Endometriosis is a chronic gynecological disorder characterized by the aberrant growth of endometrial tissue outside the uterus, resulting in severe pain and infertility. Conventional treatments often come with limitations and side effects, prompting a quest for alternative therapies. Medicinal plants, integral to traditional medicine systems, have emerged as potential solutions. This review delves into the phytopharmacology and chemistry of medicinal plants employed in endometriosis treatment. An exhaustive search revealed pertinent studies concerning medicinal plant use in endometriosis treatment. These studies were scrutinized for their phytopharmacological attributes and active chemical constituents. Numerous medicinal plants exhibited anti-inflammatory, analgesic, antioxidant, immunomodulatory, and hormone-regulating properties, pivotal in endometriosis management. Mechanisms encompassed the suppression of inflammatory mediators, modulation of estrogen signaling, mitigation of oxidative stress, and enhancement of immune function. Furthermore, key chemical constituents responsible for these effects were pinpointed and classified into classes such as flavonoids, terpenoids, alkaloids, and phenolic compounds. These bioactive agents elicited their actions via diverse molecular targets, including cyclooxygenase enzymes, estrogen receptors, nuclear factor-kappa B, and reactive oxygen species. The findings underscore the potential of medicinal plants as adjunct therapies for endometriosis. Nonetheless, additional preclinical and clinical investigations are imperative to substantiate their efficacy, safety, and optimal dosing. Grasping the phytopharmacology and chemistry of medicinal plants in endometriosis treatment lays the groundwork for novel therapeutic agent development, spotlighting the capacity of natural products to combat this intricate gynecological ailment.
子宫内膜异位症是一种慢性妇科疾病，其特点是子宫内膜组织在子宫腔外异常生长，导致剧烈疼痛和不孕。传统疗法往往存在局限性和副作用，因此人们开始寻求替代疗法。传统医学体系中不可或缺的药用植物已成为潜在的解决方案。这篇综述深入探讨了用于治疗子宫内膜异位症的药用植物的植物药理学和化学。通过详尽的检索，发现了有关药用植物用于子宫内膜异位症治疗的相关研究。研究人员仔细研究了这些研究的植物药理学特性和活性化学成分。许多药用植物具有抗炎、镇痛、抗氧化、免疫调节和激素调节特性，在子宫内膜异位症的治疗中发挥着关键作用。其机制包括抑制炎症介质、调节雌激素信号、减轻氧化应激和增强免疫功能。此外，还确定了产生这些作用的主要化学成分，并将其分为黄酮类、萜类、生物碱和酚类化合物等类别。这些生物活性物质通过不同的分子靶点发挥作用，包括环氧化酶、雌激素受体、核因子卡巴 B 和活性氧。这些发现强调了药用植物作为子宫内膜异位症辅助疗法的潜力。尽管如此，要证实药用植物的疗效、安全性和最佳剂量，还必须进行更多的临床前和临床研究。掌握药用植物在子宫内膜异位症治疗中的植物药理学和化学性质，为新型治疗药物的开发奠定了基础，同时也凸显了天然产品对抗这种复杂妇科疾病的能力。
{"title":"Indian Medicinal Plants for the Management of Endometriosis: A Comprehensive Review on their phytopharmacology","authors":"Rustam Ekbbal, Aakash Kumar Jaiswal, Mansi Aggarwal, Mhaveer Singh, Sayad Ahad Ali, Shadab Ali, Gaurav Gautam","doi":"10.53365/nrfhh/174668","DOIUrl":"https://doi.org/10.53365/nrfhh/174668","url":null,"abstract":"Endometriosis is a chronic gynecological disorder characterized by the aberrant growth of endometrial tissue outside the uterus, resulting in severe pain and infertility. Conventional treatments often come with limitations and side effects, prompting a quest for alternative therapies. Medicinal plants, integral to traditional medicine systems, have emerged as potential solutions. This review delves into the phytopharmacology and chemistry of medicinal plants employed in endometriosis treatment. An exhaustive search revealed pertinent studies concerning medicinal plant use in endometriosis treatment. These studies were scrutinized for their phytopharmacological attributes and active chemical constituents. Numerous medicinal plants exhibited anti-inflammatory, analgesic, antioxidant, immunomodulatory, and hormone-regulating properties, pivotal in endometriosis management. Mechanisms encompassed the suppression of inflammatory mediators, modulation of estrogen signaling, mitigation of oxidative stress, and enhancement of immune function. Furthermore, key chemical constituents responsible for these effects were pinpointed and classified into classes such as flavonoids, terpenoids, alkaloids, and phenolic compounds. These bioactive agents elicited their actions via diverse molecular targets, including cyclooxygenase enzymes, estrogen receptors, nuclear factor-kappa B, and reactive oxygen species. The findings underscore the potential of medicinal plants as adjunct therapies for endometriosis. Nonetheless, additional preclinical and clinical investigations are imperative to substantiate their efficacy, safety, and optimal dosing. Grasping the phytopharmacology and chemistry of medicinal plants in endometriosis treatment lays the groundwork for novel therapeutic agent development, spotlighting the capacity of natural products to combat this intricate gynecological ailment.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"78 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138978639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vino Palani, B. Balasubramanian, Santhosh Chinnaraj, Viji Maluventhen, V. Arumugam, Wen-Chao Liu, M. Arumugam
To evaluate the quality control parameters of Goniothalamus wightii leaves, which are used for traditional medicine. The leaves extracts were characterized and to evaluate the phytochemical composition, antibacterial, antibiofilm and antioxidant activities. The macroscopic studies of the leaves are simply arranged, green color and dicot plant. The physico-chemical values are the presence of foreign matter, loss on drying, moisture and tannin content, no swelling and foaming capacity. Total ash, acid-insoluble ash, water soluble ash, and sulphated ash are the ash values; extractive values are examined in various organic solvents with visualized UV to exhibit various color variations. The proximate compositions were fiber, soluble and insoluble fiber, carbohydrates, and lipid content presence at g/100g. The quantitative phytoconstituents presence of hexane, ethyl acetate and methanol extracts such as were resolved in sequential extraction with hexane, chloroform, ethyl acetate, and methanol bands were separated. The FT-IR spectrum resembles the aliphatic and aromatic amines, and the LC-MS were identified by phenolic and flavonoids derivatives, steroids, lignin’s. The compounds based the antioxidant activities were 50-80% inhibition against the free radicals and antibacterial, antibiofilm activities were strongly killed the pathogens (E. coli, E. faecalis). In concluded that the pharmacognostic standardization is the first report in these species. The extracts of G. wightiii have potential antioxidant, antibacterial and antibiofilm effects, which could lead to pharmaceutical and industrial applications.
{"title":"Pharmacognostic, characterization, physio-chemical scrutinizes, and biological attributes of Goniothalamus wightii","authors":"Vino Palani, B. Balasubramanian, Santhosh Chinnaraj, Viji Maluventhen, V. Arumugam, Wen-Chao Liu, M. Arumugam","doi":"10.53365/nrfhh/174301","DOIUrl":"https://doi.org/10.53365/nrfhh/174301","url":null,"abstract":"To evaluate the quality control parameters of Goniothalamus wightii leaves, which are used for traditional medicine. The leaves extracts were characterized and to evaluate the phytochemical composition, antibacterial, antibiofilm and antioxidant activities. The macroscopic studies of the leaves are simply arranged, green color and dicot plant. The physico-chemical values are the presence of foreign matter, loss on drying, moisture and tannin content, no swelling and foaming capacity. Total ash, acid-insoluble ash, water soluble ash, and sulphated ash are the ash values; extractive values are examined in various organic solvents with visualized UV to exhibit various color variations. The proximate compositions were fiber, soluble and insoluble fiber, carbohydrates, and lipid content presence at g/100g. The quantitative phytoconstituents presence of hexane, ethyl acetate and methanol extracts such as were resolved in sequential extraction with hexane, chloroform, ethyl acetate, and methanol bands were separated. The FT-IR spectrum resembles the aliphatic and aromatic amines, and the LC-MS were identified by phenolic and flavonoids derivatives, steroids, lignin’s. The compounds based the antioxidant activities were 50-80% inhibition against the free radicals and antibacterial, antibiofilm activities were strongly killed the pathogens (E. coli, E. faecalis). In concluded that the pharmacognostic standardization is the first report in these species. The extracts of G. wightiii have potential antioxidant, antibacterial and antibiofilm effects, which could lead to pharmaceutical and industrial applications.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"129 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139247082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amit Zinabhai Chaudhari, Riyansi Satasia, Maulikkumar D. Vaja, Kishan Patel
The human body synthesizes the provitamin coenzyme Q10 (CoQ10), which plays a crucial role in the electron transport chain by ensuring a consistent and sufficient energy supply. CoQ10 exhibits multiple cellular roles, including its involvement in mitochondrial function, numerous cellular compartments, and plasma lipoproteins. Furthermore, CoQ10 plays a crucial role as an important antioxidant. The chemical composition of CoQ10 exhibits a strong correlation with vitamin K. It consists of a benzoquinone ring serving as the head group, accompanied by a tail made of ten isoprene units. A lack of CoQ10 has been identified as a fundamental factor contributing to numerous age-related and chronic illness problems. The efficacy of CoQ10 in various medical conditions has been proved by empirical evidence. Numerous research trials are now investigating the therapeutic and nutritional potential of CoQ10. CoQ10 continues to be predominantly utilized in the realm of cardiac research and reproductive treatments. However, there has been a notable surge of interest in exploring novel applications, notably in the context of topical administration.
{"title":"Coenzyme q10 in cardiovascular disease: an insight for a potential therapeutic benefit","authors":"Amit Zinabhai Chaudhari, Riyansi Satasia, Maulikkumar D. Vaja, Kishan Patel","doi":"10.53365/nrfhh/174300","DOIUrl":"https://doi.org/10.53365/nrfhh/174300","url":null,"abstract":"The human body synthesizes the provitamin coenzyme Q10 (CoQ10), which plays a crucial role in the electron transport chain by ensuring a consistent and sufficient energy supply. CoQ10 exhibits multiple cellular roles, including its involvement in mitochondrial function, numerous cellular compartments, and plasma lipoproteins. Furthermore, CoQ10 plays a crucial role as an important antioxidant. The chemical composition of CoQ10 exhibits a strong correlation with vitamin K. It consists of a benzoquinone ring serving as the head group, accompanied by a tail made of ten isoprene units. A lack of CoQ10 has been identified as a fundamental factor contributing to numerous age-related and chronic illness problems. The efficacy of CoQ10 in various medical conditions has been proved by empirical evidence. Numerous research trials are now investigating the therapeutic and nutritional potential of CoQ10. CoQ10 continues to be predominantly utilized in the realm of cardiac research and reproductive treatments. However, there has been a notable surge of interest in exploring novel applications, notably in the context of topical administration.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"34 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139246695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Paul, Tchobsala, Beyang Ware Guidakre, H. Gilbert, D. D. Danra, Souare Konksala
A study was carried out on the phytodiversity and the sustainable management situation of reforested sites in order to ameliorate the living conditions of the local population of three villages (Kilguim, Going I and Going II) of Kaélé in the Mayo-Kani division. The semi-structured and structured maintenance beside the 200 persons and the registration of the vegetation was done in three villages. Findings revealed higher bushfires practice in sites. Data analysis proved that the practice of bushfires in forbidden or restricted sites (83.50 ± 16.01), the lack of plausibility studies of reforestation projects associating local populations (78.50 ± 13.99), insufficiency of bore holes for constant water supply for the follow up of the reforestation (76.00 ± 19.10), lack of specialized structures in the reforestation domain (72.83 ± 13.03), the insufficiency of sensitization on the importance of reforestation (71.67 ± 27.55) and the cutting of wood (68.00 ± 12.17) are real problems that the reforestation sites faces. The confiscation of land for reforestation without any alternative measure taken for the assurance of alimentary security and firewood of the population is the major cause of the dissatisfaction of the riverine population. The death rate is pretty elevated in the Kilguim site (15%) because of the lack of maintenance in reforested sites. The Shannon index is very high in the Going I site (2.71bits) because it is less perturbed by anthropic activities. Vegetation presents a structure in the form of a bell or cloche in prohibited sites translate a heterogeneity of the milieu because of anthropic perturbations. The durable management plan was opted for the management of reforestation sites.
{"title":"Phytodiversity and sustainable Management status of Reforested Sites of the Soudano-Sahelian Zone of Cameroon","authors":"K. Paul, Tchobsala, Beyang Ware Guidakre, H. Gilbert, D. D. Danra, Souare Konksala","doi":"10.53365/nrfhh/171902","DOIUrl":"https://doi.org/10.53365/nrfhh/171902","url":null,"abstract":"A study was carried out on the phytodiversity and the sustainable management situation of reforested sites in order to ameliorate the living conditions of the local population of three villages (Kilguim, Going I and Going II) of Kaélé in the Mayo-Kani division. The semi-structured and structured maintenance beside the 200 persons and the registration of the vegetation was done in three villages. Findings revealed higher bushfires practice in sites. Data analysis proved that the practice of bushfires in forbidden or restricted sites (83.50 ± 16.01), the lack of plausibility studies of reforestation projects associating local populations (78.50 ± 13.99), insufficiency of bore holes for constant water supply for the follow up of the reforestation (76.00 ± 19.10), lack of specialized structures in the reforestation domain (72.83 ± 13.03), the insufficiency of sensitization on the importance of reforestation (71.67 ± 27.55) and the cutting of wood (68.00 ± 12.17) are real problems that the reforestation sites faces. The confiscation of land for reforestation without any alternative measure taken for the assurance of alimentary security and firewood of the population is the major cause of the dissatisfaction of the riverine population. The death rate is pretty elevated in the Kilguim site (15%) because of the lack of maintenance in reforested sites. The Shannon index is very high in the Going I site (2.71bits) because it is less perturbed by anthropic activities. Vegetation presents a structure in the form of a bell or cloche in prohibited sites translate a heterogeneity of the milieu because of anthropic perturbations. The durable management plan was opted for the management of reforestation sites.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139247125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dhansri Bhupathie, Sathish Kumar M, Kannan R. R. Rengasamy
Cardiovascular death remains the top causes of death, and one of the main risk factors associated with cardiovascular diseases are Atherosclerosis and Type 2 Diabetes Mellitus. The associated conspiracy was high because of the failure of the complete regulatory network rather than a single gene or protein malfunction, so one-target one drug fails for complete eradication of the disease. Natural compounds had the potency to act upon various targets to elucidate complete therapeutic effects. In traditional medicines, Nelumbinis semen or lotus seeds were used in treating multiple diseases and as a functional food. In the world of drug discovery, the idea of creating multi-target medications against complicated conditions is gaining momentum. To understand the mechanism emphasized by the therapeutic effect of Nelumbinis semen or lotus seeds, which act upon various targets and elucidate cumulative activity in Atherosclerosis and Type 2 Diabetes Mellitus. The bioactive components and their targets were obtained, and common targets associated with atherosclerosis and type 2 diabetes mellitus were taken. The network was constructed using Cytoscape 3.9.1 software. The protein-protein interaction was analysed using the STRING database. Gene and pathway enrichment was performed using ShinyGo 0.77 software. The pathway associated with the diseases and no of genes involved were studied. The active compounds of the lotus seed are Myricetin, Quercetin, Isofucosterol, Rhamnetin, Myristic acid, etc. The main and active targets for lotus seeds were PPARα, INSR, HMGCR and NCp1L1. The key biological pathways by which the compound elucidates therapeutic effects are Diabetic cardiomyopathy and Terpenoid backbone biosynthesis.
{"title":"A comprehensive network pharmacology study of Nelumbinis semen (Lotus Seeds) phytochemicals for Atherosclerosis and Type 2 Diabetes Mellitus","authors":"Dhansri Bhupathie, Sathish Kumar M, Kannan R. R. Rengasamy","doi":"10.53365/nrfhh/175559","DOIUrl":"https://doi.org/10.53365/nrfhh/175559","url":null,"abstract":"Cardiovascular death remains the top causes of death, and one of the main risk factors associated with cardiovascular diseases are Atherosclerosis and Type 2 Diabetes Mellitus. The associated conspiracy was high because of the failure of the complete regulatory network rather than a single gene or protein malfunction, so one-target one drug fails for complete eradication of the disease. Natural compounds had the potency to act upon various targets to elucidate complete therapeutic effects. In traditional medicines, Nelumbinis semen or lotus seeds were used in treating multiple diseases and as a functional food. In the world of drug discovery, the idea of creating multi-target medications against complicated conditions is gaining momentum. To understand the mechanism emphasized by the therapeutic effect of Nelumbinis semen or lotus seeds, which act upon various targets and elucidate cumulative activity in Atherosclerosis and Type 2 Diabetes Mellitus. The bioactive components and their targets were obtained, and common targets associated with atherosclerosis and type 2 diabetes mellitus were taken. The network was constructed using Cytoscape 3.9.1 software. The protein-protein interaction was analysed using the STRING database. Gene and pathway enrichment was performed using ShinyGo 0.77 software. The pathway associated with the diseases and no of genes involved were studied. The active compounds of the lotus seed are Myricetin, Quercetin, Isofucosterol, Rhamnetin, Myristic acid, etc. The main and active targets for lotus seeds were PPARα, INSR, HMGCR and NCp1L1. The key biological pathways by which the compound elucidates therapeutic effects are Diabetic cardiomyopathy and Terpenoid backbone biosynthesis.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139251326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wuhan, China reported a novel coronavirus-related sickness in late 2019, which quickly spread into a global epidemic. One crucial factor in combating the coronavirus infection appears to be the presence of a robust, long-lasting, and active immune system. The immune response is affected by several factors, including food. Nutritional insufficiency can cause immune deficits, making infections more likely to cause fatality. Thus, understanding numerous behaviors, particularly dietary habits, is essential to determining their capacity to reduce severe acute respiratory syndrome coronavirus 2 risks and improve prognosis. In this paper, the authors summarize the complex interaction between nutritional status and severe acute respiratory syndrome corona virus 2 infections, as well as the consequences of poor nutrients with regard of the extent to which disease is affected. The literature was compiled by searching a number of reputable scientific databases including Scopus, Science Direct, Springer, Nature, PubMed, Web of Science resources. The accumulating evidence demonstrates that malnutrition impairs the immune system's ability to function, weakening the body's infection resistance. This review emphasizes the significance of nutritional status in the care of coronavirus disease patients as well as demonstrates that functional foods may contribute to better outcomes. Ageing, Obesity, Malnutrition, Undernutrition, Lack of exercise are having a devastating effect on people's health in general and during this coronavirus disease. The severity and prognosis of coronavirus illness seem to be significantly influenced by lifestyle choices, nutritional imbalances, and impaired immune response.
2019 年底，中国武汉报告了一种新型冠状病毒相关疾病，并迅速蔓延成全球性流行病。抗击冠状病毒感染的一个关键因素似乎是存在一个强大、持久和活跃的免疫系统。免疫反应受多种因素影响，包括食物。营养不足会导致免疫缺陷，使感染更有可能导致死亡。因此，了解众多行为，尤其是饮食习惯，对于确定其降低严重急性呼吸系统综合征冠状病毒 2 风险和改善预后的能力至关重要。在本文中，作者总结了营养状况与严重急性呼吸综合征冠状病毒 2 感染之间复杂的相互作用，以及营养不良对疾病影响程度的后果。通过检索 Scopus、Science Direct、Springer、Nature、PubMed 和 Web of Science 等多个著名科学数据库，对文献进行了汇编。不断积累的证据表明，营养不良会损害免疫系统的功能，削弱人体的抗感染能力。本综述强调了营养状况在冠状病毒病患护理中的重要性，并说明功能性食品可能有助于改善疗效。老龄化、肥胖、营养不良、营养不足、缺乏运动对人们的整体健康和冠状病毒疾病都有破坏性影响。冠状病毒疾病的严重程度和预后似乎在很大程度上受到生活方式选择、营养失衡和免疫反应受损的影响。
{"title":"A Concise Review: Nutritional Interventions for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)","authors":"P. Dhakad, Raghav Mishra, Isha Mishra","doi":"10.53365/nrfhh/175070","DOIUrl":"https://doi.org/10.53365/nrfhh/175070","url":null,"abstract":"Wuhan, China reported a novel coronavirus-related sickness in late 2019, which quickly spread into a global epidemic. One crucial factor in combating the coronavirus infection appears to be the presence of a robust, long-lasting, and active immune system. The immune response is affected by several factors, including food. Nutritional insufficiency can cause immune deficits, making infections more likely to cause fatality. Thus, understanding numerous behaviors, particularly dietary habits, is essential to determining their capacity to reduce severe acute respiratory syndrome coronavirus 2 risks and improve prognosis. In this paper, the authors summarize the complex interaction between nutritional status and severe acute respiratory syndrome corona virus 2 infections, as well as the consequences of poor nutrients with regard of the extent to which disease is affected. The literature was compiled by searching a number of reputable scientific databases including Scopus, Science Direct, Springer, Nature, PubMed, Web of Science resources. The accumulating evidence demonstrates that malnutrition impairs the immune system's ability to function, weakening the body's infection resistance. This review emphasizes the significance of nutritional status in the care of coronavirus disease patients as well as demonstrates that functional foods may contribute to better outcomes. Ageing, Obesity, Malnutrition, Undernutrition, Lack of exercise are having a devastating effect on people's health in general and during this coronavirus disease. The severity and prognosis of coronavirus illness seem to be significantly influenced by lifestyle choices, nutritional imbalances, and impaired immune response.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"32 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139261195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Edo, Prince Samuel, Gift Onyinyechi Oloni, Gracious Okeoghene Ezekiel, Favour Ogheneoruese Onoharigho, Ogheneochuko Oghenegueke, Susan Chinedu Nwachukwu, Opiti Ajiri Rapheal, Mercy Orezimena Ajokpaoghene, Michael Chukwuma Okolie, Ruth Sheyi Ajakaye, Winifred Ndudi, Philip chukwuemeziozor Igbodo
Cocoa (Theobroma cacao) is a well-known tropical plant extensively cultivated for its beans, which are the primary raw material for chocolate production. This article aims to comprehensively review and analyze the bioactive compounds present in cocoa and their corresponding biological activities, highlighting their potential implications for human health. A systematic literature review was conducted to gather relevant research articles and reviews related to the bioactive compounds of cocoa and their biological activities. The databases used for the search included PubMed, Scopus, and Google Scholar, with keywords such as "cocoa bioactive compounds," "flavonoids," "theobromine," "antioxidant activity," and "cardiovascular health" used for data retrieval. The analysis revealed that cocoa is rich in bioactive compounds, such as flavonoids (e.g., catechins, epicatechins), methylxanthines (e.g., theobromine, caffeine), and polyphenols. These bioactive compounds have been associated with various biological activities, including potent antioxidant effects, anti-inflammatory properties, and vasodilation, which may positively influence cardiovascular health. The consumption of cocoa and its bioactive compounds may offer several health benefits due to their antioxidant, anti-inflammatory, and cardiovascular-protective properties. However, further research is necessary to fully understand the mechanisms of action and to determine appropriate dosage recommendations for harnessing the potential health benefits of cocoa.
可可（Theobroma cacao）是一种著名的热带植物，因其可可豆而被广泛种植，可可豆是生产巧克力的主要原料。本文旨在全面回顾和分析可可中的生物活性化合物及其相应的生物活性，突出它们对人类健康的潜在影响。为了收集与可可生物活性化合物及其生物活性相关的研究文章和综述，我们进行了系统的文献综述。用于检索的数据库包括 PubMed、Scopus 和 Google Scholar，检索时使用了 "可可生物活性化合物"、"类黄酮"、"可可碱"、"抗氧化活性 "和 "心血管健康 "等关键词。分析表明，可可含有丰富的生物活性化合物，如类黄酮（如儿茶素、表儿茶素）、甲基黄嘌呤（如可可碱、咖啡因）和多酚。这些生物活性化合物具有多种生物活性，包括强大的抗氧化作用、抗炎特性和血管扩张作用，可对心血管健康产生积极影响。由于可可及其生物活性化合物具有抗氧化、抗炎和保护心血管的特性，因此食用可可及其生物活性化合物可为健康带来多种益处。然而，要充分了解可可的作用机制并确定适当的用量建议，以利用可可的潜在健康益处，还需要进一步的研究。
{"title":"Review on the Biological and Bioactive components of Cocoa (Theobroma Cacao). Insight on Food, Health and Nutrition","authors":"G. Edo, Prince Samuel, Gift Onyinyechi Oloni, Gracious Okeoghene Ezekiel, Favour Ogheneoruese Onoharigho, Ogheneochuko Oghenegueke, Susan Chinedu Nwachukwu, Opiti Ajiri Rapheal, Mercy Orezimena Ajokpaoghene, Michael Chukwuma Okolie, Ruth Sheyi Ajakaye, Winifred Ndudi, Philip chukwuemeziozor Igbodo","doi":"10.53365/nrfhh/174302","DOIUrl":"https://doi.org/10.53365/nrfhh/174302","url":null,"abstract":"Cocoa (Theobroma cacao) is a well-known tropical plant extensively cultivated for its beans, which are the primary raw material for chocolate production. This article aims to comprehensively review and analyze the bioactive compounds present in cocoa and their corresponding biological activities, highlighting their potential implications for human health. A systematic literature review was conducted to gather relevant research articles and reviews related to the bioactive compounds of cocoa and their biological activities. The databases used for the search included PubMed, Scopus, and Google Scholar, with keywords such as \"cocoa bioactive compounds,\" \"flavonoids,\" \"theobromine,\" \"antioxidant activity,\" and \"cardiovascular health\" used for data retrieval. The analysis revealed that cocoa is rich in bioactive compounds, such as flavonoids (e.g., catechins, epicatechins), methylxanthines (e.g., theobromine, caffeine), and polyphenols. These bioactive compounds have been associated with various biological activities, including potent antioxidant effects, anti-inflammatory properties, and vasodilation, which may positively influence cardiovascular health. The consumption of cocoa and its bioactive compounds may offer several health benefits due to their antioxidant, anti-inflammatory, and cardiovascular-protective properties. However, further research is necessary to fully understand the mechanisms of action and to determine appropriate dosage recommendations for harnessing the potential health benefits of cocoa.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"22 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139261420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Edo, Patrick Othuke Akpoghelie, Agatha Ngukuran Jikah, Favour Ogheneoruese Onoharigho, J. O. Owheruo, K. A. Okoronkwo
One of the most important foods produced and consumed worldwide is natural honey. This substance features nice sensory qualities such as a light hue as well as a familiar scent and flavor. It also contains organic acids, sugars, minerals, enzymes, phenolic and volatile chemicals, methylglyoxal, amino acids, vitamins etcetera which have been linked to potential biological activities. All of these features make this viscous substance extremely desirable by consumers thus raising its market value. Natural honey is however prone to contamination upon improper storage so that its natural quality and authenticity can be jeopardized. In this regard, the purpose of this study is to provide updates to the literature available on the physicochemical, sensory features, content, economic value, medicinal benefits, contamination, originality, and adulteration of natural honey. With this context, we hope to provide data that can help guide future honey study.
{"title":"Quality, composition and health effects of natural honey: a review","authors":"G. Edo, Patrick Othuke Akpoghelie, Agatha Ngukuran Jikah, Favour Ogheneoruese Onoharigho, J. O. Owheruo, K. A. Okoronkwo","doi":"10.53365/nrfhh/174739","DOIUrl":"https://doi.org/10.53365/nrfhh/174739","url":null,"abstract":"One of the most important foods produced and consumed worldwide is natural honey. This substance features nice sensory qualities such as a light hue as well as a familiar scent and flavor. It also contains organic acids, sugars, minerals, enzymes, phenolic and volatile chemicals, methylglyoxal, amino acids, vitamins etcetera which have been linked to potential biological activities. All of these features make this viscous substance extremely desirable by consumers thus raising its market value. Natural honey is however prone to contamination upon improper storage so that its natural quality and authenticity can be jeopardized. In this regard, the purpose of this study is to provide updates to the literature available on the physicochemical, sensory features, content, economic value, medicinal benefits, contamination, originality, and adulteration of natural honey. With this context, we hope to provide data that can help guide future honey study.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"226 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139260977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial: Bioactive compounds in chronic and infectious disease","authors":"Vivek P. Chavda, Pankti C Balar","doi":"10.53365/nrfhh/169990","DOIUrl":"https://doi.org/10.53365/nrfhh/169990","url":null,"abstract":"Not Applicable","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"483 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116602475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Ibrahim, Shabina Khan, S. Pathak, M. Mazhar, Harpreet Singh
Vitamins are essential for a healthy life. Compared to other nutrients, the body needs them in very small amounts. B vitamins, often known as the vitamin B complex, are a class of water-soluble vitamins with key functions in cellular metabolism. Thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), pantothenic acid (vitamin B5), pyridoxine (vitamin B6), biotin (vitamin B7), folate (vitamin B9), often known as folic acid, and cobalamin (vitamin B12) are the eight distinct vitamins that collectively constitute the vitamin B complex. The body's energy levels, cognitive activity, and cell metabolism are all directly impacted by B vitamins. Four main factors contribute to vitamin B deficiency: an unbalanced diet, excessive alcohol intake, different drugs, and disorders that induce gut malabsorption. If these B vitamin deficiencies are left untreated, they can eventually cause symptoms such as peripheral neuropathy, heart attacks, strokes etc. B vitamins are present in natural, whole foods. Compared to their unprocessed counterparts, white flour and other processed carbohydrates like sugar often contain fewer B vitamins. Excellent sources of vitamins Bs comprise legumes (beans or pulses), potatoes, bananas, whole grains, tempeh, chilli peppers, brewer's yeast, nutritional yeast, and molasses. This paper provides an in-depth summary of the most popular types of vitamin B, emphasizing why the body needs them, the symptoms of a deficiency, and what diet or foods are rich in them.
{"title":"Vitamin B-Complex and its Relationship with the Health of Vegetarian People","authors":"M. Ibrahim, Shabina Khan, S. Pathak, M. Mazhar, Harpreet Singh","doi":"10.53365/nrfhh/169824","DOIUrl":"https://doi.org/10.53365/nrfhh/169824","url":null,"abstract":"Vitamins are essential for a healthy life. Compared to other nutrients, the body needs them in very small amounts. B vitamins, often known as the vitamin B complex, are a class of water-soluble vitamins with key functions in cellular metabolism. Thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), pantothenic acid (vitamin B5), pyridoxine (vitamin B6), biotin (vitamin B7), folate (vitamin B9), often known as folic acid, and cobalamin (vitamin B12) are the eight distinct vitamins that collectively constitute the vitamin B complex. The body's energy levels, cognitive activity, and cell metabolism are all directly impacted by B vitamins. Four main factors contribute to vitamin B deficiency: an unbalanced diet, excessive alcohol intake, different drugs, and disorders that induce gut malabsorption. If these B vitamin deficiencies are left untreated, they can eventually cause symptoms such as peripheral neuropathy, heart attacks, strokes etc. B vitamins are present in natural, whole foods. Compared to their unprocessed counterparts, white flour and other processed carbohydrates like sugar often contain fewer B vitamins. Excellent sources of vitamins Bs comprise legumes (beans or pulses), potatoes, bananas, whole grains, tempeh, chilli peppers, brewer's yeast, nutritional yeast, and molasses. This paper provides an in-depth summary of the most popular types of vitamin B, emphasizing why the body needs them, the symptoms of a deficiency, and what diet or foods are rich in them.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129113554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：