Pub Date : 2024-08-02DOI: 10.1007/s40368-024-00932-4
M R Tovani-Palone
{"title":"WHO essential medicines for dentistry: a focus on patients with special care needs.","authors":"M R Tovani-Palone","doi":"10.1007/s40368-024-00932-4","DOIUrl":"https://doi.org/10.1007/s40368-024-00932-4","url":null,"abstract":"","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: The variations in interproximal contact areas have been categorised open (O), point (X), straight (I), and curved contact (S). This is based on their shapes and termed as OXIS classification. The interactive OXIS calibration website was developed to assist researchers seeking appropriate knowledge, minimise the overload of material, optimise efficiency in calibration and, to provide repositories for clinicians, healthcare workers, and policymakers.
Methods: The website was developed in two phases. The first phase of development included expert group discussion, Focus Group Discussion (FGD), and the implementation of FGD recommendations. The second phase emphasised registration and development of the interactive web portal on OXIS classification. The developed website was subjected to user experience testing, functional testing, performance testing, security testing, device, platform testing, and then hosted. Calibrated students and faculties evaluated it with the help of Suitability Assessment of Materials (SAM) and System Usability Scale (SUS). Finally, after amendments, the website was evaluated by non-calibrated researchers and multidisciplinary experts.
Results: The total agreement was 74% for overall SAM category. Pooled mean total score of SUS was 52.7 (SD 7.17; range 45-67.5), indicating an average score.
Conclusion: The content of the developed website has been evaluated as "satisfactory" and its technical quality as "of higher standards".
{"title":"Development of 'OXIS Classification' calibration website for dental researchers.","authors":"Tarun Walia, Murugan Satta Muthu, Sneha Suhas Patil, Raghavendra Manjunath Shetty","doi":"10.1007/s40368-024-00908-4","DOIUrl":"10.1007/s40368-024-00908-4","url":null,"abstract":"<p><strong>Purpose: </strong>The variations in interproximal contact areas have been categorised open (O), point (X), straight (I), and curved contact (S). This is based on their shapes and termed as OXIS classification. The interactive OXIS calibration website was developed to assist researchers seeking appropriate knowledge, minimise the overload of material, optimise efficiency in calibration and, to provide repositories for clinicians, healthcare workers, and policymakers.</p><p><strong>Methods: </strong>The website was developed in two phases. The first phase of development included expert group discussion, Focus Group Discussion (FGD), and the implementation of FGD recommendations. The second phase emphasised registration and development of the interactive web portal on OXIS classification. The developed website was subjected to user experience testing, functional testing, performance testing, security testing, device, platform testing, and then hosted. Calibrated students and faculties evaluated it with the help of Suitability Assessment of Materials (SAM) and System Usability Scale (SUS). Finally, after amendments, the website was evaluated by non-calibrated researchers and multidisciplinary experts.</p><p><strong>Results: </strong>The total agreement was 74% for overall SAM category. Pooled mean total score of SUS was 52.7 (SD 7.17; range 45-67.5), indicating an average score.</p><p><strong>Conclusion: </strong>The content of the developed website has been evaluated as \"satisfactory\" and its technical quality as \"of higher standards\".</p>","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140960268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-06-04DOI: 10.1007/s40368-024-00914-6
M S Muthu, A Ganesh, S Anandan, G Thiruvengadam, R Padmanabhan, S Nuvvula
Purpose: Tooth eruption is a dynamic process. Appearance of any part of the cusp through gingiva may be a clinical marker of eruption. Early childhood caries (ECC) is a public health problem globally. This study aimed to assess the relationship between parent-reported timing of first tooth emergence and ECC in toddlers.
Methods: This study is a secondary data analysis of 627 toddlers involved in a case-control study on sleep-time feeding practises in children. The children were categorised into four groups based on the parent-reported timing of first primary tooth emergence (G1-when the first primary tooth emerged before 6 months of age, G2-between 7 and 9 months; G3-10 to 12 months and G4-when the first primary tooth emerged after 12 months of age). Univariate binary logistic regression analysis was performed to evaluate the association between timing of first tooth emergence and ECC.
Results: The mean age of the children was 24.4 ± 7.3 months (cases, that is children with ECC-25.4 ± 6.9 months, controls, that is children without ECC-23.6 ± 7.5 months). Of 60 children, whose first tooth erupted before 6 months of age, 35 (12%) were cases compared to 25(8%) controls. Amongst the cases, boys had more caries than girls (p < 0.05). Of the anterior teeth, 22% of the emerged teeth were decayed in the first group, followed by 19%, 16% and 10% in the second, third and fourth groups, respectively (p < 0.05). Analysis of the posterior teeth showed a lower percentage of decayed teeth with delayed emergence of the first primary tooth (p < 0.05). Children whose teeth emerged before 6 months of age had an odds ratio of 3.5 (95% CI 1.49, 8.42) (p = 0.004).
Conclusion: This study concluded that the early emergence of the first primary tooth, as reported by the parent, was associated with an increased risk of developing ECC.
{"title":"Association of parent-reported timing of first tooth emergence and ECC: a secondary analysis of a case-control study.","authors":"M S Muthu, A Ganesh, S Anandan, G Thiruvengadam, R Padmanabhan, S Nuvvula","doi":"10.1007/s40368-024-00914-6","DOIUrl":"10.1007/s40368-024-00914-6","url":null,"abstract":"<p><strong>Purpose: </strong>Tooth eruption is a dynamic process. Appearance of any part of the cusp through gingiva may be a clinical marker of eruption. Early childhood caries (ECC) is a public health problem globally. This study aimed to assess the relationship between parent-reported timing of first tooth emergence and ECC in toddlers.</p><p><strong>Methods: </strong>This study is a secondary data analysis of 627 toddlers involved in a case-control study on sleep-time feeding practises in children. The children were categorised into four groups based on the parent-reported timing of first primary tooth emergence (G1-when the first primary tooth emerged before 6 months of age, G2-between 7 and 9 months; G3-10 to 12 months and G4-when the first primary tooth emerged after 12 months of age). Univariate binary logistic regression analysis was performed to evaluate the association between timing of first tooth emergence and ECC.</p><p><strong>Results: </strong>The mean age of the children was 24.4 ± 7.3 months (cases, that is children with ECC-25.4 ± 6.9 months, controls, that is children without ECC-23.6 ± 7.5 months). Of 60 children, whose first tooth erupted before 6 months of age, 35 (12%) were cases compared to 25(8%) controls. Amongst the cases, boys had more caries than girls (p < 0.05). Of the anterior teeth, 22% of the emerged teeth were decayed in the first group, followed by 19%, 16% and 10% in the second, third and fourth groups, respectively (p < 0.05). Analysis of the posterior teeth showed a lower percentage of decayed teeth with delayed emergence of the first primary tooth (p < 0.05). Children whose teeth emerged before 6 months of age had an odds ratio of 3.5 (95% CI 1.49, 8.42) (p = 0.004).</p><p><strong>Conclusion: </strong>This study concluded that the early emergence of the first primary tooth, as reported by the parent, was associated with an increased risk of developing ECC.</p>","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-06-06DOI: 10.1007/s40368-024-00911-9
F Rexhaj, N Sabel, A Robertson, T Lundgren
Purpose: The aim of this study was to explore the potential to profile and distinguish varying clinical severity grades of MIH, compared to normal enamel, using proteomics.
Methods: Liquid chromatography-mass spectrometry analyses were conducted on enamel samples of extracted teeth, from 11 children and adolescents, spanning an age range of 6-18 years. Enamel powder samples were collected from extracted, third molars (n = 3) and first permanent molars diagnosed with MIH (n = 8). The MIH tooth samples were categorized into subgroups based on clinical severity grade. The data were statistically analyzed using ANOVA and Welch's t test.
Results: Teeth affected by MIH exhibited a diverse array of proteins, each with different functions related to dental enamel, distinguishing them from their normal enamel counterparts. The application of microdissection combined with LC-MS techniques has revealed the potential to discern unique proteomic profiles among MIH-affected teeth, characterized by varying clinical severity grades. Both analyzed MIH groups displayed consistent trends in the presentation of biological processes, including underabundance of proteins primarily associated with cell organization and biogenesis. Furthermore, proteins linked to cell death were overabundant in both MIH groups.
Conclusion: Proteomics enabled the detection and differentiation of various proteins across different clinical severity grades of MIH.
{"title":"Proteomic profiling of human dental enamel affected by molar incisor hypomineralisation of different clinical severity grades: an in vitro study.","authors":"F Rexhaj, N Sabel, A Robertson, T Lundgren","doi":"10.1007/s40368-024-00911-9","DOIUrl":"10.1007/s40368-024-00911-9","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to explore the potential to profile and distinguish varying clinical severity grades of MIH, compared to normal enamel, using proteomics.</p><p><strong>Methods: </strong>Liquid chromatography-mass spectrometry analyses were conducted on enamel samples of extracted teeth, from 11 children and adolescents, spanning an age range of 6-18 years. Enamel powder samples were collected from extracted, third molars (n = 3) and first permanent molars diagnosed with MIH (n = 8). The MIH tooth samples were categorized into subgroups based on clinical severity grade. The data were statistically analyzed using ANOVA and Welch's t test.</p><p><strong>Results: </strong>Teeth affected by MIH exhibited a diverse array of proteins, each with different functions related to dental enamel, distinguishing them from their normal enamel counterparts. The application of microdissection combined with LC-MS techniques has revealed the potential to discern unique proteomic profiles among MIH-affected teeth, characterized by varying clinical severity grades. Both analyzed MIH groups displayed consistent trends in the presentation of biological processes, including underabundance of proteins primarily associated with cell organization and biogenesis. Furthermore, proteins linked to cell death were overabundant in both MIH groups.</p><p><strong>Conclusion: </strong>Proteomics enabled the detection and differentiation of various proteins across different clinical severity grades of MIH.</p>","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11341683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-07-05DOI: 10.1007/s40368-024-00919-1
T S de Macêdo, M C F de Melo, A K A Ferreira, E L M S da Silva-Selva, G P Godoy, A de F Caldas Júnior
Purpose: This study aimed to analyze, through a hierarchical model, the risk factors associated with the recurrence of chemo-induced oral mucositis (OM) in children and adolescents.
Methods: A retrospective cohort with 31 individuals of both sexes, aged 1-18 years, who were undergoing chemotherapy, and presented OM lesions was conducted. Data collection included analysis of medical records, interviews, and intraoral examination. Information regarding patients' socioeconomic and demographic profile, underlying disease, antineoplastic regimen, hematological condition, and oral health status were collected. To assess the association of independent variables with the outcome, the Chi-square, Fisher's Exact, and Mann-Whitney tests were used, in addition to a binary logistic regression model, with a maximum error of 5% and a 95% confidence interval.
Results: Significant associations were observed between the history of OM and the diagnosis of the child/adolescent, neutrophil count, previous cancer treatments and the chemotherapy scheme in use (p < 0.05). Binary logistic regression revealed a 13.69 higher risk of developing OM recurrence in individuals who received high-dose methotrexate (MTX) therapy.
Conclusion: Socioeconomic and demographic factors did not influence OM recurrence. However, clinical variables, such as neutropenia, diagnosis of leukemia, and high-dose MTX protocols increase the chance of OM new cases.
目的:本研究旨在通过层次模型分析与儿童和青少年化疗引起的口腔黏膜炎(OM)复发相关的风险因素:方法:对 31 名正在接受化疗并出现口腔黏膜炎病变的 1-18 岁男女患者进行了回顾性队列研究。数据收集包括病历分析、访谈和口腔内检查。收集的信息涉及患者的社会经济和人口概况、基础疾病、抗肿瘤疗法、血液状况和口腔健康状况。为了评估自变量与结果之间的关系,除了使用二元逻辑回归模型(最大误差为 5%,置信区间为 95%)外,还使用了卡方检验(Chi-square)、费雪精确检验(Fisher's Exact)和曼惠特尼检验(Mann-Whitney):观察发现,OM 病史与儿童/青少年的诊断、中性粒细胞计数、既往癌症治疗和正在使用的化疗方案之间存在显著关联(p 结论:OM 病史与儿童/青少年的诊断、中性粒细胞计数、既往癌症治疗和正在使用的化疗方案之间存在显著关联:社会经济和人口学因素不会影响 OM 复发。然而,中性粒细胞减少症、白血病诊断和大剂量 MTX 方案等临床变量会增加 OM 新病例的发生几率。
{"title":"Chemotherapy-induced oral mucositis: hierarchical analysis of recurrence factors.","authors":"T S de Macêdo, M C F de Melo, A K A Ferreira, E L M S da Silva-Selva, G P Godoy, A de F Caldas Júnior","doi":"10.1007/s40368-024-00919-1","DOIUrl":"10.1007/s40368-024-00919-1","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to analyze, through a hierarchical model, the risk factors associated with the recurrence of chemo-induced oral mucositis (OM) in children and adolescents.</p><p><strong>Methods: </strong>A retrospective cohort with 31 individuals of both sexes, aged 1-18 years, who were undergoing chemotherapy, and presented OM lesions was conducted. Data collection included analysis of medical records, interviews, and intraoral examination. Information regarding patients' socioeconomic and demographic profile, underlying disease, antineoplastic regimen, hematological condition, and oral health status were collected. To assess the association of independent variables with the outcome, the Chi-square, Fisher's Exact, and Mann-Whitney tests were used, in addition to a binary logistic regression model, with a maximum error of 5% and a 95% confidence interval.</p><p><strong>Results: </strong>Significant associations were observed between the history of OM and the diagnosis of the child/adolescent, neutrophil count, previous cancer treatments and the chemotherapy scheme in use (p < 0.05). Binary logistic regression revealed a 13.69 higher risk of developing OM recurrence in individuals who received high-dose methotrexate (MTX) therapy.</p><p><strong>Conclusion: </strong>Socioeconomic and demographic factors did not influence OM recurrence. However, clinical variables, such as neutropenia, diagnosis of leukemia, and high-dose MTX protocols increase the chance of OM new cases.</p>","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141538727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-06-26DOI: 10.1007/s40368-024-00912-8
Y Y L Lai, J Downs, S Leishman, H M Leonard, L J Walsh, S Zafar
Purpose: This study aimed to validate qPCR assays for specific microbiota, for use on dental plaque samples stored on Whatman FTA cards to compare relative oral health risk in Rett syndrome.
Methods: Supragingival dental plaque samples were collected, using a sterile swab, (COPAN FLOQswab™) swabbed onto Whatman FTA™ cards. DNA extraction was performed using a modified Powersoil™ protocol. Where published assays were unsuitable, species-specific qPCR assays for caries-associated, gingivitis-associated and oral-health-associated bacteria were designed using multiple sequence alignment, Primer3Plus and PrimerQuest. Assays were run using absolute quantification. Limit of detection (LOD) and limit of quantification (LOQ) were calculated, and PCR products verified by Sanger sequencing.
Results: Most assays allowed detection using real-time qPCR with high specificity on samples collected on FTA cards. Several assays showed low or even single gene copy numbers on the test samples.
Conclusion: Assays were optimised for detection and evaluation of oral health risk in dental plaque samples stored on FTA cards when cold storage is not feasible, except for F. nucleatum. Several assays showed gene copy numbers less than the LOQ or outside the range of the standard curve, so there is merit in optimising these assays using digital droplet PCR.
{"title":"qPCR assay optimisation for a clinical study comparing oral health risk in Rett syndrome.","authors":"Y Y L Lai, J Downs, S Leishman, H M Leonard, L J Walsh, S Zafar","doi":"10.1007/s40368-024-00912-8","DOIUrl":"10.1007/s40368-024-00912-8","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to validate qPCR assays for specific microbiota, for use on dental plaque samples stored on Whatman FTA cards to compare relative oral health risk in Rett syndrome.</p><p><strong>Methods: </strong>Supragingival dental plaque samples were collected, using a sterile swab, (COPAN FLOQswab™) swabbed onto Whatman FTA™ cards. DNA extraction was performed using a modified Powersoil™ protocol. Where published assays were unsuitable, species-specific qPCR assays for caries-associated, gingivitis-associated and oral-health-associated bacteria were designed using multiple sequence alignment, Primer3Plus and PrimerQuest. Assays were run using absolute quantification. Limit of detection (LOD) and limit of quantification (LOQ) were calculated, and PCR products verified by Sanger sequencing.</p><p><strong>Results: </strong>Most assays allowed detection using real-time qPCR with high specificity on samples collected on FTA cards. Several assays showed low or even single gene copy numbers on the test samples.</p><p><strong>Conclusion: </strong>Assays were optimised for detection and evaluation of oral health risk in dental plaque samples stored on FTA cards when cold storage is not feasible, except for F. nucleatum. Several assays showed gene copy numbers less than the LOQ or outside the range of the standard curve, so there is merit in optimising these assays using digital droplet PCR.</p>","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11341660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141459920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-04-26DOI: 10.1007/s40368-024-00903-9
M Brejawi, A Venkiteswaran, S M O Ergieg, B Md Sabri
{"title":"The need for a comprehensive case-severity-grading tool for molar-incisor hypomineralisation (MIH).","authors":"M Brejawi, A Venkiteswaran, S M O Ergieg, B Md Sabri","doi":"10.1007/s40368-024-00903-9","DOIUrl":"10.1007/s40368-024-00903-9","url":null,"abstract":"","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-04-12DOI: 10.1007/s40368-024-00890-x
P Pengpue, V Sirimaharaj, P Chaijareenont, W Chinadet
Purpose: There is limited evidence regarding the most appropriate type of luting cement for paediatric prefabricated zirconia crowns (PZCs) in primary maxillary incisors. The retention of PZCs is dependent on the bond strength of luting cement between PZCs and primary maxillary incisors. The aim of this study was to evaluate the tensile bond strengths between PZCs and primary maxillary incisors with different types of luting cements.
Methods: Thirty freshly extracted human primary maxillary incisors were prepared and randomly divided into three groups corresponding to three luting cements: bioactive cement, resin cement, and resin-modified glass ionomer cement (RMGIC), and then restored with PZCs. Tensile bond strengths were evaluated by a universal testing machine. The results were analysed using one-way ANOVA with Tukey's post-hoc test (p < 0.05).
Results: The means of the tensile bond strengths were 1.43 ± 0.85 MPa, 0.91 ± 0.63 MPa, and 0.56 ± 0.39 MPa for the bioactive cement, resin cement, and RMGIC groups, respectively. A significant difference in tensile bond strength was observed between the bioactive cement and the RMGIC group (p < 0.05) but there was no significant difference in tensile bond strength between the resin cement group and the others.
Conclusion: Types of luting cement influenced the tensile bond strength between PZCs and primary maxillary incisors. The bioactive cement showed higher tensile bond strength than the resin cement and RMGIC.
{"title":"Tensile bond strength between paediatric prefabricated zirconia crowns and primary maxillary incisors when using various types of luting cements: an in vitro study.","authors":"P Pengpue, V Sirimaharaj, P Chaijareenont, W Chinadet","doi":"10.1007/s40368-024-00890-x","DOIUrl":"10.1007/s40368-024-00890-x","url":null,"abstract":"<p><strong>Purpose: </strong>There is limited evidence regarding the most appropriate type of luting cement for paediatric prefabricated zirconia crowns (PZCs) in primary maxillary incisors. The retention of PZCs is dependent on the bond strength of luting cement between PZCs and primary maxillary incisors. The aim of this study was to evaluate the tensile bond strengths between PZCs and primary maxillary incisors with different types of luting cements.</p><p><strong>Methods: </strong>Thirty freshly extracted human primary maxillary incisors were prepared and randomly divided into three groups corresponding to three luting cements: bioactive cement, resin cement, and resin-modified glass ionomer cement (RMGIC), and then restored with PZCs. Tensile bond strengths were evaluated by a universal testing machine. The results were analysed using one-way ANOVA with Tukey's post-hoc test (p < 0.05).</p><p><strong>Results: </strong>The means of the tensile bond strengths were 1.43 ± 0.85 MPa, 0.91 ± 0.63 MPa, and 0.56 ± 0.39 MPa for the bioactive cement, resin cement, and RMGIC groups, respectively. A significant difference in tensile bond strength was observed between the bioactive cement and the RMGIC group (p < 0.05) but there was no significant difference in tensile bond strength between the resin cement group and the others.</p><p><strong>Conclusion: </strong>Types of luting cement influenced the tensile bond strength between PZCs and primary maxillary incisors. The bioactive cement showed higher tensile bond strength than the resin cement and RMGIC.</p>","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-05-18DOI: 10.1007/s40368-024-00906-6
M S Fernandez, L A Pauli, A B G Araújo, G T Demarco, M S Azevedo, V P P da Costa, M L Goettems
Purpose: This study aimed to verify the association between dental pain and severity of dental caries (caries morbidity stages) and the impact on oral health-related quality of life (OHRQoL) in preschool children.
Methods: A cross-sectional study with 199 children (2-5 years old) enrolled at preschools in Capão do Leão-RS, Brazil. The self-report of mothers of children with a history of dental pain in the last 6 months and perception of their child's OHRQoL (ECOHIS) were obtained through a structured questionnaire. This questionnaire also collected independent variables. Children's oral examination was performed using the CAST instrument to determine caries morbidity stage. Crude and adjusted Poisson regression analysis was performed.
Results: The prevalence of dental pain was 14.57%. The chance of the occurrence of dental pain was higher among children diagnosed in morbidity [Prevalence ratio-PR: 5.29 (95% confidence interval-95% CI 1.91-14.61); p = 0.001] and severe morbidity [RP = 6.12 (95 CI% 2.25-16.64); p < 0.001] stages. Children with dental pain presented higher scores in the total ECOHIS [rate ratio = 7.11 (95% CI 4.55-11.09); p < 0.001] and in all of the domains of this instrument. Furthermore, children with a history of dental trauma [PR = 2.41 (95% CI 1.15-5.04); p < 0.001] and those whose reason for last visit to the dental office was for restorative/endodontic/extraction treatment [PR = 1.29 (95% CI 1.01-6.19); p = 0.049] had a higher prevalence of dental pain.
Conclusion: A substantial prevalence of dental pain in the last 6 months and negative impact on children's OHRQoL was identified in this sample. Children diagnosed with carious dentin lesions and abscess and fistula were more likely to have dental pain.
{"title":"Dental pain in Brazilian preschool children: association with the severity of dental caries and impact on oral health-related quality of life.","authors":"M S Fernandez, L A Pauli, A B G Araújo, G T Demarco, M S Azevedo, V P P da Costa, M L Goettems","doi":"10.1007/s40368-024-00906-6","DOIUrl":"10.1007/s40368-024-00906-6","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to verify the association between dental pain and severity of dental caries (caries morbidity stages) and the impact on oral health-related quality of life (OHRQoL) in preschool children.</p><p><strong>Methods: </strong>A cross-sectional study with 199 children (2-5 years old) enrolled at preschools in Capão do Leão-RS, Brazil. The self-report of mothers of children with a history of dental pain in the last 6 months and perception of their child's OHRQoL (ECOHIS) were obtained through a structured questionnaire. This questionnaire also collected independent variables. Children's oral examination was performed using the CAST instrument to determine caries morbidity stage. Crude and adjusted Poisson regression analysis was performed.</p><p><strong>Results: </strong>The prevalence of dental pain was 14.57%. The chance of the occurrence of dental pain was higher among children diagnosed in morbidity [Prevalence ratio-PR: 5.29 (95% confidence interval-95% CI 1.91-14.61); p = 0.001] and severe morbidity [RP = 6.12 (95 CI% 2.25-16.64); p < 0.001] stages. Children with dental pain presented higher scores in the total ECOHIS [rate ratio = 7.11 (95% CI 4.55-11.09); p < 0.001] and in all of the domains of this instrument. Furthermore, children with a history of dental trauma [PR = 2.41 (95% CI 1.15-5.04); p < 0.001] and those whose reason for last visit to the dental office was for restorative/endodontic/extraction treatment [PR = 1.29 (95% CI 1.01-6.19); p = 0.049] had a higher prevalence of dental pain.</p><p><strong>Conclusion: </strong>A substantial prevalence of dental pain in the last 6 months and negative impact on children's OHRQoL was identified in this sample. Children diagnosed with carious dentin lesions and abscess and fistula were more likely to have dental pain.</p>","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140960264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-05-28DOI: 10.1007/s40368-024-00913-7
K Bekes, R Steffen, N Krämer
Purpose: In addition to molar incisor hypomineralisation, the occurrence of enamel hypomineralisation in the primary dentition has become increasingly important in recent years. Hypomineralised second primary molar (HSPM) is defined as hypomineralisation of systemic origin affecting from one to all four second primary molars. Some years ago, the "Würzburg concept" was introduced, which proposed a grading of MIH findings (MIH treatment need index) in combination with an appropriate treatment plan depending on the severity of the affected tooth. Recently, this concept was updated and new treatment approaches have been added. However, currently, the concept solely addresses the treatment plan for permanent teeth. As there is a need to expand its scope to encompass primary teeth and, consequently, HSPM, this paper seeks to develop the second component of the Würzburg concept, the treatment plan, for the primary dentition in response to the increased focus on the disease in recent years. Although the evidence base for the different treatment options is still weak, there is a need for guidance for clinicians in their day-to-day practice.
Methods: The authors conducted a comprehensive review of the literature, encompassing clinical and laboratory studies along with published guidelines.
Results: The treatment plan of the HSPM Würzburg concept contains prophylactic and regenerative aspects, non-invasive interventions, temporary and permanent restorative techniques, and extraction.
Conclusions: The intention is to provide practical guidance to practitioners, acknowledging the necessity for further validation through clinical trials.
{"title":"Hypomineralised second primary molars: the Würzburg concept.","authors":"K Bekes, R Steffen, N Krämer","doi":"10.1007/s40368-024-00913-7","DOIUrl":"10.1007/s40368-024-00913-7","url":null,"abstract":"<p><strong>Purpose: </strong>In addition to molar incisor hypomineralisation, the occurrence of enamel hypomineralisation in the primary dentition has become increasingly important in recent years. Hypomineralised second primary molar (HSPM) is defined as hypomineralisation of systemic origin affecting from one to all four second primary molars. Some years ago, the \"Würzburg concept\" was introduced, which proposed a grading of MIH findings (MIH treatment need index) in combination with an appropriate treatment plan depending on the severity of the affected tooth. Recently, this concept was updated and new treatment approaches have been added. However, currently, the concept solely addresses the treatment plan for permanent teeth. As there is a need to expand its scope to encompass primary teeth and, consequently, HSPM, this paper seeks to develop the second component of the Würzburg concept, the treatment plan, for the primary dentition in response to the increased focus on the disease in recent years. Although the evidence base for the different treatment options is still weak, there is a need for guidance for clinicians in their day-to-day practice.</p><p><strong>Methods: </strong>The authors conducted a comprehensive review of the literature, encompassing clinical and laboratory studies along with published guidelines.</p><p><strong>Results: </strong>The treatment plan of the HSPM Würzburg concept contains prophylactic and regenerative aspects, non-invasive interventions, temporary and permanent restorative techniques, and extraction.</p><p><strong>Conclusions: </strong>The intention is to provide practical guidance to practitioners, acknowledging the necessity for further validation through clinical trials.</p>","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11341634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}