Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.13.2_8
H. Hara, Shou-Tou Li, Masakuni Sasaki, T. Maruyama, A. Terada, Y. Ogata, K. Fujita, H. Ishigami, K. Hara, I. Fujimori, T. Mitsuoka
Lactosucrose (4G-B-D-galactosylsucrose) was fermented in vitro by bifidobacteria and lactobacilli, and to a limited degree by the Bacteroides fragilis group, clostridia, eubacteria, and enterobacteriaceae. The effects of dietary lactosucrose on the fecal flora and fecal metabolites were studied in eight healthy volunteers (20-23 years of age) who ingested 3 g of lactosucrose/day for 7 days followed by 6 g of lactosucrose/day for 7 consecutive days. During lactosucrose intake, the counts of bifidobacteria were increased significantly (p< 0.001), whereas the counts of clostridia, including Clostridium perfringens, and bacteroidaceae were decreased significantly (p<0.05) compared with the values before the intake. The total bacterial counts were decreased significantly (p< 0.05) on day 14 during the intake. The frequency of occurrence of lecithinase-negative clostridia was decreased significantly (p<0.05) when compared with the values before and after the intake. No detectable changes occurred in the counts of other organisms throughout the experimental periods. Fecal concentrations of ammonia, sulfide, phenol, ethylphenol, skatol and indole were decreased significantly (p< 0.05) during lactosucrose intake. Acetic acid and lactic acid were increased significantly (p< 0.05) during the intake. Fecal enzyme activity of B-glucuronidase was decreased significantly (p< 0.05) on day 14 of the intake. Serum very low density lipoprotein (VLDL) was increased significantly (p< 0.01) on day 14 during the intake. Mean fecal pH values decreased from 6.3 to 5.9, and mean water content increased 3.6% during the intake. Fecal weight was increased slightly during the intake. The results obtained showed that the effective dose of lactosucrose for all healthy adults is 3 g/day.
乳糖(4g - b - d -半乳糖糖)由双歧杆菌和乳酸菌体外发酵，脆弱拟杆菌群、梭状芽胞杆菌、真细菌和肠杆菌科也有一定程度的体外发酵。在8名健康志愿者(20-23岁)中，研究了膳食蔗糖对粪便菌群和粪便代谢物的影响，他们连续7天每天摄入3g蔗糖，然后连续7天每天摄入6g蔗糖。饲喂乳糖期间，与饲喂前相比，双歧杆菌数量显著增加(p< 0.001)，包括产气荚膜梭菌在内的梭菌数量和拟杆菌科数量显著减少(p<0.05)。饲粮第14天细菌总数显著降低(p< 0.05)。与摄入前后相比，卵磷脂酶阴性梭菌的出现频率显著降低(p<0.05)。在整个实验期间，其他生物的计数没有发生可检测到的变化。饲喂乳糖后，粪便中氨、硫化物、苯酚、乙酚、甲胺醇和吲哚的浓度显著降低(p< 0.05)。采食期间乙酸和乳酸显著升高(p< 0.05)。饲粮第14天粪便中b -葡萄糖醛酸酶活性显著降低(p< 0.05)。饲粮第14天血清极低密度脂蛋白(VLDL)极显著升高(p< 0.01)。平均粪便pH值从6.3降至5.9，平均含水量增加3.6%。进食期间粪便重量略有增加。结果表明，所有健康成人的有效剂量为3 g/d。
{"title":"Effective Dose of Lactosucrose on Fecal Flora and Fecal Metabolites of Humans","authors":"H. Hara, Shou-Tou Li, Masakuni Sasaki, T. Maruyama, A. Terada, Y. Ogata, K. Fujita, H. Ishigami, K. Hara, I. Fujimori, T. Mitsuoka","doi":"10.12938/BIFIDUS1982.13.2_8","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.13.2_8","url":null,"abstract":"Lactosucrose (4G-B-D-galactosylsucrose) was fermented in vitro by bifidobacteria and lactobacilli, and to a limited degree by the Bacteroides fragilis group, clostridia, eubacteria, and enterobacteriaceae. The effects of dietary lactosucrose on the fecal flora and fecal metabolites were studied in eight healthy volunteers (20-23 years of age) who ingested 3 g of lactosucrose/day for 7 days followed by 6 g of lactosucrose/day for 7 consecutive days. During lactosucrose intake, the counts of bifidobacteria were increased significantly (p< 0.001), whereas the counts of clostridia, including Clostridium perfringens, and bacteroidaceae were decreased significantly (p<0.05) compared with the values before the intake. The total bacterial counts were decreased significantly (p< 0.05) on day 14 during the intake. The frequency of occurrence of lecithinase-negative clostridia was decreased significantly (p<0.05) when compared with the values before and after the intake. No detectable changes occurred in the counts of other organisms throughout the experimental periods. Fecal concentrations of ammonia, sulfide, phenol, ethylphenol, skatol and indole were decreased significantly (p< 0.05) during lactosucrose intake. Acetic acid and lactic acid were increased significantly (p< 0.05) during the intake. Fecal enzyme activity of B-glucuronidase was decreased significantly (p< 0.05) on day 14 of the intake. Serum very low density lipoprotein (VLDL) was increased significantly (p< 0.01) on day 14 during the intake. Mean fecal pH values decreased from 6.3 to 5.9, and mean water content increased 3.6% during the intake. Fecal weight was increased slightly during the intake. The results obtained showed that the effective dose of lactosucrose for all healthy adults is 3 g/day.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114811557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.10.2_131
T. Chida, N. Okamura, R. Nakaya, Y. Benno, T. Mitsuoka
The in vitro activity of selected antibiotics were determined for the strains of Bacteroides vulgatus and B. fragilis isolated from the feces and bowel tissue specimens of patients with ulcerative colitis (UC) and from the feces of healthy adults by an agar dilution method. Significant differences in resistance rates to ampicillin, tetracycline, and macrolide-lincosamide were observed between the strains of B. vulgatus, but not B. fragilis, isolated from the patients with UC and those from the healthy adults.
{"title":"Comparison of Antimicrobial Susceptibility of the Bacteroides vulgatus and B. fragilis Strains Isolated from Feces or Bowel Tissue Specimens of Patients with Ulcerative Colitis and Those from Feces of Healthy Adults","authors":"T. Chida, N. Okamura, R. Nakaya, Y. Benno, T. Mitsuoka","doi":"10.12938/BIFIDUS1982.10.2_131","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.10.2_131","url":null,"abstract":"The in vitro activity of selected antibiotics were determined for the strains of Bacteroides vulgatus and B. fragilis isolated from the feces and bowel tissue specimens of patients with ulcerative colitis (UC) and from the feces of healthy adults by an agar dilution method. Significant differences in resistance rates to ampicillin, tetracycline, and macrolide-lincosamide were observed between the strains of B. vulgatus, but not B. fragilis, isolated from the patients with UC and those from the healthy adults.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114174415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.4.1_23
M. Yamashita, M. Hatano, Hajime Nakamura, R. Murakami, M. Matsuo, T. Matsuo, Yasushi Kumon
For the purpose of investigating the effects of Biofermin-R (BF-R) on the bacterial flora, BF-R was administered in combination with antibiotics , and the fecal flora of children treated with antibiotics alone was compared with that of children treated with both BF-R and antibiotics. Three types of effects were investigated: 1) the inhibitory effect on antibiotic-induced changes of the bacterial flora in patients without diarrhea , 2) the bacterial flora-maintaining and normalizing effect in patients with gastrointestinal symptoms, and 3) the process of normalizing in the fecal bacterial flora of mice administered with antibiotics. The results indicated that the concurrent use of BF-R and an antibiotic inhibited the changes of the intestinal flora that usually occur during antibiotic therapy alone, by preventing a decrease in Bifidobacterium, and restored disturbed flora to normal.
为了研究生物铁蛋白- r (BF-R)对细菌菌群的影响，我们将BF-R与抗生素联合使用，并比较单独使用抗生素的儿童与同时使用BF-R和抗生素的儿童的粪便菌群。研究了三种作用:1)抗生素对非腹泻患者细菌菌群变化的抑制作用;2)胃肠道症状患者细菌菌群维持和正常化作用;3)抗生素给药小鼠粪便细菌菌群的正常化过程。结果表明，BF-R与抗生素同时使用，通过防止双歧杆菌的减少，抑制了抗生素单独治疗时肠道菌群的变化，使受干扰的菌群恢复正常。
{"title":"Effects of Biofermin-R Administered in Combination with Antibiotics on the Fecal Flora","authors":"M. Yamashita, M. Hatano, Hajime Nakamura, R. Murakami, M. Matsuo, T. Matsuo, Yasushi Kumon","doi":"10.12938/BIFIDUS1982.4.1_23","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.4.1_23","url":null,"abstract":"For the purpose of investigating the effects of Biofermin-R (BF-R) on the bacterial flora, BF-R was administered in combination with antibiotics , and the fecal flora of children treated with antibiotics alone was compared with that of children treated with both BF-R and antibiotics. Three types of effects were investigated: 1) the inhibitory effect on antibiotic-induced changes of the bacterial flora in patients without diarrhea , 2) the bacterial flora-maintaining and normalizing effect in patients with gastrointestinal symptoms, and 3) the process of normalizing in the fecal bacterial flora of mice administered with antibiotics. The results indicated that the concurrent use of BF-R and an antibiotic inhibited the changes of the intestinal flora that usually occur during antibiotic therapy alone, by preventing a decrease in Bifidobacterium, and restored disturbed flora to normal.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131263807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.10.2_113
D. Hoover, D. B. Hughes
Bifidobacteria have been known and studied throughout the 20th century. The early work originated at the Pasteur Institute. Since that time basic and applied research on bifidobacteria have been done worldwide, with a portion carried out in the U.S. Presently Japan dominates the study and development of bifidobacteria for human use. This article examines some of the possible reasons for the minor role of the U.S. in the study of bifidobacteria and development of bifidobacteria-amended products, with a discussion of future trends in this area.
{"title":"Current Status and Future Trends of Bifidobacteria-related Research and Products in the USA","authors":"D. Hoover, D. B. Hughes","doi":"10.12938/BIFIDUS1982.10.2_113","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.10.2_113","url":null,"abstract":"Bifidobacteria have been known and studied throughout the 20th century. The early work originated at the Pasteur Institute. Since that time basic and applied research on bifidobacteria have been done worldwide, with a portion carried out in the U.S. Presently Japan dominates the study and development of bifidobacteria for human use. This article examines some of the possible reasons for the minor role of the U.S. in the study of bifidobacteria and development of bifidobacteria-amended products, with a discussion of future trends in this area.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129059032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.2.1_17
R. Tanaka, H. Takayama, M. Morotomi, T. Kuroshima, S. Ueyama, Keisuke Matsumoto, A. Kuroda, M. Mutai
We studied the effects of administration of TOS, a new growth factor derived from lactose for Bifidobacterium, and Bifidobacterium breve 4006 on the fecal flora of normal subjects. All of the Bifidobacterium species tested, eight reference strains and B. breve 4006 were capable of fermenting TOS in vitro, while others, 2 Bacteroides strains and 4 Lactobacillus and Enterobacteriaceae strains, showed an appreciable growth among 55 cultures tested. It was evident that TOS is not intestinally absorbed by the recipient subjects, from hydrogen breath test. In vivo, TOS (3g or 10g/day) was observed to promote the growth of both administered B. breve 4006 and resident Bifidobacterium strains. Simultaneous administration of B. breve 4006 and TOS caused the suppression of gram negative anaerobes and aerobes, Bacteroidaceae nd Enterobacteriaceae , and the reduction of fecal ammonia and urinary indican excretion. It is concluded that TOS is a typical bifidus factor.
{"title":"Effects of Administration of TOS and Bifidobacterium breve 4006 on the Human Fecal Flora","authors":"R. Tanaka, H. Takayama, M. Morotomi, T. Kuroshima, S. Ueyama, Keisuke Matsumoto, A. Kuroda, M. Mutai","doi":"10.12938/BIFIDUS1982.2.1_17","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.2.1_17","url":null,"abstract":"We studied the effects of administration of TOS, a new growth factor derived from lactose for Bifidobacterium, and Bifidobacterium breve 4006 on the fecal flora of normal subjects. All of the Bifidobacterium species tested, eight reference strains and B. breve 4006 were capable of fermenting TOS in vitro, while others, 2 Bacteroides strains and 4 Lactobacillus and Enterobacteriaceae strains, showed an appreciable growth among 55 cultures tested. It was evident that TOS is not intestinally absorbed by the recipient subjects, from hydrogen breath test. In vivo, TOS (3g or 10g/day) was observed to promote the growth of both administered B. breve 4006 and resident Bifidobacterium strains. Simultaneous administration of B. breve 4006 and TOS caused the suppression of gram negative anaerobes and aerobes, Bacteroidaceae nd Enterobacteriaceae , and the reduction of fecal ammonia and urinary indican excretion. It is concluded that TOS is a typical bifidus factor.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114720190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.7.1_19
T. Miwatani, M. Kohda, T. Honda
Two important steps are involved in the pathogenesis of bacterial enteric pathogens. All the enteric pathogens, which enter the gastrointestinal tract through the mouth with food or water, colonize a certain part of the intestine. This important step is called colonization (4, 9) . For example, Vibrio cholerae and Vibrio parahaemolyticus colonize the mucosa of the upper jejunum, whereas Shigella colonizes the ileocaecum and colon. This event (colonization) is mediated by the production of specific surface antigens called "colonization factors" and specific receptors for the factors. The reason for the differences between the symptoms produced by V. cholerae O1 and V. parahaemolyticus, both of which colonize a similar region of the small intestine, is that they produce different toxins. Thus the second important step in the pathogenesis of bacterial enteric pathogens is the production of toxins and/or invasion.
{"title":"Pathogenic Mechanisms of Bacterial Enteropathogens","authors":"T. Miwatani, M. Kohda, T. Honda","doi":"10.12938/BIFIDUS1982.7.1_19","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.7.1_19","url":null,"abstract":"Two important steps are involved in the pathogenesis of bacterial enteric pathogens. All the enteric pathogens, which enter the gastrointestinal tract through the mouth with food or water, colonize a certain part of the intestine. This important step is called colonization (4, 9) . For example, Vibrio cholerae and Vibrio parahaemolyticus colonize the mucosa of the upper jejunum, whereas Shigella colonizes the ileocaecum and colon. This event (colonization) is mediated by the production of specific surface antigens called \"colonization factors\" and specific receptors for the factors. The reason for the differences between the symptoms produced by V. cholerae O1 and V. parahaemolyticus, both of which colonize a similar region of the small intestine, is that they produce different toxins. Thus the second important step in the pathogenesis of bacterial enteric pathogens is the production of toxins and/or invasion.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129332709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.6.2_59
Y. Benno, K. Endo, N. Shiragami, K. Sayama, Tomotari Mitsuokai
The effects of four-week raffinose intake (15 g/day) on the fecal microflora and fecal properties were studied in healthy human volunteers. The significantly increasing numbers of Bifidobacterium spp. were observed during the raffinose intake, whereas the numbers of lecithinase-negative Clostridium spp. and bacteroidaceae during the intake were significantly lower than those before and after the intake. The percentage of Bifidobacterium spp. was increased from 11.6-15.5% of the total to 58.2-80.1% of the total during the intake. The fecal pH values during the feeding were lower than those before and after the intake.
{"title":"Effects of Raffinose Intake on Human Fecal Microflora","authors":"Y. Benno, K. Endo, N. Shiragami, K. Sayama, Tomotari Mitsuokai","doi":"10.12938/BIFIDUS1982.6.2_59","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.6.2_59","url":null,"abstract":"The effects of four-week raffinose intake (15 g/day) on the fecal microflora and fecal properties were studied in healthy human volunteers. The significantly increasing numbers of Bifidobacterium spp. were observed during the raffinose intake, whereas the numbers of lecithinase-negative Clostridium spp. and bacteroidaceae during the intake were significantly lower than those before and after the intake. The percentage of Bifidobacterium spp. was increased from 11.6-15.5% of the total to 58.2-80.1% of the total during the intake. The fecal pH values during the feeding were lower than those before and after the intake.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134139018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.11.1_25
T. Yaeshima, T. Fujisawa, T. Mitsuoka
Seventy-six strains of Bifidobacterium adolescentis and phenotypically similar Bifidobacterium species, of which 56 strains were isolated from the feces of human adults in our laboratory and 20 strains were obtained from DSM and ATCC as type strains or reference strains, were studied by carbohydrate fermentation patterns, DNA base compositions and DNA/DNA homologies. On the basis of DNA/DNA homology they were divided into six species: B. adolescentis, B. pseudocatenulatum, B. catenulatum, B. angulatum, B. dentium and B. longum. The strains of B. angulatum and B. dentium were not detected in 56 strains isolated from the feces of human adults. B. catenulatum could be distinguished from other four species, except for B. longum, by the inability to ferment glycogen and mannose. The G+C contents of DNAs of B. pseudocatenulatum and B. catenulatum (57.1•}0.7 mol% and 56.5•}1.0 mol%, respectively) were lower than that of B. adolescentis (59.8•}0.9 mol%). It was difficult to differentiate B. adolescentis biovar b and B. dentium, and B. adolescentis biovar c and B. pseudocatenulatum on the basis of carbohydrate fermentation pattern.
{"title":"Bifidobacterium Species Expressing Phenotypical Similarity to Bifidobacterium adolescentis Isolated from the Feces of Human Adults","authors":"T. Yaeshima, T. Fujisawa, T. Mitsuoka","doi":"10.12938/BIFIDUS1982.11.1_25","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.11.1_25","url":null,"abstract":"Seventy-six strains of Bifidobacterium adolescentis and phenotypically similar Bifidobacterium species, of which 56 strains were isolated from the feces of human adults in our laboratory and 20 strains were obtained from DSM and ATCC as type strains or reference strains, were studied by carbohydrate fermentation patterns, DNA base compositions and DNA/DNA homologies. On the basis of DNA/DNA homology they were divided into six species: B. adolescentis, B. pseudocatenulatum, B. catenulatum, B. angulatum, B. dentium and B. longum. The strains of B. angulatum and B. dentium were not detected in 56 strains isolated from the feces of human adults. B. catenulatum could be distinguished from other four species, except for B. longum, by the inability to ferment glycogen and mannose. The G+C contents of DNAs of B. pseudocatenulatum and B. catenulatum (57.1•}0.7 mol% and 56.5•}1.0 mol%, respectively) were lower than that of B. adolescentis (59.8•}0.9 mol%). It was difficult to differentiate B. adolescentis biovar b and B. dentium, and B. adolescentis biovar c and B. pseudocatenulatum on the basis of carbohydrate fermentation pattern.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129653598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.7.1_56
T. Ikeda, Y. Benno, T. Fujisawa, T. Mitsuoka
{"title":"Phenotypic Characteristics in Distinguishing Clostridium butyricum from Clostridium beijerinckii","authors":"T. Ikeda, Y. Benno, T. Fujisawa, T. Mitsuoka","doi":"10.12938/BIFIDUS1982.7.1_56","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.7.1_56","url":null,"abstract":"","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114275645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.12938/BIFIDUS1982.12.2_57
M. Kawaguchi, Y. Tashiro, T. Adachi, Z. Tamura
Our subject T, who appeared to be a suitable candidate for an assessment of the effects of oligosaccharides, was administrated fructooligosaccharide (FOS) or lactulose and his symptoms, fecal microflora, and composition of rectal gas were investigated. The subject experienced no symptoms in the gut at low dose of FOS. At high dose of FOS, tympanites was observed in the ascending and the transverse colon. By lactulose administration, there were no tympanites, but frequent defecation, rectal gas and loose stool were noted. The number and occupation percentage of fecal bifidobacteria increased by higher doses of FOS (109.1 to 1010.8, 2.9 to 66.2%) and lactulose (108.7 to 1010.5, 0.5 to 25.2%). The composition of rectal gas varied even among samples collected in succession and no clear relationship was observed between the composition of gas and dose. Based on these results, the course of tympanites is discussed.
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