This research aimed to investigate the effectiveness of using educational robots in extra-curricular projects to enhance creative thinking skills among students. To achieve this aim, a semi-experimental approach was followed, which involved training students to design and program an educational robot and use different cognitive skills derived from all their academic courses to solve a problem. The research sample consisted of (16) students in the fifth grade of Smart Learning Primary School. They were randomly divided into two equal groups: a control group and an experimental group. The Torrance Test of Creative Thinking, form (B), was used as a tool for this research to determine any improvement in the students' creative thinking skills. The results showed statistically significant differences between the experimental and the control groups when their creative thinking skills – fluency, flexibility, and originality – were tested after they had used educational robots in extra-curricular projects, even taking into account several factors that could have increased their skills in these areas. This research recommends expanding the use of educational robotics activities to develop higher-order thinking skills among students. The research also recommends providing teachers with adequate training and technical support to employ robotics technology in education. KEYWORDS Artificial intelligence, 21st-century skills, problem-solving skills, learning activities, educational programming, higher thinking skills, robotics
{"title":"Educational Robots and Creative Thinking Skills","authors":"Renad Alrobia, N. Alsaleh","doi":"10.37575/h/edu/210080","DOIUrl":"https://doi.org/10.37575/h/edu/210080","url":null,"abstract":"This research aimed to investigate the effectiveness of using educational robots in extra-curricular projects to enhance creative thinking skills among students. To achieve this aim, a semi-experimental approach was followed, which involved training students to design and program an educational robot and use different cognitive skills derived from all their academic courses to solve a problem. The research sample consisted of (16) students in the fifth grade of Smart Learning Primary School. They were randomly divided into two equal groups: a control group and an experimental group. The Torrance Test of Creative Thinking, form (B), was used as a tool for this research to determine any improvement in the students' creative thinking skills. The results showed statistically significant differences between the experimental and the control groups when their creative thinking skills – fluency, flexibility, and originality – were tested after they had used educational robots in extra-curricular projects, even taking into account several factors that could have increased their skills in these areas. This research recommends expanding the use of educational robotics activities to develop higher-order thinking skills among students. The research also recommends providing teachers with adequate training and technical support to employ robotics technology in education. KEYWORDS Artificial intelligence, 21st-century skills, problem-solving skills, learning activities, educational programming, higher thinking skills, robotics","PeriodicalId":39024,"journal":{"name":"Scientific Journal of King Faisal University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80729963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Despite the positive effects of physical activity on type 2 diabetes mellitus (T2DM) management, the lack of adequate evidence on the effects of dietary intake has raised concerns. This study aimed to assess dietary intake and its effect on glycaemic control among active and inactive patients with T2DM. A cross-sectional observational study was conducted on patients with T2DM. Dietary food intake and physical activity were assessed using a validated questionnaire through face-to-face interviews. The daily consumption of fruit and vegetables was significantly higher in active patients compared with inactive patients (p = 0.00). Significantly higher daily rice consumption (p = 0.00) and lower dietary non-starch polysaccharide (NSP) intake (p < 0.01) were reported among inactive patients compared with active patients. The results also revealed a significantly higher glycated haemoglobin (HbA1c) level (8.37 1.51% vs 8.015 1.50%; p=0.02) and BMI (34.956.06 kg/m2 vs 31.725.62 kg/m2; p = 0.00) among inactive patients compared with active patients. A positive correlation was found between physical activity and NSP intake. The study found that a variety of lifestyle modifications, including increased physical activity and fruit and vegetable consumption, could help manage glycaemic control in patients. The study further found that carbohydrate-rich NSPs may help lower BMI levels in patients with T2DM. KEYWORDS Dietary intake, glycaemic control, lifestyle, physical activity
尽管体育活动对2型糖尿病(T2DM)的管理有积极作用，但缺乏足够的证据表明饮食摄入的影响引起了人们的关注。本研究旨在评估饮食摄入及其对活跃和不活跃T2DM患者血糖控制的影响。对T2DM患者进行了横断面观察性研究。通过面对面访谈，使用有效的问卷对饮食食物摄入量和身体活动进行评估。运动患者的日常水果和蔬菜摄入量明显高于不运动患者(p = 0.00)。与运动患者相比，不运动患者的日大米摄入量显著增加(p = 0.00)，非淀粉多糖(NSP)摄入量显著降低(p < 0.01)。结果还显示糖化血红蛋白(HbA1c)水平显著升高(8.371.51% vs 8.0151.50%;p=0.02)和BMI(34.956.06 kg/m2 vs 31.725.62 kg/m2;P = 0.00)。体力活动与NSP摄入量呈正相关。研究发现，各种生活方式的改变，包括增加体力活动和水果和蔬菜的摄入，可以帮助患者控制血糖。研究进一步发现，富含碳水化合物的NSPs可能有助于降低2型糖尿病患者的BMI水平。关键词:饮食摄入;血糖控制;生活方式
{"title":"Dietary Intake and Health Status in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study","authors":"M. Al-Mssallem, Sehad Al-Arifi","doi":"10.37575/b/agr/220001","DOIUrl":"https://doi.org/10.37575/b/agr/220001","url":null,"abstract":"Despite the positive effects of physical activity on type 2 diabetes mellitus (T2DM) management, the lack of adequate evidence on the effects of dietary intake has raised concerns. This study aimed to assess dietary intake and its effect on glycaemic control among active and inactive patients with T2DM. A cross-sectional observational study was conducted on patients with T2DM. Dietary food intake and physical activity were assessed using a validated questionnaire through face-to-face interviews. The daily consumption of fruit and vegetables was significantly higher in active patients compared with inactive patients (p = 0.00). Significantly higher daily rice consumption (p = 0.00) and lower dietary non-starch polysaccharide (NSP) intake (p < 0.01) were reported among inactive patients compared with active patients. The results also revealed a significantly higher glycated haemoglobin (HbA1c) level (8.37 1.51% vs 8.015 1.50%; p=0.02) and BMI (34.956.06 kg/m2 vs 31.725.62 kg/m2; p = 0.00) among inactive patients compared with active patients. A positive correlation was found between physical activity and NSP intake. The study found that a variety of lifestyle modifications, including increased physical activity and fruit and vegetable consumption, could help manage glycaemic control in patients. The study further found that carbohydrate-rich NSPs may help lower BMI levels in patients with T2DM. KEYWORDS Dietary intake, glycaemic control, lifestyle, physical activity","PeriodicalId":39024,"journal":{"name":"Scientific Journal of King Faisal University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69891643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global experiences of planning urban areas are characterised by adopting hierarchical structures from large to small structures, i.e. residential quarter (large residential area), residential district and then residential neighbourhood. Each structure is characterised according to the area, the number of people and the services required for targeting a sustainable urban environment. This concept is a milestone in urban planning in Saudi Arabia. The research attempted to discuss the general trend of planning housing projects in Saudi Arabia and the extent of applying the hierarchal concept. Three models were chosen randomly in Makkah, showing such planning hierarchy. These are Al Shawqiyyah, Al Sharaie and Al Rabwah. These projects were planned four decades ago and became a reality. Through comparative analytical methods, findings revealed ambiguity of the hierarchal planning concept in these projects. Further, the traditional neighbourhood concept was prevalent in most neighbourhoods characterised by low-density development in planning but medium and high densities in reality. The problem is getting worse as cities grow horizontally and vertically. Consistent scientific analysis based on practice and continuous meta-analysis was used. The paper calls for the need to change the current premises of housing plans and reorganise the accumulated problems according to global experiences and local standards.
全球城市规划经验的特点是采用由大到小的层次结构，即住宅区(大住宅区)-住宅区-居民区。每个结构都根据区域、人口数量和可持续城市环境所需的服务来特征化。这个概念是沙特阿拉伯城市规划的一个里程碑。本研究试图探讨在沙特阿拉伯规划住房项目的总体趋势和应用层次概念的程度。在麦加随机选择了三个模型，显示了这样的规划层次。他们是Al Shawqiyyah, Al Sharaie和Al Rabwah。这些项目早在40年前就计划好了，并成为了现实。通过比较分析的方法，研究结果揭示了这些项目中层次规划概念的模糊性。此外，传统的社区概念在大多数社区中普遍存在，其特点是规划上的低密度发展，但实际上是中密度和高密度。随着城市的横向和纵向发展，这个问题变得越来越严重。采用基于实践的一致性科学分析和连续元分析。本文呼吁改变现有住房规划的前提，根据国际经验和地方标准对积累的问题进行整理。
{"title":"Planning of Urban Quarters, Districts and Neighbourhoods in Islam’s Holiest City: A Comparative Analytical Study","authors":"Abdo Absi, Adel M. Binyaseen, Abdulghani Monawar","doi":"10.37575/b/eng/210053","DOIUrl":"https://doi.org/10.37575/b/eng/210053","url":null,"abstract":"Global experiences of planning urban areas are characterised by adopting hierarchical structures from large to small structures, i.e. residential quarter (large residential area), residential district and then residential neighbourhood. Each structure is characterised according to the area, the number of people and the services required for targeting a sustainable urban environment. This concept is a milestone in urban planning in Saudi Arabia. The research attempted to discuss the general trend of planning housing projects in Saudi Arabia and the extent of applying the hierarchal concept. Three models were chosen randomly in Makkah, showing such planning hierarchy. These are Al Shawqiyyah, Al Sharaie and Al Rabwah. These projects were planned four decades ago and became a reality. Through comparative analytical methods, findings revealed ambiguity of the hierarchal planning concept in these projects. Further, the traditional neighbourhood concept was prevalent in most neighbourhoods characterised by low-density development in planning but medium and high densities in reality. The problem is getting worse as cities grow horizontally and vertically. Consistent scientific analysis based on practice and continuous meta-analysis was used. The paper calls for the need to change the current premises of housing plans and reorganise the accumulated problems according to global experiences and local standards.","PeriodicalId":39024,"journal":{"name":"Scientific Journal of King Faisal University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69893257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aims to identify the perceptions of faculty members at King Saud University on using virtual platforms during the coronavirus pandemic. It reveals the differences among their opinions both before and during the pandemic as well as the various methods used to determine their views. It furthermore offers explanations for these views. 79 members were sampled during the pandemic and 74 members before it. The perceptions of both samples differed regarding needs, obstacles, procedures, and recommendations related to virtual platforms. The initial needs of the pre-sample focused on ‘training’, whereas the post-sample focused on the necessity of ‘technical support’. Both samples agreed that the obstacles facing the use of virtual platforms fell into three main categories: the importance of technical support, administrative considerations, and training. The two samples suggested focusing on laying down policy for management and decision-makers related to the adoption of ‘teaching strategies’. These should be based on the use of relatively blended learning designed to promote continued future use of virtual platforms. The study recommended considering the necessity of pedagogically employing virtual platforms in universities and raising awareness of eTeaching methods among members. It similarly suggested reducing obstacles and difficulties by means of continuous evaluation and addressing any problems. KEYWORDS Virtual teaching, perceptions, thematic analysis, electronic culture, higher education, eLearning.
{"title":"The Shift in Academics’ Conception of Virtual Platforms due to the Coronavirus Pandemic: The Saudi Context","authors":"Mohammed Alhojailan","doi":"10.37575/h/edu/220019","DOIUrl":"https://doi.org/10.37575/h/edu/220019","url":null,"abstract":"This study aims to identify the perceptions of faculty members at King Saud University on using virtual platforms during the coronavirus pandemic. It reveals the differences among their opinions both before and during the pandemic as well as the various methods used to determine their views. It furthermore offers explanations for these views. 79 members were sampled during the pandemic and 74 members before it. The perceptions of both samples differed regarding needs, obstacles, procedures, and recommendations related to virtual platforms. The initial needs of the pre-sample focused on ‘training’, whereas the post-sample focused on the necessity of ‘technical support’. Both samples agreed that the obstacles facing the use of virtual platforms fell into three main categories: the importance of technical support, administrative considerations, and training. The two samples suggested focusing on laying down policy for management and decision-makers related to the adoption of ‘teaching strategies’. These should be based on the use of relatively blended learning designed to promote continued future use of virtual platforms. The study recommended considering the necessity of pedagogically employing virtual platforms in universities and raising awareness of eTeaching methods among members. It similarly suggested reducing obstacles and difficulties by means of continuous evaluation and addressing any problems. KEYWORDS Virtual teaching, perceptions, thematic analysis, electronic culture, higher education, eLearning.","PeriodicalId":39024,"journal":{"name":"Scientific Journal of King Faisal University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75429621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This research aims to identify the effectiveness of a proposed program based on “Text Grammar” (teaching languages through the linguistic context) in developing analytical and critical reading skills through the language skills course for first-level students in the Bachelor of Arabic Language at the Faculty of Arts, Jouf University. To achieve this goal, two lists of analytical reading skills and critical reading skills were built, and the foundations for building the proposed program were identified. The research was based on the experimental design of one group (30 students). The researcher prepared the analytical and critical reading tests, and they were applied before and after the experiment. The research achieved several results, the most important of which are: (1) the effectiveness of the proposed program in developing analytical reading skills and (2) critical reading skills at all levels of the research group. Recommendations presented include (1) to reconsider teaching Arabic language and literature program courses in the context of text grammar and (2) training faculty members. It is also necessary to include text grammar, its teaching strategies within the description of the Bachelor of Arabic Language and Literature program, and the description of the courses. Finally, a number of text grammar studies for teaching Arabic are suggested. KEYWORDS literary criticism, reading comprehension, Arabic language, literature, language skills, higher education
{"title":"Developing Analytical and Critical Reading Skills Through the Linguistic Context: The Philosophy of Text Grammar","authors":"Mahmoud Abdel Hafez Khalaf Allah","doi":"10.37575/h/edu/220005","DOIUrl":"https://doi.org/10.37575/h/edu/220005","url":null,"abstract":"This research aims to identify the effectiveness of a proposed program based on “Text Grammar” (teaching languages through the linguistic context) in developing analytical and critical reading skills through the language skills course for first-level students in the Bachelor of Arabic Language at the Faculty of Arts, Jouf University. To achieve this goal, two lists of analytical reading skills and critical reading skills were built, and the foundations for building the proposed program were identified. The research was based on the experimental design of one group (30 students). The researcher prepared the analytical and critical reading tests, and they were applied before and after the experiment. The research achieved several results, the most important of which are: (1) the effectiveness of the proposed program in developing analytical reading skills and (2) critical reading skills at all levels of the research group. Recommendations presented include (1) to reconsider teaching Arabic language and literature program courses in the context of text grammar and (2) training faculty members. It is also necessary to include text grammar, its teaching strategies within the description of the Bachelor of Arabic Language and Literature program, and the description of the courses. Finally, a number of text grammar studies for teaching Arabic are suggested. KEYWORDS literary criticism, reading comprehension, Arabic language, literature, language skills, higher education","PeriodicalId":39024,"journal":{"name":"Scientific Journal of King Faisal University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77274027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of this study is to determine the behavioural intentions and actual usage of online learning apps through the lens of the unified theory of acceptance and use of technology, which is a synthesis of numerous theories and models and is most commonly used to examine technology adoption behaviours. The study has utilised an exploratory research design, and data were collected using a questionnaire survey. The items used for establishing the questionnaire to measure the study constructs are adopted from different valid studies conducted previously. The current study examines the role of various factors, including performance expectancy, effort expectancy, social influence, hedonic motivations, price value, and habits on the behavioural intentions of Saudi students using online learning apps. The data were collected from 245 Saudi university students and then analysed using structural equational modelling. The results highlight that an emphasis on all the theory elements, including performance expectancy, effort expectancy, social influence, hedonic motivations, price value, and habits, can positively lead to behavioural intention to use online learning apps, leading in turn to actual usage. Although these results can be put into the context of future studies, the study encourages practitioners, policymakers, and educational designers to focus on performance expectancy, effort expectancy, social influence, habit, price value, and hedonic motivation when designing and adopting online learning apps for Saudi university students. KEYWORDS educational technology, m-learning, higher education, technology acceptance, Saudi Arabia
{"title":"Online Learning Apps Adoption in the Saudi Context: A Perspective on the Unified Theory of Acceptance and Use of Technology","authors":"Ahmad Almufarreh","doi":"10.37575/h/edu/220027","DOIUrl":"https://doi.org/10.37575/h/edu/220027","url":null,"abstract":"The aim of this study is to determine the behavioural intentions and actual usage of online learning apps through the lens of the unified theory of acceptance and use of technology, which is a synthesis of numerous theories and models and is most commonly used to examine technology adoption behaviours. The study has utilised an exploratory research design, and data were collected using a questionnaire survey. The items used for establishing the questionnaire to measure the study constructs are adopted from different valid studies conducted previously. The current study examines the role of various factors, including performance expectancy, effort expectancy, social influence, hedonic motivations, price value, and habits on the behavioural intentions of Saudi students using online learning apps. The data were collected from 245 Saudi university students and then analysed using structural equational modelling. The results highlight that an emphasis on all the theory elements, including performance expectancy, effort expectancy, social influence, hedonic motivations, price value, and habits, can positively lead to behavioural intention to use online learning apps, leading in turn to actual usage. Although these results can be put into the context of future studies, the study encourages practitioners, policymakers, and educational designers to focus on performance expectancy, effort expectancy, social influence, habit, price value, and hedonic motivation when designing and adopting online learning apps for Saudi university students. KEYWORDS educational technology, m-learning, higher education, technology acceptance, Saudi Arabia","PeriodicalId":39024,"journal":{"name":"Scientific Journal of King Faisal University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75502585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Babeker, Z. Iqbal, S. Hamad, Hassan Medawi, R. Omer, Mohamed Al Saikhan
Valorisation of raw foods can substantially improve the resilience of the food chain, thereby mitigating the escalating food crisis. As date fruits contain most of the essential ingredients, it could serve as an unprecedented source of functional food production. This study aimed at valorising the commercially less valued date fruit, reziz, to prepare a carbonated drink. The collected reziz date fruit was subjected to date syrup (dibs) extraction using a specifically designed apparatus, Dibsi 10101, at 4 different pressures, 1000, -1.4, -2.8 and -5.5 millibar (mbar). However, the dibs extracted at -5.5 mbar yielded better clear dibs and thus was used in downstream production. Hulu-Mur (sweet and sour), a nutrient-rich flavouring agent derived from sorghum and Sudanese spices extract, was used as a favour enhancer. To produce the carbonated drink "Abridate," a different proportion of Hulu-Mur extract (1:5 w/v) and carbon dioxide were blended and subjected to a 10-point hedonic organoleptic evaluation. The results demonstrated that the superior Abridate was obtained by blending 6.89% of Hulu-Mur flavour extract with 11.8 TSS dibs at 4-bar carbon dioxide pressure. Abridate was comparable to commercially available carbonated beverages and held a substantial advantage over hazardous carbonated drinks due to its organic nature. KEYWORDS Abridate, carbonated drink, date palm, dibs, Hulu-Mur, reziz, soft drink
{"title":"Production of Carbonated Drink Using Reziz Date Dibs and Hulu-Mur Flavour","authors":"Mohamed Babeker, Z. Iqbal, S. Hamad, Hassan Medawi, R. Omer, Mohamed Al Saikhan","doi":"10.37575/b/agr/220008","DOIUrl":"https://doi.org/10.37575/b/agr/220008","url":null,"abstract":"Valorisation of raw foods can substantially improve the resilience of the food chain, thereby mitigating the escalating food crisis. As date fruits contain most of the essential ingredients, it could serve as an unprecedented source of functional food production. This study aimed at valorising the commercially less valued date fruit, reziz, to prepare a carbonated drink. The collected reziz date fruit was subjected to date syrup (dibs) extraction using a specifically designed apparatus, Dibsi 10101, at 4 different pressures, 1000, -1.4, -2.8 and -5.5 millibar (mbar). However, the dibs extracted at -5.5 mbar yielded better clear dibs and thus was used in downstream production. Hulu-Mur (sweet and sour), a nutrient-rich flavouring agent derived from sorghum and Sudanese spices extract, was used as a favour enhancer. To produce the carbonated drink \"Abridate,\" a different proportion of Hulu-Mur extract (1:5 w/v) and carbon dioxide were blended and subjected to a 10-point hedonic organoleptic evaluation. The results demonstrated that the superior Abridate was obtained by blending 6.89% of Hulu-Mur flavour extract with 11.8 TSS dibs at 4-bar carbon dioxide pressure. Abridate was comparable to commercially available carbonated beverages and held a substantial advantage over hazardous carbonated drinks due to its organic nature. KEYWORDS Abridate, carbonated drink, date palm, dibs, Hulu-Mur, reziz, soft drink","PeriodicalId":39024,"journal":{"name":"Scientific Journal of King Faisal University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69891764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hanan M Abd Elmoneim, Rehab J. Mohammed, Reda Abd El-Meguid, H. Tawfik, Manal Abd Elghany, Halah Albar, M. Basalamah, Nisreen D. M. Toni
The heterogeneity of ovarian cancer (Ov Ca) is attributed to multiple genetic and epigenetic changes, rendering it difficult to detect the most relevant molecular alterations. Identifying copy number variations (CNVs) will be helpful in screening patients with a familial history and will ultimately facilitate early diagnosis. This work aims to determine germline CNVs that may be associated with risks for different subtypes of ovarian cancer. Using Affymetrix genome-wide human SNP 6.0 arrays, 138 germline DNA samples of non-familial ovarian cancer were analysed using Golden Helix (SVS7) software. CNVs overlapping the EYA2 (20q13.12) and WNK1 (12p13.33) genes are the top hits with a significant p-value (<0.05). Deletion is more frequent in normal and low-grade carcinomas. Commonly, ovarian cancer is copy neutral (CN2) or has copy number gains (CN3). Amplification at these locations is associated with high-grade cases, which have worse overall survival rates. A CN3 in the WNK1 gene is associated with a higher expression of mRNA. It could be concluded that ovarian cancer is associated with CN3s where the segments of DNA overlap WNK1 and EYA2. The oncogenic effect of WNK1 and EYA2 on ovaries may serve as prognostic markers for ovarian cancer.
{"title":"Identifying Novel Targetable Chromosomal Alterations in Ovarian Cancer: Using Germline Copy Number Variation Association Analysis","authors":"Hanan M Abd Elmoneim, Rehab J. Mohammed, Reda Abd El-Meguid, H. Tawfik, Manal Abd Elghany, Halah Albar, M. Basalamah, Nisreen D. M. Toni","doi":"10.37575/b/med/220015","DOIUrl":"https://doi.org/10.37575/b/med/220015","url":null,"abstract":"The heterogeneity of ovarian cancer (Ov Ca) is attributed to multiple genetic and epigenetic changes, rendering it difficult to detect the most relevant molecular alterations. Identifying copy number variations (CNVs) will be helpful in screening patients with a familial history and will ultimately facilitate early diagnosis. This work aims to determine germline CNVs that may be associated with risks for different subtypes of ovarian cancer. Using Affymetrix genome-wide human SNP 6.0 arrays, 138 germline DNA samples of non-familial ovarian cancer were analysed using Golden Helix (SVS7) software. CNVs overlapping the EYA2 (20q13.12) and WNK1 (12p13.33) genes are the top hits with a significant p-value (<0.05). Deletion is more frequent in normal and low-grade carcinomas. Commonly, ovarian cancer is copy neutral (CN2) or has copy number gains (CN3). Amplification at these locations is associated with high-grade cases, which have worse overall survival rates. A CN3 in the WNK1 gene is associated with a higher expression of mRNA. It could be concluded that ovarian cancer is associated with CN3s where the segments of DNA overlap WNK1 and EYA2. The oncogenic effect of WNK1 and EYA2 on ovaries may serve as prognostic markers for ovarian cancer.","PeriodicalId":39024,"journal":{"name":"Scientific Journal of King Faisal University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69893714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ammar H. Alsughayir, Mohrah Alalshaikh, Yasser Almaki, Leenah Almass, Mohammed Alnamnakani, Imran Pukhta, Alyazeed Alsaif, Sarah Abo Baker, Abdullah Albarghash
Although blood transfusion is a life-saving procedure, it can be associated with complications in rare cases. An acute transfusion reaction (ATR) is a complication where recipients exhibit an adverse reaction within 24 hours of a blood transfusion. This study aimed to determine the incidence of ATRs. This retrospective study reviewed the ATRs for all patients who received blood products over three years (2018, 2019, 2020). Of 81,498 transfusion episodes investigated, 132 (0.16%) were associated with ATRs. The most frequent adverse reactions were allergic reactions (62.9%, n = 83), followed by febrile non-haemolytic transfusion reactions (FNHTR) (32.6%, n = 43). Among blood products, it was found that allergic reactions were associated with platelet transfusions (40.9%, n = 34) and FNHTR with packed red blood cell transfusions (79.0%, n = 34). Serious complications such as acute haemolytic transfusion reaction and transfusion-related lung injury were not reported. The low percentage of recorded ATRs may indicate an underestimation of the true incidence due to under-reporting. Accurate reporting of ATRs is a crucial element of the haemovigilance system and would improve blood transfusion safety and enhance patient management. KEYWORDS FNHTR; allergic reactions; TACO; haemovigilance; urticarial rash
{"title":"Acute Transfusion Reactions in a Tertiary Care Hospital: The Saudi Context","authors":"Ammar H. Alsughayir, Mohrah Alalshaikh, Yasser Almaki, Leenah Almass, Mohammed Alnamnakani, Imran Pukhta, Alyazeed Alsaif, Sarah Abo Baker, Abdullah Albarghash","doi":"10.37575/b/med/220034","DOIUrl":"https://doi.org/10.37575/b/med/220034","url":null,"abstract":"Although blood transfusion is a life-saving procedure, it can be associated with complications in rare cases. An acute transfusion reaction (ATR) is a complication where recipients exhibit an adverse reaction within 24 hours of a blood transfusion. This study aimed to determine the incidence of ATRs. This retrospective study reviewed the ATRs for all patients who received blood products over three years (2018, 2019, 2020). Of 81,498 transfusion episodes investigated, 132 (0.16%) were associated with ATRs. The most frequent adverse reactions were allergic reactions (62.9%, n = 83), followed by febrile non-haemolytic transfusion reactions (FNHTR) (32.6%, n = 43). Among blood products, it was found that allergic reactions were associated with platelet transfusions (40.9%, n = 34) and FNHTR with packed red blood cell transfusions (79.0%, n = 34). Serious complications such as acute haemolytic transfusion reaction and transfusion-related lung injury were not reported. The low percentage of recorded ATRs may indicate an underestimation of the true incidence due to under-reporting. Accurate reporting of ATRs is a crucial element of the haemovigilance system and would improve blood transfusion safety and enhance patient management. KEYWORDS FNHTR; allergic reactions; TACO; haemovigilance; urticarial rash","PeriodicalId":39024,"journal":{"name":"Scientific Journal of King Faisal University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69893828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Khelil, Alla Eddine Khelil, T. Bouzir, D. Berkouk, N. Zemmouri
Building skins have a vital role in energy efficiency, particularly in terms of the conservation or consumption of energy. Many factors must be considered by designers to prevent wasting significant quantities of energy, to preserve and provide internal air conditioning and lighting, particularly in hot dry locations where the integration of sun protection systems is highly recommended. This pilot study looks at the challenge of developing energy-efficient building skins in hot regions like Biskra city by applying a natural daylight strategy represented by a parameterised moveable shading component to the skin of a hospital patient’s room. In this research, we aim to assess the adoption of building skin parameterisation as a beneficial technique for reducing energy consumption and improving internal temperature and lighting in this environment by developing and implementing a computational design methodology. Promising experimental results demonstrate the benefit of this proposal. The use of parameterisation in the design of patient’s room skins, with moveable, tightly folded morphology, providing self-shading, are essential and effective techniques for ensuring good natural lighting and reducing both temperature and energy consumption..
{"title":"Assessing the Effect of Building Skin Adaptability on Energy Consumption in Hot Arid Regions","authors":"S. Khelil, Alla Eddine Khelil, T. Bouzir, D. Berkouk, N. Zemmouri","doi":"10.37575/b/sci/210082","DOIUrl":"https://doi.org/10.37575/b/sci/210082","url":null,"abstract":"Building skins have a vital role in energy efficiency, particularly in terms of the conservation or consumption of energy. Many factors must be considered by designers to prevent wasting significant quantities of energy, to preserve and provide internal air conditioning and lighting, particularly in hot dry locations where the integration of sun protection systems is highly recommended. This pilot study looks at the challenge of developing energy-efficient building skins in hot regions like Biskra city by applying a natural daylight strategy represented by a parameterised moveable shading component to the skin of a hospital patient’s room. In this research, we aim to assess the adoption of building skin parameterisation as a beneficial technique for reducing energy consumption and improving internal temperature and lighting in this environment by developing and implementing a computational design methodology. Promising experimental results demonstrate the benefit of this proposal. The use of parameterisation in the design of patient’s room skins, with moveable, tightly folded morphology, providing self-shading, are essential and effective techniques for ensuring good natural lighting and reducing both temperature and energy consumption..","PeriodicalId":39024,"journal":{"name":"Scientific Journal of King Faisal University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69894818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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