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OXIS contacts of primary molars: do they change over time? 初级臼齿的 OXIS 接触点:会随时间变化吗?
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-07-05 DOI: 10.1007/s40368-024-00924-4
M S Muthu, M Kirthiga, A Saikia

Purpose: Although a series of studies on OXIS contacts have been performed, studies regarding changes in OXIS contacts over time are lacking. Therefore, this study aimed to evaluate the change in contact type between primary molars after 3 years in children aged 3-7 years.

Methods: This longitudinal study was conducted using 2922 sectional die models of 926 children. At baseline (T0), the contact type between the primary molars was scored using replication via the sectional die model method according to the OXIS criteria. After 3 years, the sectional die models of the same children were scored using the same criteria (T1).

Results: McNemar's tests revealed a significant change in contacts from baseline to 3 years. The post hoc test explained specific changes in the contacts that were observed to be significant. These were O to X (p < 0.001), O to I (p < 0.001), O to S (p = 0.035), and I to X (p < 0.001).

Conclusions: A significant change in OXIS contact over time was observed. The O-type contact underwent the maximum change. The least and most stable contacts are the "O" and "I" types, respectively. This change in contact type with age may alter the risk of caries in children.

目的:虽然已经开展了一系列关于OXIS接触的研究,但缺乏关于OXIS接触随时间变化的研究。因此,本研究旨在评估 3-7 岁儿童 3 年后基磨牙间接触类型的变化:这项纵向研究使用了 926 名儿童的 2922 个切面模型。在基线(T0)时,根据 OXIS 标准,通过截面模型复制法对初级臼齿之间的接触类型进行评分。3 年后,采用相同的标准对同一儿童的截面模型进行评分(T1):McNemar 检验显示,从基线到 3 年期间,接触点发生了显著变化。事后检验解释了接触中观察到的显著变化。这些变化是 O 到 X 的变化(P 结论):观察到随着时间的推移,OXIS 接触发生了重大变化。O 型接触变化最大。最不稳定和最稳定的接触分别是 "O "型和 "I "型。接触类型随年龄的变化可能会改变儿童患龋的风险。
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引用次数: 0
Assessing robustness of results of randomised clinical trials using Fragility Index. 使用脆性指数评估随机临床试验结果的稳健性。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-08-02 DOI: 10.1007/s40368-024-00930-6
S M H Nainar
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引用次数: 0
"Association between caries in anterior teeth and bullying victimization in Brazilian schoolchildren aged 6 to 10 years.: a cross sectional study". "巴西 6 至 10 岁学龄儿童前牙龋齿与欺凌行为之间的关系:一项横断面研究"。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-09-13 DOI: 10.1007/s40368-024-00933-3
P G Fonseca, E P S Neves, M E C Soares, R Galo, M L Ramos-Jorge, I B Fernandes

Aim: To investigate the association between presence of caries in anterior teeth and bullying victimization in schoolchildren.

Methods: A cross-sectional study was conducted in Brazil with a sample of 387 schoolchildren aged 6 to 10 years. The presence of moderate/extensive dental caries was assessed using the International System for the Evaluation and Detection of Dental Caries (ICDAS-II). The children answered the "Olweus Bullying" (QBO). Descriptive analyses were performed, and the associations between bullying victimization and independent variables collected were determined by univariate and multivariate Poisson regression.

Results: The prevalence of bullying victimization was 66.4%. Bullying victimization was higher among children who had moderate/extensive caries in some anterior teeth (p = 0.010). 8-year-old (p = 0.048), 9-year-old (p = 0.001), and 10-year-old (p = 0.002) children reported greater bullying victimization when compared to 6-year-olds.

Conclusion: The presence of moderate/extensive dental caries in anterior teeth is associated with bullying victimization in schoolchildren.

目的:研究学龄儿童前牙龋齿与欺凌行为之间的关系:在巴西对 387 名 6 至 10 岁的学龄儿童进行了横断面研究。采用国际龋齿评估和检测系统(ICDAS-II)评估是否存在中度/大面积龋齿。孩子们还回答了 "奥尔维斯欺凌"(QBO)问题。研究人员进行了描述性分析,并通过单变量和多变量泊松回归确定了欺凌受害情况与所收集的自变量之间的关联:结果:受欺凌的发生率为 66.4%。部分前牙有中度/重度龋齿的儿童遭受欺凌的比例更高(p = 0.010)。与 6 岁儿童相比,8 岁(p = 0.048)、9 岁(p = 0.001)和 10 岁(p = 0.002)儿童遭受欺凌的程度更高:结论:前牙中度/大面积龋齿与学龄儿童遭受欺凌有关。
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引用次数: 0
Investigating the impact of surface treatments on tensile bond strength between pediatric prefabricated zirconia crowns and primary maxillary incisors with various types of luting cement: an in vitro study. 调查表面处理对儿科预制氧化锆牙冠和上颌原切牙与各种类型粘结水泥之间拉伸粘结强度的影响:一项体外研究。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-07-24 DOI: 10.1007/s40368-024-00926-2
W Chinadet, P Pengpue, P Chaijareenont

Purpose: This study aimed to evaluate the effects of two surface treatments on the tensile bond strength of prefabricated zirconia crowns (PZCs) using bioactive and resin cements.

Methods: Forty extracted human primary maxillary incisors were prepared and divided into four groups based on surface treatment and cement type: (1) sandblast with bioactive cement, (2) sandblast with resin cement, (3) 10-methacryloyloxydecyl dihydrogen phosphate (10-MDP) with bioactive cement, and (4) 10-MDP with resin cement. After 24 h of cementation, specimens underwent 5000 thermocycling cycles between 5 °C and 55 °C. Tensile bond strengths were measured using a universal testing machine. The data were analyzed using two-way ANOVA and Tukey's post hoc test, with significance set at p < 0.05.

Results: The mean tensile bond strengths observed were 2.25 ± 1.27 MPa for sandblast with bioactive cement, 1.39 ± 0.95 MPa for sandblast with resin cement, 2.45 ± 1.15 MPa for 10-MDP with bioactive cement, and 1.68 ± 1.03 MPa for 10-MDP with resin cement. Significant improvements in bond strength were observed in the bioactive cement group treated with 10-MDP compared to those treated with sandblasting (p < 0.05). The 10-MDP treatment did not enhance bond strength for the resin cement compared to sandblasting.

Conclusions: Bioactive cement generally provides a higher tensile bond strength than resin cement. While 10-MDP treatment enhances bond strength when used with bioactive cement, it does not show a similar enhancement when used with resin cement compared to sandblasting, indicating its effectiveness is selective based on the type of cement used.

目的:本研究旨在评估两种表面处理方法对使用生物活性水门汀和树脂水门汀的预制氧化锆冠(PZC)拉伸粘结强度的影响:制备 40 颗拔出的人类上颌原切牙,并根据表面处理和骨水泥类型分为四组:(1) 喷砂加生物活性骨水泥;(2) 喷砂加树脂骨水泥;(3) 10-甲基丙烯酰氧癸基磷酸二氢酯(10-MDP)加生物活性骨水泥;(4) 10-MDP加树脂骨水泥。粘接 24 小时后,试样在 5 °C 和 55 °C 之间进行 5000 次热循环。使用万能试验机测量拉伸粘结强度。采用双向方差分析和 Tukey 后检验对数据进行分析,显著性以 p 为标准:观察到的平均拉伸粘接强度分别为:喷砂加生物活性水泥为 2.25 ± 1.27 兆帕;喷砂加树脂水泥为 1.39 ± 0.95 兆帕;10-MDP 加生物活性水泥为 2.45 ± 1.15 兆帕;10-MDP 加树脂水泥为 1.68 ± 1.03 兆帕。与喷砂处理组相比,用 10-MDP 处理的生物活性水门汀组的粘结强度明显提高(p 结论:生物活性水门汀通常能提供更高的粘结强度:生物活性水门汀的拉伸粘结强度通常高于树脂水门汀。虽然 10-MDP 处理与生物活性水泥一起使用时能提高粘接强度,但与喷砂处理相比,与树脂水泥一起使用时却没有类似的提高,这表明 10-MDP 的有效性是根据所使用的水泥类型来选择的。
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引用次数: 0
What do Brazilian paediatric dentists know about bruxism in children? Cross-sectional study. 巴西儿童牙医对儿童磨牙症了解多少?横断面研究。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-08-16 DOI: 10.1007/s40368-024-00929-z
A K M de Sena, M de Sá Nass, I O Castro, P Corrêa-Faria

Purpose: Little is known about the knowledge of paediatric dentists on bruxism in children. The aim of this cross-sectional study was to assess the knowledge of paediatric dentists on the concept, associated factors of bruxism and management of sleep bruxism (SB) in children'.

Methods: An electronic questionnaire was sent to paediatric dentists in the state of Goiás, Brazil. Information was collected on (1) characteristics of the participants; (2) the concept of bruxism; (3) diagnosis; (4) associated factors; (5) strategies for the management of SB; and (6) updated knowledge on bruxism in children. The data were analysed descriptively.

Results: Fifty-seven paediatric dentists participated (10.7% of the total number of professionals). A high level of agreement was found with statements on the concepts of SB (94.7%) and awake bruxism (96.5%). The main strategy for the diagnosis was the combination of a parental report and a clinical examination (79.0%). Most participants indicated that bruxism is associated with anxiety/stress (96.5%), screen use (93%), airway obstruction (91.2%), and sleep apnoea (91.2%). In suspected cases of bruxism, the dentists would send the child for assessment by other health care providers (87.7%). The management options frequently indicated were the use of an occlusal splint, aromatherapy, and homeopathy. More than 70% of them considered themselves to be updated on the issue and sought information through scientific articles and discussions with colleagues.

Conclusion: Paediatric dentists have knowledge on the concept of bruxism and associated factors. However, further information is needed on the management of this condition in children.

目的:人们对儿童牙科医生关于儿童磨牙症的知识知之甚少。这项横断面研究旨在评估儿科牙医对磨牙症的概念、相关因素以及儿童睡眠磨牙症(SB)治疗方法的了解程度:向巴西戈亚斯州的儿科牙医发送了一份电子问卷。收集的信息包括:(1) 参与者的特征;(2) 磨牙症的概念;(3) 诊断;(4) 相关因素;(5) 处理 SB 的策略;(6) 有关儿童磨牙症的最新知识。对数据进行了描述性分析:57名儿童牙医参加了此次调查(占专业人员总数的10.7%)。他们对 SB(94.7%)和清醒磨牙症(96.5%)概念的表述高度一致。诊断的主要策略是结合家长报告和临床检查(79.0%)。大多数参与者表示,磨牙症与焦虑/压力(96.5%)、屏幕使用(93%)、气道阻塞(91.2%)和睡眠呼吸暂停(91.2%)有关。在怀疑有磨牙症的情况下,牙医会让儿童接受其他医护人员的评估(87.7%)。常用的治疗方法包括使用咬合夹板、芳香疗法和顺势疗法。超过 70% 的牙医认为自己了解这方面的最新情况,并通过科学文章和与同事的讨论来获取信息:结论:儿童牙医对磨牙症的概念和相关因素有所了解。结论:儿童牙医对磨牙症的概念和相关因素有所了解,但还需要进一步了解儿童磨牙症的治疗方法。
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引用次数: 0
Desensitization treatment in MIH-affected teeth: a systematic review. 受 MIH 影响的牙齿的脱敏治疗:系统综述。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-13 DOI: 10.1007/s40368-024-00934-2
Ebba Hjertberg, Adnan Hajdarević, Birgitta Jälevik

Purpose: The present systematic review aims to summarize the current evidence regarding various treatment modalities and their results when dealing with hypersensitivity in teeth with Molar-Incisor Hypomineralization (MIH).

Methods: Systematic searches were conducted in PubMed and Scopus using the search terms "MIH AND Hypersensitivity AND treatment." Studies involving children aged 6-18 years diagnosed with MIH and exhibiting hypersensitivity were considered for inclusion. The outcomes examined included clinical, behavioral, and psychosocial treatment options for reducing hypersensitivity. A meta-analysis was performed for six of the included articles, and the I2 value was calculated to determine heterogeneity.

Results: A total of eight articles met the inclusion criteria for this review, with six eligible for the meta-analysis. Various treatment modalities, such as dental mousse, sealing, laser therapy, and crown therapy, demonstrated significant reductions in hypersensitivity individually (p < 0.05).

Conclusion: The treatment methods that offer the most effective reduction in hypersensitivity are sealing with resin composite or glass ionomer cement for mild cases of MIH, while crown therapy is more effective for severe cases of MIH. However, the small number of participants and short follow-up times limit the strength of these conclusions.

目的:本系统性综述旨在总结在处理臼齿嵌合体低矿化(MIH)牙齿过敏症时各种治疗方法及其效果的现有证据:方法:在 PubMed 和 Scopus 中使用 "MIH、过敏、治疗 "进行系统检索。涉及 6-18 岁确诊为 MIH 并表现出过敏症的儿童的研究均被考虑纳入。研究结果包括降低过敏性的临床、行为和社会心理治疗方案。对纳入的六篇文章进行了荟萃分析,并计算了 I2 值以确定异质性:共有八篇文章符合本综述的纳入标准,其中六篇符合荟萃分析的条件。各种治疗方法,如牙科摩丝、封闭、激光治疗和牙冠治疗,都能显著降低单个患者的超敏反应(p 结论:最能有效降低过敏性的治疗方法是用树脂复合材料或玻璃离子粘结剂封闭轻度 MIH 病例,而牙冠疗法对重度 MIH 病例更有效。然而,由于参与人数少、随访时间短,这些结论的力度受到限制。
{"title":"Desensitization treatment in MIH-affected teeth: a systematic review.","authors":"Ebba Hjertberg, Adnan Hajdarević, Birgitta Jälevik","doi":"10.1007/s40368-024-00934-2","DOIUrl":"https://doi.org/10.1007/s40368-024-00934-2","url":null,"abstract":"<p><strong>Purpose: </strong>The present systematic review aims to summarize the current evidence regarding various treatment modalities and their results when dealing with hypersensitivity in teeth with Molar-Incisor Hypomineralization (MIH).</p><p><strong>Methods: </strong>Systematic searches were conducted in PubMed and Scopus using the search terms \"MIH AND Hypersensitivity AND treatment.\" Studies involving children aged 6-18 years diagnosed with MIH and exhibiting hypersensitivity were considered for inclusion. The outcomes examined included clinical, behavioral, and psychosocial treatment options for reducing hypersensitivity. A meta-analysis was performed for six of the included articles, and the I<sup>2</sup> value was calculated to determine heterogeneity.</p><p><strong>Results: </strong>A total of eight articles met the inclusion criteria for this review, with six eligible for the meta-analysis. Various treatment modalities, such as dental mousse, sealing, laser therapy, and crown therapy, demonstrated significant reductions in hypersensitivity individually (p < 0.05).</p><p><strong>Conclusion: </strong>The treatment methods that offer the most effective reduction in hypersensitivity are sealing with resin composite or glass ionomer cement for mild cases of MIH, while crown therapy is more effective for severe cases of MIH. However, the small number of participants and short follow-up times limit the strength of these conclusions.</p>","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proteomic profiling of human dental enamel affected by molar incisor hypomineralisation of different clinical severity grades: an in vitro study. 不同临床严重程度的磨牙切牙低矿化所影响的人类牙釉质的蛋白质组分析:一项体外研究。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-06-06 DOI: 10.1007/s40368-024-00911-9
F Rexhaj, N Sabel, A Robertson, T Lundgren

Purpose: The aim of this study was to explore the potential to profile and distinguish varying clinical severity grades of MIH, compared to normal enamel, using proteomics.

Methods: Liquid chromatography-mass spectrometry analyses were conducted on enamel samples of extracted teeth, from 11 children and adolescents, spanning an age range of 6-18 years. Enamel powder samples were collected from extracted, third molars (n = 3) and first permanent molars diagnosed with MIH (n = 8). The MIH tooth samples were categorized into subgroups based on clinical severity grade. The data were statistically analyzed using ANOVA and Welch's t test.

Results: Teeth affected by MIH exhibited a diverse array of proteins, each with different functions related to dental enamel, distinguishing them from their normal enamel counterparts. The application of microdissection combined with LC-MS techniques has revealed the potential to discern unique proteomic profiles among MIH-affected teeth, characterized by varying clinical severity grades. Both analyzed MIH groups displayed consistent trends in the presentation of biological processes, including underabundance of proteins primarily associated with cell organization and biogenesis. Furthermore, proteins linked to cell death were overabundant in both MIH groups.

Conclusion: Proteomics enabled the detection and differentiation of various proteins across different clinical severity grades of MIH.

目的:本研究的目的是利用蛋白质组学的方法,探讨与正常牙釉质相比,对不同临床严重程度的MIH进行剖析和区分的可能性:对 11 名 6-18 岁儿童和青少年的拔牙珐琅质样本进行了液相色谱-质谱分析。珐琅质粉末样本取自被诊断为MIH的拔出第三磨牙(3颗)和第一恒磨牙(8颗)。根据临床严重程度将 MIH 牙齿样本分为不同的亚组。采用方差分析和韦尔奇 t 检验对数据进行统计分析:结果:受MIH影响的牙齿表现出多种多样的蛋白质,每种蛋白质都具有与牙釉质相关的不同功能,使它们有别于正常的牙釉质。显微切割结合 LC-MS 技术的应用揭示了在受 MIH 影响的牙齿中发现独特蛋白质组图谱的潜力,这些图谱以不同的临床严重程度等级为特征。两组受分析的 MIH 患者在生物过程的表现上呈现出一致的趋势,包括主要与细胞组织和生物生成相关的蛋白质含量不足。此外,与细胞死亡有关的蛋白质在两组 MIH 中都过量存在:蛋白质组学能够检测和区分不同临床严重程度等级的 MIH 中的各种蛋白质。
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引用次数: 0
Development of 'OXIS Classification' calibration website for dental researchers. 为牙科研究人员开发 "OXIS 分类 "校准网站。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-05-19 DOI: 10.1007/s40368-024-00908-4
Tarun Walia, Murugan Satta Muthu, Sneha Suhas Patil, Raghavendra Manjunath Shetty

Purpose: The variations in interproximal contact areas have been categorised open (O), point (X), straight (I), and curved contact (S). This is based on their shapes and termed as OXIS classification. The interactive OXIS calibration website was developed to assist researchers seeking appropriate knowledge, minimise the overload of material, optimise efficiency in calibration and, to provide repositories for clinicians, healthcare workers, and policymakers.

Methods: The website was developed in two phases. The first phase of development included expert group discussion, Focus Group Discussion (FGD), and the implementation of FGD recommendations. The second phase emphasised registration and development of the interactive web portal on OXIS classification. The developed website was subjected to user experience testing, functional testing, performance testing, security testing, device, platform testing, and then hosted. Calibrated students and faculties evaluated it with the help of Suitability Assessment of Materials (SAM) and System Usability Scale (SUS). Finally, after amendments, the website was evaluated by non-calibrated researchers and multidisciplinary experts.

Results: The total agreement was 74% for overall SAM category. Pooled mean total score of SUS was 52.7 (SD 7.17; range 45-67.5), indicating an average score.

Conclusion: The content of the developed website has been evaluated as "satisfactory" and its technical quality as "of higher standards".

目的:根尖间接触区的变化可分为开放接触区(O)、点接触区(X)、直接触区(I)和弯接触区(S)。这是根据它们的形状划分的,称为 OXIS 分类。开发互动式 OXIS 校准网站的目的是帮助研究人员寻求适当的知识,最大限度地减少过多的资料,优化校准效率,并为临床医生、医疗工作者和决策者提供资料库:该网站分两个阶段开发。第一阶段的开发包括专家组讨论、焦点小组讨论(FGD)和落实 FGD 建议。第二阶段的重点是注册和开发 OXIS 分类互动门户网站。开发的网站经过了用户体验测试、功能测试、性能测试、安全测试、设备和平台测试,然后托管。经过校准的学生和教师借助材料适用性评估(SAM)和系统可用性量表(SUS)对网站进行了评估。最后,在对网站进行修改后,由未经校准的研究人员和多学科专家对网站进行评估:结果:SAM 类别的总体一致率为 74%。SUS总分的合计平均值为52.7(标准差为7.17;范围为45-67.5),表明得分一般:结论:所开发网站的内容被评为 "令人满意",其技术质量被评为 "较高标准"。
{"title":"Development of 'OXIS Classification' calibration website for dental researchers.","authors":"Tarun Walia, Murugan Satta Muthu, Sneha Suhas Patil, Raghavendra Manjunath Shetty","doi":"10.1007/s40368-024-00908-4","DOIUrl":"10.1007/s40368-024-00908-4","url":null,"abstract":"<p><strong>Purpose: </strong>The variations in interproximal contact areas have been categorised open (O), point (X), straight (I), and curved contact (S). This is based on their shapes and termed as OXIS classification. The interactive OXIS calibration website was developed to assist researchers seeking appropriate knowledge, minimise the overload of material, optimise efficiency in calibration and, to provide repositories for clinicians, healthcare workers, and policymakers.</p><p><strong>Methods: </strong>The website was developed in two phases. The first phase of development included expert group discussion, Focus Group Discussion (FGD), and the implementation of FGD recommendations. The second phase emphasised registration and development of the interactive web portal on OXIS classification. The developed website was subjected to user experience testing, functional testing, performance testing, security testing, device, platform testing, and then hosted. Calibrated students and faculties evaluated it with the help of Suitability Assessment of Materials (SAM) and System Usability Scale (SUS). Finally, after amendments, the website was evaluated by non-calibrated researchers and multidisciplinary experts.</p><p><strong>Results: </strong>The total agreement was 74% for overall SAM category. Pooled mean total score of SUS was 52.7 (SD 7.17; range 45-67.5), indicating an average score.</p><p><strong>Conclusion: </strong>The content of the developed website has been evaluated as \"satisfactory\" and its technical quality as \"of higher standards\".</p>","PeriodicalId":47603,"journal":{"name":"European Archives of Paediatric Dentistry","volume":" ","pages":"501-511"},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140960268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of parent-reported timing of first tooth emergence and ECC: a secondary analysis of a case-control study. 家长报告的第一颗牙齿萌出时间与幼儿保育中心的关系:一项病例对照研究的二次分析。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-06-04 DOI: 10.1007/s40368-024-00914-6
M S Muthu, A Ganesh, S Anandan, G Thiruvengadam, R Padmanabhan, S Nuvvula

Purpose: Tooth eruption is a dynamic process. Appearance of any part of the cusp through gingiva may be a clinical marker of eruption. Early childhood caries (ECC) is a public health problem globally. This study aimed to assess the relationship between parent-reported timing of first tooth emergence and ECC in toddlers.

Methods: This study is a secondary data analysis of 627 toddlers involved in a case-control study on sleep-time feeding practises in children. The children were categorised into four groups based on the parent-reported timing of first primary tooth emergence (G1-when the first primary tooth emerged before 6 months of age, G2-between 7 and 9 months; G3-10 to 12 months and G4-when the first primary tooth emerged after 12 months of age). Univariate binary logistic regression analysis was performed to evaluate the association between timing of first tooth emergence and ECC.

Results: The mean age of the children was 24.4 ± 7.3 months (cases, that is children with ECC-25.4 ± 6.9 months, controls, that is children without ECC-23.6 ± 7.5 months). Of 60 children, whose first tooth erupted before 6 months of age, 35 (12%) were cases compared to 25(8%) controls. Amongst the cases, boys had more caries than girls (p < 0.05). Of the anterior teeth, 22% of the emerged teeth were decayed in the first group, followed by 19%, 16% and 10% in the second, third and fourth groups, respectively (p < 0.05). Analysis of the posterior teeth showed a lower percentage of decayed teeth with delayed emergence of the first primary tooth (p < 0.05). Children whose teeth emerged before 6 months of age had an odds ratio of 3.5 (95% CI 1.49, 8.42) (p = 0.004).

Conclusion: This study concluded that the early emergence of the first primary tooth, as reported by the parent, was associated with an increased risk of developing ECC.

目的:牙齿萌出是一个动态过程。通过牙龈出现尖牙的任何部分都可能是萌出的临床标志。儿童早期龋齿(ECC)是一个全球性的公共卫生问题。本研究旨在评估家长报告的幼儿第一颗牙齿萌出时间与 ECC 之间的关系:本研究对参与儿童睡眠时间喂养方式病例对照研究的 627 名幼儿进行了二次数据分析。根据家长报告的第一颗乳牙萌出的时间,这些儿童被分为四组(G1--第一颗乳牙萌出的时间在6个月之前;G2--第一颗乳牙萌出的时间在7至9个月之间;G3--第一颗乳牙萌出的时间在10至12个月之间;G4--第一颗乳牙萌出的时间在12个月之后)。研究人员进行了单变量二元逻辑回归分析,以评估第一颗乳牙萌出时间与 ECC 之间的关联:结果:儿童的平均年龄为 24.4 ± 7.3 个月(病例,即患有 ECC 的儿童-25.4 ± 6.9 个月;对照组,即未患有 ECC 的儿童-23.6 ± 7.5 个月)。在 60 名在 6 个月前萌出第一颗牙齿的儿童中,35 名(12%)为病例,对照组为 25 名(8%)。在病例中,男孩的龋齿发生率高于女孩(P本研究的结论是,家长报告的第一颗乳牙萌出时间过早与罹患 ECC 的风险增加有关。
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引用次数: 0
Chemotherapy-induced oral mucositis: hierarchical analysis of recurrence factors. 化疗引起的口腔黏膜炎:复发因素的层次分析。
IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-07-05 DOI: 10.1007/s40368-024-00919-1
T S de Macêdo, M C F de Melo, A K A Ferreira, E L M S da Silva-Selva, G P Godoy, A de F Caldas Júnior

Purpose: This study aimed to analyze, through a hierarchical model, the risk factors associated with the recurrence of chemo-induced oral mucositis (OM) in children and adolescents.

Methods: A retrospective cohort with 31 individuals of both sexes, aged 1-18 years, who were undergoing chemotherapy, and presented OM lesions was conducted. Data collection included analysis of medical records, interviews, and intraoral examination. Information regarding patients' socioeconomic and demographic profile, underlying disease, antineoplastic regimen, hematological condition, and oral health status were collected. To assess the association of independent variables with the outcome, the Chi-square, Fisher's Exact, and Mann-Whitney tests were used, in addition to a binary logistic regression model, with a maximum error of 5% and a 95% confidence interval.

Results: Significant associations were observed between the history of OM and the diagnosis of the child/adolescent, neutrophil count, previous cancer treatments and the chemotherapy scheme in use (p < 0.05). Binary logistic regression revealed a 13.69 higher risk of developing OM recurrence in individuals who received high-dose methotrexate (MTX) therapy.

Conclusion: Socioeconomic and demographic factors did not influence OM recurrence. However, clinical variables, such as neutropenia, diagnosis of leukemia, and high-dose MTX protocols increase the chance of OM new cases.

目的:本研究旨在通过层次模型分析与儿童和青少年化疗引起的口腔黏膜炎(OM)复发相关的风险因素:方法:对 31 名正在接受化疗并出现口腔黏膜炎病变的 1-18 岁男女患者进行了回顾性队列研究。数据收集包括病历分析、访谈和口腔内检查。收集的信息涉及患者的社会经济和人口概况、基础疾病、抗肿瘤疗法、血液状况和口腔健康状况。为了评估自变量与结果之间的关系,除了使用二元逻辑回归模型(最大误差为 5%,置信区间为 95%)外,还使用了卡方检验(Chi-square)、费雪精确检验(Fisher's Exact)和曼惠特尼检验(Mann-Whitney):观察发现,OM 病史与儿童/青少年的诊断、中性粒细胞计数、既往癌症治疗和正在使用的化疗方案之间存在显著关联(p 结论:OM 病史与儿童/青少年的诊断、中性粒细胞计数、既往癌症治疗和正在使用的化疗方案之间存在显著关联:社会经济和人口学因素不会影响 OM 复发。然而,中性粒细胞减少症、白血病诊断和大剂量 MTX 方案等临床变量会增加 OM 新病例的发生几率。
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引用次数: 0
期刊
European Archives of Paediatric Dentistry
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