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The association of adverse birth outcomes with flood exposure before and during pregnancy in Australia: a cohort study 在澳大利亚,不良出生结果与怀孕前和怀孕期间遭受洪水影响的关系:一项队列研究。
IF 24.1 1区 医学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 DOI: 10.1016/S2542-5196(24)00142-6
Zhengyu Yang MPH , Wenzhong Huang MPH , Prof Joanne E McKenzie PhD , Pei Yu PhD , Yao Wu MSc , Rongbin Xu PhD , Tingting Ye MSc , Ke Ju MSc , Yiwen Zhang MSc , Yujia Huang BSc , Prof Yuming Guo PhD , Prof Shanshan Li PhD

Background

Exposure to floods might increase the risks of adverse birth outcomes. However, the current evidence is scarce, inconsistent, and has knowledge gaps. This study aims to estimate the associations of flood exposure before and during pregnancy with adverse birth outcomes and to identify susceptible exposure windows and effect modifiers.

Methods

In this cohort study, we obtained all the birth records occurring in Greater Sydney, Australia, from Jan 1, 2001, to Dec 31, 2020, from the New South Wales Midwives Data Collection and in the Brisbane metropolitan region, Australia, from Jan 1, 1995, to Dec 31, 2014, from the Queensland Health Perinatal Data Collection. For each birth, residential address and historical flood information from the Dartmouth Flood Observatory were used to estimate the numbers of days with floods during five exposure windows (Pre-1 was defined as 13–24 weeks before the last menstrual period [LMP], Pre-2 was 0–12 weeks before the LMP, trimester 1 [Tri-1] was 0–12 weeks after the LMP, trimester 2 [Tri-2] was 13–28 weeks after the LMP, and trimester 3 [Tri-3] was ≥29 weeks after the LMP). We estimated the hazard ratios (HRs) of adverse birth outcomes (preterm births, stillbirths, term low birthweight [TLBW], and small for gestational age [SGA]) associated with flood exposures in the five exposure windows using Cox proportional hazards regression models.

Findings

1 338 314 birth records were included in our analyses, which included 91 851 (6·9%) preterm births, 9831 (0·7%) stillbirths, 25 567 (1·9%) TLBW, and 108 658 (8·1%) SGA. Flood exposure in Pre-1 was associated with increased risks of TLBW (HR 1·06 [95% CI 1·01–1·12]) and SGA (1·04 [1·01–1·06]); flood exposure during Tri-1 was associated with increased risks of preterm births (1·03 [1·002–1·05]), stillbirth (1·11 [1·03–1·20]), and SGA (1·03 [1·01–1·06]). In contrast, flood exposures during Pre-2 and Tri-3 were associated with reduced risks.

Interpretation

Exposures to floods in Pre-1 and Tri-1 are both associated with increased risks of adverse birth outcomes, and the risks increase with a higher exposure. Upon planning for conception and prenatal care, individuals and health practitioners should raise awareness of the increased risks of adverse birth outcomes after experiencing floods.

Funding

The Australian Research Council and the Australian National Health and Medical Research Council.

背景:洪水可能会增加不良出生结果的风险。然而,目前的证据很少、不一致,而且存在知识空白。本研究旨在估算孕前和孕期暴露于洪水与不良出生结局之间的关联,并确定易受影响的暴露窗口和效应调节因素:在这项队列研究中,我们从新南威尔士州助产士数据收集中获得了澳大利亚大悉尼地区 2001 年 1 月 1 日至 2020 年 12 月 31 日期间的所有出生记录,从昆士兰州卫生围产期数据收集中获得了澳大利亚布里斯班大都会地区 1995 年 1 月 1 日至 2014 年 12 月 31 日期间的所有出生记录。我们使用达特茅斯洪水观测站(Dartmouth Flood Observatory)提供的每个新生儿的居住地址和历史洪水信息来估算五个暴露窗口(Pre-1定义为末次月经期[LMP]前13-24周,Pre-2为末次月经期前0-12周,孕期1[Tri-1]为末次月经期后0-12周,孕期2[Tri-2]为末次月经期后13-28周,孕期3[Tri-3]为末次月经期后≥29周)中发生洪水的天数。我们使用 Cox 比例危险回归模型估算了五个暴露窗口中与洪水暴露相关的不良出生结局(早产、死胎、过期低出生体重[TLBW]和小于胎龄[SGA])的危险比(HRs):我们分析了 1 338 314 份出生记录,其中包括 91 851 例早产(6-9%)、9831 例死胎(0-7%)、25 567 例 TLBW(1-9%)和 108 658 例 SGA(8-1%)。在 Pre-1 期洪水暴露与 TLBW(HR 1-06 [95% CI 1-01-1-12])和 SGA(1-04 [1-01-1-06])风险增加有关;在 Tri-1 期洪水暴露与早产(1-03 [1-002-1-05])、死胎(1-11 [1-03-1-20])和 SGA(1-03 [1-01-1-06])风险增加有关。相比之下,Pre-2 和 Tri-3 期间的洪水暴露与风险降低有关:解释:在孕前 1 周和孕前 3 周暴露于洪水都会增加不良分娩结局的风险,而且暴露程度越高,风险越大。在计划受孕和产前护理时,个人和医疗从业人员应提高对遭遇洪灾后不良生育后果风险增加的认识:澳大利亚研究委员会和澳大利亚国家健康与医学研究委员会。
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引用次数: 0
Digital planetary health needs ethical guidance 数字地球健康需要伦理指导。
IF 24.1 1区 医学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 DOI: 10.1016/S2542-5196(24)00164-5
Eric C Ip
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引用次数: 0
Quantifying urban park use in the USA at scale: empirical estimates of realised park usage using smartphone location data 大规模量化美国城市公园的使用情况:利用智能手机定位数据对公园实际使用情况进行实证估算。
IF 24.1 1区 医学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 DOI: 10.1016/S2542-5196(24)00125-6
Michael T Young PhD , Swapnil Vispute MS , Stylianos Serghiou PhD MD , Akim Kumok MS , Yash Shah BS , Kevin J Lane PhD , Flannery Black-Ingersoll MPH , Paige Brochu PhD , Monica Bharel MD MPH , Sarah Skenazy MPH , Alan Karthikesalingam PhD MD , Shailesh Bavadekar BE , Mansi Kansal MBA , Tomer Shekel MBA , Evgeniy Gabrilovich PhD , Gregory A Wellenius ScD

Background

A large body of evidence connects access to greenspace with substantial benefits to physical and mental health. In urban settings where access to greenspace can be limited, park access and use have been associated with higher levels of physical activity, improved physical health, and lower levels of markers of mental distress. Despite the potential health benefits of urban parks, little is known about how park usage varies across locations (between or within cities) or over time.

Methods

We estimated park usage among urban residents (identified as residents of urban census tracts) in 498 US cities from 2019 to 2021 from aggregated and anonymised opted-in smartphone location history data. We used descriptive statistics to quantify differences in park usage over time, between cities, and across census tracts within cities, and used generalised linear models to estimate the associations between park usage and census tract level descriptors.

Findings

In spring (March 1 to May 31) 2019, 18·9% of urban residents visited a park at least once per week, with average use higher in northwest and southwest USA, and lowest in the southeast. Park usage varied substantially both within and between cities; was unequally distributed across census tract-level markers of race, ethnicity, income, and social vulnerability; and was only moderately correlated with established markers of census tract greenspace. In spring 2019, a doubling of walking time to parks was associated with a 10·1% (95% CI 5·6–14·3) lower average weekly park usage, adjusting for city and social vulnerability index. The median decline in park usage from spring 2019 to spring 2020 was 38·0% (IQR 28·4–46·5), coincident with the onset of physical distancing policies across much of the country. We estimated that the COVID-19-related decline in park usage was more pronounced for those living further from a park and those living in areas of higher social vulnerability.

Interpretation

These estimates provide novel insights into the patterns and correlates of park use and could enable new studies of the health benefits of urban greenspace. In addition, the availability of an empirical park usage metric that varies over time could be a useful tool for assessing the effectiveness of policies intended to increase such activities.

Funding

Google.

背景:大量证据表明,使用绿地对身心健康大有裨益。在绿地有限的城市环境中,公园的进入和使用与较高水平的体育活动、身体健康的改善以及较低水平的精神压力有关。尽管城市公园具有潜在的健康益处,但人们对公园使用率在不同地点(城市之间或城市内部)或不同时间的变化却知之甚少:我们通过汇总和匿名的智能手机定位历史数据,估算了 2019 年至 2021 年美国 498 个城市的城市居民(城市人口普查区的居民)的公园使用率。我们使用描述性统计来量化公园使用率在不同时期、不同城市之间以及城市内不同人口普查区之间的差异,并使用广义线性模型来估计公园使用率与人口普查区级别描述符之间的关联:2019 年春季(3 月 1 日至 5 月 31 日),18%-9% 的城市居民每周至少游览一次公园,美国西北部和西南部的平均使用率较高,东南部最低。在城市内部和城市之间,公园使用率差异很大;在人口普查区一级的种族、民族、收入和社会脆弱性指标中,公园使用率分布不均;与人口普查区绿地的既定指标仅有适度相关性。在2019年春季,根据城市和社会脆弱性指数进行调整后,步行到公园的时间每增加一倍,平均每周公园使用率就会降低10-1%(95% CI 5-6-14-3)。从 2019 年春季到 2020 年春季,公园使用率的中位数下降了 38-0%(IQR 28-4-46-5),这与全国大部分地区开始实施物理距离政策相吻合。我们估计,与 COVID-19 相关的公园使用率下降对于那些居住在距离公园较远的地区和那些居住在社会脆弱性较高的地区的人来说更为明显:这些估计结果为了解公园使用的模式和相关因素提供了新的视角,有助于对城市绿地的健康益处进行新的研究。此外,提供一个随时间变化的经验性公园使用指标,可以成为评估旨在增加此类活动的政策效果的有用工具:资助:谷歌
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引用次数: 0
Confronting heat-related illnesses and deaths at mass gathering religious and sporting events 在群众聚集的宗教和体育活动中应对与高温有关的疾病和死亡。
IF 24.1 1区 医学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 DOI: 10.1016/S2542-5196(24)00161-X
Brian McCloskey , Ziad A Memish , Avinash Sharma , Tieble Traore , Salim Parker , Alimuddin Zumla
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引用次数: 0
Health and climate policy 健康与气候政策。
IF 24.1 1区 医学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 DOI: 10.1016/S2542-5196(24)00173-6
The Lancet Planetary Health
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引用次数: 0
Seasons of smoke and fire: preparing health systems for improved performance before, during, and after wildfires 烟与火的季节:在野火发生之前、期间和之后,让卫生系统为提高绩效做好准备。
IF 24.1 1区 医学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 DOI: 10.1016/S2542-5196(24)00144-X
Attila J Hertelendy PhD , Courtney Howard MD , Cecilia Sorensen MD , Jamie Ranse PhD , Ejemai Eboreime MD PhD , Sarah Henderson PhD , Jeffrey Tochkin MA , Gregory Ciottone MD

Increased frequency, intensity, and duration of wildfires are intensifying exposure to direct and smoke-related hazards in many areas, leading to evacuation and smoke-related effects on health and health systems that can affect regions extending over thousands of kilometres. Effective preparation and response are currently hampered by inadequate training, continued siloing of disciplines, insufficient finance, and inadequate coordination between health systems and governance at municipal, regional, national, and international levels. This Review highlights the key health and health systems considerations before, during, and after wildfires, and outlines how a health system should respond to optimise population health outcomes now and into the future. The focus is on the implications of wildfires for air quality, mental health, and emergency management, with elements of international policy and finance also addressed. We discuss commonalities of existing climate-resilient health care and disaster management frameworks and integrate them into an approach that addresses issues of financing, leadership and governance, health workforce, health information systems, infrastructure, supply chain, technologies, community interaction and health-care delivery, before, during, and after a wildfire season. This Review is a practical briefing for leaders and health professionals facing severe wildfire seasons and a call to break down silos and join with other disciplines to proactively plan for and fund innovation and coordination in service of a healthier future.

野火发生的频率、强度和持续时间增加,加剧了许多地区暴露于直接危害和烟雾相关危害的程度,导致疏散和烟雾对健康和卫生系统的影响,这些影响可波及数千公里的区域。目前,有效的准备和应对工作受到以下因素的阻碍:培训不足、各学科继续各自为政、资金不足以及市、地区、国家和国际各级卫生系统和治理之间的协调不足。本综述强调了野火发生之前、期间和之后卫生和卫生系统的主要考虑因素,并概述了卫生系统应如何应对,以优化现在和未来的人口健康结果。重点是野火对空气质量、心理健康和应急管理的影响,同时也涉及国际政策和财政等因素。我们讨论了现有抵御气候变化的医疗保健和灾害管理框架的共性,并将其整合到一种方法中,以解决野火季节之前、期间和之后的融资、领导力和治理、医疗劳动力、医疗信息系统、基础设施、供应链、技术、社区互动和医疗保健服务等问题。本综述为面临严重野火季节的领导者和卫生专业人员提供了一份实用的简报,并呼吁打破各自为政的局面,与其他学科联合起来,积极规划和资助创新与协调,为更健康的未来服务。
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引用次数: 0
Where and how to invest in greenspace for optimal health benefits: a systematic review of greenspace morphology and human health relationships 在何处以及如何投资绿地以获得最佳健康效益:绿地形态与人类健康关系的系统回顾。
IF 24.1 1区 医学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 DOI: 10.1016/S2542-5196(24)00140-2
Huaqing Wang PhD , Simin Gholami MSc , Wenyan Xu PhD , Amirhossein Samavatekbatan MSc , Ole Sleipness PhD , Prof Louis G Tassinary PhD JD

Research on the relationship between greenspace morphology and health is a growing field that informs the spatial design of greenspace to enhance health outcomes. This study reviews the current progress, methodologies, and knowledge gaps in this area. From a database search of 272 940 English articles and 39 053 Chinese articles up to April 18, 2024, we identified 22 and 7 studies on the topic for further evaluation. Predominantly cross-sectional and neighbourhood-scale analyses were conducted using land cover maps ranging from 0·25 to 100 meters in resolution. Six primary characteristics of greenspace morphology have been studied, including size, shape, fragmentation, connectedness, aggregation, and diversity. While associations between greenspace morphology and health outcomes have been observed, both their reliability and generalisability remain suggestive due to ecological study designs and heterogeneity among studies. Future research should prioritise individual-level prospective cohorts and intervention studies. Exploring mechanisms linking greenspace morphology and health, determining optimal map resolution, and distinguishing it from greenness magnitude in statistical analysis is essential. This evidence is crucial for health-promoting greenspace planning and should be routinely integrated into urban epidemiological research.

绿地形态与健康之间关系的研究是一个不断发展的领域,它为绿地的空间设计提供信息,以提高健康效果。本研究回顾了这一领域目前的进展、方法和知识差距。通过数据库检索截至 2024 年 4 月 18 日的 272 940 篇英文文章和 39 053 篇中文文章,我们分别发现了 22 项和 7 项有关该主题的研究,以供进一步评估。我们使用分辨率从 0-25 米到 100 米不等的土地覆被图进行了以横断面和街区尺度为主的分析。研究了绿地形态的六个主要特征,包括大小、形状、破碎度、连通性、聚集度和多样性。虽然已观察到绿地形态与健康结果之间的关联,但由于生态研究设计和研究之间的异质性,其可靠性和普遍性仍有待进一步研究。未来的研究应优先考虑个人层面的前瞻性队列和干预研究。探索绿地形态与健康之间的关联机制、确定最佳地图分辨率以及在统计分析中区分绿地形态与绿化程度至关重要。这些证据对于促进健康的绿地规划至关重要,应定期纳入城市流行病学研究。
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引用次数: 0
Political restoration 政治恢复。
IF 24.1 1区 医学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-07-01 DOI: 10.1016/S2542-5196(24)00146-3
The Lancet Planetary Health
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引用次数: 0
Stemming the rising tide of Vibrio disease 遏制弧菌疾病的上升趋势。
IF 24.1 1区 医学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-07-01 DOI: 10.1016/S2542-5196(24)00124-4
Craig Baker-Austin PhD , Prof Iain Lake PhD , Elizabeth Archer PhD , Rachel Hartnell PhD , Prof Joaquin Trinanes PhD , Prof Jaime Martinez-Urtaza PhD

Globally, the diverse bacterial genus Vibrio is the most important group of bacterial pathogens found in marine and coastal waters. These bacteria can cause an array of human infections via direct exposure to seawater or through the consumption of seafoods grown and cultivated in coastal and estuarine settings. Crucially, we appear to be on the cusp of an alarming global increase in Vibrio disease. A worldwide increase in seafood consumption, the globalisation of the seafood trade, the more frequent use of coastal waters for recreational activities, and climate change all contribute to greatly increased human health risks associated with Vibrio bacteria. Coupled with a population that is increasingly susceptible to more serious infections, we are likely to see a marked increase in both reported cases and fatalities in the near future. In this Personal View, we discuss and frame this important and emerging public health issue, and provide various contemporary case studies to illustrate how the risk profiles of pathogenic Vibrio bacteria have transformed in the past two decades—particularly in response to changing climatological and meteorological drivers such as marine coastal warming and extreme weather events such as heatwaves and storms. We share various approaches to help better understand and manage risks associated with these bacteria, ranging from risk mitigation strategies to enhanced epidemiological monitoring and surveillance approaches.

在全球范围内,弧菌属细菌种类繁多,是海洋和沿海水域中最重要的细菌病原体。这些细菌可通过直接接触海水或通过食用在沿海和河口环境中生长和养殖的海产品引起一系列人类感染。至关重要的是,我们似乎正处于弧菌疾病在全球范围内惊人增长的边缘。全球海产品消费量的增加、海产品贸易的全球化、更频繁地使用沿海水域进行娱乐活动以及气候变化,都会大大增加与弧菌有关的人类健康风险。再加上人们越来越容易受到更严重的感染,在不久的将来,我们很可能会看到报告病例和死亡人数都会显著增加。在这篇《个人观点》中,我们讨论并阐述了这一新出现的重要公共卫生问题,并提供了各种当代案例研究,以说明致病性弧菌的风险特征在过去二十年中发生了怎样的变化--尤其是在应对气候和气象变化的驱动因素(如海洋沿岸变暖以及热浪和风暴等极端天气事件)方面。我们分享了有助于更好地了解和管理与这些细菌有关的风险的各种方法,从风险缓解战略到强化流行病学监测和监控方法。
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引用次数: 0
High ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study 孕期环境温度过高与儿童患急性淋巴细胞白血病的风险:一项观察性研究。
IF 24.1 1区 医学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-07-01 DOI: 10.1016/S2542-5196(24)00121-9
Tormod Rogne PhD , Rong Wang PhD , Pin Wang PhD , Nicole C Deziel PhD , Prof Catherine Metayer PhD , Prof Joseph L Wiemels PhD , Kai Chen PhD , Joshua L Warren PhD , Prof Xiaomei Ma PhD

Background

High ambient temperature is increasingly common due to climate change and is associated with risk of adverse pregnancy outcomes. Acute lymphoblastic leukaemia is the most common malignancy in children, the incidence is increasing, and in the USA disproportionately affects Latino children. We aimed to investigate the potential association between high ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia.

Methods

We used data from California birth records (children born from Jan 1, 1982, to Dec 31, 2015) and California Cancer Registry (those diagnosed with childhood cancer in California from Jan 1, 1988, to Dec 31, 2015) to identify acute lymphoblastic leukaemia cases diagnosed in infants and children aged 14 years and younger and controls matched by sex, race, ethnicity, and date of last menstrual period. Ambient temperatures were estimated on a 1-km grid. The association between ambient temperature and acute lymphoblastic leukaemia was evaluated per gestational week, restricted to May–September, adjusting for confounders. Bayesian meta-regression was applied to identify critical exposure windows. For sensitivity analyses, we evaluated a 90-day pre-pregnancy period (assuming no direct effect before pregnancy), adjusted for relative humidity and particulate matter less than 2·5 microns in aerodynamic diameter, and constructed an alternatively matched dataset for exposure contrast by seasonality.

Findings

6849 cases of childhood acute lymphoblastic leukaemia were identified and, of these, 6258 had sufficient data for study inclusion. We also included 307 579 matched controls. Most of the study population were male (174 693 [55·7%] of the 313 837 included in the study) and of Latino ethnicity (174 906 [55·7%]). The peak association between ambient temperature and risk of acute lymphoblastic leukaemia was observed in gestational week 8, where a 5°C increase was associated with an odds ratio of 1·07 (95% CI 1·04–1·11). A slightly larger effect was seen among Latino children (OR 1·09 [95% CI 1·04–1·14]) than non-Latino White children (OR 1·05 [1·00–1·11]). The sensitivity analyses supported the results of the main analysis.

Interpretation

Our findings suggest an association between high ambient temperature in early pregnancy and risk of childhood acute lymphoblastic leukaemia. Further replication and investigation of mechanistic pathways might inform mitigation strategies.

Funding

Yale Center on Climate Change and Health, The National Center for Advancing Translational Science, National Institutes of Health.

背景:由于气候变化,环境温度过高的现象越来越普遍,这与不良妊娠结局的风险有关。急性淋巴细胞白血病是儿童最常见的恶性肿瘤,发病率正在上升,在美国,拉丁裔儿童的发病率更高。我们旨在研究孕期环境温度过高与儿童急性淋巴细胞白血病风险之间的潜在关联:我们利用加州出生记录(1982 年 1 月 1 日至 2015 年 12 月 31 日出生的儿童)和加州癌症登记(1988 年 1 月 1 日至 2015 年 12 月 31 日在加州确诊为儿童癌症的儿童)中的数据,确定了确诊为急性淋巴细胞白血病的 14 岁及以下婴幼儿病例,以及按性别、种族、民族和末次月经日期匹配的对照组。环境温度按 1 公里网格估算。环境温度与急性淋巴细胞白血病之间的关系按孕周进行评估,时间仅限于 5 月至 9 月,并对混杂因素进行了调整。采用贝叶斯元回归法确定关键暴露窗口。在敏感性分析中,我们评估了孕前 90 天(假设孕前无直接影响),调整了相对湿度和空气动力直径小于 2-5 微米的颗粒物,并构建了一个替代匹配数据集,用于按季节性进行暴露对比:我们发现了 6849 例儿童急性淋巴细胞白血病病例,其中 6258 例病例的数据足以纳入研究。我们还纳入了 307 579 例匹配对照。研究对象中大部分为男性(313 837 例研究对象中的 174 693 例[55-7%])和拉丁裔(174 906 例[55-7%])。环境温度与罹患急性淋巴细胞白血病风险之间的关系在孕 8 周达到顶峰,温度每升高 5°C,几率比为 1-07(95% CI 1-04-1-11)。拉丁裔儿童的影响(OR 1-09 [95% CI 1-04-1-14])略大于非拉丁裔白人儿童(OR 1-05 [1-00-1-11])。敏感性分析支持主要分析的结果:我们的研究结果表明,孕早期环境温度过高与儿童急性淋巴细胞白血病的发病风险有关。对机理途径的进一步复制和调查可能会为缓解策略提供依据:耶鲁大学气候变化与健康中心、国家促进转化科学中心、美国国立卫生研究院。
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引用次数: 0
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Lancet Planetary Health
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