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[Review of «Mathematical modeling of ethanol kinetics» monograph by G.V. Nedugov]. [回顾«乙醇动力学的数学建模»由G.V. Nedugov专著]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256802161
A P Ardashkin

Main concepts of "Mathematical modeling of ethanol kinetics" monograph by G.V. Nedugov were analyzed in the article covering relevance, scientific and practical significance. It has been shown that comprehensive analysis of existing and proposed by the author mathematical models for assessing ethanol kinetics presented in the article is a significant contribution to the scientific and practical base of forensic medicine. The possibilities of mathematical models' effective application as a practical solution of forensic medical tasks based on objective mathematical methods were noted. Undoubtedly, the monograph is interesting not only for forensic doctors but also for other specialists of medical and biological sphere.

本文分析了G.V. Nedugov专著《乙醇动力学数学建模》的主要概念,包括相关性、科学性和现实意义。结果表明,本文对现有的乙醇动力学数学模型和作者提出的乙醇动力学数学模型进行了综合分析,为法医学的科学和实用基础做出了重大贡献。指出了数学模型作为基于客观数学方法的法医任务的实际解决方案的有效应用的可能性。毫无疑问,这本专著不仅对法医来说很有趣,而且对医学和生物学领域的其他专家来说也很有趣。
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引用次数: 0
[Forensic medical evaluation of uncomplicated compression fractures of bodies of the thoracic and lumbar parts of the spine in children]. [儿童胸椎和腰椎椎体无并发症压缩性骨折的法医鉴定]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed2025680315
V A Akbashev, L G Aleksandrova, A K Khusainova

The article considers compression fractures of the thoracic and lumbar parts of the spine without neurological complications in children considering age features, their diagnosis by X-ray, computed tomography, magnetic resonance imaging (MRI) and ultrasound, as well as differential diagnosis with degenerative-dystrophic changes of different etiology. Routine X-ray is usually insufficient for forensic medical evaluation of uncomplicated compression fractures of the vertebral bodies without gross deformities, especially to decide the issue of the age of trauma. It is necessary to critically evaluate the established diagnosis and to analyze clinical and instrumental data, considering the completeness and accuracy of the studies to exclude overdiagnosis in the forensic examination of cases of compression fractures of the vertebral bodies. A case report demonstrating the use of MRI to determine the volume and age of trauma is presented.

本文结合年龄特征、x线、ct、MRI和超声诊断以及不同病因的退行性营养不良改变的鉴别诊断,对无神经系统并发症的儿童胸椎和腰椎压缩性骨折进行分析。对于无明显畸形的无复杂性椎体压缩性骨折的法医鉴定,尤其是确定创伤年龄的问题,常规x线通常是不够的。考虑到研究的完整性和准确性,有必要批判性地评估已建立的诊断并分析临床和仪器数据,以排除在椎体压缩性骨折病例的法医检查中的过度诊断。一个案例报告演示了使用MRI来确定创伤的体积和年龄。
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引用次数: 0
[A case of a driver's death from compression asphyxia outside of passenger vehicle]. [1例驾驶员在乘用车外因压迫性窒息死亡]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256805143
R R Kidraliev, A P Kidralieva

The article presents a case of a combined type of motor vehicle injury in the driver in the cab of passenger vehicle followed by falling out through the windshield and compression of the body between the overturned car and the ground surface with compression asphyxia development. In postmortem examination multiple incised wounds, scratches, bruises and contused wounds on the face, anterior surface of the chest, upper and lower extremities, hemorrhages in the soft tissues of occipital region of the head and back, closed multi-fragment fracture of the right radial bone in the lower third with displacement of fragments were found. Thus, there were no injuries of the visceral organs and other bones of the skeleton. Classic asphyctic signs and carmine pulmonary edema were also revealed in the corpse's examination. It was concluded based on the obtained data that the pressure force of the motor vehicle did not exceed the threshold of resistance of the bones and visceral organs in this case, and therefore did not lead to their damage, but it caused an obstacle for respiratory movements and led to death from compression asphyxia. Thus, the version of police investigation about circumstances of the motor vehicle accident was confirmed and the cause of death was established on the basis of a comprehensive assessment of the corpse's forensic examination results, analysis of investigative and operational information, data of the accident site inspection.

本文介绍了一例乘用车驾驶室驾驶员发生的混合型机动车伤害,随后驾驶员从挡风玻璃中脱落,车身在翻倒的汽车与地面之间受压,并发生压缩性窒息。尸检发现面部、胸部前表面、上肢和下肢多处切口、划伤、瘀伤和挫伤,头部和背部枕区软组织出血,右下三分之一桡骨闭合性多碎片骨折并碎片移位。因此,没有内脏器官和骨骼的其他骨骼的损伤。尸体检查还发现了典型的窒息体征和胭脂红肺水肿。根据获得的数据得出结论,在本例中,机动车的压力没有超过骨骼和内脏器官的阻力阈值,因此没有导致骨骼和内脏器官的损伤,但对呼吸运动造成障碍,导致压缩性窒息死亡。因此,警方关于机动车事故情况的调查得到了证实,并根据对尸体法医检查结果的综合评估、对调查和行动资料的分析以及事故现场检查数据确定了死亡原因。
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引用次数: 0
[On the forensic significance of cadaveric spots color in death from general hypothermia]. [关于一般体温过低死亡中尸体斑点颜色的法医意义]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256805132
A Yu Chudakov, I A Tolmachev, V V Gaivoronskaya

The forensic medical investigation of occurrence mechanisms (causes) and color spectrum of cadaveric spots in corpses of persons who were victims of general accidental hypothermia remains a relevant topic, causing many discussions in the scientific literature. Issues concerning the color, localization, degree of pronouncement and timing of cadaveric spots occurrence require careful analysis as they are important both for forensic medical practice and criminalistics and for understanding the processes developing in the human body after death. In the investigation of cadaveric spots resulting from general hypothermia, it should be considered that these spots are formed as a result of blood redistribution in tissues. This phenomenon is related to the fact that when the body temperature is lowered, there is a vasoconstriction, which contributes to the accumulation of blood in certain areas, as well as direct primary cryodestruction of erythrocytes in superficial tissues occurs. As a result of this process, spots, which can vary in color from bright red to purple depending on the degree of tissue hypoxia and conversely tissue oxygen saturation as well as time since death, are formed. According to our own observations and literature analysis, cadaveric spots in death from general hypothermia begin to occur on average 1-2 h after death coming. They become most pronounced after 6-12 h, while their maximum brightness is observed after about 24 h. The localization of cadaveric spots usually depends on the body's position and can vary: spots most commonly emerge on the back, buttocks and posterior surfaces of the extremities when laying down without changing the position. The color spectrum of cadaveric spots can change as well. Initially they may have a bright pink-red shade, which over time changes to darker tones such as purple, violet or even black, depending on the environmental impact and tissue condition. These changes may be caused by both the internal processes and influence of external factors such as ambient temperature. The study of the mechanisms of cadaveric spots formation is important for forensic medical practice, as it allows forensic medical experts to determine more accurately the time and cause of death. Understanding of how general hypothermia affects the process of thanatogenesis can help to establish legally significant facts, for example in cases involving accidents or crimes. Thus, the examination of cadaveric spots in victims of general accidental hypothermia is a complex and multifaceted process that requires careful approach and in-depth analysis. This knowledge not only contributes to a more accurate interpretation of forensic medical data, but also broadens the understanding of the pathophysiological changes that occur during cooling in the human body before death, at the time of death and after death from hypothermia.

一般意外低温受害者尸体上的尸体斑点的发生机制(原因)和颜色光谱的法医调查仍然是一个相关的话题,在科学文献中引起了许多讨论。关于尸体斑点出现的颜色、位置、明显程度和时间的问题需要仔细分析,因为它们对法医实践和犯罪学以及了解人死后身体发展的过程都很重要。在对全身体温过低导致的尸体斑点的调查中,应该考虑这些斑点是由于血液在组织中重新分布而形成的。这一现象与体温降低时血管收缩有关,血管收缩导致血液在某些部位积聚,并发生浅表组织红细胞的直接原发性冷冻破坏。这一过程的结果是,根据组织缺氧的程度和组织氧饱和度以及死亡时间的不同,形成了从鲜红色到紫色不等的斑点。根据我们自己的观察和文献分析,全身低温死亡的尸体斑点平均在死亡后1-2小时开始出现。尸体斑在6-12小时后最明显,约24小时后亮度最大。尸体斑的定位通常取决于身体的体位,并且可以变化:最常见的斑点出现在背部、臀部和四肢后表面,躺下时不改变体位。尸体斑点的颜色光谱也会发生变化。最初,它们可能是明亮的粉红色,随着时间的推移,根据环境影响和组织状况,它们会变成更暗的色调,如紫色、紫色甚至黑色。这些变化可能由内部过程和外部因素(如环境温度)的影响引起。对尸体斑点形成机制的研究对法医实践很重要,因为它使法医专家能够更准确地确定死亡时间和原因。了解一般体温过低如何影响死亡发生过程有助于确立具有法律意义的事实,例如涉及事故或犯罪的案件。因此,检查一般意外体温过低受害者的尸体斑点是一个复杂和多方面的过程,需要仔细的方法和深入的分析。这一知识不仅有助于更准确地解释法医数据,而且还扩大了对死前、死时和死后体温过低导致的人体冷却过程中发生的病理生理变化的理解。
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引用次数: 0
[Improvement of the organization of forensic medical expertise in emergencies through digital technologies]. [利用数字技术改进紧急情况下法医专业知识的组织]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed2025680615
I Yu Makarov, P V Glybochko, V N Gridin, M A Dymochka, S I Kolesnikov, E V Kriukov, I A Tolmachev, D A Sheptulin, S V Leonov, Yu I Pigolkin

The paper examines modern approaches to organizing forensic medical examinations in emergency situations involving mass casualties. It is noted that traditional organizational methods under such conditions are insufficiently effective, which necessitates the introduction of new organizational and methodological solutions. The feasibility of using digital technologies in forensic practice is substantiated, including automated registration and documentation systems, three-dimensional modeling, telemedicine, mobile technologies, and artificial intelligence algorithms. Examples of developed software systems and methodologies are presented, demonstrating improved efficiency of forensic medical examinations and enhanced interagency coordination. The implementation of these technologies contributes to the formation of a unified digital space for forensic medical data, optimizes expert procedures, and increases the evidential reliability of forensic conclusions.

该文件探讨了在涉及大规模伤亡的紧急情况下组织法医检查的现代方法。人们注意到,在这种情况下,传统的组织方法不够有效,因此需要采用新的组织和方法解决办法。在法医实践中使用数字技术的可行性得到证实,包括自动注册和文件系统、三维建模、远程医疗、移动技术和人工智能算法。介绍了已开发的软件系统和方法的实例,表明提高了法医检查的效率和加强了机构间的协调。这些技术的实施有助于形成统一的法医数据数字空间,优化专家程序,提高法医结论的证据可靠性。
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引用次数: 0
[Establishing the presence of a deformed zone of the blade point of a cutting-stitching tool by injuries to the heart]. [确定切割缝合工具的刀尖因心脏受伤而出现变形区域]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256806128
A A Devyaterikov, A I Avdeev, I V Vlasyuk

The significance of the conducted study is due to the high frequency of injuries caused by the impact of sharp objects. According to our empirical data, stab wounds to the heart account for 36% of the total number of injuries caused by stabbing and cutting instruments. The results of the study of scientific literature indicate that studies of the morphological features of stab injuries to internal organs are presented in isolated works. This study presents experimental data aimed at identifying the morphological signs of pericardial injuries caused by knives with various types of deformations in the tip area. In the course of the work, probabilities for each of the morphological signs were calculated and diagnostic coefficients were developed. The results obtained allow us to identify informative signs that have high prognostic value for determining the nature of the deformation of the tip of the traumatic object or its absence.

这项研究的意义在于,由于尖锐物体的撞击造成的伤害频率很高。根据我们的经验数据,心脏刺伤占刺伤和切割工具造成的伤害总数的36%。科学文献的研究结果表明,对内脏刺伤的形态学特征的研究在孤立的作品中提出。本研究提供了实验数据,旨在识别刀尖区不同类型变形造成的心包损伤的形态学特征。在工作过程中,计算了每种形态标志的概率,并制定了诊断系数。获得的结果使我们能够识别具有高预后价值的信息标志,以确定创伤对象尖端变形的性质或其缺失。
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引用次数: 0
[Towards understanding the fauna of buried corpses]. [了解埋葬尸体的动物群]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256801130
V L Popov, S N Lyabzina, R V Isaev

The goal: Is to describe the occurrence of the Rhizophagus parallelocollis graveyard beetle in inhumated bodies in forensic practice and to evaluate the potential for establishing an accurate date of burial based on entomological analysis of the presence of Rh. parallelocollis in the remains. Numerous accumulations of graveyard beetle fragments were found in cadavers buried at a depth of 2.0-2.5 meters in the vicinity of Smolensk in 2013. The collected materials consisted mainly of individual body parts (pronotum, head, abdomen, and elytral). The highly developed sense of smell of these beetles allows them to detect corpses and migrate to depths of several meters by freely penetrating wooden coffins and metal boxes. The highest concentration of beetles were observed in hollow structures (skulls, leather shoes). The occurrence of Rh. parallelocollis on inhumation bodies is directly correlated with the duration of time the beetles have spent at the site. The discovery of large numbers of beetle remains (more than 5.000) indicates the age of the buried material and the estimated period of burial - 1941-1945.

目的:描述在法医实践中,平行根噬菌墓地甲虫在尸体中出现的情况,并评估基于Rh存在的昆虫学分析建立准确埋葬日期的潜力。遗骸中有平行柱体。2013年,在斯摩棱斯克附近埋在2.0-2.5米深的尸体中发现了大量墓地甲虫碎片。收集的材料主要由个体身体部位(前前额、头部、腹部和鞘翅)组成。这些甲虫高度发达的嗅觉使它们能够探测尸体,并通过自由地穿透木制棺材和金属盒子,迁徙到几米深的地方。在空心结构(头骨、皮鞋)中观察到甲虫的最高浓度。Rh的出现。尸体上的平行纹与甲虫在现场停留的时间直接相关。大量甲虫遗骸的发现(超过5000个)表明了被埋材料的年龄和估计的埋葬时间- 1941-1945。
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引用次数: 0
[Application of quantitative absorption-elusion reaction for determining the group specificity of blood traces on material evidence]. 定量吸收-逃避反应在物证上测定血迹群体特异性中的应用
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256803138
A A Gusarov, E P Sabchuk, O D Yagmurov, V L Sidorov

The article shows the possibilities of improved version of quantitative absorption-elusion reaction (QAER) developed for determination of the blood traces' group specificity on material evidence when the phenomenon of antibodies block occurs. A similar technique in the form of combination of two immunological reactions, namely absorption-elusion reaction (AER) and quantitative absorption reaction (QAR), was previously used only in the performance of forensic biological examinations of discharge traces. The conducted studies have shown the high efficiency of QAER for determining the group affiliation of blood traces: out of 197 studied objects with a negative CRA result, the presence of an antigen was established in 128 objects using quantitative accounting of the absorption phase, and in the remaining 69 objects, the truth of the negative CRA result was established - the absence of a group factor.

本文介绍了改进后的定量吸收-逃避反应(QAER)方法在抗体阻滞现象发生时根据物证测定血液痕量群体特异性的可能性。一种类似的技术,以两种免疫反应,即吸收-逃避反应(AER)和定量吸收反应(QAR)的组合形式,以前仅用于法医生物学检查的排泄痕迹。所进行的研究表明,QAER在确定血液痕迹的群体隶属关系方面效率很高:在197个具有阴性CRA结果的研究对象中,通过对吸收阶段的定量计算,在128个对象中确定了抗原的存在,而在其余69个对象中,确定了阴性CRA结果的真实性-没有群体因素。
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引用次数: 0
[Mathematical programming in assessment of the postmortem interval under conditions of linearly varying external temperature]. [在外部温度线性变化的条件下评估死后时间间隔的数学规划]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256804134
V G Nedugov, G V Nedugov

Objective: To develop and implement a method for determining the postmortem interval and the marginal errors of its estimates under conditions of linearly varying external temperature in the format of an online application.

Material and methods: A computer-assissted numerical search for the absolute minimum point of the objective function obtained from a system of nonlinear equations reflecting the results of double rectal or cranioencephalic thermometry of a corpse under conditions of linearly varying external temperature was carried out. The search algorithm was generalized to possible marginal errors in measuring the initial indicators of temperature and time. The code of the online program was compiled in Python 3.

Results: A method based on an iterative nonlinear optimization algorithm for determining the postmortem interval in linearly varying external temperature has been developed. It allows using double rectal or cranioencephalic thermometry to consider the uniqueness of the corpse's cooling conditions using double rectal or cranioencephalic thermometry, as well as to find the degree of uncertainty of computational estimates of the method caused by the impact of measurement errors. The method is implemented in the format of the Warm Bodies Z 2 online application.

Conclusion: The developed method and the online application implementing it are recommended to establish the postmortem interval.

目的:建立并实施一种在外部温度线性变化条件下确定死后间隔及其估计边际误差的在线应用方法。材料和方法:利用计算机辅助数值搜索,从反映在外部温度线性变化条件下尸体双直肠或颅脑测温结果的非线性方程组中得到目标函数的绝对极小点。将搜索算法推广到测量温度和时间初始指标时可能出现的边际误差。在线程序的代码是用Python 3编译的。结果:建立了一种基于迭代非线性优化算法的确定外部温度线性变化下死后时间间隔的方法。它允许使用双直肠或颅脑测温来考虑使用双直肠或颅脑测温的尸体冷却条件的独特性,以及发现由于测量误差的影响而导致的方法计算估计的不确定程度。该方法以Warm Bodies z2在线应用程序的格式实现。结论:推荐采用开发的方法和在线应用程序建立尸检间隔。
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引用次数: 0
[Development of conditions for determination of imidazole derivatives in the blood using chromatography-mass spectrometry]. 色谱-质谱联用法测定血液中咪唑衍生物的条件研究
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256803132
S S Kataev, O N Dvorskaya, A V Vasilenko, E A Krylova

The problem of clonidine, moxonidine, tizanidine determination in forensic studies of biological objects remains due to low therapeutic and toxic concentrations in biological material, that creates certain difficulties in detecting the use of these substances. The study objective is to develop chromato-mass-spectrometry conditions for imidazole derivatives determination in the blood for purposes of forensic chemical and chemical toxicological analysis. The conditions for reliable clonidine, moxonidine, tizanidine identification in the blood using solid-phase extraction and gas chromatography with mass-spectrometry detection are selected. Gas chromatographic and mass spectrometric characteristics of clonidine, moxonidine, tizanidine derivatives which can be used for the purposes of forensic chemical and chemical toxicological analysis were studied.

生物物体法医研究中测定可乐定、莫onidine、tizanidine的问题仍然存在,因为生物材料中的治疗浓度和毒性浓度很低,这在检测这些物质的使用方面造成了某些困难。研究目的是建立用于法医化学和化学毒理学分析的血液中咪唑衍生物的色谱-质谱分析条件。选择了固相萃取-气相色谱-质谱法测定血液中可乐定、莫onidine、tizanidine的可靠条件。研究了可用于法医化学和化学毒理学分析的可乐定、莫克隆定、替扎尼定衍生物的气相色谱和质谱特征。
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引用次数: 0
期刊
Sudebno-Meditsinskaya Ekspertisa
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