Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412299
Zhiwei Huang, H. Lui, D. McLean, M. Korbelik, H. Zeng
This study evaluated and compared the diagnostic ability of near-infrared (NIR) autofluorescence spectroscopy, NIR Raman spectroscopy, and the superimposed Raman and NIR autofluorescence spectroscopy for in vivo detection of malignant tumors using a murine model.
{"title":"Combining Raman spectroscopy with background near-infrared autofluorescence to improve the noninvasive detection of malignant tumors","authors":"Zhiwei Huang, H. Lui, D. McLean, M. Korbelik, H. Zeng","doi":"10.1109/APBP.2004.1412299","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412299","url":null,"abstract":"This study evaluated and compared the diagnostic ability of near-infrared (NIR) autofluorescence spectroscopy, NIR Raman spectroscopy, and the superimposed Raman and NIR autofluorescence spectroscopy for in vivo detection of malignant tumors using a murine model.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"354 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132554384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412248
S. Bown
Photodynamic therapy (PDT) has evolved recently by the availability of lasers and optical fibres suitable for light delivery to many sites within the body, and synthesis of more effective photosensitizers. From a clinical point of view, PDT is a way of producing localised tissue destruction with light. One of the most striking aspects of PDT induced tissue destruction is that connective tissues like collagen and elastin are largely unaffected. PDT offers many challenges and opportunities for existing and new optical technologies, including lasers. The basic principle can be applied to disease processes in a wide range of organs. The secret to making the most of this evolving new therapeutic modality is to understand the biology of what PDT can do to living tissue, identify when that is relevant to the treatment of human disease and then ensure that adequate drug and light doses are delivered to all relevant sites.
{"title":"Scientists and clinicians create a bright future for photodynamic therapy (PDT)","authors":"S. Bown","doi":"10.1109/APBP.2004.1412248","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412248","url":null,"abstract":"Photodynamic therapy (PDT) has evolved recently by the availability of lasers and optical fibres suitable for light delivery to many sites within the body, and synthesis of more effective photosensitizers. From a clinical point of view, PDT is a way of producing localised tissue destruction with light. One of the most striking aspects of PDT induced tissue destruction is that connective tissues like collagen and elastin are largely unaffected. PDT offers many challenges and opportunities for existing and new optical technologies, including lasers. The basic principle can be applied to disease processes in a wide range of organs. The secret to making the most of this evolving new therapeutic modality is to understand the biology of what PDT can do to living tissue, identify when that is relevant to the treatment of human disease and then ensure that adequate drug and light doses are delivered to all relevant sites.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116990340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412370
Yen-Sheng Lu, Yuan-Peng Huang, J. Yeh, Chengkuo Lee
We demonstrated a novel approach to trigger the dielectrophoretic force to manipulate biological cells via projected flash images. The attractive and repulsive force regions are formed due to effectively initiated dielectrophoretic force, where these regions are the bright and dark area among a projected image on a liquid reservoir depending on the polarization states. In present study, the attractive force draw in live cells, saccharomyces cerevisiae, and live cells can be manipulated inside reservoir without any microchannel confinement in a programmable manner. The relation between distance from the boundary and average velocity is also discussed.
{"title":"Image driven cell manipulation using optical dielectrophoresis (ODEP)","authors":"Yen-Sheng Lu, Yuan-Peng Huang, J. Yeh, Chengkuo Lee","doi":"10.1109/APBP.2004.1412370","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412370","url":null,"abstract":"We demonstrated a novel approach to trigger the dielectrophoretic force to manipulate biological cells via projected flash images. The attractive and repulsive force regions are formed due to effectively initiated dielectrophoretic force, where these regions are the bright and dark area among a projected image on a liquid reservoir depending on the polarization states. In present study, the attractive force draw in live cells, saccharomyces cerevisiae, and live cells can be manipulated inside reservoir without any microchannel confinement in a programmable manner. The relation between distance from the boundary and average velocity is also discussed.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"198 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115491634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412335
Chia-Wei Sun, Cheng-Kuang Lee, Hsiang-Chieh Lee, Po-Lei Lee, C.C. Yang, Cho-Pei Jiang, Tsz-Yi Yang, Y. Tong, J. Hsieh
We demonstrate the utility of near-infrared spectroscopy in monitoring of the human visual cortex. The typical hemodynamic signals expected are observed in our preliminary experiments.
我们展示了近红外光谱在监测人类视觉皮层中的效用。我们在初步实验中观察到预期的典型血流动力学信号。
{"title":"Near-infrared spectroscopy studies of visual evoked responses during photon stimulation","authors":"Chia-Wei Sun, Cheng-Kuang Lee, Hsiang-Chieh Lee, Po-Lei Lee, C.C. Yang, Cho-Pei Jiang, Tsz-Yi Yang, Y. Tong, J. Hsieh","doi":"10.1109/APBP.2004.1412335","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412335","url":null,"abstract":"We demonstrate the utility of near-infrared spectroscopy in monitoring of the human visual cortex. The typical hemodynamic signals expected are observed in our preliminary experiments.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121156915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412267
S. Wang, Lanqing Xu, Hui Li, Y. Yamada
Monte Carlo method was used to simulate the propagation behavior of 2-D Stokes vectors and Mueller matrices under various conditions. The effect of different incident polarization states, tissue optical parameters and Fresnel matrices at the boundary are fully considered.
{"title":"Diffusely scattered polarized light in turbid media: Monte Carlo Simulation","authors":"S. Wang, Lanqing Xu, Hui Li, Y. Yamada","doi":"10.1109/APBP.2004.1412267","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412267","url":null,"abstract":"Monte Carlo method was used to simulate the propagation behavior of 2-D Stokes vectors and Mueller matrices under various conditions. The effect of different incident polarization states, tissue optical parameters and Fresnel matrices at the boundary are fully considered.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"203 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123967667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412271
S. Fukushima, T. Araki, Y. Sakaguchi, Y. Tohno
Calcium content in vascular wall at arterial bifurcation was measured with atomic emission spectrometry, and blood flow in the bifurcation was simulated by computational fluid dynamics. The results suggested hemodynamic factors affect vascular wall calcification.
{"title":"Relationship between calcium content and hemodynamics at arterial bifurcation","authors":"S. Fukushima, T. Araki, Y. Sakaguchi, Y. Tohno","doi":"10.1109/APBP.2004.1412271","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412271","url":null,"abstract":"Calcium content in vascular wall at arterial bifurcation was measured with atomic emission spectrometry, and blood flow in the bifurcation was simulated by computational fluid dynamics. The results suggested hemodynamic factors affect vascular wall calcification.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128635639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412287
Yuan Liu, Hsuan-Shu Lee, Hsiao-Ching Chen, L. Chiou, Guan-Tarn Huang, Wen Lo, C. Dong
In this work, we apply multiphoton microscopy in diagnosing toxin (CCl/sub 4/) induced liver fibrosis in mice. We found that multiphoton induced spectroscopic signatures may be used to identify stellate cell proliferation and necrotic sites. Our study suggests that multiphoton imaging may be developed into an effective diagnosis tool for liver fibrosis in vivo.
{"title":"Optical biopsy of liver fibrosis using multiphoton microscopy","authors":"Yuan Liu, Hsuan-Shu Lee, Hsiao-Ching Chen, L. Chiou, Guan-Tarn Huang, Wen Lo, C. Dong","doi":"10.1109/APBP.2004.1412287","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412287","url":null,"abstract":"In this work, we apply multiphoton microscopy in diagnosing toxin (CCl/sub 4/) induced liver fibrosis in mice. We found that multiphoton induced spectroscopic signatures may be used to identify stellate cell proliferation and necrotic sites. Our study suggests that multiphoton imaging may be developed into an effective diagnosis tool for liver fibrosis in vivo.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130261820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412372
Liang Yu Yao, Chien-Chih Huang, K. Weng, Chien-Cheng Yang, Chia-Wei Sun, M. Tsai, C.C. Yang
To miniaturize the system, we use an LED and a pin photodetector for light-induced fluorescence detection of capillary electrophoreses. To overcome the drawback of low gain in a photodetector, we use the technique of lock-in amplification.
{"title":"A microcapillary electrophoreses fluorescence detection system with a blue-light-emitting diode as light source","authors":"Liang Yu Yao, Chien-Chih Huang, K. Weng, Chien-Cheng Yang, Chia-Wei Sun, M. Tsai, C.C. Yang","doi":"10.1109/APBP.2004.1412372","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412372","url":null,"abstract":"To miniaturize the system, we use an LED and a pin photodetector for light-induced fluorescence detection of capillary electrophoreses. To overcome the drawback of low gain in a photodetector, we use the technique of lock-in amplification.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130810456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412307
Hsin-Cheng Liu, W. Lan
The aim of this study was to evaluate the effectiveness of diode laser combined with glass ionomer cement in the treatment of cervical dentin abrasion hypersensitivity.
本研究的目的是评价二极管激光联合玻璃离聚体骨水泥治疗颈牙本质磨损超敏反应的有效性。
{"title":"Treatment of cervical dentin abrasion hypersensitivity by diode laser and glass ionomer cement","authors":"Hsin-Cheng Liu, W. Lan","doi":"10.1109/APBP.2004.1412307","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412307","url":null,"abstract":"The aim of this study was to evaluate the effectiveness of diode laser combined with glass ionomer cement in the treatment of cervical dentin abrasion hypersensitivity.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127648429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412368
M. Hashimoto
Coherent antiStokes Raman scattering (CARS) microscope is a new molecular identification tool with high spatial resolution. Nonstaining molecular identification is achieved by observing the molecular vibrations any molecule have, and high spatial resolution image is obtained by the nonlinear optical process. We have developed the far-field and near-field CARS microscopy systems for three dimensional imaging and ultra-high resolution imaging.
{"title":"Coherent antiStokes Raman microscope for identification of cellular molecule","authors":"M. Hashimoto","doi":"10.1109/APBP.2004.1412368","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412368","url":null,"abstract":"Coherent antiStokes Raman scattering (CARS) microscope is a new molecular identification tool with high spatial resolution. Nonstaining molecular identification is achieved by observing the molecular vibrations any molecule have, and high spatial resolution image is obtained by the nonlinear optical process. We have developed the far-field and near-field CARS microscopy systems for three dimensional imaging and ultra-high resolution imaging.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114313614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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