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[Diagnostic criteria of death cause from low temperature in air and water established by traditional expert examination methods]. [传统专家检查方法确定的空气和水中低温导致死亡的诊断标准]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/sudmed20246703129
A Yu Chudakov, A P Bozhchenko, Yu A Khrustaleva, I A Tolmachev, V V Gayvoronskaya

Death from general hypothermia is one of the leading causes in the structure of violent death in the Russian Federation.

Objective: To clarify and supplement the complex of differential diagnostic macro- and microscopic signs of a fatal acute general cold trauma received when person is in the air and water.

Material and methods: The conclusions of forensic medical experts on the bodies of people who died from hypothermia in the air and in water (by 150 observations) were analyzed. Methods of descriptive statistics, calculation of the frequency ratio of signs' occurrence were used.

Results: The article provides quantitative assessment of occurrence (detection) rate of diagnostically significant signs established with the help of traditional methods of expert examination. A new classification of diagnostic death signs from hypothermia taking into account their differential diagnostic significance and reflecting the conditions of a person's stay in the air and water in the pre-mortem and post-mortem periods, as well as terminal period mechanisms is proposed.

Conclusion: The established complexes of signs provide an objective basis for determining death cause in non-obvious conditions when cold exposure is expected to be one of the most damaging factors.

在俄罗斯联邦,全身体温过低导致的死亡是暴力死亡的主要原因之一:材料和方法:法医专家对在空气中和水中因体温过低死亡的尸体进行了研究:分析了法医专家对在空气中和水中因体温过低而死亡者尸体的结论(150 例观察结果)。采用了描述性统计、计算体征发生频率比等方法:文章对借助传统专家检查方法确定的具有诊断意义的体征的出现(检测)率进行了定量评估。结果:文章对借助传统专家检查方法建立的具有诊断意义的体征的发生(检出)率进行了量化评估。考虑到体征的不同诊断意义,并反映了人在死前和死后的空气和水中停留的条件以及临终阶段的机制,提出了低体温症死亡诊断体征的新分类:结论:当寒冷暴露被认为是最有害的因素之一时,已建立的体征复合体为在非明显条件下确定死因提供了客观依据。
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引用次数: 0
[Laboratory examinations in forensic medical expertises on crimes against sexual integrity and sexual freedom]. [关于侵犯性完整和性自由罪的法医专家实验室检查]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/sudmed20246703110
A L Fedorovtsev, E I Koroleva, I S Edelev, N S Edelev

The article presents the results of analysis of 482 forensic biological and forensic cytological expertises on cases of sexual crimes. A presence of different types of such crimes has been noted. Expertises' effectiveness when examining content of vagina, oral cavity and rectum, impression smears and lavages from suspects' genital organs, subungual content of victims and suspects and other objects has been determined. The dependence of expertises' effectiveness on the terms of object removal has been noted. The article presents a number of objects' examination methods (luminescent-microscopic spermatozoids' identification, diagnosis of cells origin from mucous membranes of the vagina and oral cavity, determination of group belonging of specific cells in specimens, diagnosis of fecal masses presence) allowing to improve expertises' quality.

文章介绍了对 482 例性犯罪案件的法医生物学和法医细胞学鉴定的分析结果。文章指出了此类犯罪的不同类型。专家在检查阴道、口腔和直肠内容物、犯罪嫌疑人生殖器官的印模涂片和灌洗液、受害者和犯罪 嫌疑人的舌下内容物以及其他物体时的有效性已经确定。文章指出,专家的工作效率取决于移除物体的条件。文章介绍了多种物体检查方法(发光显微镜精子鉴定、阴道和口腔黏膜细胞来源诊断、标本中特定细胞群归属确定、粪便块存在诊断),有助于提高专家质量。
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引用次数: 0
[Morphology of sternum for formation of the biological profile of unidentified individual]. [胸骨形态学用于形成身份不明者的生物特征]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/sudmed20246703160
G V Zolotenkova, T A Tareeva

Identification of a person by general group characteristics does not lose its relevance over a long period. An analysis of publications (2000-2023) devoted to the possibilities of using the sternum to determine gender and age showed a fairly large amount of work on this topic, with very promising results. The trend in the development of this area is the use of modern methods of medical imaging. This becomes the starting point for conducting such studies on the territory of the Russian Federation and developing a methodology that includes the Russian population, taking into account their population characteristics.

通过一般群体特征来识别一个人在很长一段时间内都不会失去其相关性。对专门研究利用胸骨确定性别和年龄的可能性的出版物(2000-2023 年)进行的分析表明,在这一主题上开展了相当多的工作,并取得了非常可喜的成果。这一领域的发展趋势是使用现代医学成像方法。这成为在俄罗斯联邦领土上开展此类研究的起点,并根据俄罗斯人口的特点,制定出包括俄罗 斯人口在内的方法。
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引用次数: 0
[Mechanical asphyxia in the structure of violent death in the Russian Federation from 2013 to 2022 years]. [2013年至2022年俄罗斯联邦暴力死亡结构中的机械性窒息]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/sudmed20246702112
G V Zolotenkova, P V Minaeva, N V Polukhin, D P Kalashnikov

The objective of the study is to examine the death incidence from mechanical asphyxia in the Russian Federation in the period from 2013 to 2022 yr., to determine the dynamics of changes in indicators of its main types and to reveal territorial specificity. The results obtained with the use of medical statistics methods can be applied to implement measures for health protection, prevent risk factors of fatal outcome among population, to improve the training of forensic medical experts.

本研究的目的是调查 2013 年至 2022 年期间俄罗斯联邦机械性窒息死亡的发生率,确定其主要类型指标的动态变化,并揭示地区特殊性。利用医学统计方法得出的结果可用于实施健康保护措施、预防人口中致命结果的风险因素、改善法医专家的培训。
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引用次数: 0
[Features of lung damage in baclofen poisoning]. [巴氯芬中毒肺损伤的特征]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/sudmed20246701129
O L Romanova, M L Blagonravov, P G Djuvalyakov, E Kh Barinov, A V Ershov, M A Kislov

Objective: To reveal pathological lung changes in baclofen poisoning and to assess their dynamics.

Material and methods: The experiment included 20 mature (at age 20 weeks) male rats of Wistar line weighing 290-350 gr. The animals were divided into 3 study groups (5 rats in each) depending on experiment's duration after 85 mg/kg baclofen administration: 3, 4.5 and 24 h in the 1st, 2nd and 3rd groups, respectively. Control group consisted of 5 animals without baclofen administration.

Results: A number of pathological reactions, including circulatory disorder (venular and capillary congestion, hemorrhage in interalveolar septa, alveoli, sludge) and the appearance of emphysema loci (interalveolar septa at emphysema loci are thinned), alternating with atelectases and dystelectases. The area taken up by vessels after 4.5 h. baclofen administration was statistically significantly higher than in control group, and after 24 h. - statistically significantly higher than in 4.5 h. The area with white blood cells and WBC/IAP ratio after 4.5 h of baclofen administration were statistically significantly higher than in control group after 3 and 24 h of administration. The number of white blood cells, giving PAS positive reaction, increases during baclofen administration. The complex of pathological lung changes, revealed by ourselves, has a certain dynamics.

Conclusion: The data on morphological lung changes combined with results of chemical examination can be used to diagnose baclofen poisoning and to determine the time elapsed since this medicine administration.

目的:揭示巴氯芬中毒的肺部病理变化并评估其动态变化:揭示巴氯芬中毒的肺部病理变化并评估其动态变化:实验包括 20 只成熟(20 周龄)的 Wistar 系雄性大鼠,体重为 290-350 克。根据 85 毫克/千克巴氯芬给药后的实验持续时间,将动物分为 3 个研究组(每组 5 只):第一、第二和第三组分别为 3、4.5 和 24 小时。对照组由 5 只未服用巴氯芬的大鼠组成:出现了一系列病理反应,包括循环障碍(静脉和毛细血管充血、肺泡间隔出血、肺泡出血、淤血)和肺气肿病灶(肺气肿病灶处的肺泡间隔变薄),并交替出现脑电解质酶和脑电解质酶。据统计,服用巴氯芬 4.5 小时后,血管所占面积明显高于对照组;服用 24 小时后,血管所占面积明显高于服用 4.5 小时后。在服用巴氯芬期间,出现 PAS 阳性反应的白细胞数量增加。我们所发现的肺部病理变化的复合体具有一定的动态性:肺部形态学变化数据与化学检查结果相结合,可用于诊断巴氯芬中毒,并确定用药后的时间。
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引用次数: 0
[Personalized character of toxic effects through mass nonlethal poisoning by phenazepam and other psychoactive substances]. [通过苯西泮和其他精神活性物质造成的大规模非致命中毒,个性化地确定毒性效应的特征]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/sudmed20246701147
V D Akimova, S S Barsegyan, T V Pleteneva

Over several months, 14 people were admitted in 6 hospitals with severe symptoms of intoxication with psychoactive substances as a result of mass poisoning. All symptoms occurred after taking a drink that contained crushed phenazepam tablets. Samples of blood (n=10) and urine (n=6) taken from 14 sufferers for forensic, chemical and toxicological examination were analyzed using the HPLC-MS/MS method. Phenazepam was detected in the biomaterial of all 14 patients. Other psychoactive substances (baclofen, pregabalin, chlorprothixene, chlorpromazine, phenibut, tramadol, diazepam), narcotic substances and ethanol were also found in the sufferers. The phenazepam concentration in the blood was in the range of 109.75-786.50 ng/ml, in the urine - 8.97-101.28 ng/ml. The pharmacokinetic and toxicokinetic characteristics of toxicants as well as additional factors characterizing the phenotype of the sufferer in addition to drug's content in the biological material must be taken into account to determine the toxicity level of phenazepam against the background of combined action with other psychoactive substances.

几个月来,6 家医院收治了 14 名因集体中毒而出现精神活性物质中毒严重症状的患者。所有症状都是在服用了含有压碎的苯西泮药片的饮料后出现的。采用 HPLC-MS/MS 方法对 14 名中毒者的血液(10 人份)和尿液(6 人份)样本进行了法医、化学和毒理学检查分析。在所有 14 名患者的生物材料中都检测到了非那西泮。在患者体内还发现了其他精神活性物质(巴氯芬、普瑞巴林、氯普噻辛、氯丙嗪、菲尼布汀、曲马多、地西泮)、麻醉物质和乙醇。血液中的苯西泮浓度为 109.75-786.50 纳克/毫升,尿液中的苯西泮浓度为 8.97-101.28 纳克/毫升。在确定苯西泮与其他精神活性物质联合作用的毒性水平时,必须考虑到毒物的药代动力学和毒代动力学特征,以及除了生物物质中的药物含量外,患者表型特征的其他因素。
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引用次数: 0
[Qualitative and quantitative characteristics of structures of cerebral cortex structure in young people under conditions of chronic alcohol intoxication]. [慢性酒精中毒条件下青少年大脑皮层结构的定性和定量特征]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/sudmed20246701110
A O Saushkina, N S Averkin

Objective: To study morphological changes of cerebral cortex in young people under the conditions of chronic alcohol intoxication (CAI).

Material and methods: Morphometric examination of cerebral cortex fragments obtained from 28 persons who died with a CAI diagnosis (average age was 38 years), and 25 subjects who died from other causes, which are not associated with alcohol consumption (average age was 39 years), was carried out.

Results: It was shown that neurons of pathological shapes, including hypo- and hyperchromic, pyknotic and «shadow-like», were dominant in group of CAI. There was an increase in the glial index and a greater intensity of perivascular and pericellular edema compared to the control group.

Conclusion: Morphological changes of cerebral cortex under the conditions of CAI are non-specific and largely similar to neurodegenerative alterations in other pathological conditions, senile dementia. Clearer histological criteria for alcoholic encephalopathy are needed, including with the use of immunohistochemical methods.

目的:研究慢性酒精中毒(CAI)条件下青少年大脑皮层的形态学变化:研究慢性酒精中毒(CAI)条件下年轻人大脑皮层的形态变化:对28名被诊断为慢性酒精中毒死亡者(平均年龄38岁)和25名死于与饮酒无关的其他原因的受试者(平均年龄39岁)的大脑皮层片段进行形态学检查:结果表明,病理形态的神经元(包括低色素和高色素、脓结节和 "阴影样")在 CAI 组中占主导地位。与对照组相比,胶质细胞指数增加,血管周围和细胞周围水肿更严重:结论:在 CAI 条件下,大脑皮层的形态学变化是非特异性的,在很大程度上与其他病理条件下的神经退行性改变、老年痴呆症相似。酒精性脑病需要更明确的组织学标准,包括使用免疫组化方法。
{"title":"[Qualitative and quantitative characteristics of structures of cerebral cortex structure in young people under conditions of chronic alcohol intoxication].","authors":"A O Saushkina, N S Averkin","doi":"10.17116/sudmed20246701110","DOIUrl":"10.17116/sudmed20246701110","url":null,"abstract":"<p><strong>Objective: </strong>To study morphological changes of cerebral cortex in young people under the conditions of chronic alcohol intoxication (CAI).</p><p><strong>Material and methods: </strong>Morphometric examination of cerebral cortex fragments obtained from 28 persons who died with a CAI diagnosis (average age was 38 years), and 25 subjects who died from other causes, which are not associated with alcohol consumption (average age was 39 years), was carried out.</p><p><strong>Results: </strong>It was shown that neurons of pathological shapes, including hypo- and hyperchromic, pyknotic and «shadow-like», were dominant in group of CAI. There was an increase in the glial index and a greater intensity of perivascular and pericellular edema compared to the control group.</p><p><strong>Conclusion: </strong>Morphological changes of cerebral cortex under the conditions of CAI are non-specific and largely similar to neurodegenerative alterations in other pathological conditions, senile dementia. Clearer histological criteria for alcoholic encephalopathy are needed, including with the use of immunohistochemical methods.</p>","PeriodicalId":35704,"journal":{"name":"Sudebno-Meditsinskaya Ekspertisa","volume":"67 1","pages":"10-13"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139730671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Innovations in forensic medicine: accuracy, evidence and effectiveness of expertises in emergencies in case of mass fatality]. [法医学的创新:在发生大规模死亡事件的紧急情况下专家的准确性、证据和有效性]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/sudmed20246704122
Yu I Pigolkin, O I Kosukhina, E E Fomina, S V Leonov, V Yu Turbachkin, E N Leonova

The article presents the main innovative methods used in forensic expert practice at the current stage, reveals the principle and algorithms of the developed software complex for registration and identification of the deceased. The proposed program automatically generates four documents, which reduces the time required for forensic expertise in the conditions of mass admission of deceased. The article's authors substantiate prospects of further application of computer technologies in forensic practice to improve organizational and methodological activities in emergencies with a large number of deceased.

文章介绍了现阶段法医专家实践中使用的主要创新方法,揭示了所开发的死者登记和身份识别复合软件的原理和算法。所提议的程序可自动生成四份文件,从而减少了在大量接收死者的情况下法医专家所需的时间。文章作者证实了在法医实践中进一步应用计算机技术的前景,以改进在有大量死者的紧急情况下的组织和方法活动。
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引用次数: 0
[Is this iatrogenic pathology or rare disease?] [这是先天性病理还是罕见疾病?]
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/sudmed20246703145
O D Yagmurov, E P Fedotova, V A Fetisov, E Yu Kalinina, Z V Davydova, Yu V Shabanova

The article is devoted to the problem of diagnosis and treatment strategy of Buerger's disease rarely found in the expert and clinical practice, that is inflammatory disease of unknown etiology, affecting mainly small and medium arteries and veins of limbs. Vascular surgeons around the world have been solving this problem for many years, both in terms of timely diagnosis of this disease and its proper pathogenic treatment. The authors of the article described an expert case of Buerger's disease larvated course in 15-years-old girl, which primarily was mistakenly assessed by specialists as iatrogenic pathology of right forearm vessels in injecting aminazin solution that, according to the clinicians' opinion, led to dry gangrene formation of right wrist and its subsequent amputation. The results of the forensic histological study and retrospective analysis of all child's medical documents allowed to correctly diagnose this rare pathology but only on the stage of commission forensic medical examination in the framework of the initiated criminal proceeding against several leading medical organizations in Saint-Petersburg with a pediatric profile. The authors noted the role of routine medical manipulation in manifestation of larvated pathologic process in a teenage girl in addition to full health and well-being. The objective of present article is devoted to understanding this problem.

布格氏病是一种病因不明的炎症性疾病,主要累及四肢的中小动脉和静脉。多年来,世界各地的血管外科医生一直在解决这个问题,既要及时诊断这种疾病,又要进行正确的病因治疗。文章作者描述了一个 15 岁女孩布格氏病幼虫病程的专家病例,该病例主要被专家误认为是右前臂血管在注射氨基嗪溶液时发生的先天性病变,根据临床医生的意见,该病例导致右腕干性坏疽形成,随后被截肢。法医组织学研究的结果和对所有儿童医疗文件的回顾性分析使我们能够正确诊断出这种罕见的病症,但这只是在对圣彼得堡几家具有儿科背景的主要医疗机构提起刑事诉讼的框架内进行委托法医检查的阶段。作者指出,除了完全健康和良好的身体状况外,常规医疗操作在少女幼虫病变过程中也发挥了作 用。本文的目的就在于了解这一问题。
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引用次数: 0
[Possibilities of using results of head computed tomography in victims with traumatic brain injuries]. [在脑外伤患者中使用头部计算机断层扫描结果的可能性]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/sudmed20246703124
E V Egorova, E M Kildyushov, D V Burenchev

The constant increase in the number of neurotraumas in the country leads to an increase in forensic examinations of a persons. In Russia, about 600 thousand people receive craniocerebral injuries annually, of which 50 thousand die, others are potentially will be in forensic examination during or after treatment. With an increase in the total number of such examinations, the number of erroneous conclusions is expected to increase. If it is impossible for the radiologist included in the commission to review the results of computed tomography of the head performed in the hospital, the experts are forced to use the data that are recorded in the medical documents. The present study revealed the percentage of erroneous interpretations in such descriptions, systematized typical errors, calculated the sensitivity, specificity and accuracy of computed tomography in craniocerebral injury.

国内神经创伤数量的持续增长导致了法医检查人数的增加。在俄罗斯,每年约有 60 万人受到颅脑损伤,其中 5 万人死亡,其他人可能在治疗期间或治疗后接受法医检查。随着此类检查总数的增加,预计错误结论的数量也会增加。如果委员会中的放射科医生无法审查在医院进行的头部计算机断层扫描结果,专家们就不得不使用医疗文件中记录的数据。本研究揭示了此类描述中错误解释的百分比,将典型错误系统化,计算了颅脑损伤计算机断层扫描的敏感性、特异性和准确性。
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引用次数: 0
期刊
Sudebno-Meditsinskaya Ekspertisa
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