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Anti Inflammatory activity of AgNps synthesized using flower formulation (Rosa andJasminum 花制剂(玫瑰和茉莉)合成AgNps的抗炎活性
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.01.25
R. Bharath, A. Arthanari, S. Rajeshkumar
Introduction: In recent years, there has been a resurgence in the use of traditional medicinal herbs, and as a result, pharmaceutical companies are investing heavily in developing natural medications derived from plants. Nanoparticles act in a number of potential ways and fields. Chemical synthesis of nanoparticles is no longer advantageous compared to plant-based synthesis. The current study uses a green method to create silver nanoparticles (AgNPs) utilizing flower extract. Materials and methods: The anti-inflammatory activity for gel was tested by the following convention proposed by Muzushima and Kabayashi with specific alterations. 0.05 mL of Rosa and jasminum jel of various fixations. Result: Using rosa and jasminum extract in the manufacture of silver nanoparticles, the nanoparticles showed remarkable antioxidant and anti-inflammatory activity. It was discovered that the cytotoxic effect was less harmful, demonstrating biocompatibility. Rosa jasminum extract of AgNps showed good anti-inflammatory efficacy in the EA and BSA assays. Conclusion: From our study we concluded that Silver nanoparticles were created using rosa and jasminum extract, and the nanoparticles displayed impressive anti-inflammatory.
引言:近年来,传统草药的使用有所复苏,因此,制药公司正在大力投资开发从植物中提取的天然药物。纳米粒子在许多潜在的方式和领域中起作用。与植物合成相比,化学合成纳米颗粒不再具有优势。目前的研究使用一种绿色方法利用花提取物制造银纳米粒子(AgNPs)。材料和方法:凝胶的抗炎活性测试采用Muzushima和Kabayashi提出的惯例,并进行了特异性改变。不同固定物的玫瑰和茉莉凝胶0.05 mL。结果:利用玫瑰和茉莉提取物制备纳米银,纳米银具有明显的抗氧化和抗炎活性。发现细胞毒性作用危害较小,显示出生物相容性。AgNps玫瑰茉莉提取物在EA和BSA试验中显示出良好的抗炎作用。结论:从我们的研究中,我们得出结论,银纳米粒子是用玫瑰和茉莉提取物制造的,纳米粒子表现出令人印象深刻的抗炎作用。
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引用次数: 0
Comparison between Visual shade selection and Instrumental Shade Determination using Intra Oral Scanner and Digital Spectrophotometer 口腔内扫描仪和数字分光光度计目视色度选择与仪器色度测定的比较
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.02.13
H. Maksoud, Shara Sajini, B. Eid, Sulaiman Alhssaini, Yazeed H. Alanazi
Background: Improper shade selection is one of the most common causes behind restorations’ remake and patient dissatisfaction. Multiple protocols and devices have been proposed to address the limitations of visual shade selection. Objective: To compare the accuracy of dental shade matching gathered visually with both VITA Classical (VC) and VITA 3D-Master (V3D) shade guides with those obtained instrumentally with both 3Shape Trios 3 and VITA Easyshade® Advance 4.0. Materials and Methods: For visual shade selection (VSS), one- hundred participants from King AbdulAziz University, Faculty of Dentistry participated in the study and asked to select the shade of six masked shade tabs from both VC [A1, A2, B1] and V3D [1M1, 2M3, 3R1.]. Later, Instrumental shade determination (ISD) was completed by one experienced participant for six cycles using: VEasy and Trios 3. Results: Significant difference was found between VSS and ISD. The results suggested that although participants significantly preferred VC over V3D in terms of VSS, this did not improve the shade selection performance. Besides, in ISD, no significant difference was reported between VEsay and Trios 3. There was no statistical significance difference between neither Trios 3 when combined with VC and V3D nor between VEasy when combined with VC and V3D. VEasy showed the best shade selection performance when combined with V3D, although the difference was non-significant. Conclusion: The result of the present study supports the promising use of the intra oral scanner 3Shape Trios 3 and dental spectrophotometer VITA Easyshade® Advance 4.0. Combination with a visual selection method may result in more accurate and reliable results.
背景:荫蔽选择不当是导致修复体重做和患者不满意的最常见原因之一。已经提出了多种协议和设备来解决视觉阴影选择的局限性。目的:比较VITA classic (VC)和VITA3D-Master (V3D)色度指南与3Shape Trios 3和VITA Easyshade®Advance4.0仪器获得的牙齿色度匹配的准确性。材料和方法:为了进行视觉阴影选择(VSS),来自阿卜杜勒阿齐兹国王大学牙科学院的100名参与者参与了这项研究,并被要求从VC [A1,A2, B1]和V3D [1M1, 2M3, 3R1]中选择六个遮罩阴影标签的阴影。随后,一名有经验的参与者使用VEasy和Trios 3完成了六个周期的仪器色度测定(ISD)。结果:VSS与ISD有显著性差异。结果表明,尽管参与者在VSS方面明显更喜欢VC而不是V3D,但这并没有提高阴影选择性能。此外,在ISD方面,VEsay与Trios 3无显著差异。Trios 3与VC、V3D合用、VEasy与VC、V3D合用均无统计学差异。VEasy在与V3D组合时表现出最佳的阴影选择性能,尽管差异不显著。结论:本研究结果支持口腔内扫描仪3Shape Trios 3和牙科分光光度计VITA easysshade®Advance 4.0的应用前景。结合视觉选择方法可能会产生更准确和可靠的结果。
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引用次数: 0
Arterial Embolization; A Lifesaving Solution in Placenta Accreta spectrum Post Hysterectomy: A Case Report 动脉栓塞;子宫切除术后增生性胎盘谱的一种救命方法:1例报告
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.01.12
Samera F. AlBasri
Case Summary: A 25-year-old woman who was referred to our hospital at 38 week’s gestation from another hospital as a case of placenta previa with possible accreta. She underwent cesarean hysterectomy and encountered sever postpartum hemorrhage that required massive transfusion of blood products and arterial embolization which was done and saved her life without further morbidity. Conclusion: With increased prevalence of placenta accreta spectrum, arterial embolization facility should be an integral part of treatment protocol to save maternal life.
病例总结:一名25岁的女性在妊娠38周时从其他医院转诊至我院,诊断为前置胎盘伴可能增生。她接受了剖宫产子宫切除术,出现了严重的产后出血,需要大量的血液制品输血和动脉栓塞,这挽救了她的生命,没有进一步的发病率。结论:随着胎盘增生谱的增加,动脉栓塞设备应成为挽救产妇生命的治疗方案中不可或缺的一部分。
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引用次数: 0
Enhancing Upper Extremity Function in Chronic Stroke Patients: Exploration of the Impact of Multimodal Mental Practice Approach 增强慢性脑卒中患者上肢功能:多模式心理练习方法的影响探讨
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.03.33
M. Alqahtani
Objective: The present study aims to explore the impact of a multimodal mental practice approach on enhancing upper extremity function in chronic stroke patients. Specifically, we seek to investigate the potential benefits of incorporating MMP into the existing rehabilitation protocols for stroke survivors and assess its effectiveness in improving motor outcomes. Methods: The study utilized a randomized controlled trial design with chronic stroke patients who experienced upper extremity impairments. The participants were provided multimodal physical practice, multimodal mental practice, and blended multimodal practice regimen for three months. Results: The ANOVA analysis revealed a significant difference among the groups for the MMPG measure, indicating that the Blended Multimodal Practice Group (BMPG) performed significantly better compared to the Multimodal Physical Practice Group (MPPG) and the Multimodal Mental Practice Group (MMPG). Conclusion: The findings of this study suggest that incorporating multimodal mental practice approaches into stroke rehabilitation programs can enhance upper extremity function in chronic stroke patients.
目的:探讨多模式心理练习对慢性脑卒中患者上肢功能的影响。具体而言,我们试图调查将MMP纳入卒中幸存者现有康复方案的潜在益处,并评估其在改善运动预后方面的有效性。方法:本研究采用随机对照试验设计,纳入上肢损伤的慢性脑卒中患者。参与者进行了为期3个月的多模式物理练习、多模式心理练习和混合多模式练习方案。结果:方差分析显示,混合多模态练习组(BMPG)的表现明显优于多模态物理练习组(MPPG)和多模态心理练习组(MMPG)。结论:本研究结果表明,将多模式心理练习方法纳入脑卒中康复方案可以改善慢性脑卒中患者的上肢功能。
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引用次数: 0
Synergistic Activity of Moringa Oleifera and Thyme Vulgaris Essential Oil Against Streptococcus Mutans: An Observational Study 辣木和百里香精油对变形链球菌协同作用的观察研究
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.01.29
Sadhana Karunakaran, P. Sinduja, R. Priyadharshini, P. Ganesh
Background: Dental caries still remain a highly prevalent disease among all age groups especially children. It is caused due to repetitive and/or prolonged demineralization of tooth enamel caused by exposure to low pH from organic acids produced by acidogenic oral bacteria during fermentation of dietary carbohydrates. Streptococcus mutans is a facultative anaerobic , gram positive cocci commonly found in the human oral cavity which plays an important role in causing dental caries. Moringa oleifera Lam. (drumstick tree) is a Moringaceae family member which possesses a variety of advantageous biological properties, such as immunomodulatory, anticancer, antiulcer and antimicrobial properties. Thymus vulgaris is a pleasant smelling perennial shrub which has a direct influence on many bacteria species. The use of combinations of these two EOs and their components are thus a new approach to increase the antimicrobial efficacy of EOs , taking advantage of their synergistic and additive effects. Materials and methods: The broth microdilution method was used to determine the minimum inhibitory concentration(MIC) of the essential oils. The MIC of Moringa, Thyme and combination of the both essential oils against S.mutans which were used in the assay were assessed at a different concentration level. Results: The antimicrobial activity of M.oleifera, T.vulgaris and combination of both the essential oils was proven with the MIC value of 2.5%v/v, 0.03906% and 0.03906% respectively. Conclusion: The combination of Moringa oleifera and Thymus vulgaris essential oil can be used as a good antimicrobial agent to treat various Streptococci borne oral infections. Further incorporation of this oil into the drug formulations is also recommended to treat S.mutans borne oral as well as systemic infections.
背景:龋齿在所有年龄组尤其是儿童中仍然是一种非常普遍的疾病。它是由于在膳食碳水化合物发酵过程中,口腔产酸细菌产生的有机酸产生的低pH值,导致牙釉质反复和/或长时间脱矿而引起的。变形链球菌是一种兼性厌氧革兰氏阳性球菌,常见于人类口腔,在引起龋齿中起重要作用。辣木。辣木(drumstick tree)是辣木科的一种植物,具有免疫调节、抗癌、抗溃疡和抗菌等多种生物学特性。百里香是一种气味宜人的多年生灌木,对许多细菌种类有直接影响。因此,使用这两种EOs及其成分的组合是利用其协同和加性效应来提高EOs抗菌功效的新方法。材料与方法:采用微量肉汤稀释法测定精油的最低抑菌浓度。测定了辣木、百里香和两种精油组合在不同浓度下对变形链球菌的抑制作用。结果:油菜花挥发油、凡夫草挥发油及两种挥发油联合抑菌效果良好,MIC值分别为2.5%v/v、0.03906%和0.03906%。结论:辣木与寻常胸腺精油联合应用可作为一种较好的抗菌药物治疗多种链球菌性口腔感染。还建议将这种油进一步掺入药物制剂中,以治疗变形链球菌传播的口服和全身感染。
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引用次数: 0
Polymeric nanoparticle of Ebastine: Formulation, Characterization and in vitro Evaluation 聚合物纳米颗粒的制备、表征及体外评价
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.01.03
H. Ali, N. Rajab
The main aim of this research work was the development and evaluation of polymeric nanoparticle for the bioavailability improvement of Ebastine (EBT) to treat allergic condition. EBT is a piperidine derivative that binds preferentially to peripheral H1 receptors and is a long-acting, non-sedating second-generation histamine receptor antagonist. It is practically insoluble in water (class II, according to BCS). This work aims to formulate and adjust Ebastine polymeric nanoparticles to improve the EBT solubility as well as dissolution rate. For the synthesis of PNPs, the solvent evaporation technique was used, and three different types of stabilizer that used (HPMC E5, Soluplus, tween 80). The particle size analysis indicated that the optimized formula EBT 9 had a reduced nanoparticulate size of 42 nm, with a 90 percent increase in in-vitro dissolution profile compared to 17 percent for the comparison Ebastine powder in 0.1 N HCl media (pH 1.2). As a result, polymeric nanoparticles formulation of weakly water soluble EBS greatly improved the drug's dissolving rate and increased its solubility.
本研究的主要目的是开发和评价聚合物纳米颗粒,提高依巴斯丁(EBT)治疗过敏性疾病的生物利用度。EBT是一种哌啶衍生物,优先结合外周H1受体,是一种长效,非镇静的第二代组胺受体拮抗剂。它几乎不溶于水(根据BCS分类为II类)。本工作旨在制备和调整EBT聚合物纳米颗粒,以提高EBT的溶解度和溶解速度。采用溶剂蒸发法合成PNPs,采用了三种不同类型的稳定剂(HPMC E5, Soluplus, tween 80)。粒径分析表明,优化后的EBT 9的纳米颗粒尺寸减小至42 nm,体外溶出度增加90%,而对照Ebastine粉在0.1 N HCl (pH 1.2)介质中的体外溶出度增加17%。因此,弱水溶性EBS的聚合物纳米颗粒配方大大提高了药物的溶解速度,增加了其溶解度。
{"title":"Polymeric nanoparticle of Ebastine: Formulation, Characterization and in vitro Evaluation","authors":"H. Ali, N. Rajab","doi":"10.5455/jcmr.2023.14.01.03","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.03","url":null,"abstract":"The main aim of this research work was the development and evaluation of polymeric nanoparticle for the bioavailability improvement of Ebastine (EBT) to treat allergic condition. EBT is a piperidine derivative that binds preferentially to peripheral H1 receptors and is a long-acting, non-sedating second-generation histamine receptor antagonist. It is practically insoluble in water (class II, according to BCS). This work aims to formulate and adjust Ebastine polymeric nanoparticles to improve the EBT solubility as well as dissolution rate. For the synthesis of PNPs, the solvent evaporation technique was used, and three different types of stabilizer that used (HPMC E5, Soluplus, tween 80). The particle size analysis indicated that the optimized formula EBT 9 had a reduced nanoparticulate size of 42 nm, with a 90 percent increase in in-vitro dissolution profile compared to 17 percent for the comparison Ebastine powder in 0.1 N HCl media (pH 1.2). As a result, polymeric nanoparticles formulation of weakly water soluble EBS greatly improved the drug's dissolving rate and increased its solubility.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"16 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82348736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Acupuncture at Bi'nao increases the recovery of hypophasis in patients with incomplete recovered Bell’s palsy: a randomized controlled clinical trial and task-state fMRI study 针刺痹脑可促进不完全康复贝尔氏麻痹患者垂体功能恢复:一项随机对照临床试验和任务状态fMRI研究
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.02.37
Zhidan Liu, Chuang Zhao, Xiaoyan Li, Chunlan Chen, Zunyuan Li, Wenge Huo, Jiang-bo He
Objectives: To evaluate the efficiency of acupuncture at the acupoint of Bi’nao for hypophasis and the mechanisms responsible for effect in the cerebral cortex. Methods: Participants with hypophasis were selected from patients with incompletely recovered Bell’s palsy and randomly allocated into Bi’nao group, Sham Bi’nao group and healthy control group with 33 participants per group. Acupuncture therapy was applied at the real or sham Bi’nao acupoint to compare efficiency. Clinical effects were evaluated by the House-Brackman Scale (HBS), Eye Crack Width Measurement (ECWM) scale and Eyelid Strength Assessment (ESA) before and after therapy. Regions of the brain cortex that were stimulated by acupuncture were detected by task-state functional magnetic resonance imaging. Results: HBS and ESA scores in the Bi’nao group were lower than in the other two groups (P<0.05) while ECWM scores were higher (P<0.05). The cingulate cortex and cerebellum were activated during acupuncture stimulation in the Bi’nao group when compared to both the Sham Bi’nao group and the healthy control group (P<0.05). Conclusion: Acupuncture at the acupoint Bi’nao increased the recovery of hypophasis in patients with incomplete recovered Bell’s palsy. The underlying mechanism might be associated with the activation of the cingulate cortex and cerebellum.
目的:探讨针刺痹脑穴治疗垂体功能障碍的疗效及其在大脑皮层的作用机制。方法:从未完全康复的贝尔麻痹患者中选取垂体功能减退患者,随机分为痹脑组、深部痹脑组和健康对照组,每组33例。采用针刺治疗真、假痹脑穴,比较疗效。治疗前后采用House-Brackman量表(HBS)、眼裂宽度测量量表(ECWM)和眼睑强度评估量表(ESA)评价临床效果。通过任务状态功能磁共振成像检测针刺刺激的大脑皮层区域。结果:痹脑组HBS、ESA评分低于其他两组(P<0.05), ECWM评分高于其他两组(P<0.05)。针刺刺激时,笔脑组扣带皮层和小脑被激活,与假笔脑组和健康对照组比较,差异有统计学意义(P<0.05)。结论:针刺痹脑穴可促进不完全康复贝尔氏麻痹患者垂体功能的恢复。潜在的机制可能与扣带皮层和小脑的激活有关。
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引用次数: 0
Efficiency of life style change in IBS in Alqunfudah governate and its villages 阿尔昆富达省及其村庄IBS患者生活方式改变的效率
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.03.31
N. Qusty, Anas Sarhan, Hassan Alsuhabi, Ali A Alsyed, Abdullah A Alrashdi, Mohammed A. Alessa, Haitham H Alzubaidi, Musleh Alzubaidi, Majed S. Almutairi, Ebrahem R Alsohabi, M. Taha
Background: Irritable bowel syndrome (IBS) is the commonest functional gastrointestinal disorder with worldwide prevalence 11.2%, IBS characterized by recurrent colicky or cramping abdominal pain and altered bowel habit. Methods: A cross sectional study was conducted among AL Qunfudhah population with total 1003 of participants who were asked to complete questionnaires. Results: 28.9% were affected with IBS, this study shows higher predominance in females than males, The most common symptoms among our participants were bloating 37.1%, abdominal pain 26.8% and constipation 20.4%.24.4% were suffering from constipation or diarrhea in the morning and these symptoms affected by spicy food and fried food. Conclusion: Based on our findings, the predominance of IBS among females was higher. Bloating and abdominal pain were the commonest symptoms. Anxiety and depression affect IBS symptoms significantly. Our study emphasizes the correlation between certain foods and IBS symptoms. High fiber diet and low carbohydrate diet will improve the IBS symptoms.
背景:肠易激综合征(IBS)是最常见的功能性胃肠道疾病,全球患病率为11.2%,IBS的特征是复发性绞痛或绞痛性腹痛和排便习惯改变。方法:对AL群富达人群进行横断面研究,共1003人完成问卷调查。结果:28.9%的人患有IBS,女性的患病率高于男性,最常见的症状是腹胀37.1%,腹痛26.8%,便秘20.4%。24.4%的人在早上出现便秘或腹泻,这些症状与辛辣食物和油炸食物有关。结论:根据我们的研究结果,IBS在女性中的患病率更高。腹胀和腹痛是最常见的症状。焦虑和抑郁会显著影响肠易激综合征的症状。我们的研究强调了某些食物与肠易激综合征症状之间的相关性。高纤维饮食和低碳水化合物饮食可以改善肠易激综合征的症状。
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引用次数: 0
Prevention of Cardiovascular Diseases in Young People 预防青年人心血管疾病
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.02.27
Polina Terenteva, M. Fomina, Olesya Zimoglyad, Elizaveta Korotkaya, Elena Mikhailova, Yuriy Pyzhurin
The article examines the features of prevention of cardiovascular diseases in young people. The author notes that cardiovascular diseases are among the most common diseases worldwide and cause a significant number of deaths and disabilities. According to the World Health Organization (WHO), cardiovascular diseases are the leading cause of death in the world, and they account for about 31% of all deaths. Many of the risk factors for the development of cardiovascular diseases in young patients can be prevented by preventive measures, such as proper nutrition, moderate physical activity, quitting smoking and alcohol consumption, weight and blood pressure control, as well as regular medical examinations. In addition, the popularization of a healthy lifestyle, carried out through lectures, presentations, etc., plays an important role.
这篇文章探讨了预防年轻人心血管疾病的特点。提交人指出,心血管疾病是世界上最常见的疾病之一,造成大量死亡和残疾。根据世界卫生组织(WHO)的数据,心血管疾病是世界上导致死亡的主要原因,约占所有死亡人数的31%。年轻病人患心血管疾病的许多危险因素可以通过预防措施加以预防,例如适当的营养、适度的体育活动、戒烟和戒酒、控制体重和血压,以及定期体检。此外,通过讲座、演讲等方式进行的健康生活方式的普及也起着重要作用。
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引用次数: 0
Neurological Consequences of Arvi 阿尔维的神经后果
IF 0.6 Pub Date : 2023-01-01 DOI: 10.5455/jcmr.2023.14.03.06
Khyadi Khabrieva, Soltanat Utegenova, A. Polyakov, Zalina Dogaeva, Timur RustamovichImamutdinov, Alexander Markov
This work includes consideration of neurological consequences of acute respiratory viral infection (ARVI), such as meningitis, encephalitis, headache, sleep disorders and mental disorders. The authors are based on existing studies showing that ARVI can cause inflammatory processes in the nervous system and lead to long-term health consequences. The article also discusses methods of diagnosis and treatment of neurological manifestations of ARVI. The research results may be useful for doctors treating patients with acute respiratory viral infections, as well as for people who want to understand the possible consequences of this disease. In addition, the authors note that the neurological consequences of ARVI can be especially dangerous for certain groups of patients, such as children, the elderly and people with concomitant diseases. Therefore, it is important to pay attention to the neurological symptoms of ARVI and to carry out timely diagnosis and treatment. The paper also notes that possible causes of neurological manifestations of ARVI may be not only viruses, but also immune mechanisms, as well as other factors such as stress and lack of physical activity during the disease. In general, the article provides an overview of the neurological consequences of ARVI, indicating their severity and the need for additional research in this area. This information can be useful both for doctors and for the general public, helping to understand the importance of prevention and timely treatment of acute respiratory viral infections.
这项工作包括考虑急性呼吸道病毒感染(ARVI)的神经系统后果,如脑膜炎、脑炎、头痛、睡眠障碍和精神障碍。作者基于现有的研究表明,ARVI可以引起神经系统的炎症过程,并导致长期的健康后果。本文还讨论了ARVI神经学表现的诊断和治疗方法。研究结果可能对治疗急性呼吸道病毒感染患者的医生以及想要了解这种疾病可能后果的人有用。此外,作者指出,ARVI的神经系统后果对某些患者群体尤其危险,如儿童、老年人和伴有疾病的人。因此,重视ARVI的神经系统症状,及时进行诊断和治疗是非常重要的。这篇论文还指出,ARVI的神经系统表现的可能原因可能不仅仅是病毒,还有免疫机制,以及其他因素,如疾病期间的压力和缺乏身体活动。总的来说,本文概述了ARVI的神经学后果,指出了其严重性和该领域进一步研究的必要性。这些信息对医生和公众都很有用,有助于了解预防和及时治疗急性呼吸道病毒感染的重要性。
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引用次数: 0
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Journal of Complementary Medicine Research
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