首页 > 最新文献

Journal of Health and Allied Sciences NU最新文献

英文 中文
Association of Selected Fitness Variables with Perceived Performance Levels in Lawn Tennis Players 草地网球运动员选择的体能变量与感知表现水平的关联
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-03-17 DOI: 10.1055/s-0042-1760438
Sukriti Manchanda, S. Saxena, Pooja Sharma, M. Rizvi, Ankita Sharma, Irshad Ahmad, S. Kachanathu
Abstract Objectives  Lawn tennis is an explosive sport that involves various fitness parameters such as explosive strength, endurance, power, and agility. Improved physical fitness leads to superior athletic performance. The coach's perception is contingent upon his perception of the player at the time the athlete is comparing himself to the coach. Thus, this study aimed to determine the association between chosen fitness factors and perceived performance by coach in lawn tennis players. Thus, the study aims to detect the relationship between different fitness variables and perceived level of performance in lawn tennis player. Materials and Methods  Fifty-two lawn tennis players from two sports academies were measured for various parameters of fitness and perceived performance level as rated by the coach. Statistical Analysis  The association between selected fitness metrics and perceived performance in lawn tennis players was investigated using Pearson's correlation test. Furthermore, the data were analyzed with paired t -test for male and female group, and ANOVA was used to analyze the difference between the levels of performance. Results  Fatigue index, closed kinetic chain upper extremity stability (CKCUEST) test, and peak power and energy expenditure taken by metabolic equivalent (MET) calculation was found to be statistically different between males and females. While comparing BMI with the peak power, there was a weak positive correlation for males, while for female there was no correlation. Metabolic equivalent, energy expenditure, and peak power were positively correlated with the level of performance; however, fatigue index and level of performance had a negative nonsignificant correlation. Conclusion  Peak power, fatigue index, energy expenditure, and BMI were found to be associated in males, but not in females. Peak power and energy expenditure were connected to performance in both genders.
抽象目标 草地网球是一项具有爆发力的运动,涉及各种健身参数,如爆发力、耐力、力量和灵活性。身体素质的提高会带来卓越的运动表现。当运动员将自己与教练进行比较时,教练的看法取决于他对球员的看法。因此,本研究旨在确定草坪网球运动员所选择的健身因素与教练感知的表现之间的关系。因此,本研究旨在检测草坪网球运动员不同适应度变量与表现感知水平之间的关系。材料和方法 来自两所体育学院的52名草地网球运动员被测量了教练评定的各种体能参数和感知表现水平。统计分析 使用Pearson相关检验对草坪网球运动员的选定健身指标与感知表现之间的关系进行了调查。此外,采用配对t检验对男女组的数据进行分析,并使用方差分析来分析表现水平之间的差异。后果 疲劳指数、闭合动力链上肢稳定性(CKCUEST)测试以及通过代谢当量(MET)计算得出的峰值功率和能量消耗在男性和女性之间存在统计学差异。当将BMI和峰值功率进行比较时,男性的正相关较弱,而女性则没有相关。代谢当量、能量消耗和峰值功率与表现水平呈正相关;疲劳指数与工作表现水平呈负相关,但不显著。结论 峰值功率、疲劳指数、能量消耗和BMI在男性中被发现相关,但在女性中没有。峰值功率和能量消耗与两性的表现有关。
{"title":"Association of Selected Fitness Variables with Perceived Performance Levels in Lawn Tennis Players","authors":"Sukriti Manchanda, S. Saxena, Pooja Sharma, M. Rizvi, Ankita Sharma, Irshad Ahmad, S. Kachanathu","doi":"10.1055/s-0042-1760438","DOIUrl":"https://doi.org/10.1055/s-0042-1760438","url":null,"abstract":"Abstract Objectives  Lawn tennis is an explosive sport that involves various fitness parameters such as explosive strength, endurance, power, and agility. Improved physical fitness leads to superior athletic performance. The coach's perception is contingent upon his perception of the player at the time the athlete is comparing himself to the coach. Thus, this study aimed to determine the association between chosen fitness factors and perceived performance by coach in lawn tennis players. Thus, the study aims to detect the relationship between different fitness variables and perceived level of performance in lawn tennis player. Materials and Methods  Fifty-two lawn tennis players from two sports academies were measured for various parameters of fitness and perceived performance level as rated by the coach. Statistical Analysis  The association between selected fitness metrics and perceived performance in lawn tennis players was investigated using Pearson's correlation test. Furthermore, the data were analyzed with paired t -test for male and female group, and ANOVA was used to analyze the difference between the levels of performance. Results  Fatigue index, closed kinetic chain upper extremity stability (CKCUEST) test, and peak power and energy expenditure taken by metabolic equivalent (MET) calculation was found to be statistically different between males and females. While comparing BMI with the peak power, there was a weak positive correlation for males, while for female there was no correlation. Metabolic equivalent, energy expenditure, and peak power were positively correlated with the level of performance; however, fatigue index and level of performance had a negative nonsignificant correlation. Conclusion  Peak power, fatigue index, energy expenditure, and BMI were found to be associated in males, but not in females. Peak power and energy expenditure were connected to performance in both genders.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":"13 1","pages":"535 - 542"},"PeriodicalIF":0.3,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48098173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Socioeconomic Risk Factors for Preterm Birth in Manipur, Northeast India: A Community-Based Study 印度东北部曼尼普尔早产的社会经济风险因素:一项基于社区的研究
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-03-17 DOI: 10.1055/s-0043-1761609
Th Chitralekha Devi, H. S. Singh
Abstract Background  Preterm birth (PTB) is one of the world's leading health concerns, affecting both the mother and the children. This study was undertaken to determine the prevalence and socioeconomic factors associated with PTB among the Meitei women of Manipur. Materials and Methods  A community-based cross-sectional study was conducted in postpartum Meitei women of Manipur. Participants were 126 postpartum women that gave birth to a singleton live-born infant and were classified as women giving birth before 37 weeks of gestation (PTB) and women giving birth at ≥37 weeks (term). Data were compared using univariate analysis, and the association of socioeconomic factors with PTB was determined through multivariate logistic regression using Statistical Package for Social Sciences 25 version software program, and statistical significance was taken at a p -value < 0.05. Results The overall prevalence of PTB is 23.01%, of which 13.79% are of extremely preterm. This study revealed a significant association of PTB with mother's occupation (adjusted odds ratio [AOR] = 4.46, 95% confidence interval [CI]: 1.40–14.26, p  = 0.012), tobacco consumption during pregnancy (AOR = 2.90, 95% CI: 1.01–8.33, p  = 0.048), having family history of PTB (AOR = 3.14, 95% CI: 1.09–9.04, p  = 0.034), and early age at menarche (AOR = 4.26, 95% CI: 1.49–12.12, p  = 0.007). Conclusion  The study highlights the high prevalence of PTB and its association with various socioeconomic factors. Such community-specific studies should be performed to understand the differential risk factors of PTB to control premature death in under 5 years children and to promote women's reproductive health.
摘要背景 早产(PTB)是世界上主要的健康问题之一,影响母亲和孩子。本研究旨在确定曼尼普尔Meitei妇女PTB的患病率和相关的社会经济因素。材料和方法 一项基于社区的横断面研究是在曼尼普尔的梅泰产后妇女中进行的。参与者是126名产下单胎活产婴儿的产后妇女,分为妊娠37周(PTB)前分娩的妇女和≥37周(足月)分娩的妇女。使用单变量分析对数据进行比较,并使用社会科学统计软件包25版软件程序通过多变量逻辑回归确定社会经济因素与PTB的相关性,并以p值取统计学显著性 < 结果PTB总患病率为23.01%,其中极早产占13.79%。这项研究揭示了PTB与母亲职业的显著关联(调整后的比值比[AOR] = 4.46,95%置信区间[CI]:1.40–14.26,p = 0.012),孕期吸烟量(AOR = 2.90,95%置信区间:1.01–8.33,p = 0.048),具有PTB家族史(AOR = 3.14,95%置信区间:1.09–9.04,p = 0.034)和初潮早期(AOR = 4.26,95%置信区间:1.49–12.12,p = 0.007)。结论 该研究强调了PTB的高患病率及其与各种社会经济因素的关系。应进行此类针对社区的研究,以了解PTB的不同风险因素,从而控制5岁以下儿童的过早死亡,并促进妇女的生殖健康。
{"title":"Socioeconomic Risk Factors for Preterm Birth in Manipur, Northeast India: A Community-Based Study","authors":"Th Chitralekha Devi, H. S. Singh","doi":"10.1055/s-0043-1761609","DOIUrl":"https://doi.org/10.1055/s-0043-1761609","url":null,"abstract":"Abstract Background  Preterm birth (PTB) is one of the world's leading health concerns, affecting both the mother and the children. This study was undertaken to determine the prevalence and socioeconomic factors associated with PTB among the Meitei women of Manipur. Materials and Methods  A community-based cross-sectional study was conducted in postpartum Meitei women of Manipur. Participants were 126 postpartum women that gave birth to a singleton live-born infant and were classified as women giving birth before 37 weeks of gestation (PTB) and women giving birth at ≥37 weeks (term). Data were compared using univariate analysis, and the association of socioeconomic factors with PTB was determined through multivariate logistic regression using Statistical Package for Social Sciences 25 version software program, and statistical significance was taken at a p -value < 0.05. Results The overall prevalence of PTB is 23.01%, of which 13.79% are of extremely preterm. This study revealed a significant association of PTB with mother's occupation (adjusted odds ratio [AOR] = 4.46, 95% confidence interval [CI]: 1.40–14.26, p  = 0.012), tobacco consumption during pregnancy (AOR = 2.90, 95% CI: 1.01–8.33, p  = 0.048), having family history of PTB (AOR = 3.14, 95% CI: 1.09–9.04, p  = 0.034), and early age at menarche (AOR = 4.26, 95% CI: 1.49–12.12, p  = 0.007). Conclusion  The study highlights the high prevalence of PTB and its association with various socioeconomic factors. Such community-specific studies should be performed to understand the differential risk factors of PTB to control premature death in under 5 years children and to promote women's reproductive health.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":"13 1","pages":"568 - 574"},"PeriodicalIF":0.3,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43443404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Misidentification of Plasmodium Species by Cross-Reacting Primers and Cerebral Malaria Caused by Plasmodium vivax 交叉反应引物误认疟原虫种类与间日疟原虫所致脑型疟疾
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-03-17 DOI: 10.1055/s-0043-1761258
A. Rai, D. Pinto, P. Rai, S. Teerthanath, I. Karunasagar, R. Adiga
Abstract Introduction  The clinical presentation of a case as cerebral malaria with molecular identification confirming it as Plasmodium vivax underlines the importance of using molecular tools to identify the species and type of malaria. The possibility of the relationship between the complication observed during clinical diagnosis and the multifactorial molecular changes could likely be the reason for terming it cerebral malaria. Methods  We report four cases analyzed using the quantitative buffy coat technique followed by classical Giemsa stained thick-film microscopy, and nested polymerase chain reaction for the genus-specific region of Plasmodium targeting 18S rDNA followed by species-specific identification with a different set of primers and products confirmation with sequencing. Results  Primers targeting P. knowlesi generated the expected product size of 153 base pairs that, upon sequencing, matched with the P. vivax sequence reflecting the relatedness of the species. Likewise, primers targeting P. ovale generated a 456 product whose sequence matched the P. vivax sequence. Conclusion  Infection with P. vivax can potentially cause cerebral malaria, and P. vivax can cause severe malaria complications alone or mixed with other species and can show cerebral malaria signs, which are typically associated with P. falciparum infections. The sequence relatedness reflects the genome similarity between P. knowlesi and P. ovale with P. vivax . The need to reconfirm with an additional set of newly reported primers is mandatory.
摘要介绍1例脑型疟疾病例的临床表现,经分子鉴定证实为间日疟原虫,强调了利用分子工具鉴定疟疾种类和类型的重要性。临床诊断时观察到的并发症与多因素分子变化之间的关系可能是将其称为脑型疟疾的原因。方法对4例病例进行分析,首先采用定量黄膜技术,然后采用经典Giemsa染色厚膜显微镜,对疟原虫18S rDNA的属特异性区域进行巢式聚合酶链反应,然后用不同的引物进行种特异性鉴定,并对产物进行测序确认。结果以诺氏疟原虫为目标的引物产生了153个碱基对的预期产物,经测序,与间日疟原虫序列匹配,反映了该物种的亲缘性。同样,以卵形疟原虫为目标的引物产生了456个序列与间日疟原虫序列匹配的产物。结论间日疟原虫感染可引起脑型疟疾,间日疟原虫可单独或与其他疟原虫混合引起严重的疟疾并发症,并可出现脑型疟疾体征,这些体征通常与恶性疟原虫感染相关。序列亲缘性反映了诺氏疟原虫和卵形疟原虫与间日疟原虫的基因组相似性。必须用另一组新报告的引物重新确认。
{"title":"Misidentification of Plasmodium Species by Cross-Reacting Primers and Cerebral Malaria Caused by Plasmodium vivax","authors":"A. Rai, D. Pinto, P. Rai, S. Teerthanath, I. Karunasagar, R. Adiga","doi":"10.1055/s-0043-1761258","DOIUrl":"https://doi.org/10.1055/s-0043-1761258","url":null,"abstract":"Abstract Introduction  The clinical presentation of a case as cerebral malaria with molecular identification confirming it as Plasmodium vivax underlines the importance of using molecular tools to identify the species and type of malaria. The possibility of the relationship between the complication observed during clinical diagnosis and the multifactorial molecular changes could likely be the reason for terming it cerebral malaria. Methods  We report four cases analyzed using the quantitative buffy coat technique followed by classical Giemsa stained thick-film microscopy, and nested polymerase chain reaction for the genus-specific region of Plasmodium targeting 18S rDNA followed by species-specific identification with a different set of primers and products confirmation with sequencing. Results  Primers targeting P. knowlesi generated the expected product size of 153 base pairs that, upon sequencing, matched with the P. vivax sequence reflecting the relatedness of the species. Likewise, primers targeting P. ovale generated a 456 product whose sequence matched the P. vivax sequence. Conclusion  Infection with P. vivax can potentially cause cerebral malaria, and P. vivax can cause severe malaria complications alone or mixed with other species and can show cerebral malaria signs, which are typically associated with P. falciparum infections. The sequence relatedness reflects the genome similarity between P. knowlesi and P. ovale with P. vivax . The need to reconfirm with an additional set of newly reported primers is mandatory.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":"13 1","pages":"563 - 567"},"PeriodicalIF":0.3,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47557802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Planned Early Ambulation on Postoperative Recovery among Cesarean Mothers: A Quasi-experimental study in Mangaluru 计划早期下床对剖宫产母亲术后恢复的有效性:一项在曼格鲁的准实验研究
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-03-16 DOI: 10.1055/s-0043-1761212
Carol Karishma Alphones, Janet Prima Miranda
Abstract Background  Mothers with cesarean section need more attention and care. Early ambulation is the essential to restore the maximum muscle function and improve the health during postoperative period. Early ambulation certainly has proven to be effective in preventing postoperative complications. Aim  To evaluate the effectiveness of early ambulation on postoperative recovery among cesarean mothers. Methods  Nonprobability purposive sampling technique was used to select 60 cesarean mothers, with 30 samples in each of the experimental and control group. Mothers in the intervention group received bed exercises by the investigator such as flexion and extension of the extremities, upper limb exercises, lower limb exercise, turning the patient, sitting with dangling the feet, and deep breathing exercises which was initiated at 10 hours of cesarean section followed by standing and walking at 12 hours of cesarean section for twice a day, whereas the control group received routine treatment as per the hospital protocol. Demographic proforma was used to assess the demographic characteristics, and structured postoperative recovery assessment tool was used to assess four major components such as pain, breast feeding, postnatal changes, and activity of daily living. The obtained data were analyzed using descriptive and inferential statistics. Statistical Analysis  Significant difference in the postoperative recovery score was calculated by using RM-ANOVA and independent t -test and the association of postoperative recovery score with selected demographic variables done by chi-square test. Results The majority of mothers in intervention (66.7%) and control group (63.3%) were 24 to 29 years old and had secondary education (60% each). There was significant difference in breast feeding ( p  = 0.001), involution of uterus ( p  = 0.047), amount of lochia ( p  = 0.027), and activity of daily living in the intervention group ( p  < 0.05) compared with the control group. Conclusion  Early ambulation improves the postoperative recovery and helps to achieve a good sense of well-being.
背景剖宫产产妇需要更多的关注和护理。术后早期活动是恢复肌肉最大功能和改善健康的必要条件。早期活动当然已被证明对预防术后并发症有效。目的探讨早期下床对剖宫产产妇术后恢复的影响。方法采用非概率目的抽样方法,抽取剖宫产产妇60例,实验组和对照组各30例。干预组母亲在剖宫产10小时开始进行床上运动,包括四肢屈伸运动、上肢运动、下肢运动、翻身、悬空坐、深呼吸运动,剖宫产12小时开始站立、行走,每天2次,对照组按照医院方案进行常规治疗。采用人口统计学形式评估人口统计学特征,采用结构化术后恢复评估工具评估疼痛、母乳喂养、产后变化和日常生活活动等四个主要组成部分。所得数据采用描述性统计和推理统计进行分析。术后恢复评分采用RM-ANOVA和独立t检验计算差异有统计学意义,术后恢复评分与所选人口学变量的相关性采用卡方检验。结果干预组母亲以24 ~ 29岁为主(66.7%),对照组以中等文化程度为主(63.3%)。干预组在母乳喂养(p = 0.001)、子宫复旧(p = 0.047)、恶露量(p = 0.027)、日常生活活动(p < 0.05)等方面与对照组比较差异均有统计学意义。结论早期活动有助于术后恢复,获得良好的幸福感。
{"title":"Effectiveness of Planned Early Ambulation on Postoperative Recovery among Cesarean Mothers: A Quasi-experimental study in Mangaluru","authors":"Carol Karishma Alphones, Janet Prima Miranda","doi":"10.1055/s-0043-1761212","DOIUrl":"https://doi.org/10.1055/s-0043-1761212","url":null,"abstract":"Abstract Background  Mothers with cesarean section need more attention and care. Early ambulation is the essential to restore the maximum muscle function and improve the health during postoperative period. Early ambulation certainly has proven to be effective in preventing postoperative complications. Aim  To evaluate the effectiveness of early ambulation on postoperative recovery among cesarean mothers. Methods  Nonprobability purposive sampling technique was used to select 60 cesarean mothers, with 30 samples in each of the experimental and control group. Mothers in the intervention group received bed exercises by the investigator such as flexion and extension of the extremities, upper limb exercises, lower limb exercise, turning the patient, sitting with dangling the feet, and deep breathing exercises which was initiated at 10 hours of cesarean section followed by standing and walking at 12 hours of cesarean section for twice a day, whereas the control group received routine treatment as per the hospital protocol. Demographic proforma was used to assess the demographic characteristics, and structured postoperative recovery assessment tool was used to assess four major components such as pain, breast feeding, postnatal changes, and activity of daily living. The obtained data were analyzed using descriptive and inferential statistics. Statistical Analysis  Significant difference in the postoperative recovery score was calculated by using RM-ANOVA and independent t -test and the association of postoperative recovery score with selected demographic variables done by chi-square test. Results The majority of mothers in intervention (66.7%) and control group (63.3%) were 24 to 29 years old and had secondary education (60% each). There was significant difference in breast feeding ( p  = 0.001), involution of uterus ( p  = 0.047), amount of lochia ( p  = 0.027), and activity of daily living in the intervention group ( p  < 0.05) compared with the control group. Conclusion  Early ambulation improves the postoperative recovery and helps to achieve a good sense of well-being.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":"13 1","pages":"551 - 556"},"PeriodicalIF":0.3,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47585980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sarcomatoid Squamous Cell Carcinoma of Vocal Cord: An Uncommon Malignancy 声带肉瘤样鳞状细胞癌:一种罕见的恶性肿瘤
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-03-16 DOI: 10.1055/s-0042-1760440
Raveena Prasad, V. Bhat, Rajeshwary Aroor, Kishan Prasad Hosapatna Laxminarayana
Abstract Sarcomatoid squamous cell carcinoma is a rare variant of laryngeal carcinoma, which comprises 1.3% of all laryngeal malignancies. It is mainly seen in elderly individuals, with smoking and alcohol being common risk factors. The tumor is most common on true vocal cords; hence, patients especially present with dysphonia. We present a case of an elderly male patient who presented with dysphonia due to a vocal cord lesion. During microlaryngoscopy, a firm, exophytic lesion with a narrow stalk was attached to the anterior one-third of the right vocal cord, excised, and sent for histopathology. Histopathology was suggestive of sarcomatoid squamous cell carcinoma. The patient was successfully treated with radiotherapy. We conclude that benign-appearing laryngeal lesions need to be evaluated and histopathological examination to be performed so that rare entities such as sarcomatoid carcinoma, which mimics benign lesions, can be managed appropriately.
摘要肉瘤样鳞状细胞癌是一种罕见的喉癌变体,占喉部所有恶性肿瘤的1.3%。主要见于老年人,吸烟和饮酒是常见的危险因素。肿瘤最常见于真声带;因此,患者尤其表现为语音障碍。我们提出了一个病例的老年男性患者谁提出了语音障碍,由于声带病变。在喉镜检查中,我们发现右声带前三分之一处有一个坚硬的外生性病变,其茎部狭窄,切除后送去组织病理学检查。组织病理学提示为肉瘤样鳞状细胞癌。病人接受放射治疗成功。我们的结论是,良性的喉部病变需要进行评估和组织病理学检查,以便罕见的实体,如肉瘤样癌,模仿良性病变,可以得到适当的处理。
{"title":"Sarcomatoid Squamous Cell Carcinoma of Vocal Cord: An Uncommon Malignancy","authors":"Raveena Prasad, V. Bhat, Rajeshwary Aroor, Kishan Prasad Hosapatna Laxminarayana","doi":"10.1055/s-0042-1760440","DOIUrl":"https://doi.org/10.1055/s-0042-1760440","url":null,"abstract":"Abstract Sarcomatoid squamous cell carcinoma is a rare variant of laryngeal carcinoma, which comprises 1.3% of all laryngeal malignancies. It is mainly seen in elderly individuals, with smoking and alcohol being common risk factors. The tumor is most common on true vocal cords; hence, patients especially present with dysphonia. We present a case of an elderly male patient who presented with dysphonia due to a vocal cord lesion. During microlaryngoscopy, a firm, exophytic lesion with a narrow stalk was attached to the anterior one-third of the right vocal cord, excised, and sent for histopathology. Histopathology was suggestive of sarcomatoid squamous cell carcinoma. The patient was successfully treated with radiotherapy. We conclude that benign-appearing laryngeal lesions need to be evaluated and histopathological examination to be performed so that rare entities such as sarcomatoid carcinoma, which mimics benign lesions, can be managed appropriately.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":"13 1","pages":"587 - 590"},"PeriodicalIF":0.3,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46123931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protective Role of Hsp27 in the Nonylphenol-Induced Locomotory and Longevity Toxicity Hsp27在壬基酚运动和长寿毒性中的保护作用
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-03-16 DOI: 10.1055/s-0043-1761213
S. Dwivedi, Kean Anthony Daniel Francis, Anurag Sharma
Abstract Background  Gut health is directly proportional to an organism's fitness. Our recent study showed a functional link between oxidative stress and heat shock protein 27 (Hsp27, a stress protein) in the Drosophila larval gut, which coordinates the nonylphenol (an endocrine disruptor) allied sub-cellular and developmental adversities. Objective  In continuation with the prior study, the present study aimed to explore the association of Hsp27 with locomotory and survival against nonylphenol-induced toxicity in the Drosophila gut. Methods and Methodology  The freshly emerged adult flies were exposed to nonylphenol (5.0 µg/mL) for 10 to 40 days, and their locomotory performance (climbing activity) and survivability were assessed. ANOVA was used to evaluate the statistical significance of the mean values in control and treated flies. Results  Nonylphenol exposure markedly influenced locomotory activity and survivability after 30 to 40 days. For instance, ∼76% (40 days) declined locomotor behavior, and ∼35% (40 days) reduced survivability was observed. While the overexpression of Hsp27 in the organism's gut showed improvement in locomotory performance and survivability after 30 to 40 days. No significant alteration in locomotory performance and survivability was observed after 10 to 20 days of nonylphenol exposure. Conclusion  The present study illustrates that Hsp27 overexpression in the Drosophila gut improves the locomotory performance and survivability in the nonylphenol exposed Drosophila . This also indicates the possible connection between the gut and organismal fitness.
摘要背景 肠道健康与生物体的健康状况成正比。我们最近的研究表明,氧化应激和果蝇幼虫肠道中的热休克蛋白27(Hsp27,一种应激蛋白)之间存在功能联系,后者协调壬基酚(一种内分泌干扰物)相关的亚细胞和发育逆境。客观的 在先前研究的基础上,本研究旨在探讨Hsp27与果蝇肠道中壬基酚诱导毒性的运动能力和存活率的关系。方法和方法 将新出现的成年苍蝇暴露于壬基酚(5.0µg/mL)中10至40天,并评估它们的运动性能(攀爬活动)和生存能力。方差分析用于评估对照和处理苍蝇的平均值的统计学意义。后果 壬基酚暴露在30至40天后显著影响运动活性和生存能力。例如,观察到约76%(40天)的运动行为下降,约35%(40天则)的生存能力下降。而Hsp27在生物体肠道中的过表达在30至40天后显示出运动性能和生存能力的改善。壬基酚暴露10至20天后,未观察到运动性能和生存能力的显著变化。结论 本研究表明,Hsp27在果蝇肠道中的过表达改善了暴露于壬基酚的果蝇的运动性能和生存能力。这也表明了肠道和生物体健康之间可能存在的联系。
{"title":"Protective Role of Hsp27 in the Nonylphenol-Induced Locomotory and Longevity Toxicity","authors":"S. Dwivedi, Kean Anthony Daniel Francis, Anurag Sharma","doi":"10.1055/s-0043-1761213","DOIUrl":"https://doi.org/10.1055/s-0043-1761213","url":null,"abstract":"Abstract Background  Gut health is directly proportional to an organism's fitness. Our recent study showed a functional link between oxidative stress and heat shock protein 27 (Hsp27, a stress protein) in the Drosophila larval gut, which coordinates the nonylphenol (an endocrine disruptor) allied sub-cellular and developmental adversities. Objective  In continuation with the prior study, the present study aimed to explore the association of Hsp27 with locomotory and survival against nonylphenol-induced toxicity in the Drosophila gut. Methods and Methodology  The freshly emerged adult flies were exposed to nonylphenol (5.0 µg/mL) for 10 to 40 days, and their locomotory performance (climbing activity) and survivability were assessed. ANOVA was used to evaluate the statistical significance of the mean values in control and treated flies. Results  Nonylphenol exposure markedly influenced locomotory activity and survivability after 30 to 40 days. For instance, ∼76% (40 days) declined locomotor behavior, and ∼35% (40 days) reduced survivability was observed. While the overexpression of Hsp27 in the organism's gut showed improvement in locomotory performance and survivability after 30 to 40 days. No significant alteration in locomotory performance and survivability was observed after 10 to 20 days of nonylphenol exposure. Conclusion  The present study illustrates that Hsp27 overexpression in the Drosophila gut improves the locomotory performance and survivability in the nonylphenol exposed Drosophila . This also indicates the possible connection between the gut and organismal fitness.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":"13 1","pages":"557 - 562"},"PeriodicalIF":0.3,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43391005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and Validation of Nocturia-Related Quality of Life Assessment Scale among Adults 成人夜尿症相关生活质量评定量表的编制与验证
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-01-29 DOI: 10.1055/s-0042-1749378
Susamma Varughese, T. Rajeev, Devina E. Rodrigues, Suresh Sucharitha
Abstract Background  Nocturia has high impact on quality of life (QoL) based on varying geographical and cultural factors. Speculating this, nocturia-related QoL (NRQoL) assessment scale was developed precisely, appropriate to the Indian context. Objective  The current study aimed to develop and validate an NRQoL assessment scale for Indian adults. Methods  An exploratory descriptive design was performed among 420 cases and 206 controls aged 35 to 65 years from two selected tertiary hospitals in Mangaluru, Karnataka, India. The NRQoL assessment scale was formulated through the following phases: review of literature, evaluation by experts, and pretesting. Exploratory factor analysis (EFA) was performed to reduce the number of items and to define domains. Reliability, construct validity, discriminant validity, and convergent validity of the scale were calculated. Results  EFA resulted in the removal of seven items from a 36-item instrument, resulting NRQoL assessment scale into six domains as follows: (1) functional, (2) sleep, (3) emotional, (4) physical, (5) social and family, and (6) spiritual. The findings from the tertiary hospitals study confirmed that the scale was valid and reliable to measure NRQoL among adults. Conclusion  The NRQoL assessment scale is a new, valid, and reliable instrument that is well-understood by adults and can be answered quickly. It is a useful new tool that can be translated and tested in other cultures and languages.
夜尿症对生活质量(QoL)有很大的影响,这取决于不同的地理和文化因素。据此,夜尿相关生活质量(NRQoL)评估量表被精确地开发出来,适合印度的情况。目的编制并验证一套适用于印度成年人的NRQoL量表。方法对印度卡纳塔克邦曼格鲁鲁市两所三级医院35 ~ 65岁的420例患者和206例对照者进行探索性描述设计。NRQoL量表的制定经过文献查阅、专家评估、前测三个阶段。探索性因子分析(EFA)用于减少项目数量和定义领域。计算量表的信度、结构效度、判别效度和收敛效度。结果EFA从36个项目的量表中删除了7个项目,使NRQoL评估量表分为六个领域:(1)功能,(2)睡眠,(3)情绪,(4)身体,(5)社会和家庭,(6)精神。三级医院的研究结果证实了该量表测量成人NRQoL的有效性和可靠性。结论NRQoL量表是一种新的、有效的、可靠的量表,易于成人理解和快速回答。它是一种有用的新工具,可以在其他文化和语言中进行翻译和测试。
{"title":"Development and Validation of Nocturia-Related Quality of Life Assessment Scale among Adults","authors":"Susamma Varughese, T. Rajeev, Devina E. Rodrigues, Suresh Sucharitha","doi":"10.1055/s-0042-1749378","DOIUrl":"https://doi.org/10.1055/s-0042-1749378","url":null,"abstract":"Abstract Background  Nocturia has high impact on quality of life (QoL) based on varying geographical and cultural factors. Speculating this, nocturia-related QoL (NRQoL) assessment scale was developed precisely, appropriate to the Indian context. Objective  The current study aimed to develop and validate an NRQoL assessment scale for Indian adults. Methods  An exploratory descriptive design was performed among 420 cases and 206 controls aged 35 to 65 years from two selected tertiary hospitals in Mangaluru, Karnataka, India. The NRQoL assessment scale was formulated through the following phases: review of literature, evaluation by experts, and pretesting. Exploratory factor analysis (EFA) was performed to reduce the number of items and to define domains. Reliability, construct validity, discriminant validity, and convergent validity of the scale were calculated. Results  EFA resulted in the removal of seven items from a 36-item instrument, resulting NRQoL assessment scale into six domains as follows: (1) functional, (2) sleep, (3) emotional, (4) physical, (5) social and family, and (6) spiritual. The findings from the tertiary hospitals study confirmed that the scale was valid and reliable to measure NRQoL among adults. Conclusion  The NRQoL assessment scale is a new, valid, and reliable instrument that is well-understood by adults and can be answered quickly. It is a useful new tool that can be translated and tested in other cultures and languages.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":"13 1","pages":"469 - 478"},"PeriodicalIF":0.3,"publicationDate":"2023-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47213421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postoperative Discomfort Among Laparotomy Patients from a Selected Hospital at Mangaluru: An Observational Study Mangaluru某医院剖腹手术患者术后不适:一项观察性研究
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-01-24 DOI: 10.1055/s-0042-1760234
S. Latha, Neetha Kamath, Gincy Joseph
Abstract Background Factors causing postoperative discomfort after laparotomy are numerous and must be explored in depth. The postoperative distress may significantly affect the patient's state of well-being. Hence, the present study aims to assess the factors contributing to discomfort after laparotomy. Aim  The aim was to assess and compare the discomfort between open and laparoscopic abdominal surgery. Objectives of the Study 1. To analyze the causes of patient's discomfort after abdominal surgery. 2. To compare the discomfort between open and laparoscopic abdominal surgery. 3. To determine the association between pain and selected variables among open and laparoscopic abdominal surgery. Materials and Methods An exploratory approach with a prospective observational design was adopted for this study. Using the purposive sampling technique, 100 patients were selected to open and 100 to laparoscopic abdominal surgery groups. Data were collected using demographic and clinical proforma and standardized postoperative discomfort inventory 6 and 24 hours after the surgery. The assessment focused on the study variables such as symptoms after the surgery and the factors contributing to the postoperative discomfort. Statistical Analysis The collected data were analyzed using descriptive and inferential statistics using the SPSS software version 20. Results Among 200 participants, most of the open (68%) and laparoscopic abdominal surgeries (42%) belong to 25 to 35 years of age. Also, 54% and 13% were diabetic in open and laparoscopic abdominal surgery groups, respectively. Most samples (56% in open and 68% in laparoscopic surgery) stayed 5 and 10 hours in postoperative ICU. In open and laparoscopic abdominal surgeries, pain is the primary (100%) cause of postoperative discomfort after 6 hours of surgery. Movement restriction is also the reason for significant discomfort both in open (98%) and laparoscopic (100%) abdominal surgeries. In contrast, pain (99% and 100%), movement restriction (92% and 95%), and abdominal distention (61% and 34%) were the major problems contributing to the patient's discomfort after 24 hours of both open and laparoscopic surgeries too. There was a significant difference in causes of patient discomfort between open and laparoscopic abdominal surgery after 6 hours ( P <  0.05), except for discomfort related to IV drip ( P  = 0.852), constipation ( P =  0.2), and chills ( P =  0.6). Conclusion Even though pain is the major distressing factor both in open and laparoscopic surgeries, the current study highlights a few other factors that affect postoperative recovery. Nurses' attention to such distressing factors will fasten patients' recovery and quality of life after abdominal surgery.
背景剖腹手术后引起术后不适的因素很多,需要深入探讨。术后痛苦会显著影响患者的健康状态。因此,本研究旨在评估导致剖腹手术后不适的因素。目的评估和比较开放和腹腔镜腹部手术的不适感。研究目的:分析腹部手术后患者不适的原因。2. 比较开放腹部手术与腹腔镜腹部手术的不适感。3.目的:确定开放和腹腔镜腹部手术中疼痛与选定变量之间的关系。材料与方法本研究采用前瞻性观察设计的探索性方法。采用目的抽样法,选取开腹手术组100例,腹腔腹腔镜手术组100例。术后6和24小时采用人口统计学、临床形式和标准化术后不适调查表收集数据。评估的重点是研究变量,如术后症状和导致术后不适的因素。采用SPSS软件第20版对收集到的数据进行描述性统计和推断性统计。结果200例患者中,接受开放式腹部手术(68%)和腹腔镜腹部手术(42%)的患者年龄在25 ~ 35岁之间。此外,在开放和腹腔镜腹部手术组中,分别有54%和13%的患者患有糖尿病。大多数样本(56%为开放手术,68%为腹腔镜手术)术后在ICU住院5小时和10小时。在开放和腹腔镜腹部手术中,疼痛是术后6小时后术后不适的主要原因(100%)。活动受限也是开放式(98%)和腹腔镜(100%)腹部手术明显不适的原因。相比之下,疼痛(99%和100%)、运动受限(92%和95%)和腹胀(61%和34%)是导致患者在开放和腹腔镜手术24小时后不适的主要问题。除静脉滴注(P = 0.852)、便秘(P = 0.2)、寒战(P = 0.6)引起的不适外,开放腹部手术与腹腔镜腹部手术6小时后患者不适的原因差异有统计学意义(P < 0.05)。尽管疼痛是开放和腹腔镜手术的主要困扰因素,但目前的研究强调了影响术后恢复的其他一些因素。护士对这些困扰因素的重视,将加快患者腹部手术后的恢复和生活质量。
{"title":"Postoperative Discomfort Among Laparotomy Patients from a Selected Hospital at Mangaluru: An Observational Study","authors":"S. Latha, Neetha Kamath, Gincy Joseph","doi":"10.1055/s-0042-1760234","DOIUrl":"https://doi.org/10.1055/s-0042-1760234","url":null,"abstract":"Abstract Background Factors causing postoperative discomfort after laparotomy are numerous and must be explored in depth. The postoperative distress may significantly affect the patient's state of well-being. Hence, the present study aims to assess the factors contributing to discomfort after laparotomy. Aim  The aim was to assess and compare the discomfort between open and laparoscopic abdominal surgery. Objectives of the Study 1. To analyze the causes of patient's discomfort after abdominal surgery. 2. To compare the discomfort between open and laparoscopic abdominal surgery. 3. To determine the association between pain and selected variables among open and laparoscopic abdominal surgery. Materials and Methods An exploratory approach with a prospective observational design was adopted for this study. Using the purposive sampling technique, 100 patients were selected to open and 100 to laparoscopic abdominal surgery groups. Data were collected using demographic and clinical proforma and standardized postoperative discomfort inventory 6 and 24 hours after the surgery. The assessment focused on the study variables such as symptoms after the surgery and the factors contributing to the postoperative discomfort. Statistical Analysis The collected data were analyzed using descriptive and inferential statistics using the SPSS software version 20. Results Among 200 participants, most of the open (68%) and laparoscopic abdominal surgeries (42%) belong to 25 to 35 years of age. Also, 54% and 13% were diabetic in open and laparoscopic abdominal surgery groups, respectively. Most samples (56% in open and 68% in laparoscopic surgery) stayed 5 and 10 hours in postoperative ICU. In open and laparoscopic abdominal surgeries, pain is the primary (100%) cause of postoperative discomfort after 6 hours of surgery. Movement restriction is also the reason for significant discomfort both in open (98%) and laparoscopic (100%) abdominal surgeries. In contrast, pain (99% and 100%), movement restriction (92% and 95%), and abdominal distention (61% and 34%) were the major problems contributing to the patient's discomfort after 24 hours of both open and laparoscopic surgeries too. There was a significant difference in causes of patient discomfort between open and laparoscopic abdominal surgery after 6 hours ( P <  0.05), except for discomfort related to IV drip ( P  = 0.852), constipation ( P =  0.2), and chills ( P =  0.6). Conclusion Even though pain is the major distressing factor both in open and laparoscopic surgeries, the current study highlights a few other factors that affect postoperative recovery. Nurses' attention to such distressing factors will fasten patients' recovery and quality of life after abdominal surgery.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":"13 1","pages":"509 - 517"},"PeriodicalIF":0.3,"publicationDate":"2023-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46392595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Geospatial Distribution of Fluoride and Iron in Natural Water Sources in Mangalore City 芒格洛尔市天然水源氟、铁的地理空间分布
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-01-24 DOI: 10.1055/s-0042-1760322
Sharanya Kushalan, Anusha Kashyap, Shaiesh Morajkar, S. Hegde
Abstract Water is the most essential substance that supports life on earth. Animals and plants require water for their survival. Since water is being lost or used by our body, it is essential to replace it constantly. Humans need clean, potable water for consumption and to meet their daily hygiene needs. However, increased anthropogenic activities have caused a drastic increase in heavy metals in fresh waters. Heavy metals interfere with the normal physiology of the human body. It binds to cellular components, leading to dysfunction of the metabolic processes in our body. This study was undertaken to study the geospatial distribution of selected heavy metals in open-well waters within Mangalore City Corporation limits. Mangalore is perched strategically on the path of rapid development, heading toward becoming a smart city in India. Water samples were collected from all 60 wards in the jurisdiction of Mangalore City Corporation. The fluoride concentration was estimated using the spectrophotometric method using the Sodium 2-(parasulfophenylazo)-1,8-dihydroxy3,6-naphthalene disulfonate (SPADNS) reagent. Similarly, iron was estimated using the phenanthroline reagent. The findings report that the pH of the samples was acidic in 20 wards. Panambur, Kunjathbail North, Mannagudda, Court and Cantonment water was colored. Kunjathbail (North), Kunjathbail (South), Kambala, Kadri North, Bendoor, Bolar, Mannagudda, and Markada, showed high turbidity levels. The fluoride concentration in the samples collected from 60 wards of Mangalore city was less than 1.5 ppm, which is the permissible limit by the World Health Organization. Iron is within the permissible limit except for the wards Court and Boloor, which showed an iron concentration of 0.4 ppm and 3.08 ppm, respectively. However, arsenic was not detected in any of the 180 samples collected from the 60 wards of Mangalore City Corporation.
摘要水是支持地球上生命的最基本的物质。动物和植物需要水来生存。由于我们的身体正在流失或使用水,因此不断补充水是至关重要的。人类需要清洁的饮用水来消费,并满足日常卫生需求。然而,人类活动的增加导致淡水中重金属的急剧增加。重金属干扰人体的正常生理机能。它与细胞成分结合,导致我们身体代谢过程的功能障碍。本研究旨在研究芒格洛尔市公司范围内开放式井水中选定重金属的地理空间分布。芒格洛尔在战略上处于快速发展的道路上,正朝着成为印度智能城市的方向发展。从芒格洛尔市公司管辖范围内的所有60个病房采集了水样。使用2-(对磺苯基偶氮)-1,8-二羟基3,6-萘二磺酸钠(SPADNS)试剂的分光光度法估算氟化物浓度。类似地,使用菲咯啉试剂估算铁。调查结果显示,20个病房的样本pH值呈酸性。Panambur、Kunjathbail North、Mannagudda、Court和Cantonment的水都是彩色的。Kunjathbail(北部)、Kunjath bail(南部)、Kambala、Kadri北部、Bendoor、Bolar、Mannagudda和Markada的浊度水平较高。从芒格洛尔市60个病房采集的样本中的氟化物浓度低于1.5 ppm,这是世界卫生组织允许的限度。铁在允许范围内,但Court和Boloor区除外,其铁浓度为0.4 ppm和3.08 ppm。然而,在芒格洛尔市公司60个病房采集的180个样本中,任何一个都没有检测到砷。
{"title":"Geospatial Distribution of Fluoride and Iron in Natural Water Sources in Mangalore City","authors":"Sharanya Kushalan, Anusha Kashyap, Shaiesh Morajkar, S. Hegde","doi":"10.1055/s-0042-1760322","DOIUrl":"https://doi.org/10.1055/s-0042-1760322","url":null,"abstract":"Abstract Water is the most essential substance that supports life on earth. Animals and plants require water for their survival. Since water is being lost or used by our body, it is essential to replace it constantly. Humans need clean, potable water for consumption and to meet their daily hygiene needs. However, increased anthropogenic activities have caused a drastic increase in heavy metals in fresh waters. Heavy metals interfere with the normal physiology of the human body. It binds to cellular components, leading to dysfunction of the metabolic processes in our body. This study was undertaken to study the geospatial distribution of selected heavy metals in open-well waters within Mangalore City Corporation limits. Mangalore is perched strategically on the path of rapid development, heading toward becoming a smart city in India. Water samples were collected from all 60 wards in the jurisdiction of Mangalore City Corporation. The fluoride concentration was estimated using the spectrophotometric method using the Sodium 2-(parasulfophenylazo)-1,8-dihydroxy3,6-naphthalene disulfonate (SPADNS) reagent. Similarly, iron was estimated using the phenanthroline reagent. The findings report that the pH of the samples was acidic in 20 wards. Panambur, Kunjathbail North, Mannagudda, Court and Cantonment water was colored. Kunjathbail (North), Kunjathbail (South), Kambala, Kadri North, Bendoor, Bolar, Mannagudda, and Markada, showed high turbidity levels. The fluoride concentration in the samples collected from 60 wards of Mangalore city was less than 1.5 ppm, which is the permissible limit by the World Health Organization. Iron is within the permissible limit except for the wards Court and Boloor, which showed an iron concentration of 0.4 ppm and 3.08 ppm, respectively. However, arsenic was not detected in any of the 180 samples collected from the 60 wards of Mangalore City Corporation.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":"13 1","pages":"525 - 534"},"PeriodicalIF":0.3,"publicationDate":"2023-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46656797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left Ventricular Diastolic Dysfunction in Patients with Subclinical Hypothyroidism: A Single South Indian Tertiary Care Centre Study 亚临床甲状腺功能减退症患者的左室舒张功能障碍:一项南印度三级护理中心的单一研究
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-01-20 DOI: 10.1055/s-0042-1760089
Anurag S. Kuchulakanti, Raghav Sharma, Basavaraj Utagi
Abstract Context  Subclinical hypothyroidism (SCH) has been implicated in left ventricular diastolic dysfunction (LVDD). Aims  To study the association between SCH and LVDD. Objectives  To analyze the association between SCH and LVDD. To correlate the amount of LVDD with the serum thyroid-stimulating hormone (TSH) levels. Settings and Design  Single-center case–control study. Methods and Material  A case–control study was conducted between January 2020 and June 2021. A total of 36 cases of SCH were enrolled in the study and 36 age- and gender-matched euthyroid controls were included. Each individual's LV diastolic functioning was assessed by 2D echocardiography. LVDD was graded and compared between cases and controls. Statistical Analysis Used  The sample size was calculated to be 72 based on previous studies. Statistical analysis was performed using the IBM SPSS software version 20. A p -value of less than 0.05 was considered significant. Results  SCH was more commonly seen among females (75%) as compared with males (25%). Among cases, a majority of them (75%) had grade 1 SCH (i.e., TSH < 10 mU/L) and 25% of them had grade 2 SCH (i.e., TSH ≥ 10 mU/L). Among all the parameters assessed for LV diastolic function, the isovolumetric relaxation time and septal E/e' ratio was found to be significantly higher in cases than in controls and mitral E wave deceleration time (DT) significantly lower in cases. A statistically significant majority (72.2%) of the patients with SCH had some form of LVDD as compared with controls (30.5%) Conclusions  Walk-in outpatient department patients who opt for health check-up packages should be screened for SCH. SCH is statistically significantly associated with higher grades of LVDD as compared with age- and gender-matched euthyroid controls.
抽象上下文 亚临床甲状腺功能减退(SCH)与左心室舒张功能障碍(LVDD)有关。目标 研究SCH与LVDD的关系。目标 分析SCH和LVDD之间的关联。将LVDD的量与血清促甲状腺激素(TSH)水平相关联。设置和设计 单中心病例对照研究。方法和材料 在2020年1月至2021年6月期间进行了一项病例对照研究。共有36例SCH病例被纳入研究,36名年龄和性别匹配的甲状腺功能正常对照组被纳入研究。通过二维超声心动图评估每个个体的左心室舒张功能。对LVDD进行分级,并在病例和对照组之间进行比较。使用的统计分析 根据先前的研究,样本量计算为72。使用IBM SPSS软件版本20进行统计分析。p值小于0.05被认为是显著的。后果 SCH在女性(75%)中比男性(25%)更常见。在这些病例中,大多数(75%)患有1级SCH(即TSH < 10mU/L),25%的患者具有2级SCH(即TSH≥10mU/L。在评估左心室舒张功能的所有参数中,发现例患者的等容舒张时间和间隔E/E’比显著高于对照组,例患者的二尖瓣E波减速时间(DT)显著低于对照组。与对照组(30.5%)相比,具有统计学意义的大多数(72.2%)SCH患者患有某种形式的LVDD。结论 选择健康检查套餐的门诊患者应接受SCH筛查。与年龄和性别匹配的甲状腺功能正常对照组相比,SCH在统计学上与更高级别的LVDD显著相关。
{"title":"Left Ventricular Diastolic Dysfunction in Patients with Subclinical Hypothyroidism: A Single South Indian Tertiary Care Centre Study","authors":"Anurag S. Kuchulakanti, Raghav Sharma, Basavaraj Utagi","doi":"10.1055/s-0042-1760089","DOIUrl":"https://doi.org/10.1055/s-0042-1760089","url":null,"abstract":"Abstract Context  Subclinical hypothyroidism (SCH) has been implicated in left ventricular diastolic dysfunction (LVDD). Aims  To study the association between SCH and LVDD. Objectives  To analyze the association between SCH and LVDD. To correlate the amount of LVDD with the serum thyroid-stimulating hormone (TSH) levels. Settings and Design  Single-center case–control study. Methods and Material  A case–control study was conducted between January 2020 and June 2021. A total of 36 cases of SCH were enrolled in the study and 36 age- and gender-matched euthyroid controls were included. Each individual's LV diastolic functioning was assessed by 2D echocardiography. LVDD was graded and compared between cases and controls. Statistical Analysis Used  The sample size was calculated to be 72 based on previous studies. Statistical analysis was performed using the IBM SPSS software version 20. A p -value of less than 0.05 was considered significant. Results  SCH was more commonly seen among females (75%) as compared with males (25%). Among cases, a majority of them (75%) had grade 1 SCH (i.e., TSH < 10 mU/L) and 25% of them had grade 2 SCH (i.e., TSH ≥ 10 mU/L). Among all the parameters assessed for LV diastolic function, the isovolumetric relaxation time and septal E/e' ratio was found to be significantly higher in cases than in controls and mitral E wave deceleration time (DT) significantly lower in cases. A statistically significant majority (72.2%) of the patients with SCH had some form of LVDD as compared with controls (30.5%) Conclusions  Walk-in outpatient department patients who opt for health check-up packages should be screened for SCH. SCH is statistically significantly associated with higher grades of LVDD as compared with age- and gender-matched euthyroid controls.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49502405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Health and Allied Sciences NU
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1