Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.06
R. Shaik
The unidentified virus that causes tomato fever is an infectious illness. The infection's primary signs and symptoms are tomato-shaped blisters that appear all over the body and expand to resemble a tomato, hence the name "Tomato flu." mostly impacts young children under the age of five. A "Hand, Foot, and Mouth illness" is tomato flu. In most situations, the clinical presentation is minimal. The infection is self-limiting and will go away on its own in 7–10 days. In areas where there are outbreaks, the diagnosis is established on the clinical history and physical examination. The etiological agent of this infectious disease, its course of therapy, and its vaccine are still unknown, and this is an important topic of research right now. By repurposing medications and vaccines, which are also synonymously being tried to treat the ailment at the moment, COVID-19 has given us lessons for epidemic preparedness and case management in emergency situations.
{"title":"TOMATO FLU: INSIGHTS AND UNDERSTANDING THE PRESENT INDIAN SCENARIO","authors":"R. Shaik","doi":"10.5455/jcmr.2023.14.02.06","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.06","url":null,"abstract":"The unidentified virus that causes tomato fever is an infectious illness. The infection's primary signs and symptoms are tomato-shaped blisters that appear all over the body and expand to resemble a tomato, hence the name \"Tomato flu.\" mostly impacts young children under the age of five. A \"Hand, Foot, and Mouth illness\" is tomato flu. In most situations, the clinical presentation is minimal. The infection is self-limiting and will go away on its own in 7–10 days. In areas where there are outbreaks, the diagnosis is established on the clinical history and physical examination. The etiological agent of this infectious disease, its course of therapy, and its vaccine are still unknown, and this is an important topic of research right now. By repurposing medications and vaccines, which are also synonymously being tried to treat the ailment at the moment, COVID-19 has given us lessons for epidemic preparedness and case management in emergency situations.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"103 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74948967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.09
R. Mukhamedova, Vladislav Svoikin, Andrei Pishkov, Liubov Lisienkova, Zinira Yapparova, O. Malyugina
The article investigates approaches to reducing the incidence of acute respiratory viral infections among elderly patients. According to the author, in comparison with young people, respiratory viral infection in people over 65 years of age is associated with increased morbidity and mortality. Elderly patients may have severe lower respiratory tract infections, pneumonia, or exacerbation of chronic multimorbid conditions. Additional problems arise due to the fact that elderly patients often do not have fever or respiratory symptoms, but have atypical symptoms, including weakness, confusion and falls. This leads to a failure in diagnosis, an increase in morbidity, the appointment of additional drugs and further nosocomial spread. Currently, it is necessary to introduce sensitive and rapid diagnostics at the place of medical care to detect all viruses and treat infected elderly patients. This will make it easier to understand the true burden of respiratory viruses. To protect the aging immune system, it is now important to combine this with the development of expanded vaccination strategies and new antiviral therapeutics
{"title":"Approaches of Reducing the Incidence of Arvi Among Elderly Patients","authors":"R. Mukhamedova, Vladislav Svoikin, Andrei Pishkov, Liubov Lisienkova, Zinira Yapparova, O. Malyugina","doi":"10.5455/jcmr.2023.14.02.09","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.09","url":null,"abstract":"The article investigates approaches to reducing the incidence of acute respiratory viral infections among elderly patients. According to the author, in comparison with young people, respiratory viral infection in people over 65 years of age is associated with increased morbidity and mortality. Elderly patients may have severe lower respiratory tract infections, pneumonia, or exacerbation of chronic multimorbid conditions. Additional problems arise due to the fact that elderly patients often do not have fever or respiratory symptoms, but have atypical symptoms, including weakness, confusion and falls. This leads to a failure in diagnosis, an increase in morbidity, the appointment of additional drugs and further nosocomial spread. Currently, it is necessary to introduce sensitive and rapid diagnostics at the place of medical care to detect all viruses and treat infected elderly patients. This will make it easier to understand the true burden of respiratory viruses. To protect the aging immune system, it is now important to combine this with the development of expanded vaccination strategies and new antiviral therapeutics","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"1 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72744398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.36
M. Das, Amrit Pegu
Aim: Medicinal plants are widely used as alternative treatment methods for the curing of a wide range of diseases. The current study focuses on the usage of various medicinal plants by the Mising tribe in Gohpur sub-division of Biswanath district, Assam. Methods: An ethnobotanical survey was conducted from April 2021 to August 2021, and data was collected from 25 villages, which are predominantly inhabited by the mising population. A total of 47 informants were interviewed in a face-to-face manner with the help of a readymade questionnaire. Results: A total of 113 medicinal plant species were documented from the study area. which are divided into 102 genera and 56 families. Malvaceae and Poaceae has the most medicinal plants (6 species each), followed by Asteraceae with 5 species, Lamiaceae; Solanaceae; Moraceae; Euphorbiaceae and Zingiberaceae with 4 species each, Fabaceae; Liliaceae; Aracaceae; Apocynaceae; Piperaceae; Combretaceae; Cucurbitaceae; Lauraceae and Caesalpiniaceae with 3 species each. The remaining 10 families have 2 species each, and the remaining 29 families have 1 species each. Most of the reported species were herbs (52%), followed by trees (21%), shrubs (14%), and climbers (10%). Juice preparation (40.70%) and leaves (44%) were the most common methods of preparation of drugs and the most commonly used parts of medicinal plants, respectively. Conclusion: A diverse range of medicinal plants were found in the study area and these plants play a key role in mising people's healthcare system. Some medicinal plants are declining rapidly due to various developmental activities and other environmental effects.
{"title":"An Ethnobotanical Survey Of Medicinal Plants Used By Mising Tribe Of The Gohpur Sub-Division Of Biswanath District, Assam","authors":"M. Das, Amrit Pegu","doi":"10.5455/jcmr.2023.14.02.36","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.36","url":null,"abstract":"Aim: Medicinal plants are widely used as alternative treatment methods for the curing of a wide range of diseases. The current study focuses on the usage of various medicinal plants by the Mising tribe in Gohpur sub-division of Biswanath district, Assam. Methods: An ethnobotanical survey was conducted from April 2021 to August 2021, and data was collected from 25 villages, which are predominantly inhabited by the mising population. A total of 47 informants were interviewed in a face-to-face manner with the help of a readymade questionnaire. Results: A total of 113 medicinal plant species were documented from the study area. which are divided into 102 genera and 56 families. Malvaceae and Poaceae has the most medicinal plants (6 species each), followed by Asteraceae with 5 species, Lamiaceae; Solanaceae; Moraceae; Euphorbiaceae and Zingiberaceae with 4 species each, Fabaceae; Liliaceae; Aracaceae; Apocynaceae; Piperaceae; Combretaceae; Cucurbitaceae; Lauraceae and Caesalpiniaceae with 3 species each. The remaining 10 families have 2 species each, and the remaining 29 families have 1 species each. Most of the reported species were herbs (52%), followed by trees (21%), shrubs (14%), and climbers (10%). Juice preparation (40.70%) and leaves (44%) were the most common methods of preparation of drugs and the most commonly used parts of medicinal plants, respectively. Conclusion: A diverse range of medicinal plants were found in the study area and these plants play a key role in mising people's healthcare system. Some medicinal plants are declining rapidly due to various developmental activities and other environmental effects.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"11 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85958877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The introduction of medical digital technologies can provide better access and flexibility of healthcare for the population. It includes the availability of open information about health, treatment, complications, and recent progress in biomedical research. Nowadays, even in low-income countries, diagnostic and medical services are becoming more accessible. However, many issues related to digital health technologies remain unresolved, including reliability, security, testing, and ethical issues.The penetration of AI currently affects almost all areas of work of medical organizations and government and supervision bodies in the field of healthcare, as well as all major nosological groups. The leading areas of AI application are: medical diagnostics and image analysis, predictive clinical and managerial analytics, medical decision support systems, data analysis of wearable devices, telemedicine, monitoring of patients with chronic non-communicable diseases, virtual assistants, including robot-assisted surgery, decision assistance mental health problems, etc.This article explores the role of interactive technologies in optimizing the patient care process and discusses the prospects and challenges they present for healthcare. In recent years, interactive technologies such as mobile applications, virtual reality, remote medical consultations and electronic health monitoring systems have become increasingly common in medical practice. Digital platforms can help optimize patient diagnosis, counselling and treatment. However, due to the lack of official regulations and recommendations, stakeholders, including private and public organizations, face the problem of adequate verification and testing of new digital health technologies. In this regard, proper scientific research is needed before a digital product is deployed for the health sector.The authors emphasize that interactive technologies have a significant potential for optimizing the process of treating patients in healthcare. They can improve the availability and quality of medical care, as well as increase patient satisfaction.
{"title":"The Role of Interactive Technologies in Optimizing the Process of Patient Treatment: Prospects and Challenges for Health Care","authors":"Nikita Anikin, Anastasiia Dik, Diana Yambrovskaya, Ksenia Mikhaylova, Taras Markvashev, Elena Petrenko","doi":"10.5455/jcmr.2023.14.03.19","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.19","url":null,"abstract":"The introduction of medical digital technologies can provide better access and flexibility of healthcare for the population. It includes the availability of open information about health, treatment, complications, and recent progress in biomedical research. Nowadays, even in low-income countries, diagnostic and medical services are becoming more accessible. However, many issues related to digital health technologies remain unresolved, including reliability, security, testing, and ethical issues.The penetration of AI currently affects almost all areas of work of medical organizations and government and supervision bodies in the field of healthcare, as well as all major nosological groups. The leading areas of AI application are: medical diagnostics and image analysis, predictive clinical and managerial analytics, medical decision support systems, data analysis of wearable devices, telemedicine, monitoring of patients with chronic non-communicable diseases, virtual assistants, including robot-assisted surgery, decision assistance mental health problems, etc.This article explores the role of interactive technologies in optimizing the patient care process and discusses the prospects and challenges they present for healthcare. In recent years, interactive technologies such as mobile applications, virtual reality, remote medical consultations and electronic health monitoring systems have become increasingly common in medical practice. Digital platforms can help optimize patient diagnosis, counselling and treatment. However, due to the lack of official regulations and recommendations, stakeholders, including private and public organizations, face the problem of adequate verification and testing of new digital health technologies. In this regard, proper scientific research is needed before a digital product is deployed for the health sector.The authors emphasize that interactive technologies have a significant potential for optimizing the process of treating patients in healthcare. They can improve the availability and quality of medical care, as well as increase patient satisfaction.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"102 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79411512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.24
J. Ibrahim, K. Esievo, O. Fatokun, O. Adigwe
The purpose of this study is to investigate the knowledge, attitude, and practice of Nigerian health care practitioners regarding the use of herbal medications in the therapy of COVID-19. This was an online survey of Nigerian healthcare practitioners. To assess the level of relationship among research variables, descriptive statistics and chi-square tests were used. A p-value of less than 0.05 was considered statistically significant. Many (77.1%) respondents are aware of claims of the use of herbal medicines for COVID-19, 22.9% of the respondents reported that herbal medicines can be used as cure for COVID-19 while 41.8% believed that herbal medicines can only be used to manage COVID-19 and its symptoms. Most (67.3%) respondents were of the opinion that herbal medicine use for the management of COVID-19 is controversial while 53.3% reported that the use of herbal medicine to manage COVID-19 cannot be substantiated. Majority (79.6%) doctors, (85.4%) nurses and 84.3% (pharmacist) were willing to support research into safety and efficacy of herbal medicines to manage COVID-19. Respondents' observed knowledge of the usage of herbal remedies for COVID-19 could be attributed to the growing awareness in herbal-based products/medicines.
{"title":"Knowledge, Attitude and Practice of Health Care Practitioners in Nigeria Towards the Use of Plants/Herbal Medicines in the Management of COVID-19","authors":"J. Ibrahim, K. Esievo, O. Fatokun, O. Adigwe","doi":"10.5455/jcmr.2023.14.02.24","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.24","url":null,"abstract":"The purpose of this study is to investigate the knowledge, attitude, and practice of Nigerian health care practitioners regarding the use of herbal medications in the therapy of COVID-19. This was an online survey of Nigerian healthcare practitioners. To assess the level of relationship among research variables, descriptive statistics and chi-square tests were used. A p-value of less than 0.05 was considered statistically significant. Many (77.1%) respondents are aware of claims of the use of herbal medicines for COVID-19, 22.9% of the respondents reported that herbal medicines can be used as cure for COVID-19 while 41.8% believed that herbal medicines can only be used to manage COVID-19 and its symptoms. Most (67.3%) respondents were of the opinion that herbal medicine use for the management of COVID-19 is controversial while 53.3% reported that the use of herbal medicine to manage COVID-19 cannot be substantiated. Majority (79.6%) doctors, (85.4%) nurses and 84.3% (pharmacist) were willing to support research into safety and efficacy of herbal medicines to manage COVID-19. Respondents' observed knowledge of the usage of herbal remedies for COVID-19 could be attributed to the growing awareness in herbal-based products/medicines.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"35 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76893003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.24
Bhavana Garapati, S. Varghese, T. Murugan, A. Rajasekar
Gingival recession is one of the most popular periodontal diseases. Aesthetics and hypersensitivity are two major concerns with recession. Although there are multiple treatment options, minimally invasive techniques have recently received much attention due to better patient acceptance and pretty much identical outcomes/results when compared to traditional standard treatment options. Here, we report a case of 34-year-old male patient who presented with the chief complaint of sensitivity to warm and cold in the left upper front tooth region. A 2mm hole was created and a full thickness flap was elevated from the apical side of the tooth towards marginal gingiva, leaving the interdental papilla intact. After relieving the gingiva from beneath, it was sutured to the tooth as an anchorage. Many allogenic materials have been used to replace the space between the flap and bone underneath. The prognosis was fair for this procedure. However, the efficacy of a Novel Volume stabilizing collagen matrix with a modified Pinhole technique is unknown. This report has shown promising results for the treatment of Miller's Class I and II gingival recession.
{"title":"Efficacy of Volume Stabilizing Collagen Matrix in Modified Pinhole Surgical Technique - A Case Report","authors":"Bhavana Garapati, S. Varghese, T. Murugan, A. Rajasekar","doi":"10.5455/jcmr.2023.14.03.24","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.24","url":null,"abstract":"Gingival recession is one of the most popular periodontal diseases. Aesthetics and hypersensitivity are two major concerns with recession. Although there are multiple treatment options, minimally invasive techniques have recently received much attention due to better patient acceptance and pretty much identical outcomes/results when compared to traditional standard treatment options. Here, we report a case of 34-year-old male patient who presented with the chief complaint of sensitivity to warm and cold in the left upper front tooth region. A 2mm hole was created and a full thickness flap was elevated from the apical side of the tooth towards marginal gingiva, leaving the interdental papilla intact. After relieving the gingiva from beneath, it was sutured to the tooth as an anchorage. Many allogenic materials have been used to replace the space between the flap and bone underneath. The prognosis was fair for this procedure. However, the efficacy of a Novel Volume stabilizing collagen matrix with a modified Pinhole technique is unknown. This report has shown promising results for the treatment of Miller's Class I and II gingival recession.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"57 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77677775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.18
Kristina Barykina, Zainab Ismailova, Konstantin Karanov, L. Bizhoeva, E. Turovinina, Alexander Markov
The article discusses the prevention of complications of cardiac pathologies. As the author points out, complications associated with heart disease can be serious and even dangerous. Therefore, it is important to consult a doctor in a timely manner and conduct regular medical examinations in order to prevent or detect possible heart problems early. It is also important to lead a healthy lifestyle, including proper nutrition, regular exercise and smoking cessation. In addition to individual prevention measures, it is necessary to regularly develop and implement State programs for the prevention of cardiovascular diseases, which include educational campaigns and subsidizing activities to improve overall health, such as subsidies for physical activity and anti-obesity programs. Large-scale campaigns are also needed to reduce the level of smoking and control alcohol consumption. Keywords: cardiological pathologies, complications, liver
{"title":"Prevention of Complications of Cardiac Pathologies","authors":"Kristina Barykina, Zainab Ismailova, Konstantin Karanov, L. Bizhoeva, E. Turovinina, Alexander Markov","doi":"10.5455/jcmr.2023.14.02.18","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.18","url":null,"abstract":"The article discusses the prevention of complications of cardiac pathologies. As the author points out, complications associated with heart disease can be serious and even dangerous. Therefore, it is important to consult a doctor in a timely manner and conduct regular medical examinations in order to prevent or detect possible heart problems early. It is also important to lead a healthy lifestyle, including proper nutrition, regular exercise and smoking cessation. In addition to individual prevention measures, it is necessary to regularly develop and implement State programs for the prevention of cardiovascular diseases, which include educational campaigns and subsidizing activities to improve overall health, such as subsidies for physical activity and anti-obesity programs. Large-scale campaigns are also needed to reduce the level of smoking and control alcohol consumption. Keywords: cardiological pathologies, complications, liver","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"42 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89522275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.22
H. Abed, H. Sadek, Abdullah Aloufi, Mohammad Bamunif, A. Demyati, Deema Altuwairgi, Khalid A Aljohani
The World Health Organization explained myelodysplastic syndromes as clonal hematopoietic disorders characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. Myelodysplastic syndromes have a high probability of transformation into acute myeloid leukemia. Dental care professionals should have a basic understanding of myelodysplastic syndromes to help support patients and deliver safe dental treatment.
{"title":"Myelodysplastic syndromes and acute myeloid leukemia: Medical management and dental considerations","authors":"H. Abed, H. Sadek, Abdullah Aloufi, Mohammad Bamunif, A. Demyati, Deema Altuwairgi, Khalid A Aljohani","doi":"10.5455/jcmr.2023.14.03.22","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.22","url":null,"abstract":"The World Health Organization explained myelodysplastic syndromes as clonal hematopoietic disorders characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. Myelodysplastic syndromes have a high probability of transformation into acute myeloid leukemia. Dental care professionals should have a basic understanding of myelodysplastic syndromes to help support patients and deliver safe dental treatment.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"83 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87376670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.15
B. Jamal
Introduction: The temporomandibular disorder (TMD) is a common pathological entity and is found in 31% of the adult population. Different minimally invasive techniques, such as the injection of diverse substances into the joint, arthrocentesis have exhibited good clinical results and such modalities would be considered either for severe TMDs or after the failure of conservative treatments. Several studies endorsed intra-articular injections of platelet- rich plasma (PRP) as an effective procedure to decrease TMD tenderness. The primary aim of this study is to assess the effectiveness of a single PRP injection in terms of reducing pain, and improving mandibular motion in patients affected by internal derangement of the TMJ. Materials & Methods: The study consisted of 10 patients who reported to the oral and maxillofacial surgery clinic with painful dysfunction of the temporomandibular joint who received a single injection of PRP in the TMJ. Variables measured including pain score and mouth opening were assessed preoperatively and postoperativel. SPSS 24.0 was used for data management and statistical analysis. The level of significance was set at 0.05 for all statistical tests using chi-square. Results:The group of 10 patients consisted of 9 women and 1 man. The age of the participants ranged from 27 to 75 years, and a median age of 45.5. Upon the follow up visit within 1-3 months: 7/10 patients showed a significant reduction of the pain intensity (more than 50% reduction of pain intensity), 2/10 patients showed a partial resolution of the symptoms with minimal reduction of pain and one patient showed no improvement in either pain or mouth opening and subsequently underwent arthrocentesis. The PRP injections were successful in decreasing pain intensity scores to below 5 in most cases. A Chi-squared test was performed to test for an association between the PRP injections and pain intensity score and the outcome supports the conclusion that there is a strong correlation between the PRP injection and pain and that it is statistically significant. Conclusions:TMD symptoms and movement limitations disrupt everyday life and in cases with severe illness, studies showed that the conservative treatment measures lead to insignificant or low improvement in quality of life. For this reason, a fast acting and effective method of reducing pain and movement limitations is essential and our study findings support the role of PRP injections. It exhibited a very strong negative relationship, which indicates that the PRP injection and pain scores are inversely related.
{"title":"Does Single Intra-Articular Plasma-Rich Plasma (PRP) Injection for Temporomandibular Joint (TMJ) Internal Derangement Relieve Joint Pain?","authors":"B. Jamal","doi":"10.5455/jcmr.2023.14.02.15","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.15","url":null,"abstract":"Introduction: The temporomandibular disorder (TMD) is a common pathological entity and is found in 31% of the adult population. Different minimally invasive techniques, such as the injection of diverse substances into the joint, arthrocentesis have exhibited good clinical results and such modalities would be considered either for severe TMDs or after the failure of conservative treatments. Several studies endorsed intra-articular injections of platelet- rich plasma (PRP) as an effective procedure to decrease TMD tenderness. The primary aim of this study is to assess the effectiveness of a single PRP injection in terms of reducing pain, and improving mandibular motion in patients affected by internal derangement of the TMJ. Materials & Methods: The study consisted of 10 patients who reported to the oral and maxillofacial surgery clinic with painful dysfunction of the temporomandibular joint who received a single injection of PRP in the TMJ. Variables measured including pain score and mouth opening were assessed preoperatively and postoperativel. SPSS 24.0 was used for data management and statistical analysis. The level of significance was set at 0.05 for all statistical tests using chi-square. Results:The group of 10 patients consisted of 9 women and 1 man. The age of the participants ranged from 27 to 75 years, and a median age of 45.5. Upon the follow up visit within 1-3 months: 7/10 patients showed a significant reduction of the pain intensity (more than 50% reduction of pain intensity), 2/10 patients showed a partial resolution of the symptoms with minimal reduction of pain and one patient showed no improvement in either pain or mouth opening and subsequently underwent arthrocentesis. The PRP injections were successful in decreasing pain intensity scores to below 5 in most cases. A Chi-squared test was performed to test for an association between the PRP injections and pain intensity score and the outcome supports the conclusion that there is a strong correlation between the PRP injection and pain and that it is statistically significant. Conclusions:TMD symptoms and movement limitations disrupt everyday life and in cases with severe illness, studies showed that the conservative treatment measures lead to insignificant or low improvement in quality of life. For this reason, a fast acting and effective method of reducing pain and movement limitations is essential and our study findings support the role of PRP injections. It exhibited a very strong negative relationship, which indicates that the PRP injection and pain scores are inversely related.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"31 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73654153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.11
S. Abidin, S. Makpol, N. Ahmad, N. Muhamad, W. Yap
Background/Aims: Dengue virus (DENV) spreads widely in many tropical and sub-tropical countries by Aedes sp. In recent decades, dengue has been alarmingly on the rise and affects approximately half of the world population. The current dengue treatments are still mainly supportive without any approved vaccines or effective anti-dengue drugs. This leads to an urgency to seek alternative solutions in reducing dengue morbidity and mortality. Methods: A total of 94 articles describing in vitro and in vivo studies were screened and selected through curated databases. The selected articles underpinned the potentials of natural products as alternative anti-dengue compounds. Results: Those compounds have been employed as larvicide, mosquitocide, mosquito repellents, agents in sticky traps and non-specific interventions for dengue. In this review, their direct and indirect effects on dengue virus replication and dengue diseases were deliberated. Inteestingly, the majority of them demonstrated remarkable anti-inflammatory effects on dengue diseases. Several phytochemical contents such as luteolin, coumarins and geraniin were shown to inhibit DENV replication in vitro. Conclusion: Natural product-based anti-dengue agents are believed to be less costly, easy to derive, biologically effective and less toxic. This review, therefore, aims to provide current updates and insights on the benefits of natural products in preventing, managing and treating dengue.
{"title":"A Review on Unleashing the Potentials of Natural Products in Managing Dengue","authors":"S. Abidin, S. Makpol, N. Ahmad, N. Muhamad, W. Yap","doi":"10.5455/jcmr.2023.14.02.11","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.11","url":null,"abstract":"Background/Aims: Dengue virus (DENV) spreads widely in many tropical and sub-tropical countries by Aedes sp. In recent decades, dengue has been alarmingly on the rise and affects approximately half of the world population. The current dengue treatments are still mainly supportive without any approved vaccines or effective anti-dengue drugs. This leads to an urgency to seek alternative solutions in reducing dengue morbidity and mortality. Methods: A total of 94 articles describing in vitro and in vivo studies were screened and selected through curated databases. The selected articles underpinned the potentials of natural products as alternative anti-dengue compounds. Results: Those compounds have been employed as larvicide, mosquitocide, mosquito repellents, agents in sticky traps and non-specific interventions for dengue. In this review, their direct and indirect effects on dengue virus replication and dengue diseases were deliberated. Inteestingly, the majority of them demonstrated remarkable anti-inflammatory effects on dengue diseases. Several phytochemical contents such as luteolin, coumarins and geraniin were shown to inhibit DENV replication in vitro. Conclusion: Natural product-based anti-dengue agents are believed to be less costly, easy to derive, biologically effective and less toxic. This review, therefore, aims to provide current updates and insights on the benefits of natural products in preventing, managing and treating dengue.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"7 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75979863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}