Pub Date : 2021-12-31DOI: 10.47059/revistageintec.v11i4.2658
Tássia Faria de Assis, V. Abreu, P. J. P. Carneiro, M. D’agosto
Urban logistics decision makers face serious challenges in trying to make urban freight transport (UFT) efficient and sustainable. Therefore, it is necessary to identify best practices (BPs) to promote improvements on activity levels, modal shifts to lower-carbon transport systems, lowering energy and intensity, and reducing fuel carbon intensity. This paper conducts an exhaustive literature review that seeks to identify that are directly applicable to BPs promoting sustainable UFT and that indicate the opportunities and challenges of urban logistics. The results indicate that, although BPs make sense for themselves, the most powerful effect occurs when two or more of them are used together, multiplying their strengths. Furthermore, there is an expressive participation of environmental and economic indicators (costs and service levels) to the detriment of social indicators, thus indicating a literary gap.
{"title":"Contribution of Best Practices to Promote Sustainable Urban Freight Transport","authors":"Tássia Faria de Assis, V. Abreu, P. J. P. Carneiro, M. D’agosto","doi":"10.47059/revistageintec.v11i4.2658","DOIUrl":"https://doi.org/10.47059/revistageintec.v11i4.2658","url":null,"abstract":"Urban logistics decision makers face serious challenges in trying to make urban freight transport (UFT) efficient and sustainable. Therefore, it is necessary to identify best practices (BPs) to promote improvements on activity levels, modal shifts to lower-carbon transport systems, lowering energy and intensity, and reducing fuel carbon intensity. This paper conducts an exhaustive literature review that seeks to identify that are directly applicable to BPs promoting sustainable UFT and that indicate the opportunities and challenges of urban logistics. The results indicate that, although BPs make sense for themselves, the most powerful effect occurs when two or more of them are used together, multiplying their strengths. Furthermore, there is an expressive participation of environmental and economic indicators (costs and service levels) to the detriment of social indicators, thus indicating a literary gap.","PeriodicalId":428303,"journal":{"name":"Revista Gestão Inovação e Tecnologias","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130104211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-11DOI: 10.47059/revistageintec.v11i4.2646
Dr. Swapna Gopinath
COVID-19 demands a paradigm shift in modes of human interaction and challenges hegemonic social structures to adapt and evolve themselves to the altered reality of human existence. Across the world, these shifts have been triggered by the new social order threatening to erase existing social systems. My paper attempts to look at the lives of the precariats, caught up within neoliberal structures, assuming these structures to be hegemonic normative systems, and the manner in which they refuse to change, thereby putting the precariats into a more exploitative crisis situation, dehumanizing them, demonizing them, thereby risking their erasure from the socio-political and legal systems that rule the world. I have used the context of India to substantiate my argument. My paper is divided into the following sections: a reading into the concept of precarity and contextualizing it in the neoliberal framework, analysing the pandemic against precarity using examples from Indian society.
{"title":"From Patterns to Freefall: Exposing the Vulnerability of Human Predicament in the Times of the Pandemic","authors":"Dr. Swapna Gopinath","doi":"10.47059/revistageintec.v11i4.2646","DOIUrl":"https://doi.org/10.47059/revistageintec.v11i4.2646","url":null,"abstract":"COVID-19 demands a paradigm shift in modes of human interaction and challenges hegemonic social structures to adapt and evolve themselves to the altered reality of human existence. Across the world, these shifts have been triggered by the new social order threatening to erase existing social systems. My paper attempts to look at the lives of the precariats, caught up within neoliberal structures, assuming these structures to be hegemonic normative systems, and the manner in which they refuse to change, thereby putting the precariats into a more exploitative crisis situation, dehumanizing them, demonizing them, thereby risking their erasure from the socio-political and legal systems that rule the world. I have used the context of India to substantiate my argument. My paper is divided into the following sections: a reading into the concept of precarity and contextualizing it in the neoliberal framework, analysing the pandemic against precarity using examples from Indian society.","PeriodicalId":428303,"journal":{"name":"Revista Gestão Inovação e Tecnologias","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121444724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-11DOI: 10.47059/revistageintec.v11i4.2647
F. E. D. Da Silva
In appropriate activation of c-MYC proto-oncogene contributes to the development of human cancers. Searches for therapies that target genes and proteins related to neoplastic phenotypes have become frequent. Therefore, inhibiting c-MYC expression has been the target for developing and testing multiple drugs and strategies for the treatment of various human cancers. This study aimed to map scientific and technological productions on the MYC gene at the Scielo, PubMed and Orbit Intelligence platforms between 2000 and 2019. The scientific prospecting revealed 1,259 articles. The most detected categories were: molecular biology, MYC mutations and those addressing the MYC as a drug target or therapeutic strategies. A progressive increase in the number of articles in this last category was found. Technological mapping detected 10,059 patent documents, with 20.2% granted. China and the USA were the largest filers, accounting for more than 40%. Biotechnology was the field with the highest number of patents. Biotechnology and the pharmaceutical sector predominated in the second half of the period investigated, both in scientific and technological prospecting. Our study points to a scientific and technological effort in the development of therapeutic strategies against cancer, in which MYC is among the main targets.
{"title":"Mapping Scientific and Technological Production Related to the MYC Gene","authors":"F. E. D. Da Silva","doi":"10.47059/revistageintec.v11i4.2647","DOIUrl":"https://doi.org/10.47059/revistageintec.v11i4.2647","url":null,"abstract":"In appropriate activation of c-MYC proto-oncogene contributes to the development of human cancers. Searches for therapies that target genes and proteins related to neoplastic phenotypes have become frequent. Therefore, inhibiting c-MYC expression has been the target for developing and testing multiple drugs and strategies for the treatment of various human cancers. This study aimed to map scientific and technological productions on the MYC gene at the Scielo, PubMed and Orbit Intelligence platforms between 2000 and 2019. The scientific prospecting revealed 1,259 articles. The most detected categories were: molecular biology, MYC mutations and those addressing the MYC as a drug target or therapeutic strategies. A progressive increase in the number of articles in this last category was found. Technological mapping detected 10,059 patent documents, with 20.2% granted. China and the USA were the largest filers, accounting for more than 40%. Biotechnology was the field with the highest number of patents. Biotechnology and the pharmaceutical sector predominated in the second half of the period investigated, both in scientific and technological prospecting. Our study points to a scientific and technological effort in the development of therapeutic strategies against cancer, in which MYC is among the main targets.","PeriodicalId":428303,"journal":{"name":"Revista Gestão Inovação e Tecnologias","volume":"183 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116240390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-23DOI: 10.47059/revistageintec.v11i4.2635
Zainab Mohanad Issa Ansaf, Dr.Shaheda Akthar
Verbal autopsy is one of the finest medical process to identify automatically the cause of a death afore medical ascendant entities will certify it. Identifying the exact cause is intricate and fuzzy in nature. The dataset with an exact cause of death is a paramount implement for every country to make the presage about the life style and medical facilities available to the people. Multinomial logistic regression was utilized in our study to relegate the exact cause of death. We used standard datasets like PHMRC and Matlab which were potentially accepted in medical field. The reason to utilize the Multinomial logistic Regression is that most of the dataset is consisting of 0 and 1 values which betoken the presence and absence of value in the attribute. We used three standard metrics like the sensitivity, Chance Corrected Concordance (CCC) and Cause-specific mortality fraction (CSMF) for a comparison of our model with precedent models like Insilico VA, Tariff and InterVA-4. Computed results show that proposed model is better than the precedent models.
{"title":"Automatic Verbal Autopsy Classification Using Multinomial Logistic Regression Classifier by Using Recursive Feature Elimination","authors":"Zainab Mohanad Issa Ansaf, Dr.Shaheda Akthar","doi":"10.47059/revistageintec.v11i4.2635","DOIUrl":"https://doi.org/10.47059/revistageintec.v11i4.2635","url":null,"abstract":"Verbal autopsy is one of the finest medical process to identify automatically the cause of a death afore medical ascendant entities will certify it. Identifying the exact cause is intricate and fuzzy in nature. The dataset with an exact cause of death is a paramount implement for every country to make the presage about the life style and medical facilities available to the people. Multinomial logistic regression was utilized in our study to relegate the exact cause of death. We used standard datasets like PHMRC and Matlab which were potentially accepted in medical field. The reason to utilize the Multinomial logistic Regression is that most of the dataset is consisting of 0 and 1 values which betoken the presence and absence of value in the attribute. We used three standard metrics like the sensitivity, Chance Corrected Concordance (CCC) and Cause-specific mortality fraction (CSMF) for a comparison of our model with precedent models like Insilico VA, Tariff and InterVA-4. Computed results show that proposed model is better than the precedent models.","PeriodicalId":428303,"journal":{"name":"Revista Gestão Inovação e Tecnologias","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130041523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-18DOI: 10.47059/revistageintec.v11i4.2634
Sadokat Asadullaevna Akbarova
Personal development in the education system is ensured by the formation of universal educational actions as the basis of the educational and upbringing process. The concept of universal learning activities takes into account the experience of the competence-based approach, i.e. using the acquired knowledge and skills in practice.
{"title":"Content and Requirements for the Development of Environmental Competence in Future Teachers","authors":"Sadokat Asadullaevna Akbarova","doi":"10.47059/revistageintec.v11i4.2634","DOIUrl":"https://doi.org/10.47059/revistageintec.v11i4.2634","url":null,"abstract":"Personal development in the education system is ensured by the formation of universal educational actions as the basis of the educational and upbringing process. The concept of universal learning activities takes into account the experience of the competence-based approach, i.e. using the acquired knowledge and skills in practice.","PeriodicalId":428303,"journal":{"name":"Revista Gestão Inovação e Tecnologias","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116993844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-12DOI: 10.47059/revistageintec.v11i4.2631
Warqaa Ahmed Irzooqi Al- Shaikhli, Dr. Tahani Mahdi AL-Yasiri, Dr. Hanan Abdullah Hassan
The sea is of paramount importance in the life of man and peoples. Since ancient times, it has represented a tool for communication between nations, a link for civilizational meeting between them, and a source of sustenance. Man’s need and interest in exploiting this wealth moves his curiosity and ambitions to think and search for means that contribute and help in expanding the scope of maritime exploitation and consolidating relations between countries more and more. The maritime field was among the important areas touched by industrial and technological development, especially in the field of maritime transport, which led to the emergence of giant ships capable of embarking on sea voyages and thus moving foreign trade in a positive way. The aim of the research is to know the extent to which ship hull insurance is related to the liquidity and profitability of the National Insurance Company, and where the main research problem is manifested in the extent to which ship hull insurance is linked to the liquidity and profitability of the National Insurance Company. Only the research relied on the questionnaire as a tool for all data and information from the sample of 64 and those who have responsibility are (General Director, Department Director, Division Officer, Unit Officer) and the statistical program was used spss 21 in the calculation standard deviation, simple linear regression, testF ) R² (. The conclusions reached by the research are the evaluation of the degree of risk surrounding the ship and the evaluation of the degree of classification in the classification record is based on which the insurance price for the structures of marine vessels is determined, which shows that the degree of risk varies up and down according to the type of ship, origin, shipping lines, and the experience of the crew and the master. The results of the study also showed the existence of a strong correlation between the liquidity variable and profitability in the respondents' response to the research sample in the National Insurance Company, as there is no profitability without the presence of liquidity and good liquidity expresses the company's ability to meet the payment of its obligations. (*) An extracted thesis, which is part of the requirements for obtaining a higher diploma equivalent to a master’s degree. There are also a number of recommendations, including; Adoption of a unified plan for all insurance branches. To measure the liquidity risk in order to ensure that the company is protected from bankruptcy or its exit from the insurance market in the event of a financial crisis again.
{"title":"An Analytical Study of Ship Hull Insurance in the Liquidity and Profitability of the National Insurance Company","authors":"Warqaa Ahmed Irzooqi Al- Shaikhli, Dr. Tahani Mahdi AL-Yasiri, Dr. Hanan Abdullah Hassan","doi":"10.47059/revistageintec.v11i4.2631","DOIUrl":"https://doi.org/10.47059/revistageintec.v11i4.2631","url":null,"abstract":"The sea is of paramount importance in the life of man and peoples. Since ancient times, it has represented a tool for communication between nations, a link for civilizational meeting between them, and a source of sustenance. Man’s need and interest in exploiting this wealth moves his curiosity and ambitions to think and search for means that contribute and help in expanding the scope of maritime exploitation and consolidating relations between countries more and more. The maritime field was among the important areas touched by industrial and technological development, especially in the field of maritime transport, which led to the emergence of giant ships capable of embarking on sea voyages and thus moving foreign trade in a positive way. The aim of the research is to know the extent to which ship hull insurance is related to the liquidity and profitability of the National Insurance Company, and where the main research problem is manifested in the extent to which ship hull insurance is linked to the liquidity and profitability of the National Insurance Company. Only the research relied on the questionnaire as a tool for all data and information from the sample of 64 and those who have responsibility are (General Director, Department Director, Division Officer, Unit Officer) and the statistical program was used spss 21 in the calculation standard deviation, simple linear regression, testF ) R² (. The conclusions reached by the research are the evaluation of the degree of risk surrounding the ship and the evaluation of the degree of classification in the classification record is based on which the insurance price for the structures of marine vessels is determined, which shows that the degree of risk varies up and down according to the type of ship, origin, shipping lines, and the experience of the crew and the master. The results of the study also showed the existence of a strong correlation between the liquidity variable and profitability in the respondents' response to the research sample in the National Insurance Company, as there is no profitability without the presence of liquidity and good liquidity expresses the company's ability to meet the payment of its obligations. (*) An extracted thesis, which is part of the requirements for obtaining a higher diploma equivalent to a master’s degree. There are also a number of recommendations, including; Adoption of a unified plan for all insurance branches. To measure the liquidity risk in order to ensure that the company is protected from bankruptcy or its exit from the insurance market in the event of a financial crisis again.","PeriodicalId":428303,"journal":{"name":"Revista Gestão Inovação e Tecnologias","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122930101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-09DOI: 10.47059/revistageintec.v11i4.2628
Marzieh Seddighi, S. Salajegheh, M. Kamali, Zahra Shokouh
Higher education centers have become important social organizations that play a major role in the comprehensive and sustainable development of countries. The mission of universities as a learning organization has a great impact on micro and macro government decisions in the short and long term because the product of universities affects the knowledge, insight, characteristics and behavior of graduates as managers and current and future decision makers of the country. This research was conducted with the aim of presenting a favorable model for the implementation of cultural policies of the higher education system in line with the cultural policies of the Islamic Republic of Iran. Descriptive research method was used in this study. The statistical population of the study includes higher education staff in the southeastern provinces of the country. A questionnaire was used to collect data and SPSS software version 23 and AMOS version 23 software were used to analyze the data.
{"title":"Presenting a Favorable Model for Implementing the Cultural Policies of the Higher Education System in Line with the Cultural Policies of the Islamic Republic of Iran","authors":"Marzieh Seddighi, S. Salajegheh, M. Kamali, Zahra Shokouh","doi":"10.47059/revistageintec.v11i4.2628","DOIUrl":"https://doi.org/10.47059/revistageintec.v11i4.2628","url":null,"abstract":"Higher education centers have become important social organizations that play a major role in the comprehensive and sustainable development of countries. The mission of universities as a learning organization has a great impact on micro and macro government decisions in the short and long term because the product of universities affects the knowledge, insight, characteristics and behavior of graduates as managers and current and future decision makers of the country. This research was conducted with the aim of presenting a favorable model for the implementation of cultural policies of the higher education system in line with the cultural policies of the Islamic Republic of Iran. Descriptive research method was used in this study. The statistical population of the study includes higher education staff in the southeastern provinces of the country. A questionnaire was used to collect data and SPSS software version 23 and AMOS version 23 software were used to analyze the data.","PeriodicalId":428303,"journal":{"name":"Revista Gestão Inovação e Tecnologias","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128561491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-29DOI: 10.47059/revistageintec.v11i4.2624
Razieh Moghaddam
Introduction: Nowadays, adolescent and youth’s health has become increasingly important. The world health organization (WHO) emphasizes the importance of evaluating the structure, process, and outcome of health services. This study was conducted to design a health services’ management of adolescents and youth model for the Iranian population, to improve young people's health. Method: This study is a comparative, quantitative-qualitative study. Countries were selected by comparing adolescent and youth health indicators based on population and availability of information. By studying the health services’ management of adolescents and youth, essential variables and dimensions in the initial model were identified, and a preliminary questionnaire was developed and approved by experts. One hundred seventy-eight final questionnaires were completed by experts. Exploratory factor analysis was performed to determine the practical factors (SPSS 20), and the model’s fit was examined by confirmatory factor analysis (Amos 24). Results: A total of 6 factors were identified as effective in health services’ management of adolescents and youth, including, health service package, human resources, financial resources, equipment and services’ provision, data & statistics information resources, and health service delivery management of adolescents and youth, With a maximum 0.97 operating load had the highest and equipment and services’ provision (0.53), had the least impact. Conclusion: The proposed model has the most significant impact on the management of health services’ management of adolescents and youth components.
{"title":"A Comparative Study of Health Services’ Management of Adolescents and Youth in Selected Developed Countries and Iran: Developing a Model for Iran","authors":"Razieh Moghaddam","doi":"10.47059/revistageintec.v11i4.2624","DOIUrl":"https://doi.org/10.47059/revistageintec.v11i4.2624","url":null,"abstract":"Introduction: Nowadays, adolescent and youth’s health has become increasingly important. The world health organization (WHO) emphasizes the importance of evaluating the structure, process, and outcome of health services. This study was conducted to design a health services’ management of adolescents and youth model for the Iranian population, to improve young people's health.\u0000Method: This study is a comparative, quantitative-qualitative study. Countries were selected by comparing adolescent and youth health indicators based on population and availability of information. By studying the health services’ management of adolescents and youth, essential variables and dimensions in the initial model were identified, and a preliminary questionnaire was developed and approved by experts. One hundred seventy-eight final questionnaires were completed by experts. Exploratory factor analysis was performed to determine the practical factors (SPSS 20), and the model’s fit was examined by confirmatory factor analysis (Amos 24).\u0000Results: A total of 6 factors were identified as effective in health services’ management of adolescents and youth, including, health service package, human resources, financial resources, equipment and services’ provision, data & statistics information resources, and health service delivery management of adolescents and youth, With a maximum 0.97 operating load had the highest and equipment and services’ provision (0.53), had the least impact.\u0000Conclusion: The proposed model has the most significant impact on the management of health services’ management of adolescents and youth components.","PeriodicalId":428303,"journal":{"name":"Revista Gestão Inovação e Tecnologias","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131401999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-19DOI: 10.47059/revistageintec.v11i4.2614
Rafael L. C. de Jesus
Erectile dysfunction (ED) is considered a public health problem with numerous risk factors, such as hypertension. Besides the existing oral treatment for ED, there are individuals that do not respond to or present numerous side effects to this therapy. Changes in the TRP channels can lead to several clinical complications, such as hypertension. More specifically, the cooling-sensing TRPM8 channel could be a novel target for the development of new drugs. In this line, menthol, a natural product TRPM8 channel agonist may be a molecule for use to treat erectile dysfunction. Then, we conducted a patent review to evaluate the application of menthol focusing on the treatment of erectile dysfunction. The search was conducted on Espacenet® associating A61K31/045 and A61K36/534 codes or using keywords, “erectile dysfunction AND menthol”. We analyzed 1,331 patents, which fourteen patents were found with the use of menthol in the genitourinary system. Although the patents had menthol in their formulations, none went directly to the development of pharmaceutical applications to treat erectile dysfunction. Taking these data into account, the use of menthol in the treatment of erectile dysfunction has been underexplored and is an opportunity for research and technological development based on a high innovation potential.
{"title":"Menthol for the Treatment of Erectile Dysfunction: Generation and Technology Export","authors":"Rafael L. C. de Jesus","doi":"10.47059/revistageintec.v11i4.2614","DOIUrl":"https://doi.org/10.47059/revistageintec.v11i4.2614","url":null,"abstract":"Erectile dysfunction (ED) is considered a public health problem with numerous risk factors, such as hypertension. Besides the existing oral treatment for ED, there are individuals that do not respond to or present numerous side effects to this therapy. Changes in the TRP channels can lead to several clinical complications, such as hypertension. More specifically, the cooling-sensing TRPM8 channel could be a novel target for the development of new drugs. In this line, menthol, a natural product TRPM8 channel agonist may be a molecule for use to treat erectile dysfunction. Then, we conducted a patent review to evaluate the application of menthol focusing on the treatment of erectile dysfunction. The search was conducted on Espacenet® associating A61K31/045 and A61K36/534 codes or using keywords, “erectile dysfunction AND menthol”. We analyzed 1,331 patents, which fourteen patents were found with the use of menthol in the genitourinary system. Although the patents had menthol in their formulations, none went directly to the development of pharmaceutical applications to treat erectile dysfunction. Taking these data into account, the use of menthol in the treatment of erectile dysfunction has been underexplored and is an opportunity for research and technological development based on a high innovation potential.","PeriodicalId":428303,"journal":{"name":"Revista Gestão Inovação e Tecnologias","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127931224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-19DOI: 10.47059/revistageintec.v11i4.2623
Arshad Hashmi
In recent years, occupational stress mining has become a widely exciting issue in the research field. The primary purpose of this study is to analyze filter feature selection methods for the efficient occupational stress classification model. We propose and examine seven different techniques of filter feature selection such as Chi-Square, Information Gain, Information Gain Ratio, Correlation, Principal Component Analysis, and Relief. The resultant selected features are then used with popular classifiers like Naive Bayes (NB), Random Forest (RF), Support Vector Machine (SVM), Artificial Neural Network (ANN), and Gradient Boosted Trees (GBT) for detection of occupational stress in the insurance sector. A survey-based psychological primary occupational stress data set is used to evaluate the relative performance of these methods. This study effectively demonstrated the significance of filter feature selection methods and explained how accurately they could help classify stress levels. This study showed that the Correlation-based feature selection with the SVM classifier obtained the best performance compared to other filter feature selection methods and classification models.
{"title":"A Comparative Study of Classification of Occupational Stress in the Insurance Sector Using Machine Learning and Filter Feature Selection Techniques","authors":"Arshad Hashmi","doi":"10.47059/revistageintec.v11i4.2623","DOIUrl":"https://doi.org/10.47059/revistageintec.v11i4.2623","url":null,"abstract":"In recent years, occupational stress mining has become a widely exciting issue in the research field. The primary purpose of this study is to analyze filter feature selection methods for the efficient occupational stress classification model. We propose and examine seven different techniques of filter feature selection such as Chi-Square, Information Gain, Information Gain Ratio, Correlation, Principal Component Analysis, and Relief. The resultant selected features are then used with popular classifiers like Naive Bayes (NB), Random Forest (RF), Support Vector Machine (SVM), Artificial Neural Network (ANN), and Gradient Boosted Trees (GBT) for detection of occupational stress in the insurance sector. A survey-based psychological primary occupational stress data set is used to evaluate the relative performance of these methods. This study effectively demonstrated the significance of filter feature selection methods and explained how accurately they could help classify stress levels. This study showed that the Correlation-based feature selection with the SVM classifier obtained the best performance compared to other filter feature selection methods and classification models.","PeriodicalId":428303,"journal":{"name":"Revista Gestão Inovação e Tecnologias","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129082740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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