Ö. Çelebi, S. Başer, M. Güler, Demet Çelebi, Selahattin Çelebi̇
Objective: The aim of this study is to detect St. John's Wort, Nigella sativa, Clove, Orange Peel and Garlic oil on bacteria isolated from blood culture to determine its antibacterial effect. Methods: One hundered blood samples sent to … Medical Microbiology Laboratory between 1 June 2021 and 1 January 2022 were analyzed with blood culture system. Bacteria isolated from blood culture were passaged into blood agar. Bacterial suspension was prepared from the bacterial colonies at 0.5 Mc Farland turbidity. In order to determine the antibacterial activity of plant extract oils, Minimum Inhibition Concentration and Minimal Bactericidal Concentration values were determined by liquid microdilution method. Also, the zone diameters of the disc diffusion method were measured. Results: The antibacterial effect of plant extract oils was detected on only 10 of the 100 clinical samples included in the study. St. John's Wort oil used in these 10 samples showed the most effective antibacterial effect of 7.81 µg/mL against Staphylococcus haemolyticus and Enterobacter aerogenes. Garlic oil showed the most effective antibacterial effect against Escherichia coli and Staphylococcus haemolyticus at 7.81 µg/mL. Nigella sativa oil showed the most effective antibacterial effect against Staphylococcus haemolyticus at 3.9 µg/mL. Orange Peel oil showed the most effective antibacterial effect against Enterococcus faecalis at 1.95 µg/mL. The minimum inhibition concentration at which the oils were effective on microorganisms was determined by comparing them with standard control strains. Conclusion: More clinical isolates and high-dose studies are needed to determine the effectiveness of plant extract oils. Garlic oil Escherichia coli, Staphylococcus haemolyticus and Enterobacter aerogenes, St. John's wort oil Staphylococcus haemolyticus and Enterobacter aerogenes, Nigella sativa) oil on Staphylococcus haemolyticus has been found to be effective
{"title":"Determination of antibacterial activity of St. John's Wort (Hypericum perforatum L.) oil, Nigella sativa oil, Clove (Eugenia caryophyllata) oil, Orange Peel (Citrus sinensis) and Garlic (Allium sativa) oil against microorganisms isolated from clinical samples","authors":"Ö. Çelebi, S. Başer, M. Güler, Demet Çelebi, Selahattin Çelebi̇","doi":"10.56766/ntms.1177132","DOIUrl":"https://doi.org/10.56766/ntms.1177132","url":null,"abstract":"Objective: The aim of this study is to detect St. John's Wort, Nigella sativa, Clove, Orange Peel and Garlic oil on bacteria isolated from blood culture to determine its antibacterial effect. \u0000Methods: One hundered blood samples sent to … Medical Microbiology Laboratory between 1 June 2021 and 1 January 2022 were analyzed with blood culture system. Bacteria isolated from blood culture were passaged into blood agar. Bacterial suspension was prepared from the bacterial colonies at 0.5 Mc Farland turbidity. In order to determine the antibacterial activity of plant extract oils, Minimum Inhibition Concentration and Minimal Bactericidal Concentration values were determined by liquid microdilution method. Also, the zone diameters of the disc diffusion method were measured. \u0000Results: The antibacterial effect of plant extract oils was detected on only 10 of the 100 clinical samples included in the study. St. John's Wort oil used in these 10 samples showed the most effective antibacterial effect of 7.81 µg/mL against Staphylococcus haemolyticus and Enterobacter aerogenes. Garlic oil showed the most effective antibacterial effect against Escherichia coli and Staphylococcus haemolyticus at 7.81 µg/mL. Nigella sativa oil showed the most effective antibacterial effect against Staphylococcus haemolyticus at 3.9 µg/mL. Orange Peel oil showed the most effective antibacterial effect against Enterococcus faecalis \u0000at 1.95 µg/mL. The minimum inhibition concentration at which the oils were effective on microorganisms was determined by comparing them with standard control strains. \u0000Conclusion: More clinical isolates and high-dose studies are needed to determine the effectiveness of plant extract oils. Garlic oil Escherichia coli, Staphylococcus haemolyticus and Enterobacter aerogenes, St. John's wort oil Staphylococcus haemolyticus and Enterobacter aerogenes, Nigella sativa) oil on Staphylococcus haemolyticus has been found to be effective","PeriodicalId":371755,"journal":{"name":"New Trends in Medicine Sciences","volume":"161 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124498977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmet Veli Sanibas, F. Çakmak, I. Baydar, D. Binici
Aim: In this study, the Turkish version of the American Diabetes Association (ADA) prediabetes risk test and the 75-g oral glucose tolerance test (OGTT) were administered to patients to determine the rate of prediabetic patients in our geographical region and investigate its consistency with the ADA risk test. In addition, the presence of retinopathy in prediabetic patients was examined. Material and Method: The study included a total of 342 patients with a fasting plasma glucose value of 100-125 mg/dl. The 75-g OGTT test was performed on the patients. The ADA prediabetes risk test was also administered, and the scores were noted. The OGTT and risk test results were compared. According to the ADA prediabetes risk test, the patients were classified into those at risk for type 2 diabetes mellitus (DM) and those diagnosed with prediabetes. In the evaluation of retinopathy, visual acuity, intraocular pressure measurement, and anterior segment and fundus examinations were performed in each patient. The data of the patients were compared with statistical analysis methods. Results: When the OGTT results of the patients with negative ADA prediabetes risk test scores were compared, the sensitivity was determined as 54% and the specificity as 63% (p0.05). There was no retinopathy finding in the eye examination of 262 of the 342 patients included in the study (p>0.05). Conclusion: In this study, we found that a positive ADA prediabetes risk score was effective in predicting prediabetes, but it was not sufficient. However, prediabetes diagnosed according to OGTT was found to be higher in the patients with negative test scores. Therefore, the prediabetes risk test was not effective in predicting prediabetes among the patients with negative scores.
目的:本研究采用土耳其版美国糖尿病协会(ADA)前驱糖尿病危险试验和75 g口服葡萄糖耐量试验(OGTT)对患者进行检测,以确定我国地理区域内糖尿病前驱患者的发生率,并探讨其与ADA危险试验的一致性。此外,还检查了糖尿病前期患者是否存在视网膜病变。材料与方法:本研究共纳入342例空腹血糖值为100-125 mg/dl的患者。对患者进行75 g OGTT试验。同时进行ADA前驱糖尿病风险测试,并记录得分。比较OGTT和风险测试结果。根据ADA前驱糖尿病危险试验,将患者分为2型糖尿病(DM)危险组和诊断为前驱糖尿病的患者。在评估视网膜病变时,对每位患者进行了视力、眼压测量、前段和眼底检查。采用统计学分析方法对患者资料进行比较。结果:比较ADA前驱糖尿病危险测试评分阴性患者OGTT结果,确定敏感性为54%,特异性为63% (p0.05)。342例患者中有262例眼科检查未发现视网膜病变(p>0.05)。结论:在本研究中,我们发现ADA前驱糖尿病风险评分阳性对预测前驱糖尿病是有效的,但并不充分。然而,根据OGTT诊断的前驱糖尿病在测试分数为阴性的患者中被发现更高。因此,前驱糖尿病风险测试在得分为负的患者中不能有效预测前驱糖尿病。
{"title":"INVESTIGATION OF THE EFFECTIVENESS OF THE ADA PREDIABETES RISK TEST IN IDENTIFYING PREDIABETIC TURKISH PATIENTS AND DETERMINATION OF THE FREQUENCY OF RETINOPATHY IN PREDIABETIC PATIENTS","authors":"Ahmet Veli Sanibas, F. Çakmak, I. Baydar, D. Binici","doi":"10.56766/ntms.1161735","DOIUrl":"https://doi.org/10.56766/ntms.1161735","url":null,"abstract":"Aim: In this study, the Turkish version of the American Diabetes Association (ADA) prediabetes risk test and the 75-g oral glucose tolerance test (OGTT) were administered to patients to determine the rate of prediabetic patients in our geographical region and investigate its consistency with the ADA risk test. In addition, the presence of retinopathy in prediabetic patients was examined. \u0000Material and Method: \u0000The study included a total of 342 patients with a fasting plasma glucose value of 100-125 mg/dl. The 75-g OGTT test was performed on the patients. The ADA prediabetes risk test was also administered, and the scores were noted. The OGTT and risk test results were compared. According to the ADA prediabetes risk test, the patients were classified into those at risk for type 2 diabetes mellitus (DM) and those diagnosed with prediabetes. In the evaluation of retinopathy, visual acuity, intraocular pressure measurement, and anterior segment and fundus examinations were performed in each patient. The data of the patients were compared with statistical analysis methods. \u0000Results: When the OGTT results of the patients with negative ADA prediabetes risk test scores were compared, the sensitivity was determined as 54% and the specificity as 63% (p0.05). There was no retinopathy finding in the eye examination of 262 of the 342 patients included in the study (p>0.05). \u0000Conclusion: In this study, we found that a positive ADA prediabetes risk score was effective in predicting prediabetes, but it was not sufficient. However, prediabetes diagnosed according to OGTT was found to be higher in the patients with negative test scores. Therefore, the prediabetes risk test was not effective in predicting prediabetes among the patients with negative scores.","PeriodicalId":371755,"journal":{"name":"New Trends in Medicine Sciences","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132085131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Behcet Varışlı, Canan Akman, S. Yildirim, Kenan Atac, O. Çakır
Introduction: Drug intoxications may be associated with accidental or suicidal ingestion of toxic agents. In both cases, emergency treatment includes administration of the relevant antidote and gastric decontamination. If necessary, patients are followed up in wards and intensive care units, whereas a group of patients are discharged directly from the emergency department. Materials and Methods: The aim of this study was to conduct a retrospective evaluation of examination findings, laboratory investigations, duration of treatments, psychiatric follow-up studies, hospitalization rates and mortality rates in patients admitted to our emergency department due to drug intoxication between 2017 and 2018. Results: Of the 126 patients included in our study, 83 were female, with a mean age of 33.58 ± 13.58 years and a range of 18 to 92 years. Of all patients, 76 were hospitalized in the ward and 1 in the intensive care unit, while 49 were treated in the emergency department. One patient had mortality on the eighth day of hospitalization. Eighty-six patients had been on psychiatric treatment prior to admission, whereas 82 patients were referred to the psychiatry department after admission. The rate of psychiatric consultation was significantly higher in patients who were hospitalized in any department due to drug intoxication than in patients who were discharged directly from the emergency department (p
{"title":"Evaluation of Patients Admitted To The Emergency Service Due To Poisoning İn Terms of Antidote Use and Decontamination Practices","authors":"Behcet Varışlı, Canan Akman, S. Yildirim, Kenan Atac, O. Çakır","doi":"10.56766/ntms.1068492","DOIUrl":"https://doi.org/10.56766/ntms.1068492","url":null,"abstract":"Introduction: \u0000Drug intoxications may be associated with accidental or suicidal ingestion of toxic agents. In both cases, emergency treatment includes administration of the relevant antidote and gastric decontamination. If necessary, patients are followed up in wards and intensive care units, whereas a group of patients are discharged directly from the emergency department. \u0000Materials and Methods: \u0000The aim of this study was to conduct a retrospective evaluation of examination findings, laboratory investigations, duration of treatments, psychiatric follow-up studies, hospitalization rates and mortality rates in patients admitted to our emergency department due to drug intoxication between 2017 and 2018. \u0000Results: \u0000Of the 126 patients included in our study, 83 were female, with a mean age of 33.58 ± 13.58 years and a range of 18 to 92 years. Of all patients, 76 were hospitalized in the ward and 1 in the intensive care unit, while 49 were treated in the emergency department. One patient had mortality on the eighth day of hospitalization. Eighty-six patients had been on psychiatric treatment prior to admission, whereas 82 patients were referred to the psychiatry department after admission. The rate of psychiatric consultation was significantly higher in patients who were hospitalized in any department due to drug intoxication than in patients who were discharged directly from the emergency department (p","PeriodicalId":371755,"journal":{"name":"New Trends in Medicine Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132743171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Objective: We aimed to show the presence of muscle-joint pain and malaise among the symptoms persisting following Covid-19 disease in regions where brucellosis is endemic. Methods: Fifteen PCR-positive patients diagnosed with Covid-19 after 1 April, 2020, in our hospital and with persisting muscle-joint pain, and testing positive with Brucella agglutination and/or Coombs agglutination 1/160 or above were included in the study. Results: Six (40%) of the patients in the study were male and nine (60%) were female. Males were between the ages of 31-69 and had a median value of 52, while females were between the ages of 38-57 and had a median value of 43. Muscle-joint pain, malaise, fatigue, fever, and sweating were frequently seen symptoms. Time to onset of symptoms in the post-Covid period ranged between seven and 220 days. Conclusion:We think that brucellosis should be considered in the differential diagnosis of patients diagnosed with Covid-19 in endemic regions ad presenting to hospital with symptoms of muscle-joint pain and malaise after treatment.
{"title":"Brucellosis, a rare cause of muscle and joint pain following Covid-19 treatment in endemic regions","authors":"S. Aslan","doi":"10.56766/ntms.1065298","DOIUrl":"https://doi.org/10.56766/ntms.1065298","url":null,"abstract":"ABSTRACT \u0000Objective: We aimed to show the presence of muscle-joint pain and malaise among the symptoms persisting following Covid-19 disease in regions where brucellosis is endemic. \u0000Methods: Fifteen PCR-positive patients diagnosed with Covid-19 after 1 April, 2020, in our hospital and with persisting muscle-joint pain, and testing positive with Brucella agglutination and/or Coombs agglutination 1/160 or above were included in the study. \u0000Results: Six (40%) of the patients in the study were male and nine (60%) were female. Males were between the ages of 31-69 and had a median value of 52, while females were between the ages of 38-57 and had a median value of 43. Muscle-joint pain, malaise, fatigue, fever, and sweating were frequently seen symptoms. Time to onset of symptoms in the post-Covid period ranged between seven and 220 days. \u0000Conclusion:We think that brucellosis should be considered in the differential diagnosis of patients diagnosed with Covid-19 in endemic regions ad presenting to hospital with symptoms of muscle-joint pain and malaise after treatment.","PeriodicalId":371755,"journal":{"name":"New Trends in Medicine Sciences","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126150587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this study, it is aimed to investigate the effect of the pandemic on the professionalism attitudes of medical students. This cross-sectional study was conducted with 329 medical students. The data was collected with sociodemographic information form and Pennsylvania State University Faculty of Medicine Professionalism Attitude Scale. Data were collected via an online survey. SPSS 20 package program was used for statistical analysis. The statistical significance level was p0.05). Students who stated that they preferred medical school because they had an ideal/dream and to help people had significantly higher attitude scores than students who preferred it for other reasons (p
{"title":"The Impact of the COVID-19 Pandemic on Medical Students' Attitudes of Professionalism: A Web Based Cross-Sectional Study","authors":"Esra Çınar Tanrıverdi, E. Gürpınar","doi":"10.56766/ntms.1165669","DOIUrl":"https://doi.org/10.56766/ntms.1165669","url":null,"abstract":"In this study, it is aimed to investigate the effect of the pandemic on the professionalism attitudes of medical students. This cross-sectional study was conducted with 329 medical students. The data was collected with sociodemographic information form and Pennsylvania State University Faculty of Medicine Professionalism Attitude Scale. Data were collected via an online survey. SPSS 20 package program was used for statistical analysis. The statistical significance level was p0.05). Students who stated that they preferred medical school because they had an ideal/dream and to help people had significantly higher attitude scores than students who preferred it for other reasons (p","PeriodicalId":371755,"journal":{"name":"New Trends in Medicine Sciences","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123380260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lung cancer is one of the most common types of cancer worldwide and is responsible for the loss of more than 1 million people each year. It has been reported that the 5-year survival rate of lung cancer is approximately 15% or less due to cell metastasis (World Health Organisation, 2020). Therefore, there is a need to develop adjuvant therapies to prevent death from lung cancer cell metastasis. The aim of our study; The aim of this study is to evaluate the effects of boric acid and bevacizumab on the vascularization, apoptotic, and metastasis steps of A549 lung cancer cells, such as invasion, migration, and epithelial mesenchymal transition(EMT) abilities, either alone or in combination. The study was divided into 4 groups as control(CONT) and boric acid(BA), Boric acid+altuzan(BA+ALT) and altuzan(ALT). The IC50 dose of boric acid was determined by the MTT method. 30μM boric acid and 7 μM Altuzan were applied to BA, BA+ALT and ALT groups for 24 hours. Anti-VEGF for vascularization, Anti-Vimentin for EMT, Anti-MMP-9 for invasion, and Anti-Bax, Anti-Bcl-2 and Anti-Caspase-3 antibodies for apoptosis were stained immunocytochemically and H-Score analysis was performed. . Cell migration was evaluated by the wound healing assay. It was observed that MMP-9 immunoreactivity and apoptotic markers increased in the direction of Cas-3 in the BA group, while the immunoreactivity of Vim and VEGF did not change significantly. When the migration was evaluated, it was observed that the cells did not migrate in the BA and BA+ALT groups at the end of the 24th hour, and the wound areas were closed in the other groups. It was observed that while BA affected the migration, invasion and apoptotic characters of A549 cells independently of bevacizumab, it had no effect on their vascularization properties.
{"title":"IN VITRO EFFECTS OF BORIC ACID AND BEVACIZUMAB IN NON-SMALL CELL LUNG CANCER","authors":"F. Fırat, T. Aladağ","doi":"10.56766/ntms.1147628","DOIUrl":"https://doi.org/10.56766/ntms.1147628","url":null,"abstract":"Lung cancer is one of the most common types of cancer worldwide and is responsible for the loss of more than 1 million people each year. It has been reported that the 5-year survival rate of lung cancer is approximately 15% or less due to cell metastasis (World Health Organisation, 2020). Therefore, there is a need to develop adjuvant therapies to prevent death from lung cancer cell metastasis. The aim of our study; The aim of this study is to evaluate the effects of boric acid and bevacizumab on the vascularization, apoptotic, and metastasis steps of A549 lung cancer cells, such as invasion, migration, and epithelial mesenchymal transition(EMT) abilities, either alone or in combination. \u0000The study was divided into 4 groups as control(CONT) and boric acid(BA), Boric acid+altuzan(BA+ALT) and altuzan(ALT). The IC50 dose of boric acid was determined by the MTT method. 30μM boric acid and 7 μM Altuzan were applied to BA, BA+ALT and ALT groups for 24 hours. Anti-VEGF for vascularization, Anti-Vimentin for EMT, Anti-MMP-9 for invasion, and Anti-Bax, Anti-Bcl-2 and Anti-Caspase-3 antibodies for apoptosis were stained immunocytochemically and H-Score analysis was performed. . Cell migration was evaluated by the wound healing assay. It was observed that MMP-9 immunoreactivity and apoptotic markers increased in the direction of Cas-3 in the BA group, while the immunoreactivity of Vim and VEGF did not change significantly. When the migration was evaluated, it was observed that the cells did not migrate in the BA and BA+ALT groups at the end of the 24th hour, and the wound areas were closed in the other groups. \u0000It was observed that while BA affected the migration, invasion and apoptotic characters of A549 cells independently of bevacizumab, it had no effect on their vascularization properties.","PeriodicalId":371755,"journal":{"name":"New Trends in Medicine Sciences","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128127275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of the study is to evaluate the effectiveness of the hearing screening program in school-age children in Turkey, and to discuss alternative methods for children who cannot be screened due to the COVID-19 pandemic. Within the scope of the school-age hearing screening program, children who fail the screening are referred to reference centers. The effectiveness of the screening program was investigated by recording the ear examinations and definitive audiometric examination results of the children who were referred to a tertiery-level center. Evaluations were made of a total of 87 children, comprising 49 boys (56.3%) and 38 girls (43.7%) with a mean age of 6.97 years, and no risk factors for hearing loss. The physical examination results showed that 53 children were normal, 15 had cerumen impaction, 3 otitis externa, 13 otitis media with effusion and 3 acute otitis media. The audiometric examination results were recorded as 72 normal, 13 conductive hearing loss, and 2 sensorineural hearing loss. Thus, the false positive rate of screening audiometry performed at school was 82.7%. School-age hearing screening is an important test to ensure the cognitive and academic development of children. Pure tone audiometry is indispensable in the evaluation of children who fail the test. For the evaluation of children who could not be tested for 1.5 years due to the COVID-19 pandemic, alternative methods such as tele-audiometry may be utilized.
{"title":"The Effectiveness of the School-Age Hearing Screening Program in Turkey and the Effects of the COVID-19 Pandemic","authors":"U. Yildirim","doi":"10.56766/ntms.1055331","DOIUrl":"https://doi.org/10.56766/ntms.1055331","url":null,"abstract":"The aim of the study is to evaluate the effectiveness of the hearing screening program in school-age children in Turkey, and to discuss alternative methods for children who cannot be screened due to the COVID-19 pandemic. Within the scope of the school-age hearing screening program, children who fail the screening are referred to reference centers. The effectiveness of the screening program was investigated by recording the ear examinations and definitive audiometric examination results of the children who were referred to a tertiery-level center. Evaluations were made of a total of 87 children, comprising 49 boys (56.3%) and 38 girls (43.7%) with a mean age of 6.97 years, and no risk factors for hearing loss. The physical examination results showed that 53 children were normal, 15 had cerumen impaction, 3 otitis externa, 13 otitis media with effusion and 3 acute otitis media. The audiometric examination results were recorded as 72 normal, 13 conductive hearing loss, and 2 sensorineural hearing loss. Thus, the false positive rate of screening audiometry performed at school was 82.7%. School-age hearing screening is an important test to ensure the cognitive and academic development of children. Pure tone audiometry is indispensable in the evaluation of children who fail the test. For the evaluation of children who could not be tested for 1.5 years due to the COVID-19 pandemic, alternative methods such as tele-audiometry may be utilized.","PeriodicalId":371755,"journal":{"name":"New Trends in Medicine Sciences","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127931342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This retrospective study was conducted in order to demonstrate the clinical benefit of infraorbital regional anesthesia performed with intraoperative bupivacaine injection in postoperative pain scores during open septorhinoplasty operations. Postoperative 12-hour pain scores (Visual Analogue Scales) and data obtained from patient files of analgesic consumption of 60 (33 female; 27 male) participants aged 18-45 years who underwent open septorhinoplasty, ASA group I-II, were analyzed.d. The patients were divided into two groups; the control group (group C) included the participant who underwent open septorhinoplasty surgery and did not undergo intraoperative regional anesthesia. Patients who underwent open septorhinoplasty surgery and underwent regional anesthesia with 3 mL (15 mg) of bupivacaine hydrochloride in both infraorbital foramen intraoperatively were included in the bupivacaine group (group B). Patients in group B had lower pain scores at 1 hour postoperatively compared to group C. It was observed that the effective postoperative analgesia continued consistently at the 6th and 12th hours in the patients in group B. At the same time, the need for IV analgesics at the postoperative 12 hours was significantly lower in group B compared to group C. Intraoperative infraorbital regional bupivacaine anesthesia is an effective procedure that reduces postoperative pain levels in septorhinoplasty operations and increases the postoperative comfort of patients.
{"title":"The Effect of Bupivacaine Regional Anesthesia on Postoperative Pain Scores in Open Septorhinoplasty Surgery","authors":"Nihal Efe Atila, I. Ates","doi":"10.56766/ntms.1163500","DOIUrl":"https://doi.org/10.56766/ntms.1163500","url":null,"abstract":"This retrospective study was conducted in order to demonstrate the clinical benefit of infraorbital regional anesthesia performed with intraoperative bupivacaine injection in postoperative pain scores during open septorhinoplasty operations. Postoperative 12-hour pain scores (Visual Analogue Scales) and data obtained from patient files of analgesic consumption of 60 (33 female; 27 male) participants aged 18-45 years who underwent open septorhinoplasty, ASA group I-II, were analyzed.d. The patients were divided into two groups; the control group (group C) included the participant who underwent open septorhinoplasty surgery and did not undergo intraoperative regional anesthesia. Patients who underwent open septorhinoplasty surgery and underwent regional anesthesia with 3 mL (15 mg) of bupivacaine hydrochloride in both infraorbital foramen intraoperatively were included in the bupivacaine group (group B). Patients in group B had lower pain scores at 1 hour postoperatively compared to group C. It was observed that the effective postoperative analgesia continued consistently at the 6th and 12th hours in the patients in group B. At the same time, the need for IV analgesics at the postoperative 12 hours was significantly lower in group B compared to group C. Intraoperative infraorbital regional bupivacaine anesthesia is an effective procedure that reduces postoperative pain levels in septorhinoplasty operations and increases the postoperative comfort of patients.","PeriodicalId":371755,"journal":{"name":"New Trends in Medicine Sciences","volume":"131 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121527297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The COVID-19 pandemic has accelerated the need for long-lasting sanitation solutions in households, businesses, and schools. Current disinfectants, like Lysol, kill bacteria and other microbes only at initial application and are ineffective under aqueous conditions. Copper (II) ions and Lactic Acid are highly regarded for their synergetic, long-lasting antibacterial properties. Although L-pyroglutamic acid holds similar properties, little research has examined its efficacy with copper metal. The purpose of this experiment is to find a novel, clinically safe, antibacterial solution for instantaneous microbial inhibition and continued inhibition over extended periods of time in aqueous solutions. Two antibacterial solutions utilizing Copper (II) Sulfate (10 ppm) were developed with 1% Lactic Acid (Solution A) and 1% L-Pyroglutamic Acid (Solution B). The extinction rate of Escherichia coli K12 bacteria for each solution and Lysol was recorded. The concentration of E. coli was observed via spectrophotometry at 3-time intervals: Initial Introduction (28 Minutes), Short Term (2 Hours) and Long Term (72 hours). At initial introduction, there was no significant difference between solutions (p>0.05) ranging from 22 to 28% E. coli loss from the original sample. Significant growth inhibition (p
2019冠状病毒病大流行加速了对家庭、企业和学校持久卫生解决方案的需求。目前的消毒剂,如来苏,只能在初次使用时杀死细菌和其他微生物,在水条件下无效。铜离子和乳酸因其协同、持久的抗菌性能而受到高度重视。虽然l -焦谷氨酸具有类似的性质,但很少有研究检查其与铜金属的功效。本实验的目的是寻找一种新型的,临床安全的抗菌溶液,用于瞬时微生物抑制和在水溶液中长时间持续抑制。以硫酸铜(II) (10 ppm)为抑菌剂,用1%乳酸(溶液A)和1% l -焦谷氨酸(溶液B)配制两种抑菌液,记录每种溶液和来苏对大肠杆菌K12的杀灭率。采用分光光度法对大肠杆菌浓度进行3个时间间隔的观察:初始引入(28分钟)、短期(2小时)和长期(72小时)。在初始引入时,不同溶液的大肠杆菌损失率(p>0.05)在22% ~ 28%之间,与原始样品相比差异不显著(p>0.05)。显著的生长抑制(p
{"title":"A Novel Long-lasting Aqueous Antibacterial Methodology using L-Pyroglutamic Acid and Copper","authors":"Atiksh Chandra, Sahana Thayagabalu","doi":"10.56766/ntms.1144829","DOIUrl":"https://doi.org/10.56766/ntms.1144829","url":null,"abstract":"The COVID-19 pandemic has accelerated the need for long-lasting sanitation solutions in households, businesses, and schools. Current disinfectants, like Lysol, kill bacteria and other microbes only at initial application and are ineffective under aqueous conditions. Copper (II) ions and Lactic Acid are highly regarded for their synergetic, long-lasting antibacterial properties. Although L-pyroglutamic acid holds similar properties, little research has examined its efficacy with copper metal. The purpose of this experiment is to find a novel, clinically safe, antibacterial solution for instantaneous microbial inhibition and continued inhibition over extended periods of time in aqueous solutions. Two antibacterial solutions utilizing Copper (II) Sulfate (10 ppm) were developed with 1% Lactic Acid (Solution A) and 1% L-Pyroglutamic Acid (Solution B). The extinction rate of Escherichia coli K12 bacteria for each solution and Lysol was recorded. The concentration of E. coli was observed via spectrophotometry at 3-time intervals: Initial Introduction (28 Minutes), Short Term (2 Hours) and Long Term (72 hours). At initial introduction, there was no significant difference between solutions (p>0.05) ranging from 22 to 28% E. coli loss from the original sample. Significant growth inhibition (p","PeriodicalId":371755,"journal":{"name":"New Trends in Medicine Sciences","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122779234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gökhan Sertçakacılar, G. Yıldız, İpek Bostancı, Z. Çukurova
Video-assisted thoracoscopic surgery (VATS) is a minimally invasive procedure with lower pain scores and less morbidity than thoracotomy. However, it is necessary to provide adequate pain control in VATS. For this purpose, blocking visceral and somatic nerve fibers results in successful pain management. This retrospective study evaluated the effect of using different numbers of ports on the success of erector spinae plane block (ESPB) for postoperative analgesia management in patients undergoing VATS. We conducted a retrospective, single-center study between Sep 2020 and Aug 2021. According to the number of ports used, fifty-eight patients were assigned to three groups (single port, dual port, and three-port). Preoperative ultrasound-guided ESPB was performed on all patients. The primary outcome was the numerical rating scale (NRS) score assessed for pain severity at different periods after surgery. The secondary outcome was the postoperative cumulative opioid consumption, and the exploratory outcomes were to determine the length of hospital stay and the incidence of opioid-related side effects. Static and dynamic NRS scores were significantly higher in the three-port group in the first 12-hour postoperative period after admission to the post-anesthesia care unit (p
{"title":"The Effect of the Port Numbers Used in Video-assisted Thoracoscopic Surgery on the Success of Ultrasound-guided Erector Spinae Plane Block; A Single Center Retrospective Study","authors":"Gökhan Sertçakacılar, G. Yıldız, İpek Bostancı, Z. Çukurova","doi":"10.56766/ntms.1143709","DOIUrl":"https://doi.org/10.56766/ntms.1143709","url":null,"abstract":"Video-assisted thoracoscopic surgery (VATS) is a minimally invasive procedure with lower pain scores and less morbidity than thoracotomy. However, it is necessary to provide adequate pain control in VATS. For this purpose, blocking visceral and somatic nerve fibers results in successful pain management. This retrospective study evaluated the effect of using different numbers of ports on the success of erector spinae plane block (ESPB) for postoperative analgesia management in patients undergoing VATS. We conducted a retrospective, single-center study between Sep 2020 and Aug 2021. According to the number of ports used, fifty-eight patients were assigned to three groups (single port, dual port, and three-port). Preoperative ultrasound-guided ESPB was performed on all patients. The primary outcome was the numerical rating scale (NRS) score assessed for pain severity at different periods after surgery. The secondary outcome was the postoperative cumulative opioid consumption, and the exploratory outcomes were to determine the length of hospital stay and the incidence of opioid-related side effects. Static and dynamic NRS scores were significantly higher in the three-port group in the first 12-hour postoperative period after admission to the post-anesthesia care unit (p","PeriodicalId":371755,"journal":{"name":"New Trends in Medicine Sciences","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132771875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}