European Archives of Paediatric Dentistry最新文献

Aim: This study aimed to investigate the correlation between subjective pain threshold (SPT), daily pain recovery (PR) during the first postoperative week, and patient/surgical characteristics, while evaluating changes in SPT across multiple surgeries. Additionally, it assessed how perceived quality of life correlates with SPT and PR in adolescents undergoing lower third molar germectomy.

Methods: A prospective clinical study was conducted at the Paediatric Surgery Unit, Sapienza University of Rome, involving 51 patients aged 10-16 years undergoing lower third molar germectomy. SPT and daily PR were measured using the Visual Analogue Scale (VAS) during the first postoperative week, and quality of life was evaluated using the SF-12 questionnaire at 1-week follow-up.

Results: A total of 87 germectomies were performed, with 36 patients undergoing a second surgery. The mean age was 13.86 ± 1.81 years. Mean VAS scores increased from 4.2 ± 1.5 for Intervention 1 to 4.8 ± 1.6 for Intervention 2. Longer operative times were associated with higher PR scores on postoperative day 3. Higher PR scores correlated with greater limitations in daily activities and emotional well-being, while lower PR scores were linked to better self-perceived health.

Conclusion: SPT and PR are influenced by surgical duration and self-health perception. Shorter procedures and positive self-health perception contribute to faster recovery and improved postoperative quality of life in young patients.

Purpose: This systematic review aims to consolidate existing genetic and clinical data on non-syndromic dentinogenesis imperfecta (DI) to enhance understanding of its etiology.

Methods: Electronic databases were searched for genetic familial linkage studies published in English without time restrictions. Genetic familial linkage studies that reported cases of Shield's classifications: DI-II, DI-III or DD-II were included. After removing duplicates and excluding non-eligible articles, two reviewers screened relevant articles independently, followed by data extraction.

Results: The systematic search identified 3475 articles, with 135 suitable for full-text review and a final 41 that met inclusion criteria. Within this set of studies, 10 conducted a histopathologic examination of teeth from affected participants. DSPP mutations were the most frequently reported, with 59 documented mutations. Four studies identified mutations in COL1A1 and COL1A2, revealing non-syndromic DI cases, predominantly in individuals of Asian descent. Histopathological analysis of affected teeth showed variations in pulp chamber size, dentinal tubule irregularities, enamel malformations, and mineral density reductions, depending on DI phenotype.

Conclusions: This review consolidates genetic and clinical data to advance the understanding of non-syndromic DI. It highlights the role of DSPP, COL1A1 and COL1A2 and the potential involvement of other genes, emphasizing the effectiveness of whole-exome sequencing in identifying causative mutations.

Purpose: To assess the impact of the picture exchange communication system (PECS) on oral hygiene motivation and practices in healthy children aged five to seven years.

Methods: A total of 160 healthy children aged five to seven years were included in this study. At the first visit, the participants' guardians were asked to answer a questionnaire focussing on the sociodemographic, and the oral hygiene habits of the participants. All participants received a clinical examination to assess their dental caries experience using the ICDAS score, gingival condition using the gingival index (GI), and the amount of accumulated dental plaque using the Turesky Modification of the Quigley-Hein Plaque Index (TQHI), followed by comprehensive explanation of the proper oral hygiene protocol. The participants were randomly divided into two equal groups; the PECS group and the control group. The participants were re-assessed after 6 months. The collected data were statistically analysed using the Statistical Package for Social Sciences (SPSS) software version 23 at a p-value ≤ 0.05.

Results: By the end of the follow-up period, the PECS group reported significantly greater adherence to regular tooth brushing (p = 0.006) with a frequency higher than twice per day (p < 0.000) and no need for parental motivation (p < 0.001), and had significantly lower mean GI and TQHI scores (p < 0.000). Most of the participants' guardians reported that the PECS cards were useful for use and that they would continue to use them 66/76 (86%).

Conclusion: The PECS was found to be effective in motivating children to adhere to proper tooth-brushing practices, as reflected by improvements in their oral health status and gingival condition.

Purpose: Equimolar oxygen-nitrous oxide mixture (EMONO) is considered as a reference for dental care in children. Completion of dental treatment has usually been used as a criterion to assess EMONO treatment. However, other patient-reported outcomes are needed. We sought to assess the prevalence of complete therapeutic effects (analgesia and anxiolysis) experienced by children during dental care under EMONO and identifying associated factors.

Methods: A national prospective observational multicentric study was conducted between September 2018 and June 2020 in 13 French university hospitals. Participants were children between 3 and 15 years of age requiring dental care under EMONO.

Results: 677 children were analyzed. Anxiolysis and analgesia were experienced by a large majority of patients (86.5% and 79.0%, respectively, and 73% experienced both effects). Several factors were associated with both analgesia and anxiolysis effects: the presence of expected effects (no loss of judgment and slight decrease in level of consciousness), the absence of agitation and distress, a positive perception of EMONO and ethnicity.

Conclusion: Most patients benefit from the therapeutic effects (anxiolysis and analgesia) expected by EMONO during dental treatment. It is reassuring to observe that most sociodemographic characteristics and medical history do not seem to influence the effectiveness of care. The study was registered at www.

Clinicaltrials: gov under the reference number NCT03453411.

Purpose: To evaluate and compare the effect of two enzymatic chemo-mechanical caries removal agents with conventional caries removal using rotatory instruments on the adhesion of composite resin to dentin of permanent teeth.

Methods: The sample comprised 30 permanent molars with caries lesions extending to the dentin, randomly distributed into three groups (n = 10 each): 1-Caries removal with rotary instruments (control group); 2-Caries removal with Papacárie Duo^® (F&A Laboratório Farmacêutico, São Paulo, Brazil); 3-Caries removal with Brix 3000™ (Brix S.R.L., Carcarañá, Argentina). After caries removal, the specimens were rinsed and dried. Scotchbond Universal™ adhesive (3 M, Saint Paul, Minnesota, USA) was actively applied in self-etch mode and light-cured. Resin composite increments were applied using a silicone mold (3 × 3 × 2 mm) and light-cured. Shear bond strength (MPa), work-to-debonding (J/m²), and shear modulus (kPa) were evaluated. For statistical analysis, the level of significance was set at 5%.

Results: The control group presented significantly higher shear bond strength values (8.50 ± 2.69 MPa) compared to the Brix 3000™ group (5.72 ± 1.55 MPa, p = 0.008). There were no significant differences between Papacárie Duo^® (6.66 ± 0.86 MPa) and the other groups (p > 0.05). Regarding work-to-debonding, the Papacárie Duo^® group had a significantly higher result (2944.41 ± 450.21 J/m²) than the Brix 3000™ group (1189.41 ± 504.13 J/m², p < 0.001) and the control group (967.10 ± 270.01 J/m², p < 0.001). Concerning shear modulus, the control group showed a significantly higher result (558.67 ± 168.96 kPa) than the Brix 3000™ group (339.79 ± 143.78 kPa, p = 0.008) and the Papacárie Duo^® group (223.04 ± 127.30 kPa, p < 0.001).

Conclusion: While the application of Papacárie Duo^® did not negatively affect composite resin adhesion to dentin of permanent teeth, the application of Brix 3000™ reduced adhesive forces, potentially limiting its clinical use. Further investigations are warranted to elucidate the effects of these materials on dentin substrate, particularly through clinical studies.

Purpose: The present systematic review aims to summarize the current evidence regarding various treatment modalities and their results when dealing with hypersensitivity in teeth with Molar-Incisor Hypomineralization (MIH).

Methods: Systematic searches were conducted in PubMed and Scopus using the search terms "MIH AND Hypersensitivity AND treatment." Studies involving children aged 6-18 years diagnosed with MIH and exhibiting hypersensitivity were considered for inclusion. The outcomes examined included clinical, behavioral, and psychosocial treatment options for reducing hypersensitivity. A meta-analysis was performed for six of the included articles, and the I² value was calculated to determine heterogeneity.

Results: A total of eight articles met the inclusion criteria for this review, with six eligible for the meta-analysis. Various treatment modalities, such as dental mousse, sealing, laser therapy, and crown therapy, demonstrated significant reductions in hypersensitivity individually (p < 0.05).

Conclusion: The treatment methods that offer the most effective reduction in hypersensitivity are sealing with resin composite or glass ionomer cement for mild cases of MIH, while crown therapy is more effective for severe cases of MIH. However, the small number of participants and short follow-up times limit the strength of these conclusions.

Purpose: Assess the knowledge and attitudes of parents/guardians regarding their children's oral health and their preferences regarding the treatment of carious primary teeth.

Methods: A cross-sectional study including the completion of a questionnaire by parents/guardians of healthy children aged 2-12 years attending the Department of Pediatric Dentistry (NKUA). Data were collected through 35 questions regarding demographic characteristics of the participants, oral hygiene and dietary habits, and parents' knowledge of the importance of oral health and primary teeth. Treatment preferences were assessed through clinical scenarios accompanied by colored clinical photographs. Results were presented in frequency tables and comparisons with specific child and parent-characteristics were evaluated using chi-squared and Fisher's exact test.

Results: Parents were mainly females (73%), married (81%), aged > 40 years (56%), and high school graduates (57%). Most children brushed alone (56%), twice (48%) daily, with a manual toothbrush (65%) and consumed sugary snacks daily (38%). More than two-thirds of parents recognized the relationship between oral hygiene and general health (82%) and the importance of primary teeth (72%). Almost all parents would like to restore their children's asymptomatic (94%) and symptomatic (98%) primary teeth, with pulp therapy and stainless-steel crowns being the treatment of choice (58%). The decision on treatment about cavitated/non-cavitated primary teeth was not correlated with any of the parental or child-related factors. Acceptance of minimally invasive treatments was higher among highly educated parents and parents of boys.

Conclusion: Insight into parents' perceptions and preferences regarding the treatment of primary teeth is necessary and should be considered during treatment planning.

Purpose: The purpose of this study is to evaluate the influence of photobiomodulation therapy on the regenerative potential of non-vital mature permanent teeth of healthy Canine dogs.

Methods: 54 mature roots, obtained from 27 premolars, in dogs, were selected and divided into three equal groups where Group I received regenerative endodontic procedures (REPs) using blood clot as a scaffold (positive control), Group II received similar treatment as Group I, followed by photobiomodulation therapy (study group) and Group III did not receive any intervention (negative control). Each group was further divided into three equal subgroups for the evaluation of the vascular area percentage and fibroblast count at 3 different intervals; 3, 10, and 15 weeks. Statistical analysis was performed with R statistical analysis software version 4.1.3 RESULTS: Data analysis for vascular area percentages, revealed an insignificant increase in mean values at 3 and 10 weeks for both the positive control and study group, and all values were significantly lower than the negative control (p < 0.001). At 15 weeks, there was an insignificant difference between the study group and the negative control group, with mean values was 9.76 ± 2.25, and 11.97 ± 2.37, respectively. However, both values were significantly higher than the positive control group (2.47 ± 1.0), (p < 0.001). Regarding fibroblast count, there was a gradual increase in mean values recorded at different intervals, reaching its maximum at the 15th week period; they were 41.40 ± 1.14, 56.60 ± 6.11 and 44.67 ± 17.04 for positive control, study group, and negative control respectively, with insignificant differences between the study group and negative control.

Conclusion: The results of this study support the revascularization of non-vital mature permanent teeth as an alternative treatment modality. Photobiomodulation could improve the construction of regenerated blood vessels and fibroblasts. However, further studies with longer flow-up periods and different animal models are recommended.