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[The role of primary forensic data in the context of statistical reporting on suicidal mortality]. [初级法医数据在自杀死亡率统计报告中的作用]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256806115
E N Savenkova, A A Efimov, D G Levin, K A Raykova, G R Kolokolov

The purpose of the study is to determine the importance of primary forensic medical data in the formation of statistical reporting on suicidal mortality using the example of a comparative analysis of hangings encoded as suicides and as injuries with uncertain intentions.

Material and methods: A retrospective analysis of the data on medical death certificates of victims of hangings in the Saratov region for the ten-year period from 2014 to 2023 was carried out.

Results and conclusion: The established dynamics of the progressive increase in hangings encoded as injuries with uncertain intentions (IUI), the uniformity of samples of hangings-suicides and hangings-IUI with a doubtful probability of any other kind of death by hanging, except suicide, allow us to speak about the underestimation of the suicide rate. The reason for this can be considered the established procedure for registering the type of death in primary forensic medical documentation, according to which, in the absence of information about the type of death from law enforcement agencies, the expert is forced to classify these cases into a group of injuries with uncertain intentions, namely, this information is the basis for the formation of statistical reporting on suicidal mortality.

这项研究的目的是确定初级法医数据在编制自杀死亡率统计报告中的重要性,并举例比较分析了被编码为自杀和被编码为意图不确定的伤害的上吊事件。材料和方法:对2014年至2023年十年间萨拉托夫地区绞刑受害者医学死亡证明数据进行了回顾性分析。结果和结论:已确立的以不确定意图伤害(IUI)形式出现的上吊案件逐渐增加的动态,上吊-自杀和除自杀外任何其他形式的上吊死亡的可疑概率的上吊-IUI样本的一致性,允许我们谈论对自杀率的低估。其原因可以认为是在初级法医文件中登记死亡类型的既定程序,根据该程序,在执法机构没有关于死亡类型的信息的情况下,专家被迫将这些案件归类为一组意图不确定的伤害,即,这些信息是形成自杀死亡率统计报告的基础。
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引用次数: 0
[Evaluation of VEGF-A, SP-D and MUC-1 expression in poisoning with baclofen and its combination with ethanol]. [巴氯芬中毒及与乙醇联用后VEGF-A、SP-D和MUC-1表达的评价]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256802145
O L Romanova, M L Blagonravov, P G Dzhuvalyakov, V I Torshin, E Kh Barinov, E A Lukyanova, M A Kislov

Objective: To detect MUC-1, VEGF-A, SP-D expression in lungs of rats at different times after the administration of baclofen and its combination with ethanol.

Results: An increased MUC-1 expression has been noted in presence of the administration of baclofen and its combination with ethanol. MUC-1 caused an enhancement of VEGF-A expression under hypoxia, that has been also observed in all experimental groups. SP-D expression was increased in all experimental groups.

Conclusions: Understanding of the processes that occur in lungs of animals in administration of baclofen and its combination with ethanol is necessary to develop effective treatment measures for cases of non-fatal poisoning in human by this substance, and it will be useful in determining the immediate cause of death in the case of fatal poisoning.

目的:检测巴氯芬给药及与乙醇联用后不同时间大鼠肺组织中MUC-1、VEGF-A、SP-D的表达。结果:在巴氯芬及与乙醇联合使用的情况下,muc1表达增加。MUC-1引起缺氧条件下VEGF-A表达的增强,在所有实验组中也观察到这一点。各实验组SP-D表达均升高。结论:了解巴氯芬给药及与乙醇联用对动物肺部的影响过程,对制定有效的治疗措施、确定致死性中毒病例的直接死亡原因具有重要意义。
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引用次数: 0
[On the possibility of establishing postmortem interval of human by examining the electrical conductivity of the knee joints' synovial fluid]. [通过检查膝关节滑液的电导率来确定人死后时间间隔的可能性]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256804121
A A Khalikov, A Yu Vavilov, V V Agzamov, A R Pozdeev, K O Kuznetsov

Objective: To study the electrical conductivity of the knee joints' synovial fluid of human's corpse for assessment of the possibility of its application as criterion of forensic medical diagnosis of postmortem interval.

Material and methods: The work was carried out on practical forensic medical material on the basis of the Bureau of Forensic Medical Expertise in the Republic of Bashkortostan. During the study, 103 corpses of both sexes, different ages who died from various causes were investigated. Synovial fluid of the knee joints from corpses in a state of putrefactive biotransformation of varying degrees of severity was used as the study subject. Measurements of the electrical conductivity value were carried out by conductometry using a calibrated cuvette and AKIP-6109 RLC-meter.

Results: It has been established during the study that low frequencies of electric current of 0.1 and 1 kHz are the most informative for achieving the work objective. Polynomials of the 2nd degree, establishing a relationship between the duration of the postmortem period and the synovial fluid's electrical conductivity value for each frequency of electric current with significance of approximation more than 0.95% at p<0.01, are developed, thar indicates the significance of the presented mathematical models.

Conclusion: It is promising to carry out further research in this direction with obtainment of formulas applicable for the mathematical calculation of the human's postmortem interval.

目的:研究人尸体膝关节滑液的电导率,探讨其作为死后间隙法医学诊断标准的可行性。材料和方法:这项工作是根据巴什科尔托斯坦共和国法医专家局的实际法医材料开展的。在研究过程中,研究人员调查了103具死于各种原因的男女、不同年龄的尸体。以不同严重程度的腐殖生物转化尸体的膝关节滑液为研究对象。电导率值的测量通过电导率法进行,使用校准的比色皿和AKIP-6109 RLC-meter。结果:在研究过程中确定了0.1和1khz的低频电流对实现工作目标的信息量最大。2次多项式,建立了死后时间与滑液在各电流频率下的电导率值之间的关系,在p处的近似意义大于0.95%。结论:在这一方向上开展进一步的研究是有希望的,得到了适用于人体死后时间数学计算的公式。
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引用次数: 0
[Analysis of dissertations on forensic medicine devoted to medical errors in cases of improper healthcare delivery over a 15-year period (2009-2023)]. [关于15年(2009-2023年)医疗服务不当案例中医疗差错的法医学论文分析]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256803157
O D Yagmurov, V A Koryakina, V A Fetisov

Results of dissertational researches and scientific researches are traditionally referred to the main sources for improving the quality and level of forensic medical examinations.

Objective: To analyze the results of dissertational researches, completed by degree candidates in the «Forensic Medicine» specialty over a 15-year period (2009-2023), devoted to the analysis of medical errors in cases of improper healthcare delivery.

Material and methods: An analysis of 16 works (4 doctoral and 12 PhD dissertations), published on the official websites of medical universities and the Russian Center of Forensic Medical Expertise, was done. Sampling methods of bibliometric and scientometric analyses were used.

Results: Over a 15-year period, all authors published 379 articles, of which 21 (5.5%) were published in the «Forensic Medical Expertise» journal, 27 (7.1%) - in the «Medical Expertise and Law» journal, the overwhelming majority of articles were published in various medical subject collections, materials of research and practice conferences, congresses, including in 49 peer-reviewed medical journals recommended by the State Commission for Academic Degrees and Titles of the Ministry of Education and Science of the Russian Federation.

Conclusion: Expert panel evidences on the «medical» cases indicate the need to expand and further develop joint scientific studies in such clinical disciplines as: «obstetrics and gynecology», «anesthesiology and resuscitation», «pediatric surgery», «oncology», «neonatology», «cardiology», «dentistry», «maxillofacial surgery», etc.

论文研究和科学研究成果历来被认为是提高法医鉴定质量和水平的主要来源。目的:分析15年间(2009-2023年)法医学专业学位候选人完成的论文研究结果,这些论文致力于分析医疗服务不当造成的医疗差错。材料和方法:对发表在医科大学和俄罗斯法医鉴定中心官方网站上的16部作品(4篇博士论文和12篇博士论文)进行分析。采用文献计量学和科学计量学分析的抽样方法。结果:在15年期间,所有作者发表了379篇文章,其中21篇(5.5%)发表在《法医专业知识》杂志上,27篇(7.1%)发表在《医学专业知识与法律》杂志上,绝大多数文章发表在各种医学主题文集、研究和实践会议、大会的材料中,包括在俄罗斯联邦教育和科学部国家学位和职称委员会推荐的49份同行评议医学期刊上发表。结论:专家小组关于“医学”案例的证据表明,有必要扩大和进一步发展临床学科的联合科学研究,如:“妇产科”、“麻醉学和复苏”、“儿科外科”、“肿瘤学”、“新生儿学”、“心脏病学”、“牙科”、“颌面外科”等。
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引用次数: 0
[Rare variant of the trajectory of pedestrian's body moving on the roof of passenger compartment as a result of collision]. [由于碰撞导致行人身体在乘客舱顶部移动的罕见轨迹]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256805121
I N Ivanov, I E Loban, G N Batyshev

Frontal collision of a passenger car with a pedestrian in the vertical position can end by throwing the victim's body on the car body without subsequent falling onto the road. In such cases holes on the windscreen and dents on the roof of the compartment are found. Injuries to the lower extremities, head and chest are common for victims. The article describes 3 cases of collision between the car and pedestrian at a speed above 60 km/h. All the victims died at the accident scene. The bodies of two pedestrians were found on the body of vehicles.

乘用车与垂直位置的行人正面碰撞可以将受害者的身体抛到车身上,而不会随后掉落到道路上。在这种情况下,挡风玻璃上的洞和车厢顶部的凹痕被发现。下肢、头部和胸部受伤对受害者来说很常见。这篇文章描述了3起车速超过60公里/小时的汽车与行人相撞的案例。所有的受害者都死在事故现场。在车辆上发现了两具行人的尸体。
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引用次数: 0
[Features of visualization and interpretation of characteristics of firearms projectiles and damage to non-biological simulators of the human body during multispiral X-ray computed tomography with an extended Hounsfield scale]. [扩展Hounsfield尺度的多螺旋x射线计算机断层扫描过程中火器弹丸特征的可视化和解释特征以及对人体非生物模拟器的损伤]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256806120
A V Kovalev, I Yu Makarov, A V Mishchenko, E V Kondratyev, V B Stragis

Objective: To study the features of visualization and interpretation of significant characteristics of gunshot projectiles and gunshot injuries to non-biological simulators of the human body when performing MSCT with an extended Hounsfield X-ray density scale.

Material and methods: The physical, chemical, forensic and criminalistic characteristics of the firearm projectile and firearm injuries to non-biological imitators of the human body (blocks of sculptural plasticine) were studied. The shots were fired from a smooth-bore long-barreled 12-gauge IZH-58MA hunting rifle using cartridges with solid metal bullets made of lead alloy.

Results and conclusion: The application of the Hounsfield densitometric scale expansion method demonstrated its high information content and allowed to reliably establish the physical and chemical characteristics of a firearm projectile, conduct differential diagnostics of metallic and non-metallic foreign deposits in the area of firearm injuries, and reduce and completely suppress metallic artifacts in the images of the objects under study. It was found that the shift of density windows towards increasing the values of densitometric characteristics in Hounsfield units (HU) led to the formation of image artifacts simulating a bullet shell that did not actually exist. In order to avoid gross expert errors, the identified patterns should be taken into account when establishing the design details of firearms projectiles, when a shell-less (all-metal) firearm projectile can be mistakenly interpreted as a shell-type.

目的:研究扩展Hounsfield x射线密度标度MSCT对人体非生物模拟器射击弹丸和射击损伤重要特征的可视化和解释特点。材料和方法:研究了火器弹丸的物理、化学、法医和犯罪特性以及火器对人体非生物仿制品(塑泥块)的伤害。这些子弹是用12口径IZH-58MA猎枪发射的,使用的是铅合金实心金属子弹。结果与结论:Hounsfield密度尺度展开法具有较高的信息量,可以可靠地建立火器弹丸的物理和化学特征,对火器损伤区域的金属和非金属异物进行鉴别诊断,减少和完全抑制研究对象图像中的金属伪影。研究发现,密度窗向增加Hounsfield单元(HU)中密度特性值的转变导致了模拟弹壳的图像伪影的形成,而这些伪影实际上并不存在。当无壳(全金属)火器弹丸可能被错误地解释为弹型时,在确定火器弹丸的设计细节时,应考虑已识别的图案,以避免严重的专家错误。
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引用次数: 0
[Fatal non-thrombotic pulmonary embolism in penis enlargement with injections of hyaluronic acid-based drugs]. 【注射透明质酸类药物引起阴茎增大致死性非血栓性肺栓塞】。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256801159
S V Shigeev, Yu E Morozov, D V Gornostaev, O A Uspekhova

Hyaluronic acid is widely used as an injectable dermal filler in medicine, especially in plastic surgery and cosmetology, due to its biocompatibility and non-immunogenicity. However, these manipulations can cause complications, the most threatening of which is non-thrombotic pulmonary embolism. The article presents a not previously described case of this complication development in a 56-year-old man who underwent penis enlargement with unknown hyaluronic acid-based drug. He complained of general health problems, shortness of breath, sweating, weakness, nausea, tremor in the limbs, and had to seek medical attention on the day of intervention. The patient died next morning. A post-injection damage on the glans penis has been revealed in forensic autopsy, a large accumulation of foreign substance with jelly-like consistency has been found in the area of the root of penis, that was confirmed by histological study. The gel has been also found in the lumina of numerous vessels of the lung of different diameter. Spectrographic analysis established the uniformity of foreign substance from the soft tissues of the root of penis and lung vessels, and also allowed to identify it as hyaluronic acid or hyaluronic acid sodium salt. The objective of this article is to inform a wide forensic audience about the possibility of developing fatal non-thrombotic pulmonary embolism associated with hyaluronic acid injections.

透明质酸因其生物相容性和非免疫原性,被广泛应用于医学领域,尤其是整形外科和美容外科,作为一种可注射的皮肤填充剂。然而,这些操作可能会引起并发症,其中最具威胁性的是非血栓性肺栓塞。本文介绍了一例以前未曾描述过的并发症病例,该病例发生在一名 56 岁的男子身上,他使用了未知的透明质酸药物进行了阴茎增大手术。他主诉全身不适、气短、出汗、虚弱、恶心、四肢震颤,不得不在手术当天就医。第二天早上,患者死亡。法医尸检显示,注射后阴茎龟头受损,在阴茎根部区域发现大量果冻状异物,组织学研究证实了这一点。在肺部许多不同直径的血管管腔中也发现了这种凝胶。光谱分析确定了阴茎根部和肺部血管软组织中异物的均匀性,并确定其为透明质酸或透明质酸钠。本文旨在让广大法医了解注射透明质酸可能导致致命的非血栓性肺栓塞。
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引用次数: 0
[Sudden infant death syndrome: diagnostic problems, study algorithm]. [婴儿猝死综合征:诊断问题,研究算法]
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed2025680215
S N Moskovsky, E K Emelyanova, D V Listkova

«Sudden infant death syndrome» (SIDS) term unifies cases of non-violent, unexpectedly occurred death of a child under one year of age in the absence of objective data explaining the causes of death, history of disease and postmortem examination.

Objective: To identify the diagnostic criteria allowing to determine the immediate cause of death in SIDS.

Material and methods: We analyzed data on 64 cases of sudden deaths of infants under 1 year of age between 2016 and 2023. All cases of sudden death) were subjected to forensic medical examination arbitrarily for the purpose of excluding violent cause of death (trauma, poisoning). Judicial committee workers requested and preliminarily studied in detail the medical records. Standards of forensic medical examination, established by regulatory order (federal laws and orders) were applied in the corpse's examination. Exclusion group included cases with confirmed chronic or congenital diseases, as well as cases of violent deaths.

Results: The use of an established postmortem examination algorithm and an international standardized autopsy protocol significantly increases the number of identified causes of death, while reducing the frequency of SIDS diagnoses, that in turn allows to improve the quality of health care system work worldwide.

Conclusion: It is necessary to develop and implement analogue of used abroad algorithm in the practice of domestic forensic medical experts and pathologists, that will allow to reveal the most frequent causes of death of children, draw attention of medical staff to them and, as a consequence, improve the quality of life-time diagnosis and contribute to the reduction of infant mortality.

“婴儿猝死综合症”一词是指在缺乏解释死亡原因、病史和尸检的客观数据的情况下,一岁以下儿童意外发生的非暴力死亡。目的:探讨确定小岛屿发展中国家直接死亡原因的诊断标准。材料与方法:我们分析了2016年至2023年间64例1岁以下婴儿猝死的数据。为了排除暴力致死原因(创伤、中毒),对所有猝死案件进行了任意的法医检查。审判委员会工作人员询问并初步详细研究了病历。对尸体的检查采用了监管命令(联邦法律和命令)规定的法医检查标准。排除组包括确诊的慢性或先天性疾病病例,以及暴力死亡病例。结果:使用已建立的尸检算法和国际标准化尸检方案显著增加了确定的死亡原因数量,同时减少了小岛屿发展中国家诊断的频率,从而提高了全球卫生保健系统的工作质量。结论:有必要在国内法医专家和病理学家的实践中开发和实施国外常用算法的模拟,从而揭示儿童最常见的死亡原因,引起医务人员的注意,从而提高终身诊断的质量,有助于降低婴儿死亡率。
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引用次数: 0
[Determination of tissular and species membership of hyaline cartilage microparticles by forensic cytology and enzyme-linked immunosorbent assay methods]. [用法医细胞学和酶联免疫吸附测定法测定透明软骨微粒的组织和种类]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256802121
A A Gusarov, V L Sidorov, N E Surikova, O D Yagmurov

The article presents the results of hyaline cartilage microparticles study by forensic cytology and quantitative enzyme-linked immunosorbent assay. Hyaline cartilage cells' polymorphism was demonstrated as a result of the performed forensic cytological study. The high sensitivity of method was confirmed, the indicators of optic density and total IgG concentration were determined, as well as the optimal values of minimal and maximal calibration samples were identified using enzyme-linked immunosorbent assay. The obtained data can be used by experts of forensic units when determining tissular and species membership of hyaline cartilage microparticles by forensic cytology and enzyme-linked immunosorbent assay methods.

本文介绍了法医学细胞学和定量酶联免疫吸附法对透明软骨微粒的研究结果。透明软骨细胞的多态性是法医细胞学研究的结果。验证了该方法的高灵敏度,测定了光密度和总IgG浓度指标,并采用酶联免疫吸附法确定了最小和最大校准样品的最佳值。获得的数据可由法医单位的专家使用法医细胞学和酶联免疫吸附测定方法确定透明软骨微粒的组织和物种成员。
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引用次数: 0
[Method of linear calibration function control according to GOST R ISO 11095-2007 for measuring the mass concentration of ethanol]. [根据 GOST R ISO 11095-2007 测量乙醇质量浓度的线性校准函数控制方法]。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256801143
M S Zatyamina, L A Smirnova, O V Ostrovskij, D V Kuznetsov

Objective: Implementation of the control method to validate previously obtained calibration functions according to GOST R ISO 11095-2007 using Reference Materials (RM): standard RMs - aqueous solutions of ethanol, produced and certified by the organization, and internal RMs - aqueous solutions of ethanol in different concentrations, developed by the user for internal use.

Material and methods: We applied the control method in accordance with the National Standard of the Russian Federation GOST R ISO 11095-2007 using the standard and internal RMs - aqueous ethanol solutions in different concentrations. Measurements were performed for two subranges of ethanol concentrations on standard and internal RMs in accordance with the certified method.

Results and conclusion: Control charts based on experimental data confirmed that the system was in a controlled state, and the calibration function required no updates on Day 7. No studied values fell outside the upper and lower control limits on the control charts. The uncertainty of the transformed values was assessed during the calibration function validation.

目标:根据 GOST R ISO 11095-2007 使用标准物质(RM)实施控制方法以验证之前获得的校准函数:标准 RM - 由组织生产和认证的乙醇水溶液,以及内部 RM - 由用户开发供内部使用的不同浓度的乙醇水溶液:我们根据俄罗斯联邦国家标准 GOST R ISO 11095-2007 使用标准和内部 RM(不同浓度的乙醇水溶液)进行了控制方法。根据认证方法对标准和内部 RM 的两个乙醇浓度子范围进行了测量:基于实验数据的控制图证实系统处于受控状态,校准功能在第 7 天无需更新。没有研究值超出控制图上的控制上限和下限。在校准功能验证期间,对转换值的不确定性进行了评估。
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引用次数: 0
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Sudebno-Meditsinskaya Ekspertisa
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