Pub Date : 2025-06-30DOI: 10.1016/j.npg.2025.04.002
Francesco Ferrara
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra and the accumulation of α-synuclein aggregates. Current pharmacological treatments, including levodopa and dopamine agonists, mainly offer symptomatic relief but do not modify disease progression. The heterogeneity of clinical manifestations and underlying molecular mechanisms has prompted a shift toward personalized medicine and innovative therapeutic strategies. Among emerging approaches, cell-based therapies — such as stem cell transplantation and induced pluripotent stem cells — aim to restore dopaminergic function and are under active investigation in preclinical and early clinical settings. In parallel, digital therapeutics and wearable technologies offer real-time, objective monitoring of motor and non-motor symptoms, enabling more accurate disease tracking and treatment optimization. These digital tools also facilitate remote patient management and adherence to therapy. Artificial intelligence (AI) has become increasingly integrated into PD research and care, with machine learning algorithms demonstrating high accuracy in early disease detection, symptom monitoring, and risk prediction. Notably, AI-based analyses of data from wearable sensors and digital biomarkers have identified prodromal signs of PD years before clinical diagnosis, offering promising avenues for preventive strategies. While no disease-modifying therapies are currently available, combining pharmacological treatments with advanced technologies and a deeper understanding of disease biology may pave the way for more effective and individualized interventions. The integration of AI, digital health, and cell-based therapies is a paradigm shift in the management and future treatment landscape of Parkinson's disease.
{"title":"Parkinson's disease between old drugs and new digital therapies: A pharmacological review","authors":"Francesco Ferrara","doi":"10.1016/j.npg.2025.04.002","DOIUrl":"10.1016/j.npg.2025.04.002","url":null,"abstract":"<div><div>Parkinson's disease (PD) is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra and the accumulation of α-synuclein aggregates. Current pharmacological treatments, including levodopa and dopamine agonists, mainly offer symptomatic relief but do not modify disease progression. The heterogeneity of clinical manifestations and underlying molecular mechanisms has prompted a shift toward personalized medicine and innovative therapeutic strategies. Among emerging approaches, cell-based therapies — such as stem cell transplantation and induced pluripotent stem cells — aim to restore dopaminergic function and are under active investigation in preclinical and early clinical settings. In parallel, digital therapeutics and wearable technologies offer real-time, objective monitoring of motor and non-motor symptoms, enabling more accurate disease tracking and treatment optimization. These digital tools also facilitate remote patient management and adherence to therapy. Artificial intelligence (AI) has become increasingly integrated into PD research and care, with machine learning algorithms demonstrating high accuracy in early disease detection, symptom monitoring, and risk prediction. Notably, AI-based analyses of data from wearable sensors and digital biomarkers have identified prodromal signs of PD years before clinical diagnosis, offering promising avenues for preventive strategies. While no disease-modifying therapies are currently available, combining pharmacological treatments with advanced technologies and a deeper understanding of disease biology may pave the way for more effective and individualized interventions. The integration of AI, digital health, and cell-based therapies is a paradigm shift in the management and future treatment landscape of Parkinson's disease.</div></div>","PeriodicalId":35487,"journal":{"name":"NPG Neurologie - Psychiatrie - Geriatrie","volume":"25 148","pages":"Pages 179-186"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144687336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-28DOI: 10.1016/j.npg.2025.04.003
Marie-Claire Benetti Papadacci
L’efficacité de l’art-thérapie dans l’accompagnement des patients souffrant de pathologies neurogénératives reste encore difficile à mesurer de manière standardisée, en raison du manque d’outils validés d’évaluation. La grille DATEI ou dispositif art-thérapeutique d’évaluation et d’intervention propose de combler cette lacune, sur quatre axes principaux : l’engagement artistique, l’expression émotionnelle, l’interaction sociale et les capacités cognitives. L’étude a été menée auprès de 15 patients atteints de la maladie d’Alzheimer dans le cadre d’un essai pilote recruté au Centre mémoire de l’hôpital d’Ajaccio. Les premiers résultats obtenus suggèrent une amélioration notable sur ces quatre critères. La grille DATEI semble constituer un cadre structuré permettant d’adapter les interventions en art-thérapie afin de favoriser une prise en charge plus individualisée.
The effectiveness of art therapy in supporting patients with neurodegenerative diseases remains difficult to measure in a standardized manner due to the lack of validated assessment tools. The DATEI Grid, or Art-Therapy Assessment and Intervention Device, has been developed to fill this gap, focusing on four main approaches: artistic engagement, emotional expression, social interaction, and cognitive abilities. The study was conducted with 15 patients diagnosed with Alzheimer's disease as part of a pilot trial recruiting patients at the Memory Center of Ajaccio Hospital. The first results obtained suggest a notable improvement across these four criteria. The DATEI Grid appears to provide a structured framework for adapting art therapy interventions to promote a more individualized approach to patient care.
{"title":"Création de la grille DATEI pour l’évaluation et l’intervention en art-thérapie","authors":"Marie-Claire Benetti Papadacci","doi":"10.1016/j.npg.2025.04.003","DOIUrl":"10.1016/j.npg.2025.04.003","url":null,"abstract":"<div><div>L’efficacité de l’art-thérapie dans l’accompagnement des patients souffrant de pathologies neurogénératives reste encore difficile à mesurer de manière standardisée, en raison du manque d’outils validés d’évaluation. La grille DATEI ou dispositif art-thérapeutique d’évaluation et d’intervention propose de combler cette lacune, sur quatre axes principaux : l’engagement artistique, l’expression émotionnelle, l’interaction sociale et les capacités cognitives. L’étude a été menée auprès de 15 patients atteints de la maladie d’Alzheimer dans le cadre d’un essai pilote recruté au Centre mémoire de l’hôpital d’Ajaccio. Les premiers résultats obtenus suggèrent une amélioration notable sur ces quatre critères. La grille DATEI semble constituer un cadre structuré permettant d’adapter les interventions en art-thérapie afin de favoriser une prise en charge plus individualisée.</div></div><div><div>The effectiveness of art therapy in supporting patients with neurodegenerative diseases remains difficult to measure in a standardized manner due to the lack of validated assessment tools. The DATEI Grid, or Art-Therapy Assessment and Intervention Device, has been developed to fill this gap, focusing on four main approaches: artistic engagement, emotional expression, social interaction, and cognitive abilities. The study was conducted with 15 patients diagnosed with Alzheimer's disease as part of a pilot trial recruiting patients at the Memory Center of Ajaccio Hospital. The first results obtained suggest a notable improvement across these four criteria. The DATEI Grid appears to provide a structured framework for adapting art therapy interventions to promote a more individualized approach to patient care.</div></div>","PeriodicalId":35487,"journal":{"name":"NPG Neurologie - Psychiatrie - Geriatrie","volume":"25 148","pages":"Pages 172-178"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144687328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-28DOI: 10.1016/j.npg.2025.04.001
{"title":"La place de la société civile dans la lutte contre les maltraitances doit être maintenue","authors":"","doi":"10.1016/j.npg.2025.04.001","DOIUrl":"10.1016/j.npg.2025.04.001","url":null,"abstract":"","PeriodicalId":35487,"journal":{"name":"NPG Neurologie - Psychiatrie - Geriatrie","volume":"25 147","pages":"Pages 161-162"},"PeriodicalIF":0.0,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144168828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-16DOI: 10.1016/j.npg.2025.03.001
F. Brossard
Objectif
En établissement gériatrique, nombreux sont ceux qui connaissent un sentiment de solitude. Le grand âge et la perte d’un étayage social fragilisent un soutien basé sur des liens pourtant établis de longue date. Nul doute que ce sentiment peut être alors proportionnel au désarrimage social.
Patient
Un résident octogénaire mélancolique exprime souffrir de solitude. Son accompagnement est réalisé par un psychologue clinicien sur 3 ans à fréquence d’un entretien bimensuel. La méthode se base à la fois sur la psychologie clinique d’inspiration psychanalytique kleinienne mais aussi phénoménologique. Une analyse dans l’après-coup constitue la réflexion de cet article.
Résultats
La solitude peut être vécue face à un sentiment de confrontation à de mauvais aspects de soi. L’analyse des phénomènes présentés permet de repérer une certaine angoisse d’anéantissement face à une fragilisation du Moi. En effet, différents mécanismes se mettent en place notamment le clivage et la projection. Le but étant de protéger ce qui peut réassurer et demeure fragile.
Discussion
Si la solitude peut posséder une part créative, la situation présentée montre qu’elle peut également amener une part de souffrance. Le narcissisme ouvre une piste intéressante pour continuer de s’aimer soi-même en l’absence d’un autre bien qu’il demeure plus précaire dans la mélancolie.
Conclusion
Si des facteurs sociaux peuvent expliquer la solitude, cet exemple nous enseigne qu’elle peut avoir également une origine psychique. Il convient d’en connaître les différents mécanismes afin qu’un accompagnement psychothérapique puisse prendre en compte l’angoisse et les processus qui en dérivent.
Objective
In geriatric institutions, many residents experience loneliness, often exacerbated by aging and the loss of social support, which weaken long-established ties. This loneliness frequently correlates with social disengagement.
Method
We conducted a clinical case study of a melancholic octogenarian resident experiencing loneliness. Psychological support was provided through bi-monthly interviews with a clinical psychologist over 3 years. A retrospective analysis was performed using phenomenological and clinical psychological approaches grounded in Kleinian psychoanalysis.
Results
Loneliness can emerge as individuals confront negative self-perceptions. Our analysis identified an anxiety of annihilation in response to the fragility of the Ego. In order to reassure and protect the Ego, different mechanisms are employed, notably splitting and projection.
Discussion
While solitude may hold creative potential, it often provokes suffering, as evidenced in our case study. In the absence of social connections, narcissism may serve as a means of sustaining self-
{"title":"La solitude en institution gériatrique : entre état psychique et contexte social","authors":"F. Brossard","doi":"10.1016/j.npg.2025.03.001","DOIUrl":"10.1016/j.npg.2025.03.001","url":null,"abstract":"<div><h3>Objectif</h3><div>En établissement gériatrique, nombreux sont ceux qui connaissent un sentiment de solitude. Le grand âge et la perte d’un étayage social fragilisent un soutien basé sur des liens pourtant établis de longue date. Nul doute que ce sentiment peut être alors proportionnel au désarrimage social.</div></div><div><h3>Patient</h3><div>Un résident octogénaire mélancolique exprime souffrir de solitude. Son accompagnement est réalisé par un psychologue clinicien sur 3 ans à fréquence d’un entretien bimensuel. La méthode se base à la fois sur la psychologie clinique d’inspiration psychanalytique kleinienne mais aussi phénoménologique. Une analyse dans l’après-coup constitue la réflexion de cet article.</div></div><div><h3>Résultats</h3><div>La solitude peut être vécue face à un sentiment de confrontation à de mauvais aspects de soi. L’analyse des phénomènes présentés permet de repérer une certaine angoisse d’anéantissement face à une fragilisation du Moi. En effet, différents mécanismes se mettent en place notamment le clivage et la projection. Le but étant de protéger ce qui peut réassurer et demeure fragile.</div></div><div><h3>Discussion</h3><div>Si la solitude peut posséder une part créative, la situation présentée montre qu’elle peut également amener une part de souffrance. Le narcissisme ouvre une piste intéressante pour continuer de s’aimer soi-même en l’absence d’un autre bien qu’il demeure plus précaire dans la mélancolie.</div></div><div><h3>Conclusion</h3><div>Si des facteurs sociaux peuvent expliquer la solitude, cet exemple nous enseigne qu’elle peut avoir également une origine psychique. Il convient d’en connaître les différents mécanismes afin qu’un accompagnement psychothérapique puisse prendre en compte l’angoisse et les processus qui en dérivent.</div></div><div><h3>Objective</h3><div>In geriatric institutions, many residents experience loneliness, often exacerbated by aging and the loss of social support, which weaken long-established ties. This loneliness frequently correlates with social disengagement.</div></div><div><h3>Method</h3><div>We conducted a clinical case study of a melancholic octogenarian resident experiencing loneliness. Psychological support was provided through bi-monthly interviews with a clinical psychologist over 3 years. A retrospective analysis was performed using phenomenological and clinical psychological approaches grounded in Kleinian psychoanalysis.</div></div><div><h3>Results</h3><div>Loneliness can emerge as individuals confront negative self-perceptions. Our analysis identified an anxiety of annihilation in response to the fragility of the Ego. In order to reassure and protect the Ego, different mechanisms are employed, notably splitting and projection.</div></div><div><h3>Discussion</h3><div>While solitude may hold creative potential, it often provokes suffering, as evidenced in our case study. In the absence of social connections, narcissism may serve as a means of sustaining self-","PeriodicalId":35487,"journal":{"name":"NPG Neurologie - Psychiatrie - Geriatrie","volume":"25 147","pages":"Pages 123-130"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144168823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Post-stroke cognitive impairment and dementia are major public health problems.
Objectives
Construction of a cognitive assessment tool applicable to post-stroke dementia detection in the older population and suitable for both illiterate and educated Egyptians.
Methods
The new post-stroke Ain-Shams cognitive assessment (PSACA) test was scored out of 69 points. The validity and reliability of the PSACA test were assessed on a pilot sample of 30 older participants, comparing the test with the Mini-Mental State Examination (MMSE) test. Then a cross-sectional study for the detection of dementia was conducted recruiting 120 Egyptian older post-stroke participants aged 60 years and over, from Ain-Shams University Hospital clinics.
Results
The mean age of the participants was 69.17 (± 8.03). The test proved valid and reliable (Cronbach's Alpha was 0.72). The cutoff point of the PSACA test for post-stroke dementia diagnosis was ≤ 54.5, with a sensitivity of 90% and a specificity of 78.7%.
Conclusion
The PSACA test is a valid and reliable test that can be administered to detect post-stroke dementia.
{"title":"The PSACA test: A new cognitive assessment tool for detection of post-stroke dementia in a sample of older Egyptians","authors":"S.A. Sayed , S.E. Morsy , N.N. Adly , S.A. Hamza , H.M. Tawfik","doi":"10.1016/j.npg.2025.02.001","DOIUrl":"10.1016/j.npg.2025.02.001","url":null,"abstract":"<div><h3>Background</h3><div>Post-stroke cognitive impairment and dementia are major public health problems.</div></div><div><h3>Objectives</h3><div>Construction of a cognitive assessment tool applicable to post-stroke dementia detection in the older population and suitable for both illiterate and educated Egyptians.</div></div><div><h3>Methods</h3><div>The new post-stroke Ain-Shams cognitive assessment (PSACA) test was scored out of 69 points. The validity and reliability of the PSACA test were assessed on a pilot sample of 30 older participants, comparing the test with the Mini-Mental State Examination (MMSE) test. Then a cross-sectional study for the detection of dementia was conducted recruiting 120 Egyptian older post-stroke participants aged 60<!--> <!-->years and over, from Ain-Shams University Hospital clinics.</div></div><div><h3>Results</h3><div>The mean age of the participants was 69.17 (±<!--> <!-->8.03). The test proved valid and reliable (Cronbach's Alpha was 0.72). The cutoff point of the PSACA test for post-stroke dementia diagnosis was<!--> <!-->≤<!--> <!-->54.5, with a sensitivity of 90% and a specificity of 78.7%.</div></div><div><h3>Conclusion</h3><div>The PSACA test is a valid and reliable test that can be administered to detect post-stroke dementia.</div></div>","PeriodicalId":35487,"journal":{"name":"NPG Neurologie - Psychiatrie - Geriatrie","volume":"25 147","pages":"Pages 153-160"},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144168829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-18DOI: 10.1016/j.npg.2025.01.005
S. Apeti , A. Salifou , N. Tolo , L.S.P.-W. Ouedraogo , K.E. Mossi , K. Klouvi , K. Kodjo , K.Z. Apeti , M. Coume , Y. Potchoo , K.A. Balogou
<div><h3>Objectif</h3><div>Analyser les prescriptions de psychotropes chez les patients gériatriques.</div></div><div><h3>Méthodologie</h3><div>C’est une étude rétrospective sur 150 patients d’au moins 60 ans en consultation gériatrique en médecine interne aux CHU Sylvanus Olympio et Campus et à la clinique médicale Gamesu à Lomé au Togo, du juillet 2020 à juin 2021 analysant les psychotropes.</div></div><div><h3>Résultats</h3><div>La dépression était l’affection neuropsychiatrique la plus fréquente (40,7 %). Avant consultation, 28,38 % utilisaient les antidépresseurs et 62,22 % les anxiolytiques/hypnotiques. Après consultation gériatrique, 41,3 % utilisent des antidépresseurs et 18 % les anxiolytiques/hypnotiques. Paroxétine était le psychotrope le plus prescrit (27,3 %). La prescription inappropriée représentait 87,8 % des traitements antérieurs. On notait un lien significatif entre les antidépresseurs et l’âge (60 à 75 ans, <em>p</em> <!-->=<!--> <!-->0,012), et aussi le sexe féminin (<em>p</em> <!-->=<!--> <!-->0,002) ; de même entre la polypathologie et les anxiolytiques/hypnotiques (<em>p</em> <!-->=<!--> <!-->0,028), les antipsychotiques (<em>p</em> <!-->=<!--> <!-->0,048) et, les antiparkinsoniens (<em>p</em> <!-->=<!--> <!-->0,033) ainsi qu’entre l’HTA et les anxiolytiques/hypnotiques (<em>p</em> <!-->=<!--> <!-->0,025), les antipsychotiques (<em>p</em> <!-->=<!--> <!-->0,006), les antidépresseurs (<em>p</em> <!-->=<!--> <!-->0,011).</div></div><div><h3>Conclusion</h3><div>L’usage des psychotropes est fréquent en gériatrie et nécessite une culture gériatrique des prescripteurs.</div></div><div><h3>Objective</h3><div>To analyze psychotropic medication intake among the elderly.</div></div><div><h3>Methodology</h3><div>A retrospective study on psychotropic drugs prescribed to 150 patients aged 60 and over in geriatric consultation at the internal medicine department of Sylvanus Olympio and Campus CHU and Gamesu Medical Clinic from July 2020 to June 2021.</div></div><div><h3>Results</h3><div>Depression was a common neuropsychiatric affection (40.7%). Before consultation, 28.38% of patients were on antidepressants and 62.22% on anxiolytics/hypnotics. After consultation, 41.3% were prescribed antidepressants and 18% anxiolytics/hypnotics. Paroxetine was the most frequently prescribed psychotropic drug (27.3%). Inappropriate prescriptions accounted for 87.8% of previous treatments. There was a significant link between antidepressant use and age (60–75 years, <em>P</em> <!-->=<!--> <!-->0.012), and female gender (<em>P</em> <!-->=<!--> <!-->0.002). The same link was observed between polypathology and anxiolytics/hypnotics (<em>P</em> <!-->=<!--> <!-->0.028), antipsychotics (<em>P</em> <!-->=<!--> <!-->0.048), antiparkinsonians (<em>P</em> <!-->=<!--> <!-->0.033), as well as between hypertension and anxiolytics/hypnotics (<em>P</em> <!-->=<!--> <!-->0.025), antipsychotics (<em>P</em> <!-->=<!--> <!-->0.006), antidepressants (<em>P</em> <!-->=<!--
{"title":"Utilisation des psychotropes chez les personnes âgées au Togo","authors":"S. Apeti , A. Salifou , N. Tolo , L.S.P.-W. Ouedraogo , K.E. Mossi , K. Klouvi , K. Kodjo , K.Z. Apeti , M. Coume , Y. Potchoo , K.A. Balogou","doi":"10.1016/j.npg.2025.01.005","DOIUrl":"10.1016/j.npg.2025.01.005","url":null,"abstract":"<div><h3>Objectif</h3><div>Analyser les prescriptions de psychotropes chez les patients gériatriques.</div></div><div><h3>Méthodologie</h3><div>C’est une étude rétrospective sur 150 patients d’au moins 60 ans en consultation gériatrique en médecine interne aux CHU Sylvanus Olympio et Campus et à la clinique médicale Gamesu à Lomé au Togo, du juillet 2020 à juin 2021 analysant les psychotropes.</div></div><div><h3>Résultats</h3><div>La dépression était l’affection neuropsychiatrique la plus fréquente (40,7 %). Avant consultation, 28,38 % utilisaient les antidépresseurs et 62,22 % les anxiolytiques/hypnotiques. Après consultation gériatrique, 41,3 % utilisent des antidépresseurs et 18 % les anxiolytiques/hypnotiques. Paroxétine était le psychotrope le plus prescrit (27,3 %). La prescription inappropriée représentait 87,8 % des traitements antérieurs. On notait un lien significatif entre les antidépresseurs et l’âge (60 à 75 ans, <em>p</em> <!-->=<!--> <!-->0,012), et aussi le sexe féminin (<em>p</em> <!-->=<!--> <!-->0,002) ; de même entre la polypathologie et les anxiolytiques/hypnotiques (<em>p</em> <!-->=<!--> <!-->0,028), les antipsychotiques (<em>p</em> <!-->=<!--> <!-->0,048) et, les antiparkinsoniens (<em>p</em> <!-->=<!--> <!-->0,033) ainsi qu’entre l’HTA et les anxiolytiques/hypnotiques (<em>p</em> <!-->=<!--> <!-->0,025), les antipsychotiques (<em>p</em> <!-->=<!--> <!-->0,006), les antidépresseurs (<em>p</em> <!-->=<!--> <!-->0,011).</div></div><div><h3>Conclusion</h3><div>L’usage des psychotropes est fréquent en gériatrie et nécessite une culture gériatrique des prescripteurs.</div></div><div><h3>Objective</h3><div>To analyze psychotropic medication intake among the elderly.</div></div><div><h3>Methodology</h3><div>A retrospective study on psychotropic drugs prescribed to 150 patients aged 60 and over in geriatric consultation at the internal medicine department of Sylvanus Olympio and Campus CHU and Gamesu Medical Clinic from July 2020 to June 2021.</div></div><div><h3>Results</h3><div>Depression was a common neuropsychiatric affection (40.7%). Before consultation, 28.38% of patients were on antidepressants and 62.22% on anxiolytics/hypnotics. After consultation, 41.3% were prescribed antidepressants and 18% anxiolytics/hypnotics. Paroxetine was the most frequently prescribed psychotropic drug (27.3%). Inappropriate prescriptions accounted for 87.8% of previous treatments. There was a significant link between antidepressant use and age (60–75 years, <em>P</em> <!-->=<!--> <!-->0.012), and female gender (<em>P</em> <!-->=<!--> <!-->0.002). The same link was observed between polypathology and anxiolytics/hypnotics (<em>P</em> <!-->=<!--> <!-->0.028), antipsychotics (<em>P</em> <!-->=<!--> <!-->0.048), antiparkinsonians (<em>P</em> <!-->=<!--> <!-->0.033), as well as between hypertension and anxiolytics/hypnotics (<em>P</em> <!-->=<!--> <!-->0.025), antipsychotics (<em>P</em> <!-->=<!--> <!-->0.006), antidepressants (<em>P</em> <!-->=<!--","PeriodicalId":35487,"journal":{"name":"NPG Neurologie - Psychiatrie - Geriatrie","volume":"25 146","pages":"Pages 102-108"},"PeriodicalIF":0.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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