Maha A Alanazi, F. Alzahrani, S. Shaikh, Amir H Msmar, F. Hassan
Introduction: B-acute lymphoblastic leukemia (B-ALL) is a malignant neoplasm of hematopoietic stem cells originating in bone marrow and characterized by proliferation of blast cells of lymphoid series. The aim of this study was to predictive scoring system (SS) using a fully standardized EuroFlow eight-color panel. Methods: The expression of the different cluster of differentiation (CD) markers involved in the B-ALL EuroFlow panel was investigated by measuring their positivity, percentage, and median fluorescence intensity. Results: CD9, CD123, and TdT were used to predict TCF3PBX1 with 80.0% sensitivity (SN) and 100% specificity (SP). CD20 and CD66 were used to predict hypoploidy with 63.0% SN and 100% SP. As a result, no useful discriminative SS was developed. Conclusions: Four SSs were proposed for the prediction of the most common cytogenetic abnormalities of Saudi B-ALL.
{"title":"Common genetic abnormalities and phenotypic scoring in Saudi patients with acute B-lymphoblastic leukemia","authors":"Maha A Alanazi, F. Alzahrani, S. Shaikh, Amir H Msmar, F. Hassan","doi":"10.29333/ejgm/13537","DOIUrl":"https://doi.org/10.29333/ejgm/13537","url":null,"abstract":"Introduction: B-acute lymphoblastic leukemia (B-ALL) is a malignant neoplasm of hematopoietic stem cells originating in bone marrow and characterized by proliferation of blast cells of lymphoid series. The aim of this study was to predictive scoring system (SS) using a fully standardized EuroFlow eight-color panel.\u0000Methods: The expression of the different cluster of differentiation (CD) markers involved in the B-ALL EuroFlow panel was investigated by measuring their positivity, percentage, and median fluorescence intensity.\u0000Results: CD9, CD123, and TdT were used to predict TCF3PBX1 with 80.0% sensitivity (SN) and 100% specificity (SP). CD20 and CD66 were used to predict hypoploidy with 63.0% SN and 100% SP. As a result, no useful discriminative SS was developed.\u0000Conclusions: Four SSs were proposed for the prediction of the most common cytogenetic abnormalities of Saudi B-ALL.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43794462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joan A Loayza-Castro, Luisa Erika Milagros Vásquez-Romero, Gianella Zulema Zeñas-Trujillo, Victor Juan Vera-Ponce, Jenny Raquel Torres-Malca, Norka Rocío Guillén-Ponce, Jamee Guerra Valencia, Willy Ramos, Jhony A De La Cruz-Vargas
Introduction: Obstructive sleep apnea (OSA) is related to chronic kidney disease (CKD), but its association is not fully understood. Objective: To realize a systematic review with meta-analysis to determine the association between OSA and CKD. Methods: Systematic review with meta-analysis of observational studies. The search was carried out in Embase, PubMed/Medline, Scopus, and Web of Science. The data were calculated by the hazard ratio (HR). The heterogeneity was identified by I squared. Results: Five studies were included (n=6,710). The meta-analysis found an association between OSA and CKD (HR=2.00; confidence interval 95%=1.68-2.38). Conclusions: We found an association between OSA and CKD.
{"title":"Obstructive sleep apnea risk factor for chronic kidney disease: A systematic review and meta-analysis","authors":"Joan A Loayza-Castro, Luisa Erika Milagros Vásquez-Romero, Gianella Zulema Zeñas-Trujillo, Victor Juan Vera-Ponce, Jenny Raquel Torres-Malca, Norka Rocío Guillén-Ponce, Jamee Guerra Valencia, Willy Ramos, Jhony A De La Cruz-Vargas","doi":"10.29333/ejgm/13815","DOIUrl":"https://doi.org/10.29333/ejgm/13815","url":null,"abstract":"<b>Introduction: </b>Obstructive sleep apnea (OSA) is related to chronic kidney disease (CKD), but its association is not fully understood.<br /> <b>Objective</b>: To realize a systematic review with meta-analysis to determine the association between OSA and CKD.<br /> <b>Methods:</b> Systematic review with meta-analysis of observational studies. The search was carried out in Embase, PubMed/Medline, Scopus, and Web of Science. The data were calculated by the hazard ratio (HR). The heterogeneity was identified by I squared.<br /> <b>Results:</b> Five studies were included (n=6,710). The meta-analysis found an association between OSA and CKD (HR=2.00; confidence interval 95%=1.68-2.38).<br /> <b>Conclusions:</b> We found an association between OSA and CKD.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135111239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hari Hendarto, Femmy Nurul Akbar, Jewaqa Brako Muzakki, Regi Azistha Amri, Septian Nindita Adi Nugraha, Hadianti Adlani
Objectives: Cholelithiasis or gallstones has many risk factors, such as age, sex, obesity, dyslipidemia, and diabetes mellitus (DM). Studies in developing country shown that obesity, dyslipidemia, and DM occurred in 55.0%, 76.0%, and 17.7% of adults with cholelithiasis, respectively. The aim of this study is to know the proportion of cholelithiasis risk factors. Materials & methods: This retrospective study using descriptive cross sectional design performed in one of the largest referral hospital in Jakarta Indonesia. Demographic data, and laboratory examination were collected from medical record. Patients presented with cholelithiasis from the abdominal ultrasonography was enrolled into study. Results: 93 subjects were selected through consecutive sampling, where in 65.8% were female and 77.5% age>40 years. The majority was obese (47.3%) and the obesity grade I was most prevalent. Dyslipidemia was found in 19.3% subjects with proportion of high total cholesterol was 54.5%, high LDL 90.9%, high triglycerides 27.3%, and low HDL 18.2%. DM was found in 15.0% subjects. Random blood glucose had higher proportion, accounting 57.2% with mean 140.67± 89.69 mg/dl. Female and age>40 years had more proportion in cholelithiasis patients. Conclusions: Proportion of cholelithiasis with obesity 47.3%, dyslipidemia 19.3%, and diabetes 15.0%. However, the proportion of obesity, dyslipidemia and diabetes in this study was lower than other studies in Asia or developing countries. Patients with obesity grade I, high LDL and RBG>40 mg/dl should be aware to have cholelithiasis.
{"title":"Obesity, dyslipidemia, and diabetes mellitus as risk factors in cholelithiasis","authors":"Hari Hendarto, Femmy Nurul Akbar, Jewaqa Brako Muzakki, Regi Azistha Amri, Septian Nindita Adi Nugraha, Hadianti Adlani","doi":"10.29333/ejgm/13814","DOIUrl":"https://doi.org/10.29333/ejgm/13814","url":null,"abstract":"<b>Objectives:</b> Cholelithiasis or gallstones has many risk factors, such as age, sex, obesity, dyslipidemia, and diabetes mellitus (DM). Studies in developing country shown that obesity, dyslipidemia, and DM occurred in 55.0%, 76.0%, and 17.7% of adults with cholelithiasis, respectively. The aim of this study is to know the proportion of cholelithiasis risk factors.<br /> <b>Materials &amp; methods: </b>This retrospective study using descriptive cross sectional design performed in one of the largest referral hospital in Jakarta Indonesia. Demographic data, and laboratory examination were collected from medical record. Patients presented with cholelithiasis from the abdominal ultrasonography was enrolled into study.<br /> <b>Results:</b> 93 subjects were selected through consecutive sampling, where in 65.8% were female and 77.5% age&gt;40 years. The majority was obese (47.3%) and the obesity grade I was most prevalent. Dyslipidemia was found in 19.3% subjects with proportion of high total cholesterol was 54.5%, high LDL 90.9%, high triglycerides 27.3%, and low HDL 18.2%. DM was found in 15.0% subjects. Random blood glucose had higher proportion, accounting 57.2% with mean 140.67± 89.69 mg/dl. Female and age&gt;40 years had more proportion in cholelithiasis patients.<br /> <b>Conclusions:</b> Proportion of cholelithiasis with obesity 47.3%, dyslipidemia 19.3%, and diabetes 15.0%. However, the proportion of obesity, dyslipidemia and diabetes in this study was lower than other studies in Asia or developing countries. Patients with obesity grade I, high LDL and RBG&gt;40 mg/dl should be aware to have cholelithiasis.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135111242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rajkumar Krishnan Vasanthi, Benny Chaw Jie Li, V. Purushothaman, K. A, Sivakumar Chinnusamy, Rajesh Kannan Karuppaiyan, A. Subbarayalu
Background: Virtual reality (VR) is a cutting-edge technology that consists of a sophisticated user-computer interface that allows for real-time visualization and interaction by using both visual and auditory sensorial channel. The implementation of inclusive innovation using VR in health services should be considered and hence, this study is conducted to investigate the perceived usefulness and ease of using VR during physiotherapy among Malaysian physiotherapists. Materials and methods: A cross-sectional a survey through social media, with an adapted questionnaire about the perceived usefulness and simplicity of adopting VR during physiotherapy is distributed to physiotherapists in Malaysia. In total, 102 physiotherapists participated in this study. Frequency and percentage are used to analyze the data of questionnaire items. Results: Overall 62% agree that using VR would enable to accomplish tasks more quickly, 63% finds it improve job performance, 57% believes that VR would increase my productivity. 59% enhance the effectiveness on the job. 64% easier to do my job, 61% VR useful in job. Regarding perceived ease of use 57% accepts learning to operate VR would be easy for me, 55% find it easy to get VR to do what physiotherapist want it to do, 53% agrees that interaction with VR would be clear and understandable, 54% agree that it is flexible to interact with, 54% agree to be become skillful using VR and lastly 55% agree it is easy to use. Conclusions: The majority of Malaysian physiotherapists find VR slightly useful for inclusive innovation in physiotherapy, improving work efficiency and performance. However, some remain neutral regarding its overall usefulness. They also find VR neither easy nor difficult to use in terms of inclusivity.
{"title":"Perceived usefulness and ease of using virtual reality during physiotherapy–A cross-sectional survey from physiotherapists perspective","authors":"Rajkumar Krishnan Vasanthi, Benny Chaw Jie Li, V. Purushothaman, K. A, Sivakumar Chinnusamy, Rajesh Kannan Karuppaiyan, A. Subbarayalu","doi":"10.29333/ejgm/13519","DOIUrl":"https://doi.org/10.29333/ejgm/13519","url":null,"abstract":"Background: Virtual reality (VR) is a cutting-edge technology that consists of a sophisticated user-computer interface that allows for real-time visualization and interaction by using both visual and auditory sensorial channel. The implementation of inclusive innovation using VR in health services should be considered and hence, this study is conducted to investigate the perceived usefulness and ease of using VR during physiotherapy among Malaysian physiotherapists.\u0000Materials and methods: A cross-sectional a survey through social media, with an adapted questionnaire about the perceived usefulness and simplicity of adopting VR during physiotherapy is distributed to physiotherapists in Malaysia. In total, 102 physiotherapists participated in this study. Frequency and percentage are used to analyze the data of questionnaire items. \u0000Results: Overall 62% agree that using VR would enable to accomplish tasks more quickly, 63% finds it improve job performance, 57% believes that VR would increase my productivity. 59% enhance the effectiveness on the job. 64% easier to do my job, 61% VR useful in job. Regarding perceived ease of use 57% accepts learning to operate VR would be easy for me, 55% find it easy to get VR to do what physiotherapist want it to do, 53% agrees that interaction with VR would be clear and understandable, 54% agree that it is flexible to interact with, 54% agree to be become skillful using VR and lastly 55% agree it is easy to use.\u0000Conclusions: The majority of Malaysian physiotherapists find VR slightly useful for inclusive innovation in physiotherapy, improving work efficiency and performance. However, some remain neutral regarding its overall usefulness. They also find VR neither easy nor difficult to use in terms of inclusivity.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48727142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: COVID-19 spreads quickly, especially in densely populated countries like Indonesia. Understanding transmission factors can support in reducing transmission rates. The purpose of this study is to analyze the various factors that may contribute to the transmission of COVID-19 in Indonesia, especially in the first wave of pandemic. Methods: This was a cross sectional study design. The sample was selected from the new all record data or the database for recording COVID-19 cases at the health office at the research location by online system. The research was conducted in seven districts and cities across three provinces to obtain an overview of transmission in each regional characteristic. The number of samples was as high as 2,010, with confirmed cases and close contacts in Banda Aceh City, Aceh Besar District, Semarang City, Magelang District, Ternate City, South Halmahera District, and Tidore Islands City. Data analysis was done descriptively and were analyzed using Chi-square and logistic regression with SPSS software. Results: The multivariate analysis shows that five dominant factors the risk of COVID-19 transmission, there are, age, employment status, activities outside the home, medical history, and vaccination status. Age group of 20-39 years (odds ratio [OR]=1.6-1.7; 95% confidence interval [CI] 1.07-2.71), working of employment status (OR=1.51; 95% CI 1.10-2.07), have a comorbid in medical history (OR=2.39; 95% CI 1.67-3.4), have activities outside home (OR=1.82, 95% CI 1.39-2.39), and have not been vaccinated of COVID-19 (OR=3.03; 95% CI 3.37-3.87) were significantly related with an increased risk of COVID-19 transmission. Conclusions: productive age, work and activities outside the home, having comorbidities, and not having received COVID-19 vaccination are all risk factors for COVID-19 exposure. Eliminating all of these factors at the same time will undoubtedly be difficult. As a result, cross-sectoral collaboration is needed to control the spread of COVID-19 at the community and individual levels, as well as to support policy interventions to accelerate the elimination of COVID-19 cases.
导言:COVID-19传播迅速，特别是在印度尼西亚等人口稠密的国家。了解传播因素有助于降低传播速率。本研究的目的是分析可能导致COVID-19在印度尼西亚传播的各种因素，特别是在第一波大流行中。方法:采用横断面研究设计。通过在线系统从新的所有记录数据或研究点卫生办公室新冠肺炎病例记录数据库中选择样本。该研究在3个省的7个区和城市进行，以获得每个区域特征的传播概况。样本数量高达2010个，在班达亚齐市、亚齐Besar区、三宝郎市、马格朗区、特尔纳特市、南哈马黑拉区和蒂多岛市出现了确诊病例和密切接触者。数据采用描述性分析，采用SPSS软件进行卡方回归和logistic回归分析。结果:多因素分析显示，COVID-19传播风险的5个主导因素有:年龄、就业状况、外出活动、病史和疫苗接种情况。20 ~ 39岁年龄组(优势比[OR]=1.6 ~ 1.7;95%置信区间[CI] 1.07-2.71)、工作状态(OR=1.51;95% CI 1.10-2.07)，病史中有合并症(OR=2.39;95% CI 1.67-3.4)，有家庭外活动(OR=1.82, 95% CI 1.39-2.39)，未接种COVID-19疫苗(OR=3.03;95% CI 3.37-3.87)与COVID-19传播风险增加显著相关。结论:生产年龄、家庭以外的工作和活动、有合并症以及未接种COVID-19疫苗都是COVID-19暴露的危险因素。同时消除所有这些因素无疑是困难的。因此，需要跨部门合作，在社区和个人层面控制COVID-19的传播，并支持政策干预措施，以加速消除COVID-19病例。
{"title":"Determinants of risk factors for COVID-19 transmission in densely populated areas: Insights from the first wave of the pandemic","authors":"Iin Nurlinawati, Mimi Sumiarsih, Pramita Andarwati, Lely Andayasari, Ferry Efendi, Angeline Bushy","doi":"10.29333/ejgm/13520","DOIUrl":"https://doi.org/10.29333/ejgm/13520","url":null,"abstract":"Introduction: COVID-19 spreads quickly, especially in densely populated countries like Indonesia. Understanding transmission factors can support in reducing transmission rates. The purpose of this study is to analyze the various factors that may contribute to the transmission of COVID-19 in Indonesia, especially in the first wave of pandemic.\u0000Methods: This was a cross sectional study design. The sample was selected from the new all record data or the database for recording COVID-19 cases at the health office at the research location by online system. The research was conducted in seven districts and cities across three provinces to obtain an overview of transmission in each regional characteristic. The number of samples was as high as 2,010, with confirmed cases and close contacts in Banda Aceh City, Aceh Besar District, Semarang City, Magelang District, Ternate City, South Halmahera District, and Tidore Islands City. Data analysis was done descriptively and were analyzed using Chi-square and logistic regression with SPSS software.\u0000Results: The multivariate analysis shows that five dominant factors the risk of COVID-19 transmission, there are, age, employment status, activities outside the home, medical history, and vaccination status. Age group of 20-39 years (odds ratio [OR]=1.6-1.7; 95% confidence interval [CI] 1.07-2.71), working of employment status (OR=1.51; 95% CI 1.10-2.07), have a comorbid in medical history (OR=2.39; 95% CI 1.67-3.4), have activities outside home (OR=1.82, 95% CI 1.39-2.39), and have not been vaccinated of COVID-19 (OR=3.03; 95% CI 3.37-3.87) were significantly related with an increased risk of COVID-19 transmission.\u0000Conclusions: productive age, work and activities outside the home, having comorbidities, and not having received COVID-19 vaccination are all risk factors for COVID-19 exposure. Eliminating all of these factors at the same time will undoubtedly be difficult. As a result, cross-sectoral collaboration is needed to control the spread of COVID-19 at the community and individual levels, as well as to support policy interventions to accelerate the elimination of COVID-19 cases.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42860353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Husam Abazid, I. Basheti, R. A. Abu Farha, E. E. Al-Jomaa, M. Barakat, Walaa Al Safadi, Mumen F A Amer
Objective: This study aimed to shed the light on the relation between the COVID-19 outbreak and mental health, including depression and anxiety in the Middle East. Methods: This is a survey-based study that was conducted online to evaluate the impact of the COVID-19 pandemic on mental health in the Middle East countries. The survey was uploaded on Google Form platform and was distributed through Facebook and WhatsApp platform. Results: In this study, 1,281 respondents completed the online survey. Results showed higher percentages of anxiety were diagnosed post-pandemic (38.0%) compared to pre-pandemic (6.8%). Similarly, higher percentages of participants were diagnosed with depression post-pandemic (32.0%) compared with pre-pandemic (5.0%). Also, 43.4% of the participants showed that they always or most of the time felt ‘loss of desire or interest in things. Moreover, many participants (22.4%) always/most of the time felt cramps in their chest and heart as soon as they thought of the pandemic. Finally, logistic regression analysis emphasized that gender and age significantly affected the diagnosis of anxiety and depression following the pandemic (p≤0.005). Conclusions: This current study highlighted an increase in the diagnosis of anxiety and depression among Middle Eastern following the COVID-19 pandemic. These findings revealed the importance of utilizing health coping or resilience strategies, mental health awareness campaigns, and education programs by the policymakers and stakeholders.
{"title":"Impact of COVID-19 on mental health in the Middle East: A cross-sectional study","authors":"Husam Abazid, I. Basheti, R. A. Abu Farha, E. E. Al-Jomaa, M. Barakat, Walaa Al Safadi, Mumen F A Amer","doi":"10.29333/ejgm/13518","DOIUrl":"https://doi.org/10.29333/ejgm/13518","url":null,"abstract":"Objective: This study aimed to shed the light on the relation between the COVID-19 outbreak and mental health, including depression and anxiety in the Middle East.\u0000Methods: This is a survey-based study that was conducted online to evaluate the impact of the COVID-19 pandemic on mental health in the Middle East countries. The survey was uploaded on Google Form platform and was distributed through Facebook and WhatsApp platform.\u0000Results: In this study, 1,281 respondents completed the online survey. Results showed higher percentages of anxiety were diagnosed post-pandemic (38.0%) compared to pre-pandemic (6.8%). Similarly, higher percentages of participants were diagnosed with depression post-pandemic (32.0%) compared with pre-pandemic (5.0%). Also, 43.4% of the participants showed that they always or most of the time felt ‘loss of desire or interest in things. Moreover, many participants (22.4%) always/most of the time felt cramps in their chest and heart as soon as they thought of the pandemic. Finally, logistic regression analysis emphasized that gender and age significantly affected the diagnosis of anxiety and depression following the pandemic (p≤0.005).\u0000Conclusions: This current study highlighted an increase in the diagnosis of anxiety and depression among Middle Eastern following the COVID-19 pandemic. These findings revealed the importance of utilizing health coping or resilience strategies, mental health awareness campaigns, and education programs by the policymakers and stakeholders.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48309421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Musical hallucinations (MHs) is a heterogeneous phenomenon. Multiple case reports and series have improved our understanding of this complex phenomenon. This systematic review aims to assess the available evidence regarding MHs. Methods: PubMed and ProQuest databases were searched for articles published between 2005 and 2022. The keywords used for the search were “music,” “musical,” “hallucinations,” and “hallucinosis.” Results: The search identified 421 articles; however, only 67 were selected. A total of 77 patients were selected from case reports and series. We identified 50 articles with single cases, four articles with two cases, four articles with three cases, and one article with six cases. Eight additional articles that provided information regarding the prevalence of MHs were included in the review. Conclusions: MHs are common among older individuals, women, and hearing-impaired individuals. The etiologies include psychiatric, neurological, hearing impairments, and substances. Content of MHs is typically familiar songs/music. No randomized controlled studies are available for determining the treatment for MHs.
{"title":"The phenomenon of musical hallucinations: An updated review","authors":"Feras A Al-Awad","doi":"10.29333/ejgm/13522","DOIUrl":"https://doi.org/10.29333/ejgm/13522","url":null,"abstract":"Introduction: Musical hallucinations (MHs) is a heterogeneous phenomenon. Multiple case reports and series have improved our understanding of this complex phenomenon. This systematic review aims to assess the available evidence regarding MHs.\u0000Methods: PubMed and ProQuest databases were searched for articles published between 2005 and 2022. The keywords used for the search were “music,” “musical,” “hallucinations,” and “hallucinosis.”\u0000Results: The search identified 421 articles; however, only 67 were selected. A total of 77 patients were selected from case reports and series. We identified 50 articles with single cases, four articles with two cases, four articles with three cases, and one article with six cases. Eight additional articles that provided information regarding the prevalence of MHs were included in the review.\u0000Conclusions: MHs are common among older individuals, women, and hearing-impaired individuals. The etiologies include psychiatric, neurological, hearing impairments, and substances. Content of MHs is typically familiar songs/music. No randomized controlled studies are available for determining the treatment for MHs.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44985165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The epidemiology of type 1 diabetes mellitus (T1DM) in children aged 0-17 in Kazakhstan was explored using aggregated large-scale healthcare data from the unified national electronic health system (UNEHS) in 2014-2021. Incidence, period prevalence, and mortality rates per 100,000 population at risk were calculated. Cox proportional hazards regression modelling and Kaplan-Meier methodology were used. The follow-up period was from the initial date of T1DM until death or the end of the follow-up (31 December 2021). Among the 11,088 patients, the incidence rate of T1DM decreased from 28.1 to 24.5 per 100,000 population, whereas the period prevalence rate increased from 48.8 to 179.1, and the mortality rate rose from 0.18 to 0.67. Diagnosis at age 0-1 years (hazards ratio [HR] 4.42), presence of nephropathy (HR 8.94) or neoplasms (HR 1.64) were associated with a higher risk of death, while the presence of retinopathy (HR 0.31) was associated with a lower risk of death.
{"title":"Epidemiology of type 1 diabetes mellitus in children in Kazakhstan: Data from unified national electronic health system 2014-2021","authors":"Dinara Galiyeva, Dmitriy Syssoyev, Kamilla Mussina, Arnur Gusmanov, Temirgali Aimyshev, Kuralay Atageldiyeva, Marzhan Rakhimzhanova, Abduzhappar Gaipov, Dimitri Poddighe","doi":"10.29333/ejgm/13663","DOIUrl":"https://doi.org/10.29333/ejgm/13663","url":null,"abstract":"The epidemiology of type 1 diabetes mellitus (T1DM) in children aged 0-17 in Kazakhstan was explored using aggregated large-scale healthcare data from the unified national electronic health system (UNEHS) in 2014-2021. Incidence, period prevalence, and mortality rates per 100,000 population at risk were calculated. Cox proportional hazards regression modelling and Kaplan-Meier methodology were used. The follow-up period was from the initial date of T1DM until death or the end of the follow-up (31 December 2021). Among the 11,088 patients, the incidence rate of T1DM decreased from 28.1 to 24.5 per 100,000 population, whereas the period prevalence rate increased from 48.8 to 179.1, and the mortality rate rose from 0.18 to 0.67. Diagnosis at age 0-1 years (hazards ratio [HR] 4.42), presence of nephropathy (HR 8.94) or neoplasms (HR 1.64) were associated with a higher risk of death, while the presence of retinopathy (HR 0.31) was associated with a lower risk of death.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134957498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this letter, some peculiarities, challenges, and possible limitations of using ChatGPT in the field of medicine are discussed.
在这封信中，讨论了在医学领域使用ChatGPT的一些特点、挑战和可能的限制。
{"title":"Some challenges and limitations of using ChatGPT in medicine","authors":"M. Tovani-Palone","doi":"10.29333/ejgm/13263","DOIUrl":"https://doi.org/10.29333/ejgm/13263","url":null,"abstract":"In this letter, some peculiarities, challenges, and possible limitations of using ChatGPT in the field of medicine are discussed.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69938068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Osman Koksal, A. Duyan Çamurdan, Sebnem Soysal Acar, Nur Baran Aksakal, Bahar Çuhacı Çakır
Introduction: The aim of this study is to determine whether the anxiety levels of mothers before and after complementary feeding (CF) initiation negatively affect the transition period of infants to CF. Materials and methods: The study was conducted with 150 mothers and their infants of five months of age who had not yet started CF. Beck’s depression inventory, state-trait anxiety inventory, and a questionnaire were administered to mothers. The level of statistical significance was accepted as p<0.05 in this study. Results: In this study, no statistically significant relationship was found between the transition period to CF and maternal anxiety levels (p>0.05). The relationship between eating snacks and inadequate weight gain was found significant (p=0.020). Conclusions: In our study, the anxiety levels of the mothers did not increase in the CF period. Although there was no statistically significant, the presence of anxiety in mothers requires a unique approach and support for mothers and their infants.
{"title":"The effect of maternal anxiety levels on the transition period to complementary feeding","authors":"Ali Osman Koksal, A. Duyan Çamurdan, Sebnem Soysal Acar, Nur Baran Aksakal, Bahar Çuhacı Çakır","doi":"10.29333/ejgm/13455","DOIUrl":"https://doi.org/10.29333/ejgm/13455","url":null,"abstract":"Introduction: The aim of this study is to determine whether the anxiety levels of mothers before and after complementary feeding (CF) initiation negatively affect the transition period of infants to CF.\u0000Materials and methods: The study was conducted with 150 mothers and their infants of five months of age who had not yet started CF. Beck’s depression inventory, state-trait anxiety inventory, and a questionnaire were administered to mothers. The level of statistical significance was accepted as p<0.05 in this study.\u0000Results: In this study, no statistically significant relationship was found between the transition period to CF and maternal anxiety levels (p>0.05). The relationship between eating snacks and inadequate weight gain was found significant (p=0.020).\u0000Conclusions: In our study, the anxiety levels of the mothers did not increase in the CF period. Although there was no statistically significant, the presence of anxiety in mothers requires a unique approach and support for mothers and their infants.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44743267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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