{"title":"Effect of functional electrical stimulation on maximum joint angles and gait asymmetry in female athletes post-anterior cruciate ligament reconstruction when crossing obstacles.","authors":"I-Lin Wang, Fei-Fei Lu, Si-Min Lian, Lijuan Chang, Yi-Ming Chen","doi":"10.1186/s13102-025-01486-8","DOIUrl":"https://doi.org/10.1186/s13102-025-01486-8","url":null,"abstract":"","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145971392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-13DOI: 10.1186/s13102-025-01514-7
Stanislav Dimitri Siegel, José Afonso, Ewan Thomas, Mareike Sproll, Astrid Zech, Gerit Plöschberger, Andreas Konrad, David G Behm, Jan Wilke, Robert Schleip, Konstantin Warneke
Foam rolling (FR) is commonly used in health and sports settings, yet it remains unclear how well current practice aligns with scientific evidence. We synthesised the available research on FR and compared it with practitioners' knowledge across professions and language-based cultural spheres.The evidence consistently supports acute increases in range of motion (ROM), short-term pain reduction, and transient improvements in muscle stiffness and blood flow. However, evidence for performance enhancement, injury prevention, and "fascial adhesion release" is limited or inconclusive, and data on safety are scarce.A cross-sectional online survey (n = 452; conducted in German, Italian, Portuguese, Spanish, and English-speaking countries) showed that only 2 of 15 evidence-based items reached the 80% correct response threshold. A simple majority answered just 10 items in accordance with current evidence, indicating substantial knowledge gaps. Accuracy varied by profession and cultural sphere.Overall, while FR is effective for acute ROM gains and pain relief, current beliefs about performance and long-term effects are not supported by robust evidence. The mismatch between research and practice highlights the need for clearer communication of findings, accessible continuing education, and evidence-based guidelines.Identified research gaps do not allow an appropriate judgement of the responses. This research gap calls for future research, while substantial effort should be invested into science communication to reach a broader audience.
{"title":"Effects of foam rolling and the knowledge-to-action gap: are practitioners' beliefs supported by the evidence? An international survey study.","authors":"Stanislav Dimitri Siegel, José Afonso, Ewan Thomas, Mareike Sproll, Astrid Zech, Gerit Plöschberger, Andreas Konrad, David G Behm, Jan Wilke, Robert Schleip, Konstantin Warneke","doi":"10.1186/s13102-025-01514-7","DOIUrl":"https://doi.org/10.1186/s13102-025-01514-7","url":null,"abstract":"<p><p>Foam rolling (FR) is commonly used in health and sports settings, yet it remains unclear how well current practice aligns with scientific evidence. We synthesised the available research on FR and compared it with practitioners' knowledge across professions and language-based cultural spheres.The evidence consistently supports acute increases in range of motion (ROM), short-term pain reduction, and transient improvements in muscle stiffness and blood flow. However, evidence for performance enhancement, injury prevention, and \"fascial adhesion release\" is limited or inconclusive, and data on safety are scarce.A cross-sectional online survey (n = 452; conducted in German, Italian, Portuguese, Spanish, and English-speaking countries) showed that only 2 of 15 evidence-based items reached the 80% correct response threshold. A simple majority answered just 10 items in accordance with current evidence, indicating substantial knowledge gaps. Accuracy varied by profession and cultural sphere.Overall, while FR is effective for acute ROM gains and pain relief, current beliefs about performance and long-term effects are not supported by robust evidence. The mismatch between research and practice highlights the need for clearer communication of findings, accessible continuing education, and evidence-based guidelines.Identified research gaps do not allow an appropriate judgement of the responses. This research gap calls for future research, while substantial effort should be invested into science communication to reach a broader audience.</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-12DOI: 10.1186/s13102-025-01524-5
Liangzhu Feng, Hongyou Liu
Background: Warm-up intensity is considered a key factor influencing acute physical performance, yet its specific effects on explosive power and agility in university football players remain unclear. This study compared the acute effects of low-, moderate-, and high-intensity warm-up on lower-limb explosive power and agility.
Methods: Twenty male university football athletes completed three 15-min warm-up protocols differing in intensity. Performance was assessed using the standing triple jump (STJ), 10 m sprint, 505 test, and T-test at pre-, post-, and post-10. Generalized mixed linear models were applied to evaluate the effects of intensity and time, with results reported as standardized effect sizes (ES) and 90% confidence limits (CL).
Results: The 10 m sprint performance was substantially better after the low-intensity warm-up than the moderate-intensity (ES; ± 90% CL: Post: 1.93; ± 0.64; Post-10: 3.31; ± 0.45) and high-intensity (Post: 1.90; ± 0.64; Post-10: 3.56; ± 0.65) warm-ups. The 505 test also showed superior performance after the low-intensity warm-up (vs. moderate: 1.55; ± 0.74, 1.16; ± 0.44; vs. high: 3.15; ± 0.72, 1.24; ± 0.44). Notably, in the 505 test (post: 1.6; ± 0.7; post-10: trivial), performance following the moderate-intensity warm-up at post was also substantially superior to that following the high-intensity warm-up. The T-test demonstrated a similar advantage (vs. moderate: 0.95; ± 0.23, 0.78; ± 0.22; vs. high: 0.86; ± 0.23, 0.73; ± 0.22). In contrast, the STJ (vs. low, post: 0.66; ± 0.31; post-10: 0.51; ± 0.31) improved only immediately after the moderate- and high-intensity warm-ups.
Conclusion: Low-intensity warm-up produced the most consistent and sustained improvements in sprint and agility performance. Moderate-intensity warm-up showed only a brief advantage in the 505 test, whereas high-intensity warm-up generally impaired speed and change-of-direction performance, with any explosive power gains being short-lived. These findings identify warm-up intensity as a key determinant of pre-competition readiness in male university football athletes.
{"title":"The impact of warm-up intensity on lower-limb explosive power and agility in male university football athletes.","authors":"Liangzhu Feng, Hongyou Liu","doi":"10.1186/s13102-025-01524-5","DOIUrl":"https://doi.org/10.1186/s13102-025-01524-5","url":null,"abstract":"<p><strong>Background: </strong>Warm-up intensity is considered a key factor influencing acute physical performance, yet its specific effects on explosive power and agility in university football players remain unclear. This study compared the acute effects of low-, moderate-, and high-intensity warm-up on lower-limb explosive power and agility.</p><p><strong>Methods: </strong>Twenty male university football athletes completed three 15-min warm-up protocols differing in intensity. Performance was assessed using the standing triple jump (STJ), 10 m sprint, 505 test, and T-test at pre-, post-, and post-10. Generalized mixed linear models were applied to evaluate the effects of intensity and time, with results reported as standardized effect sizes (ES) and 90% confidence limits (CL).</p><p><strong>Results: </strong>The 10 m sprint performance was substantially better after the low-intensity warm-up than the moderate-intensity (ES; ± 90% CL: Post: 1.93; ± 0.64; Post-10: 3.31; ± 0.45) and high-intensity (Post: 1.90; ± 0.64; Post-10: 3.56; ± 0.65) warm-ups. The 505 test also showed superior performance after the low-intensity warm-up (vs. moderate: 1.55; ± 0.74, 1.16; ± 0.44; vs. high: 3.15; ± 0.72, 1.24; ± 0.44). Notably, in the 505 test (post: 1.6; ± 0.7; post-10: trivial), performance following the moderate-intensity warm-up at post was also substantially superior to that following the high-intensity warm-up. The T-test demonstrated a similar advantage (vs. moderate: 0.95; ± 0.23, 0.78; ± 0.22; vs. high: 0.86; ± 0.23, 0.73; ± 0.22). In contrast, the STJ (vs. low, post: 0.66; ± 0.31; post-10: 0.51; ± 0.31) improved only immediately after the moderate- and high-intensity warm-ups.</p><p><strong>Conclusion: </strong>Low-intensity warm-up produced the most consistent and sustained improvements in sprint and agility performance. Moderate-intensity warm-up showed only a brief advantage in the 505 test, whereas high-intensity warm-up generally impaired speed and change-of-direction performance, with any explosive power gains being short-lived. These findings identify warm-up intensity as a key determinant of pre-competition readiness in male university football athletes.</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145960351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Return to sport (RTS) after anterior cruciate ligament reconstruction (ACLR) remains a critical issue in sports medicine. Despite improvements in rehabilitation, many patients fail to return to their preinjury level of activity. Previous studies have primarily focused on clinical and biomechanical factors that influence RTS; however, the impact of intrinsic physiological changes, particularly urinary proteomic profiles, has not yet been fully explored. This study aimed to identify potential urinary protein biomarkers associated with RTS in ACLR patients.
Methods: A total of 30 ACLR patients, at least 9 months post-surgery, were recruited. Patients were divided into RTS and non-RTS groups based on their ability to RTS, recovery to preinjury Tegner levels, and a leg symmetry index (LSI) of ≥ 85% on the single-leg hop (SLH) test. Furthermore, urine samples were analyzed using liquid chromatography-mass spectrometry to identify differentially expressed proteins associated with RTS. Potential biomarkers and mechanism associated with RTS were identified by series of bioinformatics and machine learning methods such as pathway enrichment methods, protein-protein interaction (PPI) network, the least absolute shrinkage and selection operator (LASSO), receiver operating characteristic curve and correlation analysis.
Results: Significant differences in knee muscle characteristics, including limb circumferences and isokinetic strength, were observed between the RTS and Non-RTS groups. A total of 3433 proteins were identified, with 20 upregulated and 58 downregulated in the RTS group. Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) analyses revealed key pathways including regulation of actin cytoskeleton, calcium ion binding, and Pathways related to inflammation such as IL-17 signaling pathway and neutrophil extracellular trap formation. Five proteins, including Glypican-3 (GPC3), Phosphatidylinositol transfer protein alpha isoform (PIPNA), Rap guanine nucleotide exchange factor 3 (RPGF3), Histone H1.5 (H15), and Small proline-rich protein 3 (SPRR3), were identified as potential biomarkers for evaluating RTS.
Conclusions: Muscle function was the primary factor influencing RTS after ACLR. The study revealed proteomic differences between those who RTS and those who do not. The identified potential biomarkers, such as GPC3, PIPNA, RPGF3, H15, and SPRR3, may serve as candidate targets to guide interventions designed to improve RTS outcomes following ACLR.
Trial registration: This study was registered in the Chinese Clinical Trial Registry (ChiCTR2200061779) on 02/07/2022.
{"title":"Alterations of urinary proteomic profiles are correlated with return to sport after anterior cruciate ligament reconstruction.","authors":"Ting Zhu, Yuanyuan Li, Yingqi Zhao, Yawei Gong, Jingbin Zhou, Xin Xu","doi":"10.1186/s13102-025-01527-2","DOIUrl":"10.1186/s13102-025-01527-2","url":null,"abstract":"<p><strong>Background: </strong>Return to sport (RTS) after anterior cruciate ligament reconstruction (ACLR) remains a critical issue in sports medicine. Despite improvements in rehabilitation, many patients fail to return to their preinjury level of activity. Previous studies have primarily focused on clinical and biomechanical factors that influence RTS; however, the impact of intrinsic physiological changes, particularly urinary proteomic profiles, has not yet been fully explored. This study aimed to identify potential urinary protein biomarkers associated with RTS in ACLR patients.</p><p><strong>Methods: </strong>A total of 30 ACLR patients, at least 9 months post-surgery, were recruited. Patients were divided into RTS and non-RTS groups based on their ability to RTS, recovery to preinjury Tegner levels, and a leg symmetry index (LSI) of ≥ 85% on the single-leg hop (SLH) test. Furthermore, urine samples were analyzed using liquid chromatography-mass spectrometry to identify differentially expressed proteins associated with RTS. Potential biomarkers and mechanism associated with RTS were identified by series of bioinformatics and machine learning methods such as pathway enrichment methods, protein-protein interaction (PPI) network, the least absolute shrinkage and selection operator (LASSO), receiver operating characteristic curve and correlation analysis.</p><p><strong>Results: </strong>Significant differences in knee muscle characteristics, including limb circumferences and isokinetic strength, were observed between the RTS and Non-RTS groups. A total of 3433 proteins were identified, with 20 upregulated and 58 downregulated in the RTS group. Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) analyses revealed key pathways including regulation of actin cytoskeleton, calcium ion binding, and Pathways related to inflammation such as IL-17 signaling pathway and neutrophil extracellular trap formation. Five proteins, including Glypican-3 (GPC3), Phosphatidylinositol transfer protein alpha isoform (PIPNA), Rap guanine nucleotide exchange factor 3 (RPGF3), Histone H1.5 (H15), and Small proline-rich protein 3 (SPRR3), were identified as potential biomarkers for evaluating RTS.</p><p><strong>Conclusions: </strong>Muscle function was the primary factor influencing RTS after ACLR. The study revealed proteomic differences between those who RTS and those who do not. The identified potential biomarkers, such as GPC3, PIPNA, RPGF3, H15, and SPRR3, may serve as candidate targets to guide interventions designed to improve RTS outcomes following ACLR.</p><p><strong>Trial registration: </strong>This study was registered in the Chinese Clinical Trial Registry (ChiCTR2200061779) on 02/07/2022.</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":" ","pages":"70"},"PeriodicalIF":2.8,"publicationDate":"2026-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12882355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145949090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-10DOI: 10.1186/s13102-025-01521-8
Wenxuan Yu, Zheng Zhou, Hui Zhang, Xiao Xie
Background: Table tennis is characterized by high intensity and short rallies, where the stability of technical and tactical execution is crucial to performance. Existing research on performance fluctuations has primarily focused on psychological or score-based metrics, neglecting the technical execution of strokes. To address this gap, this study introduces a novel metric: Stroke Performance Fluctuation (SPF).
Method: The dataset consists of 100 elite matches (50 male and 50 female matches) between 2021 and 2025, analyzing 2,163 rallies and 29,406 strokes. SPF is quantified as the deviation between Rally Winning Probability (RWP) and Expected Rally Winning Probability (ERWP). SPF values were also compared across gender, competitive level and games.
Results: (1) Male players exhibited significantly higher fluctuations than female players, particularly in Block, Flick, Push, Touch Short, Topspin, and Twist; (2) Top 20 players are more consistent than others in serving, receiving, and offensive techniques; (3) Performance in Touch Short against Pendulum and Topspin against Topspin exhibited a significant decline in the later stages of the match.
Conclusions: The SPF indicator provides a novel and effective measure of stroke behavior stability in elite table tennis. By quantifying fluctuations in technical and tactical performance, the SPF indicator reveals gender- and competition-level differences in stroke stability. In addition, we used performance deviation to describe how consistency changes across games within a match. This framework not only advances performance analysis beyond score-based or psychology-based measures but also offers practical applications for coaches, enabling targeted training and tactical interventions to reduce stroke instability and enhance competitive resilience.
{"title":"Stroke-level performance fluctuation analysis in elite table tennis.","authors":"Wenxuan Yu, Zheng Zhou, Hui Zhang, Xiao Xie","doi":"10.1186/s13102-025-01521-8","DOIUrl":"https://doi.org/10.1186/s13102-025-01521-8","url":null,"abstract":"<p><strong>Background: </strong>Table tennis is characterized by high intensity and short rallies, where the stability of technical and tactical execution is crucial to performance. Existing research on performance fluctuations has primarily focused on psychological or score-based metrics, neglecting the technical execution of strokes. To address this gap, this study introduces a novel metric: Stroke Performance Fluctuation (SPF).</p><p><strong>Method: </strong>The dataset consists of 100 elite matches (50 male and 50 female matches) between 2021 and 2025, analyzing 2,163 rallies and 29,406 strokes. SPF is quantified as the deviation between Rally Winning Probability (RWP) and Expected Rally Winning Probability (ERWP). SPF values were also compared across gender, competitive level and games.</p><p><strong>Results: </strong>(1) Male players exhibited significantly higher fluctuations than female players, particularly in Block, Flick, Push, Touch Short, Topspin, and Twist; (2) Top 20 players are more consistent than others in serving, receiving, and offensive techniques; (3) Performance in Touch Short against Pendulum and Topspin against Topspin exhibited a significant decline in the later stages of the match.</p><p><strong>Conclusions: </strong>The SPF indicator provides a novel and effective measure of stroke behavior stability in elite table tennis. By quantifying fluctuations in technical and tactical performance, the SPF indicator reveals gender- and competition-level differences in stroke stability. In addition, we used performance deviation to describe how consistency changes across games within a match. This framework not only advances performance analysis beyond score-based or psychology-based measures but also offers practical applications for coaches, enabling targeted training and tactical interventions to reduce stroke instability and enhance competitive resilience.</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145949095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-10DOI: 10.1186/s13102-025-01509-4
Rocco Salvatore Calabrò, Andrea Calderone, Maria Grazia Maggio, Francesco Speciale, Daniele Bruschetta, Maurizio Lanza, Angelo Quartarone
{"title":"Sport performance in virtual worlds: a systematic review of sport simulation in neurological paralympic athletes and non-athlete populations.","authors":"Rocco Salvatore Calabrò, Andrea Calderone, Maria Grazia Maggio, Francesco Speciale, Daniele Bruschetta, Maurizio Lanza, Angelo Quartarone","doi":"10.1186/s13102-025-01509-4","DOIUrl":"10.1186/s13102-025-01509-4","url":null,"abstract":"","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":" ","pages":"72"},"PeriodicalIF":2.8,"publicationDate":"2026-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12882567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145949093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1186/s13102-026-01528-9
Friew Amare, Alemmebrat Kiflu, Aschenaki Taddese
Background: Type 2 diabetes (T2DM) is linked to impaired metabolic and cardiovascular health, and concurrent exercise is a key intervention to enhance these outcomes. However, the effect of exercise sequence on these outcomes remains unclear. This study aimed to examine the effects of 12 weeks of concurrent training, performed in different sequences of aerobic and resistance exercise, on VO₂ Peak, glucose tolerance area under the curve (GT AUC), waist-to-hip ratio (WHR), and body mass index (BMI) in patients with T2DM.
Methods: In this randomized controlled trial, participants were allocated to Concurrent Aerobic-Resistance Training (CART = 13), Concurrent Resistance-Aerobic Training (CRAT = 13), or a control group (COG = 13). Training was conducted three times per week for 12 weeks. VO₂ Peak, GT AUC, WHR, and BMI were measured pre- and post-intervention. Data were analyzed using a mixed-model ANOVA to assess Group × Time interactions, followed, when significant, by Bonferroni-adjusted post hoc pairwise comparisons across groups to identify differences in intervention-related changes.
Results: Both CART and CRAT significantly improved VO₂ Peak, GT AUC, WHR, and BMI compared to the control group (p < .05). VO₂ Peak increased by 2.999 mL/kg/min in CART and 2.147 mL/kg/min in CRAT, while GT AUC decreased by 23.01 and 24.22 units, respectively, reflecting enhanced cardiovascular fitness and glucose tolerance. WHR decreased by 0.106 in CART and 0.095 in CRAT, whereas BMI reduction was greater in CART (2.76 kg/m²) than in CRAT (1.48 kg/m²), suggesting a potential effect of exercise sequence on obesity indices.
Conclusion: Twelve weeks of concurrent training effectively enhanced cardiovascular fitness, glycemic control, and obesity indices in T2DM patients. While both exercise sequences provided benefits, performing aerobic exercise before resistance training may maximize BMI reduction, whereas improvements in VO₂ Peak, reduction in WHR, and glucose tolerance occur regardless of exercise order. These findings support adopting flexible, evidence-based concurrent training programs for metabolic and cardiovascular health.
Trial registration: 02 September 2025, Registration no: PACTR202509591505325.
{"title":"Impact of concurrent training order on cardiorespiratory fitness, glucose tolerance, and obesity indices in type 2 diabetic patients: randomized controlled trial.","authors":"Friew Amare, Alemmebrat Kiflu, Aschenaki Taddese","doi":"10.1186/s13102-026-01528-9","DOIUrl":"10.1186/s13102-026-01528-9","url":null,"abstract":"<p><strong>Background: </strong>Type 2 diabetes (T2DM) is linked to impaired metabolic and cardiovascular health, and concurrent exercise is a key intervention to enhance these outcomes. However, the effect of exercise sequence on these outcomes remains unclear. This study aimed to examine the effects of 12 weeks of concurrent training, performed in different sequences of aerobic and resistance exercise, on VO₂ Peak, glucose tolerance area under the curve (GT AUC), waist-to-hip ratio (WHR), and body mass index (BMI) in patients with T2DM.</p><p><strong>Methods: </strong>In this randomized controlled trial, participants were allocated to Concurrent Aerobic-Resistance Training (CART = 13), Concurrent Resistance-Aerobic Training (CRAT = 13), or a control group (COG = 13). Training was conducted three times per week for 12 weeks. VO₂ Peak, GT AUC, WHR, and BMI were measured pre- and post-intervention. Data were analyzed using a mixed-model ANOVA to assess Group × Time interactions, followed, when significant, by Bonferroni-adjusted post hoc pairwise comparisons across groups to identify differences in intervention-related changes.</p><p><strong>Results: </strong>Both CART and CRAT significantly improved VO₂ Peak, GT AUC, WHR, and BMI compared to the control group (p < .05). VO₂ Peak increased by 2.999 mL/kg/min in CART and 2.147 mL/kg/min in CRAT, while GT AUC decreased by 23.01 and 24.22 units, respectively, reflecting enhanced cardiovascular fitness and glucose tolerance. WHR decreased by 0.106 in CART and 0.095 in CRAT, whereas BMI reduction was greater in CART (2.76 kg/m²) than in CRAT (1.48 kg/m²), suggesting a potential effect of exercise sequence on obesity indices.</p><p><strong>Conclusion: </strong>Twelve weeks of concurrent training effectively enhanced cardiovascular fitness, glycemic control, and obesity indices in T2DM patients. While both exercise sequences provided benefits, performing aerobic exercise before resistance training may maximize BMI reduction, whereas improvements in VO₂ Peak, reduction in WHR, and glucose tolerance occur regardless of exercise order. These findings support adopting flexible, evidence-based concurrent training programs for metabolic and cardiovascular health.</p><p><strong>Trial registration: </strong>02 September 2025, Registration no: PACTR202509591505325.</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":" ","pages":"69"},"PeriodicalIF":2.8,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12882170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145946634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1186/s13102-025-01511-w
Huimeng Chen, Qiujie Li, Ying Chen, Hui Liu, Xianglin Wan
{"title":"The effects of different types of dual-task gait training on lower-limb coordination during dual-task gait in patients with stroke: a single-blind randomized controlled trial.","authors":"Huimeng Chen, Qiujie Li, Ying Chen, Hui Liu, Xianglin Wan","doi":"10.1186/s13102-025-01511-w","DOIUrl":"10.1186/s13102-025-01511-w","url":null,"abstract":"","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":" ","pages":"68"},"PeriodicalIF":2.8,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12882171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1186/s13102-025-01518-3
Andreas Kopf, Maximilian Getzreiter, Andreas Wittke, Emre Nokay, Markus Gesslein, Volker Alt, Werner Krutsch, Dominik Szymski
<p><strong>Purpose: </strong>Anterior cruciate ligament (ACL) ruptures represent one of the most severe injuries in professional football, often resulting in long rehabilitation, impaired performance, and increased risk of re-injury. The aim of this study was to investigate whether performance parameters derived from match statistics can serve as early indicators of ACL rupture in professional male football players.</p><p><strong>Methods: </strong>A retrospective case-control design was applied. Forty-two male professional football players from the German Bundesliga and 2. Bundesliga with confirmed ACL ruptures between 2016 and 2024 were included, alongside 42 matched controls from the same teams and positions. Match performance data from ten games preceding the injury were analyzed. Parameters included minutes played, total distance covered, number of sprints, maximal speed, pass accuracy, number of duels, and duel success rate. Independent t-tests compared injured and control players across individual matchdays and aggregated intervals (the average values across the last four, three, and two matches before injury). Additionally, odds ratios (OR) with 95% confidence intervals were computed based on upper (≥ 75th percentile) and lower (≤ 25th percentile) quartile thresholds to quantify the relative risk associated with extreme performance values.</p><p><strong>Results: </strong>Injured players showed higher maximum speed that consistently differentiated them from controls, with significant differences at matchday 2 (p = 0.005, OR = 3.42, 95% CI 1.45-8.06) and across all aggregated intervals (p = 0.015-0.031). Injured players also showed significantly fewer minutes played at matchday 2 before injury (p = 0.046, OR = 2.36, 95% CI 1.01-5.51) and across certain intervals (last four and three matches before injury; p = 0.027-0.044). Analysis of matchdays 5-10 revealed no significant group differences for any performance parameter, confirming that relevant performance changes manifest primarily in the immediate pre-injury period. No significant group differences emerged for distance covered, sprint count, pass accuracy, or duel frequency between ACL injured players and controls.</p><p><strong>Conclusion: </strong>Maximum speed showed the strongest association with ACL rupture risk, with significant differences at matchday 2 (p = 0.005) and across aggregated intervals (the average values across the last four, three, and two matches before injury). Reduced playing time emerged as an additional indicator. Although distance covered, sprint count, and pass accuracy did not reach statistical significance individually, their temporal patterns revealed a predisposing risk constellation: injured players demonstrated reduced cumulative exposure combined with acute high-intensity spikes at matchday 2, declining technical precision, and increased physical confrontation at matchday 1. This suggests ACL injury risk manifests through deterioration of integrated perfo
目的:前交叉韧带(ACL)断裂是职业足球中最严重的损伤之一,通常会导致长期的康复,性能受损,并增加再次受伤的风险。本研究的目的是探讨从比赛数据中得出的表现参数是否可以作为职业男足球运动员ACL断裂的早期指标。方法:采用回顾性病例-对照设计。42名来自德甲的男性职业足球运动员和2名来自德国的职业足球运动员。2016年至2024年间确认ACL破裂的德甲联赛,以及来自相同球队和位置的42名匹配对照。分析了受伤前10场比赛的比赛表现数据。参数包括比赛时间、总距离、冲刺次数、最大速度、通过准确率、决斗次数和决斗成功率。独立的t检验比较了受伤球员和对照组球员在单个比赛日和汇总时间间隔(受伤前最后4场、3场和2场比赛的平均值)。此外,基于上(≥75百分位数)和下(≤25百分位数)四分位数阈值计算95%置信区间的比值比(OR),以量化与极端性能值相关的相对风险。结果:与对照组相比,受伤球员表现出更高的最大速度,在比赛日第2天(p = 0.005, OR = 3.42, 95% CI 1.45-8.06)和所有汇总区间(p = 0.015-0.031)存在显著差异。受伤球员在受伤前的第2个比赛日的上场时间也明显减少(p = 0.046, OR = 2.36, 95% CI 1.01-5.51),并且在一定的时间间隔内(受伤前的最后4场和3场比赛,p = 0.027-0.044)。对比赛日5-10的分析显示,在任何表现参数上,各组之间没有显著差异,证实了相关的表现变化主要体现在受伤前的那段时间。在前交叉韧带受伤的运动员和对照组之间,在覆盖距离、冲刺次数、传球准确性或对打频率方面没有显著的组间差异。结论:最大速度与前交叉韧带破裂风险的相关性最强,在比赛日第2天(p = 0.005)和整个累积时间间隔(受伤前最后4场、3场和2场比赛的平均值)存在显著差异。减少的游戏时间是一个额外的指标。尽管跑动距离、冲刺次数和传球准确率都不具有统计学意义,但它们的时间模式揭示了一个易诱发的风险组合:受伤球员在比赛日第二场表现出累积暴露减少,同时出现急性高强度峰值,技术精度下降,在比赛日第一场身体对抗增加。这表明前交叉韧带损伤风险表现为急性负荷波动下综合性能能力的恶化,而不是孤立的阈值。综合生物力学、生理和时间表现模式的多因素方法对于有效预防职业足球前交叉韧带损伤至关重要。
{"title":"Short-term - change on physical capacities of football players within few days before ACL-injury: a retrospective case-control study.","authors":"Andreas Kopf, Maximilian Getzreiter, Andreas Wittke, Emre Nokay, Markus Gesslein, Volker Alt, Werner Krutsch, Dominik Szymski","doi":"10.1186/s13102-025-01518-3","DOIUrl":"10.1186/s13102-025-01518-3","url":null,"abstract":"<p><strong>Purpose: </strong>Anterior cruciate ligament (ACL) ruptures represent one of the most severe injuries in professional football, often resulting in long rehabilitation, impaired performance, and increased risk of re-injury. The aim of this study was to investigate whether performance parameters derived from match statistics can serve as early indicators of ACL rupture in professional male football players.</p><p><strong>Methods: </strong>A retrospective case-control design was applied. Forty-two male professional football players from the German Bundesliga and 2. Bundesliga with confirmed ACL ruptures between 2016 and 2024 were included, alongside 42 matched controls from the same teams and positions. Match performance data from ten games preceding the injury were analyzed. Parameters included minutes played, total distance covered, number of sprints, maximal speed, pass accuracy, number of duels, and duel success rate. Independent t-tests compared injured and control players across individual matchdays and aggregated intervals (the average values across the last four, three, and two matches before injury). Additionally, odds ratios (OR) with 95% confidence intervals were computed based on upper (≥ 75th percentile) and lower (≤ 25th percentile) quartile thresholds to quantify the relative risk associated with extreme performance values.</p><p><strong>Results: </strong>Injured players showed higher maximum speed that consistently differentiated them from controls, with significant differences at matchday 2 (p = 0.005, OR = 3.42, 95% CI 1.45-8.06) and across all aggregated intervals (p = 0.015-0.031). Injured players also showed significantly fewer minutes played at matchday 2 before injury (p = 0.046, OR = 2.36, 95% CI 1.01-5.51) and across certain intervals (last four and three matches before injury; p = 0.027-0.044). Analysis of matchdays 5-10 revealed no significant group differences for any performance parameter, confirming that relevant performance changes manifest primarily in the immediate pre-injury period. No significant group differences emerged for distance covered, sprint count, pass accuracy, or duel frequency between ACL injured players and controls.</p><p><strong>Conclusion: </strong>Maximum speed showed the strongest association with ACL rupture risk, with significant differences at matchday 2 (p = 0.005) and across aggregated intervals (the average values across the last four, three, and two matches before injury). Reduced playing time emerged as an additional indicator. Although distance covered, sprint count, and pass accuracy did not reach statistical significance individually, their temporal patterns revealed a predisposing risk constellation: injured players demonstrated reduced cumulative exposure combined with acute high-intensity spikes at matchday 2, declining technical precision, and increased physical confrontation at matchday 1. This suggests ACL injury risk manifests through deterioration of integrated perfo","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":" ","pages":"63"},"PeriodicalIF":2.8,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12874991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-08DOI: 10.1186/s13102-025-01457-z
Yazhi Kang, Jianfei Wen, Tongwu Yu, Yufei Qi, Yunqing Li
<p><strong>Background: </strong>Normobaric hypoxia training (NHT) has emerged as a potentially superior exercise intervention for obesity management, theoretically offering enhanced metabolic stress and body composition benefits compared to normoxic exercise. However, optimal dose-response parameters remain undefined, limiting clinical translation and standardization of hypoxic exercise protocols.</p><p><strong>Objective: </strong>To comprehensively investigate dose-response relationships between NHT parameters and body composition/metabolic outcomes in adults with obesity through systematic review and meta-analysis.</p><p><strong>Methods: </strong>A systematic search of five databases (PubMed, Web of Science, Scopus, SPORTDiscus, CINAHL) was conducted from January 2014 to June 2025. Inclusion criteria comprised randomized controlled trials comparing NHT versus normoxic exercise in adults with BMI ≥ 25 kg/m². Primary outcomes included body weight, body fat percentage, BMI, fat mass, and waist circumference. Random-effects meta-analysis and univariate/multivariate meta-regression were employed for dose-response modelling. Dose parameters included fractional inspired oxygen (FiO₂), session duration, training frequency, intervention duration, and composite hypoxia dose scores.</p><p><strong>Results: </strong>Ten studies involving 301 participants were included. Contrary to theoretical expectations, NHT demonstrated no superior body composition benefits compared to normoxic exercise across primary outcomes: body weight (MD = 0.12 kg, 95% CI: -1.99 to 2.22, p = 0.89), body fat percentage (MD = 0.21%, 95% CI: -3.00 to 3.41, p = 0.87), BMI (MD = -0.34 kg/m², 95% CI: -0.16 to 0.85, p = 0.15), and waist circumference (MD = -1.26 cm, 95% CI: -9.38 to 6.87, p = 0.66). Fat mass increased in NHT groups (MD = 1.10 kg, 95% CI: 0.24 to 1.95, p = 0.02). None of the primary outcomes achieved pre-defined clinical significance thresholds. Comprehensive dose-response meta-regression examining six hypoxia parameters (FiO₂, session duration, frequency, intervention weeks, total exposure hours, composite dose score) revealed no statistically significant relationships with any body composition outcome (all p > 0.05, all R² = 0.0-15.5%). Moderate multicollinearity among dose variables (r = 0.688-0.995, max VIF = 6.45) precluded reliable multivariate modelling, though univariate analyses consistently demonstrated null dose-response effects across all parameter-outcome combinations, indicating absence of clear dose-response gradients within examined ranges. NHT showed a non-significant trend toward improved cardiovascular fitness (VO₂peak: MD = 1.43 mL/kg/min, 95% CI: -0.86 to 3.72, p = 0.16) though with moderate heterogeneity across studies (I² = 62%).</p><p><strong>Conclusions: </strong>This systematic review and meta-analysis found no evidence that normobaric hypoxia training produces superior body composition outcomes compared with equivalent normoxic exercise in adults
{"title":"Dose-response relationship of normobaric hypoxia training on body composition and metabolic health in obese adults: a systematic review and meta-analysis.","authors":"Yazhi Kang, Jianfei Wen, Tongwu Yu, Yufei Qi, Yunqing Li","doi":"10.1186/s13102-025-01457-z","DOIUrl":"https://doi.org/10.1186/s13102-025-01457-z","url":null,"abstract":"<p><strong>Background: </strong>Normobaric hypoxia training (NHT) has emerged as a potentially superior exercise intervention for obesity management, theoretically offering enhanced metabolic stress and body composition benefits compared to normoxic exercise. However, optimal dose-response parameters remain undefined, limiting clinical translation and standardization of hypoxic exercise protocols.</p><p><strong>Objective: </strong>To comprehensively investigate dose-response relationships between NHT parameters and body composition/metabolic outcomes in adults with obesity through systematic review and meta-analysis.</p><p><strong>Methods: </strong>A systematic search of five databases (PubMed, Web of Science, Scopus, SPORTDiscus, CINAHL) was conducted from January 2014 to June 2025. Inclusion criteria comprised randomized controlled trials comparing NHT versus normoxic exercise in adults with BMI ≥ 25 kg/m². Primary outcomes included body weight, body fat percentage, BMI, fat mass, and waist circumference. Random-effects meta-analysis and univariate/multivariate meta-regression were employed for dose-response modelling. Dose parameters included fractional inspired oxygen (FiO₂), session duration, training frequency, intervention duration, and composite hypoxia dose scores.</p><p><strong>Results: </strong>Ten studies involving 301 participants were included. Contrary to theoretical expectations, NHT demonstrated no superior body composition benefits compared to normoxic exercise across primary outcomes: body weight (MD = 0.12 kg, 95% CI: -1.99 to 2.22, p = 0.89), body fat percentage (MD = 0.21%, 95% CI: -3.00 to 3.41, p = 0.87), BMI (MD = -0.34 kg/m², 95% CI: -0.16 to 0.85, p = 0.15), and waist circumference (MD = -1.26 cm, 95% CI: -9.38 to 6.87, p = 0.66). Fat mass increased in NHT groups (MD = 1.10 kg, 95% CI: 0.24 to 1.95, p = 0.02). None of the primary outcomes achieved pre-defined clinical significance thresholds. Comprehensive dose-response meta-regression examining six hypoxia parameters (FiO₂, session duration, frequency, intervention weeks, total exposure hours, composite dose score) revealed no statistically significant relationships with any body composition outcome (all p > 0.05, all R² = 0.0-15.5%). Moderate multicollinearity among dose variables (r = 0.688-0.995, max VIF = 6.45) precluded reliable multivariate modelling, though univariate analyses consistently demonstrated null dose-response effects across all parameter-outcome combinations, indicating absence of clear dose-response gradients within examined ranges. NHT showed a non-significant trend toward improved cardiovascular fitness (VO₂peak: MD = 1.43 mL/kg/min, 95% CI: -0.86 to 3.72, p = 0.16) though with moderate heterogeneity across studies (I² = 62%).</p><p><strong>Conclusions: </strong>This systematic review and meta-analysis found no evidence that normobaric hypoxia training produces superior body composition outcomes compared with equivalent normoxic exercise in adults","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145918895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}