Elham A.M Kheir, Adil A Elhussein, Gihan O.M El hassan, S. Yagi
This study aimed to screen the phenolic profile, antimicrobial and antiradical activities of endophytic fungi residing in the tissues of Acacia nilotica grown in Sudan. Isolates of endophytic fungi were isolated from fruit, leaf and twig. Methanolic extracts were prepared by maceration. Antimicrobial activity was determined by the disc diffusion method. Antiradical activity was evaluated by the 1, 1-diphenyl-2-picryl hydrazyl (DPPH) assay. Ten endophytic fungi were recovered from the twig (6), leaf (2) and fruit (2) of A. nilotica. Extracts revealed better antifungal activity, with isolates T3, L1 and F1 exerting the highest inhibition zones (20.6, 20 and 18.3 mm, respectively) against Aspergillus niger. Isolates T4 and T5 revealed the highest antiradical effect with IC50 values of 302 and 478 µg/mL respectively. Chemical analysis revealed that gallic acid and naringenin were the dominant compounds. Their pattern divided the endophytic fungi into two categories; gallic acid- rich endophytes including isolates L1 and L2 (isolated from the leaf) as well as isolates T4 and T2 (isolated from the twig). The other category was naringenin- rich endophytes comprised isolates F1 and F2, which were isolated from the fruit, and isolates T1, T3, T5 and T6 isolated from the twig. Moreover, extracts accumulated gallic acid were devoid of naringenin and the opposite was true. This behavior was not detected in the host plant where these two compounds coexist and identified in all extracts.
{"title":"Phenolic composition and biological activity of endophytic fungi isolates inhabited Acacia nilotica","authors":"Elham A.M Kheir, Adil A Elhussein, Gihan O.M El hassan, S. Yagi","doi":"10.53365/nrfhh/162876","DOIUrl":"https://doi.org/10.53365/nrfhh/162876","url":null,"abstract":"This study aimed to screen the phenolic profile, antimicrobial and antiradical activities of endophytic fungi residing in the tissues of Acacia nilotica grown in Sudan. Isolates of endophytic fungi were isolated from fruit, leaf and twig. Methanolic extracts were prepared by maceration. Antimicrobial activity was determined by the disc diffusion method. Antiradical activity was evaluated by the 1, 1-diphenyl-2-picryl hydrazyl (DPPH) assay. Ten endophytic fungi were recovered from the twig (6), leaf (2) and fruit (2) of A. nilotica. Extracts revealed better antifungal activity, with isolates T3, L1 and F1 exerting the highest inhibition zones (20.6, 20 and 18.3 mm, respectively) against Aspergillus niger. Isolates T4 and T5 revealed the highest antiradical effect with IC50 values of 302 and 478 µg/mL respectively. Chemical analysis revealed that gallic acid and naringenin were the dominant compounds. Their pattern divided the endophytic fungi into two categories; gallic acid- rich endophytes including isolates L1 and L2 (isolated from the leaf) as well as isolates T4 and T2 (isolated from the twig). The other category was naringenin- rich endophytes comprised isolates F1 and F2, which were isolated from the fruit, and isolates T1, T3, T5 and T6 isolated from the twig. Moreover, extracts accumulated gallic acid were devoid of naringenin and the opposite was true. This behavior was not detected in the host plant where these two compounds coexist and identified in all extracts.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133716531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iron oxide nanoparticles (IONPs) have been widely used in environmental applications due to their low cost, safety, and effectiveness. This research successfully produced IONPs by hydrothermally reacting iron rust and Aloe vera gel plant extract at 100 oC for 18 hours in an autoclave cell. IONPs were produced to prevent detrimental effects on human health by degrading methylene blue dye (MB). IONPs were characterized by XRD, FE-SEM, and FT-IR spectroscopy. The small crystalline size (19 nm), and (inverse cubic) structure (magnetite) of (Fe3O4 NPs) 600 oC were explained by measurements of XRD, whereas small crystalline (Fe902O) NPs of 300 oC were of 28 nm. FESEM revealed that the particle size of (Fe3O4) NPs at 600 oC using an aloe vera extract was (26.80 to 37.96) nm, whereas Fe902O (wustite) at 300 oC was tiny and crystalline at (31.63 to 130.3) nm. The strong absorption band for Fe3O4 NPs (magnetites) at 600 °C with aloe vera is explained by the FT-IR spectra. The absorption peak was high at (650) cm-1 and corresponded to the Fe-O series of Fe902O NPs at 300 oC. When the spectra showed the absorption peak, it was strong. Iron oxide NPs have been used for a short time in environmental treatment to remove MB dye. For 40 minutes of IONPs (Fe3O4), the results of degradation effectiveness (95%) were 300 oC for MB dye, but degradation efficiency (91%) was 75 minutes of IONPs (Fe902O) with aloe vera at 600 oC for MB dye.
{"title":"Study the degradation and photocatalytic activity of the methylene blue dye by mixing the Aloe vera extract with rust iron oxide nanoparticle","authors":"D. A. Kadhim, M. Abid, W. Salih","doi":"10.53365/nrfhh/170025","DOIUrl":"https://doi.org/10.53365/nrfhh/170025","url":null,"abstract":"Iron oxide nanoparticles (IONPs) have been widely used in environmental applications due to their low cost, safety, and effectiveness. This research successfully produced IONPs by hydrothermally reacting iron rust and Aloe vera gel plant extract at 100 <sup>o</sup>C for 18 hours in an autoclave cell. IONPs were produced to prevent detrimental effects on human health by degrading methylene blue dye (MB). IONPs were characterized by XRD, FE-SEM, and FT-IR spectroscopy. The small crystalline size (19 nm), and (inverse cubic) structure (magnetite) of (Fe<sub>3</sub>O<sub>4</sub> NPs) 600 <sup>o</sup>C were explained by measurements of XRD, whereas small crystalline (Fe902O) NPs of 300 <sup>o</sup>C were of 28 nm. FESEM revealed that the particle size of (Fe<sub>3</sub>O<sub>4</sub>) NPs at 600 <sup>o</sup>C using an aloe vera extract was (26.80 to 37.96) nm, whereas Fe902O (wustite) at 300 <sup>o</sup>C was tiny and crystalline at (31.63 to 130.3) nm. The strong absorption band for Fe<sub>3</sub>O<sub>4</sub> NPs (magnetites) at 600 °C with aloe vera is explained by the FT-IR spectra. The absorption peak was high at (650) cm<sup>-1</sup> and corresponded to the Fe-O series of Fe902O NPs at 300 <sup>o</sup>C. When the spectra showed the absorption peak, it was strong. Iron oxide NPs have been used for a short time in environmental treatment to remove MB dye. For 40 minutes of IONPs (Fe<sub>3</sub>O<sub>4</sub>), the results of degradation effectiveness (95%) were 300 <sup>o</sup>C for MB dye, but degradation efficiency (91%) was 75 minutes of IONPs (Fe902O) with aloe vera at 600 <sup>o</sup>C for MB dye.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133592968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Razafimahatratra A. J. E, Robijaona Rahelivololoniaina B., Rakotojaona A. M. T., Ranjatoson N., Rabearisoa S.R., K. Ngbolua, Razafindrakoto F.N.R., Letsara R., Razafimahefa M.V.
Green MAE (microwave extraction) process was used to extract natural flavors (vanillin) from Madagascar Vanilla planifolia beans. Experimentally, we used a factor to study the influence of parameters on extraction efficiency, and response surface methodology (RSM) was used to obtain interactions between the key influencing parameters. The present study used response surface methodology (RSM) to optimize extraction parameters for vanillin compounds from Vanilla planifolia beans from Madagascar. Three independent variables were evaluated that had a major impact on vanillin content: alcohol concentration, microwave power, and solvent/material (S/M) ratio. A central composite rotation design (CCRD) was used to develop the experimental design. The optimal conditions for microwave-assisted extraction to obtain higher vanillin yield in pods are 480 W for microwave power, 72% for alcohol concentration, and 30 ml/g for Solvent/Material ratio, with an irradiation time of 60 min. The conventional Soxhlet method is less efficient than microwave extraction to extract vanillin from pods. In the traditional extraction, the optimal conditions were an extraction time of 16 hours for 90% ethanol as the solvent. The experimental values are close to those predicted by the obtained mathematical model. Vanilla extracts are analyzed by UV Visible spectrophotometry and HPLC.
{"title":"Microwave-assisted Extraction of Vanillin from Madagascar Vanilla planifolia beans: Optimization and Modeling","authors":"Razafimahatratra A. J. E, Robijaona Rahelivololoniaina B., Rakotojaona A. M. T., Ranjatoson N., Rabearisoa S.R., K. Ngbolua, Razafindrakoto F.N.R., Letsara R., Razafimahefa M.V.","doi":"10.53365/nrfhh/169229","DOIUrl":"https://doi.org/10.53365/nrfhh/169229","url":null,"abstract":"Green MAE (microwave extraction) process was used to extract natural flavors (vanillin) from Madagascar Vanilla planifolia beans. Experimentally, we used a factor to study the influence of parameters on extraction efficiency, and response surface methodology (RSM) was used to obtain interactions between the key influencing parameters. The present study used response surface methodology (RSM) to optimize extraction parameters for vanillin compounds from Vanilla planifolia beans from Madagascar. Three independent variables were evaluated that had a major impact on vanillin content: alcohol concentration, microwave power, and solvent/material (S/M) ratio. A central composite rotation design (CCRD) was used to develop the experimental design. The optimal conditions for microwave-assisted extraction to obtain higher vanillin yield in pods are 480 W for microwave power, 72% for alcohol concentration, and 30 ml/g for Solvent/Material ratio, with an irradiation time of 60 min. The conventional Soxhlet method is less efficient than microwave extraction to extract vanillin from pods. In the traditional extraction, the optimal conditions were an extraction time of 16 hours for 90% ethanol as the solvent. The experimental values are close to those predicted by the obtained mathematical model. Vanilla extracts are analyzed by UV Visible spectrophotometry and HPLC.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115123215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ayşe Ömerli, H. Ulger, M. Nisari, A. Yay, G. Karatoprak
The principal objective of this inquiry was to explore the potential impact of Viburnum opulus L. fruit juice in mitigating the occurrence of kidney stone formation within a rat model induced experimentally to develop kidney stones. Twenty Sprague Dawley rats were used in the study. They were placed in metabolic cages, with one rat per cage. Urine samples were collected every day during the study period. Biochemıcal values were measured in urine and blood. The rats were sacrificed, and their kidneys were removed and evaluated histopathologically after staining with Hematoxylin-Eosin (HE) and Pizzolato's (PZ) staining methods. The biochemical parameters observed in the urine samples collected from the experimental group of rats exhibited more excellent proximity to the negative control group's corresponding values than those of the positive control group. Upon microscopic examination of histological sections, a notable resemblance in histological architecture was discerned between the experimental and negative control groups. Additionally, a reduction in the incidence of stone formation was observed in the experimental group when contrasted with the positive control group. In light of the outcomes elucidated herein, it can be deduced that the administration of Viburnum opulus (VO) water engenders an augmenting impact on citrate levels. This elevation in citrate concentration holds potential significance as it demonstrates the potential to curtail crystal formation. Notably, citrate ions exhibit an inhibitory role in the genesis of calcium oxalate (CaOx) crystals, thereby contributing to the prevention.
{"title":"Could juice from Viburnum opulus potentially prevent the formation of kidney stones? (an anımal study)","authors":"Ayşe Ömerli, H. Ulger, M. Nisari, A. Yay, G. Karatoprak","doi":"10.53365/nrfhh/170923","DOIUrl":"https://doi.org/10.53365/nrfhh/170923","url":null,"abstract":"The principal objective of this inquiry was to explore the potential impact of Viburnum opulus L. fruit juice in mitigating the occurrence of kidney stone formation within a rat model induced experimentally to develop kidney stones. Twenty Sprague Dawley rats were used in the study. They were placed in metabolic cages, with one rat per cage. Urine samples were collected every day during the study period. Biochemıcal values were measured in urine and blood. The rats were sacrificed, and their kidneys were removed and evaluated histopathologically after staining with Hematoxylin-Eosin (HE) and Pizzolato's (PZ) staining methods. The biochemical parameters observed in the urine samples collected from the experimental group of rats exhibited more excellent proximity to the negative control group's corresponding values than those of the positive control group. Upon microscopic examination of histological sections, a notable resemblance in histological architecture was discerned between the experimental and negative control groups. Additionally, a reduction in the incidence of stone formation was observed in the experimental group when contrasted with the positive control group. In light of the outcomes elucidated herein, it can be deduced that the administration of Viburnum opulus (VO) water engenders an augmenting impact on citrate levels. This elevation in citrate concentration holds potential significance as it demonstrates the potential to curtail crystal formation. Notably, citrate ions exhibit an inhibitory role in the genesis of calcium oxalate (CaOx) crystals, thereby contributing to the prevention.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115594212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Subfertile males with idiopathic oligoasthenoteratozoospermia (iOAT) can experience a decrease in fertilization and conception rates. Natural antioxidant supplements and herbal treatments recognized to be effective in enhancing fertility. These have the potential to become one of the most efficient medications for treating male infertility. Our study emphasis at how these medication interventions improve several semen parameters while diminishing male factor infertility. A comprehensive literature search using PubMed, Embase, Scopus, Google Scholar and Science Direct were conducted to locate the research papers, focusing the usage of herbal and antioxidant therapies and their favourable effects on various semen parameters on reproductive health. Research based on in vitro and in vivo studies showed that antioxidants, herbal remedies and synthetic therapies have a substantial influence on various sperm parameter. The findings of randomized clinical trials and other preclinical data on exposure of numerous antioxidant supplements, herbal medicines and synthetic therapy demonstrated a considerable benefit to sperm parameters like sperm count, motility, morphology and fertilization rates. It is evident that herbal therapy and proper antioxidant supplementation can improve the rate of conception, so in contrary to synthetic medication, natural and antioxidant therapies are liable to provide better treatment options in managing male fecundity problems.
{"title":"Role of herbal, nutraceutical and synthetic agents in oligoasthenoteratozoospermia: A comparative assessment","authors":"N. John, Litty Joseph","doi":"10.53365/nrfhh/166370","DOIUrl":"https://doi.org/10.53365/nrfhh/166370","url":null,"abstract":"Subfertile males with idiopathic oligoasthenoteratozoospermia (iOAT) can experience a decrease in fertilization and conception rates. Natural antioxidant supplements and herbal treatments recognized to be effective in enhancing fertility. These have the potential to become one of the most efficient medications for treating male infertility. Our study emphasis at how these medication interventions improve several semen parameters while diminishing male factor infertility. A comprehensive literature search using PubMed, Embase, Scopus, Google Scholar and Science Direct were conducted to locate the research papers, focusing the usage of herbal and antioxidant therapies and their favourable effects on various semen parameters on reproductive health. Research based on in vitro and in vivo studies showed that antioxidants, herbal remedies and synthetic therapies have a substantial influence on various sperm parameter. The findings of randomized clinical trials and other preclinical data on exposure of numerous antioxidant supplements, herbal medicines and synthetic therapy demonstrated a considerable benefit to sperm parameters like sperm count, motility, morphology and fertilization rates. It is evident that herbal therapy and proper antioxidant supplementation can improve the rate of conception, so in contrary to synthetic medication, natural and antioxidant therapies are liable to provide better treatment options in managing male fecundity problems.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123836378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gaurav Kasar, Pooja Rasal, Manoj Mahajan, A. Upaganlawar, C. Upasani
Diabetic Neuropathy (DN) is major chronic consequences of the diabetes. DN is developed due to chronic hyperglycemia which is related with generation of oxidative stress (OS) and alteration in the neuronal function. This study was envisaged to find the desirable neuroprotective outcomes of natural antioxidants i.e., lycopene and coenzyme Q10 (CoQ10) as monotherapy or concomitant administration in rats subjected to DN induced by streptozotocin (STZ). Single subcutaneous dose of STZ (55 mg/kg) was used to induce DN in male wistar rats (200–250 g). Significant neuropathy was observed after four weeks of streptozotocin injection. Neuropathy was evaluated by behavioral parameters using mechanical allodynia, mechanical hyperalgesia, heat/thermal hyperalgesia and walking track analysis. Oxidative stress was determined by assessment of malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH), and nitric oxide (NO) in homogenate of sciatic nerve. STZ significantly alters all the behavioral as well as biochemical parameters. Treatment with lycopene (5mg/kg/p.o.), CoQ10 (10mg/kg, p.o.) and their combination for four weeks significantly reduced blood glucose level. The behavioural and biochemical alteration was significantly improved with the combination of lycopene and CoQ10. The combination of both the antioxidants significantly reversed the streptozotocin induced neuropathy in rats compared to alone antioxidants as well as diabetic neuropathy group. It is concluded that neuroprotective effect of lycopene, CoQ10 alone and in combination might be due to their strong antioxidant property.
{"title":"Effect of Lycopene alone and along with Coenzyme-Q10 in Streptozotocin Induced Peripheral Neuropathy: Biochemical & Behavioural Study","authors":"Gaurav Kasar, Pooja Rasal, Manoj Mahajan, A. Upaganlawar, C. Upasani","doi":"10.53365/nrfhh/163104","DOIUrl":"https://doi.org/10.53365/nrfhh/163104","url":null,"abstract":"Diabetic Neuropathy (DN) is major chronic consequences of the diabetes. DN is developed due to chronic hyperglycemia which is related with generation of oxidative stress (OS) and alteration in the neuronal function. This study was envisaged to find the desirable neuroprotective outcomes of natural antioxidants i.e., lycopene and coenzyme Q10 (CoQ10) as monotherapy or concomitant administration in rats subjected to DN induced by streptozotocin (STZ). Single subcutaneous dose of STZ (55 mg/kg) was used to induce DN in male wistar rats (200–250 g). Significant neuropathy was observed after four weeks of streptozotocin injection. Neuropathy was evaluated by behavioral parameters using mechanical allodynia, mechanical hyperalgesia, heat/thermal hyperalgesia and walking track analysis. Oxidative stress was determined by assessment of malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH), and nitric oxide (NO) in homogenate of sciatic nerve. STZ significantly alters all the behavioral as well as biochemical parameters. Treatment with lycopene (5mg/kg/p.o.), CoQ10 (10mg/kg, p.o.) and their combination for four weeks significantly reduced blood glucose level. The behavioural and biochemical alteration was significantly improved with the combination of lycopene and CoQ10. The combination of both the antioxidants significantly reversed the streptozotocin induced neuropathy in rats compared to alone antioxidants as well as diabetic neuropathy group. It is concluded that neuroprotective effect of lycopene, CoQ10 alone and in combination might be due to their strong antioxidant property.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"265 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133473396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The use of biological controllers of natural origin against pests of agricultural and health importance has been increasingly recommended in recent years due to lower environmental toxicity, in addition to promoting greater safety for human and animal health. At the same time, the development of studies with native and promising plant resources, which are still little studied, means that conservation measures for these species are encouraged. In this context, this review aims to optimize and discuss the use of essential oils from plants that grow in Carapebus sandbanks as controllers of Brazil's most important agricultural pests and disease transmitters. This work was presented as an important tool for promoting plant resources in the fight against these pests in Brazilian territory, aiming to stimulate more eco-friendly and safer-health agents in agronomic practices and for the urban and rural population use. Furthermore, these essential oils, in addition to presenting an interesting potential to be used as organic insecticides, also contribute to the valorization of native species.
{"title":"Essential oils from Carapebus sandbank plants as natural controllers against insect pests of importance in Brazilian public health and agriculture","authors":"R. D. de Albuquerque, L. Rocha","doi":"10.53365/nrfhh/161456","DOIUrl":"https://doi.org/10.53365/nrfhh/161456","url":null,"abstract":"The use of biological controllers of natural origin against pests of agricultural and health importance has been increasingly recommended in recent years due to lower environmental toxicity, in addition to promoting greater safety for human and animal health. At the same time, the development of studies with native and promising plant resources, which are still little studied, means that conservation measures for these species are encouraged. In this context, this review aims to optimize and discuss the use of essential oils from plants that grow in Carapebus sandbanks as controllers of Brazil's most important agricultural pests and disease transmitters. This work was presented as an important tool for promoting plant resources in the fight against these pests in Brazilian territory, aiming to stimulate more eco-friendly and safer-health agents in agronomic practices and for the urban and rural population use. Furthermore, these essential oils, in addition to presenting an interesting potential to be used as organic insecticides, also contribute to the valorization of native species.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126030785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pakeer Mohideen Askar Nawas, Seyed Mafiya Haniff, K. Sundararasu, T. Shankar, Sakthivel Venkatesh
Exopolysaccharide (EPS) samples were collected from the Mandapam camp, India. Morphological, biochemical characterization and 16S rRNA gene sequencing were done and the candidate bacterium was confirmed as Citrobacter sp. EPS production was observed from bacteria in Malt medium broth (0.88 ± 0.04mg/ml). The optimal cultural conditions for EPS production were as follows: after 72 hours of incubation at pH 8.0 (0.75 ± 0.1 mg/ml), the temperature at 40⁰C (0.75 ± 0.1 mg/ml), 100 rpm (0.90 ± 0.1 mg/ml). In the experimentation, arabinose (carbon sources) (1. ± 0.120 mg/ml) and ammonium nitrate (nitrogen) (1.30 ± 0.1 mg/ml) showed better results for the yield of EPS. The highest production of EPS was recorded in Triton X-100 (surfactants) supplemented medium. The optimal production of EPS was obtained in 2.5% sodium chloride added medium. Then the 2.5% inoculum concentration better for maximizing the yield of EPS. The best yield of EPS was noticed in after 96 hours of incubation time.
{"title":"Optimization of culture conditions for the production of exopolysaccharides from marine isolate Citrobacter sp.","authors":"Pakeer Mohideen Askar Nawas, Seyed Mafiya Haniff, K. Sundararasu, T. Shankar, Sakthivel Venkatesh","doi":"10.53365/nrfhh/159497","DOIUrl":"https://doi.org/10.53365/nrfhh/159497","url":null,"abstract":"Exopolysaccharide (EPS) samples were collected from the Mandapam camp, India. Morphological, biochemical characterization and 16S rRNA gene sequencing were done and the candidate bacterium was confirmed as Citrobacter sp. EPS production was observed from bacteria in Malt medium broth (0.88 ± 0.04mg/ml). The optimal cultural conditions for EPS production were as follows: after 72 hours of incubation at pH 8.0 (0.75 ± 0.1 mg/ml), the temperature at 40⁰C (0.75 ± 0.1 mg/ml), 100 rpm (0.90 ± 0.1 mg/ml). In the experimentation, arabinose (carbon sources) (1. ± 0.120 mg/ml) and ammonium nitrate (nitrogen) (1.30 ± 0.1 mg/ml) showed better results for the yield of EPS. The highest production of EPS was recorded in Triton X-100 (surfactants) supplemented medium. The optimal production of EPS was obtained in 2.5% sodium chloride added medium. Then the 2.5% inoculum concentration better for maximizing the yield of EPS. The best yield of EPS was noticed in after 96 hours of incubation time.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128906333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vycttor Mateus Silva, A. Silva, R. Cunha, J. Oliveira, Layza Fernanda Bezerra, Vera Lima
Introduction: Neotropical genus Ceiba Mill. is known for having tall trees, trunks with a robust part and fruits of economic interest. In Brazil, there are eleven native species, from those five are endemic. It is used in folk medicine to treat diabetes, inflammation, pain and diarrhea; however, most of the species have no scientific validation for such activities. This review aims to compile information about the genus Ceiba in Brazil, to update and allow an integrated understanding of its medicinal uses, chemical composition, and biological activities. Methodology: Ceiba species reported in Flora e Funga do Brasil were used for this literature review, using ScienceDirect, PubMed, and Google Scholar as articles databases. Results: In traditional use, the most cited species was C. pentandra (25 citations), the most used part was stem/bark (30 citations), preparation method was decoction (19 citations), and main administration route was oral ingestion (12 reports) for digestive system, skin and subcutaneous tissues diseases treatment. Genus chemical composition is wide, presenting metabolites such as proteins, sugars, fatty acids, tannins, flavonoids, and alkaloids. Bioactivities as antidiabetic, antioxidant, antitumor and antimicrobial were observed, especially for C. pentandra. Conclusion: Some species of Ceiba have extensive scientific literature, presenting several isolated compounds and bioactivities. On the other hand, some species, especially those that are endemics only in Brazil, do not have studies that evaluate their biological properties. Such knowledge is essential to confirm the medicinal potential cited in ethnobotanical reports, and the possibility of new compounds of biotechnological interest
简介:新热带属Ceiba Mill。以高大的树木、粗壮的树干和经济利益的果实而闻名。在巴西，有11种本地物种，其中5种是地方性的。民间医学中用于治疗糖尿病、炎症、疼痛和腹泻;然而，大多数物种对这种活动没有科学证实。这篇综述的目的是汇编有关巴西Ceiba属植物的信息，更新和允许对其药用、化学成分和生物活性有一个全面的了解。方法:本文献综述采用Flora e Funga do Brasil中报道的木棉物种，使用ScienceDirect、PubMed和Google Scholar作为文章数据库。结果:在传统用法中，被引种最多的是五角草(25篇)，部位最多的是茎/皮(30篇)，制备方法为煎煮(19篇)，主要给药途径为口服(12篇)，用于消化系统、皮肤及皮下组织疾病的治疗。属的化学成分很广泛，包括代谢产物，如蛋白质、糖、脂肪酸、单宁、类黄酮和生物碱。观察其抗糖尿病、抗氧化、抗肿瘤、抗菌等生物活性。结论:部分木棉属植物具有广泛的科学文献，具有一定的分离化合物和生物活性。另一方面，一些物种，特别是那些仅在巴西特有的物种，没有对其生物学特性进行评估的研究。这些知识对于确认民族植物学报告中引用的药物潜力以及生物技术兴趣的新化合物的可能性至关重要
{"title":"Genus Ceiba Mill. in Brazil: A comprehensive review on its ethnopharmacology, phytochemistry and bioactivities","authors":"Vycttor Mateus Silva, A. Silva, R. Cunha, J. Oliveira, Layza Fernanda Bezerra, Vera Lima","doi":"10.53365/nrfhh/160949","DOIUrl":"https://doi.org/10.53365/nrfhh/160949","url":null,"abstract":"Introduction: Neotropical genus Ceiba Mill. is known for having tall trees, trunks with a robust part and fruits of economic interest. In Brazil, there are eleven native species, from those five are endemic. It is used in folk medicine to treat diabetes, inflammation, pain and diarrhea; however, most of the species have no scientific validation for such activities. This review aims to compile information about the genus Ceiba in Brazil, to update and allow an integrated understanding of its medicinal uses, chemical composition, and biological activities. Methodology: Ceiba species reported in Flora e Funga do Brasil were used for this literature review, using ScienceDirect, PubMed, and Google Scholar as articles databases. Results: In traditional use, the most cited species was C. pentandra (25 citations), the most used part was stem/bark (30 citations), preparation method was decoction (19 citations), and main administration route was oral ingestion (12 reports) for digestive system, skin and subcutaneous tissues diseases treatment. Genus chemical composition is wide, presenting metabolites such as proteins, sugars, fatty acids, tannins, flavonoids, and alkaloids. Bioactivities as antidiabetic, antioxidant, antitumor and antimicrobial were observed, especially for C. pentandra. Conclusion: Some species of Ceiba have extensive scientific literature, presenting several isolated compounds and bioactivities. On the other hand, some species, especially those that are endemics only in Brazil, do not have studies that evaluate their biological properties. Such knowledge is essential to confirm the medicinal potential cited in ethnobotanical reports, and the possibility of new compounds of biotechnological interest","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134130733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sonia Molina-Romani, Pablo Bonilla-Rivera, R. D. de Albuquerque
Bixa orellana, known as Annato or Achiote, is a species popularly used in various countries of America as a dye and medicine. Its leaves possess several biological activities and are commonly marketed as filters. However, despite some ethnomedicinal and pharmacological studies with Bixa orellana leaves having been published, there is a lack of review articles that collect this information. In addition, the few studies about the quality parameters of these filters must be addressed jointly so that the usefulness of existing information can be better addressed in the discussion of commercial regulation. In this way, this review aims to compile systematically useful information about the medicinal use and pharmacology of B. orellana leaves, in addition to channeling the studies on the quality parameters of filters, which in turn can define the quality, efficacy and safety of the marketed products. As a result of the review, the searches showed that the leaves of B. orellana are traditionally used for various purposes, including treatment of headache, bronchitis, and inflammation, in addition to using as a diuretic, analgesic, antiophidic, among others. These findings were corroborated by pharmacological studies, which also point to other biological activities such as antioxidant, antimicrobial, anti-inflammatory, neurodepressant and gastrointestinal modulator through the administration of leaf extracts. Finally, stability and extraction yield studies were also important in providing data for implementing quality control of B. orellana products.
{"title":"A review of Bixa orellana L. (Annatto) leaves as medicinal resource: Use in the population as complementary medicine, phytotherapeutic action and quality parameters","authors":"Sonia Molina-Romani, Pablo Bonilla-Rivera, R. D. de Albuquerque","doi":"10.53365/nrfhh/161027","DOIUrl":"https://doi.org/10.53365/nrfhh/161027","url":null,"abstract":"Bixa orellana, known as Annato or Achiote, is a species popularly used in various countries of America as a dye and medicine. Its leaves possess several biological activities and are commonly marketed as filters. However, despite some ethnomedicinal and pharmacological studies with Bixa orellana leaves having been published, there is a lack of review articles that collect this information. In addition, the few studies about the quality parameters of these filters must be addressed jointly so that the usefulness of existing information can be better addressed in the discussion of commercial regulation. In this way, this review aims to compile systematically useful information about the medicinal use and pharmacology of B. orellana leaves, in addition to channeling the studies on the quality parameters of filters, which in turn can define the quality, efficacy and safety of the marketed products. As a result of the review, the searches showed that the leaves of B. orellana are traditionally used for various purposes, including treatment of headache, bronchitis, and inflammation, in addition to using as a diuretic, analgesic, antiophidic, among others. These findings were corroborated by pharmacological studies, which also point to other biological activities such as antioxidant, antimicrobial, anti-inflammatory, neurodepressant and gastrointestinal modulator through the administration of leaf extracts. Finally, stability and extraction yield studies were also important in providing data for implementing quality control of B. orellana products.","PeriodicalId":394827,"journal":{"name":"Natural Resources for Human Health","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124365578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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