Sudebno-Meditsinskaya Ekspertisa最新文献

The study objective was to describe the formation of forensic microbiological examination as an analysis of a new type, defined as the detection and registration of reliably measured environmental and physiological changes within the microbial community of corpse in order to substantiate the possibility of using microbiological parameters to establish the prescription of death coming. It has been determined that the knowledge of the patterns of interaction of a human and his corpse with endogenous and exogenous flora provides the basis for solving a number of traditional and new application-oriented expert tasks and the allocation of such a variety of forensic examination as forensic microbiological examination. Endogenous and exogenous human flora and its interaction with living and dead biological tissues are the objects of this kind of examination, and the dynamic patterns of such interaction are the subject of study. One of the initial relevant tasks of forensic microbiological examination consists in development of methods, adequate for the expert task to be solved, choice of the research «target», «models» for comparative analysis and medium, adequate for task in hand, as well as certification of these methods and standardization of assessment criteria for the obtained results.

Objective: To study emergence mechanism, physical nature, pattern of intravital and postmortem changes of biological and non-biological objects originated in the period from 1550 to 1918 yr. using traditional X-ray and X-ray computed tomography.

Material and methods: The relics of Saint Macarius the Roman of Novgorod, the remains of the First Reverend of the Resurrection Novodevichy Convent in Saint Petersburg Mother Superior Theophania, damages on the chair leg on which Tsesarevich Alexey sat during the shooting of Russian Emperor Nicholas II, his family and entourage in 1918 in Yekaterinburg were stidued.

Results and conclusion: The application of highly informative methods of traditional X-ray and X-ray computed tomography of biological and non-biological objects showed their high informativity and allowed to correctly interpret the emergence mechanism, physical nature, pattern of intravital and postmortem changes of skeleton bones and historical artefact (chair legs) originated long ago. The necessity of special professional training and advanced training of experts in forensic radiology to prevent possible diagnostic and expert errors has been substantiated.

Objective: To examine the applicability of IHC staining method: with TGF-β1 antibodies (serial examination, statistically processed results) and with mast cell tryptase antibodies for injuries vitality determination.

Material and methods: 261 skin autopsy samples with mechanical injuries from 29 persons were divided to 3 groups (87 in each group): vital injuries, postmortal injuries, control non-injured samples. A routine histological examination using standard H&E stain and IHC both with TGF-β1 and mast cells tryptase antibodies was performed.

Results and conclusion: The positive TGF-β1 staining (score 2-3) was found in keratinocytes in vitally injured skin and the negative or weak one (score 0-1) was found in control postmortally injured and non-injured samples. Additionally, dermal TGF-β1 expression was found in some vitally injured skin samples. The difference between vitally injured skin and control samples was statistically significant (p<0.05). No significant difference of dermal mast cells density in groups 1, 2, 3 was found.

Objective: To analyze the contribution of alcohol and drug intoxication to fatal occupational injuries and sudden death at the workplace in Moscow.

Material and methods: A number of death cases of various organizations' employees equal 357 in Moscow in 2023 were investigated. The mean age of the deceased was 48.29±13.9 years, 92.4% of them were men.

Results: Ethanol in blood has been determined in 15% of the deceased. Narcotic drugs and psychotropic medications have been found in 6.7% of cases. Signs of chronic intoxication have been established in 16.5% of the deceased. Chronic intoxication accompanied or aggravated the course of 70% of cardiomyopathies. The proportion of deceased in an accident at an industry or construction site equal 23.9%, as well as ¹/₂ of the deceased in an accident on the street and in a residential building were impaired by alcohol.

Conclusion: The study of the contribution of alcohol and drug consumption to occupational mortality will allow to plan measures for reducing the mortality of working-age population.

One of the main tasks in expertise of living persons is to determine the harm caused to human health. According to the regulations, only harm to human health caused by an injury and causally related with it is taken into account in the forensic examination of a living person. The establishment of a causal link allows to assess correctly the harm severity caused to human health. In this respect, the study of the effect of biological damaging factor on human body (cause) and the result of this interaction (effect) is a new step in modern science. The article presents the analysis of data from the reports of the Russian Reference Center on monitoring of enteric infection agents for 2016-2021; the results of examinations of subjects who suffered from acute enteric infections for 2018-2019 to study causal links in forensic medicine in cases of acute intestinal infections.

The conducted research is aimed at correcting the method of graphic reconstruction of the appearance based on the skull. The method is widely used in both anthropology and criminology. The Forensic Center of Ministry of Internal Affairs of Russia was sent the skulls for which there were lifetime photographs. The restoration of the appearance in the form of graphic reconstructions was carried out by students who completed the course of Anthropological reconstruction at the RSUH, under the guidance of Prof., head of the Laboratory E.V. Veselovskaya. Strictly after the restoration of the appearance was completed, lifetime photos were provided, on the basis of which the degree of similarity of the reconstruction with the original was assessed. The purpose of the experiment is to correct the method of graphic reconstruction of the appearance based on the skull and supplement it with new details. Anthropologists carried out gender and age determination of individuals for a more accurate representation of appearance. Based on the results of comparing lifetime photographic images with the performed reconstructions, it can bed that their overall satisfactory level of compliance is sufficient for correct identification. However, a number of inaccuracies have been identified. As a result, areas of the face have been identified that require further refinement of the method of anthropological reconstruction. So, the thickness, and especially the shape, of the lips turned out to be an unresolved problem. The size of the iris is an important physiognomic feature. It is recommended to clarify the definition of the skull of the lifetime physiognomic height of the face, the width of the nose and the distance between the nasolabial folds.

The article presents an experience of organization and production of comprehensive forensic expertises in the framework of arbitration proceeding on claims of medical organization to insurance medical companies concerning the amount of payment for the rendered health care in the field of «ophthalmology» with patients' admission to round-the-clock inpatient hospital. The methodology and algorithm of forensic expertise production after earlier conducted examinations of health care quality on case materials and original medical records of hospital patients are provided.

The study aimed to analyze the literature data on postmortem changes in the brain and their use to determine the time since death. The earliest manifestations of brain cell autolysis are detected by electron microscopy (15-20 minutes after death). The longer the postmortem period, the more morphofunctional changes in the brain are revealed by histological, histochemical, and immunohistochemical studies. The pronouncement of postmortem changes varies in different brain divisions and structural elements. Postmortem scanning is the most efficient way to visualize postmortem hypostases in the brain. Brain tissue autolysis development reduces the pronouncement of grooves and convolutions, as well as CT density and contrast of structures on MR images.

Objective: Determination of the diffusion regularities of ethanol in nonencapsulated subdural hematomas.

Material and methods: The finite-element modelling of the ethanol's concentration field for the non-lethal nonencapsulated subdural hematoma using the ELCUT 6.5 application was carried out.

Results: A two-dimensional finite-element concentration field model of a low volume subdural hematoma, taking into account the different boundary conditions of ethanol diffusion, has been developed. It has been proven that the diffusion rate of ethanol is determined by the impact of its initial concentration field, the level of ethanolemia, the geometry of hematoma, as well as the diffusion properties of bounding with hematoma tissues. The possibility of ethanol diffusion in the content of a nonalcoholic hematoma from bounding tissues was shown. The central region of hematoma has been found to have the highest ethanol concentration stability. If the diffusion's boundary conditions are not identical, the indicated area shifts to the surface of hematoma with a lower density of diffusion's flow.

Conclusion: It is recommended to interpret the postmortem concentration of ethanol in the most diffusion-resistant region of hematoma as the minimum limit of ethanolemia during the hematoma formation.

Quantitative determination of ethyl glucuronide (EtG) in different biological objects in recent years has been positioned as one of the most reliable biomarkers of unconditional alcohol consumption. The aim of the study is to summarize the analytical methods of alcohol consumption testing with the use of EtG currently available in domestic and foreign literature and to present a schematic overview of possible errors in reproducibility and interpretation of research on EtG results, which may limit their use in forensic medical practice. The main objective is to increase the reliability and validity of EtG as a marker of ethanol consumption.