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2021 IEEE International Symposium on Medical Measurements and Applications (MeMeA)最新文献

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An Optimal Procedure for Stride Length Estimation Using Foot-Mounted Magneto-Inertial Measurement Units 一种基于足载磁惯性测量单元的步长估计优化方法
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478604
Rachele Rossanigo, M. Caruso, F. Salis, S. Bertuletti, U. Croce, A. Cereatti
Stride length is often used to quantitatively evaluate human locomotion performance. Stride by stride estimation can be conveniently obtained from the signals recorded using miniaturized inertial sensors attached to the feet and appropriate algorithms for data fusion and integration. To reduce the detrimental drift effect, different algorithmic solutions can be implemented. However, the overall method accuracy is supposed to depend on the optimal selection of the parameters which are required to be set. This study aimed at evaluating the influence of the main parameters involved in well-established methods for stride length estimation. An optimization process was conducted to improve methods’ performance and preferable values for the considered parameters according to different walking speed ranges are suggested. A parametric solution is also proposed to target the methods on specific subjects’ gait characteristics. The stride length estimates were obtained from straight walking trials of five healthy volunteers and were compared with those obtained from a stereo-photogrammetric system. After parameters tuning, percentage errors for stride length were 1.9%, 2.5% and 2.6% for comfortable, slow, and fast walking conditions, respectively.
步长常用于定量评价人体运动表现。利用附着在脚上的小型惯性传感器记录的信号,通过适当的数据融合和集成算法,可以方便地获得步幅估计。为了减少有害的漂移效应,可以实现不同的算法解决方案。然而,总体方法的精度取决于所需要设置的参数的最佳选择。本研究旨在评估步幅估计方法中涉及的主要参数的影响。为了提高方法的性能,对所考虑的参数在不同步行速度范围内的取值进行了优化。针对特定受试者的步态特征,提出了一种参数化求解方法。步幅估算值来自5名健康志愿者的直线行走试验,并与立体摄影测量系统获得的结果进行了比较。在参数调整后,在舒适、缓慢和快速行走条件下,步长误差百分比分别为1.9%、2.5%和2.6%。
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引用次数: 6
Characterization of EMG time-frequency content during Parkinson walking: a pilot study 帕金森行走时肌电图时频内容的表征:一项初步研究
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478707
M. Romanato, A. Strazza, W. Piatkowska, F. Spolaor, S. Fioretti, D. Volpe, Z. Sawacha, F. Nardo
Surface electromyography (sEMG) is commonly adopted to characterize walking in patients affected by Parkinson’s disease (PD). Timing and morphology of sEMG signal are typically investigated, while poor information on frequency content is available. Thus, the present pilot study was designed to test the hypothesis that continuous wavelet transform (CWT) of sEMG signal is a suitable approach to assess muscle activity during PD-walking task, in both time and frequency domains. To this aim, sEMG signals from 4 leg muscles of 5 patients are acquired during walking and processed to assess CWT-scalogram function. Results show that CWT is able to provide time ranges of muscle-activation over the whole PD population, which matches with what reported in previous studies on PD. The novel contribution of this study consists in achieving a characterization of the frequency content of each one of regions detected in time domain. Although the frequency content does not exceed the typical frequency range between 5 Hz and 450 Hz, different mean frequency contents are observed among muscles and among different activations of the same muscle. In particular, a relevant variability of frequency content is observed for thigh muscles, showing differences up to 180 Hz between stance and swing values. In conclusion, present findings support the use of CWT scalogram for a reliable assessment of muscle activity in time-frequency domain, during walking of PD patients. Outcomes highlight a large inter and intra muscle variability of frequency range, opening a new field of investigation for future studies.
表面肌电图(sEMG)通常用于帕金森病(PD)患者的行走特征。通常对表面肌电信号的时序和形态进行了研究,而关于频率内容的信息很少。因此,本初步研究旨在验证表面肌电信号的连续小波变换(CWT)在时域和频域上是一种评估PD-walking任务期间肌肉活动的合适方法。为此,我们采集了5例患者行走过程中4块腿部肌肉的肌电图信号,并对其进行处理以评估cwt -尺度图功能。结果表明,CWT能够提供整个PD人群的肌肉激活时间范围,这与先前关于PD的研究报告相匹配。本研究的新颖贡献在于实现了在时域中检测到的每个区域的频率内容的表征。虽然频率含量不超过5 Hz - 450 Hz的典型频率范围,但在不同肌肉之间以及同一肌肉的不同激活之间观察到不同的平均频率含量。特别是,在大腿肌肉中观察到频率内容的相关可变性,在站立和摆动值之间显示高达180 Hz的差异。总之,目前的研究结果支持使用CWT尺度图在PD患者行走时可靠地评估肌肉活动的时频域。结果强调了频率范围的巨大肌肉间和内部变异性,为未来的研究开辟了一个新的研究领域。
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引用次数: 2
mHealth application for remote health monitoring useful during the COVID 19 pandemic 用于远程健康监测的移动健康应用程序在COVID - 19大流行期间非常有用
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478717
V. Sandulescu, S. Puscoci, Monica Petre, Minodora Dumitrache, Viorel Bota, Alexandru Gîrlea
The paper presents an application of mHealth – a mobile app for remote health monitoring, that facilitates using a Bluetooth enabled health measuring device and synchronizing health data to a health care services provider’s web portal. The mobile app uses a public API that allows its integration in a complex platform for home care providers, allowing health monitoring of large groups of patients, monitoring vital functions, including body temperature, respiratory rate and arterial blood oxygen saturation, relevant in monitoring COVID-19 patients.
本文介绍了一个移动健康应用程序——一个用于远程健康监测的移动应用程序,它便于使用蓝牙健康测量设备并将健康数据同步到医疗保健服务提供商的门户网站。该移动应用程序使用公共API,可以将其集成到家庭护理提供者的复杂平台中,从而可以对大量患者进行健康监测,监测与监测COVID-19患者相关的重要功能,包括体温、呼吸频率和动脉血氧饱和度。
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引用次数: 2
The use of cognitive training with tDCS for the reduction of impulsiveness and improvement of executive functions: a case study 使用tDCS进行认知训练以减少冲动和改善执行功能:一个案例研究
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478704
N. S. Bonfiglio, Roberta Renati, Ludovica Patrone, D. Rollo, M. P. Penna
Impulsiveness and inhibitory control deficits represent one of the major difficulties in Attention Deficit disorders. It has been seen that these difficulties seem to be related to specific areas of the nervous system, such as the Prefrontal Area and the Inferior Frontal Gyrus. Several studies have shown how it is possible to improve inhibitory control and reduce impulsivity through the use of neurostimulation, in particular by single-session or multi-session protocols. Some of these researches have combined neurostimulation with tDCS with cognitive training, such as card or memory games, to improve the performance of some executive functions related to the frontal and prefrontal areas. The present work presents a treatment carried out on a 21-year-old subject with Attentive Disorder. The treatment consisted of the use of tDCS associated with cognitive training for 12 sessions. Cognitive batteries before starting the treatment and at the end of the treatment, as well as the trials on executive functions before each training session and at the end of the session, were administered. The results show an improvement in cognitive battery assessments before and after treatment. As regards the evaluations of executive function trials carried out for each session, however, the improvements are partial and related to some sessions. The results obtained in this work prove how the use of training, associated with neurostimulation, can represent an effective treatment for individuals with Attention Deficit. The possibility of using the protocol here proposed even remotely and without the assistance of an in presence operator, increases its potential and usefulness in care settings.
冲动和抑制控制缺陷是注意缺陷障碍的主要困难之一。已经发现,这些困难似乎与神经系统的特定区域有关,如前额叶区和额下回。几项研究表明,通过使用神经刺激,特别是单次或多次治疗方案,如何可能改善抑制控制并减少冲动。其中一些研究将神经刺激与tDCS与认知训练(如纸牌或记忆游戏)相结合,以改善与额叶和前额叶区域相关的某些执行功能的表现。目前的工作是对一名21岁的注意力障碍患者进行治疗。治疗包括使用tDCS与认知训练相结合的12个疗程。在开始治疗前和治疗结束时进行认知电池测试,以及在每次训练前和训练结束时进行执行功能测试。结果显示治疗前后认知电池评估有改善。然而,关于为每届会议进行的执行功能试验的评价,改进是局部的,并且与某些会议有关。在这项工作中获得的结果证明了如何使用与神经刺激相关的训练,可以代表一个有效的治疗个体的注意力缺陷。这里提出的使用协议的可能性,即使是远程的,没有在场操作员的帮助,也增加了它在护理环境中的潜力和有用性。
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引用次数: 4
[MeMeA 2021 Front cover] [MeMeA 2021封面]
Pub Date : 2021-06-23 DOI: 10.1109/memea52024.2021.9478759
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引用次数: 0
Characterization of Muscle Phantom Used in Calibration of Physiotherapy Ultrasound: Measurement of Acoustic Parameters of Phantom (2020) 用于物理治疗超声校准的肌肉模体表征:模体声学参数的测量(2020)
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478685
Neslisah Gün, B. Karaböce, S. Yurdalan
Physiotherapy ultrasound is one of the most used electrophysical agents in the clinic for its widely therapeutic effects. To guarantee safe and effective treatment, physiotherapy devices must be capable of applying correct ultrasound radiation to the body (or part of the body) under the procedure. The effectiveness of the therapy depends on the ultrasound device's performance and calibration. For performance testing and calibration, tissue-mimicking phantoms are used. This study's objective is to characterize the acoustic parameters of muscle phantom used in the calibration of physiotherapy ultrasound, by following per under the metrology principles. Muscle phantom was prepared. Then, the phantom's sound speed, attenuation coefficient was measured with the pulse-echo method, density, and acoustic impedance calculations were performed. A detailed uncertainty study in measurements was also presented in the paper. The acoustic parameters of muscle phantom were measured as given; the speed of sound 1549.8 ± 3.89 m/s (expanded uncertainty, U=6.7), attenuation coefficient 1.14 ± 0.8 dB/cm MHz (expanded uncertainty, U=0.55). Its acoustic impedance was calculated as 1.632 MRayl; it's density as 1053.5 kg/ m³. Muscle phantom's acoustic properties were found similar to the muscle tissue. It can be used in testing the physiotherapy ultrasound device's performance and calibration as it is cheap, easy to make, and
物理治疗超声是临床上应用最多的电物理试剂之一,具有广泛的治疗效果。为了保证安全有效的治疗,物理治疗设备必须能够在手术过程中对身体(或身体的一部分)施加正确的超声波辐射。治疗的有效性取决于超声设备的性能和校准。为了进行性能测试和校准,使用了组织模拟模型。本研究的目的是描述用于物理治疗超声校准的肌肉模体的声学参数,根据计量原理。制备肌肉模体。然后,用脉冲回波法测量了模体的声速、衰减系数,计算了密度和声阻抗。本文还对测量中的不确定度进行了详细的研究。肌模的声学参数测量如所示;声速1549.8±3.89 m/s(扩展不确定度,U=6.7),衰减系数1.14±0.8 dB/cm MHz(扩展不确定度,U=0.55)。计算其声阻抗为1.632 MRayl;密度为1053.5 kg/ m³。肌肉幻像的声学特性与肌肉组织相似。它可以用于物理治疗超声设备的性能测试和校准,因为它便宜,容易制作,而且
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引用次数: 0
Data-driven Development of Digital Health Applications on the Example of Dementia Screening 以痴呆症筛查为例的数据驱动的数字健康应用开发
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478676
Markus Schinle, Christina Erler, Timon Schneider, Joana Plewnia, Wilhelm Stork
Following the paradigm of precision medicine, the combination of health data and Machine Learning (ML) is promising to improve the quality of healthcare services e.g. by making diagnoses and therapeutic interventions as early and precise as possible. The implementation of this approach requires sufficient amounts of data with a high quality along the data life cycle. This goal seems recently achievable through the implementation of several national digital health strategies and the hope of a growing societal acceptance of digital health applications due to the implications of the COVID-19 pandemic. But, a collection of tools and methods is missing, which supports developers to use data as driving force of the development process. Due to the iterative nature of software application development, it allows the continuous improvement through the integration of collected digital data. We refer to this as a data-driven approach and identify steps to take and tools for its implementation. Associated challenges and opportunities of this translational approach are outlined on the example of a self-developed dementia screening application. Using our methodology, we compared multiple ML algorithms based on the data of an observational study (n=55) and achieved models with sensitivity up to 89% for unhealthy participants within this use case.
遵循精准医疗的范例,健康数据和机器学习(ML)的结合有望提高医疗服务的质量,例如通过尽可能早和准确地进行诊断和治疗干预。这种方法的实现需要在整个数据生命周期中有足够数量的高质量数据。最近,通过实施若干国家数字卫生战略,以及由于COVID-19大流行的影响,数字卫生应用有望得到越来越多的社会接受,这一目标似乎可以实现。但是,缺少一组工具和方法来支持开发人员使用数据作为开发过程的驱动力。由于软件应用程序开发的迭代性质,它允许通过集成收集的数字数据进行持续改进。我们将其称为数据驱动的方法,并确定要采取的步骤和实现该方法的工具。相关的挑战和机遇,这种转化方法概述了一个例子,自行开发的痴呆症筛查应用。使用我们的方法,我们基于一项观察性研究(n=55)的数据比较了多种ML算法,并在该用例中获得了对不健康参与者灵敏度高达89%的模型。
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引用次数: 3
Distinguishing Stroke patients with and without Unilateral Spatial Neglect by means of Clinical Features: a Tree-based Machine Learning Approach 通过临床特征来区分卒中患者单侧空间忽视:基于树的机器学习方法
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478727
L. Donisi, P. Moretta, A. Coccia, F. Amitrano, A. Biancardi, G. D'Addio
Unilateral Spatial Neglect is a cognitive impairment of neuropsychological interest that is a consequence of stroke able to influence negatively the rehabilitation outcome of patients with stroke. The aim of the study is to explore the feasibility of machine learning to classify stroke patients with and without unilateral spatial neglect using clinical features. We performed the study using a machine learning approach by means the following tree-based algorithms: Decision Tree, Random Forest, Rotation Forest, AdaBoost of decision stumps and Gradient Boost tree using six clinical features both numerical and nominal: Montreal Cognitive Assessment, Functional Independence Measure scale, Barthel Index, aetiology, site of brain lesion and presence of hemiparesis at lower limbs. Tree-based Machine learning analysis achieved interesting results in terms of evaluation metrics scores; the best algorithm was Random Forest with an Accuracy, Sensitivity, Specificity, Precision and Area under the Receiver Operating Characteristic curve equal to 0.92, 0.83, 1.00, 1.00, 0.95 respectively. The study demonstrated the proposed combination of clinical features and algorithms represents a valuable approach to automatically classify stroke patients with and without Unilateral Spatial Neglect. The future investigations on enriched datasets will further confirm the potential application of this methodology as prognostic support to be chosen among those already implemented in the clinical field.
单侧空间忽视是一种神经心理学的认知障碍,是中风的后果,能够对中风患者的康复结果产生负面影响。该研究的目的是探索机器学习的可行性,以分类卒中患者单侧空间忽视和不使用临床特征。我们使用机器学习方法通过以下基于树的算法进行研究:决策树、随机森林、旋转森林、AdaBoost决策树桩和梯度Boost树,使用六个数值和名义临床特征:蒙特利尔认知评估、功能独立测量量表、Barthel指数、病因学、脑损伤部位和下肢偏瘫的存在。基于树的机器学习分析在评估指标得分方面取得了有趣的结果;最佳算法为Random Forest,其准确率为0.92,灵敏度为0.83,特异性为1.00,精密度为1.00,接受者工作特征曲线下面积为0.95。该研究表明,临床特征和算法的结合代表了一种有价值的方法来自动分类卒中患者有无单侧空间忽视。未来对丰富数据集的调查将进一步证实该方法作为预后支持的潜在应用,可在临床领域中选择已实施的方法。
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引用次数: 10
Multiple Input, Single Output Frequency Mixing Communication Technique for Low Power Data Transmission 用于低功率数据传输的多输入单输出混频通信技术
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478708
Giuliana Emmolo, Daryl Ma, Danilo Demarchi, P. Georgiou
The paradigm of Internet of Things (IoT) has revolutionised the field of human health monitoring. Recent research works outline an ever growing interest in the development of miniaturized fully functioning devices, where optimization strategies in terms of size, power consumption and data transmission capabilities represents the main requirements as well as the biggest challenges at the design stage. In this paper we provide an analysis into a data transmission method based on digital mixing for combining multiple inputs channels into a single output. We first demonstrate that the sources of the error generated in the output stream are the frequency ratio of the input signals and their relative phase shift. With the results from the simulations, we demonstrate that the error performed on the lower frequency information in the mixed signal has a trend which is exponentially decreasing with the input frequency ratio. Additionally, we prove that the relative phase shift of the input signals may significantly impact the error towards lower input frequency ratios. Afterwards, we analyze the system power consumption, and we demonstrate that the power trend is linear with the input frequency ratio. Lastly, we discuss the error performance versus power trade-off of the system, which is helpful for the design of the input frequency levels for a specific target application.
物联网(IoT)范式彻底改变了人类健康监测领域。最近的研究工作概述了对小型化全功能设备开发的日益增长的兴趣,其中在尺寸,功耗和数据传输能力方面的优化策略代表了设计阶段的主要要求和最大挑战。本文分析了一种基于数字混频的数据传输方法,将多个输入通道合并为一个输出通道。我们首先证明了输出流中产生的误差的来源是输入信号的频率比和它们的相对相移。仿真结果表明,混合信号中低频信息的误差随输入频率比的增大呈指数减小的趋势。此外,我们证明了输入信号的相对相移可能会显著影响较低输入频率比的误差。然后,我们分析了系统功耗,并证明了功率趋势与输入频率比呈线性关系。最后,我们讨论了系统的误差性能与功率权衡,这有助于设计特定目标应用的输入频率电平。
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引用次数: 0
Equivalent Circuit Analysis of CMUTs-based Device for Measurement in Liquid Samples 基于cmuts的液体样品测量装置的等效电路分析
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478722
Yihe Zhao, Libo Zhao, Gian Luca Barbruni, Zhikang Li, Zhuangde Jiang, S. Carrara
Capacitive micromachined ultrasonic transducers (CMUTs) operating at the series and parallel resonant frequencies, have shown a great potential in ultrasonic application and in biodetection. However, previous equivalent circuits rarely consider the fitting performance and measurement. This study proposes the establishment of the simplified equivalent circuits for the CMUTs-based device to analyze the electrical properties and the measurement sensitivity in liquid environment. We simulate a circular CMUT cell both in air and water through finite element method via COMSOL software, exploiting the multi-domain coupling method. We analyze the impedance behaviors of the CMUTs array with 100 cells under different direct current bias voltages (2 - 10V). Simultaneously, we successfully investigate the damping effects on the electrical characteristics such as impedance, phase, and quality factor. With the 4-element Butterworth-vanDyke model, two simplified equivalent lumped element models (LEMs) are demonstrated to fit the impedance curves of the CMUTs array around the series and parallel frequencies, respectively. Additionally, the sensitivity is evaluated using the simplified equivalent LEMs to explore the CMUTs array has a high normalized measurement sensitivity of 6.024 ppb/Hz at the parallel frequency.
电容式微机械超声换能器(CMUTs)工作在串联和并联谐振频率下,在超声和生物检测方面显示出巨大的应用潜力。然而,以往的等效电路很少考虑拟合性能和测量。本研究提出建立基于cmuts器件的简化等效电路,分析其在液体环境下的电学特性和测量灵敏度。利用COMSOL软件,利用多域耦合方法,对空气和水中的圆形CMUT单元进行了有限元模拟。在直流偏置电压(2 ~ 10V)不同的情况下,分析了100单元CMUTs阵列的阻抗行为。同时,我们成功地研究了阻尼对阻抗、相位和品质因子等电特性的影响。利用4元Butterworth-vanDyke模型,给出了两种简化的等效集总单元模型(lem),分别在串联和并联频率处拟合cmut阵列的阻抗曲线。此外,使用简化等效lem对灵敏度进行了评估,发现cmut阵列在并联频率下具有较高的归一化测量灵敏度,为6.024 ppb/Hz。
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引用次数: 1
期刊
2021 IEEE International Symposium on Medical Measurements and Applications (MeMeA)
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