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Determination of antibacterial activity of St. John's Wort (Hypericum perforatum L.) oil, Nigella sativa oil, Clove (Eugenia caryophyllata) oil, Orange Peel (Citrus sinensis) and Garlic (Allium sativa) oil against microorganisms isolated from clinical samples 测定圣约翰草(贯叶连翘)油、黑草油、丁香(Eugenia caryophyllata)油、柑桔皮(Citrus sinensis)和大蒜(Allium sativa)油对临床分离微生物的抑菌活性
Pub Date : 2022-12-26 DOI: 10.56766/ntms.1177132
Ö. Çelebi, S. Başer, M. Güler, Demet Çelebi, Selahattin Çelebi̇
Objective: The aim of this study is to detect St. John's Wort, Nigella sativa, Clove, Orange Peel and Garlic oil on bacteria isolated from blood culture to determine its antibacterial effect. Methods: One hundered blood samples sent to … Medical Microbiology Laboratory between 1 June 2021 and 1 January 2022 were analyzed with blood culture system. Bacteria isolated from blood culture were passaged into blood agar. Bacterial suspension was prepared from the bacterial colonies at 0.5 Mc Farland turbidity. In order to determine the antibacterial activity of plant extract oils, Minimum Inhibition Concentration and Minimal Bactericidal Concentration values were determined by liquid microdilution method. Also, the zone diameters of the disc diffusion method were measured. Results: The antibacterial effect of plant extract oils was detected on only 10 of the 100 clinical samples included in the study. St. John's Wort oil used in these 10 samples showed the most effective antibacterial effect of 7.81 µg/mL against Staphylococcus haemolyticus and Enterobacter aerogenes. Garlic oil showed the most effective antibacterial effect against Escherichia coli and Staphylococcus haemolyticus at 7.81 µg/mL. Nigella sativa oil showed the most effective antibacterial effect against Staphylococcus haemolyticus at 3.9 µg/mL. Orange Peel oil showed the most effective antibacterial effect against Enterococcus faecalis at 1.95 µg/mL. The minimum inhibition concentration at which the oils were effective on microorganisms was determined by comparing them with standard control strains. Conclusion: More clinical isolates and high-dose studies are needed to determine the effectiveness of plant extract oils. Garlic oil Escherichia coli, Staphylococcus haemolyticus and Enterobacter aerogenes, St. John's wort oil Staphylococcus haemolyticus and Enterobacter aerogenes, Nigella sativa) oil on Staphylococcus haemolyticus has been found to be effective
目的:检测圣约翰草、黑草、丁香、橙皮和大蒜油对血培养分离细菌的抑菌作用,确定其抑菌效果。方法:对2021年6月1日至2022年1月1日送往…医学微生物实验室的100份血样进行血培养系统分析。从血培养中分离的细菌传代到血琼脂中。以0.5 mcfarland浊度的菌落为原料制备菌悬液。为了确定植物提取物的抑菌活性,采用液体微量稀释法测定了最小抑菌浓度和最小杀菌浓度。同时,对圆盘扩散法的区域直径进行了测量。结果:在纳入研究的100份临床样品中,仅有10份检测到植物提取物精油的抗菌作用。10份样品中使用的圣约翰草精油对溶血葡萄球菌和产氧肠杆菌的抑菌效果为7.81µg/mL。大蒜油对大肠杆菌和溶血葡萄球菌的抑菌效果为7.81µg/mL。黑皮油对溶血葡萄球菌的抑菌效果最好,浓度为3.9µg/mL。橙皮油对粪肠球菌的抑菌效果最好,浓度为1.95µg/mL。通过与标准对照菌株的比较,确定了精油对微生物有效抑制的最低浓度。结论:需要更多的临床分离和大剂量研究来确定植物提取物的有效性。已发现大蒜油对大肠杆菌、溶血葡萄球菌和产气肠杆菌、圣约翰草油、溶血葡萄球菌和产气肠杆菌、黑鬼油对溶血葡萄球菌有效
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引用次数: 0
INVESTIGATION OF THE EFFECTIVENESS OF THE ADA PREDIABETES RISK TEST IN IDENTIFYING PREDIABETIC TURKISH PATIENTS AND DETERMINATION OF THE FREQUENCY OF RETINOPATHY IN PREDIABETIC PATIENTS Ada糖尿病前期风险试验在识别土耳其糖尿病前期患者和确定糖尿病前期患者视网膜病变频率方面的有效性研究
Pub Date : 2022-12-01 DOI: 10.56766/ntms.1161735
Ahmet Veli Sanibas, F. Çakmak, I. Baydar, D. Binici
Aim: In this study, the Turkish version of the American Diabetes Association (ADA) prediabetes risk test and the 75-g oral glucose tolerance test (OGTT) were administered to patients to determine the rate of prediabetic patients in our geographical region and investigate its consistency with the ADA risk test. In addition, the presence of retinopathy in prediabetic patients was examined. Material and Method: The study included a total of 342 patients with a fasting plasma glucose value of 100-125 mg/dl. The 75-g OGTT test was performed on the patients. The ADA prediabetes risk test was also administered, and the scores were noted. The OGTT and risk test results were compared. According to the ADA prediabetes risk test, the patients were classified into those at risk for type 2 diabetes mellitus (DM) and those diagnosed with prediabetes. In the evaluation of retinopathy, visual acuity, intraocular pressure measurement, and anterior segment and fundus examinations were performed in each patient. The data of the patients were compared with statistical analysis methods. Results: When the OGTT results of the patients with negative ADA prediabetes risk test scores were compared, the sensitivity was determined as 54% and the specificity as 63% (p0.05). There was no retinopathy finding in the eye examination of 262 of the 342 patients included in the study (p>0.05). Conclusion: In this study, we found that a positive ADA prediabetes risk score was effective in predicting prediabetes, but it was not sufficient. However, prediabetes diagnosed according to OGTT was found to be higher in the patients with negative test scores. Therefore, the prediabetes risk test was not effective in predicting prediabetes among the patients with negative scores.
目的:本研究采用土耳其版美国糖尿病协会(ADA)前驱糖尿病危险试验和75 g口服葡萄糖耐量试验(OGTT)对患者进行检测,以确定我国地理区域内糖尿病前驱患者的发生率,并探讨其与ADA危险试验的一致性。此外,还检查了糖尿病前期患者是否存在视网膜病变。材料与方法:本研究共纳入342例空腹血糖值为100-125 mg/dl的患者。对患者进行75 g OGTT试验。同时进行ADA前驱糖尿病风险测试,并记录得分。比较OGTT和风险测试结果。根据ADA前驱糖尿病危险试验,将患者分为2型糖尿病(DM)危险组和诊断为前驱糖尿病的患者。在评估视网膜病变时,对每位患者进行了视力、眼压测量、前段和眼底检查。采用统计学分析方法对患者资料进行比较。结果:比较ADA前驱糖尿病危险测试评分阴性患者OGTT结果,确定敏感性为54%,特异性为63% (p0.05)。342例患者中有262例眼科检查未发现视网膜病变(p>0.05)。结论:在本研究中,我们发现ADA前驱糖尿病风险评分阳性对预测前驱糖尿病是有效的,但并不充分。然而,根据OGTT诊断的前驱糖尿病在测试分数为阴性的患者中被发现更高。因此,前驱糖尿病风险测试在得分为负的患者中不能有效预测前驱糖尿病。
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引用次数: 0
Evaluation of Patients Admitted To The Emergency Service Due To Poisoning İn Terms of Antidote Use and Decontamination Practices 急诊中毒病人的评价İn解毒剂使用条件和去污做法
Pub Date : 2022-11-11 DOI: 10.56766/ntms.1068492
Behcet Varışlı, Canan Akman, S. Yildirim, Kenan Atac, O. Çakır
Introduction: Drug intoxications may be associated with accidental or suicidal ingestion of toxic agents. In both cases, emergency treatment includes administration of the relevant antidote and gastric decontamination. If necessary, patients are followed up in wards and intensive care units, whereas a group of patients are discharged directly from the emergency department. Materials and Methods: The aim of this study was to conduct a retrospective evaluation of examination findings, laboratory investigations, duration of treatments, psychiatric follow-up studies, hospitalization rates and mortality rates in patients admitted to our emergency department due to drug intoxication between 2017 and 2018. Results: Of the 126 patients included in our study, 83 were female, with a mean age of 33.58 ± 13.58 years and a range of 18 to 92 years. Of all patients, 76 were hospitalized in the ward and 1 in the intensive care unit, while 49 were treated in the emergency department. One patient had mortality on the eighth day of hospitalization. Eighty-six patients had been on psychiatric treatment prior to admission, whereas 82 patients were referred to the psychiatry department after admission. The rate of psychiatric consultation was significantly higher in patients who were hospitalized in any department due to drug intoxication than in patients who were discharged directly from the emergency department (p
药物中毒可能与意外或自杀性摄入有毒物质有关。在这两种情况下,紧急治疗包括给予相关的解毒剂和胃净化。如有必要,患者在病房和重症监护病房随访,而一组患者直接从急诊科出院。材料与方法:本研究的目的是回顾性评价2017年至2018年在我急诊科就诊的药物中毒患者的检查结果、实验室调查、治疗时间、精神病学随访研究、住院率和死亡率。结果:126例患者中,女性83例,平均年龄(33.58±13.58)岁,年龄范围18 ~ 92岁。在所有患者中,76人在病房住院,1人在重症监护病房住院,49人在急诊科接受治疗。1例患者在住院第8天死亡。86名患者在入院前接受过精神科治疗,而82名患者在入院后被转介到精神科。由于药物中毒而在任何科室住院的患者的精神科会诊率明显高于直接从急诊科出院的患者(p
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引用次数: 0
Brucellosis, a rare cause of muscle and joint pain following Covid-19 treatment in endemic regions 布鲁氏菌病,在流行地区治疗Covid-19后引起肌肉和关节疼痛的罕见原因
Pub Date : 2022-09-22 DOI: 10.56766/ntms.1065298
S. Aslan
ABSTRACT Objective: We aimed to show the presence of muscle-joint pain and malaise among the symptoms persisting following Covid-19 disease in regions where brucellosis is endemic. Methods: Fifteen PCR-positive patients diagnosed with Covid-19 after 1 April, 2020, in our hospital and with persisting muscle-joint pain, and testing positive with Brucella agglutination and/or Coombs agglutination 1/160 or above were included in the study. Results: Six (40%) of the patients in the study were male and nine (60%) were female. Males were between the ages of 31-69 and had a median value of 52, while females were between the ages of 38-57 and had a median value of 43. Muscle-joint pain, malaise, fatigue, fever, and sweating were frequently seen symptoms. Time to onset of symptoms in the post-Covid period ranged between seven and 220 days. Conclusion:We think that brucellosis should be considered in the differential diagnosis of patients diagnosed with Covid-19 in endemic regions ad presenting to hospital with symptoms of muscle-joint pain and malaise after treatment.
摘要目的:我们旨在了解布鲁氏菌病流行地区2019冠状病毒病(Covid-19)后持续出现的症状中是否存在肌肉-关节疼痛和不适。方法:选取2020年4月1日后在我院诊断为Covid-19且持续存在肌肉关节疼痛的pcr阳性患者15例,布鲁氏菌凝集和/或库姆斯凝集1/160及以上检测阳性。结果:男性6例(40%),女性9例(60%)。男性年龄在31-69岁之间,中位数为52,而女性年龄在38-57岁之间,中位数为43。肌肉关节疼痛、不适、疲劳、发热和出汗是常见的症状。在新冠病毒感染后的7至220天期间,出现症状的时间不等。结论:我们认为在流行地区诊断为Covid-19的患者,治疗后以肌肉关节疼痛和不适症状就诊的患者应考虑布鲁氏菌病的鉴别诊断。
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引用次数: 0
The Impact of the COVID-19 Pandemic on Medical Students' Attitudes of Professionalism: A Web Based Cross-Sectional Study 新冠肺炎疫情对医学生专业态度的影响:基于网络的横断面研究
Pub Date : 2022-09-14 DOI: 10.56766/ntms.1165669
Esra Çınar Tanrıverdi, E. Gürpınar
In this study, it is aimed to investigate the effect of the pandemic on the professionalism attitudes of medical students. This cross-sectional study was conducted with 329 medical students. The data was collected with sociodemographic information form and Pennsylvania State University Faculty of Medicine Professionalism Attitude Scale. Data were collected via an online survey. SPSS 20 package program was used for statistical analysis. The statistical significance level was p0.05). Students who stated that they preferred medical school because they had an ideal/dream and to help people had significantly higher attitude scores than students who preferred it for other reasons (p
本研究旨在探讨疫情对医学生专业态度的影响。本横断面研究以329名医学生为研究对象。数据采用社会人口统计信息表和宾夕法尼亚州立大学医学院专业态度量表收集。数据是通过在线调查收集的。采用SPSS 20软件包程序进行统计分析。p < 0.05)。那些说他们喜欢医学院是因为他们有理想/梦想和帮助别人的学生的态度得分明显高于那些因为其他原因而喜欢医学院的学生(p
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引用次数: 1
IN VITRO EFFECTS OF BORIC ACID AND BEVACIZUMAB IN NON-SMALL CELL LUNG CANCER 硼酸和贝伐单抗治疗非小细胞肺癌的体外效果
Pub Date : 2022-09-14 DOI: 10.56766/ntms.1147628
F. Fırat, T. Aladağ
Lung cancer is one of the most common types of cancer worldwide and is responsible for the loss of more than 1 million people each year. It has been reported that the 5-year survival rate of lung cancer is approximately 15% or less due to cell metastasis (World Health Organisation, 2020). Therefore, there is a need to develop adjuvant therapies to prevent death from lung cancer cell metastasis. The aim of our study; The aim of this study is to evaluate the effects of boric acid and bevacizumab on the vascularization, apoptotic, and metastasis steps of A549 lung cancer cells, such as invasion, migration, and epithelial mesenchymal transition(EMT) abilities, either alone or in combination. The study was divided into 4 groups as control(CONT) and boric acid(BA), Boric acid+altuzan(BA+ALT) and altuzan(ALT). The IC50 dose of boric acid was determined by the MTT method. 30μM boric acid and 7 μM Altuzan were applied to BA, BA+ALT and ALT groups for 24 hours. Anti-VEGF for vascularization, Anti-Vimentin for EMT, Anti-MMP-9 for invasion, and Anti-Bax, Anti-Bcl-2 and Anti-Caspase-3 antibodies for apoptosis were stained immunocytochemically and H-Score analysis was performed. . Cell migration was evaluated by the wound healing assay. It was observed that MMP-9 immunoreactivity and apoptotic markers increased in the direction of Cas-3 in the BA group, while the immunoreactivity of Vim and VEGF did not change significantly. When the migration was evaluated, it was observed that the cells did not migrate in the BA and BA+ALT groups at the end of the 24th hour, and the wound areas were closed in the other groups. It was observed that while BA affected the migration, invasion and apoptotic characters of A549 cells independently of bevacizumab, it had no effect on their vascularization properties.
肺癌是世界上最常见的癌症类型之一,每年导致100多万人死亡。据报道,由于细胞转移,肺癌的5年生存率约为15%或更低(世界卫生组织,2020)。因此,有必要开发辅助治疗,以防止肺癌细胞转移死亡。我们研究的目的;本研究的目的是评估硼酸和贝伐单抗单独或联合使用对A549肺癌细胞血管化、凋亡和转移的影响,如侵袭、迁移和上皮间充质转化(EMT)能力。研究分为4组,分别为对照组(CONT)和硼酸组(BA)、硼酸+altuzan(BA+ALT)和altuzan(ALT)。采用MTT法测定硼酸的IC50剂量。BA组、BA+ALT组和ALT组分别应用30μM硼酸和7 μM Altuzan治疗24小时。免疫细胞化学染色抗bax、抗bcl -2和抗caspase -3抗体,并进行H-Score分析。通过伤口愈合试验评估细胞迁移。我们观察到BA组MMP-9免疫反应性和凋亡标志物沿Cas-3方向升高,而Vim和VEGF免疫反应性无明显变化。观察迁移情况,24小时末,BA组和BA+ALT组细胞无迁移,其余组创面闭合。我们观察到BA虽然独立于贝伐单抗影响A549细胞的迁移、侵袭和凋亡特性,但对其血管化特性没有影响。
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引用次数: 0
The Effectiveness of the School-Age Hearing Screening Program in Turkey and the Effects of the COVID-19 Pandemic 土耳其学龄听力筛查项目的有效性和COVID-19大流行的影响
Pub Date : 2022-09-14 DOI: 10.56766/ntms.1055331
U. Yildirim
The aim of the study is to evaluate the effectiveness of the hearing screening program in school-age children in Turkey, and to discuss alternative methods for children who cannot be screened due to the COVID-19 pandemic. Within the scope of the school-age hearing screening program, children who fail the screening are referred to reference centers. The effectiveness of the screening program was investigated by recording the ear examinations and definitive audiometric examination results of the children who were referred to a tertiery-level center. Evaluations were made of a total of 87 children, comprising 49 boys (56.3%) and 38 girls (43.7%) with a mean age of 6.97 years, and no risk factors for hearing loss. The physical examination results showed that 53 children were normal, 15 had cerumen impaction, 3 otitis externa, 13 otitis media with effusion and 3 acute otitis media. The audiometric examination results were recorded as 72 normal, 13 conductive hearing loss, and 2 sensorineural hearing loss. Thus, the false positive rate of screening audiometry performed at school was 82.7%. School-age hearing screening is an important test to ensure the cognitive and academic development of children. Pure tone audiometry is indispensable in the evaluation of children who fail the test. For the evaluation of children who could not be tested for 1.5 years due to the COVID-19 pandemic, alternative methods such as tele-audiometry may be utilized.
该研究的目的是评估土耳其学龄儿童听力筛查计划的有效性,并讨论因COVID-19大流行而无法接受筛查的儿童的替代方法。在学龄听力筛查计划的范围内,未通过筛查的儿童被转介到参考中心。通过记录转介到三级中心的儿童的耳部检查和最终听力学检查结果来调查筛查方案的有效性。共对87例儿童进行评估,其中男孩49例(56.3%),女孩38例(43.7%),平均年龄6.97岁,无听力损失危险因素。体检结果:正常53例,耵聍嵌塞15例,外耳炎3例,中耳炎伴积液13例,急性中耳炎3例。听力检查结果为正常72例,传导性听力损失13例,感音神经性听力损失2例。因此,在学校进行的听力筛查假阳性率为82.7%。学龄期听力筛查是保证儿童认知和学业发展的重要测试。纯音听力学在对考试不及格儿童的评价中是不可缺少的。对于因COVID-19大流行而无法检测1.5年的儿童的评估,可采用远程测听等替代方法。
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引用次数: 0
The Effect of Bupivacaine Regional Anesthesia on Postoperative Pain Scores in Open Septorhinoplasty Surgery 布比卡因区域麻醉对开放式鼻中隔成形术术后疼痛评分的影响
Pub Date : 2022-09-14 DOI: 10.56766/ntms.1163500
Nihal Efe Atila, I. Ates
This retrospective study was conducted in order to demonstrate the clinical benefit of infraorbital regional anesthesia performed with intraoperative bupivacaine injection in postoperative pain scores during open septorhinoplasty operations. Postoperative 12-hour pain scores (Visual Analogue Scales) and data obtained from patient files of analgesic consumption of 60 (33 female; 27 male) participants aged 18-45 years who underwent open septorhinoplasty, ASA group I-II, were analyzed.d. The patients were divided into two groups; the control group (group C) included the participant who underwent open septorhinoplasty surgery and did not undergo intraoperative regional anesthesia. Patients who underwent open septorhinoplasty surgery and underwent regional anesthesia with 3 mL (15 mg) of bupivacaine hydrochloride in both infraorbital foramen intraoperatively were included in the bupivacaine group (group B). Patients in group B had lower pain scores at 1 hour postoperatively compared to group C. It was observed that the effective postoperative analgesia continued consistently at the 6th and 12th hours in the patients in group B. At the same time, the need for IV analgesics at the postoperative 12 hours was significantly lower in group B compared to group C. Intraoperative infraorbital regional bupivacaine anesthesia is an effective procedure that reduces postoperative pain levels in septorhinoplasty operations and increases the postoperative comfort of patients.
本回顾性研究旨在证明术中布比卡因眶下区域麻醉对开放性鼻中隔成形术术后疼痛评分的临床益处。术后12小时疼痛评分(视觉模拟量表)和数据来自60例(女性33例;27名年龄在18-45岁的男性接受了开放式鼻中隔成形术,ASA组I-II。患者分为两组;对照组(C组)包括接受开放式鼻中隔成形术且未进行术中区域麻醉的参与者。行切开鼻中隔成形术,术中双眶下孔区域麻醉3ml (15mg)盐酸布比卡因的患者被纳入布比卡因组(B组)。B组患者术后1小时疼痛评分较c组低,观察到B组患者术后6、12小时有效镇痛持续一致。术中眶下区域布比卡因麻醉是一种有效的方法,可减少鼻中隔成形术术后疼痛水平,提高患者术后舒适度。
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引用次数: 1
A Novel Long-lasting Aqueous Antibacterial Methodology using L-Pyroglutamic Acid and Copper l -焦谷氨酸和铜的新型长效水性抗菌方法
Pub Date : 2022-08-24 DOI: 10.56766/ntms.1144829
Atiksh Chandra, Sahana Thayagabalu
The COVID-19 pandemic has accelerated the need for long-lasting sanitation solutions in households, businesses, and schools. Current disinfectants, like Lysol, kill bacteria and other microbes only at initial application and are ineffective under aqueous conditions. Copper (II) ions and Lactic Acid are highly regarded for their synergetic, long-lasting antibacterial properties. Although L-pyroglutamic acid holds similar properties, little research has examined its efficacy with copper metal. The purpose of this experiment is to find a novel, clinically safe, antibacterial solution for instantaneous microbial inhibition and continued inhibition over extended periods of time in aqueous solutions. Two antibacterial solutions utilizing Copper (II) Sulfate (10 ppm) were developed with 1% Lactic Acid (Solution A) and 1% L-Pyroglutamic Acid (Solution B). The extinction rate of Escherichia coli K12 bacteria for each solution and Lysol was recorded. The concentration of E. coli was observed via spectrophotometry at 3-time intervals: Initial Introduction (28 Minutes), Short Term (2 Hours) and Long Term (72 hours). At initial introduction, there was no significant difference between solutions (p>0.05) ranging from 22 to 28% E. coli loss from the original sample. Significant growth inhibition (p
2019冠状病毒病大流行加速了对家庭、企业和学校持久卫生解决方案的需求。目前的消毒剂,如来苏,只能在初次使用时杀死细菌和其他微生物,在水条件下无效。铜离子和乳酸因其协同、持久的抗菌性能而受到高度重视。虽然l -焦谷氨酸具有类似的性质,但很少有研究检查其与铜金属的功效。本实验的目的是寻找一种新型的,临床安全的抗菌溶液,用于瞬时微生物抑制和在水溶液中长时间持续抑制。以硫酸铜(II) (10 ppm)为抑菌剂,用1%乳酸(溶液A)和1% l -焦谷氨酸(溶液B)配制两种抑菌液,记录每种溶液和来苏对大肠杆菌K12的杀灭率。采用分光光度法对大肠杆菌浓度进行3个时间间隔的观察:初始引入(28分钟)、短期(2小时)和长期(72小时)。在初始引入时,不同溶液的大肠杆菌损失率(p>0.05)在22% ~ 28%之间,与原始样品相比差异不显著(p>0.05)。显著的生长抑制(p
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引用次数: 0
The Effect of the Port Numbers Used in Video-assisted Thoracoscopic Surgery on the Success of Ultrasound-guided Erector Spinae Plane Block; A Single Center Retrospective Study 视频胸腔镜手术中端口号对超声引导直立者脊柱平面阻滞成功的影响单中心回顾性研究
Pub Date : 2022-08-08 DOI: 10.56766/ntms.1143709
Gökhan Sertçakacılar, G. Yıldız, İpek Bostancı, Z. Çukurova
Video-assisted thoracoscopic surgery (VATS) is a minimally invasive procedure with lower pain scores and less morbidity than thoracotomy. However, it is necessary to provide adequate pain control in VATS. For this purpose, blocking visceral and somatic nerve fibers results in successful pain management. This retrospective study evaluated the effect of using different numbers of ports on the success of erector spinae plane block (ESPB) for postoperative analgesia management in patients undergoing VATS. We conducted a retrospective, single-center study between Sep 2020 and Aug 2021. According to the number of ports used, fifty-eight patients were assigned to three groups (single port, dual port, and three-port). Preoperative ultrasound-guided ESPB was performed on all patients. The primary outcome was the numerical rating scale (NRS) score assessed for pain severity at different periods after surgery. The secondary outcome was the postoperative cumulative opioid consumption, and the exploratory outcomes were to determine the length of hospital stay and the incidence of opioid-related side effects. Static and dynamic NRS scores were significantly higher in the three-port group in the first 12-hour postoperative period after admission to the post-anesthesia care unit (p
视频胸腔镜手术(VATS)是一种微创手术,疼痛评分较低,发病率低于开胸手术。然而,在VATS中提供足够的疼痛控制是必要的。为此,阻断内脏和躯体神经纤维可以成功地控制疼痛。本回顾性研究评估了不同端口数量对VATS患者使用竖脊平面阻滞(ESPB)术后镇痛管理成功的影响。我们在2020年9月至2021年8月期间进行了一项回顾性单中心研究。根据使用的端口数量,将58例患者分为三组(单端口、双端口和三端口)。所有患者术前均行超声引导下ESPB。主要终点是术后不同时期疼痛严重程度的数值评定量表(NRS)评分。次要结局是术后阿片类药物的累积消耗,探索性结局是确定住院时间和阿片类药物相关副作用的发生率。三端口组的静态和动态NRS评分在麻醉后护理单元入院后的第一个12小时内明显更高(p
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引用次数: 0
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