Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412253
M. Akiba, K. Chan
Full-field optical coherence tomography (OCT) is demonstrated using a parallel heterodyne detection technique with a pair of CCD cameras. A series of depth-resolved horizontal cross-sectional OCT images are acquired at 100 frames/s in a single longitudinal scan.
{"title":"Video-rate, full-field OCT imaging using a dual-channel parallel heterodyne detection technique","authors":"M. Akiba, K. Chan","doi":"10.1109/APBP.2004.1412253","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412253","url":null,"abstract":"Full-field optical coherence tomography (OCT) is demonstrated using a parallel heterodyne detection technique with a pair of CCD cameras. A series of depth-resolved horizontal cross-sectional OCT images are acquired at 100 frames/s in a single longitudinal scan.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125871533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412265
Shu-Fan Chen, Chih-Wei Lu, Yih-ming Wang, M. Tsai, C.C. Yang, C. Chiang
We use optical coherence tomography (OCT) with a specially designed probe to structurally image the tissue within the oral cavity. We have imaged different types of healthy oral mucosa, including masticatory mucosa in gingiva and lining mucosa in buccal mucosa. OCT can be used to differentiate between the various types of keratinized and nonkeratinized mucosa with high resolution.
{"title":"In vivo OCT imaging of oral cavity tissues","authors":"Shu-Fan Chen, Chih-Wei Lu, Yih-ming Wang, M. Tsai, C.C. Yang, C. Chiang","doi":"10.1109/APBP.2004.1412265","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412265","url":null,"abstract":"We use optical coherence tomography (OCT) with a specially designed probe to structurally image the tissue within the oral cavity. We have imaged different types of healthy oral mucosa, including masticatory mucosa in gingiva and lining mucosa in buccal mucosa. OCT can be used to differentiate between the various types of keratinized and nonkeratinized mucosa with high resolution.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"292 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123111822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412351
T. Kimura, N. Muguruma, S. Ito, H. Yano, Y. Imoto, K. Okamoto, M. Kaji, S. Okamura
An infrared fluorescence endoscope (IRFE) was used to evaluate several kinds of gastrointestinal lesions under indocyanine-green (ICG) administration. It may be useful as a novel diagnostic procedure for vascular lesions occurring in the gastrointestinal tract.
{"title":"A novel diagnostic endoscopy for gastrointestinal lesions using infrared fluorescence and indocyanine-green","authors":"T. Kimura, N. Muguruma, S. Ito, H. Yano, Y. Imoto, K. Okamoto, M. Kaji, S. Okamura","doi":"10.1109/APBP.2004.1412351","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412351","url":null,"abstract":"An infrared fluorescence endoscope (IRFE) was used to evaluate several kinds of gastrointestinal lesions under indocyanine-green (ICG) administration. It may be useful as a novel diagnostic procedure for vascular lesions occurring in the gastrointestinal tract.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"120 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128060462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412340
Yen Sun, Jiunn-Wen Su, Sung-Jan Lin, S. Jee, C. Dong
Multiphoton microscopy is a three-dimensional imaging technique with a number of advantages. For example, multiphoton microscopy can image tissues up to a depth of a few hundred micrometers, at high resolution and with improved contrast. In this work, we used multiphoton microscopy in investigating the actions of the chemical enhancer oleic acid in transdermal drug delivery. Technique of generalized polarization (GP) imaging and polarization (P) imaging associate with Laurdan to monitor the lipid layer changes caused by the addition of oleic acid. Our study will help to develop more effective methodologies in the delivering of molecules across biological barriers.
{"title":"An investigation of the relationship between the transdermal drug delivery and membranes fluidity by multiphoton imaging of Laurdan","authors":"Yen Sun, Jiunn-Wen Su, Sung-Jan Lin, S. Jee, C. Dong","doi":"10.1109/APBP.2004.1412340","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412340","url":null,"abstract":"Multiphoton microscopy is a three-dimensional imaging technique with a number of advantages. For example, multiphoton microscopy can image tissues up to a depth of a few hundred micrometers, at high resolution and with improved contrast. In this work, we used multiphoton microscopy in investigating the actions of the chemical enhancer oleic acid in transdermal drug delivery. Technique of generalized polarization (GP) imaging and polarization (P) imaging associate with Laurdan to monitor the lipid layer changes caused by the addition of oleic acid. Our study will help to develop more effective methodologies in the delivering of molecules across biological barriers.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114631090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412354
Ken-Ming Guo, Shu-Fang Cheng, L. Chau, Jaw-Luen Tang
A novel class of fiber-optic biosensor that exploits the localized surface plasmon resonance of self-assembled gold colloids on the grating portion of a long-period fiber grating is proposed. When the gold colloidal surface was modified with DNP, experimental results show that the signal increases linearly with increasing concentration of the analyte, and the detection limit of the sensor for antiDNP is 3.80/spl times/10/sup -7/ M.
{"title":"Optical biosensor based on colloidal gold-modified long-period fiber grating","authors":"Ken-Ming Guo, Shu-Fang Cheng, L. Chau, Jaw-Luen Tang","doi":"10.1109/APBP.2004.1412354","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412354","url":null,"abstract":"A novel class of fiber-optic biosensor that exploits the localized surface plasmon resonance of self-assembled gold colloids on the grating portion of a long-period fiber grating is proposed. When the gold colloidal surface was modified with DNP, experimental results show that the signal increases linearly with increasing concentration of the analyte, and the detection limit of the sensor for antiDNP is 3.80/spl times/10/sup -7/ M.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130067738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412257
T. Asahi
This paper is concerned with Rayleigh scattering spectroscopy using a dark-field optical microscope for the purpose of studying optical and electronic properties of isolated single nanoparticles. Size dependent optical resonance of organic nanocrystals was demonstrated using an optical microscope setup coupled with AFM. The adsorption effects of molecules on the surface plasmon resonance spectra of individual gold nanoparticles were examined in detail and the potential application of the single-nanoparticle SPR to chemical and biological sensors is discussed.
{"title":"Rayleigh scattering microspectrosopy of individual nanoparticles","authors":"T. Asahi","doi":"10.1109/APBP.2004.1412257","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412257","url":null,"abstract":"This paper is concerned with Rayleigh scattering spectroscopy using a dark-field optical microscope for the purpose of studying optical and electronic properties of isolated single nanoparticles. Size dependent optical resonance of organic nanocrystals was demonstrated using an optical microscope setup coupled with AFM. The adsorption effects of molecules on the surface plasmon resonance spectra of individual gold nanoparticles were examined in detail and the potential application of the single-nanoparticle SPR to chemical and biological sensors is discussed.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133591508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412278
Hsin-Yi Chen, P. Hung
Retinal nerve fiber layer defect, which may present prior to visual field damage, is an important sign of primary open angle glaucoma. Early diagnosis have been emphasized in the treatment of glaucoma.
视网膜神经纤维层缺损可先于视野损害出现，是原发性开角型青光眼的重要标志。青光眼的治疗强调早期诊断。
{"title":"Clinical application of optical coherence tomography in glaucoma","authors":"Hsin-Yi Chen, P. Hung","doi":"10.1109/APBP.2004.1412278","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412278","url":null,"abstract":"Retinal nerve fiber layer defect, which may present prior to visual field damage, is an important sign of primary open angle glaucoma. Early diagnosis have been emphasized in the treatment of glaucoma.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134346207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412275
H. Xia, K. Ishii, T. Iwai
Using low-coherence dynamic light scattering (LCDLS) method, which allows us to measure the light single scattered from dense media, we investigated the hydrodynamic properties of particles. The effect of hydrodynamic interactions on diffusion of particles is studied by measuring the dependence of the diffusion coefficient on the particle concentration. The hydrodynamic radius distributions with an accuracy within 3% are obtained for dense suspensions with the volume fraction of 10 vol.% by using the CONTIN method.
{"title":"Study on hydrodynamic properties in dense media","authors":"H. Xia, K. Ishii, T. Iwai","doi":"10.1109/APBP.2004.1412275","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412275","url":null,"abstract":"Using low-coherence dynamic light scattering (LCDLS) method, which allows us to measure the light single scattered from dense media, we investigated the hydrodynamic properties of particles. The effect of hydrodynamic interactions on diffusion of particles is studied by measuring the dependence of the diffusion coefficient on the particle concentration. The hydrodynamic radius distributions with an accuracy within 3% are obtained for dense suspensions with the volume fraction of 10 vol.% by using the CONTIN method.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134313137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412280
Hsin-Ming Chen, T. Tsai, C. Chiang
Eleven cases of oral verrucous hyperplasia (OVH) and 36 cases of oral leukoplakia (OL) were treated with a topical 5-aminolevulinic acid (ALA-PDT) that was found to be very effective for OVH lesions but not for OL lesions.
{"title":"PDT for oral precancerous lesions","authors":"Hsin-Ming Chen, T. Tsai, C. Chiang","doi":"10.1109/APBP.2004.1412280","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412280","url":null,"abstract":"Eleven cases of oral verrucous hyperplasia (OVH) and 36 cases of oral leukoplakia (OL) were treated with a topical 5-aminolevulinic acid (ALA-PDT) that was found to be very effective for OVH lesions but not for OL lesions.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132626930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-12-15DOI: 10.1109/APBP.2004.1412362
C.-W. Lin, C. Lee, W. Wang, C. Lee
We reported the design and development of a dual-window SPR sensor, which is based on Ge-doped silica waveguide structure. By employing the WDM concept, a single waveguide can detect two or more kinds of samples in different ranges of wavelengths. The silica waveguides with low refractive index are good for lower SPR spectrum range in liquid. The two channels silica waveguide SPR sensors had been successfully fabricated and tested with two solutions, whose refractive indices are 1.361 and 1.418, respectively. The resultant spectrum has two resonant peaks at 626.41 nm and 751.8 nm, respectively.
{"title":"A novel cross-reference dual-window SPR sensor based on single silica optical waveguide","authors":"C.-W. Lin, C. Lee, W. Wang, C. Lee","doi":"10.1109/APBP.2004.1412362","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412362","url":null,"abstract":"We reported the design and development of a dual-window SPR sensor, which is based on Ge-doped silica waveguide structure. By employing the WDM concept, a single waveguide can detect two or more kinds of samples in different ranges of wavelengths. The silica waveguides with low refractive index are good for lower SPR spectrum range in liquid. The two channels silica waveguide SPR sensors had been successfully fabricated and tested with two solutions, whose refractive indices are 1.361 and 1.418, respectively. The resultant spectrum has two resonant peaks at 626.41 nm and 751.8 nm, respectively.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114164043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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