Vaccine: X最新文献

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IF 2.2 Q3 IMMUNOLOGY

Vaccine: X

Pub Date : 2026-01-01

引用次数: 0

IF 2.2 Q3 IMMUNOLOGY

Vaccine: X

Pub Date : 2026-01-01

引用次数: 0

IF 2.2 Q3 IMMUNOLOGY

Vaccine: X

Pub Date : 2026-01-01

引用次数: 0

IF 2.2 Q3 IMMUNOLOGY

Vaccine: X

Pub Date : 2026-01-01

引用次数: 0

IF 2.2 Q3 IMMUNOLOGY

Vaccine: X

Pub Date : 2026-01-01

引用次数: 0

IF 2.2 Q3 IMMUNOLOGY

Vaccine: X

Pub Date : 2026-01-01

引用次数: 0

IF 2.2 Q3 IMMUNOLOGY

Vaccine: X

Pub Date : 2026-01-01

引用次数: 0

Determinants of incomplete vaccination against polio by 2 years of age in Canada: A cross-sectional study using the Childhood National Immunization Coverage Survey (CNICS) 加拿大2岁前脊髓灰质炎疫苗接种不完全的决定因素：使用儿童全国免疫覆盖调查（CNICS）的横断面研究

IF 2.2 Q3 IMMUNOLOGY

Vaccine: X

Pub Date : 2026-01-01 DOI: 10.1016/j.jvacx.2025.100768

Israa Zareef, Kristina Sabou, Anna Maria Frescura, Marwa Ebrahim, Julie Laroche

Background

Canada has not reached the national vaccination coverage goal of 95 % for polio vaccination in 2-year-old children. The objective of this study was to examine determinants of incomplete polio vaccination (receipt of less than 3 doses of a polio vaccine) by 2 years of age using data from the 2021 cycle of the Childhood National Immunization Coverage Survey (cNICS).

Methods

Simple and multiple logistic regression models were used to determine associations between sociodemographic factors of parents and children and knowledge, attitudes and beliefs of parents, relative to incomplete vaccination against polio among 2-year-old children.

Results

Incomplete polio vaccination by 2 years of age was associated with parents/guardians residing in Prairie provinces (AB, MB & SK) (aOR 2.2; 95 % CI: 1.3–3.6) or northern territories (NT, NU & YT) (aOR: 6.2; 95 % CI: 2.5–15.2) compared to central provinces (ON & QC); having a total 2020 household income of less than $60,000 CAD (aOR: 2.8; 95 % CI: 1.2–6.8) compared to $150,000 CAD and above; and living in a remote/very remote area (aOR: 4.7; 95 % CI: 1.8–12.4) compared to a more accessible area. Comparatively, parents/guardians were less likely to have children with incomplete polio vaccination if their child was indigenous (aOR: 0.1; 95 % CI: 0.1–0.3) compared to non-Indigenous and if they had a higher vaccine confidence score (OR: 0.3; 95 % CI: 0.2–0.4).

Conclusions

Future research should delve into barriers faced by parents/guardians to improve polio vaccine uptake through specific vaccine messaging and targeted programs.

加拿大尚未达到全国2岁儿童脊髓灰质炎疫苗接种覆盖率95%的目标。本研究的目的是利用2021年儿童全国免疫覆盖调查（cNICS）周期的数据，检查两岁前未接种脊髓灰质炎疫苗（接种少于3剂脊髓灰质炎疫苗）的决定因素。方法采用简单和多元logistic回归模型，确定父母和儿童的社会人口学因素与父母对2岁儿童脊髓灰质炎疫苗接种不完全的知识、态度和信念之间的关系。结果2岁前未完全接种脊髓灰质炎疫苗与父母/监护人居住在草原省份（AB, MB &； SK）（aOR: 2.2; 95% CI: 1.3-3.6）或北部地区（NT, NU &； YT）（aOR: 6.2; 95% CI: 2.5-15.2）与中部省份（ON &； QC）有关；2020年家庭总收入低于6万加元（aOR: 2.8; 95% CI: 1.2-6.8），而15万加元及以上；与更容易到达的地区相比，生活在偏远/非常偏远的地区（aOR: 4.7; 95% CI: 1.8-12.4）。相比之下，与非土著儿童相比，如果他们的孩子是土著儿童（aOR: 0.1; 95% CI: 0.1 - 0.3），并且如果他们的疫苗置信度评分较高（OR: 0.3; 95% CI: 0.2-0.4），那么他们的父母/监护人不太可能有未完全接种脊髓灰质炎疫苗的儿童。结论未来的研究应深入研究家长/监护人面临的障碍，通过特定的疫苗信息传递和有针对性的规划来提高脊髓灰质炎疫苗的摄取。

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引用次数: 0

Comparison of seasonal influenza vaccine hesitancy among young adults at a Hong Kong university before and after the start of the COVID-19 pandemic: A repeated cross-sectional study 2019冠状病毒病（COVID-19）大流行前后香港一所大学年轻人对季节性流感疫苗犹豫的比较：一项重复横断面研究

IF 2.2 Q3 IMMUNOLOGY

Vaccine: X

Pub Date : 2026-01-01 DOI: 10.1016/j.jvacx.2025.100774

Hongsen Liang , Fatema Khairunnasa , Hsiang-Yu Yuan

Background

Vaccine hesitancy (VH) among young adults limited seasonal influenza vaccine (SIV) uptake in Hong Kong. The impact of the COVID-19 pandemic on this issue remains unclear.

Methods

A repeated cross-sectional study was performed on 269 young adults aged 18 to 35 at a Hong Kong university during two seasons: pre-COVID-19 (September 30, 2019, to April 1, 2020, with 130 participants) and during-COVID-19 (March 29, 2021, to May 2, 2021, with 139 participants). We developed our questionnaire based on the Health Belief Model (HBM) and included peer influence. The best-fitting logistic regression model, selected using the chi-square test and Akaike Information Criterion (AIC), was used to assess the association between selected factors and VH in both periods.

Results

From the pre- to during-COVID-19 pandemic, the proportion of participants exhibiting vaccine hesitancy increased from 43.8 % to 62.6 %. Perceived vaccine side effects, vaccine efficacy, and peers' vaccination status became significant with odds ratios of 3.941 (95 % Confidence Interval (CI) [1.27, 14.36]), 0.1344 (95 % CI [0.02, 0.56]), and 0.1147 (95 % CI [0.02, 0.52]), respectively.

Conclusions

A comprehensive approach that includes effective communication about vaccine safety and efficacy is crucial. Additionally, the vaccination status of peers may play an important role in vaccine promotion among young adults in Hong Kong.

背景：香港年轻人的疫苗犹豫（VH）限制了季节性流感疫苗（SIV）的摄取。COVID-19大流行对这一问题的影响尚不清楚。方法对香港一所大学269名年龄在18至35岁之间的年轻人进行重复横断面研究，研究时间分为两个季节：2019年9月30日至2020年4月1日，130名参与者)和2019年3月29日至2021年5月2日，139名参与者。我们以健康信念模型（HBM）为基础开发问卷，并纳入同伴影响。采用卡方检验和赤池信息准则（Akaike Information Criterion， AIC）选择最佳拟合logistic回归模型，评估两个时期所选因素与VH之间的相关性。结果从covid -19大流行前到大流行期间，表现出疫苗犹豫的参与者比例从43.8%上升到62.6%。感知到的疫苗副作用、疫苗功效和同伴的接种状况变得显著，比值比分别为3.941（95%可信区间[1.27,14.36]）、0.1344 （95% CI[0.02, 0.56]）和0.1147 （95% CI[0.02, 0.52]）。结论采取包括疫苗安全性和有效性的有效沟通在内的综合措施至关重要。此外，同龄人的疫苗接种状况可能在香港年轻人的疫苗推广中发挥重要作用。

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IF 2.2 Q3 IMMUNOLOGY

Vaccine: X

Pub Date : 2026-01-01

引用次数: 0

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