首页 > 最新文献

International Journal of Clinical Pediatric Dentistry最新文献

英文 中文
Efficacy and Pain Perception of a Comfort-in™ for Palatal Anesthesia in Pediatric Dental Patients: A Randomized Controlled Trial. Comfort-in™用于儿科牙科患者腭麻醉的疗效和痛觉:一项随机对照试验。
Q3 Dentistry Pub Date : 2026-02-01 Epub Date: 2026-02-12 DOI: 10.5005/jp-journals-10005-3418
Shilpa S Naik, Sanjana R Kodical, Amil Joshi, Sonal Mali, Rhea Shah, Nidhi Shetiya

Background: Needle phobia is frequently observed in children, contributing to heightened dental anxiety, uncooperative behavior, and care avoidance. The sight or sensation of traditional anesthesia needles can provoke intense emotional responses, complicating pediatric pain management. This study assesses the Comfort-in™ needle-free jet injector as an alternative, aiming to enhance anesthetic delivery, patient comfort, and cooperation during pediatric dental procedures.

Aim: To assess the effectiveness of the Comfort-in™ system in minimizing pain during local anesthesia (LA) administration in pediatric dental procedures.

Materials and methods: This randomized controlled trial included 64 children aged 4-9 years undergoing tooth extractions involving buccal and palatal infiltrations. Participants were randomly assigned to receive anesthesia via either a conventional needle syringe (group I) or the Comfort-in™ jet injector (group II). Pulse rate, behavior, pain, and local anesthetic effectiveness were evaluated.

Results: The difference in pulse rates during LA administration and during treatment was statistically significant between the two groups (p = 0.000 and 0.000, respectively); with a lower pulse rate seen with the jet injector group, suggesting that the child had lower anxiety with the jet injector group. Similar results were seen with other parameters such as time required, LA efficacy, Wong-Baker FACES pain rating scale, and modified behavior rating scale by Taddio et al.

Conclusion: Considering the limitations of the present study, the Comfort-in™ system demonstrated effectiveness as a needle-free alternative for minimizing pain and anxiety in pediatric patients, while also significantly reducing the time required for LA administration.

How to cite this article: Naik SS, Kodical SR, Joshi A, et al. Efficacy and Pain Perception of a Comfort-in™ for Palatal Anesthesia in Pediatric Dental Patients: A Randomized Controlled Trial. Int J Clin Pediatr Dent 2026;19(2):228-233.

背景:针恐惧症在儿童中经常观察到,导致牙科焦虑加剧,不合作行为和护理逃避。传统麻醉针的视觉或感觉会引起强烈的情绪反应,使儿科疼痛管理复杂化。本研究评估了comfort -in™无针喷射注射器作为一种替代方案,旨在提高儿科牙科手术中的麻醉输送、患者舒适度和合作。目的:评估Comfort-in™系统在儿童牙科手术中减少局部麻醉(LA)给药时疼痛的有效性。材料和方法:这项随机对照试验包括64名4-9岁的儿童,他们接受了包括口腔和腭浸润的拔牙手术。参与者被随机分配通过传统针头注射器(I组)或Comfort-in™喷射注射器(II组)接受麻醉。评估脉搏率、行为、疼痛和局部麻醉效果。结果:两组在给药期间和治疗期间脉搏率差异有统计学意义(p分别= 0.000和0.000);注射组的脉搏率较低,这表明注射组的孩子焦虑程度较低。其他参数,如所需时间、LA疗效、Wong-Baker FACES疼痛评定量表和Taddio等人的改良行为评定量表,也得到了类似的结果。结论:考虑到本研究的局限性,Comfort-in™系统证明了作为一种无针替代方案的有效性,可以最大限度地减少儿科患者的疼痛和焦虑,同时也显著减少了LA给药所需的时间。如何引用:Naik SS, Kodical SR, Joshi A等。Comfort-in™用于儿科牙科患者腭麻醉的疗效和痛觉:一项随机对照试验。中华临床儿科杂志,2016;19(2):228-233。
{"title":"Efficacy and Pain Perception of a Comfort-in™ for Palatal Anesthesia in Pediatric Dental Patients: A Randomized Controlled Trial.","authors":"Shilpa S Naik, Sanjana R Kodical, Amil Joshi, Sonal Mali, Rhea Shah, Nidhi Shetiya","doi":"10.5005/jp-journals-10005-3418","DOIUrl":"10.5005/jp-journals-10005-3418","url":null,"abstract":"<p><strong>Background: </strong>Needle phobia is frequently observed in children, contributing to heightened dental anxiety, uncooperative behavior, and care avoidance. The sight or sensation of traditional anesthesia needles can provoke intense emotional responses, complicating pediatric pain management. This study assesses the Comfort-in™ needle-free jet injector as an alternative, aiming to enhance anesthetic delivery, patient comfort, and cooperation during pediatric dental procedures.</p><p><strong>Aim: </strong>To assess the effectiveness of the Comfort-in™ system in minimizing pain during local anesthesia (LA) administration in pediatric dental procedures.</p><p><strong>Materials and methods: </strong>This randomized controlled trial included 64 children aged 4-9 years undergoing tooth extractions involving buccal and palatal infiltrations. Participants were randomly assigned to receive anesthesia <i>via</i> either a conventional needle syringe (group I) or the Comfort-in™ jet injector (group II). Pulse rate, behavior, pain, and local anesthetic effectiveness were evaluated.</p><p><strong>Results: </strong>The difference in pulse rates during LA administration and during treatment was statistically significant between the two groups (<i>p</i> = 0.000 and 0.000, respectively); with a lower pulse rate seen with the jet injector group, suggesting that the child had lower anxiety with the jet injector group. Similar results were seen with other parameters such as time required, LA efficacy, Wong-Baker FACES pain rating scale, and modified behavior rating scale by Taddio et al.</p><p><strong>Conclusion: </strong>Considering the limitations of the present study, the Comfort-in™ system demonstrated effectiveness as a needle-free alternative for minimizing pain and anxiety in pediatric patients, while also significantly reducing the time required for LA administration.</p><p><strong>How to cite this article: </strong>Naik SS, Kodical SR, Joshi A, <i>et al.</i> Efficacy and Pain Perception of a Comfort-in™ for Palatal Anesthesia in Pediatric Dental Patients: A Randomized Controlled Trial. Int J Clin Pediatr Dent 2026;19(2):228-233.</p>","PeriodicalId":36045,"journal":{"name":"International Journal of Clinical Pediatric Dentistry","volume":"19 2","pages":"228-233"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147379016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Phenylthiocarbamide Taste Sensitivity with Dental Caries, Skeletal Maturity, and Body Mass Index Percentiles in Children Aged 8-12 Years: A Cross-sectional Study. 8-12岁儿童苯硫胺味觉敏感性与龋齿、骨骼成熟度和体重指数百分位数的关联:一项横断面研究。
Q3 Dentistry Pub Date : 2026-02-01 Epub Date: 2026-02-12 DOI: 10.5005/jp-journals-10005-3449
Anusha Dixit, Ashish Saxena, Neha Verma, Vishal Khandelwal

Background: Taste perception, shaped by both genetic makeup and environmental influences, plays an important role in dietary habits and overall health. Sensitivity to phenylthiocarbamide (PTC), which is controlled by variations in the TAS2R38 gene, categorizes individuals as either tasters or nontasters. This distinction can affect food preferences and may contribute to differences in susceptibility to dental caries. Research has shown associations between PTC-tasting ability and dental caries, skeletal development, and body mass index (BMI), highlighting its potential usefulness in evaluating caries risk and informing growth-related assessments.

Objective: To evaluate the association of PTC taste sensitivity with dental caries experience, skeletal maturation, and BMI percentiles among individuals classified as tasters and nontasters.

Materials and methods: A total of 96 children between the ages of 8 and 12 were randomly chosen for the study. PTC taste sensitivity was determined using a standardized taste test. Skeletal development was assessed via radiovisiography (RVG) of the middle phalanx. BMI was calculated using standard anthropometric measurements and classified into percentiles based on the IAP Pediatric Growth Charts. Dental caries experience was recorded using decayed, extracted, and filled teeth (deft) and decayed, missing, and filled teeth (DMFT) indices.

Results: Nontasters had significantly more carious teeth than tasters (p-value < 0.001). However, no significant differences in BMI or skeletal maturity were observed between tasters and nontasters (p-value = 0.738) and (p-value = 0.555), respectively.

Conclusion: PTC taste sensitivity may help assess dental caries risk in children. While no significant links were found between PTC sensitivity, obesity, or skeletal maturity, the findings emphasize the importance of taste perception in dietary choices and oral health. Further research is needed to understand the mechanisms linking taste sensitivity to health outcomes.

Clinical significance: PTC testing could help clinicians identify cavity-prone children and tailor preventive strategies, with future research exploring taste-based interventions to improve diet and oral health.

How to cite this article: Dixit A, Saxena A, Verma N, et al. Association of Phenylthiocarbamide Taste Sensitivity with Dental Caries, Skeletal Maturity, and Body Mass Index Percentiles in Children Aged 8-12 Years: A Cross-sectional Study. Int J Clin Pediatr Dent 2026;19(2):190-194.

背景:味觉受基因组成和环境影响的影响,在饮食习惯和整体健康中起着重要作用。对苯硫胺(PTC)的敏感性是由TAS2R38基因的变异控制的,它将个体分为味觉者和味觉者。这种区别会影响食物偏好,并可能导致龋齿易感性的差异。研究表明ptc品尝能力与龋齿、骨骼发育和体重指数(BMI)之间存在关联,强调了其在评估龋齿风险和为生长相关评估提供信息方面的潜在用途。目的:评估味觉者和非味觉者之间PTC味觉敏感性与龋齿经历、骨骼成熟度和BMI百分位数的关系。材料与方法:随机选取96名年龄在8 ~ 12岁的儿童进行研究。PTC味觉敏感度采用标准化味觉测试确定。通过中指骨放射显像(RVG)评估骨骼发育。BMI使用标准人体测量值计算,并根据IAP儿科生长图表分类为百分位数。使用蛀牙、拔牙和补牙(deft)和蛀牙、缺牙和补牙(DMFT)指数记录龋病经历。结果:不品尝者的龋病发生率明显高于品尝者(p值< 0.001)。然而,品酒者和非品酒者在BMI和骨骼成熟度方面分别没有显著差异(p值= 0.738)和(p值= 0.555)。结论:PTC味觉敏感性有助于评估儿童龋病风险。虽然没有发现PTC敏感性、肥胖或骨骼成熟度之间的显著联系,但研究结果强调了味觉在饮食选择和口腔健康中的重要性。需要进一步的研究来了解味觉敏感性与健康结果之间的联系机制。临床意义:PTC测试可以帮助临床医生识别易患蛀牙的儿童,并制定预防策略,未来的研究将探索基于口味的干预措施,以改善饮食和口腔健康。本文引用方式:Dixit A, Saxena A, Verma N等。8-12岁儿童苯硫胺味觉敏感性与龋齿、骨骼成熟度和体重指数百分位数的关联:一项横断面研究。中华临床儿科杂志,2016;19(2):190-194。
{"title":"Association of Phenylthiocarbamide Taste Sensitivity with Dental Caries, Skeletal Maturity, and Body Mass Index Percentiles in Children Aged 8-12 Years: A Cross-sectional Study.","authors":"Anusha Dixit, Ashish Saxena, Neha Verma, Vishal Khandelwal","doi":"10.5005/jp-journals-10005-3449","DOIUrl":"10.5005/jp-journals-10005-3449","url":null,"abstract":"<p><strong>Background: </strong>Taste perception, shaped by both genetic makeup and environmental influences, plays an important role in dietary habits and overall health. Sensitivity to phenylthiocarbamide (PTC), which is controlled by variations in the <i>TAS2R38</i> gene, categorizes individuals as either tasters or nontasters. This distinction can affect food preferences and may contribute to differences in susceptibility to dental caries. Research has shown associations between PTC-tasting ability and dental caries, skeletal development, and body mass index (BMI), highlighting its potential usefulness in evaluating caries risk and informing growth-related assessments.</p><p><strong>Objective: </strong>To evaluate the association of PTC taste sensitivity with dental caries experience, skeletal maturation, and BMI percentiles among individuals classified as tasters and nontasters.</p><p><strong>Materials and methods: </strong>A total of 96 children between the ages of 8 and 12 were randomly chosen for the study. PTC taste sensitivity was determined using a standardized taste test. Skeletal development was assessed <i>via</i> radiovisiography (RVG) of the middle phalanx. BMI was calculated using standard anthropometric measurements and classified into percentiles based on the IAP Pediatric Growth Charts. Dental caries experience was recorded using decayed, extracted, and filled teeth (deft) and decayed, missing, and filled teeth (DMFT) indices.</p><p><strong>Results: </strong>Nontasters had significantly more carious teeth than tasters (<i>p</i>-value < 0.001). However, no significant differences in BMI or skeletal maturity were observed between tasters and nontasters (<i>p</i>-value = 0.738) and (<i>p</i>-value = 0.555), respectively.</p><p><strong>Conclusion: </strong>PTC taste sensitivity may help assess dental caries risk in children. While no significant links were found between PTC sensitivity, obesity, or skeletal maturity, the findings emphasize the importance of taste perception in dietary choices and oral health. Further research is needed to understand the mechanisms linking taste sensitivity to health outcomes.</p><p><strong>Clinical significance: </strong>PTC testing could help clinicians identify cavity-prone children and tailor preventive strategies, with future research exploring taste-based interventions to improve diet and oral health.</p><p><strong>How to cite this article: </strong>Dixit A, Saxena A, Verma N, <i>et al.</i> Association of Phenylthiocarbamide Taste Sensitivity with Dental Caries, Skeletal Maturity, and Body Mass Index Percentiles in Children Aged 8-12 Years: A Cross-sectional Study. Int J Clin Pediatr Dent 2026;19(2):190-194.</p>","PeriodicalId":36045,"journal":{"name":"International Journal of Clinical Pediatric Dentistry","volume":"19 2","pages":"190-194"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Evaluation of Clinical and Radiographic Success Rates of Direct Pulp Capping in Primary Molars Using TheraCal LC, 3Mixtatin, and Nanohydroxyapatite: An In Vivo Study. 使用LC、3mixatin和纳米羟基磷灰石直接盖牙的临床和影像学成功率比较:一项体内研究。
Q3 Dentistry Pub Date : 2026-02-01 Epub Date: 2026-02-12 DOI: 10.5005/jp-journals-10005-3416
Bala Prasanthi Borusu, Punithavathy Naren, Satyam Martha, Sri Ramya Maganti, K Haritha, Harshitha Yaramala

Aim and background: This in vivo study evaluated and compared the clinical and radiographic efficacy of three pulp capping agents-TheraCal light-cured (LC), 3Mixtatin, and nanohydroxyapatite (NHA)-for direct pulp capping (DPC) in primary molars. The goal aligns with the modern focus of pediatric dentistry on pulp revitalization and the preservation of primary teeth until exfoliation.

Methods: Forty-five primary molars from children aged 3-9 years, exhibiting pinpoint pulp exposures (≤1 mm) with hemostasis achieved within 2-3 minutes, were randomly assigned (n = 15 per group) to receive TheraCal LC, 3Mixtatin, or NHA. All treatments were sealed with zinc oxide eugenol and restored with type IX glass ionomer cement. Clinical and radiographic assessments-evaluating pain, swelling, sinus tract, percussion sensitivity, mobility, secondary caries, root resorption, furcal radiolucency, and periodontal ligament (PDL) widening-were conducted at 3, 6, and 9 months. The collected data were analyzed using the Chi-square test with the aid of Statistical Package for the Social Sciences (SPSS) software.

Results: TheraCal LC showed 100% success at 3 and 6 months, slightly declining at 9 months (86.7% clinical, 93.3% radiographic). 3Mixtatin showed a steep drop to 53.3% clinical and 60% radiographic success at 9 months, with notable sinus tract formation and furcal radiolucency (p < 0.01). NHA maintained 100% success at 6 months and 93.3% at 9 months both clinically and radiographically.

Conclusion: Nanohydroxyapatite exhibited the highest and most consistent success over the 9 months, outperforming both TheraCal LC and 3Mixtatin in sustaining pulp vitality.

Clinical significance: The success of DPC in primary teeth is largely influenced by the use of materials with optimal biological compatibility. NHA demonstrated superior outcomes, offering effective pulp preservation and reducing the need for invasive treatments.

How to cite this article: Borusu BP, Naren P, Martha S, et al. Comparative Evaluation of Clinical and Radiographic Success Rates of Direct Pulp Capping in Primary Molars Using TheraCal LC, 3Mixtatin, and Nanohydroxyapatite: An In Vivo Study. Int J Clin Pediatr Dent 2026;19(2):215-222.

目的和背景:本体内研究评估并比较了三种牙髓盖盖剂——theracal光固化(LC)、3Mixtatin和纳米羟基磷灰石(NHA)——用于直接盖髓(DPC)的临床和放射学效果。目标与现代儿科牙科对牙髓振兴和保存原牙直到去角质的焦点一致。方法:45例3-9岁儿童的初生磨牙,表现为尖牙髓暴露(≤1mm),在2-3分钟内止血,随机分配(每组n = 15)接受TheraCal LC, 3Mixtatin或NHA。所有处理均用氧化锌丁香酚密封,并用IX型玻璃离子水门汀修复。在3、6和9个月时进行临床和影像学评估,包括疼痛、肿胀、窦道、冲击敏感性、活动能力、继发龋病、牙根吸收、牙根透光度和牙周韧带(PDL)加宽。使用SPSS软件对收集到的数据进行卡方检验。结果:TheraCal LC在3个月和6个月时成功率为100%,在9个月时略有下降(临床86.7%,影像学93.3%)。mixtatin在9个月时临床成功率急剧下降至53.3%,影像学成功率为60%,窦道形成和分叉透光度显著(p < 0.01)。NHA在6个月时保持100%的成功率,在9个月时保持93.3%的成功率。结论:纳米羟基磷灰石在9个月内表现出最高和最一致的成功,在维持牙髓活力方面优于TheraCal LC和3mixatin。临床意义:乳牙DPC的成功与否很大程度上取决于材料的生物相容性。NHA表现出优越的结果,提供有效的牙髓保存和减少侵入性治疗的需要。如何引用本文:Borusu BP, Naren P, Martha S等。使用LC、3mixatin和纳米羟基磷灰石直接盖牙的临床和影像学成功率比较:一项体内研究。中华临床儿科杂志,2016;19(2):215-222。
{"title":"Comparative Evaluation of Clinical and Radiographic Success Rates of Direct Pulp Capping in Primary Molars Using TheraCal LC, 3Mixtatin, and Nanohydroxyapatite: An <i>In Vivo</i> Study.","authors":"Bala Prasanthi Borusu, Punithavathy Naren, Satyam Martha, Sri Ramya Maganti, K Haritha, Harshitha Yaramala","doi":"10.5005/jp-journals-10005-3416","DOIUrl":"10.5005/jp-journals-10005-3416","url":null,"abstract":"<p><strong>Aim and background: </strong>This <i>in vivo</i> study evaluated and compared the clinical and radiographic efficacy of three pulp capping agents-TheraCal light-cured (LC), 3Mixtatin, and nanohydroxyapatite (NHA)-for direct pulp capping (DPC) in primary molars. The goal aligns with the modern focus of pediatric dentistry on pulp revitalization and the preservation of primary teeth until exfoliation.</p><p><strong>Methods: </strong>Forty-five primary molars from children aged 3-9 years, exhibiting pinpoint pulp exposures (≤1 mm) with hemostasis achieved within 2-3 minutes, were randomly assigned (<i>n</i> = 15 per group) to receive TheraCal LC, 3Mixtatin, or NHA. All treatments were sealed with zinc oxide eugenol and restored with type IX glass ionomer cement. Clinical and radiographic assessments-evaluating pain, swelling, sinus tract, percussion sensitivity, mobility, secondary caries, root resorption, furcal radiolucency, and periodontal ligament (PDL) widening-were conducted at 3, 6, and 9 months. The collected data were analyzed using the Chi-square test with the aid of Statistical Package for the Social Sciences (SPSS) software.</p><p><strong>Results: </strong>TheraCal LC showed 100% success at 3 and 6 months, slightly declining at 9 months (86.7% clinical, 93.3% radiographic). 3Mixtatin showed a steep drop to 53.3% clinical and 60% radiographic success at 9 months, with notable sinus tract formation and furcal radiolucency (<i>p</i> < 0.01). NHA maintained 100% success at 6 months and 93.3% at 9 months both clinically and radiographically.</p><p><strong>Conclusion: </strong>Nanohydroxyapatite exhibited the highest and most consistent success over the 9 months, outperforming both TheraCal LC and 3Mixtatin in sustaining pulp vitality.</p><p><strong>Clinical significance: </strong>The success of DPC in primary teeth is largely influenced by the use of materials with optimal biological compatibility. NHA demonstrated superior outcomes, offering effective pulp preservation and reducing the need for invasive treatments.</p><p><strong>How to cite this article: </strong>Borusu BP, Naren P, Martha S, <i>et al.</i> Comparative Evaluation of Clinical and Radiographic Success Rates of Direct Pulp Capping in Primary Molars Using TheraCal LC, 3Mixtatin, and Nanohydroxyapatite: An <i>In Vivo</i> Study. Int J Clin Pediatr Dent 2026;19(2):215-222.</p>","PeriodicalId":36045,"journal":{"name":"International Journal of Clinical Pediatric Dentistry","volume":"19 2","pages":"215-222"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Clinical Performance of Preformed CAD/CAM Milled PMMA Crown and Stainless Steel Crown for Primary Molar Teeth Using Dental Operating Microscope. 牙科手术显微镜下预制CAD/CAM磨PMMA冠与不锈钢冠的临床性能比较
Q3 Dentistry Pub Date : 2026-02-01 Epub Date: 2026-02-12 DOI: 10.5005/jp-journals-10005-3400
A K Shanmugaavel, Priyanka Balakrishnan, Taslima Nandhini, Ranjith Akshay Seshari Iyer, Daya Srinivasan, Ar Senthil Eagappan

Background: Full-coverage restorations are essential for the long-term preservation of extensively carious primary molars. While preformed stainless steel crowns (P-SSCs) are the gold standard due to their durability, esthetic concerns have led to the development of alternative options such as preformed 3D-milled polymethylmethacrylate (P-PMMA) crowns, which offer improved appearance and marginal adaptation.

Aim: To compare the clinical efficiency of P-PMMA crowns and P-SSCs in restoring mandibular second primary molars over a 6-month period in terms of gingival health, occlusal wear, and crown failure/dislodgement.

Materials and methods: A randomized controlled clinical trial was conducted on 34 children aged 4-8 years with bilateral carious mandibular second primary molars. Using a split-mouth design, one molar received a P-SSC and the contralateral molar received a P-PMMA crown. Clinical evaluations were performed at baseline, 3 months, and 6 months. Parameters assessed included gingival health (using modified gingival index), occlusal wear (visual-tactile assessment), and crown retention. Data were analyzed using paired t-tests and Chi-square tests (p < 0.05 considered significant).

Results: Both crown types demonstrated satisfactory performance at 6 months. P-SSCs showed slightly higher retention rates, while P-PMMA crowns had better esthetic outcomes and comparable gingival health. No statistically significant differences were observed in occlusal wear between the groups.

Conclusion: Preformed polymethylmethacrylate crowns are a clinically acceptable esthetic alternative to P-SSCs for mandibular second primary molars, showing comparable short-term performance with enhanced patient and parent satisfaction.

How to cite this article: Shanmugaavel AK, Balakrishnan P, Nandhini T, et al. Comparison of Clinical Performance of Preformed CAD/CAM Milled PMMA Crown and Stainless Steel Crown for Primary Molar Teeth Using Dental Operating Microscope. Int J Clin Pediatr Dent 2026;19(2):139-144.

背景:全覆盖修复体对于长期保存大面积龋病的初级磨牙是必不可少的。虽然预成型不锈钢冠(p - ssc)因其耐用性而成为黄金标准,但美学方面的考虑导致了替代方案的发展,例如预成型3d铣聚甲基丙烯酸甲酯(P-PMMA)冠,它提供了更好的外观和边缘适应性。目的:比较P-PMMA牙冠与p - ssc牙冠修复下颌第二磨牙6个月后牙龈健康、咬合磨损、牙冠失效/移位的临床疗效。材料与方法:对34例4 ~ 8岁双侧下颌第二磨牙龋齿患儿进行随机对照临床试验。采用裂口设计,一侧磨牙安装P-SSC,对侧磨牙安装P-PMMA冠。在基线、3个月和6个月时进行临床评估。评估的参数包括牙龈健康(使用改良的牙龈指数)、咬合磨损(视觉-触觉评估)和冠固位。数据分析采用配对t检验和卡方检验(p < 0.05认为显著)。结果:两种冠型在6个月时均表现满意。p - ssc的保留率略高,而P-PMMA冠具有更好的美观效果和可比较的牙龈健康。两组间牙合磨损无统计学差异。结论:预制聚甲基丙烯酸甲酯冠是临床可接受的下颌第二磨牙P-SSCs的美学替代品,其短期性能可提高患者和家长的满意度。如何引用本文:Shanmugaavel AK, Balakrishnan P, Nandhini T等。牙科手术显微镜下预制CAD/CAM磨PMMA冠与不锈钢冠的临床性能比较中华临床儿科杂志,2016;19(2):139-144。
{"title":"Comparison of Clinical Performance of Preformed CAD/CAM Milled PMMA Crown and Stainless Steel Crown for Primary Molar Teeth Using Dental Operating Microscope.","authors":"A K Shanmugaavel, Priyanka Balakrishnan, Taslima Nandhini, Ranjith Akshay Seshari Iyer, Daya Srinivasan, Ar Senthil Eagappan","doi":"10.5005/jp-journals-10005-3400","DOIUrl":"10.5005/jp-journals-10005-3400","url":null,"abstract":"<p><strong>Background: </strong>Full-coverage restorations are essential for the long-term preservation of extensively carious primary molars. While preformed stainless steel crowns (P-SSCs) are the gold standard due to their durability, esthetic concerns have led to the development of alternative options such as preformed 3D-milled polymethylmethacrylate (P-PMMA) crowns, which offer improved appearance and marginal adaptation.</p><p><strong>Aim: </strong>To compare the clinical efficiency of P-PMMA crowns and P-SSCs in restoring mandibular second primary molars over a 6-month period in terms of gingival health, occlusal wear, and crown failure/dislodgement.</p><p><strong>Materials and methods: </strong>A randomized controlled clinical trial was conducted on 34 children aged 4-8 years with bilateral carious mandibular second primary molars. Using a split-mouth design, one molar received a P-SSC and the contralateral molar received a P-PMMA crown. Clinical evaluations were performed at baseline, 3 months, and 6 months. Parameters assessed included gingival health (using modified gingival index), occlusal wear (visual-tactile assessment), and crown retention. Data were analyzed using paired <i>t</i>-tests and Chi-square tests (<i>p</i> < 0.05 considered significant).</p><p><strong>Results: </strong>Both crown types demonstrated satisfactory performance at 6 months. P-SSCs showed slightly higher retention rates, while P-PMMA crowns had better esthetic outcomes and comparable gingival health. No statistically significant differences were observed in occlusal wear between the groups.</p><p><strong>Conclusion: </strong>Preformed polymethylmethacrylate crowns are a clinically acceptable esthetic alternative to P-SSCs for mandibular second primary molars, showing comparable short-term performance with enhanced patient and parent satisfaction.</p><p><strong>How to cite this article: </strong>Shanmugaavel AK, Balakrishnan P, Nandhini T, <i>et al.</i> Comparison of Clinical Performance of Preformed CAD/CAM Milled PMMA Crown and Stainless Steel Crown for Primary Molar Teeth Using Dental Operating Microscope. Int J Clin Pediatr Dent 2026;19(2):139-144.</p>","PeriodicalId":36045,"journal":{"name":"International Journal of Clinical Pediatric Dentistry","volume":"19 2","pages":"139-144"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Evaluation of the Effect of Different Concentrations of Silver Diamine Fluoride on the Shear Bond Strength of Composite Resin on Primary Tooth Dentin: An In Vitro Study. 不同浓度氟化二胺银对复合树脂对乳牙本质剪切结合强度影响的体外比较研究
Q3 Dentistry Pub Date : 2026-02-01 Epub Date: 2026-02-12 DOI: 10.5005/jp-journals-10005-3417
Sanjana Deka, Seema Chaudhary, Naveen Manuja, Chaitra Ravishankar Telgi, Ashish Amit Sinha, Kounali Parasar

Background: Silver diamine fluoride (SDF) is a nominally invasive agent for caries arrest, but its impact on composite resin bond strength in primary teeth remains unclear.

Aim: To review the effect of different SDF concentrations (12%, 30%, 38%) on the shear bond strength (SBS) of resin composite to primary tooth dentin.

Materials and methods: Forty surgically removed primary teeth were assigned to four groups: Control (no SDF) and three experimental groups (12%, 30%, or 38% SDF). After demineralization and SDF application, the resin composite was bonded to dentin. SBS was quantified with the aid of a universal testing machine, and the data were subjected to statistical evaluation.

Results: The control group showed the highest SBS (10.28 MPa), while SDF-treated groups exhibited significantly lower values (7.36-7.72 MPa). The analysis revealed no statistically significant intergroup disparity among the SDF concentrations (p > 0.05).

Conclusion: SDF pretreatment reduces composite resin bond strength to primary dentin, but the concentration (12-38%) does not significantly influence the outcome. Clinicians should consider this when combining SDF with composite restorations.

Clinical significance: Despite a reduction in bond strength, this study supports the use of SDF because of its therapeutic efficacy in arresting carious lesions in primary teeth, as different concentrations (12-38%) do not significantly affect composite bonding. SDF can be confidently used in minimally invasive pediatric care where long-term caries control is a priority.

How to cite this article: Deka S, Chaudhary S, Manuja N, et al. Comparative Evaluation of the Effect of Different Concentrations of Silver Diamine Fluoride on the Shear Bond Strength of Composite Resin on Primary Tooth Dentin: An In Vitro Study. Int J Clin Pediatr Dent 2026;19(2):223-227.

背景:氟化二胺银(SDF)名义上是一种有创阻龋剂,但其对乳牙复合树脂结合强度的影响尚不清楚。目的:探讨不同SDF浓度(12%、30%、38%)对树脂复合材料与原牙本质剪切结合强度(SBS)的影响。材料和方法:将40颗手术拔除的乳牙分为4组:对照组(无SDF)和3个实验组(SDF为12%、30%或38%)。在脱矿和SDF应用后,树脂复合材料与牙本质结合。利用万能试验机对SBS进行量化,并对数据进行统计评价。结果:对照组SBS最高(10.28 MPa), sdf处理组显著低于对照组(7.36 ~ 7.72 MPa)。SDF浓度组间差异无统计学意义(p < 0.05)。结论:SDF预处理降低了复合树脂与初级牙本质的结合强度,但浓度(12-38%)对结果影响不显著。临床医生在结合SDF和复合修复体时应考虑到这一点。临床意义:尽管结合强度降低,但本研究支持使用SDF,因为它具有抑制乳牙龋齿病变的治疗效果,不同浓度(12-38%)对复合结合没有显著影响。SDF可以自信地用于微创儿科护理,长期控制龋齿是一个优先事项。如何引用本文:Deka S, Chaudhary S, Manuja N等。不同浓度氟化二胺银对复合树脂对乳牙本质剪切结合强度影响的体外比较研究中华临床儿科杂志,2016;19(2):223-227。
{"title":"Comparative Evaluation of the Effect of Different Concentrations of Silver Diamine Fluoride on the Shear Bond Strength of Composite Resin on Primary Tooth Dentin: An <i>In Vitro</i> Study.","authors":"Sanjana Deka, Seema Chaudhary, Naveen Manuja, Chaitra Ravishankar Telgi, Ashish Amit Sinha, Kounali Parasar","doi":"10.5005/jp-journals-10005-3417","DOIUrl":"10.5005/jp-journals-10005-3417","url":null,"abstract":"<p><strong>Background: </strong>Silver diamine fluoride (SDF) is a nominally invasive agent for caries arrest, but its impact on composite resin bond strength in primary teeth remains unclear.</p><p><strong>Aim: </strong>To review the effect of different SDF concentrations (12%, 30%, 38%) on the shear bond strength (SBS) of resin composite to primary tooth dentin.</p><p><strong>Materials and methods: </strong>Forty surgically removed primary teeth were assigned to four groups: Control (no SDF) and three experimental groups (12%, 30%, or 38% SDF). After demineralization and SDF application, the resin composite was bonded to dentin. SBS was quantified with the aid of a universal testing machine, and the data were subjected to statistical evaluation.</p><p><strong>Results: </strong>The control group showed the highest SBS (10.28 MPa), while SDF-treated groups exhibited significantly lower values (7.36-7.72 MPa). The analysis revealed no statistically significant intergroup disparity among the SDF concentrations (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>SDF pretreatment reduces composite resin bond strength to primary dentin, but the concentration (12-38%) does not significantly influence the outcome. Clinicians should consider this when combining SDF with composite restorations.</p><p><strong>Clinical significance: </strong>Despite a reduction in bond strength, this study supports the use of SDF because of its therapeutic efficacy in arresting carious lesions in primary teeth, as different concentrations (12-38%) do not significantly affect composite bonding. SDF can be confidently used in minimally invasive pediatric care where long-term caries control is a priority.</p><p><strong>How to cite this article: </strong>Deka S, Chaudhary S, Manuja N, <i>et al.</i> Comparative Evaluation of the Effect of Different Concentrations of Silver Diamine Fluoride on the Shear Bond Strength of Composite Resin on Primary Tooth Dentin: An <i>In Vitro</i> Study. Int J Clin Pediatr Dent 2026;19(2):223-227.</p>","PeriodicalId":36045,"journal":{"name":"International Journal of Clinical Pediatric Dentistry","volume":"19 2","pages":"223-227"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protocol for Fabrication and Utilization of a Novel Chairside Technique for Interception of Tongue Thrusting Habit. 一种新的椅子旁技术的制作和应用方案,用于拦截舌头刺入习惯。
Q3 Dentistry Pub Date : 2026-02-01 Epub Date: 2026-02-12 DOI: 10.5005/jp-journals-10005-3409
Diksha V Wali, Hitesh Sawant, Ashwin Jawdekar, Parag V Gangurde

The importance of early interception of the tongue-thrusting habit need not be overemphasized. Among several habit-breaking appliances, few chairside methods are available among the gamut of habit-breaking appliances available. So, a novel chairside appliance technique was employed with the use of routinely used armamentarium like Begg's bracket, lock pin, and flowable composite. This paper describes the technique and its application alongside rapid maxillary expansion (RME) appliance in a 10-year-old female patient. The chairside technique was found to be simple and acceptable to the patient. This clinical technique was employed for the fabrication of a modified habit-breaking appliance for interception of tongue thrusting habit in a 10-year-old female patient with skeletal class III maxillomandibular relationship undergoing alternate rapid maxillary expansion and constriction (ALTRAMEC) and facemask therapy for correction of skeletal class III malocclusion. Incorporation of spikes in the bonded RME framework would have significantly affected the patient's compliance. This novel design strategically helped to reduce the wire framework and provide an easy chairside procedure using simple orthodontic armamentarium for habit interception, especially in patients who are already subjected to RME appliance or who refrain from such evidently visible habit-breaking appliance.

How to cite this article: Wali DV, Sawant H, Jawdekar A, et al. Protocol for Fabrication and Utilization of a Novel Chairside Technique for Interception of Tongue Thrusting Habit. Int J Clin Pediatr Dent 2026;19(2):250-254.

不需要过分强调早期拦截舌头推力习惯的重要性。在一些打破习惯的电器中,很少有椅子旁的方法在现有的打破习惯的电器中可用。因此,我们采用了一种新颖的椅子旁设备技术,使用了贝格支架、锁销和可流动复合材料等常规设备。本文介绍了该技术及其应用与快速上颌扩张器(RME)在一个10岁的女性病人。椅子旁技术被发现是简单的和可接受的病人。本临床技术用于制作一改良的习惯打破器,用于阻断舌突的习惯,用于10岁的女性III型上颌下颌关系患者,接受上颌快速交替扩张和收缩(altramc)和面罩治疗,矫正骨骼III型错颌。在绑定的RME框架中加入尖峰会显著影响患者的依从性。这种新颖的设计战略性地帮助减少了金属丝框架,并提供了一个简单的椅子边程序,使用简单的正畸器械来拦截习惯,特别是对于已经使用RME器械或避免使用这种明显可见的习惯打破器械的患者。本文引用方式:Wali DV, Sawant H, Jawdekar A,等。一种新的椅子旁技术的制作和应用方案,用于拦截舌头刺入习惯。中华临床儿科杂志,2016;19(2):250-254。
{"title":"Protocol for Fabrication and Utilization of a Novel Chairside Technique for Interception of Tongue Thrusting Habit.","authors":"Diksha V Wali, Hitesh Sawant, Ashwin Jawdekar, Parag V Gangurde","doi":"10.5005/jp-journals-10005-3409","DOIUrl":"10.5005/jp-journals-10005-3409","url":null,"abstract":"<p><p>The importance of early interception of the tongue-thrusting habit need not be overemphasized. Among several habit-breaking appliances, few chairside methods are available among the gamut of habit-breaking appliances available. So, a novel chairside appliance technique was employed with the use of routinely used armamentarium like Begg's bracket, lock pin, and flowable composite. This paper describes the technique and its application alongside rapid maxillary expansion (RME) appliance in a 10-year-old female patient. The chairside technique was found to be simple and acceptable to the patient. This clinical technique was employed for the fabrication of a modified habit-breaking appliance for interception of tongue thrusting habit in a 10-year-old female patient with skeletal class III maxillomandibular relationship undergoing alternate rapid maxillary expansion and constriction (ALTRAMEC) and facemask therapy for correction of skeletal class III malocclusion. Incorporation of spikes in the bonded RME framework would have significantly affected the patient's compliance. This novel design strategically helped to reduce the wire framework and provide an easy chairside procedure using simple orthodontic armamentarium for habit interception, especially in patients who are already subjected to RME appliance or who refrain from such evidently visible habit-breaking appliance.</p><p><strong>How to cite this article: </strong>Wali DV, Sawant H, Jawdekar A, <i>et al.</i> Protocol for Fabrication and Utilization of a Novel Chairside Technique for Interception of Tongue Thrusting Habit. Int J Clin Pediatr Dent 2026;19(2):250-254.</p>","PeriodicalId":36045,"journal":{"name":"International Journal of Clinical Pediatric Dentistry","volume":"19 2","pages":"250-254"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147379043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Evaluation of the Effect of Incorporating Varying Percentages of Microhydroxyapatite on the Compressive Strength and Microhardness of Resin-modified Glass Ionomer Cement: An In Vitro Study. 不同比例微羟基磷灰石对树脂改性玻璃离聚体水泥抗压强度和显微硬度影响的体外比较研究。
Q3 Dentistry Pub Date : 2026-02-01 Epub Date: 2026-02-12 DOI: 10.5005/jp-journals-10005-3361
Sonam Rajput, Bhavna Kaul, Shalan Kaul, Rumisa N Kashani, Manisha Koul, Syed Gulbar

Aim: This study was designed to investigate the impact of adding microhydroxyapatite (micro-HA) on the compressive strength and surface microhardness of resin-modified glass ionomer cement (RMGIC).

Materials and methods: A total of 60 specimens were prepared and equally distributed into four groups. The control group consisted of unmodified RMGIC, while in the experimental groups the RMGIC powder was modified by incorporating 1, 3, and 5% micro-HA, respectively, without altering the liquid component. All prepared samples were tested for compressive strength and microhardness, and the results obtained were statistically analyzed using one-way analysis of variance (ANOVA) followed by the Tukey's post hoc test to compare differences among the groups.

Results: RMGIC modified with 5% micro-HA showed the maximum compressive strength and microhardness.

Conclusion: The inclusion of micro-HA within RMGIC powder has been shown to enhance its mechanical properties.

How to cite this article: Rajput S, Kaul B, Kaul S, et al. Comparative Evaluation of the Effect of Incorporating Varying Percentages of Microhydroxyapatite on the Compressive Strength and Microhardness of Resin-modified Glass Ionomer Cement: An In Vitro Study. Int J Clin Pediatr Dent 2026;19(2):133-138.

目的:研究微羟基磷灰石(micro-HA)对树脂改性玻璃离子水泥(RMGIC)抗压强度和表面显微硬度的影响。材料和方法:共制备标本60例,平均分为4组。对照组为未经修饰的RMGIC,实验组分别加入1、3、5%的微ha对RMGIC粉末进行修饰,不改变其液体成分。对所有制备的样品进行抗压强度和显微硬度测试,并采用单因素方差分析(ANOVA)和Tukey事后检验对所得结果进行统计学分析,比较各组之间的差异。结果:经5%微羟基磷灰石修饰的RMGIC具有最大的抗压强度和显微硬度。结论:微羟基磷灰石在RMGIC粉末中掺入可提高其力学性能。如何引用本文:Rajput S, Kaul B, Kaul S等。不同比例微羟基磷灰石对树脂改性玻璃离聚体水泥抗压强度和显微硬度影响的体外比较研究。中华临床儿科杂志,2016;19(2):133-138。
{"title":"Comparative Evaluation of the Effect of Incorporating Varying Percentages of Microhydroxyapatite on the Compressive Strength and Microhardness of Resin-modified Glass Ionomer Cement: An <i>In Vitro</i> Study.","authors":"Sonam Rajput, Bhavna Kaul, Shalan Kaul, Rumisa N Kashani, Manisha Koul, Syed Gulbar","doi":"10.5005/jp-journals-10005-3361","DOIUrl":"10.5005/jp-journals-10005-3361","url":null,"abstract":"<p><strong>Aim: </strong>This study was designed to investigate the impact of adding microhydroxyapatite (micro-HA) on the compressive strength and surface microhardness of resin-modified glass ionomer cement (RMGIC).</p><p><strong>Materials and methods: </strong>A total of 60 specimens were prepared and equally distributed into four groups. The control group consisted of unmodified RMGIC, while in the experimental groups the RMGIC powder was modified by incorporating 1, 3, and 5% micro-HA, respectively, without altering the liquid component. All prepared samples were tested for compressive strength and microhardness, and the results obtained were statistically analyzed using one-way analysis of variance (ANOVA) followed by the Tukey's <i>post hoc</i> test to compare differences among the groups.</p><p><strong>Results: </strong>RMGIC modified with 5% micro-HA showed the maximum compressive strength and microhardness.</p><p><strong>Conclusion: </strong>The inclusion of micro-HA within RMGIC powder has been shown to enhance its mechanical properties.</p><p><strong>How to cite this article: </strong>Rajput S, Kaul B, Kaul S, <i>et al.</i> Comparative Evaluation of the Effect of Incorporating Varying Percentages of Microhydroxyapatite on the Compressive Strength and Microhardness of Resin-modified Glass Ionomer Cement: An <i>In Vitro</i> Study. Int J Clin Pediatr Dent 2026;19(2):133-138.</p>","PeriodicalId":36045,"journal":{"name":"International Journal of Clinical Pediatric Dentistry","volume":"19 2","pages":"133-138"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metagenomics as an Effective Diagnostic Approach for Exploring Oral Microbial Diversity and Dental Diseases: A Narrative Review. 宏基因组学作为探索口腔微生物多样性和口腔疾病的有效诊断方法:述评。
Q3 Dentistry Pub Date : 2026-02-01 Epub Date: 2026-02-12 DOI: 10.5005/jp-journals-10005-3413
Tarun Walia, Nikhil Srivastava, Raghavendra M Shetty, Vivek Rana
<p><strong>Aim and background: </strong>The oral cavity harbors a diverse microbiota that significantly influences oral health and disease. Conventional microbiological techniques have limitations in detecting the full range of microbial species, particularly those that are uncultivable. Metagenomics, through culture-independent, high-throughput sequencing methods, offers a comprehensive approach to studying oral microbial diversity. This narrative review aims to evaluate the role of metagenomics in exploring the oral microbiome and its association with dental diseases.</p><p><strong>Methods: </strong>This review systematically synthesized current literature and research on metagenomic technologies, including 16S ribosomal RNA (rRNA) sequencing, shotgun metagenomics, metatranscriptomics, metaproteomics, and metabolomics. It highlighted their principles, diagnostic capabilities, and limitations in analyzing microbial communities in caries, endodontic infections, and periodontitis. It also reviewed auxiliary tools such as quantitative polymerase chain reaction (qPCR), microarrays, fluorescence <i>in situ</i> hybridization (FISH), and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), and discussed the integration of artificial intelligence (AI) in metagenomic data interpretation.</p><p><strong>Results: </strong>Metagenomic studies have expanded the scope of known microbial species involved in dental caries beyond <i>Streptococcus mutans</i>, highlighting the contributions of <i>Lactobacillus</i>, <i>Veillonella</i>, <i>Actinomyces</i>, and <i>Candida albicans</i>. In endodontics, resistant species such as <i>Enterococcus faecalis</i>, <i>Porphyromonas endodontalis</i>, and <i>Fusobacterium nucleatum</i> are implicated in persistent infections. In periodontitis, a dysbiotic microbial shift has been associated with the presence of complex microbial consortia, including red and orange complex bacteria.</p><p><strong>Conclusion: </strong>Metagenomics is a powerful diagnostic tool that provides an in-depth characterization of the complex microbial ecosystem of the oral cavity. It offers diagnostic potential through early and accurate detection of pathogenic shifts, promotes personalized treatment planning, and opens avenues for the development of potential biomarkers of disease progression.</p><p><strong>Clinical significance: </strong>The integration of metagenomics into dental practice can revolutionize caries risk assessment, treatment precision, and disease prevention strategies. Although challenges such as high cost, data complexity, and lack of standardization remain, ongoing advancements in sequencing technologies and bioinformatics are expected to enhance its accessibility and clinical relevance.</p><p><strong>How to cite this article: </strong>Walia T, Srivastava N, Shetty RM, <i>et al.</i> Metagenomics as an Effective Diagnostic Approach for Exploring Oral Microbial Diversity and Dental Diseases: A Nar
目的与背景:口腔内有多种多样的微生物群,对口腔健康和疾病有重要影响。传统的微生物学技术在检测全范围的微生物物种方面存在局限性,特别是那些不可培养的微生物。宏基因组学通过培养独立的高通量测序方法,为研究口腔微生物多样性提供了全面的方法。本文旨在评价宏基因组学在探索口腔微生物组及其与口腔疾病的关系中的作用。方法:系统综合目前有关宏基因组技术的文献和研究成果,包括16S核糖体RNA (rRNA)测序、鸟枪宏基因组学、元转录组学、宏蛋白质组学、代谢组学等。它强调了他们的原理,诊断能力,以及在分析龋齿,牙髓感染和牙周炎的微生物群落方面的局限性。综述了定量聚合酶链反应(qPCR)、微阵列、荧光原位杂交(FISH)和基质辅助激光解吸/电离飞行时间质谱(MALDI-TOF MS)等辅助工具,并讨论了人工智能(AI)在宏基因组数据解释中的集成。结果:宏基因组学研究扩大了已知的与龋齿有关的微生物物种的范围,超越了变形链球菌,突出了乳杆菌、细孔菌、放线菌和白色念珠菌的贡献。在牙髓学中,粪肠球菌、牙髓卟啉单胞菌和核梭杆菌等耐药物种与持续感染有关。在牙周炎中,一种生态失调的微生物转移与复杂微生物联合体的存在有关,包括红色和橙色复杂细菌。结论:宏基因组学是一种强大的诊断工具,可以深入表征口腔复杂的微生物生态系统。它通过早期和准确检测致病转移提供了诊断潜力,促进了个性化治疗计划,并为开发疾病进展的潜在生物标志物开辟了道路。临床意义:将宏基因组学整合到牙科实践中可以彻底改变龋齿风险评估、治疗精度和疾病预防策略。尽管诸如高成本、数据复杂性和缺乏标准化等挑战仍然存在,但测序技术和生物信息学的持续进步有望提高其可及性和临床相关性。如何引用本文:Walia T, Srivastava N, Shetty RM等。宏基因组学作为探索口腔微生物多样性和口腔疾病的有效诊断方法:述评。中华临床儿科杂志,2016;19(2):278-284。
{"title":"Metagenomics as an Effective Diagnostic Approach for Exploring Oral Microbial Diversity and Dental Diseases: A Narrative Review.","authors":"Tarun Walia, Nikhil Srivastava, Raghavendra M Shetty, Vivek Rana","doi":"10.5005/jp-journals-10005-3413","DOIUrl":"10.5005/jp-journals-10005-3413","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Aim and background: &lt;/strong&gt;The oral cavity harbors a diverse microbiota that significantly influences oral health and disease. Conventional microbiological techniques have limitations in detecting the full range of microbial species, particularly those that are uncultivable. Metagenomics, through culture-independent, high-throughput sequencing methods, offers a comprehensive approach to studying oral microbial diversity. This narrative review aims to evaluate the role of metagenomics in exploring the oral microbiome and its association with dental diseases.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This review systematically synthesized current literature and research on metagenomic technologies, including 16S ribosomal RNA (rRNA) sequencing, shotgun metagenomics, metatranscriptomics, metaproteomics, and metabolomics. It highlighted their principles, diagnostic capabilities, and limitations in analyzing microbial communities in caries, endodontic infections, and periodontitis. It also reviewed auxiliary tools such as quantitative polymerase chain reaction (qPCR), microarrays, fluorescence &lt;i&gt;in situ&lt;/i&gt; hybridization (FISH), and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), and discussed the integration of artificial intelligence (AI) in metagenomic data interpretation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Metagenomic studies have expanded the scope of known microbial species involved in dental caries beyond &lt;i&gt;Streptococcus mutans&lt;/i&gt;, highlighting the contributions of &lt;i&gt;Lactobacillus&lt;/i&gt;, &lt;i&gt;Veillonella&lt;/i&gt;, &lt;i&gt;Actinomyces&lt;/i&gt;, and &lt;i&gt;Candida albicans&lt;/i&gt;. In endodontics, resistant species such as &lt;i&gt;Enterococcus faecalis&lt;/i&gt;, &lt;i&gt;Porphyromonas endodontalis&lt;/i&gt;, and &lt;i&gt;Fusobacterium nucleatum&lt;/i&gt; are implicated in persistent infections. In periodontitis, a dysbiotic microbial shift has been associated with the presence of complex microbial consortia, including red and orange complex bacteria.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Metagenomics is a powerful diagnostic tool that provides an in-depth characterization of the complex microbial ecosystem of the oral cavity. It offers diagnostic potential through early and accurate detection of pathogenic shifts, promotes personalized treatment planning, and opens avenues for the development of potential biomarkers of disease progression.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical significance: &lt;/strong&gt;The integration of metagenomics into dental practice can revolutionize caries risk assessment, treatment precision, and disease prevention strategies. Although challenges such as high cost, data complexity, and lack of standardization remain, ongoing advancements in sequencing technologies and bioinformatics are expected to enhance its accessibility and clinical relevance.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;How to cite this article: &lt;/strong&gt;Walia T, Srivastava N, Shetty RM, &lt;i&gt;et al.&lt;/i&gt; Metagenomics as an Effective Diagnostic Approach for Exploring Oral Microbial Diversity and Dental Diseases: A Nar","PeriodicalId":36045,"journal":{"name":"International Journal of Clinical Pediatric Dentistry","volume":"19 2","pages":"278-284"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the Effect of Breathing Exercise Using a Bubble Blower on Anxiety and Pain during Inferior Alveolar Nerve Block in Children Aged 6-10 Years: A Randomized Clinical Trial. 6-10岁儿童下肺泡神经阻滞时使用吹泡器呼吸运动对焦虑和疼痛的影响:一项随机临床试验
Q3 Dentistry Pub Date : 2026-02-01 Epub Date: 2026-02-12 DOI: 10.5005/jp-journals-10005-3412
Nirbhay Vashistha, Ambika S Rathore, Rinku Mathur, Tripti Sharma, Ruchika Bagaria, Rohit Barak

Background: Managing children's pain and anxiety during dental procedures is crucial, particularly when local anesthesia is required. Simple distraction techniques, such as breathing exercises (BEs), can help young patients cope with dental anxiety by redirecting their attention.

Aim: To evaluate the effect of BEs using a bubble blower on anxiety and pain during inferior alveolar nerve block (IANB) in children aged 6-10 years.

Materials and methods: Forty children (6-10 years old) requiring IANB were randomly divided into two groups. Group A practiced BEs with bubble blowers for one week, while group B received no intervention. Baseline anxiety [facial image scale (FIS)] and pulse rate were recorded. After 1 week, preprocedure anxiety was measured again, followed by a postprocedure pain assessment using the Face, Legs, Activity, Cry, Consolability (FLACC) scale and the Wong-Baker FACES Pain Scale (WBFPS).

Results: The intervention significantly reduced physiological and psychological stress during dental procedures. Pulse rate increased from 99.25 to 107.15 postinjection in group B, whereas decreased from 99.90 to 98.15 (p = 0.001) in group A. Anxiety levels (FIS scores) increased from 3.95 to 5.00 in group B but decreased from 3.90 to 2.55 in group A. Pain perception was lower in group A, with FLACC scores (4.55 vs 7.90) and WBFPS scores (5.20 vs 8.50).

Conclusion: BEs using a bubble blower effectively reduce anxiety and pain in children undergoing IANB, making it a valuable distraction technique.

Clinical significance: Anxiety and pain during IANB are common in pediatric dentistry and can affect a child's cooperation and future dental attitude. This study explores a simple, nonpharmacological method to improve the dental experience.

Clinical trial registration number: CTRI/2024/11/076166.

How to cite this article: Vashistha N, Rathore AS, Mathur R, et al. Evaluating the Effect of Breathing Exercise Using a Bubble Blower on Anxiety and Pain during Inferior Alveolar Nerve Block in Children Aged 6-10 Years: A Randomized Clinical Trial. Int J Clin Pediatr Dent 2026;19(2):183-189.

背景:在牙科手术过程中控制儿童的疼痛和焦虑是至关重要的,特别是当需要局部麻醉时。简单的分散注意力技巧,如呼吸练习(BEs),可以帮助年轻患者通过转移注意力来应对牙科焦虑症。目的:评价使用吹泡器的BEs对6 ~ 10岁儿童下牙槽神经阻滞(IANB)时焦虑和疼痛的影响。材料与方法:将40例6-10岁需要IANB的儿童随机分为两组。A组用吹泡泡机练习BEs 1周,B组不进行干预。记录基线焦虑[面部图像量表(FIS)]和脉搏率。1周后,再次测量术前焦虑,随后使用面部、腿部、活动、哭泣、安慰(FLACC)量表和Wong-Baker面部疼痛量表(WBFPS)进行术后疼痛评估。结果:干预显著降低了牙科治疗过程中的生理和心理压力。注射后B组脉搏率从99.25上升到107.15,而A组从99.90下降到98.15 (p = 0.001)。B组焦虑水平(FIS评分)从3.95上升到5.00,而A组从3.90下降到2.55。A组疼痛感觉较低,FLACC评分(4.55 vs 7.90)和WBFPS评分(5.20 vs 8.50)。结论:使用吹泡泡机的BEs可有效减轻IANB患儿的焦虑和疼痛,是一种有价值的分心技术。临床意义:IANB过程中的焦虑和疼痛在儿童牙科中很常见,并会影响儿童的合作和未来的牙科态度。本研究探索了一种简单的、非药物的方法来改善牙科体验。临床试验注册号:CTRI/2024/11/076166。如何引用本文:Vashistha N, Rathore AS, Mathur R等。6-10岁儿童下肺泡神经阻滞时使用吹泡器呼吸运动对焦虑和疼痛的影响:一项随机临床试验中华临床儿科杂志,2016;19(2):183-189。
{"title":"Evaluating the Effect of Breathing Exercise Using a Bubble Blower on Anxiety and Pain during Inferior Alveolar Nerve Block in Children Aged 6-10 Years: A Randomized Clinical Trial.","authors":"Nirbhay Vashistha, Ambika S Rathore, Rinku Mathur, Tripti Sharma, Ruchika Bagaria, Rohit Barak","doi":"10.5005/jp-journals-10005-3412","DOIUrl":"10.5005/jp-journals-10005-3412","url":null,"abstract":"<p><strong>Background: </strong>Managing children's pain and anxiety during dental procedures is crucial, particularly when local anesthesia is required. Simple distraction techniques, such as breathing exercises (BEs), can help young patients cope with dental anxiety by redirecting their attention.</p><p><strong>Aim: </strong>To evaluate the effect of BEs using a bubble blower on anxiety and pain during inferior alveolar nerve block (IANB) in children aged 6-10 years.</p><p><strong>Materials and methods: </strong>Forty children (6-10 years old) requiring IANB were randomly divided into two groups. Group A practiced BEs with bubble blowers for one week, while group B received no intervention. Baseline anxiety [facial image scale (FIS)] and pulse rate were recorded. After 1 week, preprocedure anxiety was measured again, followed by a postprocedure pain assessment using the Face, Legs, Activity, Cry, Consolability (FLACC) scale and the Wong-Baker FACES Pain Scale (WBFPS).</p><p><strong>Results: </strong>The intervention significantly reduced physiological and psychological stress during dental procedures. Pulse rate increased from 99.25 to 107.15 postinjection in group B, whereas decreased from 99.90 to 98.15 (<i>p</i> = 0.001) in group A. Anxiety levels (FIS scores) increased from 3.95 to 5.00 in group B but decreased from 3.90 to 2.55 in group A. Pain perception was lower in group A, with FLACC scores (4.55 vs 7.90) and WBFPS scores (5.20 vs 8.50).</p><p><strong>Conclusion: </strong>BEs using a bubble blower effectively reduce anxiety and pain in children undergoing IANB, making it a valuable distraction technique.</p><p><strong>Clinical significance: </strong>Anxiety and pain during IANB are common in pediatric dentistry and can affect a child's cooperation and future dental attitude. This study explores a simple, nonpharmacological method to improve the dental experience.</p><p><strong>Clinical trial registration number: </strong>CTRI/2024/11/076166.</p><p><strong>How to cite this article: </strong>Vashistha N, Rathore AS, Mathur R, <i>et al.</i> Evaluating the Effect of Breathing Exercise Using a Bubble Blower on Anxiety and Pain during Inferior Alveolar Nerve Block in Children Aged 6-10 Years: A Randomized Clinical Trial. Int J Clin Pediatr Dent 2026;19(2):183-189.</p>","PeriodicalId":36045,"journal":{"name":"International Journal of Clinical Pediatric Dentistry","volume":"19 2","pages":"183-189"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Assessment of a Newer Resin-based Bioactive Restorative Cement on Class II Cavities of Primary Molars: A Comparative Analysis. 一种新型树脂基生物活性修复体修复初级磨牙II类牙槽的临床评价:比较分析。
Q3 Dentistry Pub Date : 2026-02-01 Epub Date: 2026-02-12 DOI: 10.5005/jp-journals-10005-3415
Mohammed Bilal Sheriff K, Aarthi Jagadeesan, Arun Elangovan, Madhan Chenchugopal, Dharini Venkataraman, Packialakshmi Arumugam

Introduction: Primary molars play a significant role in mastication, jaw alignment, and guiding permanent tooth eruption. However, their proximal surfaces are prone to decay due to anatomical challenges and cleansing difficulties, making restorative intervention challenges. While traditional materials such as dental amalgam, composite resin (CR), and glass ionomer cement (GIC) are commonly used, advancements in dental technology have introduced bioactive materials as promising alternatives, warranting further research to ensure optimal outcomes.

Aim: The present study aimed to evaluate and compare the clinical performance of a newer resin-based bioactive restorative cement on class II cavities of primary molars over a 12-month period.

Materials and methods: A total of 258 class II restorations in primary molars of children aged 4-9 years were evaluated over 12 months. Three restorative materials-ACTIVA™ KIDS BioACTIVE™, Tetric N-Flow Bulk Fill Composite, and GC Gold Label 2-were assessed using modified USPHS criteria. The obtained values evaluated using the statistical software SPSS 21.0 revealed a p-value of ≤0.05, which was statistically significant.

Results: The frequency distribution of variables shows score A for all criteria except for color match at baseline and at 12 months, with no significant differences in outcomes within groups over time. However, group I demonstrated a significantly better color match compared to groups II [p = 0.04, relative risk (RR) 0.69] and III (RR 0.71), and had fewer teeth (2.3%) with score C for marginal discoloration.

Conclusion: ACTIVA™ KIDS BioACTIVE-RESTORATIVE™ demonstrated a significant difference in color match at 12 months compared to other groups, while no significant differences were observed among the three materials for other evaluated parameters.

Clinical significance: Moving forward toward biomimetic materials, ACTIVA™ KIDS BioACTIVE-RESTORATIVE™ is a promising material, with properties superior to that of composites and conventional GICs. Due to its remineralizing property and capability to accomplish bulk-fill restorations, it could be a great boon to pediatric dentists while performing class II restorations in primary molars.

How to cite this article: Mohammed Bilal Sheriff K, Aarthi J, Elangovan A, et al. Clinical Assessment of a Newer Resin-based Bioactive Restorative Cement on Class II Cavities of Primary Molars: A Comparative Analysis. Int J Clin Pediatr Dent 2026;19(2):210-214.

初生磨牙在咀嚼、下颌排列、引导恒牙萌出等方面起着重要的作用。然而,由于解剖学上的挑战和清洁困难,它们的近端表面容易腐烂,这给修复干预带来了挑战。虽然牙科汞合金、复合树脂(CR)和玻璃离子水泥(GIC)等传统材料是常用的,但牙科技术的进步已经引入了生物活性材料作为有前途的替代品,需要进一步研究以确保最佳结果。目的:本研究旨在评估和比较一种新型树脂基生物活性骨水泥在初级磨牙II类牙槽上12个月的临床表现。材料与方法:对258例4 ~ 9岁儿童初级磨牙ⅱ类修复体进行为期12个月的评估。采用改良的USPHS标准对三种修复材料activa™KIDS BioACTIVE™、Tetric N-Flow散装填充复合材料和GC Gold Label 2进行评估。用SPSS 21.0统计软件对所得值进行评价,p值≤0.05,具有统计学意义。结果:变量的频率分布显示,除了基线和12个月时的颜色匹配外,所有标准的得分都为A,随着时间的推移,各组间的结果没有显著差异。然而,与II组(p = 0.04,相对危险度(RR) 0.69)和III组(RR 0.71)相比,I组的牙齿颜色匹配明显更好,边缘变色得分为C的牙齿较少(2.3%)。结论:与其他组相比,ACTIVA™KIDS BioACTIVE-RESTORATIVE™在12个月时的颜色匹配方面存在显著差异,而在其他评估参数方面,三种材料之间无显著差异。临床意义:向仿生材料迈进,ACTIVA™KIDS BioACTIVE-RESTORATIVE™是一种很有前途的材料,其性能优于复合材料和传统的gic。由于其再矿化特性和完成填充修复的能力,它可能是一个伟大的福音,儿科牙医在进行II类修复的初级磨牙。本文摘自:Mohammed Bilal Sheriff K, Aarthi J, Elangovan A,等。一种新型树脂基生物活性修复体修复初级磨牙II类牙槽的临床评价:比较分析。中华临床儿科杂志,2016;19(2):210-214。
{"title":"Clinical Assessment of a Newer Resin-based Bioactive Restorative Cement on Class II Cavities of Primary Molars: A Comparative Analysis.","authors":"Mohammed Bilal Sheriff K, Aarthi Jagadeesan, Arun Elangovan, Madhan Chenchugopal, Dharini Venkataraman, Packialakshmi Arumugam","doi":"10.5005/jp-journals-10005-3415","DOIUrl":"10.5005/jp-journals-10005-3415","url":null,"abstract":"<p><strong>Introduction: </strong>Primary molars play a significant role in mastication, jaw alignment, and guiding permanent tooth eruption. However, their proximal surfaces are prone to decay due to anatomical challenges and cleansing difficulties, making restorative intervention challenges. While traditional materials such as dental amalgam, composite resin (CR), and glass ionomer cement (GIC) are commonly used, advancements in dental technology have introduced bioactive materials as promising alternatives, warranting further research to ensure optimal outcomes.</p><p><strong>Aim: </strong>The present study aimed to evaluate and compare the clinical performance of a newer resin-based bioactive restorative cement on class II cavities of primary molars over a 12-month period.</p><p><strong>Materials and methods: </strong>A total of 258 class II restorations in primary molars of children aged 4-9 years were evaluated over 12 months. Three restorative materials-ACTIVA™ KIDS BioACTIVE™, Tetric N-Flow Bulk Fill Composite, and GC Gold Label 2-were assessed using modified USPHS criteria. The obtained values evaluated using the statistical software SPSS 21.0 revealed a <i>p</i>-value of ≤0.05, which was statistically significant.</p><p><strong>Results: </strong>The frequency distribution of variables shows score A for all criteria except for color match at baseline and at 12 months, with no significant differences in outcomes within groups over time. However, group I demonstrated a significantly better color match compared to groups II [<i>p</i> = 0.04, relative risk (RR) 0.69] and III (RR 0.71), and had fewer teeth (2.3%) with score C for marginal discoloration.</p><p><strong>Conclusion: </strong>ACTIVA™ KIDS BioACTIVE-RESTORATIVE™ demonstrated a significant difference in color match at 12 months compared to other groups, while no significant differences were observed among the three materials for other evaluated parameters.</p><p><strong>Clinical significance: </strong>Moving forward toward biomimetic materials, ACTIVA™ KIDS BioACTIVE-RESTORATIVE™ is a promising material, with properties superior to that of composites and conventional GICs. Due to its remineralizing property and capability to accomplish bulk-fill restorations, it could be a great boon to pediatric dentists while performing class II restorations in primary molars.</p><p><strong>How to cite this article: </strong>Mohammed Bilal Sheriff K, Aarthi J, Elangovan A, <i>et al.</i> Clinical Assessment of a Newer Resin-based Bioactive Restorative Cement on Class II Cavities of Primary Molars: A Comparative Analysis. Int J Clin Pediatr Dent 2026;19(2):210-214.</p>","PeriodicalId":36045,"journal":{"name":"International Journal of Clinical Pediatric Dentistry","volume":"19 2","pages":"210-214"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Journal of Clinical Pediatric Dentistry
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1