Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.9.2_77
M. Okazaki, S. Fujikawa, N. Matsumoto
Xylooligosaccharide was found to have a favorable effect on human intestinal flora. Xylooligosaccharide was utilized by bifidobacteria, but it was not utilized by Escherichia coli and Clostridium spp. in vitro. In vivo, xylooligosaccharide (5 g/day) promoted the growth of bifidobacteria, lowered fecal pH and helped to maintain the fecal water content within normal range. These results showed that xylooligosaccharide can selectively promote the growth of bifidobacteria and help to establish favorable environmental conditions in the intestines.
{"title":"Effect of Xylooligosaccharide on the Growth of Bifidobacteria","authors":"M. Okazaki, S. Fujikawa, N. Matsumoto","doi":"10.12938/BIFIDUS1982.9.2_77","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.9.2_77","url":null,"abstract":"Xylooligosaccharide was found to have a favorable effect on human intestinal flora. Xylooligosaccharide was utilized by bifidobacteria, but it was not utilized by Escherichia coli and Clostridium spp. in vitro. In vivo, xylooligosaccharide (5 g/day) promoted the growth of bifidobacteria, lowered fecal pH and helped to maintain the fecal water content within normal range. These results showed that xylooligosaccharide can selectively promote the growth of bifidobacteria and help to establish favorable environmental conditions in the intestines.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127271872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.11.1_39
E. Isogai, H. Isogai, N. Fujii, K. Hirose, H. Wakizaka, H. Miura, F. Yoshimura
Fimbriae from Porphyromonas gingivalis were found to induce an early chemiluminescence response of mouse peritoneal macrophages. A significant dose-dependent increase in the response was observed. The response induced by the fimbriae was different from that induced by the lipopolysaccharide (LPS) . Viable P. gingivalis whole cells stimulated macrophages and the chemiluminescence response cojoined the two responses induced by fimbriae and LPS. These observations suggest that P. gingivalis fimbriae may be involved in the pathogenesis of adult periodontal disease via the triggering of reactive oxygen intermediates by macrophages in the disease in a different manner to its LPS.
{"title":"Fimbriae from Porphyromonas gingivalis Induce Chemiluminescence Response of Macrophages in a Different Manner to Its Lipopolysaccharide","authors":"E. Isogai, H. Isogai, N. Fujii, K. Hirose, H. Wakizaka, H. Miura, F. Yoshimura","doi":"10.12938/BIFIDUS1982.11.1_39","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.11.1_39","url":null,"abstract":"Fimbriae from Porphyromonas gingivalis were found to induce an early chemiluminescence response of mouse peritoneal macrophages. A significant dose-dependent increase in the response was observed. The response induced by the fimbriae was different from that induced by the lipopolysaccharide (LPS) . Viable P. gingivalis whole cells stimulated macrophages and the chemiluminescence response cojoined the two responses induced by fimbriae and LPS. These observations suggest that P. gingivalis fimbriae may be involved in the pathogenesis of adult periodontal disease via the triggering of reactive oxygen intermediates by macrophages in the disease in a different manner to its LPS.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130618666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.11.2_53
E. Isogai, H. Isogai, N. Fujii, K. Kimura, H. Miura, M. Hayashi, S. Namioka, Masayoshi Kawasaki, Kunihiko Ikeda
The ethanol extracts from Japanese green tea from the leaf of Camellia sinensis (Japanese green tea) contained polyphenol compounds as major components. By liquid and gas chromatographic analysis, 5 catechin compounds were detected. The tea extracts (Deochon 13189-B, Deochon 30 EX and Camellia 50 EX) were found to effectively inhibit the growth of canine oral bacteria. Minimum inhibitory concentration (MIC) was different among genus, species and strains of the bacteria. Canine periodontal pathogens such as Porphyromonas assacharolytica were sensitive to the tea extracts. Similar result was obtained by using human oral bacteria including periodontal pathogens. These results suggest that the tea extracts would be useful as anti-periodontitis agent and/or flora control agent in dogs.
{"title":"Inhibitory Effect of Japanese Green Tea Extracts on Growth of Canine Oral Bacteria","authors":"E. Isogai, H. Isogai, N. Fujii, K. Kimura, H. Miura, M. Hayashi, S. Namioka, Masayoshi Kawasaki, Kunihiko Ikeda","doi":"10.12938/BIFIDUS1982.11.2_53","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.11.2_53","url":null,"abstract":"The ethanol extracts from Japanese green tea from the leaf of Camellia sinensis (Japanese green tea) contained polyphenol compounds as major components. By liquid and gas chromatographic analysis, 5 catechin compounds were detected. The tea extracts (Deochon 13189-B, Deochon 30 EX and Camellia 50 EX) were found to effectively inhibit the growth of canine oral bacteria. Minimum inhibitory concentration (MIC) was different among genus, species and strains of the bacteria. Canine periodontal pathogens such as Porphyromonas assacharolytica were sensitive to the tea extracts. Similar result was obtained by using human oral bacteria including periodontal pathogens. These results suggest that the tea extracts would be useful as anti-periodontitis agent and/or flora control agent in dogs.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134008031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.10.2_89
Y. Benno, T. Mitsuoka
The incidence of colon cancer varies widely throughout the world (8, 9). It has been demonstrated that the disease is much rarer in Africa, Asia, and South America than in Western Europe or North America (37) . The reason for this variation is unclear but epidemiological studies, focusing on genetic , cultural, environmental and economic factors suggest that the diet, in particular an increased intake of fat and animal protein, is strongly correlated with the incidence of colon cancer (19, 36) . Epidemiologic studies (7, 31, 36) also suggest that decreases in dietary fiber intake actually increase the incidence of several colonic disorders including: diverticular disease, cancer and constipation. Since some of the predominating bacteria in human fecal contents ferment various types of hemicelluloses (34), it would be of interest to determine the effects, if any, of dietary fiber on the human fecal flora. It is widely known that the composition of fecal flora in healthy infants differed according to the mode of feeding (2, 18, 23) . Although taxonomic studies on Bifidobacterium species present in feces of babies have been carried out (25, 32), the bulk of anaerobes and aerobes from their feces have not been identified at the species level. To address the aforementioned, the present studies were undertaken. Thus, the composition of the fecal flora of the following subjects were compared : (i) breastfed versus bottle-fed infants, (ii) rural Japanese with a low incidence of colon cancer , (iii) urban Canadians with a high incidence of colon cancer, (iv) Japanese volunteers given a high beef or a rice fiber diet (particularly brown rice), and (v) elderly Japanese in rural (Yuzurihara, Uenohara, Yamanashi Prefecture) and urban (Tokyo) areas of Japan, respectively.
{"title":"Effect of Diet and Aging on Human Fecal Microflora","authors":"Y. Benno, T. Mitsuoka","doi":"10.12938/BIFIDUS1982.10.2_89","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.10.2_89","url":null,"abstract":"The incidence of colon cancer varies widely throughout the world (8, 9). It has been demonstrated that the disease is much rarer in Africa, Asia, and South America than in Western Europe or North America (37) . The reason for this variation is unclear but epidemiological studies, focusing on genetic , cultural, environmental and economic factors suggest that the diet, in particular an increased intake of fat and animal protein, is strongly correlated with the incidence of colon cancer (19, 36) . Epidemiologic studies (7, 31, 36) also suggest that decreases in dietary fiber intake actually increase the incidence of several colonic disorders including: diverticular disease, cancer and constipation. Since some of the predominating bacteria in human fecal contents ferment various types of hemicelluloses (34), it would be of interest to determine the effects, if any, of dietary fiber on the human fecal flora. It is widely known that the composition of fecal flora in healthy infants differed according to the mode of feeding (2, 18, 23) . Although taxonomic studies on Bifidobacterium species present in feces of babies have been carried out (25, 32), the bulk of anaerobes and aerobes from their feces have not been identified at the species level. To address the aforementioned, the present studies were undertaken. Thus, the composition of the fecal flora of the following subjects were compared : (i) breastfed versus bottle-fed infants, (ii) rural Japanese with a low incidence of colon cancer , (iii) urban Canadians with a high incidence of colon cancer, (iv) Japanese volunteers given a high beef or a rice fiber diet (particularly brown rice), and (v) elderly Japanese in rural (Yuzurihara, Uenohara, Yamanashi Prefecture) and urban (Tokyo) areas of Japan, respectively.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130498198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.12.2_87
T. Fujisawa, K. Itoh, T. Mitsuoka
Total 286 strains of lactobacilli were isolated from different segments of the alimentary tract of healthy horses. They were identified by the carbohydrate fermentation patterns and physiological properties as L. salivarius (10 biovars), L. acidophilus (8 biovars), L. reuteri (8 biovars) and Lactobacillus spp. (2 biovars). L. acidophilus and L. reuteri were found in all parts of the alimentary tract, while L. salivarius were not isolated from the stomach. The unidentified Lactobacillus spp. were isolated only from feces.
{"title":"Lactobacilli in the Alimentary Tract of Horses","authors":"T. Fujisawa, K. Itoh, T. Mitsuoka","doi":"10.12938/BIFIDUS1982.12.2_87","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.12.2_87","url":null,"abstract":"Total 286 strains of lactobacilli were isolated from different segments of the alimentary tract of healthy horses. They were identified by the carbohydrate fermentation patterns and physiological properties as L. salivarius (10 biovars), L. acidophilus (8 biovars), L. reuteri (8 biovars) and Lactobacillus spp. (2 biovars). L. acidophilus and L. reuteri were found in all parts of the alimentary tract, while L. salivarius were not isolated from the stomach. The unidentified Lactobacillus spp. were isolated only from feces.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124440401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.3.1_43
K. Yazawa, A. Nakajima, Z. Tamura
Among 45 Bifidobacterium strains of adult origin , all required a sugar source (ex. lactose) and pantethine (or pantothenic acid), 35 strains required riboflavin , and 12 required thiamine as essential nutrients . Fifteen strains were able to grow on pantothenic acid as well as pantethine. Fewer than 9 strains required other nutrients. The sugar source (10 to 15 g/day), pantethine (50 mg/day) and riboflavin (5 mg/day) were orally administered to 2 healthy adults whose proportion of bifidobacteria in the intestinal florae was usually very low (less than 1% of total bacterial number) . The sugar source was lactulose, raffinose or inulin. Pantethine and riboflavin were packed together in capsules and enteric-coated. Administration of both sugar source and vitamin capsules caused marked growth of bifidobacteria (more than 40% of total bacterial number) in both adults. Administration of the sugar source alone caused moderate growth of bifidobacteria (13%), while administration of the vitamin capsules alone was ineffective. These results indicate that the sugar source is essential for growth of bifidobacteria in adults, as well as in infants, and that administration of pantethine and riboflavin is important.
{"title":"Growth of Bifidobacteria in Adults' Intestines on Oral Administration of Sugar Source, Pantethine and Riboflavin","authors":"K. Yazawa, A. Nakajima, Z. Tamura","doi":"10.12938/BIFIDUS1982.3.1_43","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.3.1_43","url":null,"abstract":"Among 45 Bifidobacterium strains of adult origin , all required a sugar source (ex. lactose) and pantethine (or pantothenic acid), 35 strains required riboflavin , and 12 required thiamine as essential nutrients . Fifteen strains were able to grow on pantothenic acid as well as pantethine. Fewer than 9 strains required other nutrients. The sugar source (10 to 15 g/day), pantethine (50 mg/day) and riboflavin (5 mg/day) were orally administered to 2 healthy adults whose proportion of bifidobacteria in the intestinal florae was usually very low (less than 1% of total bacterial number) . The sugar source was lactulose, raffinose or inulin. Pantethine and riboflavin were packed together in capsules and enteric-coated. Administration of both sugar source and vitamin capsules caused marked growth of bifidobacteria (more than 40% of total bacterial number) in both adults. Administration of the sugar source alone caused moderate growth of bifidobacteria (13%), while administration of the vitamin capsules alone was ineffective. These results indicate that the sugar source is essential for growth of bifidobacteria in adults, as well as in infants, and that administration of pantethine and riboflavin is important.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123330251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.11.2_69
Y. Benno, H. Nakao, K. Uchida, T. Mitsuoka
The fecal specimens from eight laboratory-bred male beagle dogs reared under similar conditions were analyzed for the individual variation and the seasonal variation in the composition of fecal microflora. Statistically significant differences in numbers of bacteroides, bifidobacteria, lecithinase-negative clostridia, lactobacilli, enterobacteria and enterococci were observed among individual animals. Megasphaera elsdenii was isolated from two of eight dogs. The microbial populations of bacteroides, clostridia, bifidobacteria, and peptostreptococci were associated with each other bacterial group. The seasonal variation in numbers of lecithinasenegative clostridia, Clostridium perfringens, peptostreptococci, enterococci, eubacteria, bifidobacteria, and lactobacilli, and in the incidences of staphylococci, bacilli, and yeasts were noted. The results of this study showed that apparent variations with individuals and season occurred on the fecal microflora of individual beagle dogs reared under similar conditions.
{"title":"Individual and Seasonal Variations in the Composition of Fecal Microflora of Beagle Dogs","authors":"Y. Benno, H. Nakao, K. Uchida, T. Mitsuoka","doi":"10.12938/BIFIDUS1982.11.2_69","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.11.2_69","url":null,"abstract":"The fecal specimens from eight laboratory-bred male beagle dogs reared under similar conditions were analyzed for the individual variation and the seasonal variation in the composition of fecal microflora. Statistically significant differences in numbers of bacteroides, bifidobacteria, lecithinase-negative clostridia, lactobacilli, enterobacteria and enterococci were observed among individual animals. Megasphaera elsdenii was isolated from two of eight dogs. The microbial populations of bacteroides, clostridia, bifidobacteria, and peptostreptococci were associated with each other bacterial group. The seasonal variation in numbers of lecithinasenegative clostridia, Clostridium perfringens, peptostreptococci, enterococci, eubacteria, bifidobacteria, and lactobacilli, and in the incidences of staphylococci, bacilli, and yeasts were noted. The results of this study showed that apparent variations with individuals and season occurred on the fecal microflora of individual beagle dogs reared under similar conditions.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124756713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.9.2_87
I. Suzuki, K. Hashimoto, T. Yadomae
The preparation of cells of Peyer's patches (PP) from mice and some immunological activities of the cells were examined. The PP cells were obtained with high yield (> 1 •~ 107/CDF1 mouse) and viability (>97%), when the PP were cut and teased gently with two glasses in RPMI 1640 medium containing 5% heat-inactivated calf serum. The PP cells responded well to mitogens, and particularly the responses to a T cell mitogen, concanavalin A (Con A), were at similar levels to those of spleen cells. When the cells were stimulated with alloantigens in mixed lymphocyte reaction, significant response was observed. The PP cells cultured with lipopolysaccharide (LPS) exhibited polyclonal B cell responses (antigen-nonspecific increase in the number of antibody-producing cells) . Furthermore, the levels of anti sheep erythrocytes (SRBC) plaque-forming cells (PFC) in PP cell cultures increased significantly when the PP cells were cultured with SRBC in vitro. However, the PP cells did not show the natural killer (NK) activity. These results showed that the PP cells obtained by the physical method described here contained functionable T and B lymphocytes and accessory cells.
{"title":"Rapid Preparation of Functional Murine Peyer's Patch Cells","authors":"I. Suzuki, K. Hashimoto, T. Yadomae","doi":"10.12938/BIFIDUS1982.9.2_87","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.9.2_87","url":null,"abstract":"The preparation of cells of Peyer's patches (PP) from mice and some immunological activities of the cells were examined. The PP cells were obtained with high yield (> 1 •~ 107/CDF1 mouse) and viability (>97%), when the PP were cut and teased gently with two glasses in RPMI 1640 medium containing 5% heat-inactivated calf serum. The PP cells responded well to mitogens, and particularly the responses to a T cell mitogen, concanavalin A (Con A), were at similar levels to those of spleen cells. When the cells were stimulated with alloantigens in mixed lymphocyte reaction, significant response was observed. The PP cells cultured with lipopolysaccharide (LPS) exhibited polyclonal B cell responses (antigen-nonspecific increase in the number of antibody-producing cells) . Furthermore, the levels of anti sheep erythrocytes (SRBC) plaque-forming cells (PFC) in PP cell cultures increased significantly when the PP cells were cultured with SRBC in vitro. However, the PP cells did not show the natural killer (NK) activity. These results showed that the PP cells obtained by the physical method described here contained functionable T and B lymphocytes and accessory cells.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124956108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.6.2_55
Charuay Ekataksin, Y. Inagaki, M. Higaki, R. Nakaya
The fecal bacterial flora of three healthy Thai residents in Japan were determined . Two were short-term or long-term vegetarians and one was a mixed-diet omnivore . The total bacterial counts of all these subjects were significantly lower than those of the average Japanese. The total counts and the numbers of anaerobic bacteria in the vegetarians were constant, whereas a fluctuation between the omnivore's two samplings was observed, accompanied with a decrease in bacteroidaceae , eubacteria, bifidobacteria, enterococci, and veillonellae, and an increase in Clostridium perfringens , lactobacilli, and staphylococci.
{"title":"Fecal Flora of Thai Residents in Japan; Comparison between Vegetarians and an Omnivore","authors":"Charuay Ekataksin, Y. Inagaki, M. Higaki, R. Nakaya","doi":"10.12938/BIFIDUS1982.6.2_55","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.6.2_55","url":null,"abstract":"The fecal bacterial flora of three healthy Thai residents in Japan were determined . Two were short-term or long-term vegetarians and one was a mixed-diet omnivore . The total bacterial counts of all these subjects were significantly lower than those of the average Japanese. The total counts and the numbers of anaerobic bacteria in the vegetarians were constant, whereas a fluctuation between the omnivore's two samplings was observed, accompanied with a decrease in bacteroidaceae , eubacteria, bifidobacteria, enterococci, and veillonellae, and an increase in Clostridium perfringens , lactobacilli, and staphylococci.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127353748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.1.1_51
Jin Said, K. Mochizuki, N. Homma
The affinity of Bifidobacterium (bifidus) to the mucosal epithelial cells of the ileum was studied. It was clarified that the polysaccharide fraction of the bifidus partici pated in the process of affinity. The changes of the intestinal flora of newborn infants were studied. Within two or three months of birth , a predominance of anaerobic bacteria was established, after which gradual changes in the common intestinal flora of the children occurred. Research on the species level of the bifidus in a mother and her baby revealed that soon after birth both mother and baby had the same species but that in the baby, there was a gradual change in species specific to the individual. The time of these displacements coincided with the appearance of antibody production of blood type substance in the newborn infant .
{"title":"Affinity of the Bifidobacterium to Intestinal Mucosal Epithelial Cells","authors":"Jin Said, K. Mochizuki, N. Homma","doi":"10.12938/BIFIDUS1982.1.1_51","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.1.1_51","url":null,"abstract":"The affinity of Bifidobacterium (bifidus) to the mucosal epithelial cells of the ileum was studied. It was clarified that the polysaccharide fraction of the bifidus partici pated in the process of affinity. The changes of the intestinal flora of newborn infants were studied. Within two or three months of birth , a predominance of anaerobic bacteria was established, after which gradual changes in the common intestinal flora of the children occurred. Research on the species level of the bifidus in a mother and her baby revealed that soon after birth both mother and baby had the same species but that in the baby, there was a gradual change in species specific to the individual. The time of these displacements coincided with the appearance of antibody production of blood type substance in the newborn infant .","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125439046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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