Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.06
Khyadi Khabrieva, Soltanat Utegenova, A. Polyakov, Zalina Dogaeva, Timur Rustamovich Imamutdinov, Alexander Markov
This work includes consideration of neurological consequences of acute respiratory viral infection (ARVI), such as meningitis, encephalitis, headache, sleep disorders and mental disorders. The authors are based on existing studies showing that ARVI can cause inflammatory processes in the nervous system and lead to long-term health consequences. The article also discusses methods of diagnosis and treatment of neurological manifestations of ARVI. The research results may be useful for doctors treating patients with acute respiratory viral infections, as well as for people who want to understand the possible consequences of this disease. In addition, the authors note that the neurological consequences of ARVI can be especially dangerous for certain groups of patients, such as children, the elderly and people with concomitant diseases. Therefore, it is important to pay attention to the neurological symptoms of ARVI and to carry out timely diagnosis and treatment. The paper also notes that possible causes of neurological manifestations of ARVI may be not only viruses, but also immune mechanisms, as well as other factors such as stress and lack of physical activity during the disease. In general, the article provides an overview of the neurological consequences of ARVI, indicating their severity and the need for additional research in this area. This information can be useful both for doctors and for the general public, helping to understand the importance of prevention and timely treatment of acute respiratory viral infections.
{"title":"Neurological Consequences of Arvi","authors":"Khyadi Khabrieva, Soltanat Utegenova, A. Polyakov, Zalina Dogaeva, Timur Rustamovich\u0000Imamutdinov, Alexander Markov","doi":"10.5455/jcmr.2023.14.03.06","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.06","url":null,"abstract":"This work includes consideration of neurological consequences of acute respiratory viral infection (ARVI), such as meningitis, encephalitis, headache, sleep disorders and mental disorders. The authors are based on existing studies showing that ARVI can cause inflammatory processes in the nervous system and lead to long-term health consequences. The article also discusses methods of diagnosis and treatment of neurological manifestations of ARVI. The research results may be useful for doctors treating patients with acute respiratory viral infections, as well as for people who want to understand the possible consequences of this disease. In addition, the authors note that the neurological consequences of ARVI can be especially dangerous for certain groups of patients, such as children, the elderly and people with concomitant diseases. Therefore, it is important to pay attention to the neurological symptoms of ARVI and to carry out timely diagnosis and treatment. The paper also notes that possible causes of neurological manifestations of ARVI may be not only viruses, but also immune mechanisms, as well as other factors such as stress and lack of physical activity during the disease. In general, the article provides an overview of the neurological consequences of ARVI, indicating their severity and the need for additional research in this area. This information can be useful both for doctors and for the general public, helping to understand the importance of prevention and timely treatment of acute respiratory viral infections.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80685430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.31
N. Qusty, Anas Sarhan, Hassan Alsuhabi, Ali A Alsyed, Abdullah A Alrashdi, Mohammed A. Alessa, Haitham H Alzubaidi, Musleh Alzubaidi, Majed S. Almutairi, Ebrahem R Alsohabi, M. Taha
Background: Irritable bowel syndrome (IBS) is the commonest functional gastrointestinal disorder with worldwide prevalence 11.2%, IBS characterized by recurrent colicky or cramping abdominal pain and altered bowel habit. Methods: A cross sectional study was conducted among AL Qunfudhah population with total 1003 of participants who were asked to complete questionnaires. Results: 28.9% were affected with IBS, this study shows higher predominance in females than males, The most common symptoms among our participants were bloating 37.1%, abdominal pain 26.8% and constipation 20.4%.24.4% were suffering from constipation or diarrhea in the morning and these symptoms affected by spicy food and fried food. Conclusion: Based on our findings, the predominance of IBS among females was higher. Bloating and abdominal pain were the commonest symptoms. Anxiety and depression affect IBS symptoms significantly. Our study emphasizes the correlation between certain foods and IBS symptoms. High fiber diet and low carbohydrate diet will improve the IBS symptoms.
{"title":"Efficiency of life style change in IBS in Alqunfudah governate and its villages","authors":"N. Qusty, Anas Sarhan, Hassan Alsuhabi, Ali A Alsyed, Abdullah A Alrashdi, Mohammed A. Alessa, Haitham H Alzubaidi, Musleh Alzubaidi, Majed S. Almutairi, Ebrahem R Alsohabi, M. Taha","doi":"10.5455/jcmr.2023.14.03.31","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.31","url":null,"abstract":"Background: Irritable bowel syndrome (IBS) is the commonest functional gastrointestinal disorder with worldwide prevalence 11.2%, IBS characterized by recurrent colicky or cramping abdominal pain and altered bowel habit. Methods: A cross sectional study was conducted among AL Qunfudhah population with total 1003 of participants who were asked to complete questionnaires. Results: 28.9% were affected with IBS, this study shows higher predominance in females than males, The most common symptoms among our participants were bloating 37.1%, abdominal pain 26.8% and constipation 20.4%.24.4% were suffering from constipation or diarrhea in the morning and these symptoms affected by spicy food and fried food. Conclusion: Based on our findings, the predominance of IBS among females was higher. Bloating and abdominal pain were the commonest symptoms. Anxiety and depression affect IBS symptoms significantly. Our study emphasizes the correlation between certain foods and IBS symptoms. High fiber diet and low carbohydrate diet will improve the IBS symptoms.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88440166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.11
Andronik Karapetov, I. Lysenko, Aglaya Kazumova, Ilmira Zakirova, K. Kuzmina, Anastasia Islivanova
This article examines the role of physical activity and sports in the prevention and treatment of chronic diseases based on modern scientific data and practical recommendations. The paper describes the mechanisms of the impact of physical activity on the body, including the improvement of metabolism and functions of the cardiovascular system, as well as the prevention and treatment of diseases such as obesity, diabetes, hypertension, heart and vascular diseases, depression and others.The study provides an overview of the results of many studies demonstrating that physical activity and sport have significant therapeutic potential for patients with chronic diseases. The article also provides practical recommendations on the choice of optimal types of physical activity and sports, the frequency and duration of classes, depending on the state of health, age and other factors.It is also noted that physical exercises should be individualized and aimed at achieving specific goals for each patient. At the same time, it is important to take into account the peculiarities of health and age, as well as to observe safety measures and monitor loads.One of the main conclusions of the article is the fact that physical activity and sport not only prevent the development of many chronic diseases, but also can improve the quality of life of patients, as well as reduce the risk of mortality from cardiovascular diseases.Thus, the study highlights the importance of regular physical exercise for the prevention and treatment of chronic diseases, and also recommends that doctors integrate this approach into their practice.
{"title":"The Role Of Physical Activity And Sports In The Prevention And Treatment Of Chronic Diseases: Modern Scientific Data And Practical\u0000Recommendations","authors":"Andronik Karapetov, I. Lysenko, Aglaya Kazumova, Ilmira Zakirova, K. Kuzmina, Anastasia Islivanova","doi":"10.5455/jcmr.2023.14.03.11","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.11","url":null,"abstract":"This article examines the role of physical activity and sports in the prevention and treatment of chronic diseases based on modern scientific data and practical recommendations. The paper describes the mechanisms of the impact of physical activity on the body, including the improvement of metabolism and functions of the cardiovascular system, as well as the prevention and treatment of diseases such as obesity, diabetes, hypertension, heart and vascular diseases, depression and others.The study provides an overview of the results of many studies demonstrating that physical activity and sport have significant therapeutic potential for patients with chronic diseases. The article also provides practical recommendations on the choice of optimal types of physical activity and sports, the frequency and duration of classes, depending on the state of health, age and other factors.It is also noted that physical exercises should be individualized and aimed at achieving specific goals for each patient. At the same time, it is important to take into account the peculiarities of health and age, as well as to observe safety measures and monitor loads.One of the main conclusions of the article is the fact that physical activity and sport not only prevent the development of many chronic diseases, but also can improve the quality of life of patients, as well as reduce the risk of mortality from cardiovascular diseases.Thus, the study highlights the importance of regular physical exercise for the prevention and treatment of chronic diseases, and also recommends that doctors integrate this approach into their practice.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91198028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.27
Polina Terenteva, M. Fomina, Olesya Zimoglyad, Elizaveta Korotkaya, Elena Mikhailova, Yuriy Pyzhurin
The article examines the features of prevention of cardiovascular diseases in young people. The author notes that cardiovascular diseases are among the most common diseases worldwide and cause a significant number of deaths and disabilities. According to the World Health Organization (WHO), cardiovascular diseases are the leading cause of death in the world, and they account for about 31% of all deaths. Many of the risk factors for the development of cardiovascular diseases in young patients can be prevented by preventive measures, such as proper nutrition, moderate physical activity, quitting smoking and alcohol consumption, weight and blood pressure control, as well as regular medical examinations. In addition, the popularization of a healthy lifestyle, carried out through lectures, presentations, etc., plays an important role.
{"title":"Prevention of Cardiovascular Diseases in Young People","authors":"Polina Terenteva, M. Fomina, Olesya Zimoglyad, Elizaveta Korotkaya, Elena Mikhailova, Yuriy Pyzhurin","doi":"10.5455/jcmr.2023.14.02.27","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.27","url":null,"abstract":"The article examines the features of prevention of cardiovascular diseases in young people. The author notes that cardiovascular diseases are among the most common diseases worldwide and cause a significant number of deaths and disabilities. According to the World Health Organization (WHO), cardiovascular diseases are the leading cause of death in the world, and they account for about 31% of all deaths. Many of the risk factors for the development of cardiovascular diseases in young patients can be prevented by preventive measures, such as proper nutrition, moderate physical activity, quitting smoking and alcohol consumption, weight and blood pressure control, as well as regular medical examinations. In addition, the popularization of a healthy lifestyle, carried out through lectures, presentations, etc., plays an important role.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88983705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.33
M. Alqahtani
Objective: The present study aims to explore the impact of a multimodal mental practice approach on enhancing upper extremity function in chronic stroke patients. Specifically, we seek to investigate the potential benefits of incorporating MMP into the existing rehabilitation protocols for stroke survivors and assess its effectiveness in improving motor outcomes. Methods: The study utilized a randomized controlled trial design with chronic stroke patients who experienced upper extremity impairments. The participants were provided multimodal physical practice, multimodal mental practice, and blended multimodal practice regimen for three months. Results: The ANOVA analysis revealed a significant difference among the groups for the MMPG measure, indicating that the Blended Multimodal Practice Group (BMPG) performed significantly better compared to the Multimodal Physical Practice Group (MPPG) and the Multimodal Mental Practice Group (MMPG). Conclusion: The findings of this study suggest that incorporating multimodal mental practice approaches into stroke rehabilitation programs can enhance upper extremity function in chronic stroke patients.
{"title":"Enhancing Upper Extremity Function in Chronic Stroke Patients: Exploration of the Impact of Multimodal Mental Practice Approach","authors":"M. Alqahtani","doi":"10.5455/jcmr.2023.14.03.33","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.33","url":null,"abstract":"Objective: The present study aims to explore the impact of a multimodal mental practice approach on enhancing upper extremity function in chronic stroke patients. Specifically, we seek to investigate the potential benefits of incorporating MMP into the existing rehabilitation protocols for stroke survivors and assess its effectiveness in improving motor outcomes. Methods: The study utilized a randomized controlled trial design with chronic stroke patients who experienced upper extremity impairments. The participants were provided multimodal physical practice, multimodal mental practice, and blended multimodal practice regimen for three months. Results: The ANOVA analysis revealed a significant difference among the groups for the MMPG measure, indicating that the Blended Multimodal Practice Group (BMPG) performed significantly better compared to the Multimodal Physical Practice Group (MPPG) and the Multimodal Mental Practice Group (MMPG). Conclusion: The findings of this study suggest that incorporating multimodal mental practice approaches into stroke rehabilitation programs can enhance upper extremity function in chronic stroke patients.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86769187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.01.03
H. Ali, N. Rajab
The main aim of this research work was the development and evaluation of polymeric nanoparticle for the bioavailability improvement of Ebastine (EBT) to treat allergic condition. EBT is a piperidine derivative that binds preferentially to peripheral H1 receptors and is a long-acting, non-sedating second-generation histamine receptor antagonist. It is practically insoluble in water (class II, according to BCS). This work aims to formulate and adjust Ebastine polymeric nanoparticles to improve the EBT solubility as well as dissolution rate. For the synthesis of PNPs, the solvent evaporation technique was used, and three different types of stabilizer that used (HPMC E5, Soluplus, tween 80). The particle size analysis indicated that the optimized formula EBT 9 had a reduced nanoparticulate size of 42 nm, with a 90 percent increase in in-vitro dissolution profile compared to 17 percent for the comparison Ebastine powder in 0.1 N HCl media (pH 1.2). As a result, polymeric nanoparticles formulation of weakly water soluble EBS greatly improved the drug's dissolving rate and increased its solubility.
{"title":"Polymeric nanoparticle of Ebastine: Formulation, Characterization and in vitro Evaluation","authors":"H. Ali, N. Rajab","doi":"10.5455/jcmr.2023.14.01.03","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.03","url":null,"abstract":"The main aim of this research work was the development and evaluation of polymeric nanoparticle for the bioavailability improvement of Ebastine (EBT) to treat allergic condition. EBT is a piperidine derivative that binds preferentially to peripheral H1 receptors and is a long-acting, non-sedating second-generation histamine receptor antagonist. It is practically insoluble in water (class II, according to BCS). This work aims to formulate and adjust Ebastine polymeric nanoparticles to improve the EBT solubility as well as dissolution rate. For the synthesis of PNPs, the solvent evaporation technique was used, and three different types of stabilizer that used (HPMC E5, Soluplus, tween 80). The particle size analysis indicated that the optimized formula EBT 9 had a reduced nanoparticulate size of 42 nm, with a 90 percent increase in in-vitro dissolution profile compared to 17 percent for the comparison Ebastine powder in 0.1 N HCl media (pH 1.2). As a result, polymeric nanoparticles formulation of weakly water soluble EBS greatly improved the drug's dissolving rate and increased its solubility.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82348736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.11
S. Abidin, S. Makpol, N. Ahmad, N. Muhamad, W. Yap
Background/Aims: Dengue virus (DENV) spreads widely in many tropical and sub-tropical countries by Aedes sp. In recent decades, dengue has been alarmingly on the rise and affects approximately half of the world population. The current dengue treatments are still mainly supportive without any approved vaccines or effective anti-dengue drugs. This leads to an urgency to seek alternative solutions in reducing dengue morbidity and mortality. Methods: A total of 94 articles describing in vitro and in vivo studies were screened and selected through curated databases. The selected articles underpinned the potentials of natural products as alternative anti-dengue compounds. Results: Those compounds have been employed as larvicide, mosquitocide, mosquito repellents, agents in sticky traps and non-specific interventions for dengue. In this review, their direct and indirect effects on dengue virus replication and dengue diseases were deliberated. Inteestingly, the majority of them demonstrated remarkable anti-inflammatory effects on dengue diseases. Several phytochemical contents such as luteolin, coumarins and geraniin were shown to inhibit DENV replication in vitro. Conclusion: Natural product-based anti-dengue agents are believed to be less costly, easy to derive, biologically effective and less toxic. This review, therefore, aims to provide current updates and insights on the benefits of natural products in preventing, managing and treating dengue.
{"title":"A Review on Unleashing the Potentials of Natural Products in Managing Dengue","authors":"S. Abidin, S. Makpol, N. Ahmad, N. Muhamad, W. Yap","doi":"10.5455/jcmr.2023.14.02.11","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.11","url":null,"abstract":"Background/Aims: Dengue virus (DENV) spreads widely in many tropical and sub-tropical countries by Aedes sp. In recent decades, dengue has been alarmingly on the rise and affects approximately half of the world population. The current dengue treatments are still mainly supportive without any approved vaccines or effective anti-dengue drugs. This leads to an urgency to seek alternative solutions in reducing dengue morbidity and mortality. Methods: A total of 94 articles describing in vitro and in vivo studies were screened and selected through curated databases. The selected articles underpinned the potentials of natural products as alternative anti-dengue compounds. Results: Those compounds have been employed as larvicide, mosquitocide, mosquito repellents, agents in sticky traps and non-specific interventions for dengue. In this review, their direct and indirect effects on dengue virus replication and dengue diseases were deliberated. Inteestingly, the majority of them demonstrated remarkable anti-inflammatory effects on dengue diseases. Several phytochemical contents such as luteolin, coumarins and geraniin were shown to inhibit DENV replication in vitro. Conclusion: Natural product-based anti-dengue agents are believed to be less costly, easy to derive, biologically effective and less toxic. This review, therefore, aims to provide current updates and insights on the benefits of natural products in preventing, managing and treating dengue.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75979863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.01.08
Fahad Aljarboa, Saleh Almanea, Abdullah Aljarboa, Tala Almanea, Bader Aldebasi
Objective was assess the knowledge of the adult women with regards to the benefits of breastfeeding at Prince Bader Housing. This study was a cross-sectional survey targeting mothers visiting primary health care clinics. Nearly 200 single-page questionnaires with 20 questions were distributed to visiting mothers at the well-baby clinics. Sampling was convenient and randomness was assumed by visit sequence, on a "first-come-first-serve" basis, and those who agreed to participate. Mothers visiting the O.B clinic or visiting the Pediatrician and Well-Baby Clinic within the PHC centers for immunization of their children (under 2 years of age) SPSS was used for data analysis. The total subjects in this study were 188, the average age of the participants was 32.6 years with a standard deviation of 32, the youngest age of the participant was 22 years and oldest age was 46 years and the average family size was 1.5 (roughly 2 children). A substantial majority of mothers agreed that breast milk is better than any formula milk. More than three-fourths of the mothers responded that Exclusive breastfeeding should be given. The majority of mothers can identify the colostrum in breast milk, majority of mothers believed that breastfeeding will protect their baby from specific diseases.In this study, more than two-thirds of the mothers answered questions in a manner that indicates they are well educated about the benefit of breastfeeding. This points towards the implementation of a good educational program for mothers by healthcare providers.
{"title":"Assessment on Knowledge of Adult Women with Regards to Benefits of Breastfeeding at Prince Bader Housing","authors":"Fahad Aljarboa, Saleh Almanea, Abdullah Aljarboa, Tala Almanea, Bader Aldebasi","doi":"10.5455/jcmr.2023.14.01.08","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.08","url":null,"abstract":"Objective was assess the knowledge of the adult women with regards to the benefits of breastfeeding at Prince Bader Housing. This study was a cross-sectional survey targeting mothers visiting primary health care clinics. Nearly 200 single-page questionnaires with 20 questions were distributed to visiting mothers at the well-baby clinics. Sampling was convenient and randomness was assumed by visit sequence, on a \"first-come-first-serve\" basis, and those who agreed to participate. Mothers visiting the O.B clinic or visiting the Pediatrician and Well-Baby Clinic within the PHC centers for immunization of their children (under 2 years of age) SPSS was used for data analysis. The total subjects in this study were 188, the average age of the participants was 32.6 years with a standard deviation of 32, the youngest age of the participant was 22 years and oldest age was 46 years and the average family size was 1.5 (roughly 2 children). A substantial majority of mothers agreed that breast milk is better than any formula milk. More than three-fourths of the mothers responded that Exclusive breastfeeding should be given. The majority of mothers can identify the colostrum in breast milk, majority of mothers believed that breastfeeding will protect their baby from specific diseases.In this study, more than two-thirds of the mothers answered questions in a manner that indicates they are well educated about the benefit of breastfeeding. This points towards the implementation of a good educational program for mothers by healthcare providers.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76231669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.15
B. Jamal
Introduction: The temporomandibular disorder (TMD) is a common pathological entity and is found in 31% of the adult population. Different minimally invasive techniques, such as the injection of diverse substances into the joint, arthrocentesis have exhibited good clinical results and such modalities would be considered either for severe TMDs or after the failure of conservative treatments. Several studies endorsed intra-articular injections of platelet- rich plasma (PRP) as an effective procedure to decrease TMD tenderness. The primary aim of this study is to assess the effectiveness of a single PRP injection in terms of reducing pain, and improving mandibular motion in patients affected by internal derangement of the TMJ. Materials & Methods: The study consisted of 10 patients who reported to the oral and maxillofacial surgery clinic with painful dysfunction of the temporomandibular joint who received a single injection of PRP in the TMJ. Variables measured including pain score and mouth opening were assessed preoperatively and postoperativel. SPSS 24.0 was used for data management and statistical analysis. The level of significance was set at 0.05 for all statistical tests using chi-square. Results:The group of 10 patients consisted of 9 women and 1 man. The age of the participants ranged from 27 to 75 years, and a median age of 45.5. Upon the follow up visit within 1-3 months: 7/10 patients showed a significant reduction of the pain intensity (more than 50% reduction of pain intensity), 2/10 patients showed a partial resolution of the symptoms with minimal reduction of pain and one patient showed no improvement in either pain or mouth opening and subsequently underwent arthrocentesis. The PRP injections were successful in decreasing pain intensity scores to below 5 in most cases. A Chi-squared test was performed to test for an association between the PRP injections and pain intensity score and the outcome supports the conclusion that there is a strong correlation between the PRP injection and pain and that it is statistically significant. Conclusions:TMD symptoms and movement limitations disrupt everyday life and in cases with severe illness, studies showed that the conservative treatment measures lead to insignificant or low improvement in quality of life. For this reason, a fast acting and effective method of reducing pain and movement limitations is essential and our study findings support the role of PRP injections. It exhibited a very strong negative relationship, which indicates that the PRP injection and pain scores are inversely related.
{"title":"Does Single Intra-Articular Plasma-Rich Plasma (PRP) Injection for Temporomandibular Joint (TMJ) Internal Derangement Relieve Joint Pain?","authors":"B. Jamal","doi":"10.5455/jcmr.2023.14.02.15","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.15","url":null,"abstract":"Introduction: The temporomandibular disorder (TMD) is a common pathological entity and is found in 31% of the adult population. Different minimally invasive techniques, such as the injection of diverse substances into the joint, arthrocentesis have exhibited good clinical results and such modalities would be considered either for severe TMDs or after the failure of conservative treatments. Several studies endorsed intra-articular injections of platelet- rich plasma (PRP) as an effective procedure to decrease TMD tenderness. The primary aim of this study is to assess the effectiveness of a single PRP injection in terms of reducing pain, and improving mandibular motion in patients affected by internal derangement of the TMJ. Materials & Methods: The study consisted of 10 patients who reported to the oral and maxillofacial surgery clinic with painful dysfunction of the temporomandibular joint who received a single injection of PRP in the TMJ. Variables measured including pain score and mouth opening were assessed preoperatively and postoperativel. SPSS 24.0 was used for data management and statistical analysis. The level of significance was set at 0.05 for all statistical tests using chi-square. Results:The group of 10 patients consisted of 9 women and 1 man. The age of the participants ranged from 27 to 75 years, and a median age of 45.5. Upon the follow up visit within 1-3 months: 7/10 patients showed a significant reduction of the pain intensity (more than 50% reduction of pain intensity), 2/10 patients showed a partial resolution of the symptoms with minimal reduction of pain and one patient showed no improvement in either pain or mouth opening and subsequently underwent arthrocentesis. The PRP injections were successful in decreasing pain intensity scores to below 5 in most cases. A Chi-squared test was performed to test for an association between the PRP injections and pain intensity score and the outcome supports the conclusion that there is a strong correlation between the PRP injection and pain and that it is statistically significant. Conclusions:TMD symptoms and movement limitations disrupt everyday life and in cases with severe illness, studies showed that the conservative treatment measures lead to insignificant or low improvement in quality of life. For this reason, a fast acting and effective method of reducing pain and movement limitations is essential and our study findings support the role of PRP injections. It exhibited a very strong negative relationship, which indicates that the PRP injection and pain scores are inversely related.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73654153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.23
Bhavana Garapati, S. Varghese, V. J, Karthikeyan Murthykumar
Background: Cytokine IL18, also known as IFN-inducing factor, is an important regulator of innate and acquired immune responses and plays a number of roles in chronic inflammation and dysfunction autoimmune disorder. Several polymorphisms in the IL18 promoter region have been identified. As there is little evidence for IL18 polymorphisms and periodontitis, this study aimed to evaluate the genetic association of polymorphisms of the IL18 gene (rs1946518). Materials and Methods: A total of 100 subjects were recruited for this study, including 50 patients with periodontitis (stage II, III and grade B) and 50 patients with healthy gingiva clinically intact periodontium. Genomic DNA was extracted from the blood obtained from the subjects. DNA was amplified using primers specific to the MseI region of the IL18 receptor gene. Amplicon was further genotyped using the restriction fragment length using the BtgI enzyme. Genotyping obtained on the basis of the RFLP model was recorded and used for statistical analysis. The distributions of genotypes and allele frequencies in the periodontal disease group and the control group were compared using the Chi Square test. Risks associated with individual alleles or genotypes were calculated using odds ratios (ORs) with 95% confidence intervals. Statistical significance in all trials was determined at p <0.05. Result: The frequencies of genotypes and the distribution of IL18 receptor MseI polymorphisms were not significantly different at ꭕ2df (P = .818). The results of our study showed that there was no significant difference between homozygous and heterozygous genotypes (GG vs TG TT) between periodontitis patients and control group with a P value of 0.8316. The detection frequencies of the TG (20% vs 22%) and TT (14% vs 10%) genotypes showed a significant difference (P value = 0.8316) between the control and experimental groups. experience. There were no significant differences for the G allele (76% vs 79%) and the T allele (24% vs 21%) between the experimental and control groups. Conclusions: The present study indicated that the polymorphism of the IL18 gene was not associated with CP in the analyzed study group.
背景:细胞因子IL18，又称ifn诱导因子，是先天和获得性免疫反应的重要调节因子，在慢性炎症和自身免疫性疾病中发挥多种作用。已经确定了IL18启动子区域的几个多态性。由于IL18基因多态性与牙周炎之间的关联证据较少，本研究旨在评估IL18基因(rs1946518)多态性与牙周炎之间的遗传关联。材料与方法:本研究共招募100名受试者，包括50名牙周炎患者(II期、III期和B级)和50名健康牙龈临床完整牙周组织的患者。从受试者的血液中提取基因组DNA。利用il - 18受体基因MseI区特异性引物扩增DNA。利用BtgI酶进一步利用限制性片段长度对扩增子进行基因分型。记录基于RFLP模型得到的基因分型并进行统计分析。采用卡方检验比较牙周病组与对照组基因型及等位基因频率的分布。使用比值比(ORs)计算与单个等位基因或基因型相关的风险，置信区间为95%。所有试验均以p <0.05为差异有统计学意义。结果:在ꭕ2df上，基因型频率和IL18受体MseI多态性分布无显著性差异(P = .818)。本研究结果显示，牙周炎患者与对照组纯合子与杂合子基因型(GG vs TG TT)差异无统计学意义，P值为0.8316。TG (20% vs 22%)和TT (14% vs 10%)基因型检出率在对照组和试验组之间差异有统计学意义(P值= 0.8316)。体验。G等位基因(76% vs 79%)和T等位基因(24% vs 21%)在实验组和对照组之间无显著差异。结论:本研究表明，在分析的研究组中，il - 18基因多态性与CP无关。
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