中华放射医学与防护杂志最新文献

{"title":"Dosimetric impacts of Utrecht applicator on three-dimensional brachytherapy for advanced cervical carcinoma","authors":"T. Xue, Yunchuan Sun","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.11.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.11.007","url":null,"abstract":"Objective \u0000To investigate the effect of Utrecht applicator on dosimetrics of targets and OARs in brachytherapy for advanced cervical cancer. \u0000 \u0000 \u0000Methods \u0000Data of patients with locally advanced cervical cancer who received brachytherapy with Utrecht Source Applicator from 2017 to 2018 in the Department of Radiotherapy, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Hebei province, were collected. The original plan was intracavitary /interstitial brachytherapy (IC/IS-BT). With the original contour and prescription dose unchanged, the implantation was removed and new intracavitary brachytherapy (IC) plan was designed. The dosimetric parameters of IC/IS plan and IC plan were compared and analyzed, and the effect of IS implantation on dose was evaluated. \u0000 \u0000 \u0000Results \u0000The D90 of HR-CTV was (88.68±1.84) Gy in IC/IS group and (85.54±0.54) Gy in IC group, with significant difference(t=6.200, P 0.05). \u0000 \u0000 \u0000Conclusions \u0000For the brachytherapy of locally advanced cervical cancer, the use of Utrecht Source Applicator can satisfy the prescription dose coverage. Adding IS insertion needle can improve the optimization space of the plan. Without exceeding the dose limit of OAR, the radiation dose to HR-CTV can be significantly increased, and the uniformity of dose distribution can be improved as well. \u0000 \u0000 \u0000Key words: \u0000Cervical cancer; Brachytherapy; Utrecht applicator; Dosimetry","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"12 1","pages":"837-840"},"PeriodicalIF":0.0,"publicationDate":"2019-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89736653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse events and prognosis analysis in 422 cervical cancer patients after intensity modulated radiation therapy combined with brachytherapy","authors":"Jian Wang, Lijun Hu, Boyu Yu, Jingping Yu, Lili Wang, X. Ni, Q. Meng, Zhiqiang Sun, Jianlin Wang, B. Nie","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.11.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.11.002","url":null,"abstract":"Objective \u0000To investigate the adverse events and efficacy in cervical cancer patients receiving intensity modulated radiationtherapy (IMRT) plusbrachytherapy with or without chemotherapy, and to indentify the factors that may affect the prognosis. \u0000 \u0000 \u0000Methods \u0000In this retrospective analysis, we analyzed the clinical and follow-up data of the 422 cervical cancer patients, who received IMRT plus brachytherapy with or without chemotherapy.Among these patients, 353 cases received concurrent chemoradiotherapy and the other 69 cases received radiotherapy alone. Kaplan-Meier method was utilized to calculate the overall survival (OS) rates. Log-rank-test and Cox regression were performed to executing the univariate and multivariate analysis of the OS, respectively. \u0000 \u0000 \u0000Results \u0000The rate of complete response (CR) in the patients receiving concurrent chemoradiotherapy was significantly higher than that of the patients who received single radiotherapy (77.6% vs. 65.2%, χ2=4.812, P 0.05). The OS for the patients receiving prophylactic extended field irradiation of the PALN was higher than that of patients without prophylactic radiation (χ2=3.953, P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Cervical cancer patients receiving IMRT plus brachytherapy with or without chemotherapy had achieved promising prognosis. Prophylactic extended field irradiation of the PALN contributed to the improved OS in the patients with pelvic lymph node metastasis. FIGO staging, pathology type, lymph node metastasis, radiotherapy concurrent with chemotherapy or not, and short-term efficiency were independent factors for the prognosis. \u0000 \u0000 \u0000Key words: \u0000Cervical cancer; Radiotherapy; Brachytherapy; Chemotherapy; Prognosis","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"45 1","pages":"807-812"},"PeriodicalIF":0.0,"publicationDate":"2019-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84190569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison in precision of image registration between MRI simulation and diagnostic MRI with CT simulation","authors":"Gu Ying, Xing Pengfei, Cai Shang, Qian Jianjun, Fan Qiuhong, T. Ye","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.11.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.11.005","url":null,"abstract":"Objective \u0000To evaluate the precision of image registration between MRI simulation (MRIsim) and CT simulation compared to diagnostic MRI(MRIdiag) and to provide information for further application of MRIsim. \u0000 \u0000 \u0000Methods \u0000A total of 24 patients who underwent both MRIsim and MRIdiag were enrolled, including 8 patients with gliomas, 8 with nasopharyngeal carcinomas and 8 with prostate cancers. MRIsim and MRIdiag images of each patient were fused with CT. The OARs were delineated on three modalities of images and targets were delineated on fusion image of MRIsim with CT (F_CTMsim) and fusion image of MRIdiag with CT (F_CTMdiag) respectively. The concordance index (CI), Dice′s similarity coefficient (DSC) between the OARs and image similarity index (S) based on images from MRIsim, MRIdiag and CT were evaluated. IMRT plans were designed based targets on F_CTMsim and OARs on CT images, and differences in dosimetry of targets and OARs were evaluated subsequently. \u0000 \u0000 \u0000Results \u0000Volumes of most OAR from three modalities of images showed no statistically significant difference(P>0.05). All the CI and DSC between the OARs derived from MRIsim and CT were higher than those corresponding values from MRIdiag, and a statistically significant difference was achieved in 50% of these OARs (t=2.58-5.47, P 0.05). \u0000 \u0000 \u0000Conclusions \u0000The precision of image registration can be significantly improved by introducing MRIsim into radiotherapy planning design compared with MRIdiag. However, no significant differences in dosimetry were found on targets produced by rigid registration and manual adjustment method . \u0000 \u0000 \u0000Key words: \u0000MRI simulation; Image fusion; Rigid registration; MRI diagnosis; Precision","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"121 1","pages":"827-832"},"PeriodicalIF":0.0,"publicationDate":"2019-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83357421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary application of 192 Ir high-dose rate brachytherapy in postoperative recurrent colorectal cancer with intrapulmonary oligometastases","authors":"Yin Xiaoming, Sun Yun-chuan, H. Tingting, He Xinying, Bi Jianqiang, Xiao Li, Huang Rujing, Lu Hongling, Wang Junjie","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.11.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.11.006","url":null,"abstract":"Objective \u0000To investigate the efficacy and feasibility of 192Ir high-dose rate brachytherapy for recurrent intrapulmonary oligometastasis after colorectal cancer surgery. \u0000 \u0000 \u0000Methods \u0000Patients from May 2013 to October 2017 with intrapulmonary oligometastasisafter colorectal cancer surgery in Cangzhou Integrated Traditional Chinese and Western Medicine Hospital were enrolled. A total of 15 lesions were obtained from 10 patients, which were treated with CT-guided high dose rate of 192Ir. The implant needles were inserted into the tumor and were adjusted to appropriate positions under the guidance of CT. Then the images after transplanting were uploaded to the planning system to delineate the target area and the organ at risk volume. Patients underwent a single radiation dose of 20 Gy. \u0000 \u0000 \u0000Results \u0000All 10 patients were successfully treated. Grade 1 adverse events were observed for 30% of patients. Of the 10 patients, one patient had a mild cough, and two had bloody sputum. There was no serious adverse events occurred. The local control rate (LC) of the patients at 1 year after treatment was achieved in 93.3%. Only one developed local advancement after six months, who received the secondary brachytherapy. The median progression-free survival(PFS) was 8.5 months and the median overall survival(OS) was 14.7 months. \u0000 \u0000 \u0000Conclusions \u0000High dose rate brachytherapy is effective in terms of recurrent lung metastases after surgery for colorectal cancer, with a moderate rate of adverse reactions and a favorable local tumor control rate. \u0000 \u0000 \u0000Key words: \u0000Colorectal cancer; Lung metastasis; High dose ratebrachytherapy; 192Ir","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"96 1","pages":"833-836"},"PeriodicalIF":0.0,"publicationDate":"2019-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87958119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation and analysis on current status of radiation protection in 58 primary medical institutions in Xi′an city","authors":"Sun Leihuan, Wu Wenjing, Zhang Bin, Zhang Chao","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.11.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.11.009","url":null,"abstract":"Objective \u0000To survey the current situation of radiological protection in primary medical institutions in Xi′an, analyze the existing problems, and provide countermeasures and suggestions for further strengthening the radiological protection management of radiological diagnosis and treatment in primary medical institutions. \u0000 \u0000 \u0000Methods \u0000A total of 58 primary medical institutions in Xi′an were selected by stratified cluster sampling according to the work plan of national radiological health monitoring project and the related implementation plan in Shaanxi province. Data were collected by using a unified design questionnaire to investigate and analyze the basic protection situation, radiological diagnosis and treatment equipment, protective auxiliary equipment and their use situations as well as the standardization of the machine room of these radiological diagnosis and treatment institutions. Protective monitoring of the machine room was conducted by the Radiological Health Department of Xi′an CDC together with the relevant data being recorded. \u0000 \u0000 \u0000Results \u0000The survey found that the holding rate of the license of radiological diagnosis and treatment in primary medical institutions was 96.6%, the ratio of professional and technical workers with professional expertise in radiological diagnosis and treatment 89.6%, the training rate of radiological staff 89.6%, and the proportion of protective equipment 85.7%, the utilization rate of protective equipment 74.3%, the rate of physical examination for radiation workers 91.4%, and the rate of personal dose monitoring 96.5%. There was no statistically significance in the area and at the shortest side of the machine rooms between different types(P>0.05). There were statistically significances in ventilation (χ2=7.034, P<0.05), tidiness (χ2=29.075, P<0.05), warning sign equipment (χ2=23.156, P<0.05) and status indicator light equipment (χ2=23.478, P<0.05) between different types of primary medical institutions. The qualified rate of radiation protection in the workplace of the radiological diagnosis and treatment institutions was 74.1%, and the difference in radiation dose levels in the surrounding environment of the workplace of the radiological diagnosis and treatment institutions between different types was statistically significant (χ2=14.028, P<0.05). \u0000 \u0000 \u0000Conclusions \u0000The patients′personal protective equipment allocation rate and the utilization rate of examined individuals′ protective equipment in the primary medical institutions are low, the standardization of the radiation workplace is poor, and the radiation protection in the workplace needs to be improved. \u0000 \u0000 \u0000Key words: \u0000Primary medical institutions; Radiological protection; Investigation","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"13 1","pages":"847-851"},"PeriodicalIF":0.0,"publicationDate":"2019-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81593432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monitoring and analysis of gross α and gross β levels in drinking water sources in Guangdong province","authors":"J. Zou, Fan Cui, Yanbing Liu, Shanyu Zhou, Yuxin Jia","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.11.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.11.008","url":null,"abstract":"Objective \u0000To investigate the distribution of gross α and gross β radioactive levels in drinking raw water from different regions of Guangdong province, and to establish the radioactive level base line value in raw water. \u0000 \u0000 \u0000Methods \u0000The samples from 191 drinking water sources in use in Guangdong province were collected in rainy season and dry season, respectively, and determined and analyzed under the standard examination method for drinking water-radiological parameters (GB/T 5750.13-2006). The levels of gross α and gross β radioactivity were evaluated under the standard for drinking water quality (GB 5749-2006). \u0000 \u0000 \u0000Results \u0000A total of 377 raw water samples were taken, including 189 samples in rainy season and 188 samples in dry season, in which 186 samples were matched between rainy season and dry season. In dry season, the gross α levels ranged from 0.008 Bq/L to 0.582 Bq/L, averaged at (0.034±0.060) Bq/L, while the gross β levels ranged from 0.014 Bq/L to 0.637 Bq/L, averaged at (0.108±0.091) Bq/L. In rainy season, the gross α levels ranged from 0.008 Bq/L to 0.402 Bq/L, averaged at (0.045±0.064) Bq/L, while the gross β levels ranged from 0.014 Bq/Lto 0.848 Bq/L, averaged at (0.125±0.128) Bq/L. The gross α and gross β radioactivity levels of other samples were much lower than the guidance values in the national radioactivity standards on drinking water radioactivity, except for a sample from Shanwei area. The gross α and gross β radioactivity levels in the rainy season were higher than in the dry water season, and the gross α radioactivity levels in the rainy season were significantly higher than in the dry water season. There were significant differences in gross α and gross β radioactivity levels in rainy(Frainy season=1.819, 2.709, P<0.05) and dry season (Fdry season=1.985, 8.461, P<0.05)in different water systems, and the levels of gross α and gross β radioactivity in the rivers in western Guangdong were the highest. The gross α and gross β radioactivity levels of groundwater in rainy season were higher than in river water and lake water, and the gross α and gross β radioactivity levels in river water were higher than in lake and reservoir water, with the statistically significant differences(Ftotal α=39.323, Ftotal β=25.911, P<0.05), the gross α and gross β radioactivity levels in dry season were higher than in river water and lake water, with the statistically significant difference(Ftotal α=11.520, Ftotal β=28.435, P<0.05). The highest radioactivity levels is in groundwater, followed by river water, and the lowest is in lake and reservoir water. \u0000 \u0000 \u0000Conclusions \u0000The natural radioactivity background levels in drinking raw water in Guangdong province is lower than the limit value on drinking water stipulated by our country. The radioactivity levels in raw water in western Guangdong is significantly higher than in other water systems, and the radioactivity level in river water is also significantly higher than in lake and reservoir ","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"20 1","pages":"841-846"},"PeriodicalIF":0.0,"publicationDate":"2019-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80532383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of CT artifact on calculation of radiotherapy dose","authors":"Ruisong Guo, Xiaofen Xing, T. Cui, Jun Zhang, Ji-Xia Pen","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.11.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.11.013","url":null,"abstract":"Objective \u0000To investigate the effect of simple artifacts on the calculation of radiation dose in actual clinical operations by the aid of artificially caused CT artifacts. \u0000 \u0000 \u0000Methods \u0000The phantom was scanned using CT before and after replacing the titanium alloy component. Then, the CT values were measured at different distances before and after replacement. After correcting the CT value of the titanium alloy region to the CT value of the water phantom, the doses to the phantom were calculated by using Varian′s AAA algorithm, AXB algorithm and Pinnacle system′s CCC algorithm. The absolute dose values at different distances were furtherly analyzed. \u0000 \u0000 \u0000Results \u0000Varian system was consistent with Pinnacle system in evaluating the CT values. When the CT value deviated by less than 30 HU for a uniform phantom, the dose deviations of the three different algorithms were within 6.0 %-12.0 % at a distance of 0.5 cm from the body surface, and less than 1.0% at a distance of more than 1.5 cm from the body surface. When the CT value deviated by 15 HU for the lung phantom, both Varian′s AAA algorithm and Varian′s AXB algorithm showed about 1.0% dose deviation. However, the CCC algorithm of the Pinnacle system had a significant difference (5.0%) in dose values under the same conditions. \u0000 \u0000 \u0000Conclusions \u0000CT artifacts have noticeable effects on the calculation of radiation dose and change tissue dose distribution which may result in insufficient or excessive exposure doses. \u0000 \u0000 \u0000Key words: \u0000CT artifact; Titanium alloy; Dose; Algorithm; Treatment planning system","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"69 1","pages":"870-873"},"PeriodicalIF":0.0,"publicationDate":"2019-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76570069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}