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The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.最新文献

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Optical coherence tomography (OCT) findings following photodynamic therapy (PDT) in ophthalmology 光学相干断层扫描(OCT)在眼科光动力治疗(PDT)后的发现
Pub Date : 2004-12-15 DOI: 10.1109/APBP.2004.1412279
Photodynamic therapy is an effective treatment for wet form macular degeneration. Besides fluorescein angiography, optical coherence tomography can monitor fluid level lesion size changes and detect retinal pigment epithelium detachment after treatment.
光动力疗法是治疗湿型黄斑变性的有效方法。除了荧光素血管造影外,光学相干断层扫描还可以监测治疗后的液位病变大小变化和视网膜色素上皮脱离。
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引用次数: 1
Evanescent planar wave system for reading DNA microarrays on thin glass slides 用于读取薄玻片上DNA微阵列的倏逝平面波系统
Pub Date : 2004-12-15 DOI: 10.1109/APBP.2004.1412369
A new optical reading system that can read the fluorescent signals of microarrays on glass slides with large detection area and high sensitivity is proposed. This system uses gratings (1200 g/mm) with several micron thick PDMS film on surface. Normally incident laser was coupled into a thin glass slide by grating coupling and confined in the slide due to the total internal reflection (TIR). The TIR generates evanescent planar wave on the glass surface. The evanescent wave was employed to excite the fluorescent signals in the microarrays. The method takes the advantages of low excitation background, large and uniform detection area.
提出了一种新的光学读取系统,可以读取大检测面积、高灵敏度的玻片上微阵列的荧光信号。该系统使用光栅(1200g /mm),表面有几微米厚的PDMS薄膜。正常入射的激光通过光栅耦合耦合到薄玻片上,并由于全内反射(TIR)而被限制在玻片内。红外光谱在玻璃表面产生倏逝平面波。利用倏逝波激发微阵列中的荧光信号。该方法具有激发背景低、检测面积大、均匀等优点。
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引用次数: 3
Real-time imaging of muscle oxygenation using spatially resolved near-infrared spectroscopy 利用空间分辨近红外光谱实时成像肌肉氧合
Pub Date : 2004-12-15 DOI: 10.1109/APBP.2004.1412262
We have developed a spatially resolved NIRS imaging system with novel optical probes and fast temporal resolution. Initial results showed the effectiveness of our system for real-time spatio-temporal analyses for muscle oxygenation during exercises.
我们开发了一种具有新型光学探针和快速时间分辨率的空间分辨近红外成像系统。初步结果表明,我们的系统对运动过程中肌肉氧合的实时时空分析是有效的。
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引用次数: 2
Application of differential phase detection for sensitivity improvement in surface plasmon resonance sensors 差分相位检测在表面等离子体共振传感器灵敏度提高中的应用
Pub Date : 2004-12-15 DOI: 10.1109/APBP.2004.1412361
Surface plasmon resonance (SPR) is an effective tool for quantitative detection of binding reaction between biomolecules. Currently SPR sensors are mainly based on measuring the angular shift associated with biomolecular adhesion. In fact it has been shown that the phase jump across the SPR dip is very steep, and consequently better sensitivity may be achieved by measuring the optical phase. In this presentation, we report interferometric techniques we have developed in our laboratory for achieving SPR phase detection. We also demonstrate that the incorporation of differential phase detection can further improve the performance of SPR biosensors. Currently the experimental sensitivity of our differential phase setup is 5.48/spl times/10/sup -8/ refractive index unit (RIU), which is three times better than that reported from conventional angular systems.
表面等离子体共振(SPR)是定量检测生物分子间结合反应的有效工具。目前SPR传感器主要是基于测量与生物分子粘附相关的角位移。事实上,已经证明,在SPR倾角上的相位跳跃非常陡峭,因此通过测量光学相位可以获得更好的灵敏度。在本报告中,我们报告了我们在实验室开发的用于实现SPR相位检测的干涉测量技术。我们还证明了差分相位检测的结合可以进一步提高SPR生物传感器的性能。目前,我们的差分相位装置的实验灵敏度为5.48/spl倍/10/sup -8/折射率单位(RIU),是传统角度系统的3倍。
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引用次数: 1
Raman spectroscopic detection of silicone leakage in human breast and lymph node tissues 拉曼光谱检测人体乳腺及淋巴结组织中硅酮渗漏
Pub Date : 2004-12-15 DOI: 10.1109/APBP.2004.1412261
Raman spectroscopy was utilized to study surgical excision specimens of human breast and lymph node tissues from patients with leaking silicone bag-gel breast implants. This may offer a new method of detection to evaluate tissues.
利用拉曼光谱对硅胶袋凝胶乳房植入物泄漏患者的乳腺切除标本和淋巴结组织进行了研究。这可能为评估组织提供一种新的检测方法。
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引用次数: 1
Polarization measurement of backscattering from turbid media: simulation and experiment 混浊介质后向散射的偏振测量:模拟与实验
Pub Date : 2004-12-15 DOI: 10.1109/APBP.2004.1412260
We propose a Monte Carlo method which can simulate scattering of polarized light in sphere suspension and also present a basic system for 2-D angular pattern of the backscattering light from turbid media. The experimental results of polystyrene sphere suspension coincide well with the simulation results.
我们提出了一种蒙特卡罗方法来模拟偏振光在球悬液中的散射,并给出了浑浊介质中后向散射光的二维角图的基本体系。聚苯乙烯球悬浮液的实验结果与仿真结果吻合较好。
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引用次数: 0
Femtosecond lasers for medical applications 医疗用飞秒激光器
Pub Date : 2004-12-15 DOI: 10.1109/APBP.2004.1412364
Femtosecond lasers have been developed for biomedical applications.
飞秒激光器已被开发用于生物医学应用。
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引用次数: 0
Endoscopic laser surgery in pediatric airway management 内镜激光手术在儿童气道管理中的应用
Pub Date : 2004-12-15 DOI: 10.1109/APBP.2004.1412303
Pediatric airway management is a life-threatening problem for children and always a challenge to pediatric otolaryngologists. Endoscopic techniques for evaluation and management of airway in pediatric patients have matured greatly in the past decade, especially with the introduction of Laser instrumentation. For example, to treat severe laryngomalacia, subglottic hemangioma, laryngeal papillomatosis, granuloma or web, subglottic or tracheal stenosis, bilateral vocal fold paralysis, tracheobronchial tumor etc. were all effective in selective cases. These developments have been proved that pediatric endoscopic laser surgery can be performed in the airway safely and effectively when a team approach is used. The appropriate choice of laser instruments, anesthesia access, post-operation intensive cares, cooperation and understanding of families were all essential factors for a successful endoscopic laser surgery in pediatric airway management.
儿科气道管理是危及儿童生命的问题,也是儿科耳鼻喉科医生面临的一个挑战。在过去的十年中,特别是随着激光仪器的引入,用于评估和管理儿科患者气道的内镜技术已经非常成熟。如治疗重度喉软化、声门下血管瘤、喉乳头状瘤、肉芽肿或网状、声门下或气管狭窄、双侧声带麻痹、气管支气管肿瘤等均有选择性有效。这些进展已经证明,当采用团队方法时,儿童内窥镜激光手术可以安全有效地在气道中进行。选择合适的激光器械、麻醉途径、术后重症监护、家属的配合和理解是内镜下激光手术治疗儿童气道成功的关键因素。
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引用次数: 0
Study on digital imaging colorimeter in dermatology 数字成像色度计在皮肤病学中的应用研究
Pub Date : 2004-12-15 DOI: 10.1109/APBP.2004.1412323
In this paper, we introduced an improved digital imaging measurement system on skin diseases diagnosis Then basing on analysis of a large amount of clinical cases on skin diseases, we corrected the HSV color space in order to analyze characteristics of the color on disease skin. On the end, we examined the meaning of three indexes through analysis of some clinical cases.
本文介绍了一种改进的皮肤病诊断数字成像测量系统,在分析大量皮肤病临床病例的基础上,对HSV颜色空间进行校正,分析疾病皮肤的颜色特征。最后,通过对部分临床病例的分析,探讨三项指标的意义。
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引用次数: 2
Coherent antiStokes Raman microscope for identification of cellular molecule 用于细胞分子鉴定的相干反斯托克斯拉曼显微镜
Pub Date : 2004-12-15 DOI: 10.1109/APBP.2004.1412368
Coherent antiStokes Raman scattering (CARS) microscope is a new molecular identification tool with high spatial resolution. Nonstaining molecular identification is achieved by observing the molecular vibrations any molecule have, and high spatial resolution image is obtained by the nonlinear optical process. We have developed the far-field and near-field CARS microscopy systems for three dimensional imaging and ultra-high resolution imaging.
相干反斯托克斯拉曼散射(CARS)显微镜是一种新型的高空间分辨率分子识别工具。该方法通过观察分子的振动来实现无染色分子识别,并通过非线性光学处理获得高空间分辨率的图像。我们开发了用于三维成像和超高分辨率成像的远场和近场CARS显微镜系统。
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引用次数: 0
期刊
The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.
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