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Handheld electrospinning technologies: a comprehensive review 手持式静电纺丝技术综述
IF 4 1区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-11-08 DOI: 10.1016/j.pmatsci.2025.101614
Ali Bakhshi , Mahya Bakhshi , Mojtaba Hosseine , Hedieh Sadat Shamsnia , Ali Samadi
Handheld electrospinning (HES) devices are a groundbreaking advancement over traditional electrospinning, with increased portability, operating adaptability, and on-demand nanofiber generation. In this review, the complex history of evolution, underlying principles, and system devices facilitating electrospinning are discussed in full detail, with specific emphasis given to heading towards miniaturization and user-focused HES platforms. Mechanisms of fiber formation, types of electrospinning processes, and critical parameters controlling fiber morphology, e.g., solution properties, environmental conditions, and collector geometries, are comprehensively covered. The review also presents a discussion on material selection, encapsulation techniques, and advanced surface engineering techniques to be used in the fabrication of functional nanofibers. Engineering aspects of HES apparatus design, e.g., miniaturization, power supply configurations, nozzle designs, and deposition control, are stringently discussed. Applications of HES from different disciplines, such as wound dressing, wearable electronics, rapid prototyping, and targeted biomedical and environmental applications, are addressed. Regulatory problems, market movements, and available HES products in the market are also addressed, supported by bibliometric and patent analyses that highlight the growth patterns and innovation landscape of the subject area. Preclinical and clinical studies are addressed to put translational progress into perspective, and the key problems in device operation, regulatory compliance, and commercialization are identified. Emerging new future trends, such as AI-enabled optimization, smart biomaterials, transdisciplinary integration, and eco-manufacturing, are highlighted as being essential to achieving breakthroughs in HES technologies. This review will act as a reference point for the development, implementation, and extension of HES in research and applied environments.
手持式静电纺丝(HES)设备是传统静电纺丝的突破性进步,具有更高的便携性、操作适应性和按需生产纳米纤维。在这篇综述中,详细讨论了静电纺丝复杂的发展历史、基本原理和促进静电纺丝的系统设备,并特别强调了朝着小型化和以用户为中心的HES平台的方向发展。纤维的形成机制,静电纺丝工艺的类型,以及控制纤维形态的关键参数。,解决方案的性质,环境条件和收集器的几何形状,全面覆盖。综述了功能型纳米纤维的材料选择、封装技术和先进的表面工程技术。工程方面的HES设备设计,例如,小型化,电源配置,喷嘴设计和沉积控制,严格讨论。从不同学科的应用,如伤口敷料,可穿戴电子,快速原型,有针对性的生物医学和环境应用,解决了HES。还讨论了监管问题、市场变动和市场上可用的HES产品,并通过文献计量学和专利分析提供支持,这些分析突出了主题领域的增长模式和创新前景。临床前和临床研究旨在将转化进展置于正确的角度,并确定了设备操作,法规遵从性和商业化方面的关键问题。新兴的未来趋势——如人工智能优化、智能生物材料、跨学科整合和生态制造——被强调为实现HES技术突破的关键。本综述将作为在研究和应用环境中开发、实施和扩展HES的参考点。
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引用次数: 0
Advancements in cathode materials for dual-ion batteries 双离子电池正极材料研究进展
IF 4 1区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-11-03 DOI: 10.1016/j.pmatsci.2025.101600
Zhiqin Sun , Honglei Jiang , Pei Liu, Ting Jin, Lifang Jiao
Different from traditional batteries, dual-ion batteries (DIBs) operate via a mechanism in which both cations and anions actively participate in electrochemical reactions at their respective electrodes. This distinctive feature enables DIBs to achieve higher operating voltages, leading to greater energy output. Given that cathode materials play a pivotal role in anion storage, their performance directly determines the overall efficiency of DIBs. However, the limited specific capacity and poor interfacial stability of cathodes remain bottlenecks that hinder the advancement of DIBs. Therefore, a systematic evaluation and comprehensive overview of recent research progress are critically needed. In this review, we analyze the key challenges faced by cathode materials in DIBs and highlight strategies employed to optimize these materials for enhanced anion storage. By consolidating recent research insights, this review aims to guide the development of high-performance DIBs.
与传统电池不同的是,双离子电池(DIBs)是通过阳离子和阴离子在各自的电极上参与电化学反应的机制发挥作用的。这种独特的特性使dib能够实现更高的工作电压,从而产生更大的能量输出。由于阴极材料在阴离子存储中起着关键作用,其性能直接决定了dib的整体效率。然而,阴极有限的比容量和较差的界面稳定性仍然是阻碍dib发展的瓶颈。因此,对最近的研究进展进行系统的评价和全面的综述是必要的。在这篇综述中,我们分析了dib中阴极材料目前面临的挑战,并重点介绍了优化这些材料以增强阴离子存储的策略。通过综合这些见解,本文旨在指导高性能dib的开发。
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引用次数: 0
Self-adaptive biomaterials for tissue repair: from design to application 组织修复用自适应生物材料:从设计到应用
IF 4 1区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-10-31 DOI: 10.1016/j.pmatsci.2025.101593
Weiwei Zheng , Zeyuan Jin , Xiping Chen , Qiaoxuan Wang , Yongyuan Kang , Jieting Chang , Pai Peng , Beiduo Wang , Changyou Gao
Biomaterials that can facilitate tissue repair following injury caused by trauma, diseases and aging are highly demanded for the innovation of medicinal and pharmaceutical applications. Self-adaptive biomaterials represent a new class of functional biomaterials designed to interactively regulate the pathological tissue microenvironment post-injury to promote tissue repair in an adaptive manner. This dynamic adaptive interaction involves the biomaterials reacting to the biological cues of tissue microenvironment, which in turn influences the structure and compositions of the biomaterials, creating a feedback loop. In this review, we systematically summarize the components of the inflammatory microenvironment after tissue injury, and underscore its key characteristics and modulation principles, which are instrumental in guiding the design of self-adaptive biomaterials. Subsequently, we outline the current self-adaptive biomaterials, detailing their structures and functionalities. Furthermore, we elaborate the state-of-the-art of their biomedical applications in tissue repair. Additionally, we discuss the challenges and future perspectives of self-adaptive biomaterials in the design of therapeutic strategies and their potential for future clinical applications in tissue repair. It is anticipated that the self-adaptive biomaterials will provide valuable insights and guide the direction of biomaterial development for tissue repair applications.
生物材料可以促进创伤、疾病和衰老引起的组织损伤的修复,这是医疗和制药应用创新的高度需求。自适应生物材料是一类新型的功能生物材料,旨在通过相互作用调节损伤后病理组织微环境,以适应性方式促进组织修复。这种动态的自适应相互作用涉及到生物材料对组织微环境的生物信号的反应,这反过来影响生物材料的结构和组成,形成一个反馈回路。本文系统总结了组织损伤后炎症微环境的组成,强调了炎症微环境的主要特征和调节原理,这对指导自适应生物材料的设计具有重要意义。随后,我们概述了目前的自适应生物材料,详细介绍了它们的结构和功能。此外,我们详细介绍了最新的生物医学在组织修复中的应用。此外,我们还讨论了自适应生物材料在治疗策略设计中的挑战和未来前景,以及它们在组织修复中的未来临床应用潜力。预计自适应生物材料将为组织修复应用提供有价值的见解和指导生物材料的发展方向。
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引用次数: 0
Innovative carbon-based materials for efficient hydrogen storage: A review of solid, gaseous, and liquid systems 用于高效储氢的创新碳基材料:固体、气体和液体系统综述
IF 4 1区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-10-31 DOI: 10.1016/j.pmatsci.2025.101596
Jieduo Guan , Chengguang Lang , Xiangdong Yao
Hydrogen (H2) stands as a cornerstone of sustainable energy and an indispensable pathway toward achieving carbon neutrality. Yet, the advancement of the hydrogen economy is significantly impeded by challenges related to storage and transportation. Conventional storage strategies—primarily high-pressure gaseous storage—rely on expensive fiber-reinforced composite tanks that not only escalate costs but also suffer from low efficiency and notable safety concerns. This scenario underscores the critical need for hydrogen storage solutions that are safe, efficient, and economically viable. Carbon-based materials have emerged as a compelling alternative, offering robust hydrogen storage capabilities via both physical adsorption and chemical bonding. These materials promise enhanced safety and improved efficiency for hydrogen transport. This review comprehensively examines the state-of-the-art developments in hydrogen storage across three distinct categories of carbon-based materials: solid carbon materials, gaseous carbon dioxide (CO2) hydrogen carrier, and liquid organic hydrogen carriers. Moreover, it critically evaluates the reversibility of these storage mechanisms and explores their potential for commercial application, providing insight into their role in the future of the hydrogen economy. This refined exploration aims to guide future research at the intersection of material science and energy technology, fostering innovations that may eventually overcome the current barriers in hydrogen storage and utilization.
氢(H2)是可持续能源的基石,也是实现碳中和不可或缺的途径。然而,氢经济的发展受到与储存和运输相关的挑战的严重阻碍。传统的储存策略——主要是高压气体储存——依赖于昂贵的纤维增强复合材料储罐,这不仅增加了成本,而且效率低,而且存在明显的安全问题。这种情况强调了对安全、高效、经济可行的储氢解决方案的迫切需求。碳基材料已经成为一种引人注目的替代方案,通过物理吸附和化学键结合提供强大的储氢能力。这些材料有望提高氢气运输的安全性和效率。本文全面考察了三种不同类别的碳基材料在储氢方面的最新发展:固体碳材料、气态二氧化碳(CO2)氢载体和液态有机氢载体。此外,它批判性地评估了这些储存机制的可逆性,并探索了它们的商业应用潜力,为它们在未来氢经济中的作用提供了见解。这项精细化的探索旨在指导未来材料科学和能源技术交叉领域的研究,促进创新,最终克服目前氢储存和利用方面的障碍。
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引用次数: 0
A constructive perspective on ionic self-powered pressure sensing 离子自供电压力传感的建设性观点
IF 4 1区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-10-30 DOI: 10.1016/j.pmatsci.2025.101595
Mingfang Deng, Ziqi Ren, Jianyu Yin, Xubin Zhou, Liangxian Wang, Nishuang Liu
The growing demand from flexible and wearable electronic systems for devices that simultaneously offer autonomous energy supply and high-sensitivity pressure sensing has accelerated the development of self-powered pressure sensors. Although substantial research has been conducted on either energy harvesting or pressure sensing mechanisms, most efforts have primarily focused on performance enhancement, lacking a systematic examination of the coupling between energy conversion and pressure response processes. This absence of integration logic hinders the rational design of fully functional devices. This review centers on the critical intersection of ionic materials, self-powered energy conversion, and pressure sensing. It systematically summarizes ion-involved energy harvesting mechanisms such as triboelectric, piezoionic, along with pressure sensing methods that can be coupled with them. Structural design approaches, including porous architectures, gradient structures and so on , are further examined for their roles in enhancing ion transport regulation. Finally, the review outlines current applications in intelligent tactile interfaces, human communication aids, and other related areas. By adopting a unified perspective that connects mechanism, structure, and function, this work proposes a scalable design strategy for self-powered pressure sensors, offering a conceptual framework for future device development and system-level integration.
灵活和可穿戴电子系统对同时提供自主能源供应和高灵敏度压力传感的设备的需求不断增长,加速了自供电压力传感器的发展。尽管已经对能量收集或压力传感机制进行了大量研究,但大多数努力主要集中在性能增强上,缺乏对能量转换和压力响应过程之间耦合的系统检查。这种集成逻辑的缺失阻碍了功能齐全的器件的合理设计。本文综述了离子材料、自供电能量转换和压力传感的关键交叉点。它系统地总结了离子涉及的能量收集机制,如摩擦电,压电离子,以及可以与它们耦合的压力传感方法。结构设计方法,包括多孔结构、梯度结构等,进一步研究了它们在增强离子传输调节中的作用。最后,综述概述了目前在智能触觉界面、人类交流辅助和其他相关领域的应用。通过采用连接机制、结构和功能的统一视角,本研究提出了一种可扩展的自供电压力传感器设计策略,为未来的设备开发和系统级集成提供了概念框架。
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引用次数: 0
Corrigendum to “Roadmap for integrating deep eutectic solvents into adsorption processes: A critical review & design blueprint” [Progress Mater. Sci. 154 (2025) 101501] “将深共晶溶剂整合到吸附过程的路线图:一个关键的审查和设计蓝图”的勘误表[进展材料]。科学通报。154 (2025)101501]
IF 4 1区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-10-29 DOI: 10.1016/j.pmatsci.2025.101598
Ghaiath Almustafa , Rawan Abu Alwan , Ho Kyong Shon , Jorge Rodriguez , Inas AlNashef
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引用次数: 0
Recent progress in rare earth element modulated electrocatalysts for CO2 electroreduction 稀土元素调制CO2电还原电催化剂研究进展
IF 4 1区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-10-24 DOI: 10.1016/j.pmatsci.2025.101594
Yin Wang , Wensheng Fang , Deyu Zhu , Jiwen Chen , Xin Wang , Ho Seok Park , Jinghai Liu , Bao Yu Xia
Electrocatalytic CO2 reduction reaction (CO2RR) represents a highly promising carbon-negative technology, capable of mitigating atmospheric CO2 concentrations while simultaneously generating value-added chemicals. Rare earth (RE) elements have been extensively used to fabricate advanced electrocatalysts for enhancing the performance of CO2RR due to their unique 4f electron configurations and redox characteristics. However, critical challenges of achieving precise modulation on CO2 selectivity with RE elements and their mechanisms are still being pursued. This review systematically summarizes recent advances in RE-based electrocatalysts for selective conversion of CO2 towards each C1 (CO, HCOOH/HCOO and CH4) or C2+ (C2H4, C2H5OH) products, and aims to construct the relationship between the RE-mediated structure and electrocatalytic performance. Primarily, the fundamental aspects of CO2RR selectivity and RE characteristics are established. Subsequently, selective modulation mechanisms for specific CO2RR product and corresponding RE-based catalysts are proposed and classified. We elucidate the synergistic modulation on CO2 reduction pathway by RE elements unique physicochemical properties (including 4f-electron properties, larger atomic radius, oxygen affinity, and high-valence state) in critical reaction metrics: CO2 activation, *CO adsorption energy, C–C coupling kinetics, electron/mass transport efficiency and long-term catalytic stability. Building on this foundation, atomic-level control over Cu/RE ratio governs the selective generation of C1 versus C2+ products by modulating reaction pathways, while the intrinsic high-valence stability of RE effectively enhances catalytic durability. Finally, we outline the current challenges and future research directions for RE-mediated CO2RR systems. This review will offer rational principles and deeper understanding for engineering RE-based electrocatalysts toward desired chemicals under industrial-scale CO2RR.
电催化二氧化碳还原反应(CO2RR)是一种非常有前途的负碳技术,能够在减少大气二氧化碳浓度的同时产生增值化学品。稀土元素由于其独特的4f电子构型和氧化还原特性,已被广泛用于制造先进的电催化剂,以提高CO2RR的性能。然而,利用稀土元素实现对CO2选择性的精确调制及其机制仍是一个重要的挑战。本文系统地综述了re基电催化剂在CO2选择性转化为C1 (CO, HCOOH/HCOO−和CH4)或C2+ (C2H4, C2H5OH)产物方面的最新进展,旨在构建re介导的结构与电催化性能之间的关系。首先,建立了CO2RR选择性和RE特性的基本方面。随后,提出并分类了特定CO2RR产物的选择性调制机制和相应的re基催化剂。我们阐明了稀土元素独特的物理化学性质(包括4f电子性质、更大的原子半径、氧亲和和高价态)在CO2活化、*CO吸附能、C-C耦合动力学、电子/质量传递效率和长期催化稳定性等关键反应指标上对CO2还原途径的协同调节。在此基础上,原子水平上对Cu/RE比的控制通过调节反应途径来控制C1和C2+产物的选择性生成,而RE固有的高价稳定性有效地提高了催化耐久性。最后,我们概述了re介导的CO2RR系统目前面临的挑战和未来的研究方向。本文综述将为工业规模CO2RR条件下的工程稀土电催化剂催化所需化学物质提供合理的原理和更深入的认识。
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引用次数: 0
Organic coating failure and monitoring in atmospheric corrosion: from mechanisms to applications 大气腐蚀中的有机涂层失效和监测:从机理到应用
IF 4 1区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-10-21 DOI: 10.1016/j.pmatsci.2025.101592
Xianlian Mu , Tao Jin , Pengfei Xie , Rongcao Yu , Shengnan Hu , Bin Li , Lei Li , Xin Yuan
The failure of organic coatings protecting metal structures in aerospace and marine engineering under atmospheric corrosion has become a critical threat to structural safety. The NACE report indicates that 38 % of global corrosion costs stem from coating failure. This data is directly associated with the accelerated failure of the coating’s physical barrier caused by Cl in the marine atmosphere (diffusion coefficient D ≈ 5 × 10−11 cm2/s). This review focuses on organic coatings for metal structures and constructs a systematic scenario-mechanism-technology-model framework: ① Analyze three core environmental characteristics—electrochemical catalytic effects of SO2/NOx in industrial atmospheres, deliquescence-crystallization cycles of Cl in marine atmospheres, and synergistic effects of hypoxia, low temperature, and intense UV in aerospace high-altitude environments; ② Reveal multi-scale failure mechanisms: molecular-level degradation (e.g., ester bond hydrolysis in epoxy resins, C-F bond cleavage in fluorocarbon coatings), microscale defect propagation, and macroscopic delamination, establishing a medium penetration-interface reaction-structural deterioration failure clock model; ③ Compare monitoring technologies (EIS has a 12 % false negative rate in marine environments, SKP achieves 89 % accuracy in aerospace interface debonding early warning) and evaluate prediction models (Arrhenius empirical model shows > 20 % error at high temperatures, LSTM-GARCH model achieves < 10 % error under multi-factor conditions). Key bottlenecks identified include: lack of cross-scale modeling for multi-factor synergistic failure, engineering obstacles for self-healing smart coatings, and heavy data dependence of AI models. Future research should focus on quantifying physical-electrochemical coupling mechanisms and integrating fiber optic sensing with digital twins to provide lifecycle protection for high-end equipment coatings.
航空航天和海洋工程中保护金属结构的有机涂层在大气腐蚀作用下的失效已成为威胁结构安全的重要问题。NACE报告指出,全球38%的腐蚀成本源于涂层失效。这一数据与海洋大气中Cl−引起的涂层物理屏障加速失效(扩散系数D≈5 × 10−11 cm2/s)直接相关。本文以金属结构有机涂层为研究重点,构建了系统的场景-机制-技术-模型框架:①分析了工业大气中SO2/NOx的电化学催化效应、海洋大气中Cl−的潮解-结晶循环以及航空航天高空环境中缺氧、低温和强紫外线的协同效应三个核心环境特征;②揭示了多尺度失效机制:分子水平的降解(如环氧树脂中的酯键水解、氟碳涂料中的C-F键解理)、微观尺度的缺陷扩展、宏观层面的分层,建立了介质渗透-界面反应-结构劣化失效时钟模型;③比较监测技术(EIS在海洋环境中假阴性率为12%,SKP在航空航天界面剥离预警中准确率为89%)和评估预测模型(Arrhenius经验模型在高温条件下误差为20%,LSTM-GARCH模型在多因素条件下误差为10%)。确定的主要瓶颈包括:缺乏多因素协同故障的跨尺度建模,自我修复智能涂层的工程障碍,以及人工智能模型对数据的严重依赖。未来的研究应侧重于量化物理-电化学耦合机制,并将光纤传感与数字孪生相结合,为高端设备涂层提供生命周期保护。
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引用次数: 0
4D printing for bone implant: Progress, advantages and challenges 骨种植体的4D打印:进展、优势和挑战
IF 4 1区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-10-15 DOI: 10.1016/j.pmatsci.2025.101591
Feng Yang , Wenjing Ding , Jiye Jia , Cijun Shuai , Pei Feng
While the dynamic characteristic of 4D printing empowers the original static objects fabricated by 3D printing to adapt to more complex application scenarios, their efficacy in orchestrating sophisticated tissue regeneration processes remains controversial given the pathophysiological complexity of native tissues. It is particularly noteworthy that significant changes in properties such as mechanical strength during dynamic transformation pose challenges for its application in load-bearing tissues like bone, warranting further research. Here, 4D printed bone implants were taken as the research objects, beginning with the construction strategies where the advantages of 4D printing over 3D printing in bone tissue engineering were also summarized, leading to the structural design and fabrication techniques of 4D printed bone implants. Then, three major challenges focused on shape transformation, stimulation methods and mechanical strength that 4D printed bone implants faced in practical applications were emphasized in sequence, with corresponding solutions being summarized. Overall, this review systematically analyzed both the advantages and challenges of 4D printed bone implants in the treatment of bone defects, aiming to facilitate the development of intelligent bone implants and accelerate the transition of 4D printed bone implants from basic research to clinical application.
虽然4D打印的动态特性使3D打印制造的原始静态物体能够适应更复杂的应用场景,但考虑到原生组织的病理生理复杂性,它们在协调复杂组织再生过程中的功效仍然存在争议。特别值得注意的是,动态转化过程中机械强度等性能的显著变化,对其在骨等承重组织中的应用提出了挑战,值得进一步研究。本文以4D打印骨植入物为研究对象,从构建策略入手,总结了4D打印相对于3D打印在骨组织工程中的优势,进而提出了4D打印骨植入物的结构设计和制造技术。然后依次强调了4D打印骨植入物在实际应用中面临的形状转化、刺激方式和机械强度三大挑战,并总结了相应的解决方案。综上所述,本文系统分析了4D打印骨种植体在骨缺损治疗中的优势和挑战,旨在促进智能骨种植体的发展,加快4D打印骨种植体从基础研究向临床应用的过渡。
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引用次数: 0
Biodegradable zinc-based metallic materials: Mechanisms, properties, and applications 可生物降解的锌基金属材料:机理、性能和应用
IF 4 1区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-10-15 DOI: 10.1016/j.pmatsci.2025.101584
Hongtao Yang , He Huang , Shuang Li , Yu Qin , Peng Wen , Xinhua Qu , Bo Jia , Yufeng Zheng
Zinc (Zn) and its alloys have rapidly emerged as biodegradable metals with promising biomedical applications over the past decade. Their unique advantages include tunable degradation rates that align well with tissue healing, diverse biofunctions, and superior mechanical properties. These attributes position Zn alloys as a potential breakthrough for expanding the clinical utility of biodegradable materials and addressing existing technical challenges. This review begins with a historical development of industrial Zn alloys and Zn biology, highlighting the interdisciplinary efforts that gave rise to biodegradable Zn alloys, and the comparison of metallic Zn with other biodegradable metals and Zn-based biomaterials. We then examine the biodegradation process of Zn metals in physiological environments, focusing on material and environmental factors influencing degradation behavior and potential metabolic pathways of Zn degradation products. The biological functions of Zn alloy implants, including osteogenesis, antibacterial activity, angiogenesis, immunomodulation, and anti-restenosis effects, are discussed. Next, critical mechanical properties, such as strength, ductility, stiffness, fatigue, and creep, are also analyzed, along with factors that influence these properties. Furthermore, we explore the performance of Zn alloy implants in cardiovascular, orthopedic, and wound closure applications. Finally, we discuss challenges that must be addressed to facilitate clinical translation of Zn alloys and outline promising future directions including AI assisted design and “smart” Zn biomaterials for precision medicine.
近十年来,锌及其合金作为生物可降解金属迅速崛起,具有广阔的生物医学应用前景。其独特的优势包括可调节的降解率,与组织愈合,多样化的生物功能和优越的机械性能相匹配。这些特性使锌合金成为扩大生物可降解材料临床应用和解决现有技术挑战的潜在突破。本文从工业锌合金和锌生物学的历史发展开始,重点介绍了生物可降解锌合金的跨学科研究,以及金属锌与其他生物可降解金属和锌基生物材料的比较。然后,我们研究了锌金属在生理环境中的生物降解过程,重点研究了影响降解行为的内在和外在因素以及锌降解产物的潜在代谢途径。本文讨论了锌合金植入物的生物学功能,包括成骨、抗菌、血管生成、免疫调节和抗再狭窄作用。其次,关键的机械性能,如强度,延展性,刚度,疲劳和蠕变,也进行了分析,以及影响这些性能的因素。此外,我们还探讨了锌合金植入物在心血管、骨科和伤口愈合方面的应用。最后,我们讨论了必须解决的挑战,以促进锌合金的临床翻译,并概述了有希望的未来方向,包括人工智能辅助设计和用于精准医疗的“智能”锌生物材料。
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引用次数: 0
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