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WHO essential medicines for dentistry: a focus on patients with special care needs. 世卫组织牙科基本药物:关注有特殊护理需求的患者。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-02 DOI: 10.1007/s40368-024-00932-4
M R Tovani-Palone
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引用次数: 0
Development of 'OXIS Classification' calibration website for dental researchers. 为牙科研究人员开发 "OXIS 分类 "校准网站。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-05-19 DOI: 10.1007/s40368-024-00908-4
Tarun Walia, Murugan Satta Muthu, Sneha Suhas Patil, Raghavendra Manjunath Shetty

Purpose: The variations in interproximal contact areas have been categorised open (O), point (X), straight (I), and curved contact (S). This is based on their shapes and termed as OXIS classification. The interactive OXIS calibration website was developed to assist researchers seeking appropriate knowledge, minimise the overload of material, optimise efficiency in calibration and, to provide repositories for clinicians, healthcare workers, and policymakers.

Methods: The website was developed in two phases. The first phase of development included expert group discussion, Focus Group Discussion (FGD), and the implementation of FGD recommendations. The second phase emphasised registration and development of the interactive web portal on OXIS classification. The developed website was subjected to user experience testing, functional testing, performance testing, security testing, device, platform testing, and then hosted. Calibrated students and faculties evaluated it with the help of Suitability Assessment of Materials (SAM) and System Usability Scale (SUS). Finally, after amendments, the website was evaluated by non-calibrated researchers and multidisciplinary experts.

Results: The total agreement was 74% for overall SAM category. Pooled mean total score of SUS was 52.7 (SD 7.17; range 45-67.5), indicating an average score.

Conclusion: The content of the developed website has been evaluated as "satisfactory" and its technical quality as "of higher standards".

目的:根尖间接触区的变化可分为开放接触区(O)、点接触区(X)、直接触区(I)和弯接触区(S)。这是根据它们的形状划分的,称为 OXIS 分类。开发互动式 OXIS 校准网站的目的是帮助研究人员寻求适当的知识,最大限度地减少过多的资料,优化校准效率,并为临床医生、医疗工作者和决策者提供资料库:该网站分两个阶段开发。第一阶段的开发包括专家组讨论、焦点小组讨论(FGD)和落实 FGD 建议。第二阶段的重点是注册和开发 OXIS 分类互动门户网站。开发的网站经过了用户体验测试、功能测试、性能测试、安全测试、设备和平台测试,然后托管。经过校准的学生和教师借助材料适用性评估(SAM)和系统可用性量表(SUS)对网站进行了评估。最后,在对网站进行修改后,由未经校准的研究人员和多学科专家对网站进行评估:结果:SAM 类别的总体一致率为 74%。SUS总分的合计平均值为52.7(标准差为7.17;范围为45-67.5),表明得分一般:结论:所开发网站的内容被评为 "令人满意",其技术质量被评为 "较高标准"。
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引用次数: 0
Association of parent-reported timing of first tooth emergence and ECC: a secondary analysis of a case-control study. 家长报告的第一颗牙齿萌出时间与幼儿保育中心的关系:一项病例对照研究的二次分析。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-06-04 DOI: 10.1007/s40368-024-00914-6
M S Muthu, A Ganesh, S Anandan, G Thiruvengadam, R Padmanabhan, S Nuvvula

Purpose: Tooth eruption is a dynamic process. Appearance of any part of the cusp through gingiva may be a clinical marker of eruption. Early childhood caries (ECC) is a public health problem globally. This study aimed to assess the relationship between parent-reported timing of first tooth emergence and ECC in toddlers.

Methods: This study is a secondary data analysis of 627 toddlers involved in a case-control study on sleep-time feeding practises in children. The children were categorised into four groups based on the parent-reported timing of first primary tooth emergence (G1-when the first primary tooth emerged before 6 months of age, G2-between 7 and 9 months; G3-10 to 12 months and G4-when the first primary tooth emerged after 12 months of age). Univariate binary logistic regression analysis was performed to evaluate the association between timing of first tooth emergence and ECC.

Results: The mean age of the children was 24.4 ± 7.3 months (cases, that is children with ECC-25.4 ± 6.9 months, controls, that is children without ECC-23.6 ± 7.5 months). Of 60 children, whose first tooth erupted before 6 months of age, 35 (12%) were cases compared to 25(8%) controls. Amongst the cases, boys had more caries than girls (p < 0.05). Of the anterior teeth, 22% of the emerged teeth were decayed in the first group, followed by 19%, 16% and 10% in the second, third and fourth groups, respectively (p < 0.05). Analysis of the posterior teeth showed a lower percentage of decayed teeth with delayed emergence of the first primary tooth (p < 0.05). Children whose teeth emerged before 6 months of age had an odds ratio of 3.5 (95% CI 1.49, 8.42) (p = 0.004).

Conclusion: This study concluded that the early emergence of the first primary tooth, as reported by the parent, was associated with an increased risk of developing ECC.

目的:牙齿萌出是一个动态过程。通过牙龈出现尖牙的任何部分都可能是萌出的临床标志。儿童早期龋齿(ECC)是一个全球性的公共卫生问题。本研究旨在评估家长报告的幼儿第一颗牙齿萌出时间与 ECC 之间的关系:本研究对参与儿童睡眠时间喂养方式病例对照研究的 627 名幼儿进行了二次数据分析。根据家长报告的第一颗乳牙萌出的时间,这些儿童被分为四组(G1--第一颗乳牙萌出的时间在6个月之前;G2--第一颗乳牙萌出的时间在7至9个月之间;G3--第一颗乳牙萌出的时间在10至12个月之间;G4--第一颗乳牙萌出的时间在12个月之后)。研究人员进行了单变量二元逻辑回归分析,以评估第一颗乳牙萌出时间与 ECC 之间的关联:结果:儿童的平均年龄为 24.4 ± 7.3 个月(病例,即患有 ECC 的儿童-25.4 ± 6.9 个月;对照组,即未患有 ECC 的儿童-23.6 ± 7.5 个月)。在 60 名在 6 个月前萌出第一颗牙齿的儿童中,35 名(12%)为病例,对照组为 25 名(8%)。在病例中,男孩的龋齿发生率高于女孩(P本研究的结论是,家长报告的第一颗乳牙萌出时间过早与罹患 ECC 的风险增加有关。
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引用次数: 0
Proteomic profiling of human dental enamel affected by molar incisor hypomineralisation of different clinical severity grades: an in vitro study. 不同临床严重程度的磨牙切牙低矿化所影响的人类牙釉质的蛋白质组分析:一项体外研究。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-06-06 DOI: 10.1007/s40368-024-00911-9
F Rexhaj, N Sabel, A Robertson, T Lundgren

Purpose: The aim of this study was to explore the potential to profile and distinguish varying clinical severity grades of MIH, compared to normal enamel, using proteomics.

Methods: Liquid chromatography-mass spectrometry analyses were conducted on enamel samples of extracted teeth, from 11 children and adolescents, spanning an age range of 6-18 years. Enamel powder samples were collected from extracted, third molars (n = 3) and first permanent molars diagnosed with MIH (n = 8). The MIH tooth samples were categorized into subgroups based on clinical severity grade. The data were statistically analyzed using ANOVA and Welch's t test.

Results: Teeth affected by MIH exhibited a diverse array of proteins, each with different functions related to dental enamel, distinguishing them from their normal enamel counterparts. The application of microdissection combined with LC-MS techniques has revealed the potential to discern unique proteomic profiles among MIH-affected teeth, characterized by varying clinical severity grades. Both analyzed MIH groups displayed consistent trends in the presentation of biological processes, including underabundance of proteins primarily associated with cell organization and biogenesis. Furthermore, proteins linked to cell death were overabundant in both MIH groups.

Conclusion: Proteomics enabled the detection and differentiation of various proteins across different clinical severity grades of MIH.

目的:本研究的目的是利用蛋白质组学的方法,探讨与正常牙釉质相比,对不同临床严重程度的MIH进行剖析和区分的可能性:对 11 名 6-18 岁儿童和青少年的拔牙珐琅质样本进行了液相色谱-质谱分析。珐琅质粉末样本取自被诊断为MIH的拔出第三磨牙(3颗)和第一恒磨牙(8颗)。根据临床严重程度将 MIH 牙齿样本分为不同的亚组。采用方差分析和韦尔奇 t 检验对数据进行统计分析:结果:受MIH影响的牙齿表现出多种多样的蛋白质,每种蛋白质都具有与牙釉质相关的不同功能,使它们有别于正常的牙釉质。显微切割结合 LC-MS 技术的应用揭示了在受 MIH 影响的牙齿中发现独特蛋白质组图谱的潜力,这些图谱以不同的临床严重程度等级为特征。两组受分析的 MIH 患者在生物过程的表现上呈现出一致的趋势,包括主要与细胞组织和生物生成相关的蛋白质含量不足。此外,与细胞死亡有关的蛋白质在两组 MIH 中都过量存在:蛋白质组学能够检测和区分不同临床严重程度等级的 MIH 中的各种蛋白质。
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引用次数: 0
Chemotherapy-induced oral mucositis: hierarchical analysis of recurrence factors. 化疗引起的口腔黏膜炎:复发因素的层次分析。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-07-05 DOI: 10.1007/s40368-024-00919-1
T S de Macêdo, M C F de Melo, A K A Ferreira, E L M S da Silva-Selva, G P Godoy, A de F Caldas Júnior

Purpose: This study aimed to analyze, through a hierarchical model, the risk factors associated with the recurrence of chemo-induced oral mucositis (OM) in children and adolescents.

Methods: A retrospective cohort with 31 individuals of both sexes, aged 1-18 years, who were undergoing chemotherapy, and presented OM lesions was conducted. Data collection included analysis of medical records, interviews, and intraoral examination. Information regarding patients' socioeconomic and demographic profile, underlying disease, antineoplastic regimen, hematological condition, and oral health status were collected. To assess the association of independent variables with the outcome, the Chi-square, Fisher's Exact, and Mann-Whitney tests were used, in addition to a binary logistic regression model, with a maximum error of 5% and a 95% confidence interval.

Results: Significant associations were observed between the history of OM and the diagnosis of the child/adolescent, neutrophil count, previous cancer treatments and the chemotherapy scheme in use (p < 0.05). Binary logistic regression revealed a 13.69 higher risk of developing OM recurrence in individuals who received high-dose methotrexate (MTX) therapy.

Conclusion: Socioeconomic and demographic factors did not influence OM recurrence. However, clinical variables, such as neutropenia, diagnosis of leukemia, and high-dose MTX protocols increase the chance of OM new cases.

目的:本研究旨在通过层次模型分析与儿童和青少年化疗引起的口腔黏膜炎(OM)复发相关的风险因素:方法:对 31 名正在接受化疗并出现口腔黏膜炎病变的 1-18 岁男女患者进行了回顾性队列研究。数据收集包括病历分析、访谈和口腔内检查。收集的信息涉及患者的社会经济和人口概况、基础疾病、抗肿瘤疗法、血液状况和口腔健康状况。为了评估自变量与结果之间的关系,除了使用二元逻辑回归模型(最大误差为 5%,置信区间为 95%)外,还使用了卡方检验(Chi-square)、费雪精确检验(Fisher's Exact)和曼惠特尼检验(Mann-Whitney):观察发现,OM 病史与儿童/青少年的诊断、中性粒细胞计数、既往癌症治疗和正在使用的化疗方案之间存在显著关联(p 结论:OM 病史与儿童/青少年的诊断、中性粒细胞计数、既往癌症治疗和正在使用的化疗方案之间存在显著关联:社会经济和人口学因素不会影响 OM 复发。然而,中性粒细胞减少症、白血病诊断和大剂量 MTX 方案等临床变量会增加 OM 新病例的发生几率。
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引用次数: 0
qPCR assay optimisation for a clinical study comparing oral health risk in Rett syndrome. 为一项比较 Rett 综合征口腔健康风险的临床研究优化 qPCR 检测。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-06-26 DOI: 10.1007/s40368-024-00912-8
Y Y L Lai, J Downs, S Leishman, H M Leonard, L J Walsh, S Zafar

Purpose: This study aimed to validate qPCR assays for specific microbiota, for use on dental plaque samples stored on Whatman FTA cards to compare relative oral health risk in Rett syndrome.

Methods: Supragingival dental plaque samples were collected, using a sterile swab, (COPAN FLOQswab™) swabbed onto Whatman FTA™ cards. DNA extraction was performed using a modified Powersoil™ protocol. Where published assays were unsuitable, species-specific qPCR assays for caries-associated, gingivitis-associated and oral-health-associated bacteria were designed using multiple sequence alignment, Primer3Plus and PrimerQuest. Assays were run using absolute quantification. Limit of detection (LOD) and limit of quantification (LOQ) were calculated, and PCR products verified by Sanger sequencing.

Results: Most assays allowed detection using real-time qPCR with high specificity on samples collected on FTA cards. Several assays showed low or even single gene copy numbers on the test samples.

Conclusion: Assays were optimised for detection and evaluation of oral health risk in dental plaque samples stored on FTA cards when cold storage is not feasible, except for F. nucleatum. Several assays showed gene copy numbers less than the LOQ or outside the range of the standard curve, so there is merit in optimising these assays using digital droplet PCR.

目的:本研究旨在对特定微生物群的 qPCR 检测进行验证,以用于保存在 Whatman FTA 卡上的牙菌斑样本,从而比较雷特综合征患者的相对口腔健康风险:使用无菌拭子(COPAN FLOQswab™)采集龈上牙菌斑样本,并将其涂在 Whatman FTA™ 卡上。DNA 提取采用改良的 Powersoil™ 方案。如果已公布的检测方法不合适,则使用多重序列比对、Primer3Plus 和 PrimerQuest 设计龋齿相关细菌、牙龈炎相关细菌和口腔健康相关细菌的物种特异性 qPCR 检测方法。检测采用绝对定量法。计算检测限(LOD)和定量限(LOQ),并通过 Sanger 测序验证 PCR 产物:结果:大多数检测方法都能使用实时 qPCR 对采集在 FTA 卡上的样本进行检测,而且特异性很高。有几种检测方法在检测样本上显示出较低甚至单一的基因拷贝数:结论:在无法进行冷藏的情况下,对保存在 FTA 卡上的牙菌斑样本进行检测和评估口腔健康风险的检测方法进行了优化,但核酸酵母菌除外。有几种检测方法的基因拷贝数低于 LOQ 或超出了标准曲线的范围,因此使用数字液滴 PCR 对这些检测方法进行优化是有价值的。
{"title":"qPCR assay optimisation for a clinical study comparing oral health risk in Rett syndrome.","authors":"Y Y L Lai, J Downs, S Leishman, H M Leonard, L J Walsh, S Zafar","doi":"10.1007/s40368-024-00912-8","DOIUrl":"10.1007/s40368-024-00912-8","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to validate qPCR assays for specific microbiota, for use on dental plaque samples stored on Whatman FTA cards to compare relative oral health risk in Rett syndrome.</p><p><strong>Methods: </strong>Supragingival dental plaque samples were collected, using a sterile swab, (COPAN FLOQswab™) swabbed onto Whatman FTA™ cards. DNA extraction was performed using a modified Powersoil™ protocol. Where published assays were unsuitable, species-specific qPCR assays for caries-associated, gingivitis-associated and oral-health-associated bacteria were designed using multiple sequence alignment, Primer3Plus and PrimerQuest. Assays were run using absolute quantification. Limit of detection (LOD) and limit of quantification (LOQ) were calculated, and PCR products verified by Sanger sequencing.</p><p><strong>Results: </strong>Most assays allowed detection using real-time qPCR with high specificity on samples collected on FTA cards. Several assays showed low or even single gene copy numbers on the test samples.</p><p><strong>Conclusion: </strong>Assays were optimised for detection and evaluation of oral health risk in dental plaque samples stored on FTA cards when cold storage is not feasible, except for F. nucleatum. Several assays showed gene copy numbers less than the LOQ or outside the range of the standard curve, so there is merit in optimising these assays using digital droplet PCR.</p>","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11341660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141459920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The need for a comprehensive case-severity-grading tool for molar-incisor hypomineralisation (MIH). 需要一个针对臼齿嵌合体矿化不足(MIH)的综合病例严重性分级工具。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-04-26 DOI: 10.1007/s40368-024-00903-9
M Brejawi, A Venkiteswaran, S M O Ergieg, B Md Sabri
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引用次数: 0
Tensile bond strength between paediatric prefabricated zirconia crowns and primary maxillary incisors when using various types of luting cements: an in vitro study. 儿科预制氧化锆牙冠与上颌原切牙之间的拉伸粘接强度(使用各种类型的粘接剂):体外研究。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-04-12 DOI: 10.1007/s40368-024-00890-x
P Pengpue, V Sirimaharaj, P Chaijareenont, W Chinadet

Purpose: There is limited evidence regarding the most appropriate type of luting cement for paediatric prefabricated zirconia crowns (PZCs) in primary maxillary incisors. The retention of PZCs is dependent on the bond strength of luting cement between PZCs and primary maxillary incisors. The aim of this study was to evaluate the tensile bond strengths between PZCs and primary maxillary incisors with different types of luting cements.

Methods: Thirty freshly extracted human primary maxillary incisors were prepared and randomly divided into three groups corresponding to three luting cements: bioactive cement, resin cement, and resin-modified glass ionomer cement (RMGIC), and then restored with PZCs. Tensile bond strengths were evaluated by a universal testing machine. The results were analysed using one-way ANOVA with Tukey's post-hoc test (p < 0.05).

Results: The means of the tensile bond strengths were 1.43 ± 0.85 MPa, 0.91 ± 0.63 MPa, and 0.56 ± 0.39 MPa for the bioactive cement, resin cement, and RMGIC groups, respectively. A significant difference in tensile bond strength was observed between the bioactive cement and the RMGIC group (p < 0.05) but there was no significant difference in tensile bond strength between the resin cement group and the others.

Conclusion: Types of luting cement influenced the tensile bond strength between PZCs and primary maxillary incisors. The bioactive cement showed higher tensile bond strength than the resin cement and RMGIC.

目的:关于儿童上颌原切牙预制氧化锆冠(PZC)最合适的粘结剂类型,目前证据有限。PZC的固位取决于PZC和上颌原切牙之间的粘结强度。本研究的目的是评估 PZC 与上颌原切牙之间不同类型的粘结水门汀的拉伸粘结强度:制备 30 颗新鲜拔出的人类上颌原切牙,并将其随机分为三组,分别与生物活性水门汀、树脂水门汀和树脂改性玻璃离聚体水门汀(RMGIC)这三种粘结水门汀相对应,然后用 PZCs 进行修复。拉伸粘结强度由万能试验机进行评估。结果采用单因素方差分析和 Tukey 后检验(p)进行分析:生物活性水门汀组、树脂水门汀组和 RMGIC 组的拉伸粘结强度平均值分别为 1.43 ± 0.85 MPa、0.91 ± 0.63 MPa 和 0.56 ± 0.39 MPa。生物活性水门汀组和 RMGIC 组的拉伸粘结强度存在明显差异(p 结论:生物活性水门汀组和 RMGIC 组的拉伸粘结强度存在明显差异:粘结水泥的类型会影响 PZC 和上颌原切牙之间的拉伸粘结强度。生物活性粘结剂的拉伸粘结强度高于树脂粘结剂和 RMGIC。
{"title":"Tensile bond strength between paediatric prefabricated zirconia crowns and primary maxillary incisors when using various types of luting cements: an in vitro study.","authors":"P Pengpue, V Sirimaharaj, P Chaijareenont, W Chinadet","doi":"10.1007/s40368-024-00890-x","DOIUrl":"10.1007/s40368-024-00890-x","url":null,"abstract":"<p><strong>Purpose: </strong>There is limited evidence regarding the most appropriate type of luting cement for paediatric prefabricated zirconia crowns (PZCs) in primary maxillary incisors. The retention of PZCs is dependent on the bond strength of luting cement between PZCs and primary maxillary incisors. The aim of this study was to evaluate the tensile bond strengths between PZCs and primary maxillary incisors with different types of luting cements.</p><p><strong>Methods: </strong>Thirty freshly extracted human primary maxillary incisors were prepared and randomly divided into three groups corresponding to three luting cements: bioactive cement, resin cement, and resin-modified glass ionomer cement (RMGIC), and then restored with PZCs. Tensile bond strengths were evaluated by a universal testing machine. The results were analysed using one-way ANOVA with Tukey's post-hoc test (p < 0.05).</p><p><strong>Results: </strong>The means of the tensile bond strengths were 1.43 ± 0.85 MPa, 0.91 ± 0.63 MPa, and 0.56 ± 0.39 MPa for the bioactive cement, resin cement, and RMGIC groups, respectively. A significant difference in tensile bond strength was observed between the bioactive cement and the RMGIC group (p < 0.05) but there was no significant difference in tensile bond strength between the resin cement group and the others.</p><p><strong>Conclusion: </strong>Types of luting cement influenced the tensile bond strength between PZCs and primary maxillary incisors. The bioactive cement showed higher tensile bond strength than the resin cement and RMGIC.</p>","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dental pain in Brazilian preschool children: association with the severity of dental caries and impact on oral health-related quality of life. 巴西学龄前儿童的牙痛:与龋齿严重程度的关系以及对口腔健康相关生活质量的影响。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-05-18 DOI: 10.1007/s40368-024-00906-6
M S Fernandez, L A Pauli, A B G Araújo, G T Demarco, M S Azevedo, V P P da Costa, M L Goettems

Purpose: This study aimed to verify the association between dental pain and severity of dental caries (caries morbidity stages) and the impact on oral health-related quality of life (OHRQoL) in preschool children.

Methods: A cross-sectional study with 199 children (2-5 years old) enrolled at preschools in Capão do Leão-RS, Brazil. The self-report of mothers of children with a history of dental pain in the last 6 months and perception of their child's OHRQoL (ECOHIS) were obtained through a structured questionnaire. This questionnaire also collected independent variables. Children's oral examination was performed using the CAST instrument to determine caries morbidity stage. Crude and adjusted Poisson regression analysis was performed.

Results: The prevalence of dental pain was 14.57%. The chance of the occurrence of dental pain was higher among children diagnosed in morbidity [Prevalence ratio-PR: 5.29 (95% confidence interval-95% CI 1.91-14.61); p = 0.001] and severe morbidity [RP = 6.12 (95 CI% 2.25-16.64); p < 0.001] stages. Children with dental pain presented higher scores in the total ECOHIS [rate ratio = 7.11 (95% CI 4.55-11.09); p < 0.001] and in all of the domains of this instrument. Furthermore, children with a history of dental trauma [PR = 2.41 (95% CI 1.15-5.04); p < 0.001] and those whose reason for last visit to the dental office was for restorative/endodontic/extraction treatment [PR = 1.29 (95% CI 1.01-6.19); p = 0.049] had a higher prevalence of dental pain.

Conclusion: A substantial prevalence of dental pain in the last 6 months and negative impact on children's OHRQoL was identified in this sample. Children diagnosed with carious dentin lesions and abscess and fistula were more likely to have dental pain.

目的:本研究旨在验证牙痛与学龄前儿童龋齿严重程度(龋病发病阶段)之间的关联,以及对口腔健康相关生活质量(OHRQoL)的影响:这是一项横断面研究,研究对象为巴西 Capão do Leão-RS 学龄前学校的 199 名儿童(2-5 岁)。通过结构化问卷调查,获得了在过去 6 个月中有牙痛病史的儿童的母亲的自我报告以及对其子女的 OHRQoL(ECOHIS)的感知。该问卷还收集了自变量。使用 CAST 工具对儿童进行口腔检查,以确定龋病的发病阶段。对结果进行了粗略和调整泊松回归分析:结果:牙痛发生率为 14.57%。在被诊断为发病期的儿童中,发生牙痛的几率更高[患病率比-PR:5.29(95% 置信区间-95% CI 1.91-14.61);P = 0.001],在被诊断为重度发病期的儿童中,发生牙痛的几率更高[RP = 6.12(95% CI% 2.25-16.64);P 结论:在该样本中发现,过去 6 个月中牙痛的发生率很高,对儿童的 OHRQoL 产生了负面影响。被诊断出患有龋齿、脓肿和瘘管的儿童更容易出现牙痛。
{"title":"Dental pain in Brazilian preschool children: association with the severity of dental caries and impact on oral health-related quality of life.","authors":"M S Fernandez, L A Pauli, A B G Araújo, G T Demarco, M S Azevedo, V P P da Costa, M L Goettems","doi":"10.1007/s40368-024-00906-6","DOIUrl":"10.1007/s40368-024-00906-6","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to verify the association between dental pain and severity of dental caries (caries morbidity stages) and the impact on oral health-related quality of life (OHRQoL) in preschool children.</p><p><strong>Methods: </strong>A cross-sectional study with 199 children (2-5 years old) enrolled at preschools in Capão do Leão-RS, Brazil. The self-report of mothers of children with a history of dental pain in the last 6 months and perception of their child's OHRQoL (ECOHIS) were obtained through a structured questionnaire. This questionnaire also collected independent variables. Children's oral examination was performed using the CAST instrument to determine caries morbidity stage. Crude and adjusted Poisson regression analysis was performed.</p><p><strong>Results: </strong>The prevalence of dental pain was 14.57%. The chance of the occurrence of dental pain was higher among children diagnosed in morbidity [Prevalence ratio-PR: 5.29 (95% confidence interval-95% CI 1.91-14.61); p = 0.001] and severe morbidity [RP = 6.12 (95 CI% 2.25-16.64); p < 0.001] stages. Children with dental pain presented higher scores in the total ECOHIS [rate ratio = 7.11 (95% CI 4.55-11.09); p < 0.001] and in all of the domains of this instrument. Furthermore, children with a history of dental trauma [PR = 2.41 (95% CI 1.15-5.04); p < 0.001] and those whose reason for last visit to the dental office was for restorative/endodontic/extraction treatment [PR = 1.29 (95% CI 1.01-6.19); p = 0.049] had a higher prevalence of dental pain.</p><p><strong>Conclusion: </strong>A substantial prevalence of dental pain in the last 6 months and negative impact on children's OHRQoL was identified in this sample. Children diagnosed with carious dentin lesions and abscess and fistula were more likely to have dental pain.</p>","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140960264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypomineralised second primary molars: the Würzburg concept. 下矿化第二初级臼齿:维尔茨堡概念。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-05-28 DOI: 10.1007/s40368-024-00913-7
K Bekes, R Steffen, N Krämer

Purpose: In addition to molar incisor hypomineralisation, the occurrence of enamel hypomineralisation in the primary dentition has become increasingly important in recent years. Hypomineralised second primary molar (HSPM) is defined as hypomineralisation of systemic origin affecting from one to all four second primary molars. Some years ago, the "Würzburg concept" was introduced, which proposed a grading of MIH findings (MIH treatment need index) in combination with an appropriate treatment plan depending on the severity of the affected tooth. Recently, this concept was updated and new treatment approaches have been added. However, currently, the concept solely addresses the treatment plan for permanent teeth. As there is a need to expand its scope to encompass primary teeth and, consequently, HSPM, this paper seeks to develop the second component of the Würzburg concept, the treatment plan, for the primary dentition in response to the increased focus on the disease in recent years. Although the evidence base for the different treatment options is still weak, there is a need for guidance for clinicians in their day-to-day practice.

Methods: The authors conducted a comprehensive review of the literature, encompassing clinical and laboratory studies along with published guidelines.

Results: The treatment plan of the HSPM Würzburg concept contains prophylactic and regenerative aspects, non-invasive interventions, temporary and permanent restorative techniques, and extraction.

Conclusions: The intention is to provide practical guidance to practitioners, acknowledging the necessity for further validation through clinical trials.

目的:除了磨牙切牙低矿化外,近年来基牙釉质低矿化也变得越来越重要。第二乳磨牙低矿化(HSPM)是指影响一颗到全部四颗第二乳磨牙的全身性低矿化。几年前,人们提出了 "维尔茨堡概念",即根据患牙的严重程度,将MIH结果(MIH治疗需求指数)与适当的治疗方案相结合进行分级。最近,这一概念得到了更新,并增加了新的治疗方法。然而,目前这一概念仅针对恒牙的治疗方案。由于有必要将其范围扩大到包括基牙,进而包括 HSPM,本文试图针对近年来人们对该疾病的日益关注,为基牙制定维尔茨堡概念的第二个组成部分,即治疗计划。尽管不同治疗方案的证据基础还很薄弱,但仍有必要为临床医生的日常工作提供指导:作者对文献进行了全面回顾,包括临床和实验室研究以及已出版的指南:结果:维尔茨堡 HSPM 概念的治疗计划包括预防和再生、非侵入性干预、临时和永久性修复技术以及拔牙:结论:本文旨在为从业人员提供实用指导,同时承认有必要通过临床试验进一步验证。
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引用次数: 0
期刊
European Archives of Paediatric Dentistry
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