Pub Date : 2023-11-01DOI: 10.22376/ijlpr.2023.13.6.p253-p276
Harsh Kumar Pandey, Anurag Kumar Yadav, Dr. Vimal Arora
Diabetes is a persistent metabolic condition that affects many individuals globally. To manage diabetes, patients need totake medication regularly, and the buccal patch has become a promising drug delivery option for this purpose. This review articlehighlights the potential of buccal patches as a novel approach to enhance patient compliance in treating diabetes mellitus. Byexploring the advantages of buccal patches as a non-invasive drug delivery system, this article emphasizes their potential to improvemedication adherence, thereby contributing to better management of diabetes mellitus. This article aims to evaluate the role ofbuccal patches in improving patient compliance in the treatment of diabetes mellitus. With the increasing global burden of diabetes,ensuring patient adherence to medication regimens is crucial for achieving optimal therapeutic outcomes. Traditional treatmentmethods often require frequent injections or oral administrations, which may lead to poor compliance due to various factors suchas fear of injections, inconvenience, or forgetfulness. Reviewing the literature on buccal patches as an alternative drug deliverysystem, this article explores their advantages in enhancing patient compliance. Buccal patches adhere to the inner lining of thecheek, providing a convenient and non-invasive route of drug administration. This approach eliminates the need for injections andreduces the frequency of oral medication intake, improving patient acceptance and adherence to treatment regimens. Furthermore,this article highlights the potential of buccal patches in delivering medications directly into the systemic circulation through thehighly vascularized oral mucosa. By bypassing first-pass metabolism in the liver, buccal patches can achieve higher drugconcentrations and improve therapeutic effects. Presenting the benefits of buccal patches for diabetes treatment encourages furtherresearch and development. So, the conclusion of this article is to promote awareness among healthcare professionals and patientsabout the potential of buccal patches as a patient-friendly approach to enhance compliance in the management of diabetes mellitus.
{"title":"Buccal Patch: A New Avenue for Better Patient Compliance in Management of Diabetes Mellitus","authors":"Harsh Kumar Pandey, Anurag Kumar Yadav, Dr. Vimal Arora","doi":"10.22376/ijlpr.2023.13.6.p253-p276","DOIUrl":"https://doi.org/10.22376/ijlpr.2023.13.6.p253-p276","url":null,"abstract":"Diabetes is a persistent metabolic condition that affects many individuals globally. To manage diabetes, patients need totake medication regularly, and the buccal patch has become a promising drug delivery option for this purpose. This review articlehighlights the potential of buccal patches as a novel approach to enhance patient compliance in treating diabetes mellitus. Byexploring the advantages of buccal patches as a non-invasive drug delivery system, this article emphasizes their potential to improvemedication adherence, thereby contributing to better management of diabetes mellitus. This article aims to evaluate the role ofbuccal patches in improving patient compliance in the treatment of diabetes mellitus. With the increasing global burden of diabetes,ensuring patient adherence to medication regimens is crucial for achieving optimal therapeutic outcomes. Traditional treatmentmethods often require frequent injections or oral administrations, which may lead to poor compliance due to various factors suchas fear of injections, inconvenience, or forgetfulness. Reviewing the literature on buccal patches as an alternative drug deliverysystem, this article explores their advantages in enhancing patient compliance. Buccal patches adhere to the inner lining of thecheek, providing a convenient and non-invasive route of drug administration. This approach eliminates the need for injections andreduces the frequency of oral medication intake, improving patient acceptance and adherence to treatment regimens. Furthermore,this article highlights the potential of buccal patches in delivering medications directly into the systemic circulation through thehighly vascularized oral mucosa. By bypassing first-pass metabolism in the liver, buccal patches can achieve higher drugconcentrations and improve therapeutic effects. Presenting the benefits of buccal patches for diabetes treatment encourages furtherresearch and development. So, the conclusion of this article is to promote awareness among healthcare professionals and patientsabout the potential of buccal patches as a patient-friendly approach to enhance compliance in the management of diabetes mellitus.","PeriodicalId":44665,"journal":{"name":"International Journal of Life Science and Pharma Research","volume":"54 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135454968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-01DOI: 10.22376/ijlpr.2023.13.6.l557-l561
Pavani Reddy, Ganesh C
Our study aim is to characterize and assess the case of Stomatitis medicamentosa in a patient who developed manyoral ulcers after using Carbamazepine for the treatment of Trigeminal Neuralgia of a 35-year-old female patient with a medicalhistory of hypertension for the past ten years and under medication. The patient also gave a history of electric shock-like painon the left side of the face for the past month and was prescribed Tegretol 100mg (Carbamazepine) twice daily. After taking thismedication, the patient suffered several mouth ulcers. The patient was asked to stop taking this medication and asked to takeoral antihistamines and systemic Gabapentin steroids for one month. After one week, the patient heals completely from thelesions. Burning sensation with altered taste sensation and difficulty while swallowing are common patient complaints. Mouthopening was restricted and painful. The skin test (prick test) is done, which shows red, papular, or vesicular reactions. Earlyidentification of the lesion and prompt withdrawal of the offending drug are key for successful management, and the drug can bereplaced with another drug of the same efficacy. Thus, adverse drug reactions can be minimised by asking the patient aboutallergy to any drug or food while writing a prescription, and the patient should be informed and familiarised with the drugpatient the patient is allergic.
{"title":"Case Study of Stomatitis Medicamentosa Due to Trigeminal Neuralgia Medication","authors":"Pavani Reddy, Ganesh C","doi":"10.22376/ijlpr.2023.13.6.l557-l561","DOIUrl":"https://doi.org/10.22376/ijlpr.2023.13.6.l557-l561","url":null,"abstract":"Our study aim is to characterize and assess the case of Stomatitis medicamentosa in a patient who developed manyoral ulcers after using Carbamazepine for the treatment of Trigeminal Neuralgia of a 35-year-old female patient with a medicalhistory of hypertension for the past ten years and under medication. The patient also gave a history of electric shock-like painon the left side of the face for the past month and was prescribed Tegretol 100mg (Carbamazepine) twice daily. After taking thismedication, the patient suffered several mouth ulcers. The patient was asked to stop taking this medication and asked to takeoral antihistamines and systemic Gabapentin steroids for one month. After one week, the patient heals completely from thelesions. Burning sensation with altered taste sensation and difficulty while swallowing are common patient complaints. Mouthopening was restricted and painful. The skin test (prick test) is done, which shows red, papular, or vesicular reactions. Earlyidentification of the lesion and prompt withdrawal of the offending drug are key for successful management, and the drug can bereplaced with another drug of the same efficacy. Thus, adverse drug reactions can be minimised by asking the patient aboutallergy to any drug or food while writing a prescription, and the patient should be informed and familiarised with the drugpatient the patient is allergic.","PeriodicalId":44665,"journal":{"name":"International Journal of Life Science and Pharma Research","volume":"8 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135764220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-24DOI: 10.22376/ijlpr.2023.13.6.l115-l121
H. M. Hanumantha Rao, L. Rajanna
: Many studies confirmed that degenerate primers LM638 and LM637 amplify NBS-LRR Type R gene encoding sequences in both monocots and dicots. In addition, these primers also amplify nonspecific multiple bands along with specific amplification. The current study aims to explore the structure, role and reason for nonspecific bands in the amplification. The genomic DNA-degenerate PCR method was used to isolate the NBS-LRR type R-genes in Drimia species (synonym Urginea). Agarose gel electrophoresis was carried out for separation and visualization of amplified bands. The kit-based gel extraction method was followed to purify the PCR bands. Purified PCR bands were subjected to TA cloning. The plasmids which contain desired PCR bands were sequenced using the Sanger sequencing method. Multiple sequence alignment tool CLUSTALW was used to align sequences and MISA-Web tool was used to identify simple sequence repeats (SSR). The results of the study revealed that multiple sequence analysis of PCR bands of 600bp/500bp showed random deletions, presence of indels and frameshift mutations in the alignment. The sequence alignment also showed monomorphic sites between two sequences. Both 600 and 500bp were devoid of simple sequence repeats and the ORF finder confirmed the presence of irregular stop codons in the 600 bp sequences. The multiple sequence alignment tool was used in disclosing the structure and ancestor relationship between aligned Drimia sequences. The current study would help to explore pseudo genes in the genome of Drimia and to differentiate the orthologous and paralogous relationships in the sequences.
{"title":"Analysis of Multiple PCR Bands in Drimia Species Obtained by R-Gene Specific Degenerate Primers","authors":"H. M. Hanumantha Rao, L. Rajanna","doi":"10.22376/ijlpr.2023.13.6.l115-l121","DOIUrl":"https://doi.org/10.22376/ijlpr.2023.13.6.l115-l121","url":null,"abstract":": Many studies confirmed that degenerate primers LM638 and LM637 amplify NBS-LRR Type R gene encoding sequences in both monocots and dicots. In addition, these primers also amplify nonspecific multiple bands along with specific amplification. The current study aims to explore the structure, role and reason for nonspecific bands in the amplification. The genomic DNA-degenerate PCR method was used to isolate the NBS-LRR type R-genes in Drimia species (synonym Urginea). Agarose gel electrophoresis was carried out for separation and visualization of amplified bands. The kit-based gel extraction method was followed to purify the PCR bands. Purified PCR bands were subjected to TA cloning. The plasmids which contain desired PCR bands were sequenced using the Sanger sequencing method. Multiple sequence alignment tool CLUSTALW was used to align sequences and MISA-Web tool was used to identify simple sequence repeats (SSR). The results of the study revealed that multiple sequence analysis of PCR bands of 600bp/500bp showed random deletions, presence of indels and frameshift mutations in the alignment. The sequence alignment also showed monomorphic sites between two sequences. Both 600 and 500bp were devoid of simple sequence repeats and the ORF finder confirmed the presence of irregular stop codons in the 600 bp sequences. The multiple sequence alignment tool was used in disclosing the structure and ancestor relationship between aligned Drimia sequences. The current study would help to explore pseudo genes in the genome of Drimia and to differentiate the orthologous and paralogous relationships in the sequences.","PeriodicalId":44665,"journal":{"name":"International Journal of Life Science and Pharma Research","volume":"2 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135220102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-06DOI: 10.22376/ijlpr.2023.13.6.l153-l157
Dr. Vidhya Selvam, Dr. C. Minu Priya
Gynecologists who treat endometriosis, a chronic, disabling disease, face difficulties diagnosing and treating the condition. Endometriotic cyst, with internal septations and opacities sonologically, mimics malignancy. Increased levels of CA 125 Are used as a tumor marker in epithelial ovarian malignancies. It is also an important prognostic indicator and follow-up tool in managing ovarian malignancies. A moderate increase in CA125 levels is observed in physiological conditions like ovulation and benign conditions like endometriosis and PID. We present here a case of extremely elevated serum CA 125 level in a patient who presented with recurrent ovarian endometriosis. Mrs. X, 46 years old, presented with a complex ovarian cyst with CA 125 level- 1021 iu/ml. With a history of laparotomy for endometriotic cysts in the past. Intraoperatively bilateral complex ovarian cysts were identified, which were densely adherent to the lateral pelvic wall and rectum posteriorly. The ovarian cysts were excised with a hysterectomy. The Patient developed dribbling of urine on the third postoperative day. CT urogram revealed a right ureterovaginal fistula. Laparotomy done. Uretero ureteral anastomosis done by a urologist. The Postoperative patient remained dry. Histopathological evaluation revealed benign endometriosis. Extensive and aggressive surgeries are usually done for ovarian malignancies to provide optimal reduction. However, in our patient, risk assessment for malignancy based on radiological factors and tumor markers was highly suggestive of malignancy. Yet, the histopathology turned out to be benign endometriosis. Therefore, to avoid invasive investigations and surgeries associated with high morbidity, emphasis must be made on the possibility of raised CA 125 levels in benign conditions such as endometriosis.
{"title":"Recurrent Endometriotic Cyst with High Ca-125 Level Mimicking Malignancy","authors":"Dr. Vidhya Selvam, Dr. C. Minu Priya","doi":"10.22376/ijlpr.2023.13.6.l153-l157","DOIUrl":"https://doi.org/10.22376/ijlpr.2023.13.6.l153-l157","url":null,"abstract":"Gynecologists who treat endometriosis, a chronic, disabling disease, face difficulties diagnosing and treating the condition. Endometriotic cyst, with internal septations and opacities sonologically, mimics malignancy. Increased levels of CA 125 Are used as a tumor marker in epithelial ovarian malignancies. It is also an important prognostic indicator and follow-up tool in managing ovarian malignancies. A moderate increase in CA125 levels is observed in physiological conditions like ovulation and benign conditions like endometriosis and PID. We present here a case of extremely elevated serum CA 125 level in a patient who presented with recurrent ovarian endometriosis. Mrs. X, 46 years old, presented with a complex ovarian cyst with CA 125 level- 1021 iu/ml. With a history of laparotomy for endometriotic cysts in the past. Intraoperatively bilateral complex ovarian cysts were identified, which were densely adherent to the lateral pelvic wall and rectum posteriorly. The ovarian cysts were excised with a hysterectomy. The Patient developed dribbling of urine on the third postoperative day. CT urogram revealed a right ureterovaginal fistula. Laparotomy done. Uretero ureteral anastomosis done by a urologist. The Postoperative patient remained dry. Histopathological evaluation revealed benign endometriosis. Extensive and aggressive surgeries are usually done for ovarian malignancies to provide optimal reduction. However, in our patient, risk assessment for malignancy based on radiological factors and tumor markers was highly suggestive of malignancy. Yet, the histopathology turned out to be benign endometriosis. Therefore, to avoid invasive investigations and surgeries associated with high morbidity, emphasis must be made on the possibility of raised CA 125 levels in benign conditions such as endometriosis.","PeriodicalId":44665,"journal":{"name":"International Journal of Life Science and Pharma Research","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45360273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-06DOI: 10.22376/ijlpr.2023.13.6.l186-l192
Dr Prasad Gajanan Yewale, Dr. Renu Rathi, Dr. Swapnali Mate, Dr. Ankush Dikondwar
11-year-old male patient brought by relatives in Kaumarbhritya OPD with complaints of spending excessive time on smartphones andcomputers with changes in the patient's behavior since 1 year. Relatives counseled the patient, but he didn't change his behavior. Previous Doctorsadvised Cognitive behavioral therapy, but that facility was not available at their place, and the parents could not afford it. Hence they came toAyurveda Hospital. The patient is assessed using the Internet addiction test scale and DSM-V scale for social behavior. The patient is diagnosed as acase of Gadget addiction (internet addiction) with abnormal social behavior. After proper physical examinations, the patient is counseled inexplaining the hazardous effects of excessive use of gadgets; along with this, he is advised daily Suryanamskara, &Dhyana(meditation) as a Yogaintervention. The patient was advised to play outdoor games daily, and his gadgets using time were reduced by systematic order. Parents wereadvised to be patient in family functions and social meetings & to spend time with children. All the training regarding intervention is given in PPTformat to the patient. The patient was asked to perform Suryanamaskara on follow-up days. On the 91st day, the patient was reassessed using theInternet addiction test scale and DSM-V scale for social behavior, which were normal. Gadget addiction is a common behavioral problem inchildren. Online gaming, gambling, excessive web browsing, and social media use are all included under the umbrella term "gadget addiction.". Evenif there is treatment for gadget addiction, people in remote areas may find it inconvenient due to a lack of infrastructure and specialized pediatricpsychologists. Hence, finding an effective and convenient treatment for Gadget addiction is necessary. This study aims to assess the efficacy ofAyurvedic management in Gadget addiction based on Ayurveda Non-pharmacological intervention. Any addiction results from bad decision-makingcapacity and less control over the mind. The intervention in this study, like Yoga, satvavajaya, proves beneficial to the patient.
{"title":"Management of Gadget Addiction Through Ayurveda in Pediatric Patient: A Single Case Study","authors":"Dr Prasad Gajanan Yewale, Dr. Renu Rathi, Dr. Swapnali Mate, Dr. Ankush Dikondwar","doi":"10.22376/ijlpr.2023.13.6.l186-l192","DOIUrl":"https://doi.org/10.22376/ijlpr.2023.13.6.l186-l192","url":null,"abstract":"11-year-old male patient brought by relatives in Kaumarbhritya OPD with complaints of spending excessive time on smartphones andcomputers with changes in the patient's behavior since 1 year. Relatives counseled the patient, but he didn't change his behavior. Previous Doctorsadvised Cognitive behavioral therapy, but that facility was not available at their place, and the parents could not afford it. Hence they came toAyurveda Hospital. The patient is assessed using the Internet addiction test scale and DSM-V scale for social behavior. The patient is diagnosed as acase of Gadget addiction (internet addiction) with abnormal social behavior. After proper physical examinations, the patient is counseled inexplaining the hazardous effects of excessive use of gadgets; along with this, he is advised daily Suryanamskara, &Dhyana(meditation) as a Yogaintervention. The patient was advised to play outdoor games daily, and his gadgets using time were reduced by systematic order. Parents wereadvised to be patient in family functions and social meetings & to spend time with children. All the training regarding intervention is given in PPTformat to the patient. The patient was asked to perform Suryanamaskara on follow-up days. On the 91st day, the patient was reassessed using theInternet addiction test scale and DSM-V scale for social behavior, which were normal. Gadget addiction is a common behavioral problem inchildren. Online gaming, gambling, excessive web browsing, and social media use are all included under the umbrella term \"gadget addiction.\". Evenif there is treatment for gadget addiction, people in remote areas may find it inconvenient due to a lack of infrastructure and specialized pediatricpsychologists. Hence, finding an effective and convenient treatment for Gadget addiction is necessary. This study aims to assess the efficacy ofAyurvedic management in Gadget addiction based on Ayurveda Non-pharmacological intervention. Any addiction results from bad decision-makingcapacity and less control over the mind. The intervention in this study, like Yoga, satvavajaya, proves beneficial to the patient.","PeriodicalId":44665,"journal":{"name":"International Journal of Life Science and Pharma Research","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135204810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gastrointestinal parasites play crucial roles in mortality and morbidity. They are most prevalent in rural areas. Parasitosis affects all age groups. Inchildren, it causes slow mental and physical growth, produces long-term effects, leads to a deficiency of vital nutrients, and hampers growth and development.This prospective study aimed to assess the prevalence of gastrointestinal parasitosis in stool samples among the people of Uttarakhand, especially of Dehradun,from January 2017 to January 2018. To identify intestinal parasites, 1528 samples were examined for consistency and the presence of any parasitic particlesusing the visual, direct wet mount, and concentration methods. The SPSS statistical program was used to conduct the statistical analysis. Differences with a pvalueof less than 0.05 were considered significant. The overall prevalence of intestinal parasitic infection rate was 32.85%. The prevalence of the parasites wasin the following order - Giardia lamblia (29.48%), Entamoeba histolytica (20.91%), Ascaris lumbricoides (18.52%), Hymenolepis nana (7.96%), Trichuris trichiura(7.56%), Taenia sp. (7.17%), Strongyloides stercoralis (5.97%), Ancylostoma duodenale (2.19%), and Enterobius vermicularis (0.19%). The chi-square test (χ2 – 30 andP-value = 0.224) was insignificant, while Levene’s test was significant (F = 10.08, P-value = 0.008) of A. duodenale in both genders. Parasitosis of high levels wasdetected among the children. Health education, personal hygiene, and safe drinking water would reduce infection. However, designing specific controlmeasures requires proper identification. The present study may prove helpful for developing such measures for Uttarakhand in general and Dehradun inparticular.
{"title":"Prevalence and Epidemiology of Gastrointestinal Parasitosis Among the People of Dehradun, Uttarakhand","authors":"Ashok Kumar Sah, Ankur Vashishtha, Jesbin Johnson, Kajal Arora, Pankaj Issar, Rohit Rathore, Ritam Koley, Suresh Jaiswal, Farhana Zahir, Mohammad Mahamood","doi":"10.22376/ijlpr.2023.13.6.l22-l31","DOIUrl":"https://doi.org/10.22376/ijlpr.2023.13.6.l22-l31","url":null,"abstract":"Gastrointestinal parasites play crucial roles in mortality and morbidity. They are most prevalent in rural areas. Parasitosis affects all age groups. Inchildren, it causes slow mental and physical growth, produces long-term effects, leads to a deficiency of vital nutrients, and hampers growth and development.This prospective study aimed to assess the prevalence of gastrointestinal parasitosis in stool samples among the people of Uttarakhand, especially of Dehradun,from January 2017 to January 2018. To identify intestinal parasites, 1528 samples were examined for consistency and the presence of any parasitic particlesusing the visual, direct wet mount, and concentration methods. The SPSS statistical program was used to conduct the statistical analysis. Differences with a pvalueof less than 0.05 were considered significant. The overall prevalence of intestinal parasitic infection rate was 32.85%. The prevalence of the parasites wasin the following order - Giardia lamblia (29.48%), Entamoeba histolytica (20.91%), Ascaris lumbricoides (18.52%), Hymenolepis nana (7.96%), Trichuris trichiura(7.56%), Taenia sp. (7.17%), Strongyloides stercoralis (5.97%), Ancylostoma duodenale (2.19%), and Enterobius vermicularis (0.19%). The chi-square test (χ2 – 30 andP-value = 0.224) was insignificant, while Levene’s test was significant (F = 10.08, P-value = 0.008) of A. duodenale in both genders. Parasitosis of high levels wasdetected among the children. Health education, personal hygiene, and safe drinking water would reduce infection. However, designing specific controlmeasures requires proper identification. The present study may prove helpful for developing such measures for Uttarakhand in general and Dehradun inparticular.","PeriodicalId":44665,"journal":{"name":"International Journal of Life Science and Pharma Research","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135204455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-06DOI: 10.22376/ijlpr.2023.13.6.l272-l279
Dr.Shruti Kapatkar, Dr. Renu Rathi, Dr Trupti Thakre, Dr.Manisha Panda
In Ksheerapa avastha, kukunaka is a specific inflammatory eye illness that most commonly affects infants under eight months.Kukunaka is mentioned as Vartmagata Kapha-Raktaj disease of eye. It is a Bala Netrarog linked to photophobia and ocular weakening.The most prevalent eye condition affecting infants is kukunaka, associated with neonatal conjunctivitis or Ophthalmia neonatorum.Local irritation, microorganisms, and the herpes simplex virus are the main causes of inflammation. It happens due to postpartumdifficulties or infections and maternal infections during labor and delivery. Because of an allergic reaction, the child keeps rubbing theirforehead, eyes, nose, and throat. This condition is characterized by watering and purulent discharge from both eyes and keratitis oruveitis may also be present. A neonate with neonatal conjunctivitis or ophthalmia neonatorum would have an inflamed conjunctiva.This review paper aims to review the management of Kukunaka from classical texts of Ayurveda. This review was conducted by learningAyurveda classical texts related to Kaumarbhrutya, Pediatrics texts on Neonatal diseases, published research journals on Pediatricdiseases, and electronic databases. This review's peculiarity is compiling all the data for kukunaka vyadhi from classic texts like its clinicalfeatures, causative factors, and various internal and external medications. Various formulations of kukunaka that are not studied yet areenlightened in this review, along with some shodhana karma that was indicated to nursing mothers and infants, are described in detail.The article concludes that this review is carried out for future research, which will be helpful for the management of kukunaka.
{"title":"A Critical Review On the Management of Kukunaka with Special Reference to Neonatal Conjunctivitis","authors":"Dr.Shruti Kapatkar, Dr. Renu Rathi, Dr Trupti Thakre, Dr.Manisha Panda","doi":"10.22376/ijlpr.2023.13.6.l272-l279","DOIUrl":"https://doi.org/10.22376/ijlpr.2023.13.6.l272-l279","url":null,"abstract":"In Ksheerapa avastha, kukunaka is a specific inflammatory eye illness that most commonly affects infants under eight months.Kukunaka is mentioned as Vartmagata Kapha-Raktaj disease of eye. It is a Bala Netrarog linked to photophobia and ocular weakening.The most prevalent eye condition affecting infants is kukunaka, associated with neonatal conjunctivitis or Ophthalmia neonatorum.Local irritation, microorganisms, and the herpes simplex virus are the main causes of inflammation. It happens due to postpartumdifficulties or infections and maternal infections during labor and delivery. Because of an allergic reaction, the child keeps rubbing theirforehead, eyes, nose, and throat. This condition is characterized by watering and purulent discharge from both eyes and keratitis oruveitis may also be present. A neonate with neonatal conjunctivitis or ophthalmia neonatorum would have an inflamed conjunctiva.This review paper aims to review the management of Kukunaka from classical texts of Ayurveda. This review was conducted by learningAyurveda classical texts related to Kaumarbhrutya, Pediatrics texts on Neonatal diseases, published research journals on Pediatricdiseases, and electronic databases. This review's peculiarity is compiling all the data for kukunaka vyadhi from classic texts like its clinicalfeatures, causative factors, and various internal and external medications. Various formulations of kukunaka that are not studied yet areenlightened in this review, along with some shodhana karma that was indicated to nursing mothers and infants, are described in detail.The article concludes that this review is carried out for future research, which will be helpful for the management of kukunaka.","PeriodicalId":44665,"journal":{"name":"International Journal of Life Science and Pharma Research","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135204809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-06DOI: 10.22376/ijlpr.2023.13.6.l92-l103
Dr. Jagruti Chaple, D. Sawarkar, Dr. Dhirajsingh S. Rajput
A village-level community health worker, an "Accredited Social Health Activist " (ASHA), bridges community and healthcare facilities. The ASHA workers act as catalysts in promoting various foundation programs and encourage people to avail the available benefits. The study aimed to assess knowledge of Panchakarma in ASHA Workers & Sensitization with the Panchakarma module in Wardha taluka. The study's objectives include designing a Panchakarma questionnaire module to assess the knowledge and awareness of ASHA workers of Wardha Taluka and sensitizing ASHA workers about Panchakarma procedures with the help of demonstration videos and lectures on Panchakarma. The work was planned to be conducted at Anji and Waifad villages under Wardha taluka. A questionnaire consisting of 30 questions was prepared to assess the knowledge, awareness, and attitudes regarding Panchakarma. Panchakarma's knowledge, awareness, and attitudes were analyzed using pre-and post-test scores. ASHA will be a facilitator for promoting awareness in the community about Panchakarma. The study concluded that the intervention of the Panchakarma module was highly influential in enhancing knowledge about Panchakarma among ASHA workers. In the future, this Panchakarma module will enable people in the community to accept the Panchakarma therapy in Ayurveda. ASHA will provide more referral services of panchakarma therapy to patients by encouraging them to undergo these therapies. It was the first footstep in developing the module on awareness regarding Panchakarma therapy to enrich the knowledge of ASHA workers as per their needs and implementation of this module by the ASHA in the community.
{"title":"Sensitization and Assessment of Knowledge of Ayurveda Panchakarma Therapy Among ASHA Workers in Wardha Taluka","authors":"Dr. Jagruti Chaple, D. Sawarkar, Dr. Dhirajsingh S. Rajput","doi":"10.22376/ijlpr.2023.13.6.l92-l103","DOIUrl":"https://doi.org/10.22376/ijlpr.2023.13.6.l92-l103","url":null,"abstract":"A village-level community health worker, an \"Accredited Social Health Activist \" (ASHA), bridges community and healthcare facilities. The ASHA workers act as catalysts in promoting various foundation programs and encourage people to avail the available benefits. The study aimed to assess knowledge of Panchakarma in ASHA Workers & Sensitization with the Panchakarma module in Wardha taluka. The study's objectives include designing a Panchakarma questionnaire module to assess the knowledge and awareness of ASHA workers of Wardha Taluka and sensitizing ASHA workers about Panchakarma procedures with the help of demonstration videos and lectures on Panchakarma. The work was planned to be conducted at Anji and Waifad villages under Wardha taluka. A questionnaire consisting of 30 questions was prepared to assess the knowledge, awareness, and attitudes regarding Panchakarma. Panchakarma's knowledge, awareness, and attitudes were analyzed using pre-and post-test scores. ASHA will be a facilitator for promoting awareness in the community about Panchakarma. The study concluded that the intervention of the Panchakarma module was highly influential in enhancing knowledge about Panchakarma among ASHA workers. In the future, this Panchakarma module will enable people in the community to accept the Panchakarma therapy in Ayurveda. ASHA will provide more referral services of panchakarma therapy to patients by encouraging them to undergo these therapies. It was the first footstep in developing the module on awareness regarding Panchakarma therapy to enrich the knowledge of ASHA workers as per their needs and implementation of this module by the ASHA in the community.","PeriodicalId":44665,"journal":{"name":"International Journal of Life Science and Pharma Research","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48698000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
An unfavorable sensory or emotional encounter connected to actual or potential tissue injury is referred to as neck pain, and it affects the region of the neck between the superior nuchal line and the first thoracic spinous process. Mechanical neck pain often commences insidiously and is of multifactorial etiology, causing disability and clinical symptoms. It is a comparative study where 30 male and female subjects were assessed and identified with Mechanical Neck Pain, recruited for the study, and randomly divided into two groups with 15 subjects in each group. Outcome measures were the Visual Analogue Scale (VAS), goniometer, and neck disability index (NDI). Pre-Test and Post-Test were carried out for both groups and analyzed using paired 't-tests and independent 't-tests in an IBM SPSS statistics 26 software. This study aimed to compare the effectiveness of muscle energy technique with conventional therapy vs. kinesio taping with conventional therapy in chronic mechanical neck pain, cervical range of motion, and functional disability of the neck. KT provides sensory feedback, tension, and afferent stimulation to reduce pain and improve ROM. It also helps in lymphatic and vascular flow and corrects misaligned structures. Muscle energy technique and Kinesio taping showed significant improvement in VAS, Goniometer, and NDI in mechanical neck pain patients, making them suitable for inclusion in mechanical neck pain treatment.
{"title":"Muscle Energy Technique Effects On Pain, Cervical Range of Motion, and Functional Disability","authors":"Ayang Kino, Abhijit Dutta, Pompy Mahato, Abhijit Kalita","doi":"10.22376/ijlpr.2023.13.6.l158-l170","DOIUrl":"https://doi.org/10.22376/ijlpr.2023.13.6.l158-l170","url":null,"abstract":"An unfavorable sensory or emotional encounter connected to actual or potential tissue injury is referred to as neck pain, and it affects the region of the neck between the superior nuchal line and the first thoracic spinous process. Mechanical neck pain often commences insidiously and is of multifactorial etiology, causing disability and clinical symptoms. It is a comparative study where 30 male and female subjects were assessed and identified with Mechanical Neck Pain, recruited for the study, and randomly divided into two groups with 15 subjects in each group. Outcome measures were the Visual Analogue Scale (VAS), goniometer, and neck disability index (NDI). Pre-Test and Post-Test were carried out for both groups and analyzed using paired 't-tests and independent 't-tests in an IBM SPSS statistics 26 software. This study aimed to compare the effectiveness of muscle energy technique with conventional therapy vs. kinesio taping with conventional therapy in chronic mechanical neck pain, cervical range of motion, and functional disability of the neck. KT provides sensory feedback, tension, and afferent stimulation to reduce pain and improve ROM. It also helps in lymphatic and vascular flow and corrects misaligned structures. Muscle energy technique and Kinesio taping showed significant improvement in VAS, Goniometer, and NDI in mechanical neck pain patients, making them suitable for inclusion in mechanical neck pain treatment.","PeriodicalId":44665,"journal":{"name":"International Journal of Life Science and Pharma Research","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49537228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
During the COVID-19 pandemic, people hesitate to visit hospitals for consultation, treatment, and follow-up. Theavailability of advanced technologies, like teleconsultation, helps people continue their access to healthcare, consult doctors fortheir symptoms, and get treated. Few studies have been done in Tamilnadu to assess people's experience in accessing healthcarethrough a teleconsultation approach. As the pandemic is ongoing, it is imperative to assess the quality of healthcare and patientsatisfaction with teleconsultation services. With the above background, this study was done to assess the patient's experience inthe use of teleconsultation during the COVID-19 pandemic in Chennai, Tamilnadu. The study's objectives were to determine theattitude towards the use of teleconsultation and to describe the quality of healthcare provided through this method. This studywas done among residents in the city of Chennai, Tamilnadu. Individuals aged 18 years and above, residing in Chennai, and had atleast one teleconsultation during the COVID-19 pandemic were included. Data were collected by an online, self-administeredquestionnaire disseminated through various social media platforms. Data were entered in Microsoft Excel and analyzed in Epiinfo. Among 405 study respondents, 61.2% were males. The mean age of the respondents was 34.6 years. Nearly 95.6% agreedthat teleconsultation services have made access to healthcare easier during the pandemic. Around 92.1% were satisfied with thequality of healthcare through teleconsultation. About 55.3% said they paid more for online consultation when compared todirect consultation. Among 92.6% of participants who were advised a follow-up consultation, only 52% completed the follow-up.About 90% still preferred direct consultation with healthcare providers in the future. Though many participants felt thatteleconsultation services improved access to healthcare during the pandemic, they still wished to contact healthcare providersdirectly in the future.
{"title":"Teleconsultation During COVID-19 Pandemic in Chennai, India: A Cross- Sectional Study","authors":"Angeline Grace G, Swetha NB, Rashmi Gour, Umadevi R, Sujitha P","doi":"10.22376/ijlpr.2023.13.6.l193-l204","DOIUrl":"https://doi.org/10.22376/ijlpr.2023.13.6.l193-l204","url":null,"abstract":"During the COVID-19 pandemic, people hesitate to visit hospitals for consultation, treatment, and follow-up. Theavailability of advanced technologies, like teleconsultation, helps people continue their access to healthcare, consult doctors fortheir symptoms, and get treated. Few studies have been done in Tamilnadu to assess people's experience in accessing healthcarethrough a teleconsultation approach. As the pandemic is ongoing, it is imperative to assess the quality of healthcare and patientsatisfaction with teleconsultation services. With the above background, this study was done to assess the patient's experience inthe use of teleconsultation during the COVID-19 pandemic in Chennai, Tamilnadu. The study's objectives were to determine theattitude towards the use of teleconsultation and to describe the quality of healthcare provided through this method. This studywas done among residents in the city of Chennai, Tamilnadu. Individuals aged 18 years and above, residing in Chennai, and had atleast one teleconsultation during the COVID-19 pandemic were included. Data were collected by an online, self-administeredquestionnaire disseminated through various social media platforms. Data were entered in Microsoft Excel and analyzed in Epiinfo. Among 405 study respondents, 61.2% were males. The mean age of the respondents was 34.6 years. Nearly 95.6% agreedthat teleconsultation services have made access to healthcare easier during the pandemic. Around 92.1% were satisfied with thequality of healthcare through teleconsultation. About 55.3% said they paid more for online consultation when compared todirect consultation. Among 92.6% of participants who were advised a follow-up consultation, only 52% completed the follow-up.About 90% still preferred direct consultation with healthcare providers in the future. Though many participants felt thatteleconsultation services improved access to healthcare during the pandemic, they still wished to contact healthcare providersdirectly in the future.","PeriodicalId":44665,"journal":{"name":"International Journal of Life Science and Pharma Research","volume":"248 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135203929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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