{"title":"Aberrant methylation of CDKN2A, RASSF1A and WIF1 in sporadic adenocarcinomatous colorectal cancer: Associations with clinicopathological features","authors":"L. Vuong, Hung Nguyen, Van-Long Truong, Q. Nguyen","doi":"10.5455/jabet.2021.d131","DOIUrl":"https://doi.org/10.5455/jabet.2021.d131","url":null,"abstract":"","PeriodicalId":36275,"journal":{"name":"Journal of Advanced Biotechnology and Experimental Therapeutics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70795721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maqsud Hossain, Arittra Bhattacharjee, Tahmina Tabassum, Aura Rahman, Mohammad Tausiful Islam
{"title":"Prevalence and population biology of mastitis-causing Streptococcus uberis using an MLST based approach","authors":"Maqsud Hossain, Arittra Bhattacharjee, Tahmina Tabassum, Aura Rahman, Mohammad Tausiful Islam","doi":"10.5455/jabet.2021.d132","DOIUrl":"https://doi.org/10.5455/jabet.2021.d132","url":null,"abstract":"","PeriodicalId":36275,"journal":{"name":"Journal of Advanced Biotechnology and Experimental Therapeutics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70795761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Akter, M. Bhuiyan, K. Sujan, Z. Haque, S. Akter, M. Hossain, M. Islam
{"title":"Investigation of growth performance, lipid profile and liver histotexure of mice treated with butyric acid","authors":"M. Akter, M. Bhuiyan, K. Sujan, Z. Haque, S. Akter, M. Hossain, M. Islam","doi":"10.5455/jabet.2021.d140","DOIUrl":"https://doi.org/10.5455/jabet.2021.d140","url":null,"abstract":"","PeriodicalId":36275,"journal":{"name":"Journal of Advanced Biotechnology and Experimental Therapeutics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70795873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of different chronic respiratory diseases in terms of cigarette smoking: A hospital-based case control study on population of Bangladesh","authors":"Anindya Das, A. Sumit, Debasish Bhowmick","doi":"10.5455/JABET.2021.D130","DOIUrl":"https://doi.org/10.5455/JABET.2021.D130","url":null,"abstract":"","PeriodicalId":36275,"journal":{"name":"Journal of Advanced Biotechnology and Experimental Therapeutics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70795711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susan Nyawira Kimuni, S. Gitahi, E. Njagi, M. Ngugi
{"title":"Antinociceptive potential of methanol leaf extracts of Cissampelos parreira (Linn), Lantana camara (Linn) and Ocimum gratissimum (African basil)","authors":"Susan Nyawira Kimuni, S. Gitahi, E. Njagi, M. Ngugi","doi":"10.5455/jabet.2021.d135","DOIUrl":"https://doi.org/10.5455/jabet.2021.d135","url":null,"abstract":"","PeriodicalId":36275,"journal":{"name":"Journal of Advanced Biotechnology and Experimental Therapeutics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70795382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Das, M. Chowdhury, S. Akter, Apurbo Mondal, M. Uddin, Md Rahman, Md Rahman
Recently, Lumpy Skin Disease (LSD) has been portrayed as a terrifying threat to cattle in Southeast Asia. A lump like nodules in the external skin and mucous membrane with fever and swollen lymph nodes are the preliminary noticeable clinical signs of this devastating disease. It is commonly an arthropod-borne contagious illness, correspondingly the non-vector spreading through body discharge and infected fomites. The incubation period ranges from one to four weeks leading to viremia. A pronounced socio-economic collapse is driven by reduced quantity and quality of milk, udder infection, thinness, low quality hides, loss of draught power, abortion, infertility, limitation to meat ingestion, higher morbidity, etc. Animals of any age and gender are susceptible to the disease. The morbidity rate varies according to the immune status of animals and frequency of mechanical vectors. Primarily the disease was endemic in most SubSaharan regions of Africa, consequently extent to Middle East, Europe, and Asia. In the South-Eastern part of Asia, the disease has first been introduced in Bangladesh in July 2019 followed by China, India, Nepal, Bhutan, Vietnam, Hong Kong and Myanmar. Bangladesh recorded the maximum attack rate in Chattogram whereas at Cuttack in India. Particular vulnerable locations of other countries are yet to be confirmed. There is no epidemiological proceeding considering the present LSD situation report from rest of Asia. Strict quarantine, vector control, and prophylactic vaccine might be the best remedy for limiting the risk factors of the disease. Future studies should be directed towards determining the true burden of LSD on livestock and its potential risk factors with the perspective of geographic distributions. J Adv Biotechnol Exp Ther. 2021 Sep; 4(3): 322-333 eISSN: 2616-4760, https://doi.org/10.5455/jabet.2021.d133 Published by www.bsmiab.org
{"title":"An updated review on lumpy skin disease: a perspective of Southeast Asian countries","authors":"M. Das, M. Chowdhury, S. Akter, Apurbo Mondal, M. Uddin, Md Rahman, Md Rahman","doi":"10.5455/jabet.2021.d133","DOIUrl":"https://doi.org/10.5455/jabet.2021.d133","url":null,"abstract":"Recently, Lumpy Skin Disease (LSD) has been portrayed as a terrifying threat to cattle in Southeast Asia. A lump like nodules in the external skin and mucous membrane with fever and swollen lymph nodes are the preliminary noticeable clinical signs of this devastating disease. It is commonly an arthropod-borne contagious illness, correspondingly the non-vector spreading through body discharge and infected fomites. The incubation period ranges from one to four weeks leading to viremia. A pronounced socio-economic collapse is driven by reduced quantity and quality of milk, udder infection, thinness, low quality hides, loss of draught power, abortion, infertility, limitation to meat ingestion, higher morbidity, etc. Animals of any age and gender are susceptible to the disease. The morbidity rate varies according to the immune status of animals and frequency of mechanical vectors. Primarily the disease was endemic in most SubSaharan regions of Africa, consequently extent to Middle East, Europe, and Asia. In the South-Eastern part of Asia, the disease has first been introduced in Bangladesh in July 2019 followed by China, India, Nepal, Bhutan, Vietnam, Hong Kong and Myanmar. Bangladesh recorded the maximum attack rate in Chattogram whereas at Cuttack in India. Particular vulnerable locations of other countries are yet to be confirmed. There is no epidemiological proceeding considering the present LSD situation report from rest of Asia. Strict quarantine, vector control, and prophylactic vaccine might be the best remedy for limiting the risk factors of the disease. Future studies should be directed towards determining the true burden of LSD on livestock and its potential risk factors with the perspective of geographic distributions. J Adv Biotechnol Exp Ther. 2021 Sep; 4(3): 322-333 eISSN: 2616-4760, https://doi.org/10.5455/jabet.2021.d133 Published by www.bsmiab.org","PeriodicalId":36275,"journal":{"name":"Journal of Advanced Biotechnology and Experimental Therapeutics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70795780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Nobel, S. Akter, Ruksana Jebin, Titash Sarker, M. Rahman, Saad Zamane, Khairul Islam, Saima Sabrina, Nishat Akther, Ashekul Islam, M. Hasan, M. Islam
1Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail-1902, Bangladesh 2Department of Statistics, Mawlana Bhashani Science and Technology University, Santosh, Tangail-1902, Bangladesh 3Department of Biotechnology and Genetic Engineering, Mawlana Bhashani Science and Technology University, Santosh, Tangail-1902, Bangladesh 4Popular Diagnostic Centre, Mymensingh, Bangladesh
{"title":"Prevalence of multidrug resistance patterns of Escherichia coli from suspected urinary tract infection in Mymensingh city, Bangladesh","authors":"F. Nobel, S. Akter, Ruksana Jebin, Titash Sarker, M. Rahman, Saad Zamane, Khairul Islam, Saima Sabrina, Nishat Akther, Ashekul Islam, M. Hasan, M. Islam","doi":"10.5455/JABET.2021.D126","DOIUrl":"https://doi.org/10.5455/JABET.2021.D126","url":null,"abstract":"1Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail-1902, Bangladesh 2Department of Statistics, Mawlana Bhashani Science and Technology University, Santosh, Tangail-1902, Bangladesh 3Department of Biotechnology and Genetic Engineering, Mawlana Bhashani Science and Technology University, Santosh, Tangail-1902, Bangladesh 4Popular Diagnostic Centre, Mymensingh, Bangladesh","PeriodicalId":36275,"journal":{"name":"Journal of Advanced Biotechnology and Experimental Therapeutics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70795829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mushrooms are enriched with a plethora of bioactive molecules that play a vital role in the prevention of human diseases. The balance between ROS generation and cancer growth is one of the main prerequisites for efficient cancer treatment. In this study, to testify the aforesaid theory, five wild edible mushrooms were initially screened based on their anti-proliferative efficiency, and the best mushroom extract was selected for the assessment of their antioxidant potentialities in vitro in various artificially generated free radicals such as DPPH, ABTS+, and by FRAP experiment. The reason behind the antiproliferative potentiality and antioxidant capability of the most potent extract was also correlated by profiling its metabolites through GC-MS analysis. The study reveals, that the methanolic extract of Astraeus hygrometricus is the most potent anti-leukemic extract (IC50 22.7 ±0.23 μg/mL) followed by Serpula sp. (75.7 ±0.44 μg/mL), Phallus sp. (60.53±0.36 μg/mL), Tricholoma sp. (53.76±0.46 μg/mL), Lentinus sp. (58 ±0.13 μg/mL) against the Jurkat cell line with negligible effect on normal PBMC cells isolated from healthy donors. The assessment of the antioxidant profile Astraeus hygrometricus reveals its moderate antioxidant efficacy against several artificially generated free radicals, such as DPPH (76.9±0.16 μg/mL), ABTS+ (142±0.66 μg/mL) and moderate iron chelating efficacy (32.37±2.31μM). The GC-MS analysis of both methanol and ethyl acetate extracts of Astraeus hygrometricus have found 53 and 52 compounds respectively, with wide diverse ranges of chemically classified biomolecules such as alkane, alcohol, fatty acid, organic acid, polycyclic and heterocyclic compounds, amino acid, vitamin, and hormone, etc. with a wide array of biological activity such as anticancer and antioxidant potentiality. In conclusion, it can be said that these wild edible mushroom Astraeus hygrometricus are a repository of novel biomolecules that can be used in the treatment of Leukemia in the future.
{"title":"Assessment of the anti-leukemic and antioxidant potential of the methanol extract of a wild, edible, and novel mushroom, Astraeus hygrometricus, and unraveling its metabolomic profile.","authors":"Amrita Pal, Ribhu Ray, K. Acharya, Santanu Paul","doi":"10.5455/jabet.2021.d138","DOIUrl":"https://doi.org/10.5455/jabet.2021.d138","url":null,"abstract":"Mushrooms are enriched with a plethora of bioactive molecules that play a vital role in the prevention of human diseases. The balance between ROS generation and cancer growth is one of the main prerequisites for efficient cancer treatment. In this study, to testify the aforesaid theory, five wild edible mushrooms were initially screened based on their anti-proliferative efficiency, and the best mushroom extract was selected for the assessment of their antioxidant potentialities in vitro in various artificially generated free radicals such as DPPH, ABTS+, and by FRAP experiment. The reason behind the antiproliferative potentiality and antioxidant capability of the most potent extract was also correlated by profiling its metabolites through GC-MS analysis. The study reveals, that the methanolic extract of Astraeus hygrometricus is the most potent anti-leukemic extract (IC50 22.7 ±0.23 μg/mL) followed by Serpula sp. (75.7 ±0.44 μg/mL), Phallus sp. (60.53±0.36 μg/mL), Tricholoma sp. (53.76±0.46 μg/mL), Lentinus sp. (58 ±0.13 μg/mL) against the Jurkat cell line with negligible effect on normal PBMC cells isolated from healthy donors. The assessment of the antioxidant profile Astraeus hygrometricus reveals its moderate antioxidant efficacy against several artificially generated free radicals, such as DPPH (76.9±0.16 μg/mL), ABTS+ (142±0.66 μg/mL) and moderate iron chelating efficacy (32.37±2.31μM). The GC-MS analysis of both methanol and ethyl acetate extracts of Astraeus hygrometricus have found 53 and 52 compounds respectively, with wide diverse ranges of chemically classified biomolecules such as alkane, alcohol, fatty acid, organic acid, polycyclic and heterocyclic compounds, amino acid, vitamin, and hormone, etc. with a wide array of biological activity such as anticancer and antioxidant potentiality. In conclusion, it can be said that these wild edible mushroom Astraeus hygrometricus are a repository of novel biomolecules that can be used in the treatment of Leukemia in the future.","PeriodicalId":36275,"journal":{"name":"Journal of Advanced Biotechnology and Experimental Therapeutics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70796231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of optimum dietary inclusion level of probiotics for potential benefits on intestinal histomorphometry, microbiota, and pH in Japanese Quails","authors":"M. Afrin, M. Sachi, M. Meher, N. Jahan","doi":"10.5455/JABET.2021.D127","DOIUrl":"https://doi.org/10.5455/JABET.2021.D127","url":null,"abstract":"","PeriodicalId":36275,"journal":{"name":"Journal of Advanced Biotechnology and Experimental Therapeutics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70795840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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