1109/MHS.2009.5352102","url":null,"abstract":"Demand for fast dynamic reconfiguration has increased since dynamic reconfiguration can accelerate the performance of implementation circuits on its programmable gate array. Such dynamic reconfiguration is dependent upon two important features: fast reconfiguration and numerous contexts. However, fast reconfiguration and numerous contexts share a tradeoff relation on current VLSIs. Therefore, optically recon-figurable gate arrays (ORGAs) have been developed to resolve this dilemma. Among studies of such devices, this paper presents a demonstration of a dynamic ORGA (DORGA) with a MEMS holographic memory and its fault tolerance analysis results.","PeriodicalId":344667,"journal":{"name":"2009 International Symposium on Micro-NanoMechatronics and Human Science","volume":"103 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134553779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-12-11DOI: 10.1109/MHS.2009.5352064
H. Zappe
New developments in optical medical diagnostic systems incorporating advanced micro-optical and tunable photonic devices are described. Novel approaches for in vivo blood oxygen monitoring and endoscopic optical coherence tomography are presented.
{"title":"Micro-optical medical monitoring","authors":"H. Zappe","doi":"10.1109/MHS.2009.5352064","DOIUrl":"https://doi.org/10.1109/MHS.2009.5352064","url":null,"abstract":"New developments in optical medical diagnostic systems incorporating advanced micro-optical and tunable photonic devices are described. Novel approaches for in vivo blood oxygen monitoring and endoscopic optical coherence tomography are presented.","PeriodicalId":344667,"journal":{"name":"2009 International Symposium on Micro-NanoMechatronics and Human Science","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131780500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-12-11DOI: 10.1109/MHS.2009.5352030
Y. Sakamoto, F. Takeuchi, M. Miura, Sam-Yong Park, M. Tsubaki
A group of membrane proteins endowed with a single COOH-terminal hydrophobic domain capable of insertion into lipid bilayer is known as tail-anchored (TA) proteins. To clarify the insertion mechanism of the TA-domain of human cytochrome b5 (Hcytb5) having various COOH-terminal extensions with bovine opsin sequence, we constructed expression vectors containing membrane-bound form of Hcytb5 (or Hcytb5op(a), Hcytb5op(b), Hcytb5op(c), and Hcytb5op(d), where NH2-terminal bovine opsin sequences with various truncated forms were attached at the COOH-terminus) and established a method for their expression and purification in the holo-form. We analyzed the integration of the TA domain of holo-form of Hcytb5 into protein-free liposomes. The integration of holo- Hcytb5 occurred efficiently into the membranes with a low cholesterol content even in the presence of a small amount of Triton X−100 and, once incorporated, the proteoliposomes were relatively stable.
一组具有单一cooh末端疏水结构域的膜蛋白被称为尾部锚定(TA)蛋白。为了明确具有不同cooh末端延伸的人细胞色素b5 (Hcytb5) ta结构域与牛视蛋白序列的插入机制，我们构建了含有膜结合形式的Hcytb5(或Hcytb5op(a)、Hcytb5op(b)、Hcytb5op(c)和Hcytb5op(d)的表达载体，其中不同截断形式的nh2末端牛视蛋白序列连接在cooh末端)，并建立了其全形式表达和纯化方法。我们分析了Hcytb5全息形式的TA结构域与无蛋白脂质体的整合。即使在少量Triton X - 100存在的情况下，holo- Hcytb5也能有效地整合到低胆固醇含量的膜中，并且一旦整合，蛋白脂质体相对稳定。
{"title":"Preparation of cytochromes b5 with an extended COOH-terminal hydrophilic segment: Interaction of modified tail-anchored proteins with liposomes in different cholesterol content","authors":"Y. Sakamoto, F. Takeuchi, M. Miura, Sam-Yong Park, M. Tsubaki","doi":"10.1109/MHS.2009.5352030","DOIUrl":"https://doi.org/10.1109/MHS.2009.5352030","url":null,"abstract":"A group of membrane proteins endowed with a single COOH-terminal hydrophobic domain capable of insertion into lipid bilayer is known as tail-anchored (TA) proteins. To clarify the insertion mechanism of the TA-domain of human cytochrome b5 (Hcytb5) having various COOH-terminal extensions with bovine opsin sequence, we constructed expression vectors containing membrane-bound form of Hcytb5 (or Hcytb5op(a), Hcytb5op(b), Hcytb5op(c), and Hcytb5op(d), where NH2-terminal bovine opsin sequences with various truncated forms were attached at the COOH-terminus) and established a method for their expression and purification in the holo-form. We analyzed the integration of the TA domain of holo-form of Hcytb5 into protein-free liposomes. The integration of holo- Hcytb5 occurred efficiently into the membranes with a low cholesterol content even in the presence of a small amount of Triton X−100 and, once incorporated, the proteoliposomes were relatively stable.","PeriodicalId":344667,"journal":{"name":"2009 International Symposium on Micro-NanoMechatronics and Human Science","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132701099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-12-11DOI: 10.1109/MHS.2009.5351912
Y. Naito, K. Nishi, Aya Juni, K. Ui-Tei
The capability to induce off-target effects by small interfering RNA (siRNA) is highly correlated with the calculated melting temperature (Tm) of the protein-free seed-target duplex, indicating that its thermodynamic stability is a major factor in determining the degree of the off-target effect. In this study, we analyzed changes in microarray expression profiles following transfection of short hairpin RNAs (shRNAs). In a similar manner to siRNA, no or little off-target effects were observed by shRNA with a low Tm value in the seed-target duplex, whereas a high degree of off-target effect was induced by shRNA with a high Tm. Furthermore, shRNAs were often cleaved by Drosha and/or Dicer at the shifted sites in their primary transcripts, resulting in unexpected siRNA products with shifted sequences. Based on these results, the following conditions should be satisfied to ensure a functional shRNA with reduced off-target effects: the presence of A/U residues at nucleo tide positions 1 and −1 from the 5' end of the guide strand, three to six A/Us in nucleotide positions 2–7, G/C at positions 19 and 18, and no GC stretch of more than nine nucleotides. In addition, the Tm values of the seed regions in both strands should be low.
{"title":"Functional shRNA expression system with reduced off-target effects","authors":"Y. Naito, K. Nishi, Aya Juni, K. Ui-Tei","doi":"10.1109/MHS.2009.5351912","DOIUrl":"https://doi.org/10.1109/MHS.2009.5351912","url":null,"abstract":"The capability to induce off-target effects by small interfering RNA (siRNA) is highly correlated with the calculated melting temperature (Tm) of the protein-free seed-target duplex, indicating that its thermodynamic stability is a major factor in determining the degree of the off-target effect. In this study, we analyzed changes in microarray expression profiles following transfection of short hairpin RNAs (shRNAs). In a similar manner to siRNA, no or little off-target effects were observed by shRNA with a low Tm value in the seed-target duplex, whereas a high degree of off-target effect was induced by shRNA with a high Tm. Furthermore, shRNAs were often cleaved by Drosha and/or Dicer at the shifted sites in their primary transcripts, resulting in unexpected siRNA products with shifted sequences. Based on these results, the following conditions should be satisfied to ensure a functional shRNA with reduced off-target effects: the presence of A/U residues at nucleo tide positions 1 and −1 from the 5' end of the guide strand, three to six A/Us in nucleotide positions 2–7, G/C at positions 19 and 18, and no GC stretch of more than nine nucleotides. In addition, the Tm values of the seed regions in both strands should be low.","PeriodicalId":344667,"journal":{"name":"2009 International Symposium on Micro-NanoMechatronics and Human Science","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114319928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-12-11DOI: 10.1109/MHS.2009.5351991
Yalikun Yaxar, T. Hoshino, K. Morishima
We propose a new Bio-manipulation method which is based on micro hydrodynamics. Compare with other present bio-manipulation methods, our system which do not directly contact with cell is no-harmful and soft manipulation. The system implements its function by controlling a small a amount of volume of liquid stream. For manufacture the prototype to confirm the basic principle of our idea, we design several sample models to simulate force and direction of liquid stream using CFD software. As a result, we succeed in manufactured the prototype. Obtained several kinds of rectilinear motion for confirm our principle.
{"title":"Design of bio-manipulation with micro water jet","authors":"Yalikun Yaxar, T. Hoshino, K. Morishima","doi":"10.1109/MHS.2009.5351991","DOIUrl":"https://doi.org/10.1109/MHS.2009.5351991","url":null,"abstract":"We propose a new Bio-manipulation method which is based on micro hydrodynamics. Compare with other present bio-manipulation methods, our system which do not directly contact with cell is no-harmful and soft manipulation. The system implements its function by controlling a small a amount of volume of liquid stream. For manufacture the prototype to confirm the basic principle of our idea, we design several sample models to simulate force and direction of liquid stream using CFD software. As a result, we succeed in manufactured the prototype. Obtained several kinds of rectilinear motion for confirm our principle.","PeriodicalId":344667,"journal":{"name":"2009 International Symposium on Micro-NanoMechatronics and Human Science","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114767157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-12-11DOI: 10.1109/MHS.2009.5351935
Daiki Kawakami, K. Ohara, Y. Mae, T. Takubo, T. Tanikawa, T. Arai
In this paper, user-friendly micro manipulation system for the bio-medical scientist is introduced. An operator usually is not familiar with robot technology. However, supports for RT system have great means for such users. So, user friendly system architecture is necessary to provide useful operation scheme. In this paper, the component-based architecture for micro manipulation system is proposed. Realizing component-based architecture, OpenRTM-aist, which is one of the robot middleware, is focused. And, based on this middleware, micro manipulation system and observation system are constructed as examples.
{"title":"User friendly two-fingered cell manipulation system","authors":"Daiki Kawakami, K. Ohara, Y. Mae, T. Takubo, T. Tanikawa, T. Arai","doi":"10.1109/MHS.2009.5351935","DOIUrl":"https://doi.org/10.1109/MHS.2009.5351935","url":null,"abstract":"In this paper, user-friendly micro manipulation system for the bio-medical scientist is introduced. An operator usually is not familiar with robot technology. However, supports for RT system have great means for such users. So, user friendly system architecture is necessary to provide useful operation scheme. In this paper, the component-based architecture for micro manipulation system is proposed. Realizing component-based architecture, OpenRTM-aist, which is one of the robot middleware, is focused. And, based on this middleware, micro manipulation system and observation system are constructed as examples.","PeriodicalId":344667,"journal":{"name":"2009 International Symposium on Micro-NanoMechatronics and Human Science","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114918584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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