Takayasu arteritis is a chronic inflammation involving large vessels and it often occurs in young women of childbearing age. We described a case of a 29- year- old lady with previous history of proliferative ischemic retinopathy was noted to have low upper limbs blood pressure and weak upper limb pulses postpartumly. An urgent CT angiogram of thorax revealed features suggestive of large vessel vasculitis with involvement of ascending arch, descending aorta and its main branches, corresponding to type II TA . She was diagnosed to have Takayasu arteritis post delivery, and she underwent a successful pregnancy without intrapartum and postpartum complications. High index of suspicion must be given for pregnant patient who have persistent low blood pressure and weak pulse for early detection to avoid severe complications.
{"title":"Undiagnosed Takayasu Arteritis in Pregnancy","authors":"Shi Qiu, Y. Cheng, L. Tan, W. S. Wan Ghazali","doi":"10.47836/mjmhs.19.3.49","DOIUrl":"https://doi.org/10.47836/mjmhs.19.3.49","url":null,"abstract":"Takayasu arteritis is a chronic inflammation involving large vessels and it often occurs in young women of childbearing age. We described a case of a 29- year- old lady with previous history of proliferative ischemic retinopathy was noted to have low upper limbs blood pressure and weak upper limb pulses postpartumly. An urgent CT angiogram of thorax revealed features suggestive of large vessel vasculitis with involvement of ascending arch, descending aorta and its main branches, corresponding to type II TA . She was diagnosed to have Takayasu arteritis post delivery, and she underwent a successful pregnancy without intrapartum and postpartum complications. High index of suspicion must be given for pregnant patient who have persistent low blood pressure and weak pulse for early detection to avoid severe complications.","PeriodicalId":40029,"journal":{"name":"Malaysian Journal of Medicine and Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48391554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Husna Ahmad Ainuddin, M. Romli, Mazatulfazura SF Salim, T. Hamid, L. Mackenzie
Introduction: A stroke can have devastating consequences and may reduce the Quality of Life (QoL) of stroke survivors. Specific QoL measurement is therefore needed to appreciate and quantify the impact of this condition. The objective of the study is to culturally adapt, translate and validate the Bahasa Melayu, Mandarin and Tamil versions of the Stroke Impact Scale (SIS) 3.0 for its application in clinical practice and stroke research in Malaysia. Methods: A total of nine translators translated the SIS 3.0 and five professional experts carried out the linguistic validation of the SIS 3.0 in accordance with the Mapi Research Institute’s linguistic validation guideline. The steps for linguistic validation included forward translation, synthesis, backward translation, clinicians’ review, and cognitive debriefing. Ten to thirteen healthcare practitioners rated the translated versions of SIS 3.0 using the Content Validity Index (CVI) and Content Validity Ratio (CVR). Results: During the translation processes, concerns were expressed about various grammatical and semantic issues, such as the appropriateness of some phrases used for the Malaysian demographic. The Scale-CVI average was 0.91 and 0.95 for relevance and clarity respectively which indicated excellent content validity. The CVR values ranged from 0.40 to 1.00. Conclusion: The Bahasa Melayu, Mandarin and Tamil versions of SIS 3.0 was well developed. The translated versions of SIS 3.0 could be adopted in clinical, community and educational settings. Nevertheless, further in-depth psychometric testing including construct validity and reliability on a larger sample among the multi-ethic Malaysians stroke survivors is advised.
{"title":"Linguistic and Content Validation of the Stroke Impact Scale (SIS) 3.0 in Three Languages","authors":"Husna Ahmad Ainuddin, M. Romli, Mazatulfazura SF Salim, T. Hamid, L. Mackenzie","doi":"10.47836/mjmhs.19.3.4","DOIUrl":"https://doi.org/10.47836/mjmhs.19.3.4","url":null,"abstract":"Introduction: A stroke can have devastating consequences and may reduce the Quality of Life (QoL) of stroke survivors. Specific QoL measurement is therefore needed to appreciate and quantify the impact of this condition. The objective of the study is to culturally adapt, translate and validate the Bahasa Melayu, Mandarin and Tamil versions of the Stroke Impact Scale (SIS) 3.0 for its application in clinical practice and stroke research in Malaysia. Methods: A total of nine translators translated the SIS 3.0 and five professional experts carried out the linguistic validation of the SIS 3.0 in accordance with the Mapi Research Institute’s linguistic validation guideline. The steps for linguistic validation included forward translation, synthesis, backward translation, clinicians’ review, and cognitive debriefing. Ten to thirteen healthcare practitioners rated the translated versions of SIS 3.0 using the Content Validity Index (CVI) and Content Validity Ratio (CVR). Results: During the translation processes, concerns were expressed about various grammatical and semantic issues, such as the appropriateness of some phrases used for the Malaysian demographic. The Scale-CVI average was 0.91 and 0.95 for relevance and clarity respectively which indicated excellent content validity. The CVR values ranged from 0.40 to 1.00. Conclusion: The Bahasa Melayu, Mandarin and Tamil versions of SIS 3.0 was well developed. The translated versions of SIS 3.0 could be adopted in clinical, community and educational settings. Nevertheless, further in-depth psychometric testing including construct validity and reliability on a larger sample among the multi-ethic Malaysians stroke survivors is advised.","PeriodicalId":40029,"journal":{"name":"Malaysian Journal of Medicine and Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41666477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nurul Atikah Annuar, K. John, Noor Jannah Yob, Y. Zakaria, S. N. Hussin
Introduction: Caffeine is a psychoactive substance widely consumed over the past decades. The effect of caffeine can be either beneficial or harmful. It increases cognitive performances, including attention, alertness and concentration. However, high caffeine intake may also induce an anxiogenic effect, causing symptoms such as rapid heart rate, restlessness and nervousness. This study aimed to determine the association between caffeine intake and mental health disorders such as anxiety and depression among undergraduate pharmacy students at UiTM Puncak Alam. Methods: This was a cross-sectional study with stratified random convenience sampling. A total of 270 undergraduate pharmacy students in UiTM Puncak Alam, Selangor participated in this study. A set of questionnaires was distributed using the Google Form platform. Standard General Anxiety Disorder (GAD-7) and Patient Health Questionnaire (PHQ-9) scoring were used to assess the level of anxiety and depression among the respondents, respectively. SPSS version 27.0 was used to analyse the data. Results: About 70.4% of the students consumed caffeine, while 29.6% of the students did not consume caffeine. No significant association was found between caffeine status and the mental health scoring of GAD-7 (χ2=4.639, p=0.200) and PHQ-9 (χ2=5.256, p=0.262). Conclusion: Non-daily consumption and a low dose of caffeine intake patterns are good practises to prevent the development of anxiety or depression conditions, although the associations were not significant. Public awareness on possible anxiogenic effect and mental related disorders due to caffeine consumption need to be initiated, as nowadays, the caffeine intake behaviour has become a trendy lifestyle among the young adults.
{"title":"Caffeine Intake and Its Association with Mental Health Status among Pharmacy Students at UiTM Puncak Alam","authors":"Nurul Atikah Annuar, K. John, Noor Jannah Yob, Y. Zakaria, S. N. Hussin","doi":"10.47836/mjmhs.19.3.6","DOIUrl":"https://doi.org/10.47836/mjmhs.19.3.6","url":null,"abstract":"Introduction: Caffeine is a psychoactive substance widely consumed over the past decades. The effect of caffeine can be either beneficial or harmful. It increases cognitive performances, including attention, alertness and concentration. However, high caffeine intake may also induce an anxiogenic effect, causing symptoms such as rapid heart rate, restlessness and nervousness. This study aimed to determine the association between caffeine intake and mental health disorders such as anxiety and depression among undergraduate pharmacy students at UiTM Puncak Alam. Methods: This was a cross-sectional study with stratified random convenience sampling. A total of 270 undergraduate pharmacy students in UiTM Puncak Alam, Selangor participated in this study. A set of questionnaires was distributed using the Google Form platform. Standard General Anxiety Disorder (GAD-7) and Patient Health Questionnaire (PHQ-9) scoring were used to assess the level of anxiety and depression among the respondents, respectively. SPSS version 27.0 was used to analyse the data. Results: About 70.4% of the students consumed caffeine, while 29.6% of the students did not consume caffeine. No significant association was found between caffeine status and the mental health scoring of GAD-7 (χ2=4.639, p=0.200) and PHQ-9 (χ2=5.256, p=0.262). Conclusion: Non-daily consumption and a low dose of caffeine intake patterns are good practises to prevent the development of anxiety or depression conditions, although the associations were not significant. Public awareness on possible anxiogenic effect and mental related disorders due to caffeine consumption need to be initiated, as nowadays, the caffeine intake behaviour has become a trendy lifestyle among the young adults.","PeriodicalId":40029,"journal":{"name":"Malaysian Journal of Medicine and Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41675101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Naini, Agus Sumono, R. Parnaadji, Nike Hendrijantini, Siti Khaerunnisa
Introduction: Tooth extraction before denture placement could result in trauma and damage to up to 50% of the alveolar bone, inducing bone resorption, and affecting the patient’s quality of life. Hydroxyapatite Gypsum Puger (HAGP) can be used as an alternative to bone graft material which degrades slowly, affecting the proliferation and activity of cells that are responsible for bone tissue engineering. This study aimed to analyze the regeneration mechanism of alveolar bone by administering the HAGP scaffold and observing the Stro-1, Runx-2, Osterix, and ALP expression. Methods: Laboratory experimental research was conducted and we used 150-355µm HAGP scaffold particles, applied in vivo inside alveolar sockets of the rats for 7, 14, and 28 days, followed by immunohistochemical examination of Stro-1, Runx-2, Osterix, and ALP expressions. Results: The HAGP scaffold group showed that the Stro-1 expression was significantly higher than the K(-) group, and the Runx-2 expression increased on day 7 and decreased on day 28 in the HAGP and K(-) groups. Osterix expression increased from day 7, 14, to day 28. The high expression of Osterix on day 28 means it took over the Runx-2 function. In ALP there was a significant increase on day 7. ALP expression was a sign of early osteoblast differentiation and production by cells, this extracellular matrix mineralization is an indicator of the osteogenic process. Conclusion: Alveolar bone regeneration mechanism in rats revealed that the expression of Stro-1, Runx-2, Osterix, and ALP was higher in the HAGP scaffold group compared to the control group on days 7,14, and 28.
{"title":"Expression of Stro-1, Runx-2, Osterix, and Alp in Alveolar Bone Regeneration Process Following the Administration of Hydroxyapatite Gypsum Puger (HAGP) Scaffold","authors":"A. Naini, Agus Sumono, R. Parnaadji, Nike Hendrijantini, Siti Khaerunnisa","doi":"10.47836/mjmhs.19.3.19","DOIUrl":"https://doi.org/10.47836/mjmhs.19.3.19","url":null,"abstract":"Introduction: Tooth extraction before denture placement could result in trauma and damage to up to 50% of the alveolar bone, inducing bone resorption, and affecting the patient’s quality of life. Hydroxyapatite Gypsum Puger (HAGP) can be used as an alternative to bone graft material which degrades slowly, affecting the proliferation and activity of cells that are responsible for bone tissue engineering. This study aimed to analyze the regeneration mechanism of alveolar bone by administering the HAGP scaffold and observing the Stro-1, Runx-2, Osterix, and ALP expression. Methods: Laboratory experimental research was conducted and we used 150-355µm HAGP scaffold particles, applied in vivo inside alveolar sockets of the rats for 7, 14, and 28 days, followed by immunohistochemical examination of Stro-1, Runx-2, Osterix, and ALP expressions. Results: The HAGP scaffold group showed that the Stro-1 expression was significantly higher than the K(-) group, and the Runx-2 expression increased on day 7 and decreased on day 28 in the HAGP and K(-) groups. Osterix expression increased from day 7, 14, to day 28. The high expression of Osterix on day 28 means it took over the Runx-2 function. In ALP there was a significant increase on day 7. ALP expression was a sign of early osteoblast differentiation and production by cells, this extracellular matrix mineralization is an indicator of the osteogenic process. Conclusion: Alveolar bone regeneration mechanism in rats revealed that the expression of Stro-1, Runx-2, Osterix, and ALP was higher in the HAGP scaffold group compared to the control group on days 7,14, and 28.","PeriodicalId":40029,"journal":{"name":"Malaysian Journal of Medicine and Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46578539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fathima Begum Syed Mohideen, Mohd. Radzniwan A. Rashid, Nur Faraheen Abdul Rahman, Muhammad Tauffik Mohd Noor, Sharifah Najwa Syed Mohamad
Introduction: The COVID-19 pandemic significantly impacted the global teaching and learning process (TnL). Unfortunately, to date, not many qualitative studies have been published specifically on the impact of COVID-19 on the Family Medicine course, particularly in Malaysia. Hence, this study aimed to explore the impact of COVID-19 pandemic on the teaching and learning experience of undergraduate students undergoing their Family Medicine course at a local university. Methods: A qualitative study using focused group discussion (FGD), was conducted among undergraduate students during the lockdown period. A semi-structured interview guide was used to interview 20 students, in their fifth undergraduate year, undertaking their fourth to fifth week of a total six-week course. They were selected using purposive snowball sampling method. There were four focus group discussions (FGD) with five students in a group. All interviews were audio-taped, transcribed verbatim, and the contents were analysed using the standard content analysis framework. Subsequently, thematic content analysis was conducted, and three major themes were produced. Results: The three major themes were (1) facilitators to learning, (2) barriers to learning, and (3) rooms for improvement. Conclusion: Although COVID-19 pandemic had significant impact on TnL of Family Medicine course among undergraduates, the students remained optimistic and proposed some improvement from their point of view. However, a creative, realistic, effective, and impactful way of TnL, particularly in clinical aspects should be developed and experimented. Technological progress and advancement should permit this idea to be achievable and implemented in near future.
{"title":"A Qualitative Study Exploring the Impact of Covid-19 Pandemic on Teaching and Learning of Family Medicine Course among Undergraduates in a Local University in Malaysia","authors":"Fathima Begum Syed Mohideen, Mohd. Radzniwan A. Rashid, Nur Faraheen Abdul Rahman, Muhammad Tauffik Mohd Noor, Sharifah Najwa Syed Mohamad","doi":"10.47836/mjmhs.19.3.15","DOIUrl":"https://doi.org/10.47836/mjmhs.19.3.15","url":null,"abstract":"Introduction: The COVID-19 pandemic significantly impacted the global teaching and learning process (TnL). Unfortunately, to date, not many qualitative studies have been published specifically on the impact of COVID-19 on the Family Medicine course, particularly in Malaysia. Hence, this study aimed to explore the impact of COVID-19 pandemic on the teaching and learning experience of undergraduate students undergoing their Family Medicine course at a local university. Methods: A qualitative study using focused group discussion (FGD), was conducted among undergraduate students during the lockdown period. A semi-structured interview guide was used to interview 20 students, in their fifth undergraduate year, undertaking their fourth to fifth week of a total six-week course. They were selected using purposive snowball sampling method. There were four focus group discussions (FGD) with five students in a group. All interviews were audio-taped, transcribed verbatim, and the contents were analysed using the standard content analysis framework. Subsequently, thematic content analysis was conducted, and three major themes were produced. Results: The three major themes were (1) facilitators to learning, (2) barriers to learning, and (3) rooms for improvement. Conclusion: Although COVID-19 pandemic had significant impact on TnL of Family Medicine course among undergraduates, the students remained optimistic and proposed some improvement from their point of view. However, a creative, realistic, effective, and impactful way of TnL, particularly in clinical aspects should be developed and experimented. Technological progress and advancement should permit this idea to be achievable and implemented in near future.","PeriodicalId":40029,"journal":{"name":"Malaysian Journal of Medicine and Health Sciences","volume":"220 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135140354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ai-Hong Chen, Nur Rifqah Roslan, YW Hoe Cosette, Swee Chai Teoh
Introduction: The COVID-19 pandemic has precipitated a rapid shift of learning and education from traditional means to digital platforms. This paper aims to examine the impact of online learning on digital engagement and digital-related health symptoms among university students one year into the coronavirus pandemic. Methods: Data was collected through a self-administered online questionnaire after ethical approval. The questionnaire was adapted from the previously published Lifestyle Study in Youth Questionnaire. Through the questionnaire, the perception of students toward online learning was probed and recorded. Digital engagement and digital-related health symptoms were compared before and during the COVID-19 lockdown. Results: The majority (97.5%) of respondents preferred face-to-face learning. The time spent on digital devices was 1.8 times higher during COVID-19 than before the COVID-19 lockdown (t-test = -18.86, p<0.0001). The total hours of sleep were reduced during COVID-19 lockdown (0.6 hours lesser) (t-test = -3.92, p<0.0001). The Wilcoxon Signed Ranks Test revealed significant changes in digital-related health symptoms (15 out of 17) due to the COVID-19 lockdown. Digital eye strain, dry eye syndrome, carpal tunnel syndrome, and upper quadrant postural and muscle strain emerged (p<0.05). Conclusion: Most university students favoured face-to-face learning compared to online learning. There was a two-fold rise in digital engagement during the COVID-19 lockdown. As a result, it has seemed to translate into reduced sleeping hours. The short-term impact of the coronavirus pandemic on digital-related health symptoms amongst university students was apparent. The long-term effects require further investigations to facilitate fact-based decision-making.
{"title":"Online Learning and Its Short-term Impact on Digital Engagement and Digital-related Health Symptoms Amongst University Students During the COVID-19 Pandemic","authors":"Ai-Hong Chen, Nur Rifqah Roslan, YW Hoe Cosette, Swee Chai Teoh","doi":"10.47836/mjmhs.19.3.18","DOIUrl":"https://doi.org/10.47836/mjmhs.19.3.18","url":null,"abstract":"Introduction: The COVID-19 pandemic has precipitated a rapid shift of learning and education from traditional means to digital platforms. This paper aims to examine the impact of online learning on digital engagement and digital-related health symptoms among university students one year into the coronavirus pandemic. Methods: Data was collected through a self-administered online questionnaire after ethical approval. The questionnaire was adapted from the previously published Lifestyle Study in Youth Questionnaire. Through the questionnaire, the perception of students toward online learning was probed and recorded. Digital engagement and digital-related health symptoms were compared before and during the COVID-19 lockdown. Results: The majority (97.5%) of respondents preferred face-to-face learning. The time spent on digital devices was 1.8 times higher during COVID-19 than before the COVID-19 lockdown (t-test = -18.86, p<0.0001). The total hours of sleep were reduced during COVID-19 lockdown (0.6 hours lesser) (t-test = -3.92, p<0.0001). The Wilcoxon Signed Ranks Test revealed significant changes in digital-related health symptoms (15 out of 17) due to the COVID-19 lockdown. Digital eye strain, dry eye syndrome, carpal tunnel syndrome, and upper quadrant postural and muscle strain emerged (p<0.05). Conclusion: Most university students favoured face-to-face learning compared to online learning. There was a two-fold rise in digital engagement during the COVID-19 lockdown. As a result, it has seemed to translate into reduced sleeping hours. The short-term impact of the coronavirus pandemic on digital-related health symptoms amongst university students was apparent. The long-term effects require further investigations to facilitate fact-based decision-making.","PeriodicalId":40029,"journal":{"name":"Malaysian Journal of Medicine and Health Sciences","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135140355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noor Hayati Sabtu, F. Idris, Eusni Rahayu Tohit, A. Abu Bakar, Wan Aswani Wan Yusof, R. Osman
In systemic lupus erythematosus (SLE), haematological abnormalities are frequent, although they are an uncommon cause of acquired von Willebrand syndrome (AVWS). AVWS is a rare condition that can cause a bleeding disorder. We presented a case of AVWS in the early diagnosis of SLE. One month before admission, the patient had a history of recurrent epistaxis. He presented to the hospital with symptomatic anaemia and was noted to have severe anaemia with iron deficiency. During hospitalisation, recurrent epistaxis recurred and was found to have prolonged activated partial thromboplastin time (aPTT), presence of lupus anticoagulant (LA), and lower von Willebrand factor (VWF), and factor 8 (VIII) levels. Simultaneously, he was diagnosed with SLE based on Systemic Lupus International Collaborating Clinics (SLICC) criteria. He underwent blood transfusions and was treated with immunosuppressive drugs such as steroids, mycophenolate mofetil, and an anti-fibrinolytic agent; he subsequently stopped bleeding and showed clinical improvement.
{"title":"A Teenage Boy with Systemic Lupus Erythematosus Complicated with Acquired von Willebrand Syndrome: A Rare Case and Challenging in Making Diagnosis","authors":"Noor Hayati Sabtu, F. Idris, Eusni Rahayu Tohit, A. Abu Bakar, Wan Aswani Wan Yusof, R. Osman","doi":"10.47836/mjmhs.19.3.50","DOIUrl":"https://doi.org/10.47836/mjmhs.19.3.50","url":null,"abstract":"In systemic lupus erythematosus (SLE), haematological abnormalities are frequent, although they are an uncommon cause of acquired von Willebrand syndrome (AVWS). AVWS is a rare condition that can cause a bleeding disorder. We presented a case of AVWS in the early diagnosis of SLE. One month before admission, the patient had a history of recurrent epistaxis. He presented to the hospital with symptomatic anaemia and was noted to have severe anaemia with iron deficiency. During hospitalisation, recurrent epistaxis recurred and was found to have prolonged activated partial thromboplastin time (aPTT), presence of lupus anticoagulant (LA), and lower von Willebrand factor (VWF), and factor 8 (VIII) levels. Simultaneously, he was diagnosed with SLE based on Systemic Lupus International Collaborating Clinics (SLICC) criteria. He underwent blood transfusions and was treated with immunosuppressive drugs such as steroids, mycophenolate mofetil, and an anti-fibrinolytic agent; he subsequently stopped bleeding and showed clinical improvement.","PeriodicalId":40029,"journal":{"name":"Malaysian Journal of Medicine and Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46142435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Metabolic syndrome has become a worry for health of youth in Malaysia. This study aimed to look at the prevalence of metabolic syndrome, and to assess the risk factors of metabolic syndrome among Malaysian university students. Methods: A cross-sectional study was conducted on 248 students aged 18-30 years using a random sampling method from two universities in Bintulu, Sarawak, Malaysia. Data on sociodemographic, dietary habits and lifestyle were collected by a pre-tested self-reported questionnaire. Biochemical measurements, blood pressure, and anthropometric measurements were measured by standard procedures. Metabolic syndrome was defined according to Harmonized Joint Interim Statement criteria. Data were analysed using IBM SPSS 23.0 version. Results: The overall prevalence of metabolic syndrome was 12.5% and was more prevalent in male (17.5%). Indian (15.8%) was the most prevalent ethnic group, while Chinese (4.9%) had the least prevalence. 31.5% respondents had at least one metabolic component. Low HDL (42.7%) and large waist circumference (26.2%) were the most common components. Statistically significant (p<0.05) independent factors for developing metabolic syndrome were male, staying time more than six hours on computer/TV/mobile phone, in smokers, taking meals more than three times per day, and high consumption of soft drinks. Besides that, with high consumption of vegetables, the prevalence of metabolic syndrome was significantly low (p<0.05). Conclusion: These study findings elicit the evidence of increasing tendency and warning on metabolic syndrome for Malaysian university students, and considerable association of the prevalence of metabolic syndrome to dietary habits and lifestyle.
{"title":"Prevalence and Risk Factors Associated with Metabolic Syndrome among University Students in Bintulu, Sarawak, Malaysia","authors":"Sharifa Sadia Mahmud, Tunung Robin, Shahrul Razid Sarbini","doi":"10.47836/mjmhs.19.3.10","DOIUrl":"https://doi.org/10.47836/mjmhs.19.3.10","url":null,"abstract":"Introduction: Metabolic syndrome has become a worry for health of youth in Malaysia. This study aimed to look at the prevalence of metabolic syndrome, and to assess the risk factors of metabolic syndrome among Malaysian university students. Methods: A cross-sectional study was conducted on 248 students aged 18-30 years using a random sampling method from two universities in Bintulu, Sarawak, Malaysia. Data on sociodemographic, dietary habits and lifestyle were collected by a pre-tested self-reported questionnaire. Biochemical measurements, blood pressure, and anthropometric measurements were measured by standard procedures. Metabolic syndrome was defined according to Harmonized Joint Interim Statement criteria. Data were analysed using IBM SPSS 23.0 version. Results: The overall prevalence of metabolic syndrome was 12.5% and was more prevalent in male (17.5%). Indian (15.8%) was the most prevalent ethnic group, while Chinese (4.9%) had the least prevalence. 31.5% respondents had at least one metabolic component. Low HDL (42.7%) and large waist circumference (26.2%) were the most common components. Statistically significant (p<0.05) independent factors for developing metabolic syndrome were male, staying time more than six hours on computer/TV/mobile phone, in smokers, taking meals more than three times per day, and high consumption of soft drinks. Besides that, with high consumption of vegetables, the prevalence of metabolic syndrome was significantly low (p<0.05). Conclusion: These study findings elicit the evidence of increasing tendency and warning on metabolic syndrome for Malaysian university students, and considerable association of the prevalence of metabolic syndrome to dietary habits and lifestyle.","PeriodicalId":40029,"journal":{"name":"Malaysian Journal of Medicine and Health Sciences","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135140352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: This study aims to provide the current situation of leprosy prevalence and clinical findings in one of the endemic regions of North Gresik City that has already achieved elimination status. Leprosy remains a public health problem in some developing countries, including Indonesia. Indonesia, with two other big countries, India and Brazil, contributed 74% of all the new leprosy cases detected. Even though Indonesia achieved the elimination target from WHO in 2018, the endemic pockets are still scattered, and new cases remain detected each year. Methods: This study is a one-decade retrospective analysis descriptive record based on newly diagnosed cases of leprosy from 2010 until 2020. We use total data sampling of all newly diagnosed leprosy cases and analyze using SPSS. Result: This study found that newly diagnosed cases of leprosy are still discovered each year. 15.7% of newly diagnosed cases were children. MB type was dominated type in this study. MB types are statistically significant in male subjects (35.5%) diagnosed more than one year after the symptoms appear. 40.7% were found with deformity when first diagnosed. Conclusion: This study reports a high rate of contracting leprosy disease in children, with 15.7% of cases. It indicates that disease transmission remains high in the community and might be out of control. The new cases diagnosed dominated with MB type, and 40.7% had deformity when first diagnosed. There was a delayed diagnosis reported that could be caused by ineffective surveillance for early diagnosing new cases.
{"title":"Current Status of Leprosy in the Rural Area of North Gresik, Indonesia After Eliminated Status Achieved: “Is Leprosy Truly Eliminated?”","authors":"Hapsari Kinanti, M. Alinda","doi":"10.47836/mjmhs.19.3.35","DOIUrl":"https://doi.org/10.47836/mjmhs.19.3.35","url":null,"abstract":"Introduction: This study aims to provide the current situation of leprosy prevalence and clinical findings in one of the endemic regions of North Gresik City that has already achieved elimination status. Leprosy remains a public health problem in some developing countries, including Indonesia. Indonesia, with two other big countries, India and Brazil, contributed 74% of all the new leprosy cases detected. Even though Indonesia achieved the elimination target from WHO in 2018, the endemic pockets are still scattered, and new cases remain detected each year. Methods: This study is a one-decade retrospective analysis descriptive record based on newly diagnosed cases of leprosy from 2010 until 2020. We use total data sampling of all newly diagnosed leprosy cases and analyze using SPSS. Result: This study found that newly diagnosed cases of leprosy are still discovered each year. 15.7% of newly diagnosed cases were children. MB type was dominated type in this study. MB types are statistically significant in male subjects (35.5%) diagnosed more than one year after the symptoms appear. 40.7% were found with deformity when first diagnosed. Conclusion: This study reports a high rate of contracting leprosy disease in children, with 15.7% of cases. It indicates that disease transmission remains high in the community and might be out of control. The new cases diagnosed dominated with MB type, and 40.7% had deformity when first diagnosed. There was a delayed diagnosis reported that could be caused by ineffective surveillance for early diagnosing new cases.","PeriodicalId":40029,"journal":{"name":"Malaysian Journal of Medicine and Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44496043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Agriculture is one of Malaysia’s most important contributions, estimated to improve GDP by 4.3% by 2030 (1). In Malaysia, rice is one of the most frequently farmed crops, in addition to oil palm and rubber, with annual consumption per person averaging 73.9 kilograms (2). Commercial pesticides have thus been widely utilized in agriculture to meet this need since they are readily available, easy to use, and effective. Pesticides are also utilized to manage diseases and pests that constitute a major threat to agricultural output.
{"title":"Exposures of Pesticides and Health Impact on the Agricultural (Paddy) Community in Malaysia","authors":"Y. Ho","doi":"10.47836/mjmhs.19.3.1","DOIUrl":"https://doi.org/10.47836/mjmhs.19.3.1","url":null,"abstract":"Agriculture is one of Malaysia’s most important contributions, estimated to improve GDP by 4.3% by 2030 (1). In Malaysia, rice is one of the most frequently farmed crops, in addition to oil palm and rubber, with annual consumption per person averaging 73.9 kilograms (2). Commercial pesticides have thus been widely utilized in agriculture to meet this need since they are readily available, easy to use, and effective. Pesticides are also utilized to manage diseases and pests that constitute a major threat to agricultural output.","PeriodicalId":40029,"journal":{"name":"Malaysian Journal of Medicine and Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49253395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：