Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412318
Stephane Paes, S. Ryu, Jihoon Na, EunSeo Choi, Changsu Lee, B. Lee
Coherence of light commonly used in optical coherence tomography can induce axial resolution loss and speckle generation. Combined use of iterative deconvolution methods and adaptive speckle filters can significantly reduce it and give clearer images.
{"title":"Combined applications of iterative deconvolution methods and adaptive speckle filters for optical coherence tomography","authors":"Stephane Paes, S. Ryu, Jihoon Na, EunSeo Choi, Changsu Lee, B. Lee","doi":"10.1109/APBP.2004.1412318","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412318","url":null,"abstract":"Coherence of light commonly used in optical coherence tomography can induce axial resolution loss and speckle generation. Combined use of iterative deconvolution methods and adaptive speckle filters can significantly reduce it and give clearer images.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130708725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412339
Yen Sun, Sung-Jan Lin, Chih-Yuan Hsiao, Wen Lo, S. Jee, C. Dong
In this work, the thermal disruption of type I collagen is investigated using second harmonic generation (SHG) microscopy. We investigated the effects of second harmonic generation images and intensity of rat tail tendon in the temperature range from 25 to 60/spl deg/C. We found a structural transition at 57/spl deg/C where a drop in second harmonic intensity is correlated to a disorganization of the collagen fibers. Our results suggest that SHG microscopy is an effective technique to monitor thermally induced collagen structural changes for biomedical applications.
{"title":"An investigation of thermally induced collagen structural transitions by second harmonic generation microscopy","authors":"Yen Sun, Sung-Jan Lin, Chih-Yuan Hsiao, Wen Lo, S. Jee, C. Dong","doi":"10.1109/APBP.2004.1412339","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412339","url":null,"abstract":"In this work, the thermal disruption of type I collagen is investigated using second harmonic generation (SHG) microscopy. We investigated the effects of second harmonic generation images and intensity of rat tail tendon in the temperature range from 25 to 60/spl deg/C. We found a structural transition at 57/spl deg/C where a drop in second harmonic intensity is correlated to a disorganization of the collagen fibers. Our results suggest that SHG microscopy is an effective technique to monitor thermally induced collagen structural changes for biomedical applications.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"187 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133446776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412314
Hsiang-Chieh Lee, Cheng-Kuan Lee, Chia-Wei Sun, Liang Yu Yao, Y. Kiang, C.C. Yang
For understanding the correlations between temporal and spatial photon distributions in the process of random scattering in turbid media, the Monte Carlo algorithm is used to describe various optical gating conditions. We study the distributions of transmitted photon with time-, aperture-, and angle-gating techniques. We record the optical paths of transmitted photons with different aperture sizes and angles. Time-resolved profiles and polarization states of transmitted photons are also discussed.
{"title":"Correlations between temporal and spatial photon distributions in turbid media: Monte-Carlo modeling of time-, aperture-, angle-, and polarization-gating methods","authors":"Hsiang-Chieh Lee, Cheng-Kuan Lee, Chia-Wei Sun, Liang Yu Yao, Y. Kiang, C.C. Yang","doi":"10.1109/APBP.2004.1412314","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412314","url":null,"abstract":"For understanding the correlations between temporal and spatial photon distributions in the process of random scattering in turbid media, the Monte Carlo algorithm is used to describe various optical gating conditions. We study the distributions of transmitted photon with time-, aperture-, and angle-gating techniques. We record the optical paths of transmitted photons with different aperture sizes and angles. Time-resolved profiles and polarization states of transmitted photons are also discussed.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"30 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114110181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412286
P. So, T. Ragan, K. Bahlmann, H. Kwon, H. Huang, J. Sylvan, R.T. Lee
We developed 3D tissue image cytometry for the imaging of whole organs with subcellular resolution. This technique potentially allows tissue physiology to be understood on the basis of the underlying genomics and proteomics.
{"title":"Tissue image cytometry: whole organ imaging with subcellular resolution","authors":"P. So, T. Ragan, K. Bahlmann, H. Kwon, H. Huang, J. Sylvan, R.T. Lee","doi":"10.1109/APBP.2004.1412286","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412286","url":null,"abstract":"We developed 3D tissue image cytometry for the imaging of whole organs with subcellular resolution. This technique potentially allows tissue physiology to be understood on the basis of the underlying genomics and proteomics.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114245858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412344
Shu-Jen Kuo, Wen Lo, C. Dong
Due to the growing importance of optical imaging in tissue diagnosis, we use multiphoton microscopy, to characterize normal and cancerous oral tissues. We acquired both microscopic and spectroscopic data for the characterization of normal and cancerous oral tissues. Our results show that both multiphoton fluorescence and harmonic generation images may be used to distinguish both tissue types. An image of different oral tissues will be of value for clinicians in the diagnosis and treatment of oral diseases.
{"title":"Imaging of human oral cancer using multiphoton microscopy","authors":"Shu-Jen Kuo, Wen Lo, C. Dong","doi":"10.1109/APBP.2004.1412344","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412344","url":null,"abstract":"Due to the growing importance of optical imaging in tissue diagnosis, we use multiphoton microscopy, to characterize normal and cancerous oral tissues. We acquired both microscopic and spectroscopic data for the characterization of normal and cancerous oral tissues. Our results show that both multiphoton fluorescence and harmonic generation images may be used to distinguish both tissue types. An image of different oral tissues will be of value for clinicians in the diagnosis and treatment of oral diseases.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"345 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131930398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412334
Y. Nakamura, K. Pilt, N. Kakuta, H. Arimoto, Y. Yamada
It is necessary for more appropriate hemodialysis treatment to know water content in tissue. We measured water content of Intralipid-20% solution, which has similar optical properties to those of tissue, and showed the possibility to measure the water content in tissue in vivo.
{"title":"Optical measurement of water content in tissue","authors":"Y. Nakamura, K. Pilt, N. Kakuta, H. Arimoto, Y. Yamada","doi":"10.1109/APBP.2004.1412334","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412334","url":null,"abstract":"It is necessary for more appropriate hemodialysis treatment to know water content in tissue. We measured water content of Intralipid-20% solution, which has similar optical properties to those of tissue, and showed the possibility to measure the water content in tissue in vivo.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"206 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132270471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412249
T. Vo‐Dinh
This lecture provides an overview of the research activities in our laboratory related to the development and application of advanced biomedical photonics, molecular spectroscopy, nanosensors and biochips for biomedical diagnostics.
{"title":"Advanced biophotonics: from biochips to nanosensors","authors":"T. Vo‐Dinh","doi":"10.1109/APBP.2004.1412249","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412249","url":null,"abstract":"This lecture provides an overview of the research activities in our laboratory related to the development and application of advanced biomedical photonics, molecular spectroscopy, nanosensors and biochips for biomedical diagnostics.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133216966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412345
Ruei-Jhih Wu, Sung-Jan Lin, C. Dong
This work focuses on using multiphoton microscopy for classifying and characterizing the infectious fungi in dermatology. We imaged and found that four fungi, M.canis T.menta Fusariun Asp.flavus, can be identified using multiphoton imaging and that their luminescence is located in blue and green part of the spectrum.
{"title":"Multiphoton identification of infectious fungi in dermatology","authors":"Ruei-Jhih Wu, Sung-Jan Lin, C. Dong","doi":"10.1109/APBP.2004.1412345","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412345","url":null,"abstract":"This work focuses on using multiphoton microscopy for classifying and characterizing the infectious fungi in dermatology. We imaged and found that four fungi, M.canis T.menta Fusariun Asp.flavus, can be identified using multiphoton imaging and that their luminescence is located in blue and green part of the spectrum.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123623798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412349
W. Kuo, C. Lai, C. Chou, Huan-Jang Huang, G. Jan
We report a method for extracting the birefringence properties of samples with a novel proposed polarization-sensitive optical coherence tomography (PS-OCT) using linearly polarized incident light.
{"title":"Comparative study of linearly and circularly polarized light in polarization-sensitive optical coherence tomography","authors":"W. Kuo, C. Lai, C. Chou, Huan-Jang Huang, G. Jan","doi":"10.1109/APBP.2004.1412349","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412349","url":null,"abstract":"We report a method for extracting the birefringence properties of samples with a novel proposed polarization-sensitive optical coherence tomography (PS-OCT) using linearly polarized incident light.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127108326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412282
Shih-Jen Chen
This presentation will introduce the photodynamic therapy in Taiwan (Verteporfin In Taiwan - VITA) results and summarize the results of PDT for patients with CNV secondary to pathological myopia in a tertiary medical center.
{"title":"Experience of photodynamic therapy for choroidal neovascularization in Taiwan","authors":"Shih-Jen Chen","doi":"10.1109/APBP.2004.1412282","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412282","url":null,"abstract":"This presentation will introduce the photodynamic therapy in Taiwan (Verteporfin In Taiwan - VITA) results and summarize the results of PDT for patients with CNV secondary to pathological myopia in a tertiary medical center.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127467777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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