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2010 International Conference on Optical MEMS and Nanophotonics最新文献

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X-ray imaging test for a single-stage MEMS X-ray optical system 单级MEMS x射线光学系统的x射线成像测试
Pub Date : 2010-12-17 DOI: 10.1109/OMEMS.2010.5672138
I. Mitsuishi, Y. Ezoe, K. Ishizu, T. Moriyama, Y. Maeda, T. Hayashi, T. Sato, M. Mita, N. Yamasaki, K. Mitsuda, M. Horade, S. Sugiyama, R. Riveros, T. Boggs, H. Yamaguchi, Y. Kanamori, K. Nakajima, R. Maeda
An X-ray imaging test for an X-ray optical system based on MEMS technologies was conducted at the ISAS 30 m beamline. An X-ray reflection and focusing were successfully verified at Al Kα 1.49 keV for the first time. The image quality estimated as a half power diameter was ~20 arcmin. This was consistent with the angular resolution estimated from the surface roughness of 200 nm rms at 100 μm scale. In this paper, the experimental setup and the result of X-ray imaging analysis are reported.
在ISAS 30 m光束线上对基于MEMS技术的x射线光学系统进行了x射线成像测试。首次在Al Kα 1.49 keV下成功验证了x射线反射和聚焦。半功率直径的图像质量估计为~20角分。这与100 μm尺度下200 nm rms的表面粗糙度估计的角分辨率一致。本文报道了实验装置和x射线成像分析结果。
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引用次数: 0
Remote switching of cellular activity using light through quantum dots 利用光通过量子点远程切换细胞活动
Pub Date : 2010-12-17 DOI: 10.1109/OMEMS.2010.5672180
K. Lugo, X. Miao, F. Rieke, Lih Y. Lin
We report integration of CdTe quantum dot (QD) film with LnCap (prostate cancer) cell and CdSe QD probes with cortical neurons for control of cellular activity. We demonstrate the remote switching of cellular activity by exciting QDs with light. Changes in membrane potential and ionic currents are recorded using the patch-clamp method. Upon excitation, the cell shows activation of ion channels and hyperpolarization of the cell membrane.
我们报道了CdTe量子点(QD)薄膜与LnCap(前列腺癌)细胞和CdSe量子点探针与皮质神经元的整合,以控制细胞活性。我们用光激发量子点来证明细胞活动的远程开关。膜片钳法记录了膜电位和离子电流的变化。在兴奋时,细胞表现出离子通道的激活和细胞膜的超极化。
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引用次数: 0
Low cost and large deflection angle polymer MEMS mirror using glass substrate 采用玻璃基板的低成本大偏转角聚合物MEMS反射镜
Pub Date : 2010-12-17 DOI: 10.1109/OMEMS.2010.5672201
O. Sasaki, Takaaki Suzuki, K. Terao, H. Takao, F. Oohira
In this paper, we propose a polymer MEMS mirror device which has the futures of the large deflection angle and the low cost fabrication. Many conventional MEMS mirror devices have been composed of Si wafer and, the expensive dry etching equipment has been necessary when etching the Si substrate. Then, we propose new composition and the novel fabrication method without the dry etching process by using the inexpensive glass substrate. Also, the torsion bar is composed of a photosensitive polymer that is a low rigid material and can be easily fabricated by the photolithography process. A multilayer wiring process is examined so that the low current actuation and the large deflection angle is attained. The fabricated device showed the large optical deflection angle of more than ±40 degrees at the current of ±16mA when the torsion bar length was 1800µm. The variation of the optical deflection angle was within 0.8 degrees at the 106 times repeatability test.
在本文中,我们提出了一种具有大偏转角和低制造成本的聚合物MEMS反射器件。许多传统的MEMS镜像器件都是由硅晶片构成的,在对硅衬底进行刻蚀时,必须使用昂贵的干刻蚀设备。然后,我们提出了新的组合和新的制造方法,而不是使用廉价的玻璃基板进行干蚀刻工艺。此外,扭杆由光敏聚合物组成,该聚合物是一种低刚性材料,可以很容易地通过光刻工艺制造。为了实现小电流驱动和大偏转角,研究了多层布线工艺。当扭杆长度为1800µm时,在±16mA电流下,器件的光学偏转角大于±40°。在106次重复性试验中,光偏转角的变化在0.8度以内。
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引用次数: 1
A fully integrated thermo-pneumatic tunable microlens 一个完全集成的热气动可调微透镜
Pub Date : 2010-12-17 DOI: 10.1109/OMEMS.2010.5672170
Wei Zhang, K. Aljasem, H. Zappe, A. Seifert
A thermo-pneumatically actuated tunable microlens has been developed as a completely integrated system with on-chip actuation and temperature sensing. The focal length of the microlens can be adjusted over a wide range without any external pressure controller. The module consists of a structured silicon chip, a spin-coated PDMS membrane, an optical fluidic chamber, a thermal cavity, and a heating and temperature sensing structure. The focal length is controlled by the applied voltage to the heater and could be tuned in the range between 3.3 and 18.2 mm, corresponding to a temperature variation of 37°C to 24°C, and a change in the numerical aperture from 0.303 to 0.055. At the same time, the cutoff frequency of the optical transfer function, referring to a contrast of 0.2, varies from 30 lines/mm at 27°C to 65 lines/mm at 34°C.
开发了一种热气动驱动的可调微透镜,它是一种集片上驱动和温度传感于一体的集成系统。微透镜的焦距可以在没有任何外部压力控制器的情况下在很宽的范围内调节。该模块由结构化硅芯片、自旋涂覆PDMS膜、光流腔、热腔以及加热和温度传感结构组成。焦距由施加在加热器上的电压控制,可以在3.3到18.2 mm之间进行调节,对应于37°C到24°C的温度变化,以及0.303到0.055的数值孔径变化。同时,光学传递函数的截止频率(参照对比度为0.2)在27℃时为30 lines/mm,在34℃时为65 lines/mm。
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引用次数: 0
Measurements of light fields emerging from fine amplitude gratings 细幅光栅产生的光场测量
Pub Date : 2010-12-17 DOI: 10.1109/OMEMS.2010.5672135
Myun-Sik Kim, T. Scharf, H. Herzig
High resolution amplitude and phase of light fields emerging from a 2-μm-period amplitude grating are measured for different wavelengths. The amplitude gratings lead to highly periodic patterns caused by the Talbot effect. Such patterns reach periodicities of a fraction of the grating period. We discuss the effect of wavelengths and the number of diffraction orders participating in the imaging.
测量了周期为2 μm的振幅光栅在不同波长下产生的高分辨率光场振幅和相位。振幅光栅导致由塔尔博特效应引起的高周期性图案。这种图样达到光栅周期的一小部分的周期性。讨论了波长和参与成像的衍射阶数的影响。
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引用次数: 1
A large rotational angle micromirror based on hypocycloidal electrothermal actuators for endoscopic imaging 基于次摆线电热致动器的大旋转角度微镜内窥镜成像
Pub Date : 2010-12-17 DOI: 10.1109/OMEMS.2010.5672202
X. Mu, Yingshun Xu, Janak Singh, Nanguang Chen, H. Feng, Guangya Zhou, A. Yu, C. Tan, K. Chen, F. Chau
The paper presents a large rotational angle micromirror base on hypocycloidal electrothermal actuators for circumferential endoscopic imaging. The micromirror consists of a double-side Cr/Au coated high reflective mirror plate (1mm by 0.8mm) laterally supported by two hypocycloidal electrothermal actuators on both sides (Fig. 1(a)). In our design, 1µm PVD Al deposited on 2µm single crystal silicon (SCS) forms a bimorph microstructure with the length of 800 µm and the width of 60µm. Four bimorph structures were staggerly connected in parallel to form a hypocycloidal electrothermal actuator. In this configuration, a metal layer was on a silicon backbone in one bimorph structure while the metal layer was deposited below the silicon backbone in adjacent bimorph structures (Fig. 1(b)). Since the radius of curvature of each bimorph structure is the same, the deflection of each structure is the same. Hence the rotational axis keeps still and there is no lateral shifting effect. Simulations via finite element analysis (FEA) show that the mechanical deflection angle of a micromirror significantly increases by using this actuator design. 141.2° was found in the design with fully double-side Al coated actuators (Fig. 2(a, b)) and 68.6° was found in the design with only frontside Al coated actuators (Fig. 2(c, d)). Micromirrors were fabricated by a post-CMOS MEMS process on 8 inches SOI wafers. An optical microscopic image and a scanning electron microscope (SEM) micrograph of a released micromirror are shown in Fig. 3(a) and (b), respectively. However, so far we have not successfully patterned Al layer below the SCS layer as part of the actuator and therefore only micromirrors equipped by frontside Al coated actuators were experimentally characterized (Fig. 4). ∼35° mechanical deflection was achieved by 2.6 V DC input voltage (Fig. 5). It has a discrepancy in comparison in comparison with the FEA simulation. −3dB cutoff frequency was found to be about 29 Hz as the large signal frequency response (Fig. 5). Current-voltage relationship of an electrothermal actuator is also shown in Fig. 5. A series of frames from a video of a switching micromirror shows various tilting angles of the micromirror under a sinusoidal drive signal with the amplitude of 2.6 V was still with absence of microstructures with backside Al coated, the concept of achieving large deflection angle by using hypocycloidal electrothermal actuators has been demonstrated. Both FEA simulation and experimental results prove the capability of the Single-axis rotational micromirror device.
提出了一种基于次摆线电热作动器的大旋转角微镜,用于环向内窥镜成像。微镜由两面镀Cr/Au的高反射镜板(1mm × 0.8mm)组成,两侧由两个次摆线电热致动器支撑(图1(a))。在我们的设计中,1µm PVD Al沉积在2µm单晶硅(SCS)上,形成长800µm、宽60µm的双晶微观结构。四个双晶片结构错开并联连接,形成一个次摆线电热致动器。在这种构型中,金属层位于一个双晶片结构的硅骨架上,而金属层则沉积在相邻双晶片结构的硅骨架下方(图1(b))。由于每个双变形结构的曲率半径是相同的,所以每个结构的挠度是相同的。因此,旋转轴保持静止,没有横向移动的影响。有限元仿真结果表明,采用该致动器设计后,微镜的机械偏转角明显增大。完全双面镀铝致动器的设计为141.2°(图2(a, b)),而仅正面镀铝致动器的设计为68.6°(图2(c, d))。采用后cmos MEMS工艺在8英寸SOI晶圆上制备微镜。释放微镜的光学显微图像和扫描电子显微镜(SEM)显微图像分别如图3(a)和(b)所示。然而,到目前为止,我们还没有成功地将SCS层下方的Al层作为致动器的一部分进行图图化,因此只有由前部Al涂层致动器配备的微镜进行了实验表征(图4)。在2.6 V直流输入电压下实现了~ 35°的机械偏转(图5)。与有限元模拟相比,它存在差异。−3dB截止频率约为29hz,是最大的信号频响(图5)。电热执行器的电流-电压关系如图5所示。从一组切换微镜的视频画面中可以看出,在振幅为2.6 V的正弦驱动信号下,微镜在没有背面镀铝微结构的情况下,仍然具有不同的倾斜角度,证明了利用次摆线电热致动器实现大偏转角的概念。有限元仿真和实验结果均证明了单轴旋转微镜装置的性能。
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引用次数: 3
Development of an integrated microsystem for the multiplexed detection of protein markers in serum using electrochemical immunosensors 电化学免疫传感器用于血清蛋白标记物多路检测的集成微系统的开发
Pub Date : 2010-12-17 DOI: 10.1109/OMEMS.2010.5672208
C. O’Sullivan
Recent advances in the fabrication of microfluidic platforms initiated during the late 90s have facilitated the realisation of micro total analysis systems [1]. The integration of miniaturised fluidic handling and delivery systems with chemical and biochemical sensors provide applied scientists with powerful tools for in-field measurements away from central laboratories [2]. Amongst the various classes of elements able to transduce a chemical or biochemical events into a measurable signal, electrochemical platforms undoubtedly present the most promising advantages. Electrodes of all type, sizes and geometries can easily be integrated within a microfluidic platform and provide excellent sensitivity and versatility in comparison to other transduction techniques based on for example optical or mass sensing [3]. Furthermore, the associated electronics used to drive the electrochemical detection and signal processing can also be easily miniaturised and integrated onto the same platform by carefully designing application specific integrated circuits [4]. We have recently reported a simple and rapid approach for prototype microfluidics and sensor assembly to perform complex protein and genetic electrochemical assays with excellent reproducibility [5]. The microfluidic platform was realized by high precision milling of polycarbonate sheets, which offers flexibility and rapid turn over of the desired designs. Sixteen-electrode sensor arrays were fabricated using photolithographic deposition technologies in order to realize three-electrodes cells comprising of gold counter and working electrodes as well as silver reference electrode. Fluidic chips and electrode arrays were assembled via a laser machined double-sided adhesive gaskets, creating the microchannels necessary for sample and reagent delivery. Surface chemistry methodologies were evaluated in order to achieve the double function of eliminating non-specific binding and optimal spacing of the anchor biocomponents for maximum accessibility to the target proteins. Storage conditions were optimized, demonstrating a long-term stability of the reporter conjugates jointly stored within a single reservoir in the microsystem. The final system has been optimized in terms of incubation times, temperatures and simultaneous, multiplexed detection of the protein markers was achieved in less than 10 minutes with less than ng/mL detection limits. The microsystem has been validated using real patient serum samples and excellent correlation with ELISA results obtained.
上世纪90年代末开始的微流控平台制造的最新进展促进了微总量分析系统的实现[1]。微型流体处理和输送系统与化学和生化传感器的集成为应用科学家提供了远离中心实验室的强大工具[2]。在能够将化学或生化事件转化为可测量信号的各种元素中,电化学平台无疑呈现出最有前途的优势。所有类型、尺寸和几何形状的电极都可以很容易地集成在微流控平台中,与基于光学或质量传感等其他转导技术相比,它们具有出色的灵敏度和通用性[3]。此外,通过精心设计特定应用的集成电路,用于驱动电化学检测和信号处理的相关电子设备也可以很容易地小型化并集成到同一平台上[4]。我们最近报道了一种简单快速的方法,用于原型微流体和传感器组件进行复杂的蛋白质和遗传电化学分析,具有出色的重复性[5]。该微流控平台是通过对聚碳酸酯板材进行高精度铣削而实现的,它提供了所需设计的灵活性和快速翻转。采用光刻沉积技术制备了16电极传感器阵列,实现了由金计数电极、工作电极和银参比电极组成的三电极电池。流体芯片和电极阵列通过激光加工的双面胶粘垫片组装,形成样品和试剂输送所需的微通道。对表面化学方法进行了评估,以实现消除非特异性结合和锚定生物组分的最佳间距的双重功能,以最大限度地接近目标蛋白。优化了储存条件,证明了在微系统中联合储存在单个储存库中的报告基因偶联物具有长期稳定性。最终系统在孵育时间、温度方面进行了优化,同时,在不到10分钟的时间内实现了蛋白质标记物的多重检测,检测限小于ng/mL。该微系统已使用真实患者血清样本进行验证,并与ELISA结果具有良好的相关性。
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引用次数: 1
MEMS scanning mirror used as an laser external modulator for photoacoustic spectroscopy MEMS扫描镜作为光声光谱的激光外调制器
Pub Date : 2010-12-17 DOI: 10.1109/OMEMS.2010.5672157
Li Li, G. Thursby, G. Stewart, D. Uttamchandani
We present a novel MEMS application aimed at laser based gas sensing. A low-cost MEMS based external intensity modulator for a laser diode source has been realised and applied to photoacoustic spectroscopy. By using a MEMS based modulator, pure intensity modulation of the laser emission is achieved without the accompanying wavelength modulation which occurs with diode current modulation. This reduces measurement error. We describe the use of the optical MEMS modulator/photoacoustic technique to recover the profile of the 1535.4nm absorption line of acetylene at 100pm concentration in the photoacoustic cell. Based on initial results, we predict a sensitivity of ∼1ppm with this system.
我们提出了一种新的MEMS应用于激光气体传感。实现了一种低成本的基于MEMS的激光二极管源外强度调制器,并将其应用于光声光谱。通过使用基于MEMS的调制器,实现了激光发射的纯强度调制,而没有伴随二极管电流调制的波长调制。这减少了测量误差。我们描述了利用光学MEMS调制器/光声技术在光声电池中恢复100pm浓度下乙炔1535.4nm吸收线的轮廓。根据初步结果,我们预测该系统的灵敏度为~ 1ppm。
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引用次数: 0
Optical scanning with MEMS in-plane vibratory gratings and its applications 基于MEMS平面振动光栅的光学扫描及其应用
Pub Date : 2010-12-17 DOI: 10.1109/OMEMS.2010.5672205
Guangya Zhou, Y. Du, K. Cheo, Hongbin Yu, F. Chau
MEMS optical scanners are highly desired due to their low-power, high-speed scanning. The in-plane vibratory grating scanner is a development in this area which possesses several unique features. The in-plane scanning minimizes the dynamic deformation, allowing for higher-resolution displays. The dispersive element permits splitting the incoming beam into its constituents for analysis and imaging. Coupling a grating platform to an in-plane moving structure is useful for real-time motion measurement which would otherwise be difficult to analyze. These applications are described including a recent development in the structural design of a double-layer layout which further improves the performance of the grating scanner.
MEMS光学扫描仪因其低功耗,高速扫描而备受青睐。平面内振动光栅扫描器是这一领域的发展,它具有几个独特的特点。平面内扫描最大限度地减少了动态变形,允许更高分辨率的显示。色散元件允许将入射光束分裂成其成分以进行分析和成像。将光栅平台与平面内运动结构耦合,有助于实时运动测量,否则将难以分析。介绍了这些应用,包括最近在双层布局结构设计方面的发展,进一步提高了光栅扫描仪的性能。
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引用次数: 1
Nanostructured origami™ folding of patternable resist for 3D lithography 纳米结构折纸™折叠图案抗蚀剂的3D光刻
Pub Date : 2010-12-17 DOI: 10.1109/OMEMS.2010.5672197
S. Yang, H. Choi, M. Deterre, G. Barbastathis
A new method to fold free standing poly(methyl methacrylate) (PMMA) resist using e-beam exposure is developed and demonstrated. The results prove controllable folding of the patterned PMMA. An explanation of the folding mechanism is proposed based on experimental characterization and theoretical analysis. 3D lithography is achieved by attaching the patterned resist on an adjacent side wall by folding. Patterns are effectively transferred by depositing metal followed by a lift-off process.
提出并论证了一种利用电子束曝光对游离聚甲基丙烯酸甲酯(PMMA)抗蚀剂进行折叠的新方法。实验结果证明了聚甲基丙烯酸甲酯的可折叠性。在实验表征和理论分析的基础上,提出了折叠机理的解释。3D光刻是通过折叠将有图案的抗蚀剂附着在相邻的侧壁上实现的。通过沉积金属,然后进行剥离过程,可以有效地转移图案。
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引用次数: 2
期刊
2010 International Conference on Optical MEMS and Nanophotonics
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