European Archives of Paediatric Dentistry最新文献

Purpose: The purpose of this study is to evaluate the influence of photobiomodulation therapy on the regenerative potential of non-vital mature permanent teeth of healthy Canine dogs.

Methods: 54 mature roots, obtained from 27 premolars, in dogs, were selected and divided into three equal groups where Group I received regenerative endodontic procedures (REPs) using blood clot as a scaffold (positive control), Group II received similar treatment as Group I, followed by photobiomodulation therapy (study group) and Group III did not receive any intervention (negative control). Each group was further divided into three equal subgroups for the evaluation of the vascular area percentage and fibroblast count at 3 different intervals; 3, 10, and 15 weeks. Statistical analysis was performed with R statistical analysis software version 4.1.3 RESULTS: Data analysis for vascular area percentages, revealed an insignificant increase in mean values at 3 and 10 weeks for both the positive control and study group, and all values were significantly lower than the negative control (p < 0.001). At 15 weeks, there was an insignificant difference between the study group and the negative control group, with mean values was 9.76 ± 2.25, and 11.97 ± 2.37, respectively. However, both values were significantly higher than the positive control group (2.47 ± 1.0), (p < 0.001). Regarding fibroblast count, there was a gradual increase in mean values recorded at different intervals, reaching its maximum at the 15th week period; they were 41.40 ± 1.14, 56.60 ± 6.11 and 44.67 ± 17.04 for positive control, study group, and negative control respectively, with insignificant differences between the study group and negative control.

Conclusion: The results of this study support the revascularization of non-vital mature permanent teeth as an alternative treatment modality. Photobiomodulation could improve the construction of regenerated blood vessels and fibroblasts. However, further studies with longer flow-up periods and different animal models are recommended.

Objective: The aim of this study was to assess symmetry of developmental stage of permanent teeth between the left and right side of the jaw, as well as between the maxilla and the mandible.

Methods: A sample of 150 panoramic radiographs of individuals aged 6-20 years (69 males, 81 females) were selected from an open-access radiographic collection (Maxwell Museum of Anthropology's orthodontic collection, Albuquerque, USA). All developing immature permanent teeth (n = 489) were scored by the first author using Moorrees and Demirjian tooth stages. Symmetry of developing teeth was assessed between the left and right sides of the jaw, as well as between the maxilla and the mandible using McNemar test with p < 0.05 considered significant.

Results: No significant differences were found comparing left and right sides within the maxilla (n = 489), (McNemar, p = 0.759 M, p = 0.736 D), or within the mandible (McNemar, p = 0.262 M, p = 0.707 D) using either tooth scoring method. Percentage agreement for individual teeth between left and right sides was least for third molars. Significant differences were observed comparing maxillary and mandibular teeth for both tooth scoring methods (n = 978), (McNemar, p = 0.00 M, p < 0.001 D). Percentage agreement for individual teeth between the maxilla and mandible was least for incisors.

Conclusion: In the present sample, differences in tooth formation were not significantly different in left and right side of the jaw while a significant difference (p = 0.00 M, p < 0.001 D) was observed between maxilla and mandible.

Purpose: To review the current evidence on the association between salivary protein profile and dental caries in children during mixed dentition stage.

Methods: This systematic review followed the PRISMA 2020 guidelines. Searches were run in PubMed, Scopus and Embase along with gray literature. The searches were limited to studies on humans, published from inception to February 2024. Observational studies exploring correlations between salivary proteins and caries in children during mixed dentition (6-13 years) were included. The methodological quality of included studies was analyzed independently by two reviewers using the Joanna Briggs checklist and Newcastle-Ottawa scale, respectively followed by a qualitative synthesis.

Results: A total of 17 primary studies were included. The studies recruited 1,330 subjects including 612 caries-active and 505 caries-free subjects. The total protein content was higher in caries-active subjects. Among the glycoproteins, IgA and MUC5B were higher in caries-free subjects while the levels of MUC7 were lower in the caries-free group. Antimicrobial peptides and proteinase-3 levels were also higher in caries-free subjects. Contradictory findings were reported for the association of α- amylase and carbonic anhydrase with caries status. The included studies were categorized as good quality (n = 4), fair quality (n = 12) and poor quality (n = 1).

Conclusion: Based on fair-quality studies included in this review and within its limitations, the findings revealed that salivary proteins may be associated with susceptibility to dental caries in mixed dentition. Total salivary proteins are upregulated in caries-active subjects while salivary IgA, antimicrobial peptides and proteinase-3 are increased in caries-free subjects.

Systematic review registration: The study protocol was registered in PROSPERO (registration number CRD42024517374).

Purpose: The use of cone-beam computed tomographies (CBCT) in orthodontics and pediatric dentistry is constantly increasing. The aim of this systematic review was to critically appraise and summarize evidence from clinical studies on the prevalence of incidental findings from CBCTs of children and adolescents.

Methods: Systematic literature searches without restrictions were undertaken in eight databases from inception up to March 2024 for studies reporting on incidental findings from CBCT images of children and adolescents. After duplicate study selection, data extraction, and risk of bias assessment with a custom tool based on the Joanna Briggs institute's tool for prevalence studies, qualitative (narrative) data synthesis was performed.

Results: Ten studies covering a total of 1818 patients (48.5% male; average age 12.3 years) were included. The prevalence of incidental findings ranged from 0.4 to 80.3%, but high heterogeneity was seen between studies (I² = 99%). Incidental findings were most often related to airways (63.7%), followed by bone (23.6%), teeth (19.2), spine (26.2) and temporomandibular joint (3.8%). However, several methodological issues existed with included studies (incomplete reporting of patient- or CBCT-related details, incomplete categorization and reporting on the severity of findings, small sample sizes, and research transparency issues).

Conclusion: Evidence indicates that incidental findings can be often found in the CBCTs of child and adolescent patients. However, when a CBCT image is justified for children or adolescents, it should be adequately assessed for incidental findings by either a specialist oral and maxillofacial radiologist or a dentist with appropriate training and experience.

Aim: This prospective clinical study aimed to clinically investigate the efficiency of (GIC) glass-ionomer cement application (Ionostar Plus + Easy Glaze, VOCO) in reducing hypersensitivity in permanent molars affected by molar incisor hypomineralisation when assessed immediately (15 min) and 12 weeks after its application.

Materials and methods: Children with at least one hypersensitive MIH-affected permanent molar (MIH-TNI-3 or 4). The pre-treatment status was evaluated and only included if they did not receive a tooth-specific in-office desensitizing treatment within one month. Clinical pain assessments were performed using the schiff score air sensitivity scale (SCASS) and Wong-baker faces Scale (WBFS).

Results: This study involved 25 participants (mean age 8.6 ± 1.85 years) with 43 hypersensitive MIH-molars of which about half were SCASS 3 (n = 24, 55.8%) and SCASS 2 (n = 19, 44.2%). Regarding hypersensitivity, the reported mean SCASS score reduced significantly from 2.56 (± 0.50) at baseline to 1.14 (± 0.96) after 15 min of GIC sealant application and even further to 0.71 (± 0.89) after 12 weeks (P < 0.001, Paired t test). Similarly, reported WBFS scores also significantly reduced from 5.81 (± 2.50; Range = 2-10) at baseline to 2.88 (± 2.31; Range = 0-10) after 15 min and to 2.95 (± 2.17) after 12 weeks, respectively (P < 0.001, Paired t test). The mean reduction in SCASS scores was 1.3 (± 0.6) and 1.4 (± 1.0) for baseline SCASS 2 vs. 3, respectively.

Conclusion: GIC coverage is effective in providing clear instant relief from hypersensitivity in MIH molars in schoolchildren, which improves even further over a period of 12 weeks.

Purpose: People with sensory impairments (SI) face unique challenges in out-of-home care, especially in oral health (OH) care, compared to the general population. Various assistive technologies (ATs) and media are used to influence OH behaviors and outcomes for individuals with SI. This systematic review (SR) aimed to identify the types of ATs and assess their effectiveness for individuals with SI.

Methods: A comprehensive search strategy was applied across Scopus, PubMed, Cochrane Library, ProQuest, and Scopus databases, using expert-validated keywords, with manual searches for relevant articles published from June 2013 to June 2023. The SR followed the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. Eligible studies focused on the use of ATs as OH education tools for individuals with SI and assessed their impact on OH behavior and status.

Results: Eighteen of the 1298 identified studies were included in the data synthesis. ATs, such as images, software, multimedia, audio, video, audio-tactile performance, and combination methods, were effective for OH care in individuals with SI. However, this SR limitations include study heterogeneity in sample sizes, intervention types, and outcomes, as well as the exclusion of non-English studies.

Conclusions: Oral health education using a combination of video training and audio-tactile performance is particularly effective for individuals with SI, engaging multiple senses for learning. Future research should focus on standardizing methodologies and incorporating larger sample sizes to enhance the efficacy of these technologies in improving OH care for individuals with SI. PROSPERO REG. NO.: CRD42023485523.

Purpose: Identifying factors that disrupt cooperation during radiographic examination, such as dental fear and the gag reflex, is crucial for achieving optimal radiographic outcomes. The aim of the present study is to evaluate the levels of dental fear and cooperation amongst children aged 4-9 years undergoing intraoral radiographic examination at different stages of dental treatment. It also investigates the impact of the gag reflex on children's behaviour during intraoral radiographic examination.

Methods: A total of 89 children with no prior dental experience were randomly divided into two groups (G1, G2). Children in G1 underwent radiographic examination during their first dental visit, whilst children in G2 underwent the same after the completion of dental prophylaxis at their second visit. Variables assessed included dental fear, gagging and behaviour during radiographic examination. Multivariate logistic and linear regression analysis were performed to assess the variables that have an impact on behaviour during radiographic examination and on dental fear, respectively.

Results: Children in G2 were more likely to exhibit better behaviour during radiographic examination than G1children (OR: 4.709, p value = 0.036). In addition, G1 children demonstrated a greater increase of CFSS-DS score compared to G2 children (β = - 0.698, p value = 0.001) after the second appointment. Gagging during radiographic examination was significantly associated with lower Frankl score during the examination (p = 0.015).

Conclusion: Gradual exposure to radiographic examination may significantly enhance children's cooperation during the procedure and confine the progression of dental fear. In contrast, the presence of a gag reflex can compromise patient's cooperation during intraoral radiographic assessment.